Paper of the Month

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Nat Commun 11, 5319 (2020). DZHK-Autoren: Ferdinand le Noble, Rabea Hinkel, Christian Kupatt

Exercise-Stress Real-time Cardiac Magnetic Resonance Imaging for Non-Invasive Characterisation of Heart Failure with Preserved Ejection Fraction: The HFpEF Stress Trial. Circulation. 2021 Jan 21. DZHK-Autoren: Sören J. Backhaus, Torben Lange, Elisabeth F. George, Kristian...

An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility. Circulation (2020), DZHK-Autoren: Alexandra Madsen, Grit Höppner, Julia Krause, Marc N. Hirt, Sandra D. Laufer, Thomas Eschenhagen, Justus Stenzig

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study. European Heart Journal (2020), DZHK-Autoren: David M...

Cells of the adult human heart. Nature 2020, DZHK-Autoren: Henrike Maatz, Daniel Reichart, Barbara McDonough, Norbert Hübner

A Minimal-Invasive Approach for Standardized Induction of Myocardial Infarction in Mice. Circulation Research, DZHK-Autoren: Florian Sicklinger, Yunhang Zhang, Lorenz Lehmann, Mathias H. Konstandin, Hugo A. Katus, Florian Leuschner

Immunothrombotic Dysregulation in COVID-19 Pneumonia is Associated with Respiratory Failure and Coagulopathy. CIRCULATION 28 Jul 2020, DZHK-Autoren: Leo Nicolai, Alexander Leunig, Rainer Kaiser, Tobias Weinberger, Clemens Scherer, Stefan Kääb, Steffen Massberg. Kami Pekayvaz,...

Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis. Science Translational Medicine (2020), DZHK-Autoren: D. Santovito, L. Natarelli, M. Aslani, E. Lutgens, P. von Hundelshausen, S. Steffens, J. Duchene, R.T.A....

Phosphodiesterase 3A and arterial hypertension. Circulation (2020) DZHK-Autoren: M. Ercu*, L. Markó*, C. Schächterle, D. Tsvetkov, T. U. P. Bartolomaeus, N. Hübner, S. K. Forslund, D. N. Müller, M. Gollasch, M. Bader, Friedrich C. Luft** and E. Klussmann**

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy. Nature Medicine, DZHK-Autoren: A. Moretti, P. Hoppmann, A. B. Meier, T. Bozoglu, A. Baehr, C. M. Schneider, D. Sinnecker, K. Klett, F. Abdel Rahman, T....