Project

Association of single nucleotide polymorphism (SNPs) within the MAP3K12 gene with cardiovascular risk factors

Project term: 01/2023 - 06/2023
Granted budget: no DZHK funding
Research resource used: DZHKomics resource
Keywords: MAP3K12, SNPs, cardiovascular risk factors
Principal Investigator: Elke Oetjen (University Medical Center Hamburg- Eppendorf, Institute of Clinical Pharmacology and Toxicology)

The mitogen-activated protein 3 kinase 12 (MAP3K12) alias dual leucine zipper kinase (DLK) is mainly involved in the pathogenesis of neurodegenerative diseases.

Our own studies indicate an involvement of DLK in the pathogenesis of diabetes mellitus type 2, an important risk factor for cardiovascular diseases. In this project, we aim to investigate whether SNPs within the DLK gene are associated with cardiovascular risk factors.

Publications

There are no publications available yet.