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The world's only clinical trial to implant artificial heart tissue in patients with heart failure to permanently strengthen the heart muscle has reached its first important milestone: the determination of the maximum safe dose could be completed after the treatment of 10...

Heart failure is one of the leading causes of death. Approximately one million people with heart failure also suffer from atrial fibrillation, a heart rhythm disorder that causes uncontrolled impulses in the atria and irregular heartbeats. This arrhythmia can usually be...

Cardiovascular disease is the leading cause of death in women and men worldwide. However, there are numerous differences between the hearts of the two sexes. The new junior research group of the German Center for Cardiovascular Research (DZHK) led by PD Dr. Claudia Crocini is...

It is a unique process in German health research: 20 experts and patients have worked together on a roadmap to systematically expand active patient participation in medical research.

A leaking mitral valve can be repaired surgically or with catheter-based techniques. A so-called mitral valve prolapse is particularly common, in which part of the valve protrudes (prolapses) into the left atrium. The American PRIMARY study investigates which method is most...

This is what ideal medicine would look like: Doctors could specifically alter molecular processes in diseased cells in the body and thus causally cure patients. This is the goal of the German Centers for Health Research (DZG) in the project "Cell type specific targeting for...

High blood pressure is the most common cause of stroke and heart attacks. Other organs, such as the kidneys or eyes can also suffer long-term damage if blood pressure is too high. However, patients have a good chance of bringing their high blood pressure back to normal and thus...

DZHK scientists in Mainz have confirmed this assumption in both mice and humans. If humans and animals were exposed to noise pollution in the past, a heart attack suffered later in life healed more poorly.

A team of researchers from the German Institute for Nutritional Research (DIfE) has shown in an 8-week pilot study that a diet rich in omega-3 fatty acids and proteins, combined with regular exercise, can have a positive effect on inflammation in older people. The results have...

Evolutionarily young miniproteins are unique in humans, and researchers have recently discovered thousands of them. Writing in Molecular Cell, Norbert Hübner and colleagues from the BIH and other institutions describe the origins of these tiny proteins and explain that they...