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An international, multi-centre study involving around 2500 patients is investigating the benefits and safety of optical coherence tomography (OCT) as an adjunct to angiography as a laser-based imaging modality for percutaneous coronary intervention (PCI). Prof. Dr. med. Ulf...

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Heart failure is already one of the leading causes of death. It affects around four million people in Germany, and the number is rising. In many cases, heart failure also causes abnormally high blood pressure in the lung vessels. This "pulmonary hypertension" in turn often...

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Heart attacks and strokes are diseases that kill millions of people every year. They are caused by the process of atherosclerosis, also known as arterial calcification. Macrophages play a particularly important role in the development of atherosclerosis in the walls of the blood...

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There has been a sharp increase worldwide in the use of mechanical, active cardiovascular support. The hope is that these devices will improve the chances of survival after the most severe form of acute heart failure, known as cardiogenic shock. A clinical study led by heart...

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Scientists of the Global Cardiovascular Risk Consortium under the auspices of the Department of Cardiology at the University Heart & Vascular Center of the Medical Center Hamburg-Eppendorf (UKE) and the German Center for Cardiovascular Research (DZHK) have proven that the five...

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The clinical trial NOAH – AFNET 6 conducted by the German Atrial Fibrillation Network (AFNET), Münster, Germany, revealed: In patients with atrial high rate episodes (AHRE), but without ECG-documented atrial fibrillation (AF), oral anticoagulation increases bleeding without...

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How do nerves and blood vessels interact in the ageing heart? Recent research findings from the Institute for Cardiovascular Regeneration and the Heart and Lung Institute at the Goethe University Frankfurt provide new insights into the ageing process of the heart. They have now...

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Overly active immune cells are often behind lung damage in diseases such as Covid-19. Researchers at the Technical University of Munich (TUM) have developed an RNA agent for a lung spray that slows the activity of these cells, known as macrophages. A new, sugar-based transport...

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The Cardiosurgical Research Group of the German Heart Centre at the Charité, led by Prof. Dr. Maximilian Emmert, presents the results of its MINOCA project in the renowned journal Circulation Research. They offer a novel simulation of myocardial infarction with non-obstructive...

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The biotechnology company AaviGen is providing €17 million in a second round of funding to advance precision gene therapies for heart failure into the clinic. In the context of cardiovascular translational research, the company emerged partly from DZHK-funded projects.

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