Molecular markers and new therapeutic targets in patients with inflammatory cardiomyopathy


Project term

12/2022 - 12/2026

Granted budget

no DZHK funding

Research resource used

Resource liquid samples/image data

Keywords

inflammatory cardiomyopathy, molecular markers, cytokine analysis

Principal Investigator

Bettina Heidecker, Benjamin Meder (Charité Universitätsmedizin Berlin, Campus Benjamin Franklin (CBF), Department of Cardiology and University Hospital Heidelberg, Institute for Cardiomyopathies)

The exact pathomechanisms of inflammatory cardiomyopathy continue to be relevant to current cardiovascular science.

This retrospective multicenter study investigates molecular markers and signaling pathways of inflammatory cardiomyopathies and interprets them in the context of clinical parameters including echocardiographic data. The goal is to find potential new therapeutic targets. A better understanding of the molecular mechanisms may improve diagnostic methods and future therapies. Data and samples from the TORCH-DZHK1 registry of the German Centre for Cardiovascular Research are used to validate the findings from the original derivation cohort. The study takes place at the Charité Universitätsmedizin Berlin, Campus Benjamin Franklin.

Publications

There are no publications available yet.