DZHK Paper of the month

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation. DZHK authors: Friederike Cuello, Umber Saleem, Malte Loos, Janice Raabe, Sandra Laufer, Bärbel M Ulmer, Ingke Braren, Norbert Hübner, Thomas Eschenhagen, Arne Hansen

Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients. nature communications 2021. DZHK authors: András Maifeld, Hendrik Bartolomaeus, Ulrike Löber, Ellen G. Avery, Lajos Markó, Nicola Wilck, Anja Mähler, Chia-Yu Chen, Ralf...

Epigenetic gene expression links heart failure to memory impairment. EMBO Mol Med (2021). DZHK authors: Anke Zieseniss, Dörthe Magdalena Katschinski, Karl Toischer, Andre Fischer

Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction. Nature Communications (2021). DZHK authors: Lukas S. Tombor, David John, Simone F. Glaser, Guillermo Luxán, Nina Baumgarten, Marcel H. Schulz, Janina Wittig,...

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Nat Commun 11, 5319 (2020). DZHK authors: Ferdinand le Noble, Rabea Hinkel, Christian Kupatt

Exercise-Stress Real-time Cardiac Magnetic Resonance Imaging for Non-Invasive Characterisation of Heart Failure with Preserved Ejection Fraction: The HFpEF Stress Trial. Circulation. 2021 Jan 21. DZHK authors: Sören J. Backhaus, Torben Lange, Elisabeth F. George, Kristian...

An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility. Circulation (2020), DZHK authors: Alexandra Madsen, Grit Höppner, Julia Krause, Marc N. Hirt, Sandra D. Laufer, Thomas Eschenhagen, Justus Stenzig

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study. European Heart Journal (2020), DZHK authors: David M...

Cells of the adult human heart. Nature 2020, DZHK authors: Henrike Maatz, Daniel Reichart, Barbara McDonough, Norbert Hübner

A Minimal-Invasive Approach for Standardized Induction of Myocardial Infarction in Mice. Circulation Research, DZHK authors: Florian Sicklinger, Yunhang Zhang, Lorenz Lehmann, Mathias H. Konstandin, Hugo A. Katus, Florian Leuschner