DZHK Paper of the month

Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9. DZHK-authors: Felix A. Trogisch, Aya Abouissa, Merve Keles, Gesine M. Dittrich, Julio Cordero, Steve Grein, Shruthi Hemanna, Luka Nicin, Sofia-Iris Bibli, Stefanie Dimmeler,...

Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure. DZHK-authors: Alessio Alogna, Uwe Primeßnig, Felix Hohendanner, Carsten Tschöpe, Burkert M. Pieske, Frank R. Heinzel. Journal of the American College of Cardiology 2024

In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector. DZHK authors: Patrick Laurette, Can Cao, Deepak Ramanujam, Lisa Weiss, Eileen Furlong, Flavia de Rezende, Stefan Engelhardt, Ralf Gilsbach, Circulation Research. 2024

High-Sensitivity Cardiac Troponin I Enhances Preeclampsia Prediction Beyond Maternal Factors and the sFlt-1/PlGF Ratio. DZHK-authors: Stefan Blankenberg, Tanja Zeller. Circulation, 2023.

Supervised exercise training in patients with advanced heart failure and left ventricular assist device: A multicentre randomized controlled trial (Ex-VAD trial). DZHK-authors: Anna Feuerstein, Felix Schönrath, Tim Friede, Marius Placzek, Doris Bach, Christoph Herrmann-Lingen,...

Cell-intrinsic effects of clonal hematopoiesis in heart failure. DZHK authors: Wesley T. Abplanalp, Sebastian Cremer, Maximilian Merten, Mariana Shumliakivska, Igor Macinkovic, Andreas M. Zeiher, David John & Stefanie Dimmeler, Nature Cardiovascular Research volume 2, pages...

Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. Magnussen et al., New England Journal of Medicine, 2023 Aug 26, DZHK authors: Christine Magnussen, Marcus Dörr, Anette Peters, Raphael Twerenbold, Philipp S. Wild, Andreas Ziegler, Stefan...

Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease. DZHK Autoren: Karin A. Ziegler, Anne Dueck, Dena Esfandyari, Pauline Pichler, Karolin Weber, Alexander Bartelt, Ludwig Weckbach, Steffen Massberg, Gabriele Schiatteralla, Stefan...

Cardiomuscular Biomarkers in the Diagnosis and Prognostication of Immune Checkpoint Inhibitor Myocarditis. DZHK authors: Lorenz H. Lehmann, Markus B. Heckmann, Daniel Finke, Frederic Stein, Jan Münster, Hugo A. Katus, Evangelos Giannitsis, Norbert Frey, Ziya Kaya. Circulation, 15...

The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. DZHK authors: Giorgia Ciliberti, Jedrzej Hoffmann, Andre Schneider, Stefan Guenther, Johannes Backs, Thomas Braun, Stefanie Dimmeler, Markus...