Study information

Recruiting status

Recruiting complete, follow-up continuing

Recruitment start





Clinical Trials Registration



Guideline relevant study

DZHK Funding

DZHK-assoziierte Studie (keine finanzielle Förderung)



Operative contact
Prof. Dr. Marc Dewey
Phone: 0049 30 450 527296
Email: dewey@charite.de

Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE)

The DZHK associated study DISCHARGE is investigating, whether cardiac computed tomography (CT) or cardiac catheterization is most appropriate for the evaluation of coronary artery disease in patients with stable chest pain.

DISCHARGE is a European collaborative project involving scientists from 31 research institutions in 18 European countries.

The study could influence current standards and guidelines and raise awareness of the efficacy and cost-effectiveness of cardiac CT among patients, providers, and decision makers in Europe.

The project is coordinated by Charité - Universitätsmedizin Berlin and funded by six million euros from the European Union.


Benedek T, Dewey M. et al.: Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease. Diabetes Care . 2023 Nov 1;46(11):2015-2023. doi: 10.2337/dc23-0710.

Mancone M., Dewey M. et al.: Impact of smoking in patients with suspected coronary artery disease in the randomised DISCHARGE trial. 2023 Nov 22. doi: 10.1007/s00330-023-10355-2.

All furhter publications of the trial can be found here.

Access cooperation for imaging data with the DZHK

Marc Dewey is also part of the DFG-funded GUIDE-IT (Guide to Data Sharing of Imaging Trials) project, which focuses on making medical imaging data from clinical trials more easily and specifically available for further research projects. Among other things, the DISCHARGE data are to be made accessible through this (contact: dewey@charite.de). A kick-off event was successfully held at the end of April 2023. For more information on GUIDE-IT, please click here.

Principal Investigators

Marc Dewey (Berlin)