Publications 2024
Here you will find the publications of the DZHK. Please also inform yourself about further publications on the websites of the research institutions involved in the DZHK.
To the DZHK Papers of the Month
July
Paper of the Month
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis
DZHK-Autor:innen: Florian Gaertner, Anne Dueck, Kami Pekayvaz, Christian Schulz, Konstantin Stark, Tobias Petzold, Stefan Engelhardt, Matthias Heinig, Steffen Massberg. Nature.
Atrial fibrillation burden: a new outcome predictor and therapeutic target. Becher, N., Metzner, A., Toennis, T., Kirchhof, P. & Schnabel, R. B. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38953776
Neuroimmune crosstalk : How mental stress fuels vascular inflammation. Meyer-Lindemann, U. & Sager, H. B. Herz (2024). https://www.ncbi.nlm.nih.gov/pubmed/38954012
Estimated Annual Healthcare Costs After Acute Pulmonary Embolism: Results From a Prospective Multicentre Cohort Study. Mohr, K., Mildenberger, P., Neusius, T., Christodoulou, K. C., Farmakis, I. T., Kaier, K., Barco, S., Klok, F. A., Hobohm, L., Keller, K., Becker, D., Abele, C., Bruch, L., Ewert, R., Schmidtmann, I., Wild, P. S., Rosenkranz, S., Konstantinides, S. V., Binder, H. & Valerio, L. Eur Heart J Qual Care Clin Outcomes (2024). https://www.ncbi.nlm.nih.gov/pubmed/38950900
Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: the KORA study. Raeisi-Dehkordi, H., Amiri, M., Rathmann, W., Zeller, T., Adamski, J., Bano, A., van der Schouw, Y. T., Thorand, B., Muka, T. & Nano, J. Eur J Epidemiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38954350
Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Trastulla, L., Dolgalev, G., Moser, S., Jimenez-Barron, L. T., Andlauer, T. F. M., von Scheidt, M., Schizophrenia Working Group of the Psychiatric Genomics, C., Budde, M., Heilbronner, U., Papiol, S., Teumer, A., Homuth, G., Volzke, H., Dorr, M., Falkai, P., Schulze, T. G., Gagneur, J., Iorio, F., Muller-Myhsok, B., Schunkert, H. & Ziller, M. J. Nat Commun 15, 5534 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38951512
App-Based Addiction Prevention at German Vocational Schools: Implementation and Reach for a Cluster-Randomized Controlled Trial. Guertler, D., Blasing, D., Moehring, A., Meyer, C., Brandt, D., Schmidt, H., Rehbein, F., Neumann, M., Dreissigacker, A., Bischof, A., Bischof, G., Surig, S., Hohls, L., Hagspiel, M., Wurm, S., Haug, S. & Rumpf, H. J. Prev Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/38958917
Incidence and Outcomes of Emergency Intraprocedural Surgical Conversion During Transcatheter Aortic Valve Implantation: A Multicentric Analysis. Marin-Cuartas, M., de Waha, S., de la Cuesta, M., Deo, S. V., Kaminski, A., Fach, A., Meyer, A. L., Popov, A. F., Hagl, C., Joskowiak, D., Kuhn, E. W., Ius, F., Leuschner, F., Awad, G., Thiele, H., Abdalla, A., Garbade, J., Ender, J., Wehrmann, K., Eghbalzadeh, K., Vitanova, K., Conradi, L., Diab, M., Franz, M., Geyer, M., Meineri, M., Misfeld, M., Abdel-Wahab, M., Bhadra, O. D., Osteresch, R., Sandoval Boburg, R., Lange, R., Leontyev, S., Saha, S., Desch, S., Lehmann, S., Noack, T., Doenst, T., Borger, M. A. & Kiefer, P. J Am Heart Assoc 13, e033964 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38958140
Pulmonary vein reconnection and repeat ablation characteristics following cryoballoon-compared to radiofrequency-based pulmonary vein isolation. Obergassel, J., Nies, M., Taraba, S., Rottner, L., Lemoine, M. D., My, I., Moser, F., Riess, J. L., Schenker, N., Dinshaw, L., Schleberger, R., Reissmann, B., Meyer, C., Willems, S., Rillig, A., Kirchhof, P. & Metzner, A. J Cardiovasc Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38956821
The effect of high-dose selenium on mortality and postoperative organ dysfunction in post-cardiotomy cardiogenic shock patients supported with mechanical circulatory support - A post-hoc analysis of the SUSTAIN CSX trial. Ott, S., Dresen, E., Lee, Z. Y., Muller-Wirtz, L. M., Procopiuc, L., Ekrami, E., Pitts, L., Hellner, N., Catena, D., Duerr, G. D., Wittmann, M., Waeschle, R. M., Elke, G., O'Brien, B., Heyland, D. K. & Stoppe, C. J Crit Care 83, 154853 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38955117
Evaluation of frailty in geriatric patients undergoing cardiac rehabilitation after cardiac procedure: results of a prospective, cross-sectional study. Steinmetz, C., Krause, L., Sulejmanovic, S., Kaumkotter, S., Hartog, J., Scheenstra, B., Stefan, F., Mengden, T., Grefe, C., Knoglinger, E., Reiss, N., Bjarnason-Wehrens, B., Schmidt, T., Sadlonova, M., von Arnim, C. A. F. & Heinemann, S. BMC Sports Sci Med Rehabil 16, 146 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38956610
Impact of Lipoprotein(a) Level on Low-Density Lipoprotein Cholesterol- or Apolipoprotein B-Related Risk of Coronary Heart Disease. Arnold, N., Blaum, C., Gossling, A., Brunner, F. J., Bay, B., Zeller, T., Ferrario, M. M., Brambilla, P., Cesana, G., Leoni, V., Palmieri, L., Donfrancesco, C., Ojeda, F., Linneberg, A., Soderberg, S., Iacoviello, L., Gianfagna, F., Costanzo, S., Sans, S., Veronesi, G., Thorand, B., Peters, A., Tunstall-Pedoe, H., Kee, F., Salomaa, V., Schnabel, R. B., Kuulasmaa, K., Blankenberg, S., Waldeyer, C., Koenig, W. & BiomarCa, R. E. I. J Am Coll Cardiol 84, 165-177 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38960510
[Oral anticoagulation with Edoxaban for stroke prevention in patients with atrial fibrillation: Analysis of 1-year follow-up data of routine clinical practice in Germany, Austria and Switzerland (DACH) from the ETNA-AF registry]. Dinshaw, L., Steffel, J., Gotte, A., Weiss, T. W., Waltenberger, J. & Kirchhof, P. Dtsch Med Wochenschr 149, e58-e66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38959945
Imaging of Existing and Newly Translated Proteins Elucidates Mechanisms of Sarcomere Turnover. Douvdevany, G., Erlich, I., Haimovich-Caspi, L., Mashiah, T., Prondzynski, M., Pricolo, M. R., Alegre-Cebollada, J., Linke, W. A., Carrier, L. & Kehat, I. Circ Res135, 474-487 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38962864
Impact of sex on clinical outcome in early Multiple Sclerosis. Gottwald, N. S., Asseyer, S., Chien, C., Brasanac, J., Nauman, A. T., Rust, R., Schmitz-Hubsch, T., Strobl, J. B., Ruprecht, K., Paul, F., Regitz-Zagrosek, V., Gold, S. M. & Sperber, P. S. Mult Scler Relat Disord 88, 105749 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38959589
Sex-dependent differences in macaque brain mitochondria. Guerrero, I., Yoval-Sanchez, B., Konrad, C., Manfredi, G., Wittig, I. & Galkin, A. Biochim Biophys Acta Bioenerg 1865, 149494 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38960079
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE(-/-) mice. Bruckner, A., Brandtner, A., Rieck, S., Matthey, M., Geisen, C., Fels, B., Stei, M., Kusche-Vihrog, K., Fleischmann, B. K. & Wenzel, D. Angiogenesis (2024). https://www.ncbi.nlm.nih.gov/pubmed/38965173
Gut dysbiosis contributes to TMAO accumulation in CKD. Holle, J., McParland, V., Anandakumar, H., Gerritzmann, F., Behrens, F., Schumacher, F., Thumfart, J., Eckardt, K. U., Kleuser, B., Bartolomaeus, H. & Wilck, N. Nephrol Dial Transplant (2024). https://www.ncbi.nlm.nih.gov/pubmed/38964836
Is an accurate self-perceived health risk beneficial for patients to minimize prehospital delay time at onset of a ST-segment elevated myocardial infarction (STEMI)? Ladwig, K. H., Olliges, E., Albarqouni, L., Hoschar, S., Ma, W. & Fang, X. Herz 49, 270-276 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38965126
Infective endocarditis and spondylodiscitis-impact of sequence of surgical therapy on survival and recurrence rate. Weber, C., Misfeld, M., Diab, M., Saha, S., Elderia, A., Marin-Cuartas, M., Luehr, M., Yagdiran, A., Eysel, P., Jung, N., Hagl, C., Doenst, T., Borger, M. A., Kernich, N. & Wahlers, T. Eur J Cardiothorac Surg 66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38964339
Atavism as a cause of dilative cardiomyopathy. Fastenrath, F., Tavakoli, A., Duerschmied, D., Haghi, D., Ayx, I. & Papavassiliu, T. Hellenic J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38969174
Editorial to: Extensive ablation for persistent atrial fibrillation patients with mitral regurgitation: Insights from the EARNEST-PVI prospective randomized trial. Heeger, C. H. & Alagjozovski, H. Int J Cardiol 412, 132299 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38968973
Advances in nucleic acid-targeted therapies for cardiovascular disease prevention. Makhmudova, U., Steinhagen-Thiessen, E., Volpe, M. & Landmesser, U. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38970537
The impact of onset-to-cut time in surgery for stable acute type a aortic dissection-a single-center retrospective cohort study. Pitts, L., Kofler, M., Montagner, M., Heck, R., Dominik Kurz, S., Claudiu Paun, A., Falk, V. & Kempfert, J. Interdiscip Cardiovasc Thorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38970376
Effects of baroreflex activation therapy on cardiac function and morphology. Schafer, A. C., Wallbach, M., Schroer, C., Lehnig, L. Y., Luders, S., Hasenfuss, G., Wachter, R. & Koziolek, M. J. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38970313
Reduced dynamic changes in pulmonary artery compliance during isometric handgrip exercise in patients with heart failure. Hashemi, D., Hou, X., Doeblin, P., Weiss, J., Beyer, R., Neye, M., Erley, J., Bucius, P., Tanacli, R., Kuehne, T., Kelm, M., Blum, M., Edelmann, F., Kuebler, W. M., Dungen, H. D., Schuster, A., Stoiber, L. & Kelle, S. Sci Rep 14, 15594 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38971904
A multicenter study of asymmetric and symmetric dimethylarginine as predictors of mortality risk in hospitalized COVID-19 patients. Hannemann, J., Zink, A., Mileva, Y., Balfanz, P., Dahl, E., Volland, S., Illig, T., Schwedhelm, E., Kurth, F., Stege, A., Aepfelbacher, M., Hoffmann, A. & Boger, R. Sci Rep 14, 15739 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38977837
Right ventricular strain to systolic pulmonary artery pressure ratio in response to treatment of pulmonary arterial hypertension. Pott, J., Csengeri, D., Ostermann, J., Klose, H., Sinning, C. & Harbaum, L. ERJ Open Res 10 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38978554
Quantitative flow ratio or angiography for the assessment of non-culprit lesions in acute coronary syndromes, a randomized trial. Ullrich-Daub, H., Olschewski, M., Schnorbus, B., Belhady, A., Kohler, T., Vosseler, M., Munzel, T. & Gori, T. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38980329
Associations between adrenal gland volume and adipose tissue compartments - a whole body MRI study. Askani, E., Rospleszcz, S., Lorbeer, R., Wintergerst, C., Muller-Peltzer, K., Kiefer, L. S., Kellner, E., Reisert, M., Rathmann, W., Peters, A., Schlett, C. L., Bamberg, F. & Storz, C. Nutr Metab (Lond) 21, 45 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38982517
The oral microbiome is associated with HPA axis response to a psychosocial stressor. Charalambous, E. G., Meriaux, S. B., Guebels, P., Muller, C. P., Leenen, F. A. D., Elwenspoek, M. M. C., Thiele, I., Hertel, J. & Turner, J. D. Sci Rep 14, 15841 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38982178
Predictors of ventricular tachyarrhythmia in patients with a wearable cardioverter defibrillator: an international multicenter registry. Kreimer, F., Koepsel, K., Gotzmann, M., Kovacs, B., Dreher, T. C., Blockhaus, C., Klein, N., Kuntz, T., Shin, D. I., Lapp, H., Rosenkaimer, S., Abumayyaleh, M., Hamdani, N., Saguner, A. M., Erath, J. W., Duru, F., Beiert, T., Schiedat, F., Weth, C., Custodis, F., Akin, I., Mugge, A., Aweimer, A. & El-Battrawy, I. J Interv Card Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38985244
Nexilin in cardiomyopathy: unveiling its diverse roles with special focus on endocardial fibroelastosis. Rahimzadeh, M., Tennstedt, S. & Aherrahrou, Z. Heart Fail Rev (2024). https://www.ncbi.nlm.nih.gov/pubmed/38985384
Clinical impact of novel CMR technology on patients with congenital heart disease. A scientific statement of the Association for European Pediatric and Congenital Cardiology (AEPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC. Voges, I., Raimondi, F., McMahon, C. J., Ait-Ali, L., Babu-Narayan, S. V., Botnar, R. M., Burkhardt, B., Gabbert, D. D., Grosse-Wortmann, L., Hasan, H., Hansmann, G., Helbing, W. A., Krupickova, S., Latus, H., Martini, N., Martins, D., Muthurangu, V., Ojala, T., van Ooij, P., Pushparajah, K., Rodriguez-Palomares, J., Sarikouch, S., Grotenhuis, H. B. & Greil, F. G. Eur Heart J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38985851
Serum Concentrations of Matrix Metalloproteinase-1 and Procollagen Type I Carboxy Terminal Propeptide Discriminate Infarct-Like Myocarditis and Non-ST-Segment-Elevation Myocardial Infarction. Bacmeister, L., Cavus, E., Bohnen, S., Tahir, E., Wolf, H., Buellesbach, A., Heidenreich, A., Haacke, V. K., Weber, S., Hilgendorf, I., Zeller, T., Ojeda, F., Radunski, U. K., Lund, G. K., Adam, G., Blankenberg, S., Westermann, D., Muellerleile, K. & Lindner, D. J Am Heart Assoc 13, e034194 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38989835
Biostatistical Aspects of Whole Genome Sequencing Studies: Preprocessing and Quality Control. Betschart, R. O., Riccio, C., Aguilera-Garcia, D., Blankenberg, S., Guo, L., Moch, H., Seidl, D., Solleder, H., Thalen, F., Thiery, A., Twerenbold, R., Zeller, T., Zoche, M. & Ziegler, A. Biom J 66, e202300278 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38988195
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis. Gaertner, F., Ishikawa-Ankerhold, H., Stutte, S., Fu, W., Weitz, J., Dueck, A., Nelakuditi, B., Fumagalli, V., van den Heuvel, D., Belz, L., Sobirova, G., Zhang, Z., Titova, A., Navarro, A. M., Pekayvaz, K., Lorenz, M., von Baumgarten, L., Kranich, J., Straub, T., Popper, B., Zheden, V., Kaufmann, W. A., Guo, C., Piontek, G., von Stillfried, S., Boor, P., Colonna, M., Clauss, S., Schulz, C., Brocker, T., Walzog, B., Scheiermann, C., Aird, W. C., Nerlov, C., Stark, K., Petzold, T., Engelhardt, S., Sixt, M., Hauschild, R., Rudelius, M., Oostendorp, R. A. J., Iannacone, M., Heinig, M. & Massberg, S. Nature 631, 645-653 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38987596
Incidence and impact of venous thromboembolism in hospitalized patients with acute pancreatitis. Keller, K., Sivanathan, V., Farmakis, I. T., Schmitt, V. H., Espinola-Klein, C., Schmidt, F. P., Munzel, T., Konstantinides, S. & Hobohm, L. Dig Liver Dis (2024). https://www.ncbi.nlm.nih.gov/pubmed/38987040
Impact of Intraprocedural Mitral Regurgitation and Gradient Following Transcatheter Edge-to-Edge Repair for Primary Mitral Regurgitation. Ludwig, S., Koell, B., Weimann, J., Donal, E., Patel, D., Stolz, L., Tanaka, T., Scotti, A., Trenkwalder, T., Rudolph, F., Samim, D., von Stein, P., Giannini, C., Dreyfus, J., Paradis, J. M., Adamo, M., Karam, N., Bohbot, Y., Bernard, A., Melica, B., Quagliana, A., Lavie Badie, Y., Kessler, M., Chehab, O., Redwood, S., Lubos, E., Sondergaard, L., Metra, M., Primerano, C., Iliadis, C., Praz, F., Gercek, M., Xhepa, E., Nickenig, G., Latib, A., Schofer, N., Makkar, R., Granada, J. F., Modine, T., Hausleiter, J., Kalbacher, D., Coisne, A. & Investigators, P.-M. JACC Cardiovasc Interv 17, 1559-1573 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38986655
The reactive pyruvate metabolite dimethylglyoxal mediates neurological consequences of diabetes. Rhein, S., Costalunga, R., Inderhees, J., Gurtzgen, T., Faupel, T. C., Shaheryar, Z., Arrulo Pereira, A., Othman, A., Begemann, K., Binder, S., Stolting, I., Dorta, V., Nawroth, P. P., Fleming, T., Oexle, K., Prevot, V., Nogueiras, R., Meyhofer, S., Meyhofer, S. M. & Schwaninger, M. Nat Commun 15, 5745 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38987239
Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C collaborative meta-analysis of randomised controlled trials. Apperloo, E. M., Neuen, B. L., Fletcher, R. A., Jongs, N., Anker, S. D., Bhatt, D. L., Butler, J., Cherney, D. Z. I., Herrington, W. G., Inzucchi, S. E., Jardine, M. J., Liu, C. C., Mahaffey, K. W., McGuire, D. K., McMurray, J. J. V., Neal, B., Packer, M., Perkovic, V., Sabatine, M. S., Solomon, S. D., Staplin, N., Szarek, M., Vaduganathan, M., Wanner, C., Wheeler, D. C., Wiviott, S. D., Zannad, F. & Heerspink, H. J. L. Lancet Diabetes Endocrinol 12, 545-557 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38991584
Treatment of sleep apnoea early after myocardial infarction with adaptive servo-ventilation - a proof-of-concept randomised controlled trial. Arzt, M., Fox, H., Stadler, S., Hetzenecker, A., Oldenburg, O., Hamer, O. W., Poschenrieder, F., Wiest, C., Tanacli, R., Kelle, S., Bruch, L., Seidel, M., Koller, M., Zeman, F., Buchner, S. & Investigators, T.-A. I. Eur Respir J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38991707
Effect of empagliflozin on total myocardial infarction events by type and additional coronary outcomes: insights from the randomized EMPA-REG OUTCOME trial. Fitchett, D., Zinman, B., Inzucchi, S. E., Wanner, C., Anker, S. D., Pocock, S., Mattheus, M., Vedin, O. & Lund, S. S. Cardiovasc Diabetol 23, 248 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38992713
Interpretation of elevated baseline concentrations and serial changes of high-sensitivity cardiac troponin T in confirmed muscular dystrophies. Yildirim, M., Reich, C., Salbach, C., Pribe-Wolferts, R., Milles, B. R., Tager, T., Mueller-Hennessen, M., Weiler, M., Meder, B., Frey, N. & Giannitsis, E. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38992971
CD74 is a functional MIF receptor on activated CD4(+) T cells. Zhang, L., Woltering, I., Holzner, M., Brandhofer, M., Schaefer, C. C., Bushati, G., Ebert, S., Yang, B., Muenchhoff, M., Hellmuth, J. C., Scherer, C., Wichmann, C., Effinger, D., Hubner, M., El Bounkari, O., Scheiermann, P., Bernhagen, J. & Hoffmann, A. Cell Mol Life Sci 81, 296 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38992165
A Novel C3/C4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction. Potlitz, F., Palm, G. J., Bodtke, A., Lammers, M., Schade, D. & Link, A. Molecules 29 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38999014
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome. Busley, A. V., Gutierrez-Gutierrez, O., Hammer, E., Koitka, F., Mirzaiebadizi, A., Steinegger, M., Pape, C., Bohmer, L., Schroeder, H., Kleinsorge, M., Engler, M., Cirstea, I. C., Gremer, L., Willbold, D., Altmuller, J., Marbach, F., Hasenfuss, G., Zimmermann, W. H., Ahmadian, M. R., Wollnik, B. & Cyganek, L. Cell Rep43, 114448 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39003740
Clinical outcomes and predictors of transapical transcatheter mitral valve replacement: the Tendyne Expanded Clinical Study. Conradi, L., Ludwig, S., Sorajja, P., Duncan, A., Bethea, B., Dahle, G., Babaliaros, V., Guerrero, M., Thourani, V., Dumonteil, N., Modine, T., Garatti, A., Denti, P., Leipsic, J., Chuang, M. L., Blanke, P., Muller, D. W. & Badhwar, V. EuroIntervention 20, e887-e897 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39007829
Novel Long Noncoding RNA HEAT4 Affects Monocyte Subtypes, Reducing Inflammation and Promoting Vascular Healing. Kneuer, J. M., Grajek, I. A., Winkler, M., Erbe, S., Meinecke, T., Weiss, R., Garfias-Veitl, T., Sheikh, B. N., Konig, A. C., Mobius-Winkler, M. N., Kogel, A., Kresoja, K. P., Rosch, S., Kokot, K. E., Filipova, V., Gaul, S., Thiele, H., Lurz, P., von Haehling, S., Speer, T., Laufs, U. & Boeckel, J. N. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39005211
Renal protection after hemorrhagic shock in rats: Possible involvement of SUMOylation. Oliveira, F., Sousa Soares, E., Pillmann Ramos, H., Lattig-Tunnemann, G., Harms, C., Cimarosti, H. & Sordi, R. Biochem Pharmacol 227, 116425 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39004233
Learning carotid vessel wall segmentation in black-blood MRI using sparsely sampled cross-sections from 3D data. Rahlfs, H., Hullebrand, M., Schmitter, S., Strecker, C., Harloff, A. & Hennemuth, A. J Med Imaging (Bellingham) 11, 044503 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39006308
Simple but useful: DI in the assessment of patients with aortic stenosis. Schneider-Reigbert, M. & Dreger, H. Echocardiography 41, e15889 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39008001
TAVI in moderate aortic stenosis: the earlier the better? Schofer, N. & Ludwig, S. EuroIntervention20, e840-e842 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39007827
Loss of Y Chromosome and Cardiovascular Events in Chronic Kidney Disease. Weyrich, M., Cremer, S., Gerster, M., Sarakpi, T., Rasper, T., Zewinger, S., Patyna, S. R., Leistner, D. M., Heine, G. H., Wanner, C., Marz, W., Fliser, D., Dimmeler, S., Zeiher, A. M. & Speer, T. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39005209
Cardiac wasting and cancer. Anker, M. S., Rassaf, T., Zamorano, J. L., Khan, M. S. & Landmesser, U. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39011778
Left Atrial Roof Enlargement Is a Distinct Feature of Heart Failure With Preserved Ejection Fraction. Backhaus, S. J., Nasopoulou, A., Lange, T., Schulz, A., Evertz, R., Kowallick, J. T., Hasenfuss, G., Lamata, P. & Schuster, A. Circ Cardiovasc Imaging17, e016424 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39012942
Quantitative assessment of cardiac (123)iodo-metaiodobenzylguanidine SPECT/CT in patients with arrhythmogenic right ventricular cardiomyopathy: novel insight in disease monitoring. Hagen, J. M., Zacherl, M. J., Brendel, M., Clauss, S., Kaab, S., Bartenstein, P., Todica, A., Boening, G. & Fischer, M. J Nucl Cardiol, 101911 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009215
Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy. Paulke, N. J., Fleischhacker, C., Wegener, J. B., Riedemann, G. C., Cretu, C., Mushtaq, M., Zaremba, N., Mobius, W., Zuhlke, Y., Wedemeyer, J., Liebmann, L., Gorshkova, A. A., Kownatzki-Danger, D., Wagner, E., Kohl, T., Wichmann, C., Jahn, O., Urlaub, H., Toischer, K., Hasenfuss, G., Moser, T., Preobraschenski, J., Lenz, C., Rog-Zielinska, E. A., Lehnart, S. E. & Brandenburg, S. Circ Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39011635
RhoA-mediated G(12)-G(13) signaling maintains muscle stem cell quiescence and prevents stem cell loss. Peng, Y., Du, J., Li, R., Gunther, S., Wettschureck, N., Offermanns, S., Wang, Y., Schneider, A. & Braun, T. Cell Discov 10, 76 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009565
LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome. Pozojevic, J., Sivaprasad, R., Lass, J., Haarich, F., Trinh, J., Kakar, N., Schulz, K., Handler, K., Verrijn Stuart, A. A., Giltay, J. C., van Gassen, K. L., Caliebe, A., Holterhus, P. M., Spielmann, M. & Hornig, N. C. Sci Rep 14, 16302 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009627
Personalized care in dilated cardiomyopathy: Rationale and study design of the activeDCM trial. Sedaghat-Hamedani, F., Amr, A., Betz, T., Kayvanpour, E., Reich, C., Wettstein, R., Heinze, O., Mohr, I., Krisam, R., Sander, A., Klose, C., Friedmann-Bette, B., Frey, N. & Meder, B. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39010317
Influence of AAV vector tropism on long-term expression and Fc-gamma receptor binding of an antibody targeting SARS-CoV-2. Wagner, J. T., Muller-Schmucker, S. M., Wang, W., Arnold, P., Uhlig, N., Issmail, L., Eberlein, V., Damm, D., Roshanbinfar, K., Ensser, A., Oltmanns, F., Peter, A. S., Temchura, V., Schrodel, S., Engel, F. B., Thirion, C., Grunwald, T., Wuhrer, M., Grimm, D. & Uberla, K. Commun Biol 7, 865 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009807
When size matters: A novel compact Cas12a variant for in vivo genome editing. Bubeck, F. & Grimm, D. PLoS Biol 22, e3002637 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39018342
Prediction of Left Ventricle Pressure Indices Via a Machine Learning Approach Combining ECG, Pulse Oximetry, and Cardiac Sounds: a Preclinical Feasibility Study. Fassina, L., Muzio, F. P. L., Berboth, L., Otvos, J., Faragli, A. & Alogna, A. J Cardiovasc Transl Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39017912
Myeloid cell-derived interleukin-6 induces vascular dysfunction and vascular and systemic inflammation. Knopp, T., Jung, R., Wild, J., Bochenek, M. L., Efentakis, P., Lehmann, A., Bieler, T., Garlapati, V., Richter, C., Molitor, M., Perius, K., Finger, S., Lagrange, J., Ghasemi, I., Zifkos, K., Kommoss, K. S., Masri, J., Reissig, S., Randriamboavonjy, V., Wunderlich, T., Hovelmeyer, N., Weber, A. N. R., Mufazalov, I. A., Bosmann, M., Bechmann, I., Fleming, I., Oelze, M., Daiber, A., Munzel, T., Schafer, K., Wenzel, P., Waisman, A. & Karbach, S. Eur Heart J Open 4, oeae046 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39015379
[Cardiac irradiation for improvement of left ventricular function]. Mehrhof, F., Hohendanner, F., Blanck, O., Hindricks, G., Zips, D. & Hausmann, F. Strahlenther Onkol 200, 847-849 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39017687
TAVR-in-TAVR in a Patient With a 12-Year-Old Chimney Stent: The Inverted Culotte Double Chimney Technique. Dreger, H., Al Harbi, A. S., Geyer, T., Dushe, S., Sundermann, S. H., Unbehaun, A. & Spethmann, S. JACC Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39023449
Improved Detection of Small and Low-Density Plaques in Virtual Noncontrast Imaging-based Calcium Scoring at Photon-Counting Detector CT. Fink, N., Emrich, T., Schoepf, U. J., Zsarnoczay, E., O'Doherty, J., Halfmann, M. C., Griffith, J. P., 3rd, Pinos, D., Suranyi, P., Baruah, D., Kabakus, I. M., Ricke, J. & Varga-Szemes, A. Radiol Cardiothorac Imaging 6, e230328 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39023373
Transportation Model for Acute Aortic Dissection: Implications for Reduced Treatment Centers. Goehlich, A., Prasse, P., Zaschke, L., Habazettl, H., Falk, V. & Kurz, S. D. Eur J Cardiothorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39024021
A case report of a malignant melanoma in the cardiologic diagnostic workup. Jahnke, C., Gramlich, R., Sander, C., Willems, S. & Chung, D. U. Eur Heart J Case Rep 8, ytae312 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39021359
Catheter-based ablation to improve outcomes in patients with atrial fibrillation and heart failure with preserved ejection fraction: Rationale and design of the CABA-HFPEF-DZHK27 trial. Parwani, A. S., Kaab, S., Friede, T., Tilz, R. R., Bauersachs, J., Frey, N., Hindricks, G., Lewalter, T., Rienstra, M., Rillig, A., Scherr, D., Steven, D., Kirchhof, P. & Pieske, B. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39023141
Endothelin-1 influences mechanical properties and contractility of hiPSC derived cardiomyocytes resulting in diastolic dysfunction. Redwanz, C., Pires, R. H., Biedenweg, D., Gross, S., Otto, O. & Konemann, S. J Mol Cell Cardiol 194, 105-117 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39019395
Ventricular unloading causes prolongation of the QT interval and induces ventricular arrhythmias in rat hearts. Schwoerer, A. P., Biermann, D. & Ehmke, H. Front Physiol 15, 1346093 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39022307
Chaos control in cardiac dynamics: terminating chaotic states with local minima pacing. Suth, D., Luther, S. & Lilienkamp, T. Front Netw Physiol 4, 1401661 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39022296
Split intein-mediated protein trans-splicing to express large dystrophins. Tasfaout, H., Halbert, C. L., McMillen, T. S., Allen, J. M., Reyes, T. R., Flint, G. V., Grimm, D., Hauschka, S. D., Regnier, M. & Chamberlain, J. S. Nature (2024). https://www.ncbi.nlm.nih.gov/pubmed/39020181
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Widjaja, A. A., Lim, W. W., Viswanathan, S., Chothani, S., Corden, B., Dasan, C. M., Goh, J. W. T., Lim, R., Singh, B. K., Tan, J., Pua, C. J., Lim, S. Y., Adami, E., Schafer, S., George, B. L., Sweeney, M., Xie, C., Tripathi, M., Sims, N. A., Hubner, N., Petretto, E., Withers, D. J., Ho, L., Gil, J., Carling, D. & Cook, S. A. Nature (2024). https://www.ncbi.nlm.nih.gov/pubmed/39020175
Cost-effectiveness of applying high-sensitivity troponin I to a score for cardiovascular risk prediction in asymptomatic population. Julicher, P., Makarova, N., Ojeda, F., Giusepi, I., Peters, A., Thorand, B., Cesana, G., Jorgensen, T., Linneberg, A., Salomaa, V., Iacoviello, L., Costanzo, S., Soderberg, S., Kee, F., Giampaoli, S., Palmieri, L., Donfrancesco, C., Zeller, T., Kuulasmaa, K., Tuovinen, T., Lamrock, F., Conrads-Frank, A., Brambilla, P., Blankenberg, S. & Siebert, U. PLoS One 19, e0307468 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028718
Genetic testing in early-onset atrial fibrillation. Kany, S., Jurgens, S. J., Ramo, J. T., Christophersen, I. E., Rienstra, M., Chung, M. K., Olesen, M. S., Ackerman, M. J., McNally, E. M., Semsarian, C., Schnabel, R. B., Wilde, A. A. M., Benjamin, E. J., Rehm, H. L., Kirchhof, P., Bezzina, C. R., Roden, D. M., Shoemaker, M. B. & Ellinor, P. T. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028637
Left atrial appendage closure for stroke prevention in atrial fibrillation: current status and perspectives. Landmesser, U., Skurk, C., Tzikas, A., Falk, V., Reddy, V. Y. & Windecker, S. Eur Heart J 45, 2914-2932 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39027946
Effect of inferior caval valve implantation on circulating immune cells and inflammatory mediators in severe tricuspid regurgitation. Mattig, I., Hewing, B., Knebel, F., Meisel, C., Ludwig, A., Konietschke, F., Stangl, V., Stangl, K., Laule, M. & Dreger, H. BMC Cardiovasc Disord 24, 373 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39026154
Association of aortic diameters and mortality in the general population-an MRI-based study. Mensel, B., Mahnken, A. H., Kaiser, E., Volzke, H., Dorr, M., Felix, S. B., Ittermann, T., Lieb, W. & Lorbeer, R. Eur Radiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39026062
Gene expression networks in endothelial cells from failing human hearts. Wirth, L., Erny, E., Krane, M., Lahm, H., Hein, L., Gilsbach, R. & Lother, A. Am J Physiol Heart Circ Physiol 327, H573-H581 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028282
Trophoblast Side-Population Markers are Dysregulated in Preeclampsia and Fetal Growth Restriction. Wong, G. P., Hartmann, S., Simmons, D. G., Ellis, S., Nonn, O., Cannon, P., Nguyen, T. V., Nguyen, A., Bartho, L. A., Tong, S., Hannan, N. J. & Kaitu'u-Lino, T. J. Stem Cell Rev Rep (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028417
Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A ten-year retrospective study in a German tertiary care hospital. Yu, Y., Lettow, I., Roedl, K., Jarczak, D., Pinnschmidt, H., Reichenspurner, H., Bernhardt, A. M., Soffker, G., Schrage, B., Haar, M., Weber, T., Frings, D., Kluge, S. & Fischer, M. J Crit Care84, 154880 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39024824
Machine learning for catalysing the integration of noncoding RNA in research and clinical practice. de Gonzalo-Calvo, D., Karaduzovic-Hadziabdic, K., Dalgaard, L. T., Dieterich, C., Perez-Pons, M., Hatzigeorgiou, A., Devaux, Y. & Kararigas, G. EBioMedicine 106, 105247 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39029428
Increased expression of human endogenous retrovirus K in endomyocardial biopsies from patients with cardiomyopathy - a transcriptomics meta-analysis. Heckmann, M. B., Finke, D., Sauerbrey, L., Frey, N. & Lehmann, L. H. BMC Genomics 25, 707 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39033293
Prognostic impact of quantitative flow ratio (QFR)-consistent complete revascularization in patients with myocardial infarction and multivessel coronary artery disease. Erbay, A., Penzel, L., Abdelwahed, Y. S., Heuberger, A., Schatz, A. S., Seppelt, C., Schlender, L. S., Steiner, J., Haghikia, A., Steven, S., Landmesser, U., Stahli, B. E. & Leistner, D. M. Am Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39033995
Effects of Oral Butyrate on Blood Pressure in Patients With Hypertension: A Randomized, Placebo-Controlled Trial. Verhaar, B. J. H., Wijdeveld, M., Wortelboer, K., Rampanelli, E., Levels, J. H. M., Collard, D., Cammenga, M., Nageswaran, V., Haghikia, A., Landmesser, U., Li, X. S., DiDonato, J. A., Hazen, S. L., Garrelds, I. M., Danser, A. H. J., van den Born, B. H., Nieuwdorp, M. & Muller, M. Hypertension (2024). https://www.ncbi.nlm.nih.gov/pubmed/39034917
Cross-species single-cell RNA sequencing reveals divergent phenotypes and activation states of adaptive immunity in human carotid and experimental murine atherosclerosis. Horstmann, H., Michel, N. A., Sheng, X., Hansen, S., Lindau, A., Pfeil, K., Fernandez, M. C., Marchini, T., Winkels, H., Mitre, L. S., Abogunloko, T., Li, X., Mwinyella, T. B., Gissler, M. C., Bugger, H., Heidt, T., Buscher, K., Hilgendorf, I., Stachon, P., Piepenburg, S., Verheyen, N., Rathner, T., Gerhardt, T., Siegel, P. M., Oswald, W. K., Cohnert, T., Zernecke, A., Madl, J., Kohl, P., Foks, A. C., von Zur Muehlen, C., Westermann, D., Zirlik, A. & Wolf, D. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39041203
Calcium-activated potassium channels as amplifiers of TRPV4-mediated pulmonary edema formation in male mice. Li, M., Roeder, J., Blazquez-Prieto, J., Schulz, S., Naujox, J., Falivene, J., Erfinanda, L., Liedtke, W., Albaiceta, G. M., Kuebler, W. M. & Michalick, L. Anesthesiology (2024). https://www.ncbi.nlm.nih.gov/pubmed/39042042
Evaluation of cell survival in different 3D-printed geometric shapes of human iPSC-derived engineered heart tissue. Yildirim, Y., Degener, L., Reuter, L., Petersen, J., Gabel, L., Sommer, A., Pahrmann, C., Reichenspurner, H. & Pecha, S. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/39041632
Introducing Attribute Association Graphs to Facilitate Medical Data Exploration: Development and Evaluation Using Epidemiological Study Data. Bellmann, L., Wiederhold, A. J., Trube, L., Twerenbold, R., Uckert, F. & Gottfried, K. JMIR Med Inform12, e49865 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39046780
Heparin-Induced Thrombocytopenia in Patients Suffering Cardiogenic Shock. Lusebrink, E., Lanz, H., Binzenhofer, L., Hoffmann, S., Hopler, J., Kraft, M., Gade, N., Gmeiner, J., Roden, D., Saleh, I., Hagl, C., Nickenig, G., Massberg, S., Zimmer, S., Jamin, R. N. & Scherer, C. Crit Care Explor 6, e1117 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39045433
A genome-wide association meta-analysis of all-cause and vascular dementia. Mega Vascular Cognitive, I. & Dementia, c. Alzheimers Dement (2024). https://www.ncbi.nlm.nih.gov/pubmed/39046104
CardioTwins: case report of a transcatheter mitral and tricuspid valve implantation in one patient. Schmidt, T., Kuck, K. H., Marquetand, C., Eitel, I. & Frerker, C. Eur Heart J Case Rep 8, ytae336 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39045523
Innate immune memory after brain injury drives inflammatory cardiac dysfunction. Simats, A., Zhang, S., Messerer, D., Chong, F., Beskardes, S., Chivukula, A. S., Cao, J., Besson-Girard, S., Montellano, F. A., Morbach, C., Carofiglio, O., Ricci, A., Roth, S., Llovera, G., Singh, R., Chen, Y., Filser, S., Plesnila, N., Braun, C., Spitzer, H., Gokce, O., Dichgans, M., Heuschmann, P. U., Hatakeyama, K., Beltran, E., Clauss, S., Bonev, B., Schulz, C. & Liesz, A. Cell (2024). https://www.ncbi.nlm.nih.gov/pubmed/39043180
Outcome risk model development for heterogeneity of treatment effect analyses: a comparison of non-parametric machine learning methods and semi-parametric statistical methods. Xu, E., Vanghelof, J., Wang, Y., Patel, A., Furst, J., Raicu, D. S., Neumann, J. T., Wolfe, R., Gao, C. X., McNeil, J. J., Shah, R. C. & Tchoua, R. BMC Med Res Methodol 24, 158 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39044195
Transverse aortic constriction multi-omics analysis uncovers pathophysiological cardiac molecular mechanisms. Gjerga, E., Dewenter, M., Britto-Borges, T., Grosso, J., Stein, F., Eschenbach, J., Rettel, M., Backs, J. & Dieterich, C. Database (Oxford) 2024 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39051433
Iron scavenging and myeloid cell polarization. Ludwig, N., Cucinelli, S., Hametner, S., Muckenthaler, M. U. & Schirmer, L. Trends Immunol 45, 625-638 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39054114
Left ventricular diastolic function assessed by speckle tracking echocardiography in patients with left ventricular aneurysm. Nemchyna, O., Solowjowa, N., Hrytsyna, Y., Dandel, M., Merke, N., Knierim, J., Schoenrath, F., Just, I. A., Hennig, F., Hohendanner, F., Falk, V. & Knosalla, C. Int J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/39052191
Impact of peripheral thyroid hormone balance on liver fat: insights from the NutriAct trial. Sommer-Ballarini, M., Nguyen, T. H., Pletsch-Borba, L., Wernicke, C., Tacke, F., Schwerdtle, T., Pellowski, D., Machann, J., Spranger, J., Wirth, E. K. & Mai, K. Eur J Endocrinol 191, 183-191 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39049801
Combined Organ Transplantation in Patients with Advanced Liver Disease. Zhang, I. W., Lurje, I., Lurje, G., Knosalla, C., Schoenrath, F., Tacke, F. & Engelmann, C. Semin Liver Dis (2024). https://www.ncbi.nlm.nih.gov/pubmed/39053507
Lysozyme 1 Inflamed CCR2(+) Macrophages Promote Obesity-Induced Cardiac Dysfunction. Zhang, L., Han, H., Xu, A., Sathe, A., Fu, S., Zhao, J., Cai, W., Yang, Y., Liu, J., Bai, H., Ben, J., Zhu, X., Li, X., Yang, Q., Wang, Z., Gu, Y., Xing, C., Schiattarella, G. G., Cheng, S. Y., Zhang, H. & Chen, Q. Circ Res 135, 596-613 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39056179
CITED4 gene therapy protects against maladaptive cardiac remodeling after ischemia/reperfusion injury in mice. Lerchenmuller, C., Hastings, M. H., Rabolli, C. P., Betge, F., Roshan, M., Liu, L. X., Liu, X., Hess, C., Roh, J. D., Platt, C., Bezzerides, V., Busch, M., Katus, H. A., Frey, N., Most, P. & Rosenzweig, A. Mol Ther (2024). https://www.ncbi.nlm.nih.gov/pubmed/39066479
[Shortfalls of new data 2017-2020 in the German transplant registry]. Otto, G., Budde, K., Bara, C. & Gottlieb, J. Dtsch Med Wochenschr (2024). https://www.ncbi.nlm.nih.gov/pubmed/39059414
Quantifying and visualizing abdominal hemodynamics in patients with Fontan circulation by 4D phase-contrast flow magnetic resonance imaging at 1.5 T. Salehi Ravesh, M., Langguth, P., Moritz, J. D., Rinne, K., Harneit, P. L., Schulze-Nagel, J., Graessner, J., Uebing, A., Jansen, O., Both, M. & Hansen, J. H. Int J Cardiol 413, 132391 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39059472
Impulse initiation in engrafted pluripotent stem cell-derived cardiomyocytes can stimulate the recipient heart. Studemann, T., Schwarzova, B., Schneidewind, T., Geertz, B., von Bibra, C., Nehring, M., Rossinger, J., Wiegert, J. S., Eschenhagen, T. & Weinberger, F. Stem Cell Reports 19, 1053-1060 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39059379
Mechanical versus Biological Mitral Valve Replacement: Insights from Propensity Score Matching on Survival and Reoperation Rates. Feirer, N., Buchner, A., Weber, M., Lang, M., Dzilic, E., Amabile, A., Geirsson, A., Trenkwalder, T., Krane, M. & Vitanova, K. J Thorac Cardiovasc Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39067811
An executive summary on the Global conceptual definition of Sarcopenia. Kirk, B., Cawthon, P. M., Arai, H., Avila-Funes, J. A., Barazzoni, R., Bhasin, S., Binder, E. F., Bruyere, O., Cederholm, T., Chen, L. K., Cooper, C., Duque, G., Fielding, R. A., Guralnik, J., Kiel, D. P., Landi, F., Reginster, J. Y., Sayer, A. A., Visser, M., von Haehling, S., Woo, J., Cruz-Jentoft, A. J. & Global Leadership Initiative in Sarcopenia, G. Aging Clin Exp Res 36, 153 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39066819
"Re-evaluation of variants of uncertain significance in patients with hereditary arrhythmogenic disorders". Martin, S., Jenewein, T., Geisen, C., Scheiper-Welling, S. & Kauferstein, S. BMC Cardiovasc Disord 24, 390 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39068400
Genomic privacy preservation in genome-wide association studies: taxonomy, limitations, challenges, and vision. Aherrahrou, N., Tairi, H. & Aherrahrou, Z. Brief Bioinform 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39073827
GWAS breakthroughs: mapping the journey from one locus to 393 significant CAD associations. Aherrahrou, R., Reinberger, T., Hashmi, S. & Erdmann, J. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39073758
Publisher Correction: Quantitative flow ratio or angiography for the assessment of non-culprit lesions in acute coronary syndromes, a randomized trial. Ullrich-Daub, H., Olschewski, M., Schnorbus, B., Belhadj, K. A., Kohler, T., Vosseler, M., Munzel, T. & Gori, T. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39073452
Outcomes after transcatheter mitral valve implantation in valve-in-valve, valve-in-ring, and valve-in-mitral annular calcification. Alvarez-Covarrubias, H. A., Joner, M., Lutz, M., Xhepa, E., Mayr, N. P., Lachmann, M., Cassese, S., Rheude, T., Pellegrini, C., Kufner, S., Schunkert, H., Kastrati, A., Erlebach, M., Lange, R. & Ruge, H. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39077791
Impact of a dedicated cardiac protocol on diagnosis of infective endocarditis in patients undergoing [(18)F]-FDG-thoracic digital-PET/CT - Effects of expertise level. Notohamiprodjo, S., Scheidhauer, K., Eiber, M., Yakushev, I., Villagran Asiares, A., Kraus-Deuringer, J., Krebs-Fleischmann, H. W. A., Kleiner, S., Eggerstedt, R., Eglseder, B., Weber, W. A. & Nekolla, S. G. J Nucl Cardiol, 102010 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39074602
Self-supervised learning for improved calibrationless radial MRI with NLINV-Net. Blumenthal, M., Fantinato, C., Unterberg-Buchwald, C., Haltmeier, M., Wang, X. & Uecker, M. Magn Reson Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39080844
Interventional closure of an iatrogenic LAA-perforation by means of a PFO-occluder. Genske, F., Marquetand, C., Schmidt, T., Stiermaier, T. & Eitel, I. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39082843
GPT-4 Analysis of MRI Reports in Suspected Myocarditis: A Multicenter Study. Kaya, K., Gietzen, C., Hahnfeldt, R., Zoubi, M., Emrich, T., Halfmann, M. C., Sieren, M. M., Elser, Y., Krumm, P., Brendel, J. M., Nikolaou, K., Haag, N., Borggrefe, J., Kruchten, R. V., Muller-Peltzer, K., Ehrengut, C., Denecke, T., Hagendorff, A., Goertz, L., Gertz, R. J., Bunck, A. C., Maintz, D., Persigehl, T., Lennartz, S., Luetkens, J. A., Jaiswal, A., Iuga, A. I., Pennig, L. & Kottlors, J. J Cardiovasc Magn Reson, 101068 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39079602
A powerful safety net: Social support moderates the association of quality of life deficits with suicidal ideation in long-term childhood cancer survivors. Schwinn, T., Hirschmiller, J., Brahler, E., Merzenich, H., Faber, J., Wild, P. S., Beutel, M. E. & Ernst, M. J Psychosoc Oncol, 1-18 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39083714
Effects of high- versus low-intensity lipid-lowering treatment in patients undergoing serial coronary computed tomography angiography: results of the multi-center LOCATE study. Weichsel, L., Andre, F., Renker, M., Breitbart, P., Overhoff, D., Beer, M., Giesen, A., Vattay, B., Buss, S., Marwan, M., Schlett, C. L., Giannopoulos, A. A., Kelle, S., Frey, N., Korosoglou, G. & Investigators, L. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39080016
June
Paper of the Month
Prediction of diagnosis and diastolic filling pressure by AI-enhanced cardiac MRI: a modelling study of hospital data
DZHK authors: David Hermann Lehmann, Bruna Gomes, Ali Amr, Christoph Reich, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Jan Haas, Florian André, Sandy Engelhardt, Hugo A Katus, Norbert Frey, Benjamin Meder. The Lancet Digital Health.
Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied radiomics. Floca, R., Bohn, J., Haux, C., Wiestler, B., Zollner, F. G., Reinke, A., Weiss, J., Nolden, M., Albert, S., Persigehl, T., Norajitra, T., Baessler, B., Dewey, M., Braren, R., Buchert, M., Fallenberg, E. M., Galldiks, N., Gerken, A., Gotz, M., Hahn, H. K., Haubold, J., Haueise, T., Grosse Hokamp, N., Ingrisch, M., Iuga, A. I., Janoschke, M., Jung, M., Kiefer, L. S., Lohmann, P., Machann, J., Moltz, J. H., Nattenmuller, J., Nonnenmacher, T., Oerther, B., Othman, A. E., Peisen, F., Schick, F., Umutlu, L., Wichtmann, B. D., Zhao, W., Caspers, S., Schlemmer, H. P., Schlett, C. L., Maier-Hein, K. & Bamberg, F. Insights Imaging 15, 124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38825600
Type 1 Myocardial Infarction in Patients With Acute Ischemic Stroke. Nolte, C. H., von Rennenberg, R., Litmeier, S., Leistner, D. M., Szabo, K., Baumann, S., Mengel, A., Michalski, D., Siepmann, T., Blankenberg, S., Petzold, G. C., Dichgans, M., Katus, H., Pieske, B., Regitz-Zagrosek, V., Braemswig, T. B., Rangus, I., Pepic, A., Vettorazzi, E., Zeiher, A. M., Scheitz, J. F., Wegscheider, K., Landmesser, U. & Endres, M. JAMA Neurol 81, 703-711 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38829625
Biological basis and treatment of frailty and sarcopenia. Sato, R., Vatic, M., Peixoto da Fonseca, G. W., Anker, S. D. & von Haehling, S. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38828887
The significant impact of experimental variables on the gut microbiome. Zakarauskas-Seth, B. I. & Sawamiphak, S. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38830015
[Acute ischemic stroke and troponin elevation: update of the Mannheim clinical algorithm]. Becker, L., Alonso, A., Kruska, M., Baumann, S., Grassl, N., Lesch, H., Eisele, P., Sieburg, T., Behnes, M., Schupp, T., Kayed, H., Platten, M., Duerschmied, D., Szabo, K., Akin, I. & Fastner, C. Inn Med (Heidelb) 65, 830-839 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38831047
Standardisation in Paediatric Echocardiography Reporting and Critical Interpretation of Measurements, Functional Parameters and Prediction Scores. A Clinical Consensus Statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC and the Association for European Paediatric and Congenital Cardiology (AEPC). Cantinotti, M., Di Salvo, G., Voges, I., Raimondi, F., Greil, G., Ortiz Garrido, A., Bharucha, T., Grotenhuis, H. B., Kostenberger, M., Bonnello, B., Miller, O. & McMahon, C. J. Eur Heart J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38833586
Transient stabilization of human cardiovascular progenitor cells from hPSCs in vitro reflects stage-specific heart development in vivo. Emiliano, B., Dorothee, B., Iyer, L. M., Dorota, Z., Nina, F., Michael, M., Lucas, L., David, G., Nadine, S., Andreas, L., Wunder, J., Annika, F., Lika, D., Sebra, R., Axel, S., Alexander, G., Nicole, D., Gergana, D., Alessandra, M., Zelarayan, L. C., Salim, A. S. & Robert, Z. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38836637
A Man in His 50s With Dyspnea and Eosinophilia. Jakobs, K. C., Rauch, U. & Heidecker, B. JAMA Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38837171
Mapping the interplay of atrial fibrillation, brain structure, and cognitive dysfunction. Petersen, M., Chevalier, C., Naegele, F. L., Ingwersen, T., Omidvarnia, A., Hoffstaedter, F., Patil, K., Eickhoff, S. B., Schnabel, R. B., Kirchhof, P., Schlemm, E., Cheng, B., Thomalla, G. & Jensen, M. Alzheimers Dement 20, 4512-4526 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38837525
Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner. Wang, Y., Li, G., Chen, B., Shakir, G., Volz, M., van der Vorst, E. P. C., Maas, S. L., Geiger, M., Jethwa, C., Bartelt, A., Li, Z., Wettich, J., Sachs, N., Maegdefessel, L., Nazari Jahantigh, M., Hristov, M., Lacy, M., Lutz, B., Weber, C., Herzig, S., Guillamat Prats, R. & Steffens, S. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38838211
Unloading in cardiogenic shock: the rationale and current evidence. Besch, L. & Schrage, B. Curr Opin Crit Care 30, 379-384 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38841993
Association between socioeconomic and psychosocial factors with use of interventional and surgical treatments and outcomes in patients with myocardial infarction - Inpatient data of the largest European health care system. Hahad, O., Hobohm, L., Al-Kindi, S., Schmitt, V. H., Kazemi-Asrar, F., Gilan, D., Petrowski, K., Gori, T., Wild, P., Lieb, K., Daiber, A., Lurz, P., Munzel, T. & Keller, K. Eur J Intern Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839532
Left Atrial Reservoir Strain and Recurrence of Atrial Fibrillation Following De-Novo Pulmonary Vein Isolation - Results of the ASTRA-AF Pilot Study. Knappe, D., Vogler, J., Weimann, J., Banas, V., Obergassel, J., Yildirim, S., Memenga, F., Senftinger, J., Keil, L., Ismaili, D., Nies, M., Rillig, A., Willems, S., Blankenberg, S., Kirchhof, P., Metzner, A. & Sinning, C. Circ J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839350
Routine postdilation after 23 mm Sapien 3 Ultra implantation in the aortic position. Leone, P. P., Sturla, M., Spring, A. M., Echarte-Morales, J., Scotti, A., Ludwig, S., Coisne, A., Slipczuk, L., Assafin, M., Chau, M., Ho, E. C., Granada, J. F. & Latib, A. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/38841916
Inhibition of autophagy prevents cardiac dysfunction at early stages of cardiomyopathy in Bag3-deficient hearts. Maroli, G., Schanzer, A., Gunther, S., Garcia-Gonzalez, C., Rupp, S., Schlierbach, H., Chen, Y., Graumann, J., Wietelmann, A., Kim, J. & Braun, T. J Mol Cell Cardiol 193, 53-66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38838815
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction. Schormair, B., Zhao, C., Bell, S., Didriksen, M., Nawaz, M. S., Schandra, N., Stefani, A., Hogl, B., Dauvilliers, Y., Bachmann, C. G., Kemlink, D., Sonka, K., Paulus, W., Trenkwalder, C., Oertel, W. H., Hornyak, M., Teder-Laving, M., Metspalu, A., Hadjigeorgiou, G. M., Polo, O., Fietze, I., Ross, O. A., Wszolek, Z. K., Ibrahim, A., Bergmann, M., Kittke, V., Harrer, P., Dowsett, J., Chenini, S., Ostrowski, S. R., Sorensen, E., Erikstrup, C., Pedersen, O. B., Topholm Bruun, M., Nielsen, K. R., Butterworth, A. S., Soranzo, N., Ouwehand, W. H., Roberts, D. J., Danesh, J., Burchell, B., Furlotte, N. A., Nandakumar, P., andMe Research, T., group, D. E. S. I. R. s., Earley, C. J., Ondo, W. G., Xiong, L., Desautels, A., Perola, M., Vodicka, P., Dina, C., Stoll, M., Franke, A., Lieb, W., Stewart, A. F. R., Shah, S. H., Gieger, C., Peters, A., Rye, D. B., Rouleau, G. A., Berger, K., Stefansson, H., Ullum, H., Stefansson, K., Hinds, D. A., Di Angelantonio, E., Oexle, K. & Winkelmann, J. Nat Genet 56, 1090-1099 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839884
Gender-specific aspects of socialisation and risk of cardiovascular disease among community-dwelling older adults: a prospective cohort study using machine learning algorithms and a conventional method. Teshale, A. B., Htun, H. L., Owen, A. J., Ryan, J., Baker, J. R., Vered, M., Reid, C. M., Woods, R. L., Berk, M., Tonkin, A., Neumann, J. T., Kilkenny, M. F., Phyo, A. Z. Z., Nelson, M. R., Stocks, N., Britt, C. & Freak-Poli, R. J Epidemiol Community Health (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839108
Atrial fibrillation after patent foramen ovale closure in patients with embolic stroke of undetermined source. von Falkenhausen, A. S., Keidel, L. M., Wischmann, J., Hoglinger, G., Massberg, S., Kaab, S., Kellert, L. & Sinner, M. F. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38842105
Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure: Baseline characteristics of patients in the RESHAPE-HF2 trial and comparison to COAPT and MITRA-FR trials. Anker, S. D., Friede, T., von Bardeleben, R. S., Butler, J., Khan, M. S., Diek, M., Heinrich, J., Geyer, M., Placzek, M., Ferrari, R., Abraham, W. T., Alfieri, O., Auricchio, A., Bayes-Genis, A., Cleland, J. G. F., Filippatos, G., Gustafsson, F., Haverkamp, W., Kelm, M., Kuck, K. H., Landmesser, U., Maggioni, A. P., Metra, M., Ninios, V., Petrie, M. C., Rassaf, T., Ruschitzka, F., Schafer, U., Schulze, P. C., Spargias, K., Vahanian, A., Zamorano, J. L., Zeiher, A., Karakas, M., Koehler, F., Lainscak, M., Oner, A., Mezilis, N., Theofilogiannakos, E. K., Ninios, I., Chrissoheris, M., Kourkoveli, P., Papadopoulos, K., Smolka, G., Wojakowski, W., Reczuch, K., Pinto, F. J., Zmudka, K., Kalarus, Z., Adamo, M., Santiago-Vacas, E., Ruf, T. F., Gross, M., Tongers, J., Hasenfuss, G., Schillinger, W. & Ponikowski, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38847420
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia. Dill, V., Kirmes, K., Han, J., Klug, M., Rosenbaum, M., Viggiani, G., von Scheidt, M., List, M., Herhaus, P., Ruland, J., Bassermann, F., Laugwitz, K. L., Gotze, K. S., Jost, P. J., Jilg, S., Bloxham, C. J., Raake, P. W. J., Bernlochner, I. & Bongiovanni, D. Platelets 35, 2358244 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38845541
Oral anticoagulation in patients with left ventricular thrombus - a systematic review and meta-analysis. Haller, P. M., Kazem, N., Agewall, S., Borghi, C., Ceconi, C., Dobrev, D., Cerbai, E., Grove, E. L., Kaski, J. C., Lewis, B. S., Niessner, A., Rocca, B., Rosano, G., Savarese, G., Schnabel, R., Semb, A. G., Sossalla, S., Wassmann, S. & Sulzgruber, P. Eur Heart J Cardiovasc Pharmacother (2024). https://www.ncbi.nlm.nih.gov/pubmed/38845369
Simulation of thoracic endovascular aortic repair in a perfused patient-specific model of type B aortic dissection. Mohl, L., Karl, R., Hagedorn, M. N., Runz, A., Skornitzke, S., Toelle, M., Bergt, C. S., Hatzl, J., Uhl, C., Bockler, D., Meisenbacher, K. & Engelhardt, S. Int J Comput Assist Radiol Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38848033
Fronto-thalamic networks and the left ventral thalamic nuclei play a key role in aphasia after thalamic stroke. Rangus, I., Rios, A. S., Horn, A., Fritsch, M., Khalil, A., Villringer, K., Udke, B., Ihrke, M., Grittner, U., Galinovic, I., Al-Fatly, B., Endres, M., Kufner, A. & Nolte, C. H. Commun Biol 7, 700 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38849518
Impact of Patient-Prosthesis Mismatch on Long-term Outcomes After Aortic Valve Replacement. Graser, M., Bleiziffer, S., Zittermann, A., Mayr, B., Sideris, K., Puluca, N., Krane, M. & Prinzing, A. Ann Thorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38851414
Right heart failure with left ventricular assist devices: Preoperative, perioperative and postoperative management strategies. A clinical consensus statement of the Heart Failure Association (HFA) of the ESC. Adamopoulos, S., Bonios, M., Ben Gal, T., Gustafsson, F., Abdelhamid, M., Adamo, M., Bayes-Genis, A., Bohm, M., Chioncel, O., Cohen-Solal, A., Damman, K., Di Nora, C., Hashmani, S., Hill, L., Jaarsma, T., Jankowska, E., Lopatin, Y., Masetti, M., Mehra, M. R., Milicic, D., Moura, B., Mullens, W., Nalbantgil, S., Panagiotou, C., Piepoli, M., Rakisheva, A., Ristic, A., Rivinius, R., Savarese, G., Thum, T., Tocchetti, C. G., Tops, L. F., Van Laake, L. W., Volterrani, M., Seferovic, P., Coats, A., Metra, M. & Rosano, G. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38853659
Transcatheter aortic valve replacement in patients with severe aortic valve stenosis and concomitant mitral valve regurgitation - 5 years follow-up. Henrique Rangel, R., Christoph Voran, J., Seoudy, H., Villinger, T., Lutter, G., Puehler, T., Kreidel, F., Frank, J., Salem, M., Frank, D. & Saad, M. Int J Cardiol Heart Vasc 53, 101416 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38854408
Pilot study to evaluate the use of remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): study protocol for a randomised controlled trial delivered in two tertiary cardiac centres in the UK. Khan, N., Steeds, R. P., Kyte, D., Fabritz, L., Collis, P., Chua, W., Stubbs, C., Mehta, S., Sun, Y., Nulty, M., Kirkham, K. & Cotton, J. M. BMJ Open 14, e086587 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38858149
Incidence, Implications, and Management of Sense-B-Noise Failure in Subcutaneous Cardioverter-Defibrillator Patients: insights from a large Multicenter Registry. Wormann, J., Strik, M., Jurisic, S., Stout, K., Elrefai, M., Becher, N., Schaer, B., van Stipdonk, A., Srinivasan, N. T., Ploux, S., Breitenstein, A., Kron, J., Roberts, P. R., Toennis, T., Linz, D., Dulai, R., Hermes-Laufer, J., Koneru, J., Erkuner, O., Dittrich, S., van den Bruck, J. H., Schipper, J. H., Sultan, A., Rosenberger, K. D., Steven, D. & Luker, J. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38861398
Non-invasive assessment of left ventricular contractility by myocardial work index in veno-arterial membrane oxygenation patients: rationale and design of the MIX-ECMO multicentre observational study. Lakatos, B. K., Ladanyi, Z., Fabian, A., Ehrenberger, R., Turschl, T., Bagyura, Z., Evrard, B., Vandroux, D., Goudelin, M., Lindner, S., Britsch, S., Durschmied, D., Zima, E., Csikos, G. R., Turoczi, Z., Soltesz, A., Nemeth, E., Kovacs, A., Edes, F. I. & Merkely, B. Front Cardiovasc Med 11, 1399874 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38863897
Central obesity and fat-free mass are associated with a larger spleen volume in the general population. Mousa, M. F. M., Naeem, M., Bibi, S., Bulow, R., Bahls, M., Siewert-Markus, U., Topfer, P., Aghdassi, A., Khattak, M. N. K., Volzke, H., Markus, M. R. & Ittermann, T. Ups J Med Sci 129 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38863728
Reduced olfactory bulb volume accompanies olfactory dysfunction after mild SARS-CoV-2 infection. Petersen, M., Becker, B., Schell, M., Mayer, C., Naegele, F. L., Petersen, E., Twerenbold, R., Thomalla, G., Cheng, B., Betz, C. & Hoffmann, A. S. Sci Rep 14, 13396 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38862636
Targeting obesity for therapeutic intervention in heart failure patients. Sato, R. & von Haehling, S. Expert Rev Cardiovasc Ther 22, 217-230 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38864827
Diagnostic value of left ventricular layer strain and specific regional strain patterns in cardiac amyloidosis and Fabry disease. Steudel, T., Barzen, G., Frumkin, D., Romero-Dorta, E., Spethmann, S., Hindricks, G., Stangl, K., Knebel, F., Heidecker, B., Canaan-Kuhl, S., Pernice, H. F., Hahn, K., Mattig, I. & Brand, A. Eur Heart J Open 4, oeae041 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38863522
Noncalcific Transcatheter Heart Valve Dysfunction: Novel Dogma or Simple Precursor? Joner, M. & Xhepa, E. JACC Cardiovasc Interv 17, 1352-1355 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38866458
Impact of telemedical management on hospitalization and mortality in heart failure patients with diabetes: a post-hoc subgroup analysis of the TIM-HF2 trial. Koehler, F., Koehler, J., Bramlage, P., Vettorazzi, E., Wegscheider, K., Lezius, S., Spethmann, S., Iakoubov, R., Vijayan, A., Winkler, S., Melzer, C., Schutt, K., Dessapt-Baradez, C., Paar, W. D., Koehler, K. & Muller-Wieland, D. Cardiovasc Diabetol 23, 198 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38867198
Hydrodynamic Assessment of Explanted Degenerated Transcatheter Aortic Valves: Novel Insights Into Noncalcific and Calcific Mechanisms. Sathananthan, J., Nigade, A., Meier, D., Navarro, D., Spencer, J., Lai, A., Gill, H., Pirelli, L., Webb, J. G., Wood, D. A., Lutter, G., Puehler, T., Tang, G. H. L., Fukuhara, S. & Sellers, S. L. JACC Cardiovasc Interv 17, 1340-1351 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38866457
Spoiled for Choice: P2Y(12) Receptor Inhibition in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention. Sibbing, D., Massberg, S. & Rizas, K. D. JACC Cardiovasc Interv 17, 1371-1373 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38866459
Associations between multiple neurological biomarkers and distal sensorimotor polyneuropathy: KORA F4/FF4 study. Herder, C., Thorand, B., Strom, A., Rathmann, W., Heier, M., Koenig, W., Morrison, H., Ziegler, D., Roden, M., Peters, A., Bonhof, G. J. & Maalmi, H. Diabetes Metab Res Rev 40, e3807 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38872492
Pathomechanistic Synergy Between Particulate Matter and Traffic Noise-Induced Cardiovascular Damage and the Classical Risk Factor Hypertension. Kuntic, M., Hahad, O., Al-Kindi, S., Oelze, M., Lelieveld, J., Daiber, A. & Munzel, T. Antioxid Redox Signal (2024). https://www.ncbi.nlm.nih.gov/pubmed/38874533
Lower muscular strength is associated with greater liver fat content and higher serum liver enzymes-"The Sedentary's Liver" The Study of Health in Pomerania. Mayer, C., Ittermann, T., Schipf, S., Gross, S., Kim, S., Schielke, J., Bulow, R., Kuhn, J. P., Lerch, M. M., Volzke, H., Felix, S. B., Bahls, M., Targher, G., Dorr, M. & Markus, M. R. P. Eur J Sport Sci 24, 824-833 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38874978
Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension. Zhang, Q., Yaoita, N., Tabuchi, A., Liu, S., Chen, S. H., Li, Q., Hegemann, N., Li, C., Rodor, J., Timm, S., Laban, H., Finkel, T., Stevens, T., Alvarez, D. F., Erfinanda, L., de Perrot, M., Kucherenko, M. M., Knosalla, C., Ochs, M., Dimmeler, S., Korff, T., Verma, S., Baker, A. H. & Kuebler, W. M. Circulation 150, 466-487 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38873770
CMR-based cardiac phenotyping in different forms of heart failure. Lange, T., Backhaus, S. J., Schulz, A., Hashemi, D., Evertz, R., Kowallick, J. T., Hasenfuss, G., Kelle, S. & Schuster, A. Int J Cardiovasc Imaging 40, 1585-1596 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38878148
STING orchestrates the neuronal inflammatory stress response in multiple sclerosis. Woo, M. S., Mayer, C., Binkle-Ladisch, L., Sonner, J. K., Rosenkranz, S. C., Shaposhnykov, A., Rothammer, N., Tsvilovskyy, V., Lorenz, S. M., Raich, L., Bal, L. C., Vieira, V., Wagner, I., Bauer, S., Glatzel, M., Conrad, M., Merkler, D., Freichel, M. & Friese, M. A. Cell (2024). https://www.ncbi.nlm.nih.gov/pubmed/38878778
Editorial: Proteostasis in cardiac health and disease. Buhringer, H., Doroudgar, S., Wang, X., Frey, N. & Rangrez, A. Y. Front Mol Biosci 11, 1433721 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38882607
Personalized nutritional prevention for Lp(a): PUFAs seem to do the job. Lehnert, K., Konemann, S. & Bahls, M. Atherosclerosis 395, 117597 (2024). www.ncbi.nlm.nih.gov/pubmed/38880705
Occurrence of Premature Battery Depletion in a Large Multicenter Registry of Subcutaneous Cardioverter-Defibrillator Patients. Wormann, J., Strik, M., Jurisic, S., Stout, K., Elrefai, M., Becher, N., Schaer, B., van Stipdonk, A., Srinivasan, N. T., Ploux, S., Breitenstein, A., Kron, J., Roberts, P. R., Toennis, T., Linz, D., Dulai, R., Hermes-Laufer, J., Koneru, J., Erkuner, O., Dittrich, S., van den Bruck, J. H., Schipper, J. H., Sultan, A., Rosenberger, K. D., Steven, D. & Luker, J. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38885309
Cardiac fibrosis as a predictor for sudden cardiac death after transcatheter aortic valve implantation. Alnour, F., Beuthner, B. E., Hakroush, S., Topci, R., Vogelgesang, A., Lange, T., Seidler, T., Kutschka, I., Toischer, K., Schuster, A., Jacobshagen, C., Leha, A., Zabel, M., Hasenfuss, G., Puls, M. & Zeisberg, E. M. EuroIntervention20, e760-e769 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38887885
Perfect Match: Radiomics and Artificial Intelligence in Cardiac Imaging. Baessler, B., Engelhardt, S., Hekalo, A., Hennemuth, A., Hullebrand, M., Laube, A., Scherer, C., Tolle, M. & Wech, T. Circ Cardiovasc Imaging 17, e015490 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38889216
Epstein-Barr Virus Lytic Transcripts Correlate with the Degree of Myocardial Inflammation in Heart Failure Patients. Baumeier, C., Harms, D., Altmann, B., Aleshcheva, G., Wiegleb, G., Bock, T., Escher, F. & Schultheiss, H. P. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38892033
Backwash Maneuver for HeartMate3 Inflow Thrombosis: Experience From Two Cases. Cholevas, N., Hoermandinger, C., Just, I. A., Politis, N., Falk, V., Potapov, E. & Schoenrath, F. ASAIO J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896847
Catecholamine induces endothelial dysfunction via Angiotensin II and intermediate conductance calcium activated potassium channel. Fan, X., Yang, G., Yang, Z., Uhlig, S., Sattler, K., Bieback, K., Hamdani, N., El-Battrawy, I., Duerschmied, D., Zhou, X. & Akin, I. Biomed Pharmacother 177, 116928 (2024). www.ncbi.nlm.nih.gov/pubmed/38889637
Na(V)1.8 as Proarrhythmic Target in a Ventricular Cardiac Stem Cell Model. Hartmann, N., Knierim, M., Maurer, W., Dybkova, N., Zeman, F., Hasenfuss, G., Sossalla, S. & Streckfuss-Bomeke, K. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38892333
Long-term risk factor management and adverse events in patients with early-onset myocardial infarction-a "real-world" study. Kerniss, H., Marin, L. A. M., Clemens, K., Litfin, C., Seidel-Sarpong, A., Hanses, U., Ruhle, S., Schmucker, J., Osteresch, R., Fach, A., Eitel, I., Hambrecht, R. & Wienbergen, H. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896124
Gait Variability as a Potential Motor Marker of Cerebellar Disease-Relationship between Variability of Stride, Arm Swing and Trunk Movements, and Walking Speed. Kroneberg, D., Numann, A., Minnerop, M., Ronnefarth, M., Endres, M., Kuhn, A. A., Paul, F., Doss, S., Solbrig, S., Elshehabi, M., Maetzler, W. & Schmitz-Hubsch, T. Sensors (Basel) 24 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38894268
Electrophysiological Effects of the Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitor Dapagliflozin on Human Cardiac Potassium Channels. Muller, M. E., Petersenn, F., Hackbarth, J., Pfeiffer, J., Gampp, H., Frey, N., Lugenbiel, P., Thomas, D. & Rahm, A. K. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38891889
3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models. Saleem, H. N., Ignatyeva, N., Stuut, C., Jakobs, S., Habeck, M. & Ebert, A. Cells 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38891055
Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. Seferovic, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschope, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalic, N., Ceriello, A., Dohner, W., Ristic, A., Milinkovic, I., Seferovic, J., Cosentino, F., Metra, M. & Coats, A. J. S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896048
Functional Mitral Valve Regurgitation: Mitral Valve Repair or Replacement? Our "Road Map" for the Appropriate Strategy. Sideris, K., Burri, M., Mayr, A., Voss, S., Vitanova, K., Prinzing, A., Voss, B., Amabile, A., Geirsson, A., Krane, M. & Guenzinger, R. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38892978
Prevention and rehabilitation after heart transplantation: A clinical consensus statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a section of ESOT. Simonenko, M., Hansen, D., Niebauer, J., Volterrani, M., Adamopoulos, S., Amarelli, C., Ambrosetti, M., Anker, S. D., Bayes-Genis, A., Gal, T. B., Bowen, T. S., Cacciatore, F., Caminiti, G., Cavaretta, E., Chioncel, O., Coats, A. J. S., Cohen-Solal, A., D'Ascenzi, F., de Pablo Zarzosa, C., Gevaert, A. B., Gustafsson, F., Kemps, H., Hill, L., Jaarsma, T., Jankowska, E., Joyce, E., Krankel, N., Lainscak, M., Lund, L. H., Moura, B., Nytroen, K., Osto, E., Piepoli, M., Potena, L., Rakisheva, A., Rosano, G., Savarese, G., Seferovic, P. M., Thompson, D. R., Thum, T. & Van Craenenbroeck, E. M. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38894688
Prevention and rehabilitation after heart transplantation: A clinical consensus statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a section of ESOT. Simonenko, M., Hansen, D., Niebauer, J., Volterrani, M., Adamopoulos, S., Amarelli, C., Ambrosetti, M., Anker, S. D., Bayes-Genis, A., Gal, T. B., Bowen, T. S., Cacciatore, F., Caminiti, G., Cavarretta, E., Chioncel, O., Coats, A. J. S., Cohen-Solal, A., D'Ascenzi, F., de Pablo Zarzosa, C., Gevaert, A. B., Gustafsson, F., Kemps, H., Hill, L., Jaarsma, T., Jankowska, E., Joyce, E., Krankel, N., Lainscak, M., Lund, L. H., Moura, B., Nytroen, K., Osto, E., Piepoli, M., Potena, L., Rakisheva, A., Rosano, G., Savarese, G., Seferovic, P. M., Thompson, D. R., Thum, T. & Van Craenenbroeck, E. M. Eur J Prev Cardiol31, 1385-1399 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38894688
Citrate-Buffered, Magnesium-Enriched Dialysate on Calcification Propensity in Hemodialysis Patients - The CitMag Study. Cejka, D., Thiem, U., Blinzler, E., Machacek, J., Voelkl, J., Smith, E. R., Pasch, A. & Haller, M. C. Kidney Int Rep 9, 1765-1773 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38899177
Cardiopulmonary Exercise Test and Daily Physical Activity in Pediatric Congenital Heart Disease: An Exploratory Analysis. Hock, J., Brudy, L., Willinger, L., Hager, A., Ewert, P., Oberhoffer-Fritz, R. & Muller, J. Am J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38897267
Physician-directed patient self-management in heart failure using left atrial pressure: Interim insights from the VECTOR-HF I and IIa studies. Meerkin, D., Perl, L., Hasin, T., Petriashvili, S., Kurashvili, L., Metreveli, M., Ince, H., Feickert, S., Habib, M., Caspi, O., Jonas, M., Amat-Santos, I. J., Bayes-Genis, A., Codina, P., Koren, O., Frydman, S., Pachino, R. M., Anker, S. D., Abraham, W. T., on behalf of the, V.-H. I. & Investigators, I. I. T. Eur J Heart Fail 26, 1814-1823 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38899626
The effect of a selenium-based anti-inflammatory strategy on postoperative functional recovery in high-risk cardiac surgery patients - A nested sub-study of the sustain CSX trial. Ott, S., Lee, Z. Y., Muller-Wirtz, L. M., Cangut, B., Roessler, J., Patterson, W., Thomas, C. M., Bekele, B. M., Windpassinger, M., Lobdell, K., Grant, M. C., Arora, R. C., Engelman, D. T., Fremes, S., Velten, M., O'Brien, B., Ruetzler, K., Heyland, D. K. & Stoppe, C. Life Sci 351, 122841 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38897349
Midterm results after aortic valve neocuspidization. Prinzing, A., Boehm, J., Burri, M., Schreyer, J., Lange, R. & Krane, M. JTCVS Tech 25, 35-42 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38899113
Childhood maltreatment and risk of metabolic dysfunction-associated steatotic liver disease - Evidence of sex-specific associations in the general population. Siewert-Markus, U., Ittermann, T., Klinger-Konig, J., Grabe, H. J., Stracke, S., Volzke, H., Targher, G., Dorr, M., Markus, M. R. P. & Topfer, P. J Psychosom Res183, 111829 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896985
Incidence and Prediction of Anoxic Brain Injury in Concomitant Cardiac Arrest and Cardiogenic Shock. Besch, L., Weimann, J., Jentzer, J., Beer, B., Dettling, A., Sundermeyer, J., Kirchhof, P., Blankenberg, S., Westermann, D. & Schrage, B. JACC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38904645
Correlation of diaphragm thickening fraction and oesophageal pressure swing in non-invasive ventilation of healthy subjects. Lindner, S., Hoermann, C., Teichert, J., Ziyadova, S., Michels-Zetsche, J. D., Neetz, B., Herth, F. J. F., Duerschmied, D. & Britsch, S. BMC Pulm Med 24, 289 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38902702
The role of concomitant coronary artery bypass grafting in acute type a aortic dissection complicated by coronary malperfusion. Pitts, L., Kofler, M., Montagner, M., Heck, R., Dominik Kurz, S., Sundermann, S., Falk, V. & Kempfert, J. Eur J Cardiothorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38905500
Intergenic risk variant rs56258221 skews the fate of naive CD4(+) T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis. Poch, T., Bahn, J., Casar, C., Krause, J., Evangelakos, I., Gilladi, H., Kunzmann, L. K., Laschtowitz, A., Iuso, N., Schafer, A. M., Liebig, L. A., Steinmann, S., Sebode, M., Folseraas, T., Engesaeter, L. K., Karlsen, T. H., Franke, A., Hubner, N., Schlein, C., Galun, E., Huber, S., Lohse, A. W., Gagliani, N., Schwinge, D. & Schramm, C. Cell Rep Med 5, 101620 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38901430
Small conductance calcium-activated potassium channel contributes to stress induced endothelial dysfunctions. Yang, Z., Li, Y., Huang, M., Li, X., Fan, X., Yan, C., Meng, Z., Liao, B., Hamdani, N., El-Battrawy, I., Yang, X., Zhou, X. & Akin, I. Microvasc Res 155, 104699 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38901735
Ferroptosis in health and disease. Berndt, C., Alborzinia, H., Amen, V. S., Ayton, S., Barayeu, U., Bartelt, A., Bayir, H., Bebber, C. M., Birsoy, K., Bottcher, J. P., Brabletz, S., Brabletz, T., Brown, A. R., Brune, B., Bulli, G., Bruneau, A., Chen, Q., DeNicola, G. M., Dick, T. P., Distefano, A., Dixon, S. J., Engler, J. B., Esser-von Bieren, J., Fedorova, M., Friedmann Angeli, J. P., Friese, M. A., Fuhrmann, D. C., Garcia-Saez, A. J., Garbowicz, K., Gotz, M., Gu, W., Hammerich, L., Hassannia, B., Jiang, X., Jeridi, A., Kang, Y. P., Kagan, V. E., Konrad, D. B., Kotschi, S., Lei, P., Le Tertre, M., Lev, S., Liang, D., Linkermann, A., Lohr, C., Lorenz, S., Luedde, T., Methner, A., Michalke, B., Milton, A. V., Min, J., Mishima, E., Muller, S., Motohashi, H., Muckenthaler, M. U., Murakami, S., Olzmann, J. A., Pagnussat, G., Pan, Z., Papagiannakopoulos, T., Pedrera Puentes, L., Pratt, D. A., Proneth, B., Ramsauer, L., Rodriguez, R., Saito, Y., Schmidt, F., Schmitt, C., Schulze, A., Schwab, A., Schwantes, A., Soula, M., Spitzlberger, B., Stockwell, B. R., Thewes, L., Thorn-Seshold, O., Toyokuni, S., Tonnus, W., Trumpp, A., Vandenabeele, P., Vanden Berghe, T., Venkataramani, V., Vogel, F. C. E., von Karstedt, S., Wang, F., Westermann, F., Wientjens, C., Wilhelm, C., Wolk, M., Wu, K., Yang, X., Yu, F., Zou, Y. & Conrad, M. Redox Biol 75, 103211 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38908072
Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation. Fakuade, F. E., Hubricht, D., Moller, V., Sobitov, I., Liutkute, A., Doring, Y., Seibertz, F., Gerloff, M., Pronto, J. R. D., Haghighi, F., Brandenburg, S., Alhussini, K., Ignatyeva, N., Bonhoff, Y., Kestel, S., El-Essawi, A., Jebran, A. F., Grossmann, M., Danner, B. C., Baraki, H., Schmidt, C., Sossalla, S., Kutschka, I., Bening, C., Maack, C., Linke, W. A., Heijman, J., Lehnart, S. E., Kensah, G., Ebert, A., Mason, F. E. & Voigt, N. Circulation 150, 544-559 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38910563
Functional characterization of PI3K C2 domain mutations detected in breast cancer circulating tumor cells and metastatic cells. Smit, D. J., Brauer, H., Horn, S., Yigit, G., Haider, M. T., Pogenberg, V., Schumacher, U., Pantel, K. & Jucker, M. Cell Signal, 111270 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38909932
Aging is associated with an insufficient early inflammatory response of lung endothelial cells in SARS-CoV-2 infection. Subramaniam, S., Kenney, D., Jayaraman, A., O'Connell, A. K., Walachowski, S., Montanaro, P., Reinhardt, C., Colucci, G., Crossland, N. A., Douam, F. & Bosmann, M. Front Immunol 15, 1397990 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38911865
Influence of donor age and donor-recipient age difference on intimal hyperplasia in pediatric patients with young and adult donors vs. adult patients after heart transplantation. Ulrich, S., Arnold, L., Michel, S., Tengler, A., Rosenthal, L., Hausleiter, J., Mueller, C. S., Schnabel, B., Stark, K., Rizas, K., Grabmaier, U., Mehilli, J., Jakob, A., Fischer, M., Birnbaum, J., Hagl, C., Massberg, S., Haas, N., Pozza, R. D. & Orban, M. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38913171
MRI-based adrenal gland volume is associated with cardiovascular alterations in individuals without prior cardiovascular disease. Askani, E., Rospleszcz, S., Lorbeer, R., Wintergerst, C., Muller-Peltzer, K., Nattenmuller, J., Hasic, D., von Kruchten, R., Kellner, E., Reisert, M., Rathmann, W., Peters, A., Schlett, C. L., Bamberg, F. & Storz, C. Sci Rep 14, 14664 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38918570
Cardiac aging: from hallmarks to therapeutic opportunities. Hastings, M. H., Zhou, Q., Wu, C., Shabani, P., Huang, S., Yu, X., Singh, A. P., Guseh, J. S., Li, H., Lerchenmuller, C. & Rosenzweig, A. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38918884
Towards Personalized TSH Reference Ranges: A Genetic and Population-Based Approach in Three Independent Cohorts. Kus, A., Sterenborg, R., Haug, E. B., Galesloot, T. E., Visser, W. E., Smit, J. W. A., Bednarczuk, T., Peeters, R. P., Asvold, B. O., Teumer, A. & Medici, M. Thyroid (2024). https://www.ncbi.nlm.nih.gov/pubmed/38919119
Open-ST: High-resolution spatial transcriptomics in 3D. Schott, M., Leon-Perinan, D., Splendiani, E., Strenger, L., Licha, J. R., Pentimalli, T. M., Schallenberg, S., Alles, J., Samut Tagliaferro, S., Boltengagen, A., Ehrig, S., Abbiati, S., Dommerich, S., Pagani, M., Ferretti, E., Macino, G., Karaiskos, N. & Rajewsky, N. Cell (2024). https://www.ncbi.nlm.nih.gov/pubmed/38917789
Management of cardiac sarcoidosis. Sharma, R., Kouranos, V., Cooper, L. T., Metra, M., Ristic, A., Heidecker, B., Baksi, J., Wicks, E., Merino, J. L., Klingel, K., Imazio, M., de Chillou, C., Tschope, C., Kuchynka, P., Petersen, S. E., McDonagh, T., Luscher, T. & Filippatos, G. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38923509
Sex differences in lipidomic and bile acid plasma profiles in patients with and without coronary artery disease. Bay, B., Fuh, M. M., Rohde, J., Worthmann, A., Gossling, A., Arnold, N., Koester, L., Lorenz, T., Blaum, C., Kirchhof, P., Blankenberg, S., Seiffert, M., Brunner, F. J., Waldeyer, C. & Heeren, J. Lipids Health Dis 23, 197 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38926753
Author Correction: Mechanisms controlling cellular and systemic iron homeostasis. Galy, B., Conrad, M. & Muckenthaler, M. Nat Rev Mol Cell Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38926532
Loss of Smooth Muscle Tenascin-X Inhibits Vascular Remodeling Through Increased TGF-beta Signaling. Liang, G., Lv, X. F., Huang, W., Jin, Y. J., Roquid, K. A., Kawase, H. & Offermanns, S. Arterioscler Thromb Vasc Biol 44, 1748-1763 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38934115
Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction: A Randomized Controlled Phase 3 Study. Hoeper, M. M., Oerke, B., Wissmuller, M., Leuchte, H., Opitz, C., Halank, M., Seyfarth, H. J., Baldus, S., Bauersachs, J., Bohm, M., Ghofrani, H. A., Konstantinides, S., Olsson, K. M., Wachter, R., Lam, C. S. P., Aminossadati, B. & Rosenkranz, S. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38939948
Causes of death in patients with atrial fibrillation anticoagulated with rivaroxaban: a pooled analysis of XANTUS. Kirchhof, P., Haas, S., Amarenco, P., Turpie, A. G. G., Bach, M., Lambelet, M., Hess, S. & Camm, A. J. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38941511
Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: Rationale & design of the ARCHER trial. McNamara, D. M., Cooper, L. T., Arbel, Y., Bhimaraj, A., Bocchi, E., Friedrich, M. G., Kerneis, M., Liu, P., Parker, A. B., Smith, E. R., Tang, W. H. W., Torre-Amione, G., Tschope, C. & Group, A. S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38937900
Somatic symptom disorder symptoms in individuals at risk for heart failure: A cluster analysis with cross-sectional data from a population-based cohort study. Clifford, C., Twerenbold, R., Hartel, F., Lowe, B. & Kohlmann, S. J Psychosom Res 184, 111848 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38941711
Amyloid beta is associated with carotid wall echolucency and atherosclerotic plaque composition. Delialis, D., Georgiopoulos, G., Tual-Chalot, S., Angelidakis, L., Aivalioti, E., Mavraganis, G., Sopova, K., Argyris, A., Kostakou, P., Konstantaki, C., Papaioannou, M., Tsilimigras, D., Chatoupis, K., Zacharoulis, A. A., Galyfos, G., Sigala, F., Stellos, K. & Stamatelopoulos, K. Sci Rep 14, 14944 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38942831
Single-nucleus transcriptomics reveals adrenergic and STAT3 signaling in paradoxical low-flow low-gradient -specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment. Xu, X., Tan, X., Cui, B., Paul, N. B., Elkenani, M., Beuthner, B. E., Li, W., Mohamed, B. A., Schnelle, M., Puls, M., Zeisberg, E. M., Zeisberg, M., Beissbarth, T., Toischer, K. & Hasenfuss, G. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38943668
Plasma infrared fingerprinting with machine learning enables single-measurement multi-phenotype health screening. Eissa, T., Leonardo, C., Kepesidis, K. V., Fleischmann, F., Linkohr, B., Meyer, D., Zoka, V., Huber, M., Voronina, L., Richter, L., Peters, A. & Zigman, M. Cell Rep Med 5, 101625 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38944038
May
Paper of the Month
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes
DZHK authors: Kami Pekayvaz, Christoph Gold, Rainer Kaiser, Sezer Akgöl, Tobias Petzold, Kathrin Saar, Philipp Mertins, Norbert Huebner, Steffen Massberg, Matthias Heinig, Leo Nicolai, Konstantin Stark. Nature Medicine.
All Three Supersystems-Nervous, Vascular, and Immune-Contribute to the Cortical Infarcts After Subarachnoid Hemorrhage. Dreier, J. P., Joerk, A., Uchikawa, H., Horst, V., Lemale, C. L., Radbruch, H., McBride, D. W., Vajkoczy, P., Schneider, U. C. & Xu, R. Transl Stroke Res (2024). https://pubmed.ncbi.nlm.nih.gov/38689162/
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Keaton, J. M., Kamali, Z., Xie, T., Vaez, A., Williams, A., Goleva, S. B., Ani, A., Evangelou, E., Hellwege, J. N., Yengo, L., Young, W. J., Traylor, M., Giri, A., Zheng, Z., Zeng, J., Chasman, D. I., Morris, A. P., Caulfield, M. J., Hwang, S. J., Kooner, J. S., Conen, D., Attia, J. R., Morrison, A. C., Loos, R. J. F., Kristiansson, K., Schmidt, R., Hicks, A. A., Pramstaller, P. P., Nelson, C. P., Samani, N. J., Risch, L., Gyllensten, U., Melander, O., Riese, H., Wilson, J. F., Campbell, H., Rich, S. S., Psaty, B. M., Lu, Y., Rotter, J. I., Guo, X., Rice, K. M., Vollenweider, P., Sundström, J., Langenberg, C., Tobin, M. D., Giedraitis, V., Luan, J., Tuomilehto, J., Kutalik, Z., Ripatti, S., Salomaa, V., Girotto, G., Trompet, S., Jukema, J. W., van der Harst, P., Ridker, P. M., Giulianini, F., Vitart, V., Goel, A., Watkins, H., Harris, S. E., Deary, I. J., van der Most, P. J., Oldehinkel, A. J., Keavney, B. D., Hayward, C., Campbell, A., Boehnke, M., Scott, L. J., Boutin, T., Mamasoula, C., Järvelin, M. R., Peters, A., Gieger, C., Lakatta, E. G., Cucca, F., Hui, J., Knekt, P., Enroth, S., De Borst, M. H., Polašek, O., Concas, M. P., Catamo, E., Cocca, M., Li-Gao, R., Hofer, E., Schmidt, H., Spedicati, B., Waldenberger, M., Strachan, D. P., Laan, M., Teumer, A., Dörr, M., Gudnason, V., Cook, J. P., Ruggiero, D., Kolcic, I., Boerwinkle, E., Traglia, M., Lehtimäki, T., Raitakari, O. T., Johnson, A. D., Newton-Cheh, C., Brown, M. J., Dominiczak, A. F., Sever, P. J., Poulter, N., Chambers, J. C., Elosua, R., Siscovick, D., Esko, T., Metspalu, A., Strawbridge, R. J., Laakso, M., Hamsten, A., Hottenga, J. J., de Geus, E., Morris, A. D., Palmer, C. N. A., Nolte, I. M., Milaneschi, Y., Marten, J., Wright, A., Zeggini, E., Howson, J. M. M., O'Donnell, C. J., Spector, T., Nalls, M. A., Simonsick, E. M., Liu, Y., van Duijn, C. M., Butterworth, A. S., Danesh, J. N., Menni, C., Wareham, N. J., Khaw, K. T., Sun, Y. V., Wilson, P. W. F., Cho, K., Visscher, P. M., Denny, J. C., Levy, D., Edwards, T. L., Munroe, P. B., Snieder, H. & Warren, H. R. Nat Genet 56, 778-791 (2024). https://pubmed.ncbi.nlm.nih.gov/38689001/
Long-term effectiveness and safety of edoxaban in patients with atrial fibrillation: 4-year data from the ETNA-AF-Europe study. Kirchhof, P., Bakhai, A., de Asmundis, C., de Groot, J. R., Deharo, J. C., Kelly, P., Lopez-de-Sa, E., Monteiro, P., Fronk, E. M., Lamparter, M., Laeis, P., Smolnik, R., Steffel, J., Waltenberger, J., Weiss, T. W. & De Caterina, R. Int J Cardiol 408, 132118 (2024). https://pubmed.ncbi.nlm.nih.gov/38697397/
Identification and outcomes of KDIGO-defined chronic kidney disease in 1.4 million U.S. Veterans with heart failure. Patel, S. S., Raman, V. K., Zhang, S., Deedwania, P., Zeng-Treitler, Q., Wu, W. C., Lam, P. H., Bakris, G., Moore, H., Heidenreich, P. A., Rangaswami, J., Morgan, C. J., Cheng, Y., Sheriff, H. M., Faselis, C., Mehta, R. L., Anker, S. D., Fonarow, G. C. & Ahmed, A. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38700246/
Neurological affection and serum neurofilament light chain in wild type transthyretin amyloidosis. Pernice, H. F., Knorz, A. L., Wetzel, P. J., Herrmann, C., Muratovic, H., Rieber, F., Asaad, E., Fiß, G., Barzen, G., Blüthner, E., Knebel, F., Spethmann, S., Messroghli, D., Heidecker, B., Brand, A., Wetz, C., Tschöpe, C. & Hahn, K. Sci Rep 14, 10111 (2024). https://pubmed.ncbi.nlm.nih.gov/38698025/
A Simple Bleeding Risk Score for the Complex Older Patient. Simonetti, F. & Kastrati, A. Am J Cardiol 223, 178-180 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38697452
Under pressure: Advances in device-based heart failure therapy for patients with preserved or mildly reduced ejection fraction. Stolz, L. & Hausleiter, J. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38700488/
Fostering healthy aging through selective nutrition: A long-term comparison of two dietary patterns and their holistic impact on mineral status in middle-aged individuals-A randomized controlled intervention trial in Germany. Pellowski, D., Heinze, T., Tuchtenhagen, M., Muller, S. M., Meyer, S., Maares, M., Gerbracht, C., Wernicke, C., Haase, H., Kipp, A. P., Grune, T., Pfeiffer, A. F. H., Mai, K. & Schwerdtle, T. J Trace Elem Med Biol 84, 127462 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38701651
Cardiac Computed Tomography Screening for Tricuspid Transcatheter Annuloplasty Implantation. Barbieri, F., Niehues, S. M., Feuchtner, G. M., Skurk, C., Landmesser, U., Polak-Krasna, K., Dreger, H., Kasner, M. & Reinthaler, M. Circ Cardiovasc Imaging, e016292 (2024). https://pubmed.ncbi.nlm.nih.gov/38708594/
Transcatheter aortic valve implantation in a patient with the left coronary artery originating directly above the annulus: images in cardiology. Lee, C. B., Hinkov, H., Dreger, H., Klein, C. & Unbehaun, A. Eur Heart J Case Rep 8, ytae212 (2024). https://pubmed.ncbi.nlm.nih.gov/38707524/
Testosterone and the risk of incident atrial fibrillation in older men: further analysis of the ASPREE study. Tran, C., Yeap, B. B., Ball, J., Clayton-Chubb, D., Hussain, S. M., Brodtmann, A., Tonkin, A. M., Neumann, J. T., Schneider, H. G., Fitzgerald, S., Woods, R. L. & McNeil, J. J. EClinicalMedicine 72, 102611 (2024). https://pubmed.ncbi.nlm.nih.gov/38707912/
Critical aortic stenosis - The long-term burden. Voges, I. & Hansen, J. H. Int J Cardiol 408, 132134 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38705208
Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression. Lozano-Vidal, N., Stanicek, L., Bink, D. I., Juni, R. P., Hooglugt, A., Kremer, V., Phelp, P., van Bergen, A., MacInnes, A. W., Dimmeler, S. & Boon, R. A. Commun Biol7, 541 (2024). https://pubmed.ncbi.nlm.nih.gov/38714838/
Angiotensin-(1-12): Does It Exist? A Critical Evaluation in Humans, Rats, and Mice. Rodrigues, A. F., Domenig, O., Poglitsch, M., Bader, M. & Danser, A. H. J. Hypertension81, 1776-1784 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38716648
Cardiac biomarkers for diagnosing Takotsubo syndrome. Schweiger, V., Di Vece, D., Cammann, V. L., Koleva, I., Wurdinger, M., Gilhofer, T., Rajman, K., Szawan, K. A., Niederseer, D., Citro, R., Vecchione, C., Bossone, E., Gili, S., Neuhaus, M., Franke, J., Meder, B., Jaguszewski, M., Noutsias, M., Knorr, M., Jansen, T., D'Ascenzo, F., Bruno, F., De Filippo, O., Stefanini, G., Campo, G., Wanha, W., Raposeiras Roubin, S., Dichtl, W., von Lewinski, D., Burgdorf, C., Kherad, B., Tschope, C., Sarcon, A., Shinbane, J., Rajan, L., Michels, G., Pfister, R., Cuneo, A., Jacobshagen, C., Karakas, M., Koenig, W., Pott, A., Meyer, P., Roffi, M., Banning, A., Wolfrum, M., Cuculi, F., Kobza, R., Fischer, T. A., Vasankari, T., Airaksinen, K. E. J., Napp, L. C., Dworakowski, R., MacCarthy, P., Kaiser, C., Osswald, S., Galiuto, L., Chan, C., Bridgman, P., Beug, D., Delmas, C., Lairez, O., Gilyarova, E., Shilova, A., Gilyarov, M., El-Battrawy, I., Akin, I., Polednikova, K., Tousek, P., Winchester, D. E., Massoomi, M., Galuszka, J., Ukena, C., Poglajen, G., Carrilho-Ferreira, P., Hauck, C., Paolini, C., Bilato, C., Kobayashi, Y., Kato, K., Ishibashi, I., Himi, T., Din, J., Al-Shammari, A., Prasad, A., Rihal, C. S., Liu, K., Schulze, P. C., Bianco, M., Jorg, L., Rickli, H., Pestana, G., Nguyen, T. H., Bohm, M., Maier, L. S., Pinto, F. J., Widimsky, P., Felix, S. B., Braun-Dullaeus, R. C., Rottbauer, W., Hasenfuss, G., Pieske, B. M., Schunkert, H., Budnik, M., Opolski, G., Thiele, H., Bauersachs, J., Horowitz, J. D., Di Mario, C., Kong, W., Dalakoti, M., Imori, Y., Munzel, T., Bax, J. J., Luscher, T. F., Crea, F., Ruschitzka, F., Ghadri, J. R. & Templin, C. Eur Heart J 45, 2254-2258 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38717630
Anticoagulation in COVID-19 patients - An updated systematic review and meta-analysis. Reis, S., Faske, A., Monsef, I., Langer, F., Müller, O. J., Kranke, P., Meybohm, P. & Weibel, S. Thromb Res 238, 141-150 (2024). https://pubmed.ncbi.nlm.nih.gov/38718472/
Influence of tricuspid regurgitation on the prognosis of patients with cardiogenic shock. Ruka, M., Schupp, T., Weidner, K., Egner-Walter, S., Forner, J., Mashayekhi, K., Tajti, P., Ayoub, M., Akin, M., Behnes, M., Akin, I. & Rusnak, J. Curr Med Res Opin, 1-16 (2024). https://pubmed.ncbi.nlm.nih.gov/38720658/
Repeated Injection of Very Small Superparamagnetic Iron Oxide Particles (VSOPs) in Murine Atherosclerosis: A Safety Study. Haase, T., Ludwig, A., Stach, A., Mohtashamdolatshahi, A., Hauptmann, R., Mundhenk, L., Kratz, H., Metzkow, S., Kader, A., Freise, C., Mueller, S., Stolzenburg, N., Radon, P., Liebl, M., Wiekhorst, F., Hamm, B., Taupitz, M. & Schnorr, J. Nanomaterials (Basel)14 (2024). https://pubmed.ncbi.nlm.nih.gov/38727367/
Pacemaker Channels and the Chronotropic Response in Health and Disease. Hennis, K., Piantoni, C., Biel, M., Fenske, S. & Wahl-Schott, C. Circ Res 134, 1348-1378 (2024). https://pubmed.ncbi.nlm.nih.gov/38723033/
Detectable troponin below the 99(th) percentile predicts survival in patients undergoing coronary angiography. Michel, L., Jehn, S., Dykun, I., Anker, M. S., Ferdinandy, P., Dobrev, D., Rassaf, T., Mahabadi, A. A. & Totzeck, M. Int J Cardiol Heart Vasc 52, 101419 (2024). https://pubmed.ncbi.nlm.nih.gov/38725439/
The Rise of T2. Nagel, E. & Pappas, L. JACC Cardiovasc Imaging (2024). https://pubmed.ncbi.nlm.nih.gov/38727645/
TPT-004, a Next-Generation Inhibitor of Tryptophan Hydroxylase, Ameliorates Pulmonary Arterial Hypertension in Rats. Wesolowski, R., Pleimes, D., Specker, E. & Bader, M. J Am Heart Assoc, e034240 (2024). https://pubmed.ncbi.nlm.nih.gov/38726898/
Poor Decision Making and Sociability Impairment Following Central Serotonin Reduction in Inducible TPH2-Knockdown Rats. Alonso, L., Peeva, P., Fernández-Del Valle Alquicira, T., Erdelyi, N., Gil Nolskog, Á., Bader, M., Winter, Y., Alenina, N. & Rivalan, M. Int J Mol Sci 25 (2024). https://pubmed.ncbi.nlm.nih.gov/38732220/
Antiplatelet Effects of Flavonoid Aglycones Are Mediated by Activation of Cyclic Nucleotide-Dependent Protein Kinases. Balykina, A., Naida, L., Kirkgöz, K., Nikolaev, V. O., Fock, E., Belyakov, M., Whaley, A., Whaley, A., Shpakova, V., Rukoyatkina, N. & Gambaryan, S. Int J Mol Sci 25 (2024). https://pubmed.ncbi.nlm.nih.gov/38732081/
Misleading Impact of Mitral Regurgitation on the Evaluation of Left Ventricular Contractile Function in Heart Failure With Preserved Ejection Fraction. Dandel, M. J Card Fail 30, 1065-1066 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38729559
The Ascyrus Medical Dissection Stent: A One-Fits-All Strategy for the Treatment of Acute Type A Aortic Dissection? Pitts, L., Moon, M. C., Luehr, M., Kofler, M., Montagner, M., Sündermann, S., Buz, S., Starck, C., Falk, V. & Kempfert, J. J Clin Med 13 (2024). https://pubmed.ncbi.nlm.nih.gov/38731123/
The complexities of modeling lifetime risk in the general population. Bahls, M. & Groß, S. Eur J Prev Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38736304/
Updated 2022 ACC/AHA Guideline Improves Concordance Between TTE and CT in Monitoring Marfan Snydrome and Related Disorders, but Relevant Measurement Differences Remain Frequent. Kolck, J., Trippel, T. D., Philipp, K., Gehle, P., Geisel, D. & Beetz, N. L. Glob Heart 23, 28 (2024). https://pubmed.ncbi.nlm.nih.gov/38737456/
Comparison of cardiac output estimates obtained from the Antares oscillometric pulse wave analysis algorithm and from Doppler transthoracic echocardiography. Stäuber, A., Hoppe, M. W., Lapp, H., Richter, S., Ohlow, M. A., Dörr, M., Piper, C., Eckert, S., Coll-Barroso, M. T., Stäuber, F., Abanador-Kamper, N. & Baulmann, J. PLoS One 19, e0302793 (2024). https://pubmed.ncbi.nlm.nih.gov/38739601/
What we claim to do and what we really do - a discrepancy in heart failure treatment. Assmus, B. & Sossalla, S. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38740572/
Incidence and pattern of urgent revascularization in acute coronary syndromes treated with ticagrelor or prasugrel. Aytekin, A., Scalamogna, M., Coughlan, J. J., Lahu, S., Ndrepepa, G., Menichelli, M., Mayer, K., Wohrle, J., Bernlochner, I., Witzenbichler, B., Hochholzer, W., Sibbing, D., Angiolillo, D. J., Hemetsberger, R., Tolg, R., Valina, C., Muller, A., Kufner, S., Liebetrau, C., Xhepa, E., Hapfelmeier, A., Sager, H. B., Joner, M., Richardt, G., Laugwitz, K. L., Neumann, F. J., Schunkert, H., Schupke, S., Kastrati, A. & Cassese, S. Clin Res Cardiol113, 1060-1069 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38740722
[Arrhythmias and amyloidosis]. Papathanasiou, M., Schlender, L. S., Johnson, V. L. & Wakili, R. Herzschrittmacherther Elektrophysiol (2024). https://pubmed.ncbi.nlm.nih.gov/38740607/
From rare events to systematic data collection: the RESCUED registry for sudden cardiac death in the young in Germany. Barkauskas, R., Jenewein, T., Scheiper-Welling, S., Wilmes, V., Niess, C., Petzel-Witt, S., Reitz, A., Gradhand, E., Falagkari, A., Papathanasiou, M., Wakili, R., Leistner, D. M., Vasseur, J., Göbel, J., Storf, H., Toennes, S. W., Kettner, M., Verhoff, M. A., Beckmann, B. M., Kauferstein, S. & Corvest, E. Clin Res Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38748206/
Oral microbiota of patients with phenylketonuria: A nation-based cross-sectional study. Bingol, M., Cardilli, A., Bingol, A. C., Lober, U., Bang, C., Franke, A., Bartzela, T., Beblo, S., Monch, E., Stolz, S., Schaefer, A. S., Forslund, S. K. & Richter, G. M. J Clin Periodontol 51, 1081-1092 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38745393
Sparse Group Penalties for bi-level variable selection. Buch, G., Schulz, A., Schmidtmann, I., Strauch, K. & Wild, P. S. Biom J 66, e2200334 (2024). https://pubmed.ncbi.nlm.nih.gov/38747086/
egr3 is a mechanosensitive transcription factor gene required for cardiac valve morphogenesis. da Silva, A. R., Gunawan, F., Boezio, G. L. M., Faure, E., Théron, A., Avierinos, J. F., Lim, S., Jha, S. G., Ramadass, R., Guenther, S., Looso, M., Zaffran, S., Juan, T. & Stainier, D. Y. R. Sci Adv 10, eadl0633 (2024). https://pubmed.ncbi.nlm.nih.gov/38748804/
Leaflet modification before transcatheter aortic valve implantation in patients at risk for coronary obstruction: the ShortCut study. Dvir, D., Tchétché, D., Leon, M. B., Généreux, P., Seguy, B., Makkar, R., Pibarot, P., Gada, H., Nazif, T., Hildick-Smith, D., Kempfert, J., Dumonteil, N., Unbehaun, A., Modine, T., Whisenant, B., Caussin, C., Conradi, L., Waggoner, T., Mishell, J. M., Chetcuti, S. J., Kar, S., Rinaldi, M. J., Szerlip, M., Ramana, R. K., Blackman, D. J., Ben-Dor, I., Kornowski, R., Waksman, R., Gerckens, U., Denti, P., Kukucka, M., Ternacle, J., Skaf, S., Kovac, J., Jilaihawi, H., Patel, V., Jubeh, R., Abdel-Wahab, M. & Kodali, S. Eur Heart J (2024). https://pubmed.ncbi.nlm.nih.gov/38747561/
Deactivation of LVAD Support for Myocardial Recovery - Surgical Perspectives. Nickel, I., Potapov, E., Sun, B., Zimpfer, D., Koliopoulou, A., Adachi, I., Anyanwu, A., Falk, V., Atluri, P., Faerber, G., Goldstein, D., Yarboro, L., Slaughter, M. S., Milano, C., Tsukashita, M., D'Alessandro, D., Silvestry, S., Kirov, H., Bommareddi, S., Lanmüller, P., Doenst, T. & Selzman, C. H. J Heart Lung Transplant (2024). https://pubmed.ncbi.nlm.nih.gov/38744354/
Ferritin Levels on Hospital Admission Predict Hypoxic-Ischemic Encephalopathy in Patients After Out-of-Hospital Cardiac Arrest: A Prospective Observational Single-Center Study. Nickelsen, S., Grosse Darrelmann, E., Seidlmayer, L., Fink, K., Britsch, S., Duerschmied, D., Scharf, R. E., Elsaesser, A. & Helbing, T. J Intensive Care Med, 8850666241252602 (2024). https://pubmed.ncbi.nlm.nih.gov/38748543/
[Xenotransplantation of solid organs]. Schmoeckel, M., Langin, M., Reichart, B., Abicht, J. M., Bender, M., Denner, J., Marckmann, G., Brenner, P., Wolf, E. & Hagl, C. Chirurgie (Heidelb)95, 603-609 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38748210
Right ventricular to pulmonary artery coupling in patients with different types of aortic stenosis undergoing TAVI. Steffen, J., Lux, M., Stocker, T. J., Kneidinger, N., Löw, K., Doldi, P. M., Haum, M., Fischer, J., Stolz, L., Theiss, H., Rizas, K., Braun, D., Orban, M., Peterß, S., Hausleiter, J., Massberg, S. & Deseive, S. Clin Res Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38748208/
Increased Expression of Inactive Rhomboid Protein 2 in Circulating Monocytes after Acute Myocardial Infarction. van Dijck, P., Hannemann, C., Dreger, H., Stangl, V., Stangl, K., Ludwig, A. & Hewing, B. J Cardiovasc Transl Res (2024). https://pubmed.ncbi.nlm.nih.gov/38743187/
Deep cardiac phenotyping by cardiovascular magnetic resonance reveals subclinical focal and diffuse myocardial injury in patients with psoriasis (PSOR-COR study). Gröschel, J., Grassow, L., Blaszczyk, E., Lommel, K., Kokolakis, G., Sabat, R. & Schulz-Menger, J. Clin Res Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38753001/
Streamlined Generation of CRISPR/Cas9-Mediated Single-Cell Knockout Clones in Murine Cell Lines. Hub, T., Cornean, A., Round, K., Fleming, T., Freichel, M. & Medert, R. ACS Pharmacol Transl Sci 7, 1291-1301 (2024). https://pubmed.ncbi.nlm.nih.gov/38751646/
Platelets: Orchestrators of immunity in host defense and beyond. Nicolai, L., Pekayvaz, K. & Massberg, S. Immunity 57, 957-972 (2024). https://pubmed.ncbi.nlm.nih.gov/38749398/
Pig models for translational Duchenne muscular dystrophy research. Stirm, M., Klymiuk, N., Nagashima, H., Kupatt, C. & Wolf, E. Trends Mol Med (2024). https://pubmed.ncbi.nlm.nih.gov/38749865/
Epicardial fat volume is associated with primary coronary slow-flow phenomenon in patients with severe aortic stenosis undergoing transcatheter valve implantation. Weferling, M., Rolf, A., Treiber, J., Fischer-Rasokat, U., Liebetrau, C., Hamm, C. W., Dey, D. & Kim, W. K. BMC Cardiovasc Disord 24, 253 (2024). https://pubmed.ncbi.nlm.nih.gov/38750455/
Inclisiran administration potently and durably lowers LDL-C over an extended-term follow-up: the ORION-8 trial. Wright, R. S., Raal, F. J., Koenig, W., Landmesser, U., Leiter, L. A., Vikarunnessa, S., Lesogor, A., Maheux, P., Talloczy, Z., Zang, X., Schwartz, G. G. & Ray, K. K. Cardiovasc Res (2024). https://pubmed.ncbi.nlm.nih.gov/38753448/
Age-related and species-specific methylation changes in the protein-coding marmoset sperm epigenome. Dittrich, M., Bernhardt, L., Penfold, C. A., Boroviak, T. E., Drummer, C., Behr, R., Müller, T. & Haaf, T. Aging Cell, e14200 (2024). https://pubmed.ncbi.nlm.nih.gov/38757354/
Inclisiran in individuals with diabetes or obesity: Post hoc pooled analyses of the ORION-9, ORION-10 and ORION-11 Phase 3 randomized trials. Leiter, L. A., Raal, F. J., Schwartz, G. G., Koenig, W., Ray, K. K., Landmesser, U., Han, J., Conde, L. G. & Wright, R. S. Diabetes Obes Metab 26, 3223-3237 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38757725
Photoinduced C-H arylation of 1,3-azoles via copper/photoredox dual catalysis. Trienes, S., Xu, J. & Ackermann, L. Chem Sci 15, 7293-7299 (2024). https://pubmed.ncbi.nlm.nih.gov/38756807/
Electrocardiographic Risk Stratification in Primary Prophylactic Implantable Cardioverter Defibrillator Patients: Can Future Arrhythmias Correlating with Sudden Cardiac Death Be Predicted? Zabel, M. & Friede, T. Europace (2024). https://pubmed.ncbi.nlm.nih.gov/38758091/
OCT-Guided versus Angiography-Guided Coronary Stent Implantation in Complex Lesions: An ILUMIEN IV Substudy. Ali, Z. A., Landmesser, U., Maehara, A., Shin, D., Sakai, K., Matsumura, M., Shlofmitz, R. A., Leistner, D., Canova, P., Alfonso, F., Fabbiocchi, F., Guagliumi, G., Price, M. J., Hill, J. M., Akasaka, T., Prati, F., Bezerra, H. G., Wijns, W., McGreevy, R. J., McNutt, R. W., Nie, H., Phalakornkule, K., Buccola, J. & Stone, G. W. J Am Coll Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38759907/
Full-Moon Coronary Calcification as Detected With Computed Tomography Angiography in Chronic Total Occlusion Percutaneous Coronary Intervention. Panuccio, G., Werner, G. S., De Rosa, S., Torella, D., Leistner, D. M., Siegrist, P. T., Haghikia, A., Skurk, C., Mashayekhi, K., Landmesser, U. & Abdelwahed, Y. S. Am J Cardiol 222, 149-156 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38761964
Procedural and clinical outcomes of patients undergoing a TAVI in TAVI procedure: Rationale and design of the multicentre, prospective, observational ReTAVI registry. Parma, R., Joner, M., Saia, F., Cuisset, T., Delgado, V., Rodes-Cabau, J., Modine, T., Van Belle, E., Fovino, L. N., Landes, U., Abdel-Wahab, M., Zamorano, J. L., Eden, M., Cademartiri, F., Skipirzepa, J. N., Kurucova, J., Greinert, D., Bramlage, P. & Tarantini, G. Eur J Clin Invest, e14241 (2024). https://pubmed.ncbi.nlm.nih.gov/38767226/
"Loss of landing zone"-Stabilizing endovascular treatment solutions in the aortic arch after thoracic endovascular aortic repair. Radner, C., Pichlmaier, M. A., Stana, J., Buech, J., Hagl, C., Tsilimparis, N. & Peterss, S. J Vasc Surg Cases Innov Tech 10, 101498 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38764463
Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats. Steinfeldt, J., Wild, B., Buergel, T., Pietzner, M., Upmeier Zu Belzen, J., Vauvelle, A., Hegselmann, S., Denaxas, S., Hemingway, H., Langenberg, C., Landmesser, U., Deanfield, J. & Eils, R. Nat Commun 15, 4257 (2024). https://pubmed.ncbi.nlm.nih.gov/38763986/
Commissural alignment and the ACURATE neo2 transcatheter aortic valve: Impact on valve performance. Travieso, A., Toggweiler, S., Montarello, N., Renker, M., Tirado-Conte, G., Loretz, L., Charitos, E. I., Kim, W. K. & De Backer, O. Catheter Cardiovasc Interv104, 115-124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38764320
Development of a long noncoding RNA-based machine learning model to predict COVID-19 in-hospital mortality. Devaux, Y., Zhang, L., Lumley, A. I., Karaduzovic-Hadziabdic, K., Mooser, V., Rousseau, S., Shoaib, M., Satagopam, V., Adilovic, M., Srivastava, P. K., Emanueli, C., Martelli, F., Greco, S., Badimon, L., Padro, T., Lustrek, M., Scholz, M., Rosolowski, M., Jordan, M., Brandenburger, T., Benczik, B., Agg, B., Ferdinandy, P., Vehreschild, J. J., Lorenz-Depiereux, B., Dörr, M., Witzke, O., Sanchez, G., Kul, S., Baker, A. H., Fagherazzi, G., Ollert, M., Wereski, R., Mills, N. L. & Firat, H. Nat Commun 15, 4259 (2024). https://pubmed.ncbi.nlm.nih.gov/38769334/
Nocturnal heat exposure and stroke risk. He, C., Breitner, S., Zhang, S., Huber, V., Naumann, M., Traidl-Hoffmann, C., Hammel, G., Peters, A., Ertl, M. & Schneider, A. Eur Heart J 45, 2158-2166 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38768958
Association of atrial mechanical dispersion with atrial fibrillation recurrence following catheter ablation: results of the ASTRA-AF pilot study. Knappe, D., Vogler, J., Weimann, J., Banas, V., Yildirim, S., Memenga, F., Senftinger, J., Keil, L., Ismaili, D., Nies, M., Rillig, A., Willems, S., Blankenberg, S., Kirchhof, P., Metzner, A. & Sinning, C. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38771346
Cortico-limbic restructuring and atherosclerosis: a stressful liaison. Mohanta, S. K., Santovito, D. & Weber, C. Eur Heart J 45, 1765-1767 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38770964
Effect of SGLT2 inhibitors on heart failure outcomes and cardiovascular death across the cardiometabolic disease spectrum: a systematic review and meta-analysis. Usman, M. S., Bhatt, D. L., Hameed, I., Anker, S. D., Cheng, A. Y. Y., Hernandez, A. F., Jones, W. S., Khan, M. S., Petrie, M. C., Udell, J. A., Friede, T. & Butler, J. Lancet Diabetes Endocrinol 12, 447-461 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38768620
Cardiomyocyte-specific RXFP1 overexpression protects against pressure overload-induced cardiac dysfunction independently of relaxin. Wingert, J., Meinhardt, E., Sasipong, N., Pott, M., Lederer, C., de la Torre, C., Sticht, C., Most, P., Katus, H. A., Frey, N., Raake, P. W. J. & Schlegel, P. Biochem Pharmacol 225, 116305 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38768763
Cardiovascular and genetic determinants of platelet high responsiveness: results from the Gutenberg Health Study. Baidildinova, G., Ten Cate, V., Panova-Noeva, M., Dahlen, B., Gieswinkel, A., von Ungern-Sternberg, S., Rapp, S., Strauch, K., Beutel, M. E., Pfeiffer, N., Lackner, K. J., Munzel, T., Ten Cate, H., Wild, P. S. & Jurk, K. Blood Adv 8, 3870-3874 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38776438
Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes. Bradfeld, J. P., Kember, R. L., Ulrich, A., Balkhiyarova, Z., Alyass, A., Aris, I. M., Bell, J. A., Broadaway, K. A., Chen, Z., Chai, J. F., Davies, N. M., Fernandez-Orth, D., Bustamante, M., Fore, R., Ganguli, A., Heiskala, A., Hottenga, J. J., Iniguez, C., Kobes, S., Leinonen, J., Lowry, E., Lyytikainen, L. P., Mahajan, A., Pitkanen, N., Schnurr, T. M., Have, C. T., Strachan, D. P., Thiering, E., Vogelezang, S., Wade, K. H., Wang, C. A., Wong, A., Holm, L. A., Chesi, A., Choong, C., Cruz, M., Elliott, P., Franks, S., Frithiof-Bojsoe, C., Gauderman, W. J., Glessner, J. T., Gilsanz, V., Griesman, K., Hanson, R. L., Kaakinen, M., Kalkwarf, H., Kelly, A., Kindler, J., Kahonen, M., Lanca, C., Lappe, J., Lee, N. R., McCormack, S., Mentch, F. D., Mitchell, J. A., Mononen, N., Niinikoski, H., Oken, E., Pahkala, K., Sim, X., Teo, Y. Y., Baier, L. J., van Beijsterveldt, T., Adair, L. S., Boomsma, D. I., de Geus, E., Guxens, M., Eriksson, J. G., Felix, J. F., Gilliland, F. D., Penn Medicine, B., Hansen, T., Hardy, R., Hivert, M. F., Holm, J. C., Jaddoe, V. W. V., Jarvelin, M. R., Lehtimaki, T., Mackey, D. A., Meyre, D., Mohlke, K. L., Mykkanen, J., Oberfeld, S., Pennell, C. E., Perry, J. R. B., Raitakari, O., Rivadeneira, F., Saw, S. M., Sebert, S., Shepherd, J. A., Standl, M., Sorensen, T. I. A., Timpson, N. J., Torrent, M., Willemsen, G., Hypponen, E., Power, C., Early Growth Genetics, C., McCarthy, M. I., Freathy, R. M., Widen, E., Hakonarson, H., Prokopenko, I., Voight, B. F., Zemel, B. S., Grant, S. F. A. & Cousminer, D. L. Genome Biol 25, 129 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38773652
Pulsed field ablation in patients with cardiac implantable electronic devices: an ex vivo assessment of safety. Lennerz, C., O'Connor, M., Schaarschmidt, C., Reents, T., Bourier, F., Telishevska, M., Lengauer, S., Popa, M., Wimbauer, K., Holmgren, E., Thoma, M., Spitzauer, L., Bahlke, F., Krafft, H., Englert, F., Knoll, K., Friedrich, L., Blazek, P., Hessling, G., Kolb, C., Deisenhofer, I. & Kottmaier, M. J Interv Card Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38775921
Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation. Pavlaki, N., Froese, A., Li, W., De Jong, K. A., Geertz, B., Subramanian, H., Mohagaonkar, S., Luo, X., Schubert, M., Wiegmann, R., Margaria, J. P., Ghigo, A., Kammerer, S., Hirsch, E., El-Armouche, A., Guan, K. & Nikolaev, V. O. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38776406
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Pekayvaz, K., Losert, C., Knottenberg, V., Gold, C., van Blokland, I. V., Oelen, R., Groot, H. E., Benjamins, J. W., Brambs, S., Kaiser, R., Gottschlich, A., Hoffmann, G. V., Eivers, L., Martinez-Navarro, A., Bruns, N., Stiller, S., Akgol, S., Yue, K., Polewka, V., Escaig, R., Joppich, M., Janjic, A., Popp, O., Kobold, S., Petzold, T., Zimmer, R., Enard, W., Saar, K., Mertins, P., Huebner, N., van der Harst, P., Franke, L. H., van der Wijst, M. G. P., Massberg, S., Heinig, M., Nicolai, L. & Stark, K. Nat Med 30, 1696-1710 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38773340
In vivo fluid dynamics of the Ventura interatrial shunt device in patients with heart failure. Pfeiffer, M., Boehmer, J., Gorcsan, J., Eguchi, S., Orihara, Y., Perl, M. L., Eigler, N., Abraham, W. T., Villota, J. N., Lee, E., Bayes-Genis, A., Moravsky, G., Kar, S., Zile, M. R., Holcomb, R., Anker, S. D., Stone, G. W., Rodes-Cabau, J., Lindenfeld, J. & Bax, J. J. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38773938
Heart's hidden battle: understanding Erdheim-Chester disease. Sato, R., Czepluch, F. & von Haehling, S. Heart 110, 885-886 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38772575
Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia. Weinberger, T., Denise, M., Joppich, M., Fischer, M., Garcia Rodriguez, C., Kumaraswami, K., Wimmler, V., Ablinger, S., Rauber, S., Fang, J., Liu, L., Liu, W. H., Winterhalter, J., Lichti, J., Thomas, L., Esfandyari, D., Percin, G., Matin, S., Hidalgo, A., Waskow, C., Engelhardt, S., Todica, A., Zimmer, R., Pridans, C., Gomez Perdiguero, E. & Schulz, C. Elife 12 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38775664
Mechanical circulatory support in patients with congenital heart disease: a European Registry for Patients with Mechanical Circulatory Support (EUROMACS) study. Ardissino, M., Morley, A. P., Lewis, C., Bhagra, C., Stoll, V., Popatov, E., Schoenrath, F., Gummert, J., Przybylowski, P., Sliwka, J., Meyns, B., de By, T., Jones, N. & Tsui, S. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38781499
Impact of empagliflozin on first and recurrent events leading to or prolonging hospitalisation in the EMPA-REG OUTCOME trial. Inzucchi, S. E., Wanner, C., Fitchett, D., Zinman, B., Anker, S. D., Pocock, S. J., Mattheus, M., Hantel, S. & Lund, S. S. Diabetes Res Clin Pract 212, 111715 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38777127
Lack of Formyl-peptide Receptor 1 Mitigates Atherosclerosis in Hyperlipidemic Mice. Doring, Y., Bender, A. & Soehnlein, O. Thromb Haemost (2024). https://www.ncbi.nlm.nih.gov/pubmed/38782024
Differences in presentation, diagnosis and management of heart failure in women. A scientific statement of the Heart Failure Association of the ESC. Rosano, G. M. C., Stolfo, D., Anderson, L., Abdelhamid, M., Adamo, M., Bauersachs, J., Bayes-Genis, A., Bohm, M., Chioncel, O., Filippatos, G., Hill, L., Lainscak, M., Lambrinou, E., Maas, A., Massouh, A. R., Moura, B., Petrie, M. C., Rakisheva, A., Ray, R., Savarese, G., Skouri, H., Van Linthout, S., Vitale, C., Volterrani, M., Metra, M. & Coats, A. J. S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783694
Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling. Schoger, E., Bleckwedel, F., Germena, G., Rocha, C., Tucholla, P., Sobitov, I., Mobius, W., Sitte, M., Lenz, C., Samak, M., Hinkel, R., Varga, Z. V., Giricz, Z., Salinas, G., Gross, J. C. & Zelarayan, L. C. Commun Biol 7, 624 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783104
Ca(V)1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy. Schwenzer, N., Teiwes, N. K., Kohl, T., Pohl, C., Giller, M. J., Lehnart, S. E. & Steinem, C. Commun Biol 7, 620 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783117
Human induced pluripotent stem cell-derived atrial cardiomyocytes recapitulate contribution of the slowly activating delayed rectifier currents IKs to repolarization in the human atrium. Sonmez, M. I., Goldack, S., Nurkkala, E., Schulz, C., Klampe, B., Schulze, T., Hansen, A., Eschenhagen, T., Koivumaki, J. & Christ, T. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38788213
Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series. Yule, M. S., Thompson, J., Leesahatsawat, K., Sousa, M. S., Anker, S. D., Arends, J., Balstad, T. R., Brown, L. R., Bye, A., Dajani, O., Fallon, M., Hjermstad, M. J., Jakobsen, G., McDonald, J., McGovern, J., Roeland, E. J., Sayers, J., Skipworth, R. J. E., Ottestad, I. O., Philips, I., Simpson, M. R., Solheim, T. S., Vagnildhaug, O. M., McMillan, D., Laird, B. J. A., Dolan, R. D. & Cancer Cachexia Endpoints Working, G. J Cachexia Sarcopenia Muscle15, 853-867 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783477
Left Atrial Appendage Occlusion in Patients With Anticoagulation Failure vs Anticoagulation Contraindication. Aarnink, E. W., Maarse, M., Fierro, N., Mazzone, P., Beneduce, A., Tondo, C., Gasperetti, A., Pracon, R., Demkow, M., Zielinski, K., de Backer, O., Korsholm, K., Nielsen-Kudsk, J. E., Estevez-Loureiro, R., Caneiro-Queija, B., Benito-Gonzalez, T., Perez de Prado, A., Nombela-Franco, L., Salinas, P., Holmes, D., Almakadma, A. H., Berti, S., Romeo, M. R., Millan, X., Arzamendi, D., Alla, V. M., Agarwal, H., Eitel, I., Paitazoglou, C., Freixa, X., Cepas-Guillen, P., Chothia, R., Badejoko, S. O., Spoon, D. B., Maddux, J. T., El-Chami, M., Ram, P., Branca, L., Adamo, M., Suradi, H. S., Peper, J., van Dijk, V. F., Rensing, B., Swaans, M. J., Vireca, E., Bergmann, M. W., Boersma, L. V. A., Str-Oac, L. & Investigators, E. JACC Cardiovasc Interv 17, 1311-1321 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38795093
Comparison of interventional treatment options for coronary calcified nodules: A sub-analysis of the ROTA.shock trial. Blachutzik, F., Meier, S., Blachutzik, M., Schlattner, S., Gori, T., Ullrich-Daub, H., Gaede, L., Achenbach, S., Mollmann, H., Chitic, B., Aksoy, A., Nickenig, G., Weferling, M., Dorr, O., Boeder, N., Bayer, M., Hamm, C., Nef, H. & Investigators, R. O. s. Cardiovasc Revasc Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38796321
Stroke outcomes following durable left ventricular assist device implant in patients bridged with micro-axial flow pump: Insights from a large registry. Gallone, G., Lewin, D., Rojas Hernandez, S., Bernhardt, A., Billion, M., Meyer, A., Netuka, I., Kooij, J. J., Pieri, M., Szymanski, M. K., Moeller, C. H., Akhyari, P., Jawad, K., Krasivskyi, I., Schmack, B., Farber, G., Medina, M., Haneya, A., Zimpfer, D., Nersesian, G., Lanmueller, P., Spitaleri, A., Oezkur, M., Djordjevic, I., Saeed, D., Boffini, M., Stein, J., Gustafsson, F., Scandroglio, A. M., De Ferrari, G. M., Meyns, B., Hofmann, S., Belohlavek, J., Gummert, J., Rinaldi, M., Potapov, E. V. & Loforte, A. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/38803239
Safety and efficacy of the latest generation biodegradable polymer-coated ultrathin sirolimus-eluting stent in the treatment of coronary artery disease in a European all-comer population with or without high bleeding risk: The Cruz HBR Registry. Leistner, D. M., Rampat, R., Haude, M., Schmitz, T., Allali, A., Mollmann, H., Stahli, B. E., Rudolph, T. K., Lauten, A., Koning, R., Bogaerts, K., Sudhir, K. & Naber, C. Minerva Cardiol Angiol 72, 355-365 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38804621
New insights into the hypothalamic-pituitary-thyroid axis: a transcriptome- and proteome-wide association study. Monteiro-Martins, S., Sterenborg, R., Borisov, O., Scherer, N., Cheng, Y., Medici, M., Kottgen, A. & Teumer, A. Eur Thyroid J 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38805593
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Pelli, A., Kentta, T. V., Junttila, M. J., Huber, C., Schlogl, S., Zabel, M., Malik, M., Willems, R., Vos, M. A., Harden, M., Friede, T., Sticherling, C., Huikuri, H. V. & Investigators, E.-C.-I. S. J Am Heart Assoc 13, e032465 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38804218
2024 update in heart failure. Beghini, A., Sammartino, A. M., Papp, Z., von Haehling, S., Biegus, J., Ponikowski, P., Adamo, M., Falco, L., Lombardi, C. M., Pagnesi, M., Savarese, G., Metra, M. & Tomasoni, D. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38806171
Impact of malnutrition in patients with severe heart failure. Pagnesi, M., Serafini, L., Chiarito, M., Stolfo, D., Baldetti, L., Inciardi, R. M., Tomasoni, D., Adamo, M., Lombardi, C. M., Sammartino, A. M., Loiacono, F., Maccallini, M., Villaschi, A., Gasparini, G., Montella, M., Contessi, S., Cocianni, D., Perotto, M., Barone, G., Anker, S. D., Merlo, M., Cappelletti, A. M., Sinagra, G., Pini, D. & Metra, M. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38808603
Spontaneous coronary artery dissection - We are the patients. Senftinger, J., Poss, J. & Clemmensen, P. Eur Heart J Acute Cardiovasc Care (2024). https://www.ncbi.nlm.nih.gov/pubmed/38809768
Spontaneous coronary artery dissection: we are the patients. Senftinger, J., Poss, J. & Clemmensen, P. Eur Heart J Acute Cardiovasc Care 13, 521-522 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38809768
Atherosclerosis is an inflammatory disease: treat it as such! Therre, M., Wenzel, P. & Haring, B. Clin Res Cardiol 113, 1274-1275 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38806822
Identification of a functional missense variant in the matrix metallopeptidase 10 (MMP10) gene in two families with premature myocardial infarction. Verovenko, V., Tennstedt, S., Kleinecke, M., Kessler, T., Schunkert, H., Erdmann, J., Ensminger, S. & Aherrahrou, Z. Sci Rep 14, 12212 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38806571
Plasma proteome association with coronary heart disease and carotid intima media thickness: results from the KORA F4 study. Elhadad, M. A., Del, C. G.-A. M., Chen, C. W., Neumeyer, S., Delerue, T., Rathmann, W., Nabauer, M., Meisinger, C., Kaab, S., Seissler, J., Graumann, J., Koenig, W., Suhre, K., Gieger, C., Volker, U., Peters, A., Hammer, E. & Waldenberger, M. Cardiovasc Diabetol 23, 181 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38811951
Mediastinal transposition of the greater omentum for treatment of infected prostheses of the ascending aorta and aortic arch. Pitts, L., Pasic, M., Wert, L., Nersesian, G., Kaemmel, J., Buz, S., Knosalla, C., Dusterhoft, V., Starck, C., Kempfert, J., Jacobs, S. & Falk, V. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38814808
Residual tricuspid regurgitation after tricuspid transcatheter edge-to-edge repair: Insights into the EuroTR registry. Stolz, L., Kresoja, K. P., von Stein, J., Fortmeier, V., Koell, B., Rottbauer, W., Kassar, M., Goebel, B., Denti, P., Achouh, P., Rassaf, T., Barreiro-Perez, M., Boekstegers, P., Ruck, A., Doldi, P. M., Novotny, J., Zdanyte, M., Adamo, M., Vincent, F., Schlegel, P., von Bardeleben, R. S., Stocker, T. J., Weckbach, L. T., Wild, M. G., Brunner, S., Toggweiler, S., Grapsa, J., Patterson, T., Thiele, H., Kister, T., Konstandin, M. H., Van Belle, E., Metra, M., Geisler, T., Estevez-Loureiro, R., Luedike, P., Karam, N., Maisano, F., Lauten, P., Praz, F., Kessler, M., Kalbacher, D., Rudolph, V., Iliadis, C., Lurz, P., Hausleiter, J. & on behalf of the Euro, T. R. I. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38812292
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications. Bode, D., Pronto, J. R. D., Schiattarella, G. G. & Voigt, N. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38816507
Sex-specific ventricular morphology, function, and tissue characteristics in arterial hypertension: a magnetic resonance study of the Hamburg city health cohort. Erley, J., Jahnke, C. M., Schuttler, S., Molwitz, I., Chen, H., Meyer, M., Muellerleile, K., Cavus, E., Lund, G. K., Blankenberg, S., Adam, G. & Tahir, E. Eur Radiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38819515
Pulmonary 4D-flow MRI imaging in landrace pigs under rest and stress. Faragli, A., Hullebrand, M., Berendsen, A. J., Sola, L. T., Lo Muzio, F. P., Gotze, C., Tanacli, R., Doeblin, P., Stehning, C., Schnackenburg, B., Van der Vosse, F. N., Nagel, E., Post, H., Hennemuth, A., Alogna, A. & Kelle, S. Int J Cardiovasc Imaging 40, 1511-1524 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38819601
Microvascular dysfunction in heart transplantation is associated with altered cardiomyocyte mitochondrial structure and unimpaired excitation-contraction coupling. Hohendanner, F., Boegner, M., Huettemeister, J., Zhang, K., Dreysse, S., Knosalla, C., Falk, V., Schoenrath, F., Just, I. A. & Stawowy, P. PLoS One 19, e0303540 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38820336
Transcatheter heart valve explant with infective endocarditis-associated prosthesis failure and outcomes: the EXPLANT-TAVR international registry. Marin-Cuartas, M., Tang, G. H. L., Kiefer, P., Fukuhara, S., Lange, R., Harrington, K. B., Saha, S., Hagl, C., Kleiman, N. S., Goel, S. S., Kempfert, J., Werner, P., Petrossian, G. A., Geirsson, A., Desai, N. D., Chu, M. W. A., Bhadra, O. D., Shults, C., Garatti, A., Vincent, F., Grubb, K. J., Goldberg, J. B., Mack, M. J., Modine, T., Denti, P., Kaneko, T., Bapat, V. N., Reardon, M. J., Borger, M. A., Zaid, S. & Investigators, E.-T. Eur Heart J 45, 2519-2532 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38820201
Mitochondrial DNA variants and microbiota: An experimental strategy to identify novel therapeutic potential in chronic inflammatory diseases. Olbrich, M., Hartmann, A. M., Kunzel, S., Aherrahrou, Z., Schilf, P., Baines, J. F., Ibrahim, S. M. & Hirose, M. Pharmacol Res 205, 107231 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38815878
S100A1's single cysteine is an indispensable redox-switch for the protection against diastolic calcium wavesin cardiomyocytes. Seitz, A., Busch, M., Kroemer, J., Schneider, A., Simon, S., Jungmann, A., Katus, H. A., Most, P. & Ritterhoff, J. Am J Physiol Heart Circ Physiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38819384
April
Paper of the Month
Transcatheter or Surgical Treatment of Aortic-Valve Stenosis
DZHK authors: Stefan Blankenberg, Peter Clemmensen, Jochen Cremer, Nina Diercks, Ingo Eitel, Stephan Ensminger, Derk Frank, Inke R. König, Hermann Reichenspurner, Raphael Twerenbold, Christian Hagl, Markus Krane, Norbert Frey, Matthias Karck, Christian Hamm, Won-Keun Kim, Thomas Walther, Ulf Landmesser, Volkmar Falk. The New England Journal of Medicine.
Body mass index and cardiorenal outcomes in the EMPEROR-Preserved trial: Principal findings and meta-analysis with the DELIVER trial. Sattar, N., Butler, J., Lee, M. M. Y., Harrington, J., Sharma, A., Zannad, F., Filippatos, G., Verma, S., Januzzi, J. L., Ferreira, J. P., Pocock, S. J., Pfarr, E., Ofstad, A. P., Brueckmann, M., Packer, M. & Anker, S. D. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38558521
Impact of empagliflozin on insulin needs in patients with heart failure and diabetes: An EMPEROR-Pooled analysis. Talha, K. M., Green, J., Filippatos, G., Pocock, S., Zannad, F., Brueckmann, M., Schueler, E., Ofstad, A. P., Ferreira, J. P., Anker, S. D., Butler, J., Rosenstock, J. & Packer, M. Diabetes Obes Metab 26, 2578-2587 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38558314
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage. Tsvilovskyy, V., Ottenheijm, R., Kriebs, U., Schutz, A., Diakopoulos, K. N., Jha, A., Bildl, W., Wirth, A., Bock, J., Jaslan, D., Ferro, I., Taberner, F. J., Kalinina, O., Hildebrand, S., Wissenbach, U., Weissgerber, P., Vogt, D., Eberhagen, C., Mannebach, S., Berlin, M., Kuryshev, V., Schumacher, D., Philippaert, K., Camacho-Londono, J. E., Mathar, I., Dieterich, C., Klugbauer, N., Biel, M., Wahl-Schott, C., Lipp, P., Flockerzi, V., Zischka, H., Algul, H., Lechner, S. G., Lesina, M., Grimm, C., Fakler, B., Schulte, U., Muallem, S. & Freichel, M. J Clin Invest 134 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38557489
DLC1 promotes mechanotransductive feedback for YAP via RhoGAP-mediated focal adhesion turnover. Hooglugt, A., van der Stoel, M. M., Shapeti, A., Neep, B. F., de Haan, A., van Oosterwyck, H., Boon, R. A. & Huveneers, S. J Cell Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/38563084
Effect of liraglutide on thigh muscle fat and muscle composition in adults with overweight or obesity: Results from a randomized clinical trial. Pandey, A., Patel, K. V., Segar, M. W., Ayers, C., Linge, J., Leinhard, O. D., Anker, S. D., Butler, J., Verma, S., Joshi, P. H. & Neeland, I. J. J Cachexia Sarcopenia Muscle (2024). https://www.ncbi.nlm.nih.gov/pubmed/38561962
Interatrial shunt therapy in advanced heart failure: Outcomes from the open-label cohort of the RELIEVE-HF trial. Rodes-Cabau, J., Lindenfeld, J., Abraham, W. T., Zile, M. R., Kar, S., Bayes-Genis, A., Eigler, N., Holcomb, R., Nunez, J., Lee, E., Perl, M. L., Moravsky, G., Pfeiffer, M., Boehmer, J., Gorcsan, J., Bax, J. J., Anker, S. & Stone, G. W. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38561314
Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis. Tamiato, A., Tombor, L. S., Fischer, A., Muhly-Reinholz, M., Vanicek, L. R., Togru, B. N., Neitz, J., Glaser, S. F., Merten, M., Rodriguez Morales, D., Kwon, J., Klatt, S., Schumacher, B., Gunther, S., Abplanalp, W. T., John, D., Fleming, I., Wettschureck, N., Dimmeler, S. & Luxan, G. Circ Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38563133
Dapagliflozin and atrial fibrillation: elevated dosing to achieve class I antiarrhythmic effects? Christ, T., Schwedhelm, E. & Eschenhagen, T. Basic Res Cardiol (2024). www.ncbi.nlm.nih.gov/pubmed/38568224
Atrioventricular valve surgery in patients with univentricular heart and two separate atrioventricular valves. Mayr, B., Osawa, T., Staehler, H., Schaeffer, T., Rohlig, C., Cleuziou, J., Hager, A., Ewert, P., Horer, J., Lange, R. & Ono, M. Cardiol Young, 1-9 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38567959
Drivers and recent trends of hospitalisation costs related to acute pulmonary embolism. Mohr, K., Hobohm, L., Kaier, K., Farmakis, I. T., Valerio, L., Barco, S., Abele, C., Munzel, T., Neusius, T., Konstantinides, S., Binder, H. & Keller, K. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38565711
Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma. Yalcin, F., Haneke, H., Efe, I. E., Kuhrt, L. D., Motta, E., Nickl, B., Fluh, C., Synowitz, M., Dzaye, O., Bader, M. & Kettenmann, H. Acta Neuropathol Commun 12, 50 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38566120
mtDNA analysis using Mitopore. Dobner, J., Nguyen, T., Pavez-Giani, M. G., Cyganek, L., Distelmaier, F., Krutmann, J., Prigione, A. & Rossi, A. Mol Ther Methods Clin Dev 32, 101231 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38572068
Noise annoyance due to different sources is associated with tinnitus presence and distress in the general population. Hahad, O., Doge, J., Bahr-Hamm, K., Beutel, M. E., Kontohow-Beckers, K., Schuster, A. K., Keller, K., Hobohm, L., Schmitt, V. H., Gianicolo, E., Lackner, K. J., Daiber, A., Wild, P. S., Hackenberg, B. & Munzel, T. J Expo Sci Environ Epidemiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38570612
Mapping the interplay of immunoproteasome and autophagy in different heart failure phenotypes. Ott, C. Free Radic Biol Med 218, 149-165 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38570171
Congestion patterns in severe tricuspid regurgitation and transcatheter treatment: Insights from a multicentre registry. Rommel, K. P., Bonnet, G., Fortmeier, V., Stolz, L., Schober, A. R., von Stein, J., Kassar, M., Gercek, M., Rosch, S., Stocker, T. J., Korber, M. I., Kresoja, K. P., Rudolph, T. K., Pfister, R., Baldus, S., Windecker, S., Thiele, H., Praz, F., Hausleiter, J., Rudolph, V., Burkhoff, D. & Lurz, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38571456
Unravelling the molecular interplay: SUMOylation, PML nuclear bodies and vascular cell activity in health and disease. Berkholz, J. & Karle, W. Cell Signal 119, 111156 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38574938
Large-scale assessment of physical activity in a population using high-resolution hip-worn accelerometry: the German National Cohort (NAKO). Weber, A., van Hees, V. T., Stein, M. J., Gastell, S., Steindorf, K., Herbolsheimer, F., Ostrzinski, S., Pischon, T., Brandes, M., Krist, L., Marschollek, M., Greiser, K. H., Nimptsch, K., Brandes, B., Jochem, C., Sedlmeier, A. M., Berger, K., Brenner, H., Buck, C., Castell, S., Dorr, M., Emmel, C., Fischer, B., Flexeder, C., Harth, V., Hebestreit, A., Heise, J. K., Holleczek, B., Keil, T., Koch-Gallenkamp, L., Lieb, W., Meinke-Franze, C., Michels, K. B., Mikolajczyk, R., Kluttig, A., Obi, N., Peters, A., Schmidt, B., Schipf, S., Schulze, M. B., Teismann, H., Waniek, S., Willich, S. N., Leitzmann, M. F. & Baurecht, H. Sci Rep 14, 7927 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38575636
Mst4, a novel cardiac STRIPAK complex associated kinase, regulates cardiomyocyte growth and survival and is upregulated in human cardiomyopathy. Eden, M., Leye, M., Hahn, J., Heilein, E., Luzarowski, M., Volschow, B., Tannert, C., Sossalla, S., Lucena-Porcel, C., Frank, D. & Frey, N. J Biol Chem, 107255 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38579991
Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights from the EMPACT-MI Trial. Hernandez, A. F., Udell, J. A., Jones, W. S., Anker, S. D., Petrie, M. C., Harrington, J., Mattheus, M., Seide, S., Zwiener, I., Amir, O., Bahit, M. C., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V. K., Figtree, G., Ge, J., Goodman, S., Gotcheva, N., Goto, S., Gasior, T., Jamal, W., Januzzi, J. L., Jeong, M. H., Lopatin, Y., Lopes, R. D., Merkely, B., Parikh, P. B., Parkhomenko, A., Ponikowski, P., Rossello, X., Schou, M., Simic, D., Steg, P. G., Szachniewicz, J., van der Meer, P., Vinereanu, D., Zieroth, S., Brueckmann, M., Sumin, M., Bhatt, D. L. & Butler, J. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38581389
Pediatric Z-Score Calculator of Cardiac MRI Volumetric Measurements. Voges, I., Caliebe, A., Hinz, S., Daubeney, P., Boroni Gracioli, S., Mohiaddin, R. H., Uebing, A. S., Pennell, D. J., Gabbert, D. D. & Krupickova, S. J Magn Reson Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38580327
RNA-DNA triplexes: molecular mechanisms and functional relevance. Leisegang, M. S., Warwick, T., Stotzel, J. & Brandes, R. P. Trends Biochem Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/38582689
Sodium Glucose Co-transporter 2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Patel, S. M., Kang, Y. M., Im, K., Neuen, B. L., Anker, S. D., Bhatt, D. L., Butler, J., Cherney, D. Z. I., Claggett, B. L., Fletcher, R. A., Herrington, W. G., Inzucchi, S. E., Jardine, M. J., Mahaffey, K. W., McGuire, D. K., McMurray, J. J. V., Neal, B., Packer, M., Perkovic, V., Solomon, S. D., Staplin, N., Vaduganathan, M., Wanner, C., Wheeler, D. C., Zannad, F., Zhao, Y., Heerspink, H. J. L., Sabatine, M. S. & Wiviott, S. D. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38583093
Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON). Appel, K. S., Nurnberger, C., Bahmer, T., Forster, C., Polidori, M. C., Kohls, M., Kraus, T., Hettich-Damm, N., Petersen, J., Blaschke, S., Brohl, I., Butzmann, J., Dashti, H., Deckert, J., Dreher, M., Fiedler, K., Finke, C., Geisler, R., Hanses, F., Hopff, S. M., Jensen, B. O., Konik, M., Lehnert, K., de Miranda, S. M. N., Mitrov, L., Miljukov, O., Reese, J. P., Rohde, G., Scherer, M., Tausche, K., Tebbe, J. J., Vehreschild, J. J., Voit, F., Wagner, P., Weigl, M., Lemhofer, C. & Group, N. S. Infection (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587752
Transcatheter or Surgical Treatment of Aortic-Valve Stenosis. Blankenberg, S., Seiffert, M., Vonthein, R., Baumgartner, H., Bleiziffer, S., Borger, M. A., Choi, Y. H., Clemmensen, P., Cremer, J., Czerny, M., Diercks, N., Eitel, I., Ensminger, S., Frank, D., Frey, N., Hagendorff, A., Hagl, C., Hamm, C., Kappert, U., Karck, M., Kim, W. K., Konig, I. R., Krane, M., Landmesser, U., Linke, A., Maier, L. S., Massberg, S., Neumann, F. J., Reichenspurner, H., Rudolph, T. K., Schmid, C., Thiele, H., Twerenbold, R., Walther, T., Westermann, D., Xhepa, E., Ziegler, A., Falk, V. & Investigators, D.-D. T. N Engl J Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38588025
Insulin-like growth factor binding protein-7 concentrations in chronic heart failure: Results from the EMPEROR programme. Ferreira, J. P., Packer, M., Sattar, N., Butler, J., Gonzalez Maldonado, S., Panova-Noeva, M., Sumin, M., Masson, S., Pocock, S. J., Anker, S. D., Zannad, F. & Januzzi, J. L. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587259
Association of an impaired GH-IGF-I axis with cardiac wasting in patients with advanced cancer. Frohlich, A. K., Porthun, J., Talha, K. M., Lena, A., Hadzibegovic, S., Wilkenshoff, U., Sonntag, F., Nikolski, A., Ramer, L. V., Zeller, T., Keller, U., Bullinger, L., Anker, S. D., Haverkamp, W., von Haehling, S., Doehner, W., Rauch, U., Skurk, C., Cleland, J. G. F., Butler, J., Coats, A. J. S., Landmesser, U., Karakas, M. & Anker, M. S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587563
The role of coronary artery disease in lung transplantation: a propensity-matched analysis. Lusebrink, E., Gade, N., Seifert, P., Ceelen, F., Veit, T., Fohrer, F., Hoffmann, S., Hopler, J., Binzenhofer, L., Roden, D., Saleh, I., Lanz, H., Michel, S., Schneider, C., Irlbeck, M., Tomasi, R., Hatz, R., Hausleiter, J., Hagl, C., Magnussen, C., Meder, B., Zimmer, S., Luedike, P., Schafer, A., Orban, M., Milger, K., Behr, J., Massberg, S. & Kneidinger, N. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587564
Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation. Maurer, W., Rebs, S., Kohne, S., Eberl, H., Wollnik, B., Zibat, A. & Streckfuss-Bomeke, K. Stem Cell Res 77, 103409 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38583294
Lack of Laminar Shear Stress Facilitates the Endothelial Uptake of Very Small Superparamagnetic Iron Oxide Nanoparticles by Modulating the Endothelial Surface Layer. Twamley, S. G., Gimber, N., Sanchez-Ibarra, H. E., Christaller, T., Isakzai, V., Kratz, H., Mitra, R., Kampen, L., Stach, A., Heilmann, H., Sohl-Kielczynski, B., Ebong, E. E., Schmoranzer, J., Munster-Wandowski, A. & Ludwig, A. Int J Nanomedicine 19, 3123-3142 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38585474
Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation. Zhu, Y., Ackers-Johnson, M., Shanmugam, M. K., Pakkiri, L. S., Drum, C. L., Chen, Y., Kim, J., Paltzer, W. G., Mahmoud, A. I., Wen Tan, W. L., Lee, M. C. J., Jiang, J., Luu, D. A. T., Ng, S. L., Li, P. Y. Q., Wang, A., Qi, R., Ong, G. J. X., Ng Yu, T., Haigh, J. J., Tiang, Z., Richards, A. M. & Foo, R. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38586957
Spatial characteristics of non-communicable diseases and their associations to social conditions in a large urban cohort in Germany-Results from the Hamburg City Health Study. Andrees, V., Bei der Kellen, R., Augustin, M., Gallinat, J., Harth, V., Hoven, H., Kuhn, S., Lautenbach, A., Magnussen, C., Mohr, N., Twerenbold, R., Schafer, I., Waschki, B., Zyriax, B. C. & Augustin, J. PLoS One 19, e0301475 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38593150
Infection, inflammation, and cardiovascular risk: are we underestimating an old disease? Arnold, N. & Koenig, W. Eur Heart J (2024). www.ncbi.nlm.nih.gov/pubmed/38591639
An International Multicenter Cohort Study on Implantable Cardioverter Defibrillators for the Treatment of Symptomatic Children with Catecholaminergic Polymorphic Ventricular Tachycardia. Lamba, A., Roston, T. M., Peltenburg, P. J., Kallas, D., Franciosi, S., Lieve, K. V. V., Kannankeril, P. J., Horie, M., Ohno, S., Brugada, R., Aiba, T., Fischbach, P., Knight, L., Till, J., Kwok, S. Y., Probst, V., Backhoff, D., LaPage, M. J., Batra, A. S., Drago, F., Haugaa, K., Krahn, A. D., Robyns, T., Swan, H., Tavacova, T., Atallah, J., Borggrefe, M., Rudic, B., Sarquella-Brugada, G., Chorin, E., Hill, A., Kammeraad, J., Kamp, A., Law, I., Perry, J., Roberts, J. D., Tisma-Dupanovic, S., Semsarian, C., Skinner, J. R., Tfelt-Hansen, J., Denjoy, I., Leenhardt, A., Schwartz, P. J., Ackerman, M. J., Wilde, A. A. M., van der Werf, C. & Sanatani, S. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/38588993
Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference. Linz, D., Andrade, J. G., Arbelo, E., Boriani, G., Breithardt, G., Camm, A. J., Caso, V., Nielsen, J. C., De Melis, M., De Potter, T., Dichtl, W., Diederichsen, S. Z., Dobrev, D., Doll, N., Duncker, D., Dworatzek, E., Eckardt, L., Eisert, C., Fabritz, L., Farkowski, M., Filgueiras-Rama, D., Goette, A., Guasch, E., Hack, G., Hatem, S., Haeusler, K. G., Healey, J. S., Heidbuechel, H., Hijazi, Z., Hofmeister, L. H., Hove-Madsen, L., Huebner, T., Kaab, S., Kotecha, D., Malaczynska-Rajpold, K., Merino, J. L., Metzner, A., Mont, L., Ng, G. A., Oeff, M., Parwani, A. S., Puererfellner, H., Ravens, U., Rienstra, M., Sanders, P., Scherr, D., Schnabel, R., Schotten, U., Sohns, C., Steinbeck, G., Steven, D., Toennis, T., Tzeis, S., van Gelder, I. C., van Leerdam, R. H., Vernooy, K., Wadhwa, M., Wakili, R., Willems, S., Witt, H., Zeemering, S. & Kirchhof, P. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38591838
Oral anticoagulation in device-detected atrial fibrillation: effects of age, sex, cardiovascular comorbidities, and kidney function on outcomes in the NOAH-AFNET 6 trial. Lip, G. Y. H., Nikorowitsch, J., Sehner, S., Becher, N., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Beuger, V., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G. A., Dichtl, W., Diener, H. C., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A., Lubinski, A., Marijon, E., Merkely, B., Mont, L., Ozga, A. K., Rajappan, K., Sarkozy, A., Scherr, D., Schnabel, R. B., Schotten, U., Simantirakis, E., Toennis, T., Vardas, P., Wichterle, D., Zapf, A. & Kirchhof, P. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38591192
Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction. Udell, J. A., Petrie, M. C., Jones, W. S., Anker, S. D., Harrington, J., Mattheus, M., Seide, S., Amir, O., Bahit, M. C., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V. K., Figtree, G., Ge, J., Goodman, S. G., Gotcheva, N., Goto, S., Gasior, T., Jamal, W., Januzzi, J. L., Jeong, M. H., Lopatin, Y., Lopes, R. D., Merkely, B., Martinez-Traba, M., Parikh, P. B., Parkhomenko, A., Ponikowski, P., Rossello, X., Schou, M., Simic, D., Steg, P. G., Szachniewicz, J., van der Meer, P., Vinereanu, D., Zieroth, S., Brueckmann, M., Sumin, M., Bhatt, D. L., Hernandez, A. F. & Butler, J. J Am Coll Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38588929
Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction. Wang, T., Shao, J., Kumar, S., Alnouri, M. W., Carvalho, J., Gunther, S., Krasel, C., Murphy, K. T., Bunemann, M., Offermanns, S. & Wettschureck, N. Circ Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38597112
Paradox of disproportionate atrial functional mitral regurgitation and survival after transcatheter edge-to-edge repair. Doldi, P. M., Stolz, L., Kassar, M., Kalbacher, D., Petronio, A. S., Butter, C., von Bardeleben, R. S., Iliadis, C., Grayburn, P. & Hausleiter, J. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38602287
Caught in action: how MSCs modulate atherosclerotic plaque. Egea, V. Front Cell Dev Biol 12, 1379091 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38601079
Mitral Valve Transcatheter Edge-to-Edge Repair: 1-Year Outcomes From the MiCLASP Study. Lurz, P., Schmitz, T., Geisler, T., Hausleiter, J., Eitel, I., Rudolph, V., Lubos, E., von Bardeleben, R. S., Brambilla, N., De Marco, F., Berti, S., Nef, H., Linke, A., Hengstenberg, C., Baldus, S., Spargias, K., Denti, P., Nickenig, G., Mollmann, H., Rottbauer, W., Praz, F., Butter, C., Reinthaler, M., Van Mieghem, N. M., Sherif, M., Swaans, M., Witkowski, A., Buch, M., Seidler, T., Iniguez, A., Thiele, H., Eissmann, M., Schreieck, J., Nabauer, M., Marcoff, L., Koulogiannis, K., Rassaf, T., Luedike, P. & Mi, C. S. I. JACC Cardiovasc Interv 17, 890-903 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38599692
Parenchymal cues define Vegfa-driven venous angiogenesis by activating a sprouting competent venous endothelial subtype. Preau, L., Lischke, A., Merkel, M., Oegel, N., Weissenbruch, M., Michael, A., Park, H., Gradl, D., Kupatt, C. & le Noble, F. Nat Commun 15, 3118 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38600061
Characteristics associated with occurrence of stroke in patients with infective endocarditis - a retrospective cohort study. Schuermann, H., von Rennenberg, R., Riegler, C., Rangus, I., Litmeier, S., Scheitz, J. F., Doehner, W., Audebert, H., Braemswig, T. B. & Nolte, C. H. Neurol Res Pract 6, 22 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38600573
Modulation of Antiplatelet Therapy in PCI-Treated Patients: A Rocky Road Toward More Individualized Treatment. Sibbing, D. J Am Coll Cardiol 83, 1382-1385 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38599714
AKAP12 Overexpression Affects Cardiac Function via PDE8. Subramanian, H. & Nikolaev, V. O. Circ Res 134, 1023-1025 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38603476
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment. von Haehling, S., Assmus, B., Bekfani, T., Dworatzek, E., Edelmann, F., Hashemi, D., Hellenkamp, K., Kempf, T., Raake, P., Schutt, K. A., Wachter, R., Schulze, P. C., Hasenfuss, G., Bohm, M. & Bauersachs, J. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38602566
Left atrial strain predicts the rhythm outcome in patients with persistent atrial fibrillation undergoing left atrial cryoablation during minimally invasive mitral valve repair. Yildirim, Y., Yildirim, S., Petersen, J., Alassar, Y., Sarwari, H., Sinning, C., Blankenberg, S., Reichenspurner, H. & Pecha, S. Front Cardiovasc Med11, 1373310 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38601047
Role of kinin receptors in skin pigmentation. Ferreira, J. C. P., Soley, B. S., Pawloski, P. L., Moreira, C. G., Pesquero, J. B., Bader, M., Calixto, J. B., Cabrini, D. A. & Otuki, M. F. Eur J Pharmacol 973, 176537 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38604546
Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation - Insights from Castle HTX. Moersdorf, M., Tijssen, J. G. P., Marrouche, N. F., Crijns, H., Costard-Jaeckle, A., Bergau, L., Hindricks, G., Dagres, N., Sossalla, S., Schramm, R., Fox, H., Fink, T., El Hamriti, M., Sciacca, V., Konietschke, F., Rudolph, V., Gummert, J., Sommer, P., Sohns, C. & Investigators, C. H. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/38604590
Comment on: 'Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart' by Saint-Martin Willer et al. Prüser, M., Wiedmann, F. & Schmidt, C. J Physiol 602, 2141-2142 (2024).
Transition from asymptomatic to symptomatic systolic chronic heart failure: rationale and design of TransitionCHF. Sandek, A., Edelmann, F., Gertler, C., Friede, T., Wachter, R., Hasenfuss, G. & Transition, C. H. F. c. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38606543
Characterization of Biomarkers of Thrombo-Inflammation in Patients with First-Diagnosed Atrial Fibrillation. Friebel, J., Wegner, M., Blobaum, L., Schencke, P. A., Jakobs, K., Puccini, M., Ghanbari, E., Lammel, S., Thevathasan, T., Moos, V., Witkowski, M., Landmesser, U. & Rauch-Krohnert, U. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38612918
Improvement in Visceral Adipose Tissue and LDL Cholesterol by High PUFA Intake: 1-Year Results of the NutriAct Trial. Meyer, N. M. T., Pohrt, A., Wernicke, C., Pletsch-Borba, L., Apostolopoulou, K., Haberbosch, L., Machann, J., Pfeiffer, A. F. H., Spranger, J. & Mai, K. Nutrients 16 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38613089
Optimization of Enzymatic and Chemical Decellularization of Native Porcine Heart Valves for the Generation of Decellularized Xenografts. Saeid Nia, M., Floder, L. M., Seiler, J. A., Puehler, T., Pommert, N. S., Berndt, R., Meier, D., Sellers, S. L., Sathananthan, J., Zhang, X., Hasler, M., Gorb, S. N., Warnecke, G. & Lutter, G. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38612836
Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study. Fabritz, L., Chua, W., Cardoso, V. R., Al-Taie, C., Borof, K., Suling, A., Krause, L., Kany, S., Magnussen, C., Wegscheider, K., Breithardt, G., Crijns, H., Camm, A. J., Gkoutos, G., Ellinor, P. T., Goette, A., Schotten, U., Wienhues-Thelen, U. H., Zeller, T., Schnabel, R. B., Zapf, A. & Kirchhof, P. Cardiovasc Res 120, 855-868 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38613511
Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium. Raisi-Estabragh, Z., Szabo, L., McCracken, C., Bulow, R., Aquaro, G. D., Andre, F., Le, T. T., Sucha, D., Condurache, D. G., Salih, A. M., Chadalavada, S., Aung, N., Lee, A. M., Harvey, N. C., Leiner, T., Chin, C. W. L., Friedrich, M. G., Barison, A., Dorr, M. & Petersen, S. E. JACC Cardiovasc Imaging 17, 746-762 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38613554
Thinner is better: Intentional weight loss and cardiovascular risk. Abraham, J., Butler, J. & Anker, S. D. Med 5, 275-277 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38614070
In Vitro Comparison of a Closed and Semi-closed Leaflet Design for Adult and Pediatric Transcatheter Heart Valves. Breitenstein-Attach, A., Steitz, M., Sun, X., Hao, Y., Kiekenap, J., Emeis, J., Tuladhar, S. R., Berger, F. & Schmitt, B. Ann Biomed Eng 52, 2051-2064 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38615078
Health economic evaluation of blended collaborative care for older multimorbid heart failure patients: study protocol. Derendorf, L., Stock, S., Simic, D., Shukri, A., Zelenak, C., Nagel, J., Friede, T., Herbeck Belnap, B., Herrmann-Lingen, C., Pedersen, S. S., Sorensen, J., Muller & On Behalf Of The Escape Consortium, D. Cost Eff Resour Alloc 22, 29 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38615050
Ca2+/calmodulin-dependent kinase IIdeltaC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak. Dewenter, M., Seitz, T., Steinbrecher, J. H., Westenbrink, B. D., Ling, H., Lehnart, S. E., Wehrens, X. H. T., Backs, J., Brown, J. H., Maier, L. S. & Neef, S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38616546
Mortality and rehospitalization in patients with pre-existing implantable pacemakers undergoing catheter ablation are related to increased comorbidity burden-data from the German Ablation Registry. Frommeyer, G., Reinke, F., Brachmann, J., Lewalter, T., Tilz, R. R., Willems, S., Straube, F., Akin, I., Lugenbiel, P., Hochadel, M., Senges, J. & Eckardt, L. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38619577
Nanopore Detection of METTL3-Dependent m6A-Modified mRNA Reveals a New Mechanism Regulating Cardiomyocyte Mitochondrial Metabolism. Rabolli, C. P., Naarmann-de Vries, I. S., Makarewich, C. A., Baskin, K. K., Dieterich, C. & Accornero, F. Circulation149, 1319-1322 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38620081
APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation. Lorenzo, J. P., Molla, L., Amro, E. M., Ibarra, I. L., Ruf, S., Neber, C., Gkougkousis, C., Ridani, J., Subramani, P. G., Boulais, J., Harjanto, D., Vonica, A., Di Noia, J. M., Dieterich, C., Zaugg, J. B. & Papavasiliou, F. N. Proc Natl Acad Sci U S A 121, e2312330121 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38625936
Prospects for Leveraging the Microbiota as Medicine for Hypertension. Durgan, D. J., Zubcevic, J., Vijay-Kumar, M., Yang, T., Manandhar, I., Aryal, S., Muralitharan, R. R., Li, H. B., Li, Y., Abais-Battad, J. M., Pluznick, J. L., Muller, D. N., Marques, F. Z. & Joe, B. Hypertension 81, 951-963 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630799
Trajectories of functional and structural myocardial parameters in post-COVID-19 syndrome-insights from mid-term follow-up by cardiovascular magnetic resonance. Groschel, J., Grassow, L., van Dijck, P., Bhoyroo, Y., Blaszczyk, E. & Schulz-Menger, J. Front Cardiovasc Med 11, 1357349 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38628318
Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce Lung Cancer Regrowth after Crizotinib Treatment. Horvat, N. K., Chocarro, S., Marques, O., Bauer, T. A., Qiu, R., Diaz-Jimenez, A., Helm, B., Chen, Y., Sawall, S., Sparla, R., Su, L., Klingmuller, U., Barz, M., Hentze, M. W., Sotillo, R. & Muckenthaler, M. U. ACS Nano 18, 11025-11041 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38626916
Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial. Patel, R. B., Silvestry, F. E., Komtebedde, J., Solomon, S. D., Hasenfuss, G., Litwin, S. E., Borlaug, B. A., Price, M. J., Kawash, R., Hummel, S. L., Cutlip, D. E., Leon, M. B., van Veldhuisen, D. J., Rieth, A. J., McKenzie, S., Bugger, H., Mazurek, J. A., Kapadia, S. R., Vanderheyden, M., Ky, B. & Shah, S. J. JAMA Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630494
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human. Roh, J. D., Castro, C., Yu, A., Rana, S., Shahul, S., Gray, K. J., Honigberg, M. C., Ricke-Hoch, M., Iwamoto, Y., Yeri, A., Kitchen, R., Guerra, J. B., Hobson, R., Chaudhari, V., Chang, B., Sarma, A., Lerchenmuller, C., Al Sayed, Z. R., Diaz Verdugo, C., Xia, P., Skarbianskis, N., Zeisel, A., Bauersachs, J., Kirkland, J. L., Karumanchi, S. A., Gorcsan, J., 3rd, Sugahara, M., Damp, J., Hanley-Yanez, K., Ellinor, P. T., Arany, Z., McNamara, D. M., Investigators, I., Hilfiker-Kleiner, D. & Rosenzweig, A. Sci Transl Med 16, eadi0077 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630848
Clinical practice of continuous rhythm monitoring after embolic stroke of undetermined source. von Falkenhausen, A. S., Wischmann, J., Keidel, L. M., Kellnar, A. M., Thaler, R., Lackermair, K., Estner, H. L., Hoglinger, G., Massberg, S., Kaab, S., Kellert, L. & Sinner, M. F. PLoS One 19, e0302404 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630693
Prediction of cardiac worsening through to cardiogenic shock in patients with acute heart failure. Beer, B. N., Kellner, C., Sundermeyer, J., Besch, L., Dettling, A., Kirchhof, P., Blankenberg, S., Magnussen, C. & Schrage, B. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38632837
Expanding the Chemical Space of Transforming Growth Factor-beta (TGFbeta) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives. Langle, D., Wojtowicz-Piotrowski, S., Priegann, T., Keller, N., Wesseler, F., Reckzeh, E. S., Steffens, K., Grathwol, C., Lemke, J., Flasshoff, M., Nather, C., Jonson, A. C., Link, A., Koch, O., Di Guglielmo, G. M. & Schade, D. ACS Pharmacol Transl Sci 7, 1069-1085 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38633593
Development of a Trusted Third Party at a Large University Hospital: Design and Implementation Study. Wundisch, E., Hufnagl, P., Brunecker, P., Meier Zu Ummeln, S., Trager, S., Kopp, M., Prasser, F. & Weber, J. JMIR Med Inform 12, e53075 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38632712
A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function. Ameri, P., Mercurio, V., Pollesello, P., Anker, M. S., Backs, J., Bayes-Genis, A., Borlaug, B. A., Burkhoff, D., Caravita, S., Chan, S. Y., de Man, F., Giannakoulas, G., Gonzalez, A., Guazzi, M., Hassoun, P. M., Hemnes, A. R., Maack, C., Madden, B., Melenovsky, V., Muller, O. J., Papp, Z., Pullamsetti, S. S., Rainer, P. P., Redfield, M. M., Rich, S., Schiattarella, G. G., Skaara, H., Stellos, K., Tedford, R. J., Thum, T., Vachiery, J. L., van der Meer, P., Van Linthout, S., Pruszczyk, P., Seferovic, P., Coats, A. J. S., Metra, M., Rosano, G., Rosenkranz, S. & Tocchetti, C. G. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38639017
Biomarker Periodic Repolarization Dynamics Indicates Enhanced Risk for Arrhythmias and Sudden Cardiac Death in Myocardial Infarction in Pigs. Bauer, J., Vlcek, J., Pauly, V., Hesse, N., Xia, R., Mo, L., Chivukula, A. S., Villgrater, H., Dressler, M., Hildebrand, B., Wolf, E., Rizas, K. D., Bauer, A., Kaab, S., Tomsits, P., Schuttler, D. & Clauss, S. J Am Heart Assoc, e032405 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38639363
Detecting m(6)A at single-molecular resolution via direct RNA sequencing and realistic training data. Chan, A., Naarmann-de Vries, I. S., Scheitl, C. P. M., Hobartner, C. & Dieterich, C. Nat Commun 15, 3323 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637518
Comprehensive characterization of cardiac contraction for improved post-infarction risk assessment. Corral Acero, J., Lamata, P., Eitel, I., Zacur, E., Evertz, R., Lange, T., Backhaus, S. J., Stiermaier, T., Thiele, H., Bueno-Orovio, A., Schuster, A. & Grau, V. Sci Rep 14, 8951 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637609
Associations between 47 anthropometric markers derived from a body scanner and relative fat-free mass in a population-based study. Dietzmann, M., Radke, D., Markus, M. R., Wiese, M., Volzke, H., Felix, S. B., Dorr, M., Bahls, M. & Ittermann, T. BMC Public Health 24, 1079 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637778
Late-stage meta-C-H alkylation of pharmaceuticals to modulate biological properties and expedite molecular optimisation in a single step. Guillemard, L., Ackermann, L. & Johansson, M. J. Nat Commun 15, 3349 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637496
Cardiometabolic and immune response to exercise training in patients with metabolic syndrome: retrospective analysis of two randomized clinical trials. Lechner, K., Kia, S., von Korn, P., Dinges, S. M., Mueller, S., Tjonna, A. E., Wisloff, U., Van Craenenbroeck, E. M., Pieske, B., Adams, V., Pressler, A., Landmesser, U., Halle, M. & Krankel, N. Front Cardiovasc Med 11, 1329633 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38638882
Microtubules: highway to ... arrhythmia? Liutkute, A., Prosser, B. L. & Voigt, N. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637305
Impact of endothelial shear stress on coronary atherosclerotic plaque progression and composition: A meta-analysis and systematic review. Candreva, A., Buongiorno, A. L., Matter, M. A., Rizzini, M. L., Giacobbe, F., Ravetti, E., Giannino, G., Carmagnola, L., Gilhofer, T., Gallo, D., Chiastra, C., Stahli, B. E., Iannaccone, M., Morbiducci, U., Porto, I., De Ferrari, G. M. & D'Ascenzo, F. Int J Cardiol 407, 132061 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641263
Letter to the editor: fasting decreases expression of microRNAs linked to endothelial pathophysiology in mononuclear cells of healthy subjects. Honeycutt, D., Schmidt-Trucksass, A., Brink, M., Krankel, N. & Kropfl, J. M. Apoptosis 29, 935-937 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38642320
Tolerance induction through early feeding to prevent food allergy in infants and children with sensitization against food allergens (TIFFANI): rationale, study design, and methods of a randomized controlled trial. Kalb, B., Meixner, L., Heller, S., Dolle-Bierke, S., Roll, S., Tissen-Diabate, T., Lau, S., Forslund, S., Marenholz, I., Lee, Y. A., Thiel, A., Babina, M., Scheffel, J., Worm, M. & Beyer, K. Trials 25, 272 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641837
E-learning-an interventional element of the PRiVENT project to improve weaning expertise. Michels-Zetsche, J. D., Schubert-Haack, J., Tanck, K., Neetz, B., Iberl, G., Muller, M., Kempa, A., Joves, B., Rheinhold, A., Ghiani, A., Tsitouras, K., Schneider, A., Rauch, C., Gehrig, P., Biehler, E., Fleischauer, T., Britsch, S., Frerk, T., Szecsenyi, J., Herth, F. J. F., Trudzinski, F. C. & Group, P. R.-S. BMC Med Educ24, 420 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641835
S100A1: a promising therapeutic target for heart failure. Noll, D., Kehr, D., Most, P. & Ritterhoff, J. Expert Opin Ther Targets, 1-4 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641766
Biomarkers of NRF2 signalling: Current status and future challenges. Morgenstern, C., Lastres-Becker, I., Demirdogen, B. C., Costa, V. M., Daiber, A., Foresti, R., Motterlini, R., Kalyoncu, S., Arioz, B. I., Genc, S., Jakubowska, M., Trougakos, I. P., Piechota-Polanczyk, A., Mickael, M., Santos, M., Kensler, T. W., Cuadrado, A. & Copple, I. M. Redox Biol 72, 103134 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38643749
Venous Vascular Closure System Versus Figure-of-Eight Suture Following Atrial Fibrillation Ablation - The STYLE-AF Study. Tilz, R., Feher, M., Vogler, J., Bode, K., Duta, A., Ortolan, A., Lopez, L. D., Kuchler, M., Mamaev, R., Lyan, E., Sommer, P., Braun, M., Sciacca, V., Demming, T., Maslova, V., Kuck, K. H., Heeger, C. H., Eitel, C. & Popescu, S. S. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38647070
Pathological high intraocular pressure induces glial cell reactive proliferation contributing to neuroinflammation of the blood-retinal barrier via the NOX2/ET-1 axis-controlled ERK1/2 pathway. Shi, X., Li, P., Herb, M., Liu, H., Wang, M., Wang, X., Feng, Y., van Beers, T., Xia, N., Li, H. & Prokosch, V. J Neuroinflammation 21, 105 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38649885
A parametric study on pulse duplicator design and valve hemodynamics. Smid, C. C., Pappas, G. A., Falk, V., Ermanni, P. & Cesarovic, N. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/38651352
Validation of the Klinrisk chronic kidney disease progression model in the FIDELITY population. Tangri, N., Ferguson, T., Leon, S. J., Anker, S. D., Filippatos, G., Pitt, B., Rossing, P., Ruilope, L. M., Farjat, A. E., Farag, Y. M. K., Schloemer, P., Lawatscheck, R., Rohwedder, K. & Bakris, G. L. Clin Kidney J 17, sfae052 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38650758
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathy. Wali, R., Xu, H., Cheruiyot, C., Saleem, H. N., Janshoff, A., Habeck, M. & Ebert, A. Biol Chem (2024). https://www.ncbi.nlm.nih.gov/pubmed/38651266
Randomized investigation of the MitraClip device in heart failure: Design and rationale of the RESHAPE-HF2 trial design. Anker, S. D., Friede, T., von Bardeleben, R. S., Butler, J., Fatima, K., Diek, M., Heinrich, J., Hasenfuss, G., Schillinger, W. & Ponikowski, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38654139
SRRM2 splicing factor modulates cell fate in early development. Carvalho, S., Zea-Redondo, L., Tang, T. C. C., Stachel-Braum, P., Miller, D., Caldas, P., Kukalev, A., Diecke, S., Grosswendt, S., Grosso, A. R. & Pombo, A. Biol Open 13 (2024). www.ncbi.nlm.nih.gov/pubmed/38656788
Karyopherin alpha2 is a maternal effect gene required for early embryonic development and female fertility in mice. Rother, F., Depping, R., Popova, E., Huegel, S., Heiler, A., Hartmann, E. & Bader, M. FASEB J 38, e23623 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38656660
Impacts of gene variants on drug effects-the foundation of genotype-guided pharmacologic therapy for long QT syndrome and short QT syndrome. Zhao, Z., Zang, X., Niu, K., Song, W., Wang, X., Mugge, A., Aweimer, A., Hamdani, N., Zhou, X., Zhao, Y., Akin, I. & El-Battrawy, I. EBioMedicine 103, 105108 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38653189
Economic Considerations of Cardiovascular Implantable Electronic Devices for The Treatment of Heart Failure. Elsner, C., Bettin, S., Tilz, R. & Häckl, D. Curr Heart Fail Rep 21, 186-193 (2024). https://pubmed.ncbi.nlm.nih.gov/38662154/
Pacing Using Cardiac Implantable Electric Device During TAVR: 10-Year Experience of a High-Volume Center. Haum, M., Steffen, J., Sadoni, S., Theiss, H., Stark, K., Estner, H., Massberg, S., Deseive, S. & Lackermair, K. JACC Cardiovasc Interv 17, 1020-1028 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38658116
Permanent Pacemaker Implantation and Long-Term Outcomes of Patients Undergoing Concomitant Mitral and Tricuspid Valve Surgery. Iribarne, A., Alabbadi, S. H., Moskowitz, A. J., Ailawadi, G., Badhwar, V., Gillinov, M., Thourani, V. H., Allen, K. B., Halkos, M. E., Patel, N. C., Kramer, R. S., D'Alessandro, D., Raymond, S., Chang, H. L., Gupta, L., Fenton, K. N., Taddei-Peters, W. C., Chu, M. W. A., Falk, V., Chikwe, J., Jeffries, N., Bagiella, E., O'Gara, P. T., Gelijns, A. C. & Egorova, N. N. J Am Coll Cardiol 83, 1656-1668 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38658105
Transportation Noise Pollution and Cardiovascular Health. Munzel, T., Molitor, M., Kuntic, M., Hahad, O., Roosli, M., Engelmann, N., Basner, M., Daiber, A. & Sorensen, M. Circ Res 134, 1113-1135 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38662856
Repurposing of an antiasthmatic drug may reduce NETosis and myocardial ischaemia/reperfusion injury. Amponsah-Offeh, M., Tual-Chalot, S. & Stellos, K. Eur Heart J 45, 1681-1683 (2024). https://pubmed.ncbi.nlm.nih.gov/38666350/
Targeting immune cell recruitment in atherosclerosis. Döring, Y., van der Vorst, E. P. C. & Weber, C. Nat Rev Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38664575/
Body surface scan anthropometrics are associated with grip strength in the general population. Filges, B., Bahls, M., Radke, D., Gross, S., Ewert, R., Stubbe, B., Markus, M. R., Felix, S. B., Volzke, H., Dorr, M., Kohler, A. & Ittermann, T. Nutr Metab Cardiovasc Dis 34, 1864-1873 (2024). www.ncbi.nlm.nih.gov/pubmed/38664126
Categorization of Patients With Pulmonary Embolism by Charlson Comorbidity Index. Keller, K., Schmitt, V. H., Hahad, O., Espinola-Klein, C., Munzel, T., Lurz, P., Konstantinides, S. & Hobohm, L. Am J Med 137, 727-735 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38663792
Predictors of atrial fibrillation after embolic stroke of undetermined source in patients with implantable loop recorders. Kreimer, F., Aweimer, A., El-Battrawy, I., Labedi, A., Schneider, R., Haghikia, A., Mügge, A. & Gotzmann, M. Neurol Sci (2024). https://pubmed.ncbi.nlm.nih.gov/38664303/
Obesity-related inflammatory protein signature in cardiovascular clinical outcomes: results from the Gutenberg Health Study. Panova-Noeva, M., Koeck, T., Schoelch, C., Schulz, A., Prochaska, J. H., Michal, M., Strauch, K., Schuster, A. K., Lackner, K. J., Münzel, T., Hennige, A. M. & Wild, P. S. Obesity (Silver Spring) (2024). https://pubmed.ncbi.nlm.nih.gov/38664310/
Impact of Quantitative ST-T Analysis in Patients With Suspected Myocardial Infarction Presenting With Right Bundle Branch Block. Sorensen, N. A., Fakhri, Y., Gossling, A., Neumann, J. T., Haller, P. M., Toprak, B., Senftinger, J., Lehmacher, J., Scharlemann, L., Schock, A., Twerenbold, R., Westermann, D., Bille Andersson, H., Jensen, L. O., Holmvang, L. & Clemmensen, P. Am J Med 137, 770-775 e771 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38670517
Validation of a simple clinical tool for screening of acute lacunar stroke-A substudy of the WAKE-UP trial. Arba, F., Rinaldi, C., Jensen, M., Endres, M., Fiebach, J. B., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Thijs, V., Gerloff, C., Wardlaw, J. M. & Thomalla, G. Int J Stroke, 17474930241253987 (2024). https://pubmed.ncbi.nlm.nih.gov/38676549/
Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: data from a practice-based longitudinal cohort. Hobohm, L., Paschke, L. M., Farmakis, I. T., Barco, S., Partovi, S., Münzel, T., Konstantinides, S., Keller, K. & Below, M. J Thromb Haemost (2024). https://pubmed.ncbi.nlm.nih.gov/38677594/
Transcatheter Heart Valve Explantation for TAVR Failure (TAVR-Explant): A Heart Valve Collaboratory Expert Consensus Document on Operative Techniques. Kaneko, T., Bapat, V. N., Alakhtar, A. M., Zaid, S., George, I., Grubb, K. J., Harrington, K., Pirelli, L., Atkins, M., Desai, N. D., Bleiziffer, S., Noack, T., Modine, T., Denti, P., Kempfert, J., Ruge, H., Vitanova, K., Falk, V., Thourani, V. H., Bavaria, J. E., Reardon, M. J., Mack, M. J., Borger, M. A., Leon, M. B., Tang, G. H. L. & Fukuhara, S. J Thorac Cardiovasc Surg (2024). https://pubmed.ncbi.nlm.nih.gov/38677492/
Technological advancements in functional interpretation of genome-wide association studies (GWAS) findings: bridging the gap to clinical translation. Aherrahrou, R. & Kaikkonen, M. U. FEBS Lett (2024). https://pubmed.ncbi.nlm.nih.gov/38683017/
Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors. Amado Costa, L., Oliveira Amaral, L. B., Mourão, F. A. G., Bader, M., Santos, R. A. S., Campagnole-Santos, M. J. & Kangussu, L. M. Horm Behav 163, 105551 (2024). https://pubmed.ncbi.nlm.nih.gov/38678724/
Competence and contributions of radiologists to cardiac CT and MR imaging across Europe. Dewey, M. Eur Radiol (2024). https://pubmed.ncbi.nlm.nih.gov/38683386/
Comparative electroencephalography analysis: Marathon runners during tapering versus sedentary controls reveals no significant differences. Moussiopoulou, J., Handrack-Bonnet, M., Pross, B., Pogarell, O., Keeser, D., Halle, M., Falkai, P., Scherr, J., Hasan, A. & Roeh, A. Brain Behav 14, e3480 (2024). https://pubmed.ncbi.nlm.nih.gov/38680019/
Multidisciplinary care of peripartum heart failure: A scientific statement of the Heart Failure Association of the ESC. Rakisheva, A., Sliwa, K., Bauersachs, J., Van Linthout, S., Chopra, V. K., Bayes-Genis, A., Fruzzetti, F., Cannatà, A., Deniau, B., Mebazaa, A., Savarese, G., Ray, R., Vitale, C., Metra, M. & Rosano, G. M. C. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38679896/
Be prepared for the unexpected: Mind-stretching in ST-elevation myocardial infarction with situs inversus totalis. Viggiani, G., Ibrahim, T., Allescher, J. & Steger, A. Clin Case Rep 12, e8768 (2024). https://pubmed.ncbi.nlm.nih.gov/38681040/
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish. Cardeira-da-Silva, J., Wang, Q., Sagvekar, P., Mintcheva, J., Latting, S., Günther, S., Ramadass, R., Yekelchyk, M., Preussner, J., Looso, M., Junker, J. P. & Stainier, D. Y. R. Nat Commun 15, 3637 (2024). https://pubmed.ncbi.nlm.nih.gov/38684665/
A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy. Figueroa, K. P., Gross, C., Buena-Atienza, E., Paul, S., Gandelman, M., Kakar, N., Sturm, M., Casadei, N., Admard, J., Park, J., Zuhlke, C., Hellenbroich, Y., Pozojevic, J., Balachandran, S., Handler, K., Zittel, S., Timmann, D., Erdlenbruch, F., Herrmann, L., Feindt, T., Zenker, M., Klopstock, T., Dufke, C., Scoles, D. R., Koeppen, A., Spielmann, M., Riess, O., Ossowski, S., Haack, T. B. & Pulst, S. M. Nat Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/38684900
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function. Khani, S., Topel, H., Kardinal, R., Tavanez, A. R., Josephrajan, A., Larsen, B. D. M., Gaudry, M. J., Leyendecker, P., Egedal, N. M., Güller, A. S., Stanic, N., Ruppert, P. M. M., Gaziano, I., Hansmeier, N. R., Schmidt, E., Klemm, P., Vagliano, L. M., Stahl, R., Duthie, F., Krause, J. H., Bici, A., Engelhard, C. A., Gohlke, S., Frommolt, P., Gnad, T., Rada-Iglesias, A., Pradas-Juni, M., Schulz, T. J., Wunderlich, F. T., Pfeifer, A., Bartelt, A., Jastroch, M., Wachten, D. & Kornfeld, J. W. Nat Metab (2024). https://pubmed.ncbi.nlm.nih.gov/38684889/
Embolic strokes of undetermined source: a clinical consensus statement of the ESC Council on Stroke, the European Association of Cardiovascular Imaging and the European Heart Rhythm Association of the ESC. Ntaios, G., Baumgartner, H., Doehner, W., Donal, E., Edvardsen, T., Healey, J. S., Iung, B., Kamel, H., Kasner, S. E., Korompoki, E., Navi, B. B., Pristipino, C., Saba, L., Schnabel, R. B., Svennberg, E. & Lip, G. Y. H. Eur Heart J (2024). https://pubmed.ncbi.nlm.nih.gov/38685132/
März
Paper of the Month
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9
DZHK authors: Felix A. Trogisch, Aya Abouissa, Merve Keles, Gesine M. Dittrich, Julio Cordero, Steve Grein, Shruthi Hemanna, Luka Nicin, Sofia-Iris Bibli, Stefanie Dimmeler, Gergana Dobreva, Joerg Heineke. Science Translational Medicine.
[Heart and blood: clonal hematopoiesis]. Dimmeler, S. & Zeiher, A. Herz 49, 105-110 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38424288
Alterations of iron homeostasis as a potential druggable driver of long COVID. Marques, O. & Muckenthaler, M. U. Nat Immunol 25, 387-389 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38429459
Rest and exercise-stress estimated pulmonary capillary wedge pressure using real-time free-breathing cardiovascular magnetic resonance imaging. Backhaus, S. J., Schulz, A., Lange, T., Evertz, R., Kowallick, J. T., Hasenfuss, G. & Schuster, A. J Cardiovasc Magn Reson 26, 101032 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38431079
Role of human Kallistatin in glucose and energy homeostasis in mice. Sandforth, L., Brachs, S., Reinke, J., Willmes, D., Sancar, G., Seigner, J., Juarez-Lopez, D., Sandforth, A., McBride, J. D., Ma, J. X., Haufe, S., Jordan, J. & Birkenfeld, A. L. Mol Metab 82, 101905 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38431218
Applying Machine Learning to Blood Count Data Predicts Sepsis with ICU Admission. Steinbach, D., Ahrens, P. C., Schmidt, M., Federbusch, M., Heuft, L., Lubbert, C., Nauck, M., Grundling, M., Isermann, B., Gibb, S. & Kaiser, T. Clin Chem 70, 506-515 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38431275
Trends of mortality rate in patients with congenital heart defects in Germany-analysis of nationwide data of the Federal Statistical Office of Germany. Abdul-Khaliq, H., Gomes, D., Meyer, S., von Kries, R., Wagenpfeil, S., Pfeifer, J. & Poryo, M. Clin Res Cardiol 113, 750-760 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38436738
Non-femoral focused transaxillary access in TAVI: GARY data analysis and future trends. Meertens, M. M., Adam, M., Beckmann, A., Ensminger, S., Frerker, C., Seiffert, M., Sinning, J. M., Bekeredjian, R., Walther, T., Beyersdorf, F., Mollmann, H., Balaban, U., Eghbalzadeh, K., Rudolph, T. K. & Bleiziffer, S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38436739
Shortening in-hospital stay after transcatheter aortic valve implantation: a deja vu in percutaneous interventions. Mehilli, J. Eur Heart J 45, 963-965 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38437639
Impairment of the adrenergic reserve associated with exercise intolerance in a murine model of heart failure with preserved ejection fraction. Semmler, L., Jeising, T., Huettemeister, J., Bathe-Peters, M., Georgoula, K., Roshanbin, R., Sander, P., Fu, S., Bode, D., Hohendanner, F., Pieske, B., Annibale, P., Schiattarella, G. G., Oeing, C. U. & Heinzel, F. R. Acta Physiol (Oxf)240, e14124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38436094
Coronary Artery Calcium Score Predicts Major Adverse Cardiovascular Events in Stable Chest Pain. Biavati, F., Saba, L., Boussoussou, M., Kofoed, K. F., Benedek, T., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Stechovsky, C., Sakalyte, G., Cemerlic Adic, N., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M., Ilnicka-Suckiel, M., Plank, F., Knuuti, J., Faria, R., Schroder, S., Berry, C., Ruzsics, B., Rieckmann, N., Kubiak, C., Hansen, K. S., Muller-Nordhorn, J., Maurovich-Horvat, P., Sigvardsen, P. E., Benedek, I., Orr, C., Valente, F. X., Zvaigzne, L., Suchanek, V., Jankauskas, A., Adic, F., Woinke, M., Cadogan, D., Lecumberri, I., Thwaite, E., Kruk, M., Neskovic, A. N., Mancone, M., Kusmierz, D., Feuchtner, G., Pietila, M., Ribeiro, V. G., Drosch, T., Delles, C., Cau, R., Fisher, M., Merkely, B., Kragelund, C., Aurelian, R., Kelly, S., Garcia Del Blanco, B., Rubio, A., Szilveszter, B., Hove, J. D., Rodean, I., Regan, S., Cuellar Calabria, H., Edes, I. F., Larsen, L., Hodas, R., Napp, A. E., Haase, R., Feger, S., Mohamed, M., Serna-Higuita, L. M., Neumann, K., Dreger, H., Rief, M., Wieske, V., Budoff, M. J., Estrella, M., Martus, P., Bosserdt, M., Dewey, M. & Group, D. T. Radiology 310, e231557 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38441097
Organisation of paediatric echocardiography laboratories and governance of echocardiography services and training in Europe: current status, disparities, and potential solutions. A survey from the Association for European Paediatric and Congenital Cardiology (AEPC) imaging working group. Cantinotti, M., Voges, I., Miller, O., Raimondi, F., Grotenhuis, H., Bharucha, T., Garrido, A. O., Valsangiacomo, E., Roest, A., Sunnegardh, J., Salaets, T., Brun, H., Khraiche, D., Jossif, A., Schokking, M., Sebate-Rotes, A., Meyer-Szary, J., Deri, A., Koopman, L., Herberg, U., du Marchie Sarvaas, G., Leskinen, M., Tchana, B., Ten Harkel, A. D. J., Odemis, E., Morrison, L., Steimetz, M., Laser, K. T., Doros, G., Bellshan-Revell, H., Muntean, I., Anagostopoulou, A., Alpman, M. S., Hunter, L., Ojala, T., Bhat, M., Olejnik, P., Wacker, J., Bonello, B., Ramcharan, T., Greil, G., Marek, J., DiSalvo, G. & McMahon, C. J. Cardiol Young, 1-9 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38439642
Empagliflozin and risk of lower respiratory tract infection in heart failure with mildly reduced and preserved ejection fraction: An EMPEROR-Preserved analysis. Ferreira, J. P., Zannad, F., Packer, M., Filippatos, G., Pocock, S. J., Vasques-Novoa, F., Bohm, M., Butler, J. & Anker, S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38439585
Long-term function of a novel autologous transcatheter pulmonary heart valve implant in an adult animal model. Kiekenap, J., Sun, X., Hao, Y., Steitz, M., Breitenstein-Attach, A., Emeis, J., Berger, F. & Schmitt, B. Catheter Cardiovasc Interv 103, 597-606 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38440908
Atlas of cardiac endothelial cell enhancer elements linking the mineralocorticoid receptor to pathological gene expression. Deng, L., Pollmeier, L., Bednarz, R., Cao, C., Laurette, P., Wirth, L., Mamazhakypov, A., Bode, C., Hein, L., Gilsbach, R. & Lother, A. Sci Adv 10, eadj5101 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38446896
Bi-Gaussian analysis reveals distinct education-related alterations in spherical equivalent and axial length-results from the Gutenberg Health Study. Hartmann, A., Grabitz, S. D., Wagner, F. M., Wild, P. S., Muller-Nurasyid, M., Lackner, K. J., Beutel, M. E., Munzel, T., Tuscher, O., Schattenberg, J. M., Pfeiffer, N. & Schuster, A. K. Graefes Arch Clin Exp Ophthalmol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38446204
Metabolic cost of unloading pedalling in different groups of patients with pulmonary hypertension and volunteers. Ittermann, T., Kaczmarek, S., Obst, A., Konemann, R., Bahls, M., Dorr, M., Stubbe, B., Heine, A., Habedank, D. & Ewert, R. Sci Rep 14, 5394 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38443426
Aortic arch blood flow measurements as a predictor of successful ECMO weaning in cardiogenic shock. Kellnar, A., Naumann, D., Scherer, C., Lusebrink, E., Joskowiak, D., Peterss, S., Hagl, C., Massberg, S., Orban, M. & Stremmel, C. Heliyon 10, e26773 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38444470
Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort. Maushagen, J., Addin, N. S., Schuppert, C., Ward-Caviness, C. K., Nattenmuller, J., Adamski, J., Peters, A., Bamberg, F., Schlett, C. L., Wang-Sattler, R. & Rospleszcz, S. Biomark Res 12, 31 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38444025
Publisher Correction: A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Ferrell, M., Wang, Z., Anderson, J. T., Li, X. S., Witkowski, M., DiDonato, J. A., Hilser, J. R., Hartiala, J. A., Haghikia, A., Cajka, T., Fiehn, O., Sangwan, N., Demuth, I., Konig, M., Steinhagen-Thiessen, E., Landmesser, U., Tang, W. H. W., Allayee, H. & Hazen, S. L. Nat Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38448791
Reproducibility assessment of rapid strains in cardiac MRI: Insights and recommendations for clinical application. Halfmann, M. C., Hopman, L., Korperich, H., Blaszczyk, E., Groschel, J., Schulz-Menger, J., Salatzki, J., Andre, F., Friedrich, S. & Emrich, T. Eur J Radiol 174, 111386 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38447431
Recurrence of Atrial Fibrillation in Patients With New-Onset Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting. Herrmann, F. E. M., Taha, A., Nielsen, S. J., Martinsson, A., Hansson, E. C., Juchem, G. & Jeppsson, A. JAMA Netw Open 7, e241537 (2024). www.ncbi.nlm.nih.gov/pubmed/38451520
In preprints: Shh signaling activity predicts cardiac laterality in Astyanax mexicanus populations. Juan, T. & Ebnicher, G. Development 151 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38451186
Genome-wide characterization of circulating metabolic biomarkers. Karjalainen, M. K., Karthikeyan, S., Oliver-Williams, C., Sliz, E., Allara, E., Fung, W. T., Surendran, P., Zhang, W., Jousilahti, P., Kristiansson, K., Salomaa, V., Goodwin, M., Hughes, D. A., Boehnke, M., Fernandes Silva, L., Yin, X., Mahajan, A., Neville, M. J., van Zuydam, N. R., de Mutsert, R., Li-Gao, R., Mook-Kanamori, D. O., Demirkan, A., Liu, J., Noordam, R., Trompet, S., Chen, Z., Kartsonaki, C., Li, L., Lin, K., Hagenbeek, F. A., Hottenga, J. J., Pool, R., Ikram, M. A., van Meurs, J., Haller, T., Milaneschi, Y., Kahonen, M., Mishra, P. P., Joshi, P. K., Macdonald-Dunlop, E., Mangino, M., Zierer, J., Acar, I. E., Hoyng, C. B., Lechanteur, Y. T. E., Franke, L., Kurilshikov, A., Zhernakova, A., Beekman, M., van den Akker, E. B., Kolcic, I., Polasek, O., Rudan, I., Gieger, C., Waldenberger, M., Asselbergs, F. W., China Kadoorie Biobank Collaborative, G., Estonian Biobank Research, T., FinnGen, Hayward, C., Fu, J., den Hollander, A. I., Menni, C., Spector, T. D., Wilson, J. F., Lehtimaki, T., Raitakari, O. T., Penninx, B., Esko, T., Walters, R. G., Jukema, J. W., Sattar, N., Ghanbari, M., Willems van Dijk, K., Karpe, F., McCarthy, M. I., Laakso, M., Jarvelin, M. R., Timpson, N. J., Perola, M., Kooner, J. S., Chambers, J. C., van Duijn, C., Slagboom, P. E., Boomsma, D. I., Danesh, J., Ala-Korpela, M., Butterworth, A. S. & Kettunen, J. Nature 628, 130-138 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38448586
Bionic Nanocoating of Prosthetic Grafts Significantly Reduces Bacterial Growth. Pecha, S., Reuter, L., Ohdah, S., Petersen, J., Pahrmann, C., Aytar Celik, P., Cabuk, A., Reichenspurner, H. & Yildirim, Y. ACS Appl Mater Interfaces 16, 13534-13542 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38447594
Estimating potential cardiovascular health benefits of improved population level control of LDL cholesterol through a twice-yearly siRNA-based approach: A simulation study of a health-system level intervention. Ray, K. K., Gunn, L. H., Conde, L. G., Raal, F. J., Wright, R. S., Gosselin, N. H., Leiter, L. A., Koenig, W., Schwartz, G. G., Landmesser, U. & investigators, O. Atherosclerosis 391, 117472 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38447434
Noise annoyance and cardiovascular disease risk: results from a 10-year follow-up study. Hahad, O., Gilan, D., Michal, M., Tuscher, O., Chalabi, J., Schuster, A. K., Keller, K., Hobohm, L., Schmitt, V. H., Konig, J., Lackner, K. J., Wild, P., Schattenberg, J. M., Daiber, A. & Munzel, T. Sci Rep 14, 5619 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38454061
Biophysical Investigation of RNA ⋅ DNA : DNA Triple Helix and RNA : DNA Heteroduplex Formation by the lncRNAs MEG3 and Fendrr. Krause, N. M., Bains, J. K., Blechar, J., Richter, C., Bessi, I., Grote, P., Leisegang, M. S., Brandes, R. P. & Schwalbe, H. Chembiochem 25, e202400049 (2024). https://pubmed.ncbi.nlm.nih.gov/38456652/
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition. Ducommun, S., Jannig, P. R., Cervenka, I., Murgia, M., Mittenbuhler, M. J., Chernogubova, E., Dias, J. M., Jude, B., Correia, J. C., Van Vranken, J. G., Ocana-Santero, G., Porsmyr-Palmertz, M., McCann Haworth, S., Martinez-Redondo, V., Liu, Z., Carlstrom, M., Mann, M., Lanner, J. T., Teixeira, A. I., Maegdefessel, L., Spiegelman, B. M. & Ruas, J. L. Mol Metab 82, 101912 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38458566
Impact of depersonalization on the course of depression: longitudinal observations from the gutenberg health study. Michal, M., Wiltink, J., Tibubos, A. N., Wild, P. S., Munzel, T., Lackner, K., Pfeiffer, N., Konig, J., Gieswinkel, A., Beutel, M. & Kerahrodi, J. G. BMC Psychiatry 24, 196 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38459472
One small STEP, one giant leap: Semaglutide in the obese phenotype of heart failure with preserved ejection fraction. Sato, R. & von Haehling, S. Med 5, 181-183 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38460497
Association analysis between an epigenetic alcohol risk score and blood pressure. Bui, H., Keshawarz, A., Wang, M., Lee, M., Ratliff, S. M., Lin, L., Birditt, K. S., Faul, J. D., Peters, A., Gieger, C., Delerue, T., Kardia, S. L. R., Zhao, W., Guo, X., Yao, J., Rotter, J. I., Liu, D., Tavares, J. F., Pehlivan, G., Breteler, M. M. B., Karabegovic, I., Ochoa-Rosales, C., Voortman, T., Ghanbari, M., van Meurs, J. B. J., Nasr, M. K., Dorr, M., Grabe, H. J., London, S. J., Teumer, A., Waldenberger, M., Weir, D. R., Smith, J. A., Levy, D., Ma, J. & Liu, C. medRxiv (2024). https://www.ncbi.nlm.nih.gov/pubmed/38464320
Prescribing Patterns and Outcomes of Edoxaban in Atrial Fibrillation Patients From Asia - One-Year Data From the Global ETNA-AF Program. Choi, J. I., Kiatchoosakun, S., Jiampo, P., Tse, H. F., Soo, Y. O. Y., Wang, C. C., Lee, C. H., Pecen, L., Unverdorben, M., De Caterina, R. & Kirchhof, P. Circ Rep 6, 86-93 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38464984
Sex-specific structural and functional cardiac remodeling during healthy aging assessed by cardiovascular magnetic resonance. Grassow, L., Groschel, J., Saad, H., Kruger, L. D., Kuhnt, J., Muller, M., Hadler, T., Blaszczyk, E. & Schulz-Menger, J. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38466347
Incidence of microvascular dysfunction is increased in hyperlipidemic mice, reducing cerebral blood flow and impairing remote memory. Hernandez Torres, L. D., Rezende, F., Peschke, E., Will, O., Hovener, J. B., Spiecker, F., Ozorhan, U., Lampe, J., Stolting, I., Aherrahrou, Z., Kunne, C., Kusche-Vihrog, K., Matschl, U., Hille, S., Brandes, R. P., Schwaninger, M., Muller, O. J. & Raasch, W. Front Endocrinol (Lausanne) 15, 1338458 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38469142
Prognostic and diagnostic implications of impaired rest and exercise-stress left atrial compliance in heart failure with preserved ejection fraction: Insights from the HFpEF stress trial. Backhaus, S. J., Schulz, A., Lange, T., Schmidt-Schweda, L. S., Hellenkamp, K., Evertz, R., Kowallick, J. T., Kutty, S., Hasenfuss, G. & Schuster, A. Int J Cardiol 404, 131949 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38471649
Protein Kinase D Plays a Crucial Role in Maintaining Cardiac Homeostasis by Regulating Post-Translational Modifications of Myofilament Proteins. Herwig, M., Begovic, M., Budde, H., Delalat, S., Zhazykbayeva, S., Sieme, M., Schneider, L., Jaquet, K., Mugge, A., Akin, I., El-Battrawy, I., Fielitz, J. & Hamdani, N. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38474037
The Current Evidence of Pulmonary Embolism Response Teams and Their Role in Future. Hobohm, L., Farmakis, I. T., Duerschmied, D. & Keller, K. Hamostaseologie (2024). https://www.ncbi.nlm.nih.gov/pubmed/38471662
Optimal sample size allocation for two-arm superiority and non-inferiority trials with binary endpoints. Kirchner, M., Schupke, S. & Kieser, M. Pharm Stat (2024). https://www.ncbi.nlm.nih.gov/pubmed/38471740
Influence of a 7-day Transalpine Trail Run on cardiac biomarkers and myocardial function. Esefeld, K., Geisberger, M., Dinges, S. M., Hambrecht, J., Stegmuller, F., Rasper, M., Nadjiri, J., Roeschenthaler, F., Holdenrieder, S., Scharhag, J. & Halle, M. Scand J Med Sci Sports 34, e14590 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38483076
Characterization of anthracycline-induced cardiotoxicity by diffusion tensor magnetic resonance imaging. Lohr, D., Thiele, A., Stahnke, M., Braun, V. M., Klopfleisch, R., Klein, O., Dresen, S., Landmesser, U., Foryst-Ludwig, A., Kintscher, U., Schreiber, L. M. & Beyhoff, N. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38483601
Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer's disease. Martinelli, F., Heinken, A., Henning, A. K., Ulmer, M. A., Hensen, T., Gonzalez, A., Arnold, M., Asthana, S., Budde, K., Engelman, C. D., Estaki, M., Grabe, H. J., Heston, M. B., Johnson, S., Kastenmuller, G., Martino, C., McDonald, D., Rey, F. E., Kilimann, I., Peters, O., Wang, X., Spruth, E. J., Schneider, A., Fliessbach, K., Wiltfang, J., Hansen, N., Glanz, W., Buerger, K., Janowitz, D., Laske, C., Munk, M. H., Spottke, A., Roy, N., Nauck, M., Teipel, S., Knight, R., Kaddurah-Daouk, R. F., Bendlin, B. B., Hertel, J. & Thiele, I. Sci Rep 14, 6095 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38480804
Ex vivo evaluation of 3 different right ventricular outflow tract substitutes. Saisho, H., Geisler, I., Scharfschwerdt, M., Sadat, N., Zhang, X., Puehler, T., Ensminger, S., Fujita, B. & Aboud, A. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38479833
Impact of epicardial adipose tissue on cardiac function and morphology in patients with diastolic dysfunction. Schulz, A., Backhaus, S. J., Lange, T., Evertz, R., Kutty, S., Kowallick, J. T., Hasenfuss, G. & Schuster, A. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38480481
Circadian assessment of heart failure using explainable deep learning and novel multi-parameter polar images. Alkhodari, M., Khandoker, A. H., Jelinek, H. F., Karlas, A., Soulaidopoulos, S., Arsenos, P., Doundoulakis, I., Gatzoulis, K. A., Tsioufis, K. & Hadjileontiadis, L. J. Comput Methods Programs Biomed 248, 108107 (2024). www.ncbi.nlm.nih.gov/pubmed/38484409
A supervised, externally validated machine learning model for artifact and drainage detection in high-resolution intracranial pressure monitoring data. Huo, S., Nelde, A., Meisel, C., Scheibe, F., Meisel, A., Endres, M., Vajkoczy, P., Wolf, S., Willms, J. F., Boss, J. M. & Keller, E. J Neurosurg 141, 509-517 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38489814
Correction: Definition, Classification, Diagnosis and Differential Diagnosis of Diabetes Mellitus: Update 2023. Pleus, S., Tytko, A., Landgraf, R., Heinemann, L., Werner, C., Muller-Wieland, D., Ziegler, A. G., Muller, U. A., Freckmann, G., Kleinwechter, H., Schleicher, E., Nauck, M. & Petersmann, A. Exp Clin Endocrinol Diabetes 132, e1 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38484786
Temporary extracorporeal life support: single-center experience with a new concept. Nersesian, G., Lewin, D., Ott, S., Schoenrath, F., Hrytsyna, Y., Starck, C., Spillmann, F., O'Brien, B., Falk, V., Potapov, E. & Lanmueller, P. Interdiscip Cardiovasc Thorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38490254
Post-hoc standardisation of parametric T1 maps in cardiovascular magnetic resonance imaging: a proof-of-concept. Viezzer, D., Hadler, T., Groschel, J., Ammann, C., Blaszczyk, E., Kolbitsch, C., Hufnagel, S., Kranzusch-Gross, R., Lange, S. & Schulz-Menger, J. EBioMedicine 102, 105055 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38490103
Scrutinizing mechanical circulatory support in cardiogenic shock: Have we jumped the gun? Lusebrink, E., Lanz, H. & Thiele, H. Crit Care 28, 80 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38491468
Characterizing the immune response to myocardial infarction in pigs. Schnitter, F., Stangl, F., Noeske, E., Bille, M., Stadtmuller, A., Vogt, N., Sicklinger, F., Leuschner, F., Frey, A., Schreiber, L., Frantz, S., Beyersdorf, N., Ramos, G., Gladow, N. & Hofmann, U. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38491291
Editorial: Cardiovascular inflammaging: basic and translational aspects. Barcena, M. L., Aslam, M. & Ladilov, Y. Front Cardiovasc Med 11, 1385683 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38495941
A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. Nagarajan, P., Winkler, T. W., Bentley, A. R., Miller, C. L., Kraja, A. T., Schwander, K., Lee, S., Wang, W., Brown, M. R., Morrison, J. L., Giri, A., O'Connell, J. R., Bartz, T. M., de Las Fuentes, L., Gudmundsdottir, V., Guo, X., Harris, S. E., Huang, Z., Kals, M., Kho, M., Lefevre, C., Luan, J., Lyytikainen, L. P., Mangino, M., Milaneschi, Y., Palmer, N. D., Rao, V., Rauramaa, R., Shen, B., Stadler, S., Sun, Q., Tang, J., Theriault, S., van der Graaf, A., van der Most, P. J., Wang, Y., Weiss, S., Westerman, K. E., Yang, Q., Yasuharu, T., Zhao, W., Zhu, W., Altschul, D., Ansari, M. A. Y., Anugu, P., Argoty-Pantoja, A. D., Arzt, M., Aschard, H., Attia, J. R., Bazzanno, L., Breyer, M. A., Brody, J. A., Cade, B. E., Chen, H. H., Ida Chen, Y. D., Chen, Z., de Vries, P. S., Dimitrov, L. M., Do, A., Du, J., Dupont, C. T., Edwards, T. L., Evans, M. K., Faquih, T., Felix, S. B., Fisher-Hoch, S. P., Floyd, J. S., Graff, M., Gu, C., Gu, D., Hairston, K. G., Hanley, A. J., Heid, I. M., Heikkinen, S., Highland, H. M., Hood, M. M., Kahonen, M., Karvonen-Gutierrez, C. A., Kawaguchi, T., Kazuya, S., Kelly, T. N., Komulainen, P., Levy, D., Lin, H. J., Liu, P. Y., Marques-Vidal, P., McCormick, J. B., Mei, H., Meigs, J. B., Menni, C., Nam, K., Nolte, I. M., Pacheco, N. L., Petty, L. E., Polikowsky, H. G., Province, M. A., Psaty, B. M., Raffield, L. M., Raitakari, O. T., Rich, S. S., Riha, R. L., Risch, L., Risch, M., Ruiz-Narvaez, E. A., Scott, R. J., Sitlani, C. M., Smith, J. A., Sofer, T., Teder-Laving, M., Volker, U., Vollenweider, P., Wang, G., van Dijk, K. W., Wilson, O. D., Xia, R., Yao, J., Young, K. L., Zhang, R., Zhu, X., Below, J. E., Boger, C. A., Conen, D., Cox, S. R., Dorr, M., Feitosa, M. F., Fox, E. R., Franceschini, N., Gharib, S. A., Gudnason, V., Harlow, S. D., He, J., Holliday, E. G., Kutalik, Z., Lakka, T. A., Lawlor, D. A., Lee, S., Lehtimaki, T., Li, C., Liu, C. T., Magi, R., Matsuda, F., Morrison, A. C., Penninx, B. W., Peyser, P. A., Rotter, J. I., Snieder, H., Spector, T. D., Wagenknecht, L. E., Wareham, N. J., Zonderman, A. B., North, K. E., Fornage, M., Million Veteran, P., Hung, A. M., Manning, A. K., Gauderman, J., Chen, H., Munroe, P. B., Rao, D. C., van Heemst, D., Redline, S., Noordam, R. & Wang, H. medRxiv (2024). https://www.ncbi.nlm.nih.gov/pubmed/38496537
Biomarkers for predicting atrial fibrillation: An explorative sub-analysis of the randomised SCREEN-AF trial. Schmalstieg-Bahr, K., Gladstone, D. J., Hummers, E., Suerbaum, J., Healey, J. S., Zapf, A., Koster, D., Werhahn, S. M. & Wachter, R. Eur J Gen Pract30, 2327367 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38497412
Heart failure with Sarcopenia: A Bibliometric review from 1995 to 2022. You, Y., Meng, T., Lu, X., Zhu, X., Lv, M., Shou, X., He, Q. & Hu, Y. Heliyon 10, e27913 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38496860
CMR reference values of right ventricular volumetric variables in patients with hypoplastic left heart syndrome. Ballenberger, A., Caliebe, A., Krupickova, S., Uebing, A., Gabbert, D. D. & Voges, I. J Cardiovasc Magn Reson, 101038 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38499270
Generation of marmoset primordial germ cell-like cells under chemically defined conditions. Kurlovich, J., Rodriguez Polo, I., Dovgusha, O., Tereshchenko, Y., Cruz, C. R. V., Behr, R. & Gunesdogan, U. Life Sci Alliance 7 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38499329
Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials. Sun, M. L., Yao, W., Wang, X. Y., Gao, S., Varady, K. A., Forslund, S. K., Zhang, M., Shi, Z. Y., Cao, F., Zou, B. J., Sun, M. H., Liu, K. X., Bao, Q., Xu, J., Qin, X., Xiao, Q., Wu, L., Zhao, Y. H., Zhang, D. Y., Wu, Q. J. & Gong, T. T. EClinicalMedicine 70, 102519 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38500840
Takotsubo syndrome outcomes predicted by thyroid hormone signature: insights from cluster analysis of a multicentre registry. Aweimer, A., Dietrich, J. W., Santoro, F., Fabregas, M. C., Mugge, A., Nunez-Gil, I. J., Vazirani, R., Vedia, O., Patz, T., Ragnatela, I., Arcari, L., Volpe, M., Corbi-Pascual, M., Martinez-Selles, M., Almendro-Delia, M., Sionis, A., Uribarri, A., Thiele, H., Brunetti, N. D., Eitel, I., Stiermaier, T., Hamdani, N., Abumayyaleh, M., Akin, I. & El-Battrawy, I. EBioMedicine 102, 105063 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38502972
Comparative preclinical assessment of drug-coated balloons: a blessing and a curse for clinical translation. Joner, M. & Wild, L. EuroIntervention 20, e338-e340 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38506738
Comparison of two self-expanding transcatheter heart valves for degenerated surgical bioprostheses: the AVENGER multicentre registry. Kim, W. K., Seiffert, M., Ruck, A., Leistner, D. M., Dreger, H., Wienemann, H., Adam, M., Mollmann, H., Blumenstein, J., Eckel, C., Buono, A., Maffeo, D., Messina, A., Holzamer, A., Sossalla, S., Costa, G., Barbanti, M., Motta, S., Tamburino, C., von der Heide, I., Glasmacher, J., Sherif, M., Seppelt, P., Fischtlscherer, S., Walther, T., Castriota, F., Nerla, R., Frerker, C., Schmidt, T., Wolf, A., Adamaszek, M. M., Giannini, F., Vanhaverbeke, M., Van de Walle, S., Stammen, F., Toggweiler, S., Brunner, S., Mangieri, A., Gitto, M., Kaleschke, G., Ninios, V., Ninios, I., Hubner, J., Xhepa, E., Renker, M., Charitos, E. I., Joner, M. & Rheude, T. EuroIntervention 20, e363-e375 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38506737
The role of computed tomography prior to transcatheter aortic valve implantation: preprocedural planning and simultaneous coronary artery assessment. Renker, M. & Korosoglou, G. J Thorac Dis 16, 833-838 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38505069
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation. Vos, W. G., van Os, B. W., den Toom, M., Beckers, L., van Roomen, C., van Tiel, C. M., Mohapatra, B. C., Band, H., Nitz, K., Weber, C., Atzler, D., de Winther, M. P. J., Bosmans, L. A., Lutgens, E. & Seijkens, T. T. P. Front Immunol 15, 1297893 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38504977
Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets. Xu, X., Khunsriraksakul, C., Eales, J. M., Rubin, S., Scannali, D., Saluja, S., Talavera, D., Markus, H., Wang, L., Drzal, M., Maan, A., Lay, A. C., Prestes, P. R., Regan, J., Diwadkar, A. R., Denniff, M., Rempega, G., Ryszawy, J., Krol, R., Dormer, J. P., Szulinska, M., Walczak, M., Antczak, A., Matias-Garcia, P. R., Waldenberger, M., Woolf, A. S., Keavney, B., Zukowska-Szczechowska, E., Wystrychowski, W., Zywiec, J., Bogdanski, P., Danser, A. H. J., Samani, N. J., Guzik, T. J., Morris, A. P., Liu, D. J., Charchar, F. J., Human Kidney Tissue Resource Study, G. & Tomaszewski, M. Nat Commun 15, 2359 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38504097
Finerenone cardiovascular and kidney outcomes by age and sex: FIDELITY post hoc analysis of two phase 3, multicentre, double-blind trials. Bansal, S., Canziani, M. E. F., Birne, R., Anker, S. D., Bakris, G. L., Filippatos, G., Rossing, P., Ruilope, L. M., Farjat, A. E., Kolkhof, P., Lage, A., Brinker, M. & Pitt, B. BMJ Open 14, e076444 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38508632
Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner. ElBeck, Z., Hossain, M. B., Siga, H., Oskolkov, N., Karlsson, F., Lindgren, J., Walentinsson, A., Koppenhofer, D., Jarvis, R., Burli, R., Jamier, T., Franssen, E., Firth, M., Degasperi, A., Bendtsen, C., Menzies, R. I., Streckfuss-Bomeke, K., Kohlhaas, M., Nickel, A. G., Lund, L. H., Maack, C., Vegvari, A. & Betsholtz, C. Nat Commun 15, 2358 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38509128
Contemporary catheter ablation of complex atrial tachycardias after prior atrial fibrillation ablation: pulsed field versus radiofrequency current energy ablation guided by high-density mapping. Gunawardene, M. A., Harloff, T., Jularic, M., Dickow, J., Wahedi, R., Anwar, O., Wohlmuth, P., Gessler, N., Hartmann, J. & Willems, S. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38513110
Smart hospital: achieving interoperability and raw data collection from medical devices in clinical routine. Martens, E., Haase, H. U., Mastella, G., Henkel, A., Spinner, C., Hahn, F., Zou, C., Fava Sanches, A., Allescher, J., Heid, D., Strauss, E., Maier, M. M., Lachmann, M., Schmidt, G., Westphal, D., Haufe, T., Federle, D., Rueckert, D., Boeker, M., Becker, M., Laugwitz, K. L., Steger, A. & Muller, A. Front Digit Health 6, 1341475 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38510279
A latent clinical-anatomical dimension relating metabolic syndrome to brain structure and cognition. Petersen, M., Hoffstaedter, F., Nagele, F. L., Mayer, C., Schell, M., Rimmele, D. L., Zyriax, B. C., Zeller, T., Kuhn, S., Gallinat, J., Fiehler, J., Twerenbold, R., Omidvarnia, A., Patil, K. R., Eickhoff, S. B., Thomalla, G. & Cheng, B. Elife 12 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38512127
An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells. Ruan, D., Xuan, Y., Tam, T., Li, Z., Wang, X., Xu, S., Herrmann, D., Niemann, H., Lai, L., Gao, X., Nowak-Imialek, M. & Liu, P. Nat Protoc (2024). https://www.ncbi.nlm.nih.gov/pubmed/38509352
Secondary stroke prevention in people with atrial fibrillation: treatments and trials. Seiffge, D. J., Cancelloni, V., Raber, L., Paciaroni, M., Metzner, A., Kirchhof, P., Fischer, U., Werring, D. J., Shoamanesh, A. & Caso, V. Lancet Neurol 23, 404-417 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38508836
The homeobox transcription factor DUXBL controls exit from totipotency. Vega-Sendino, M., Luttmann, F. F., Olbrich, T., Chen, Y., Kuenne, C., Stein, P., Tillo, D., Carey, G. I., Zhong, J., Savy, V., Radonova, L., Lu, T., Saykali, B., Kim, K. P., Domingo, C. N., Schuler, L., Gunther, S., Bentsen, M., Bosnakovski, D., Scholer, H., Kyba, M., Maity, T. K., Jenkins, L. M., Looso, M., Williams, C. J., Kim, J. & Ruiz, S. Nat Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/38509386
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment. Kaiser, R., Gold, C., Joppich, M., Loew, Q., Akhalkatsi, A., Mueller, T. T., Offensperger, F., Droste Zu Senden, A., Popp, O., di Fina, L., Knottenberg, V., Martinez-Navarro, A., Eivers, L., Anjum, A., Escaig, R., Bruns, N., Briem, E., Dewender, R., Muraly, A., Akgol, S., Ferraro, B., Hoeflinger, J. K. L., Polewka, V., Khaled, N. B., Allgeier, J., Tiedt, S., Dichgans, M., Engelmann, B., Enard, W., Mertins, P., Hubner, N., Weckbach, L., Zimmer, R., Massberg, S., Stark, K., Nicolai, L. & Pekayvaz, K. Sci Adv 10, eadl1710 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38517968
Knock-out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para- and transcellular solute transport. Pfeffer, T., Krug, S. M., Kracke, T., Schurfeld, R., Colbatzky, F., Kirschner, P., Medert, R., Freichel, M., Schumacher, D., Bartosova, M., Zarogiannis, S. G., Muckenthaler, M. U., Altamura, S., Pezer, S., Volk, N., Schwab, C., Duensing, S., Fleming, T., Heidenreich, E., Zschocke, J., Hell, R., Poschet, G., Schmitt, C. P. & Peters, V. Acta Physiol (Oxf) 240, e14126 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38517248
Genetic ablation of Lmp2 increases the susceptibility for impaired cardiac function. Trogisch, F. A., Koser, F., Michel, S., Liem, D. A., Florea, B. I., Hecker, M. & Drews, O. Front Mol Biosci 11, 1148948 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38516190
FAPI-PET in Cardiovascular Disease. Higuchi, T., Serfling, S. E., Leistner, D. M., Speer, T. & Werner, R. A. Semin Nucl Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38519308
The Conceptual Definition of Sarcopenia: Delphi Consensus from the Global Leadership Initiative in Sarcopenia (GLIS). Kirk, B., Cawthon, P. M., Arai, H., Avila-Funes, J. A., Barazzoni, R., Bhasin, S., Binder, E. F., Bruyere, O., Cederholm, T., Chen, L. K., Cooper, C., Duque, G., Fielding, R. A., Guralnik, J., Kiel, D. P., Landi, F., Reginster, J. Y., Sayer, A. A., Visser, M., von Haehling, S., Woo, J., Cruz-Jentoft, A. J. & Global Leadership Initiative in Sarcopenia, g. Age Ageing 53 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38520141
Interpretability of bi-level variable selection methods. Buch, G., Schulz, A., Schmidtmann, I., Strauch, K. & Wild, P. S. Biom J 66, e2300063 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38519877
Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis. Hansen, C. E., Kamermans, A., Mol, K., Berve, K., Rodriguez-Mogeda, C., Fung, W. K., van Het Hof, B., Fontijn, R. D., van der Pol, S. M. A., Michalick, L., Kuebler, W. M., Kenkhuis, B., van Roon-Mom, W., Liedtke, W., Engelhardt, B., Kooij, G., Witte, M. E. & de Vries, H. E. J Neuroinflammation 21, 72 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521959
Quantification of ventricular stress in univentricular hearts during early childhood using age-independent zlog-NT-proBNP. Palm, J., Ono, M., Niedermaier, C., Horer, J., Hoffmann, G., Holdenrieder, S., Klawonn, F. & Ewert, P. Int J Cardiol 406, 131983 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521506
Author s Reply to Anterior Mitral Line and Pulsed Filed Ablation: different energy source, similar results? Reissmann, B., Wenzel, J. P., Lemoine, M. D., Rottner, L., My, I., Moser, F., Obergassel, J., Nies, M., Riess, J., Ismaili, D., Nikorowitsch, J., Kirchhof, P., Rillig, A., Metzner, A. & Ouyang, F. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521383
Reply to the Editor- Anterior mitral line and pulsed field ablation: Different energy source, similar results? Reissmann, B., Wenzel, J. P., Lemoine, M. D., Rottner, L., My, I., Moser, F., Obergassel, J., Nies, M., Riess, J., Ismaili, D., Nikorowitsch, J., Kirchhof, P., Rillig, A., Metzner, A. & Ouyang, F. Heart Rhythm 21, 1255-1256 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521383
A mini-review: phosphodiesterases in charge to balance intracellular cAMP during T-cell activation. Bielenberg, M., Kurelic, R., Frantz, S. & Nikolaev, V. O. Front Immunol15, 1365484 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38524120
Scrutinizing the Role of Venoarterial Extracorporeal Membrane Oxygenation: Has Clinical Practice Outpaced the Evidence? Lusebrink, E., Binzenhofer, L., Hering, D., Villegas Sierra, L., Schrage, B., Scherer, C., Speidl, W. S., Uribarri, A., Sabate, M., Noc, M., Sandoval, E., Erglis, A., Pappalardo, F., De Roeck, F., Tavazzi, G., Riera, J., Roncon-Albuquerque, R., Jr., Meder, B., Luedike, P., Rassaf, T., Hausleiter, J., Hagl, C., Zimmer, S., Westermann, D., Combes, A., Zeymer, U., Massberg, S., Schafer, A., Orban, M. & Thiele, H. Circulation 149, 1033-1052 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38527130
Mitophagy modulation for the treatment of cardiovascular diseases. Forte, M., D'Ambrosio, L., Schiattarella, G. G., Salerno, N., Perrone, M. A., Loffredo, F. S., Bertero, E., Pilichou, K., Manno, G., Valenti, V., Spadafora, L., Bernardi, M., Simeone, B., Sarto, G., Frati, G., Perrino, C., Sciarretta, S., Italian Society of Cardiology Working Group on, C. & Molecular Biology of the, H. Eur J Clin Invest 54, e14199 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38530070
Proteomic profiles of left atrial volume and its influence on response to spironolactone: Findings from the HOMAGE trial and STANISLAS cohort. Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H. P., Delles, C., Clark, A. L., Edelmann, F., Gonzalez, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A. J., Rossignol, P., Cleland, J. G. F., Zannad, F., Girerd, N., on behalf of the, H. T. C. & Investigators. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38528728
Effects of occlusal wear on 16-year progression of non-carious cervical lesions-Results of the study of health in Pomerania (SHIP-START). Giller, M., Holtfreter, B., Ruge, S., Volzke, H. & Bernhardt, O. J Oral Rehabil 51, 1184-1192 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38532285
Chimney Stenting vs BASILICA for Prevention of Acute Coronary Obstruction During Transcatheter Aortic Valve Replacement. Mangieri, A., Richter, I., Gitto, M., Abdelhafez, A., Bedogni, F., Lanz, J., Montorfano, M., Unbehaun, A., Giannini, F., Nerla, R., Taramasso, M., Ielasi, A., Rudolph, T., Ferlini, M., Ribichini, F., Poletti, E., Latib, A., Colombo, A., Van Mieghem, N. M., Thiele, H. & Abdel-Wahab, M. JACC Cardiovasc Interv 17, 742-752 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38538170
Clusters of longitudinal risk profile trajectories are associated with cardiometabolic diseases: Results from the population-based KORA cohort. Niedermayer, F., Schauberger, G., Rathmann, W., Klug, S. J., Thorand, B., Peters, A. & Rospleszcz, S. PLoS One 19, e0300966 (2024). www.ncbi.nlm.nih.gov/pubmed/38547172
Reverse cardio-oncology: is heart failure-mediated gut dysbiosis the mechanistic driver of colorectal cancer progression? Rangrez, A. Y. & Frey, N. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38547372
Non-invasive measurements of blood glucose levels by time-gating mid-infrared optoacoustic signals. Uluc, N., Glasl, S., Gasparin, F., Yuan, T., He, H., Justel, D., Pleitez, M. A. & Ntziachristos, V. Nat Metab (2024). https://www.ncbi.nlm.nih.gov/pubmed/38538980
Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease. Li, L., Pang, S., Starnecker, F., Mueller-Myhsok, B. & Schunkert, H. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38551411
A streamlined pathway for transcatheter aortic valve implantation: the BENCHMARK study. Frank, D., Durand, E., Lauck, S., Muir, D. F., Spence, M., Vasa-Nicotera, M., Wood, D., Saia, F., Urbano-Carrillo, C. A., Bouchayer, D., Iliescu, V. A., Etienne, C. S., Leclercq, F., Auffret, V., Asmarats, L., Di Mario, C., Veugeois, A., Maly, J., Schober, A., Nombela-Franco, L., Werner, N., Gomez-Hospital, J. A., Mascherbauer, J., Musumeci, G., Meneveau, N., Meurice, T., Mahfoud, F., De Marco, F., Seidler, T., Leuschner, F., Joly, P., Collet, J. P., Vogt, F., Di Lorenzo, E., Kuhn, E., Disdier, V. P., Hachaturyan, V., Luske, C. M., Rakova, R., Wesselink, W., Kurucova, J., Bramlage, P., McCalmont, G. & Group, B. I. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38554125
Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies. Strohm, L., Daiber, A., Ubbens, H., Krishnankutty, R., Oelze, M., Kuntic, M., Hahad, O., Klein, V., Hoefer, I. E., von Kriegsheim, A., Kleinert, H., Atzler, D., Lurz, P., Weber, C., Wild, P. S., Munzel, T., Knosalla, C., Lutgens, E. & Daub, S. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38554187
First-in-human gene editing for lipid lowering: the initial results. Tual-Chalot, S. & Stellos, K. Cardiovasc Res 120, e5-e8 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38554379
Sex-specific trends in incidence of first myocardial infarction among people with and without diabetes between 1985 and 2016 in a German region. Claessen, H., Narres, M., Heier, M., Kvitkina, T., Linkohr, B., Wolff, G., Roden, M., Icks, A. & Peters, A. Cardiovasc Diabetol 23, 110 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38555466
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung. Dorner, P. J., Anandakumar, H., Rowekamp, I., Fiocca Vernengo, F., Millet Pascual-Leone, B., Krzanowski, M., Sellmaier, J., Bruning, U., Fritsche-Guenther, R., Pfannkuch, L., Kurth, F., Milek, M., Igbokwe, V., Lober, U., Gutbier, B., Holstein, M., Heinz, G. A., Mashreghi, M. F., Schulte, L. N., Klatt, A. B., Caesar, S., Wienhold, S. M., Offermanns, S., Mack, M., Witzenrath, M., Jordan, S., Beule, D., Kirwan, J. A., Forslund, S. K., Wilck, N., Bartolomaeus, H., Heimesaat, M. M. & Opitz, B. Nat Commun15, 2788 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38555356
February
Paper of the Month
Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure
DZHK authors: Alessio Alogna, Uwe Primeßnig, Felix Hohendanner, Carsten Tschöpe, Burkert M. Pieske, Frank R. Heinzel. Journal of the American College of Cardiology 2024.
Genome engineering of a neuronal specific, optogenetic, induced pluripotent stem cell line. Aline Schmoll, K., Mager, T., Tse, T. P., Alameldeen, A., Zimmermann, W. H. & Zafeiriou, M. P. Stem Cell Res 75, 103317 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38295750
Transcatheter aortic valve replacement in heart failure. Parikh, P. B., Mack, M., Stone, G. W., Anker, S. D., Gilchrist, I. C., Kalogeropoulos, A. P., Packer, M., Skopicki, H. A. & Butler, J. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38297972
The Association of Off-Hour vs. On-Hour ICU Admission Time with Mortality in Patients with Cardiogenic Shock - a Retrospective Multicenter Analysis. Naumann, D., Fischer, J., Gmeiner, J., Lusebrink, E., Beer, B. N., Grieger, M., Giousouf, A., Schrage, B., Stremmel, C., Massberg, S., Orban, M. & Scherer, C. Eur Heart J Acute Cardiovasc Care (2024). https://www.ncbi.nlm.nih.gov/pubmed/38306600
The German version of the mHealth App Usability Questionnaire (GER-MAUQ): Translation and validation study in patients with cardiovascular disease. Tacke, T., Nohl-Deryk, P., Lingwal, N., Reimer, L. M., Starnecker, F., Guthlin, C., Gerlach, F. M., Schunkert, H., Jonas, S. & Muller, A. Digit Health 10, 20552076231225168 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38303970
Current and past depression as risk factors for incident type 2 diabetes mellitus and pre-diabetes in men and women: evidence from a longitudinal community cohort. Wicke, F. S., Otten, D., Schulz, A., Wild, P. S., Lackner, K. J., Munzel, T., Konig, J., Ernst, M., Wiltink, J., Reiner, I., Ghaemi Kerahrodi, J., Pfeiffer, N. & Beutel, M. E. Diabetol Metab Syndr 16, 34 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38303090
Adiposity influences on myocardial deformation: a cardiovascular magnetic resonance feature tracking study in people with overweight to obesity without established cardiovascular disease. Bolz, C., Blaszczyk, E., Mayr, T., Lim, C., Haufe, S., Jordan, J., Barckow, P., Groschel, J. & Schulz-Menger, J. Int J Cardiovasc Imaging 40, 643-654 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38308113
Stroke Related Brain-Heart Crosstalk: Pathophysiology, Clinical Implications, and Underlying Mechanisms. Fan, X., Cao, J., Li, M., Zhang, D., El-Battrawy, I., Chen, G., Zhou, X., Yang, G. & Akin, I. Adv Sci (Weinh), e2307698 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38308187
TransCatheter aortic valve implantation and fractional flow reserve-guided percutaneous coronary intervention versus conventional surgical aortic valve replacement and coronary bypass grafting for treatment of patients with aortic valve stenosis and multivessel or advanced coronary disease: The transcatheter valve and vessels trial (TCW trial): Design and rationale. Kedhi, E., Rroku, A., Hermanides, R. S., Dambrink, J. H., Singh, S., Berg, J. T., van Ginkel, D. J., Hudec, M., Amoroso, G., Amat-Santos, I. J., Andreas, M., Teles, R. C., Bonnet, G., Van Belle, E., Conradi, L., van Garsse, L., Wojakowski, W., Voudris, V., Sacha, J., Cervinka, P., Lipsic, E., Somi, S., Nombela-Franco, L., Postma, S., Piayda, K., De Luca, G., Malinofski, K. & Modine, T. Am Heart J 270, 86-94 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38309610
Association of plasma proteomics with incident coronary heart disease in individuals with and without type 2 diabetes: results from the population-based KORA study. Luo, H., Huemer, M. T., Petrera, A., Hauck, S. M., Rathmann, W., Herder, C., Koenig, W., Hoyer, A., Peters, A. & Thorand, B. Cardiovasc Diabetol 23, 53 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38310303
Body plethysmography - additional information on exercise capacity in patients with congenital heart disease? Hock, J., Bessar, M., Ewert, P. & Hager, A. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38315211
Delayed (68)Ga-FAPI-46 PET/MR imaging confirms ongoing fibroblast activation in patients after acute myocardial infarction. Kupusovic, J., Kessler, L., Kazek, S., Chodyla, M. K., Umutlu, L., Zarrad, F., Nader, M., Fendler, W. P., Varasteh, Z., Hermann, K., Dobrev, D., Wakili, R., Rassaf, T., Siebermair, J. & Rischpler, C. Int J Cardiol Heart Vasc 50, 101340 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38313450
Role of multidrug-resistant bacteria in weaning from invasive mechanical ventilation. Michels-Zetsche, J. D., Gassmann, V., Jasuja, J. K., Neetz, B., Hoger, P., Meis, J., Britsch, S., Sommerwerck, U., Fahndrich, S., Bornitz, F., Muller, M. M., Herth, F. J. F. & Trudzinski, F. C. Respir Res 25, 69 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38317197
Mineralocorticoid receptor antagonists for the prevention of atrial fibrillation in patients with and without heart failure: one more beneficial effect? Zurkan, D., Pitt, B. & Edelmann, F. Eur Heart J 45, 775-777 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38319069
Epicardial adipose tissue as an independent predictor of long-term outcome in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. Schulz, A., Beuthner, B. E., Bottiger, Z. M., Gersch, S. S., Lange, T., Gronwald, J., Evertz, R., Backhaus, S. J., Kowallick, J. T., Hasenfuss, G. & Schuster, A. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38324040
Secreted Protein Profiling of Human Aortic Smooth Muscle Cells Identifies Vascular Disease Associations. Aherrahrou, R., Baig, F., Theofilatos, K., Lue, D., Beele, A., Ord, T., Kaikkonen, M. U., Aherrahrou, Z., Cheng, Q., Ghosh, S. K. B., Karnewar, S., Karnewar, V., Finn, A. V., Owens, G. K., Joner, M., Mayr, M. & Civelek, M. Arterioscler Thromb Vasc Biol 44, 898-914 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38328934
Transcatheter mitral valve replacement at an inflection point: lessons learned and the path forward. Ludwig, S. & Granada, J. F. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38327011
Current treatment and immunomodulation strategies in Acute Myocarditis. Ferone, E., Segev, A., Tempo, E., Gentile, P., Elsanhoury, A., Baggio, C., Artico, J., Bhatti, P., Scott, P., Bobbio, E., Merlo, M., Ameri, P., Sinagra, G., Tschope, C., Bromage, D. & Cannata, A. J Cardiovasc Pharmacol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38335530
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction. Gotthardt, M. & Lehnart, S. E. Cardiovasc Res 120, 220-222 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38333928
Predictors of non-recovery from fatigue and cognitive deficits after COVID-19: a prospective, longitudinal, population-based study. Hartung, T. J., Bahmer, T., Chaplinskaya-Sobol, I., Deckert, J., Endres, M., Franzpotter, K., Geritz, J., Haeusler, K. G., Hein, G., Heuschmann, P. U., Hopff, S. M., Horn, A., Keil, T., Krawczak, M., Krist, L., Lieb, W., Maetzler, C., Montellano, F. A., Morbach, C., Neumann, C., Nurnberger, C., Russ, A. K., Schmidbauer, L., Schmidt, S., Schreiber, S., Steigerwald, F., Stork, S., Zoller, T., Maetzler, W., Finke, C. & Group, N. S. EClinicalMedicine 69, 102456 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38333368
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants. Knauer, C., Haltern, H., Schoger, E., Kugler, S., Roos, L., Zelarayan, L. C., Hasenfuss, G., Zimmermann, W. H., Wollnik, B. & Cyganek, L. Mol Ther Nucleic Acids 35, 102123 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38333672
Age-Associated Differences in Recovery from Exercise-Induced Muscle Damage. Li, D. C. W., Rudloff, S., Langer, H. T., Norman, K. & Herpich, C. Cells 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38334647
Analysis of Epicardial Adipose Tissue Texture in Relation to Coronary Artery Calcification in PCCT: The EAT Signature! Mundt, P., Hertel, A., Tharmaseelan, H., Norenberg, D., Papavassiliu, T., Schoenberg, S. O., Froelich, M. F. & Ayx, I. Diagnostics (Basel) 14 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38337793
A 10-year Follow-up Study of Association Between Uric Acid and Adverse Cardiovascular Events in Patients With Coronary Artery Disease. Ndrepepa, G., Kufner, S., Cassese, S., Joner, M., Xhepa, E., Wiebe, J., Sager, H. B., Kessler, T., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Am J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38336081
Increased Expression of Proinflammatory Genes in Peripheral Blood Cells Is Associated with Cardiac Cachexia in Patients with Heart Failure with Reduced Ejection Fraction. Sandek, A., Gertler, C., Valentova, M., Jauert, N., Wallbach, M., Doehner, W., von Haehling, S., Anker, S. D., Fielitz, J. & Volk, H. D. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38337428
Adherence and potential factors of adherence to a resistance, coordination and endurance training in older retirement home residents over 6 months. Weiss, M., Mende, E., Schaller, N., Krusemark, H., Spanier, B., Zelger, O., Bischof, J., Haller, B., Halle, M. & Siegrist, M. Scand J Med Sci Sports 34, e14576 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38339790
It is time to think about further optimization of the echocardiographic assessment of left ventricular responses to mitral regurgitation. Dandel, M. Int J Cardiol 401, 131841 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38340988
Childhood maltreatment and sleep apnea: Findings from a cross-sectional general population study. Spitzer, C., Weihs, A., Ewert, R., Stubbe, B., Penzel, T., Fietze, I., Volzke, H. & Grabe, H. J. J Psychosom Res 178, 111600 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38340571
Challenges and pitfalls during CRT implantation in patients with persistent left superior vena cava. Akdis, D., Vogler, J., Sieren, M. M., Molitor, N., Sasse, T., Phan, H. L., Bartoli, L., Grosse, N., Saguner, A. M., Eriksson, U., Duru, F., Hofer, D., Breitenstein, A., Tilz, R. R. & Winnik, S. J Interv Card Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38345706
Complete revascularisation should be immediate in STEMI: pros and cons. Kastrati, A., Kessler, T., Rinaldi, R. & Brugaletta, S. EuroIntervention 20, e171-e173 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38343368
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse. Sommerfeld, L. C., Holmes, A. P., Yu, T. Y., O'Shea, C., Kavanagh, D. M., Pike, J. M., Wright, T., Syeda, F., Aljehani, A., Kew, T., Cardoso, V. R., Kabir, S. N., Hepburn, C., Menon, P. R., Broadway-Stringer, S., O'Reilly, M., Witten, A., Fortmueller, L., Lutz, S., Kulle, A., Gkoutos, G. V., Pavlovic, D., Arlt, W., Lavery, G. G., Steeds, R., Gehmlich, K., Stoll, M., Kirchhof, P. & Fabritz, L. J Physiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38345865
The Association Between C24:0/C16:0 Ceramide Ratio and Cardiorespiratory Fitness is Robust to Effect Modifications by Age and Sex. Zatloukal, J., Zylla, S., Markus, M. R. P., Ewert, R., Glaser, S., Volzke, H., Albrecht, D., Friedrich, N., Nauck, M., Peterson, L. R., Jiang, X., Schaffer, J. E., Felix, S. B., Dorr, M., Bahls, M. & Gross, S. Adv Biol (Weinh), e2300633 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38342586
Genomic attributes of airway commensal bacteria and mucosa. Cuthbertson, L., Lober, U., Ish-Horowicz, J. S., McBrien, C. N., Churchward, C., Parker, J. C., Olanipekun, M. T., Burke, C., McGowan, A., Davies, G. A., Lewis, K. E., Hopkin, J. M., Chung, K. F., O'Carroll, O., Faul, J., Creaser-Thomas, J., Andrews, M., Ghosal, R., Piatek, S., Willis-Owen, S. A. G., Bartolomaeus, T. U. P., Birkner, T., Dwyer, S., Kumar, N., Turek, E. M., William Musk, A., Hui, J., Hunter, M., James, A., Dumas, M. E., Filippi, S., Cox, M. J., Lawley, T. D., Forslund, S. K., Moffatt, M. F. & Cookson, W. O. C. Commun Biol 7, 171 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347162
Endothelial cells and macrophages as allies in the healthy and diseased brain. Denes, A., Hansen, C. E., Oezorhan, U., Figuerola, S., de Vries, H. E., Sorokin, L., Planas, A. M., Engelhardt, B. & Schwaninger, M. Acta Neuropathol 147, 38 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347307
Low on-clopidogrel ADP- and TRAP-6-induced platelet aggregation in patients with atrial fibrillation undergoing percutaneous coronary intervention: an observational pilot study. Gjermeni, D., Anfang, V., Vetter, H., Szabo, S., Hesselbarth, D., Gauchel, N., Siegel, P. M., Kaier, K., Kille, A., Franke, K., Leggewie, S., Trenk, D., Duerschmied, D., Bode, C., Westermann, D. & Olivier, C. B. J Thromb Thrombolysis 57, 361-369 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347374
Recommendations for optimal interdisciplinary management and healthcare settings for patients with rare neurological diseases. Graessner, H., Reinhard, C., Baumer, T., Baumgartner, A., Brockmann, K., Bruggemann, N., Bultmann, E., Erdmann, J., Heise, K., Hoglinger, G., Huning, I., Kaiser, F. J., Klein, C., Klopstock, T., Krageloh-Mann, I., Kraemer, M., Luedtke, K., Mucke, M., Musacchio, T., Nadke, A., Osmanovic, A., Ritter, G., Rose, K., Schippers, C., Schols, L., Schule, R., Schulz, J. B., Spross, J., Stasch, E., Wunderlich, G. & Munchau, A. Orphanet J Rare Dis 19, 62 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347616
Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy. Munoz, S., Bertolin, J., Jimenez, V., Jaen, M. L., Garcia, M., Pujol, A., Vila, L., Sacristan, V., Barbon, E., Ronzitti, G., El Andari, J., Tulalamba, W., Pham, Q. H., Ruberte, J., VandenDriessche, T., Chuah, M. K., Grimm, D., Mingozzi, F. & Bosch, F. Mol Metab 81, 101899 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38346589
Optogenetic confirmation of transverse-tubular membrane excitability in intact cardiac myocytes. Scardigli, M., Pasek, M., Santini, L., Palandri, C., Conti, E., Crocini, C., Campione, M., Loew, L. M., de Vries, A. A. F., Pijnappels, D. A., Pavone, F. S., Poggesi, C., Cerbai, E., Coppini, R., Kohl, P., Ferrantini, C. & Sacconi, L. J Physiol 602, 791-808 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38348881
Angiotensin Receptor-Neprilysin Inhibition (Sacubitril/Valsartan) Reduces Structural Arterial Stiffness in Middle-Aged Mice. Schellinger, I. N., Dannert, A., Hoffmann, A., Chodisetti, G., Mattern, K., Petzold, A., Kloting, N., Schuster, A., Wagenhauser, M. U., Emrich, F., Stumvoll, M., Hasenfuss, G. & Raaz, U. J Am Heart Assoc 13, e032641 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38348796
Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial. Sykes, R., Collison, D., Merkely, B., Kofoed, K. F., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Veselka, J., Sakalyte, G., Adic, N. C., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M., Ilnicka-Suckiel, M., Plank, F., Knuuti, J., Faria, R., Schroder, S., Berry, C., Saba, L., Ruzsics, B., Rieckmann, N., Kubiak, C., Hansen, K. S., Muller-Nordhorn, J., Maurovich-Horvat, P., Knudsen, A. D., Benedek, I., Orr, C., Valente, F. X., Zvaigzne, L., Horvath, M., Jankauskas, A., Adic, F., Woinke, M., Keane, S., Lecumberri, I., Thwaite, E., Laule, M., Kruk, M., Zivanic, A., Mancone, M., Kusmierz, D., Feuchtner, G., Pietila, M., Ribeiro, V. G., Drosch, T., Delles, C., Porcu, M., Fisher, M., Barany, T., Sorum, C., Aurelian, R., Kelly, S., Garcia Del Blanco, B., Rubio, A., Szilveszter, B., Abdulla, J., Rodean, I., Regan, S., Cuellar Calabria, H., Vecsey-Nagy, M., Jurlander, B., Hodas, R., Feger, S., Mohamed, M., Serna-Higuita, L. M., Neumann, K., Dreger, H., Rief, M., Wieske, V., Ferencik, M., Estrella, M., Bosserdt, M., Martus, P., Benedek, T., Dewey, M. & Group, D. T. Radiology 310, e230591 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38349247
Macrophages and endothelial cells in the neurovascular unit. Wenzel, J. & Schwaninger, M. Acta Neuropathol 147, 36 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347168
Sodium-glucose cotransporter-2 inhibitors in heart failure patients across the range of body mass index: a systematic review and meta-analysis of randomized controlled trials. Adamou, A., Chlorogiannis, D. D., Kyriakoulis, I. G., Stamatiou, I., Koukousaki, D., Kardoutsos, I., Sagris, D., Doehner, W. & Ntaios, G. Intern Emerg Med 19, 565-573 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38353880
Guideline-directed medical therapy assessment in heart failure patients undergoing percutaneous mitral valve repair. Kresoja, K. P., Adamo, M., Rommel, K. P., Stolz, L., Karam, N., Giannini, C., Melica, B., von Bardeleben, R. S., Butter, C., Horn, P., Praz, F., Kalbacher, D., Iliadis, C., Thiele, H., Hausleiter, J., Metra, M. & Lurz, P. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38351672
New race-free creatinine- and cystatin C-based equations for the estimation of glomerular filtration rate and association with cardiovascular mortality in the AtheroGene study. Ntaios, G., Brederecke, J., Ojeda, F. M., Zeller, T., Blankenberg, S. & Schnabel, R. B. Intern Emerg Med 19, 697-703 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38351263
Neurological Disorders in Takotsubo Syndrome: Clinical Phenotypes and Outcomes. Santoro, F., Nunez Gil, I. J., Arcari, L., Vitale, E., Martino, T., El-Battrawy, I., Guerra, F., Novo, G., Mariano, E., Musumeci, B., Cacciotti, L., Caldarola, P., Montisci, R., Ragnatela, I., Cetera, R., Vedia, O., Blanco, E., Pais, J. L., Martin, A., Perez-Castellanos, A., Salamanca, J., Bartolomucci, F., Akin, I., Thiele, H., Eitel, I., Stiermaier, T. & Brunetti, N. D. J Am Heart Assoc, e032128 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38353238
Sex-related differences in patients presenting with heart failure-related cardiogenic shock. Sundermeyer, J., Kellner, C., Beer, B. N., Besch, L., Dettling, A., Bertoldi, L. F., Blankenberg, S., Dauw, J., Dindane, Z., Eckner, D., Eitel, I., Graf, T., Horn, P., Jozwiak-Nozdrzykowska, J., Kirchhof, P., Kluge, S., Linke, A., Landmesser, U., Luedike, P., Lusebrink, E., Majunke, N., Mangner, N., Maniuc, O., Mobius-Winkler, S., Nordbeck, P., Orban, M., Pappalardo, F., Pauschinger, M., Pazdernik, M., Proudfoot, A., Kelham, M., Rassaf, T., Scherer, C., Schulze, P. C., Schwinger, R. H. G., Skurk, C., Sramko, M., Tavazzi, G., Thiele, H., Villanova, L., Morici, N., Winzer, E. B., Westermann, D. & Schrage, B. Clin Res Cardiol 113, 612-625 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38353681
The role of thyroid function in borderline personality disorder and schizophrenia: a Mendelian Randomisation study. Babajide, O., Kjaergaard, A. D., Deng, W., Kus, A., Sterenborg, R., Asvold, B. O., Burgess, S., Teumer, A., Medici, M., German Borderline Genomics, C., Ellervik, C., Nick, B., Deloukas, P. & Marouli, E. Borderline Personal Disord Emot Dysregul 11, 2 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355654
Phenotypic and genome-wide studies on dicarbonyls: major associations to glomerular filtration rate and gamma-glutamyltransferase activity. Harrer, P., Inderhees, J., Zhao, C., Schormair, B., Tilch, E., Gieger, C., Peters, A., Johren, O., Fleming, T., Nawroth, P. P., Berger, K., Hermesdorf, M., Winkelmann, J., Schwaninger, M. & Oexle, K. EBioMedicine 101, 105007 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38354534
Clinical and serological characterization of acute pleuropericarditis suggests an autoinflammatory pathogenesis and highlights risk factors for recurrent attacks. Kaudewitz, D., John, L., Meis, J., Frey, N., Lorenz, H. M., Leuschner, F. & Blank, N. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38358415
Vascular dysfunction and arterial hypertension in experimental celiac disease are mediated by gut-derived inflammation and oxidative stress. Keppeler, K., Pesi, A., Lange, S., Helmstadter, J., Strohm, L., Ubbens, H., Kuntic, M., Kuntic, I., Mihalikova, D., Vujacic-Mirski, K., Rosenberger, A., Kuster, L., Frank, C., Oelze, M., Finger, S., Zakrzewska, A., Verdu, E., Wild, J., Karbach, S., Wenzel, P., Wild, P., Leistner, D., Munzel, T., Daiber, A., Schuppan, D. & Steven, S. Redox Biol 70, 103071 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38354629
A single-cell time-lapse of mouse prenatal development from gastrula to birth. Qiu, C., Martin, B. K., Welsh, I. C., Daza, R. M., Le, T. M., Huang, X., Nichols, E. K., Taylor, M. L., Fulton, O., O'Day, D. R., Gomes, A. R., Ilcisin, S., Srivatsan, S., Deng, X., Disteche, C. M., Noble, W. S., Hamazaki, N., Moens, C. B., Kimelman, D., Cao, J., Schier, A. F., Spielmann, M., Murray, S. A., Trapnell, C. & Shendure, J. Nature (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355799
Reply: miRNAs, Endothelin-1 and Endothelial Glycocalyx Disorders in Shock Severity in Postoperative Cardiac Surgery Patients. Roeschl, T., Falk, V., Schoenrath, F. & Meyer, A. J Am Coll Cardiol 83, e73 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355252
Assessment of deep learning segmentation for real-time free-breathing cardiac magnetic resonance imaging at rest and under exercise stress. Schilling, M., Unterberg-Buchwald, C., Lotz, J. & Uecker, M. Sci Rep 14, 3754 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355969
From Gut to Heart: Role of Indole-3-Propionic Acid in HFpEF. Vacca, A. & Schiattarella, G. G. Circ Res 134, 390-392 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38359099
Association of serum magnesium with metabolic syndrome and the role of chronic kidney disease: A population-based cohort study with Mendelian randomization. Addin, N. S., Niedermayer, F., Thorand, B., Linseisen, J., Seissler, J., Peters, A. & Rospleszcz, S. Diabetes Obes Metab (2024). https://www.ncbi.nlm.nih.gov/pubmed/38361465
Alternative Renin-Angiotensin System. Bader, M., Muscha Steckelings, U., Alenina, N., Santos, R. A. S. & Ferrario, C. M. Hypertension (2024). https://www.ncbi.nlm.nih.gov/pubmed/38362781
NCoR1 limits angiogenic capacity by altering Notch signaling. Teichmann, T., Malacarne, P., Zehr, S., Gunther, S., Pfluger-Muller, B., Warwick, T. & Brandes, R. P. J Mol Cell Cardiol 188, 65-78 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38359551
Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration. Cordero, J., Elsherbiny, A., Wang, Y., Jürgensen, L., Constanty, F., Günther, S., Boerries, M., Heineke, J., Beisaw, A., Leuschner, F., Hassel, D. & Dobreva, G. Nucleic Acids Res 52, 4215-4233 (2024). Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration - PubMed (nih.gov)
Breathing danger: linking air pollution to cardiovascular disease and increased risk of abdominal aortic aneurysm. Hahad, O., Daiber, A. & Munzel, T. Eur Heart J 45, 1040-1042 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38366825
Patient satisfaction with coronary CT angiography versus invasive coronary angiography: results of a single-center randomized trial. Bosserdt, M., Wieske, V., Knebel, F., Mohamed, M. M. A., Feger, S., Dewey, M. & Schonenberger, E. Eur Radiol (2024). www.ncbi.nlm.nih.gov/pubmed/38367031
Tackling metabolic defects in HFpEF. Wang, R. & Schiattarella, G. G. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38367012
The ESR Essentials for the medical imaging community. Dewey, M. Eur Radiol 34, 2125-2126 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38369637
Use of class IC antiarrhythmic drugs in patients with structural heart disease and implantable cardioverter defibrillator. Zylla, M. M., Wolfes, J., Schleberger, R., Lawin, D., Kieser, M., Reinke, F., Eckardt, L., Rillig, A., Stellbrink, C., Thomas, D., Frey, N. & Lugenbiel, P. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38372753
Multivalent, calcium-independent binding of surfactant protein A and D to sulfated glycosaminoglycans of the alveolar epithelial glycocalyx. Avcibas, R., Vermul, A., Gluhovic, V., Boback, N., Arroyo, R., Kingma, P., Isasi-Campillo, M., Garcia-Ortega, L., Griese, M., Kuebler, W. M., Ochs, M., Lauster, D. & Lopez-Rodriguez, E. Am J Physiol Lung Cell Mol Physiol 326, L524-L538 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38375572
Generation of complex bone marrow organoids from human induced pluripotent stem cells. Frenz-Wiessner, S., Fairley, S. D., Buser, M., Goek, I., Salewskij, K., Jonsson, G., Illig, D., Zu Putlitz, B., Petersheim, D., Li, Y., Chen, P. H., Kalauz, M., Conca, R., Sterr, M., Geuder, J., Mizoguchi, Y., Megens, R. T. A., Linder, M. I., Kotlarz, D., Rudelius, M., Penninger, J. M., Marr, C. & Klein, C. Nat Methods (2024). https://www.ncbi.nlm.nih.gov/pubmed/38374263
Early action, lifelong impact: The crucial role of early detection, risk stratification and aggressive treatment of Familial Hypercholesterolemia. Sanin, V., Schmieder, R. S. & Koenig, W. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38376464
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., Rayner, N. W., Bocher, O., Arruda, A. L., Sonehara, K., Namba, S., Lee, S. S. K., Preuss, M. H., Petty, L. E., Schroeder, P., Vanderwerff, B., Kals, M., Bragg, F., Lin, K., Guo, X., Zhang, W., Yao, J., Kim, Y. J., Graff, M., Takeuchi, F., Nano, J., Lamri, A., Nakatochi, M., Moon, S., Scott, R. A., Cook, J. P., Lee, J. J., Pan, I., Taliun, D., Parra, E. J., Chai, J. F., Bielak, L. F., Tabara, Y., Hai, Y., Thorleifsson, G., Grarup, N., Sofer, T., Wuttke, M., Sarnowski, C., Gieger, C., Nousome, D., Trompet, S., Kwak, S. H., Long, J., Sun, M., Tong, L., Chen, W. M., Nongmaithem, S. S., Noordam, R., Lim, V. J. Y., Tam, C. H. T., Joo, Y. Y., Chen, C. H., Raffield, L. M., Prins, B. P., Nicolas, A., Yanek, L. R., Chen, G., Brody, J. A., Kabagambe, E., An, P., Xiang, A. H., Choi, H. 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Surgical or percutaneous treatment of mitral regurgitation: clip or cut? Lurz, P. & Kresoja, K. P. Eur Heart J 45, 950-951 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38379446
Definition, Classification, Diagnosis and Differential Diagnosis of Diabetes Mellitus: Update 2023. Pleus, S., Tytko, A., Landgraf, R., Heinemann, L., Werner, C., Muller-Wieland, D., Ziegler, A. G., Muller, U. A., Freckmann, G., Kleinwechter, H., Schleicher, E., Nauck, M. & Petersmann, A. Exp Clin Endocrinol Diabetes 132, 112-124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378016
Counting cells in motion by quantitative real-time magnetic particle imaging. Remmo, A., Kosch, O., Kampen, L., Ludwig, A., Wiekhorst, F. & Lowa, N. Sci Rep 14, 4253 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378785
Impact of the operative technique on mid- and long-term results following paediatric heart transplantation. Rosenthal, L. L., Grinninger, C., Pozza, R. D., Fischer, M., Zimmerling, L., Ulrich, S. M., Kari, F. A., Haas, N. A., Michel, S., Horer, J. & Hagl, C. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378979
New pharmacological agents and novel cardiovascular pharmacotherapy strategies in 2023. Tamargo, J., Agewall, S., Borghi, C., Ceconi, C., Cerbai, E., Dan, G. A., Ferdinandy, P., Grove, E. L., Rocca, B., Magavern, E., Sulzgruber, P., Semb, A. G., Sossalla, S., Niessner, A., Kaski, J. C. & Dobrev, D. Eur Heart J Cardiovasc Pharmacother (2024). https://www.ncbi.nlm.nih.gov/pubmed/38379024
European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke. Wardlaw, J. M., Chabriat, H., de Leeuw, F. E., Debette, S., Dichgans, M., Doubal, F., Jokinen, H., Katsanos, A. H., Ornello, R., Pantoni, L., Pasi, M., Pavlovic, A. M., Rudilosso, S., Schmidt, R., Staals, J., Taylor-Rowan, M., Hussain, S. & Lindgren, A. G. Eur Stroke J 9, 5-68 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38380638
Acute Kidney Injury After Heart Transplantation: Risk Factors and Clinical Outcomes. Welz, F., Schoenrath, F., Friedrich, A., Wloch, A., Stein, J., Hennig, F., Ott, S. C., O'Brien, B., Falk, V., Knosalla, C. & Just, I. A. J Cardiothorac Vasc Anesth 38, 1150-1160 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378323
TF-FVIIa PAR2-beta-Arrestin in Mouse Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection. Kespohl, M., Goetzke, C. C., Althof, N., Bredow, C., Kelm, N., Pinkert, S., Bukur, T., Bukur, V., Grunz, K., Kaur, D., Heuser, A., Mulleder, M., Sauter, M., Klingel, K., Weiler, H., Berndt, N., Gaida, M. M., Ruf, W. & Beling, A. Arterioscler Thromb Vasc Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38385286
First effectiveness data of lenvatinib and pembrolizumab as first-line therapy in advanced anaplastic thyroid cancer: a retrospective cohort study. Soll, D., Bischoff, P., Frisch, A., Jensen, M., Karadeniz, Z., Mogl, M. T., Horst, D., Penzkofer, T., Spranger, J., Keilholz, U. & Mai, K. BMC Endocr Disord 24, 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38383419
Thymic Atrophy and Immune Dysregulation in Infants with Complex Congenital Heart Disease. Bremer, S. J., Boxnick, A., Glau, L., Biermann, D., Joosse, S. A., Thiele, F., Billeb, E., May, J., Kolster, M., Hackbusch, R., Fortmann, M. I., Kozlik-Feldmann, R., Hubler, M., Tolosa, E., Sachweh, J. S. & Gieras, A. J Clin Immunol 44, 69 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38393459
Atrial fibrillation in the young: consider heritable conditions like short QT syndrome. Fabritz, L. & Lemoine, M. D. Cardiovasc Res 120, 437-439 (2024). Atrial fibrillation in the young: consider heritable conditions like short QT syndrome - PubMed (nih.gov)
Synchronous force and Ca(2+) measurements for repeated characterization of excitation-contraction coupling in human myocardium. Sun, Z., Lu, K., Kamla, C., Kameritsch, P., Seidel, T. & Dendorfer, A. Commun Biol 7, 220 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38388802
Personalised preinterventional risk stratification of mortality, length of stay and hospitalisation costs in transcatheter aortic valve implantation using a machine learning algorithm: a pilot trial. Zisiopoulou, M., Berkowitsch, A., Redlich, L., Walther, T., Fichtlscherer, S. & Leistner, D. M. Open Heart11 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38388188
The Evolving Role of Dendritic Cells in Atherosclerosis. Britsch, S., Langer, H., Duerschmied, D. & Becher, T. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38397127
Normative body mass-adjusted reference ranges of magnetic resonance imaging signs commonly used in diagnosing idiopathic intracranial hypertension in a healthy standard population. Kobrow, R., Gross, S., Fleischmann, R., Baldauf, J., Langner, S. & Strauss, S. Sci Rep 14, 4492 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38396059
Sex-specific associations of childhood maltreatment with obesity-related traits - The Study of Health in Pomerania (SHIP). Topfer, P., Siewert-Markus, U., Klinger-Konig, J., Grabe, H. J., Stracke, S., Dorr, M., Volzke, H., Ittermann, T. & Markus, M. R. P. Child Abuse Negl 149, 106704 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38395019
Pulmonary Vein Isolation Followed by Biatrial Ablation of Rotational Activity in Patients with Persistent Atrial Fibrillation: Results of the Cryo-Vest Study. Weipert, K. F., Hutter, J., Kuniss, M., Kahle, P., Yogarajah, J., Hain, A., Sperzel, J., Berkowitsch, A., Hamm, C. W. & Neumann, T. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38398432
ATF6 protects against protein misfolding during cardiac hypertrophy. Hofmann, C., Aghajani, M., Alcock, C. D., Blackwood, E. A., Sandmann, C., Herzog, N., Gross, J., Plate, L., Wiseman, R. L., Kaufman, R. J., Katus, H. A., Jakobi, T., Volkers, M., Glembotski, C. C. & Doroudgar, S. J Mol Cell Cardiol 189, 12-24 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38401179
The Chronic Dilemma of Chronic Total Occlusion Revascularization. Cassese, S. & Kastrati, A. Am J Cardiol 216, 95-97 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38401654
Circulating miR-let7a levels predict future diagnosis of chronic thromboembolic pulmonary hypertension. Kenneweg, F., Hobohm, L., Bang, C., Gupta, S. K., Xiao, K., Thum, S., Ten Cate, V., Rapp, S., Hasenfuss, G., Wild, P., Konstantinides, S., Wachter, R., Lankeit, M. & Thum, T. Sci Rep 14, 4514 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38402278
Effect of SGLT-2 inhibitors on arrhythmia events: insight from an updated secondary analysis of > 80,000 patients (the SGLT2i-Arrhythmias and Sudden Cardiac Death). Liao, J., Ebrahimi, R., Ling, Z., Meyer, C., Martinek, M., Sommer, P., Futyma, P., Di Vece, D., Schratter, A., Acou, W. J., Zhu, L., Kiuchi, M. G., Liu, S., Yin, Y., Purerfellner, H., Templin, C. & Chen, S. Cardiovasc Diabetol 23, 78 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38402177
Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis. Stone, G. W., Christiansen, E. H., Ali, Z. A., Andreasen, L. N., Maehara, A., Ahmad, Y., Landmesser, U. & Holm, N. R. Lancet 403, 824-837 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38401549
Histological assessment of cardiac amyloidosis in patients undergoing transcatheter aortic valve replacement. Beuthner, B. E., Elkenani, M., Evert, K., Mustroph, J., Jacob, C. F., Paul, N. B., Beissbarth, T., Zeisberg, E. M., Schnelle, M., Puls, M., Hasenfuss, G. & Toischer, K. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38407567
Body composition markers are associated with changes in inflammatory markers but not vice versa: A bi-directional longitudinal analysis in a population-based sample. Bibi, S., Naeem, M., Mahmoud Mousa, M. F., Bahls, M., Dorr, M., Friedrich, N., Nauck, M., Bulow, R., Volzke, H., Markus, M. R. & Ittermann, T. Nutr Metab Cardiovasc Dis 34, 1166-1174 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38403482
Lactate and Lactate Clearance as Predictors of One-Year Survival in Extracorporeal Cardiopulmonary Resuscitation - An International, Multicentre Cohort Study. Thevathasan, T., Gregers, E., Rasalingam Mork, S., Degbeon, S., Linde, L., Bonding Andreasen, J., Smerup, M., Eifer Moller, J., Hassager, C., Laugesen, H., Dreger, H., Brand, A., Balzer, F., Landmesser, U., Juhl Terkelsen, C., Flensted Lassen, J., Skurk, C. & Soholm, H. Resuscitation, 110149 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38403182
Sex Differences in Outcomes of Acute Myocardial Injury After Stroke. Rosso, M., Stengl, H., Ganeshan, R., Hellwig, S., Klammer, M. G., von Rennenberg, R., Bohme, S., Nolte, C. H., Audebert, H. J., Endres, M., Kasner, S. E. & Scheitz, J. F. J Am Heart Assoc 13, e032755 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38410952
Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial. Group, D. T., Bosserdt, M., Serna-Higuita, L. M., Feuchtner, G., Merkely, B., Kofoed, K. F., Benedek, T., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Stechovsky, C., Sakalyte, G., Adic, N. C., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M., Ilnicka-Suckiel, M., Plank, F., Knuuti, J., Faria, R., Schroder, S., Berry, C., Saba, L., Ruzsics, B., Rieckmann, N., Kubiak, C., Hansen, K. S., Muller-Nordhorn, J., Szilveszter, B., Sigvardsen, P. E., Benedek, I., Orr, C., Valente, F. X., Zvaigzne, L., Suchanek, V., Jankauskas, A., Adic, F., Woinke, M., Hensey, M., Lecumberri, I., Thwaite, E., Laule, M., Kruk, M., Neskovic, A. N., Mancone, M., Kusmierz, D., Pietila, M., Ribeiro, V. G., Drosch, T., Delles, C., Porcu, M., Fisher, M., Boussoussou, M., Kragelund, C., Aurelian, R., Kelly, S., Garcia Del Blanco, B., Rubio, A., Maurovich-Horvat, P., Hove, J. D., Rodean, I., Regan, S., Cuellar-Calabria, H., Molnar, L., Larsen, L., Hodas, R., Napp, A. E., Haase, R., Feger, S., Mohamed, M., Neumann, K., Dreger, H., Rief, M., Wieske, V., Estrella, M., Martus, P., Sox, H. C. & Dewey, M. JAMA Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38416472
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9. Trogisch, F. A., Abouissa, A., Keles, M., Birke, A., Fuhrmann, M., Dittrich, G. M., Weinzierl, N., Wink, E., Cordero, J., Elsherbiny, A., Martin-Garrido, A., Grein, S., Hemanna, S., Hofmann, E., Nicin, L., Bibli, S. I., Airik, R., Kispert, A., Kist, R., Quanchao, S., Kurschner, S. W., Winkler, M., Gretz, N., Mogler, C., Korff, T., Koch, P. S., Dimmeler, S., Dobreva, G. & Heineke, J. Sci Transl Med 16, eabq4581 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38416842
Higher Parametric Thyroid Feedback Quantile-based Index is a predictor of type 2 diabetes in a German population sample. Laclaustra, M., Alonso-Ventura, V., Schipf, S., Lou-Bonafonte, J. M., Dorr, M., Trincado-Aznar, P., Volzke, H., Nauck, M., Civeira, F. & Ittermann, T. J Clin Endocrinol Metab (2024). https://www.ncbi.nlm.nih.gov/pubmed/38421022
Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart. Waheed-Ullah, Q., Wilsdon, A., Abbad, A., Rochette, S., Bu'Lock, F., Hitz, M. P., Dombrowsky, G., Cuello, F., Brook, J. D. & Loughna, S. J Anat (2024). https://www.ncbi.nlm.nih.gov/pubmed/38419169
Novel drug therapies for atrial fibrillation. Wiedmann, F. & Schmidt, C. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38418746
January
Paper of the Month
In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector
DZHK authors: Patrick Laurette, Can Cao, Deepak Ramanujam, Lisa Weiss, Eileen Furlong, Flavia de Rezende, Stefan Engelhardt, Ralf Gilsbach. Circulation Research 2024.
mRNA vaccines for COVID-19 are safe and clinically effective in patients with cardiac amyloidosis. Barzen, G., Rieber, F., Stangl, K., Hahn, K. & Spethmann, S. Vaccine (2023). https://www.ncbi.nlm.nih.gov/pubmed/38158299
The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. Carlantoni, C., Liekfeld, L. M. H., Hemkemeyer, S. A., Schreier, D., Saygi, C., Kurelic, R., Cardarelli, S., Kalucka, J., Schulte, C., Beerens, M., Mailer, R. K., Schaffer, T. E., Naro, F., Pellegrini, M., Nikolaev, V. O., Renne, T. & Frye, M. Dev Cell (2023). https://www.ncbi.nlm.nih.gov/pubmed/38159569
Efficacy of empagliflozin in heart failure with preserved ejection fraction according to frailty status in EMPEROR-Preserved. Coats, A. J. S., Butler, J., Tsutsui, H., Doehner, W., Filippatos, G., Ferreira, J. P., Bohm, M., Chopra, V. K., Verma, S., Nordaby, M., Iwata, T., Nitta, D., Ponikowski, P., Zannad, F., Packer, M. & Anker, S. D. J Cachexia Sarcopenia Muscle (2023). https://www.ncbi.nlm.nih.gov/pubmed/38158636
Impact of Clinical Phenogroup Diversity and Multiplicity: Impact on Mechanisms of Exercise Intolerance in Heart Failure with Preserved Ejection Fraction. Larson, K., Omar, M., Sorimachi, H., Omote, K., Alogna, A., Popovic, D., Tada, A., Doi, S., Naser, J., Reddy, Y. N. V., Redfield, M. M. & Borlaug, B. A. Eur J Heart Fail (2023). https://www.ncbi.nlm.nih.gov/pubmed/38156712
Heparin dosing in patients with Impella-supported cardiogenic shock. Vandenbriele, C., M'Pembele, R., Dannenberg, L., Metzen, D., Zako, S., Helten, C., Mourikis, P., Ignatov, D., Huhn, R., Balthazar, T., Adriaenssens, T., Vanassche, T., Meyns, B., Panoulas, V., Monteagudo-Vela, M., Arachchillage, D., Janssens, S., Scherer, C., Orban, M., Petzold, T., Horn, P., Jung, C., Zeus, T., Price, S., Westenfeld, R., Kelm, M. & Polzin, A. Int J Cardiol, 131690 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38160912
RNA-binding proteins in cardiovascular biology and disease: the beat goes on. Volkers, M., Preiss, T. & Hentze, M. W. Nat Rev Cardiol 21, 361-378 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38163813
Real-time cardiovascular magnetic resonance imaging for non-invasive characterisation of heart failure with preserved ejection fraction: final outcomes of the HFpEF stress trial. Backhaus, S. J., Schulz, A., Lange, T., Schmidt-Schweda, L. S., Evertz, R., Kowallick, J., Hasenfuss, G. & Schuster, A. Clin Res Cardiol 113, 496-508 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38170248
Toward accurate and fast velocity quantification with 3D ultrashort TE phase-contrast imaging. Degenhardt, K., Schmidt, S., Aigner, C. S., Kratzer, F. J., Seiter, D. P., Mueller, M., Kolbitsch, C., Nagel, A. M., Wieben, O., Schaeffter, T., Schulz-Menger, J. & Schmitter, S. Magn Reson Med 91, 1994-2009 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38174601
Loss of cardiac mitochondrial complex I persulfidation impairs NAD(+) homeostasis in aging. Drekolia, M. K., Karantanou, C., Wittig, I., Li, Y., Fuhrmann, D. C., Brune, B., Katsouda, A., Hu, J., Papapetropoulos, A. & Bibli, S. I. Redox Biol 69, 103014 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38171255
Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes. Paasche, A., Wiedmann, F., Kraft, M., Seibertz, F., Herlt, V., Blochberger, P. L., Javorszky, N., Beck, M., Weirauch, L., Seeger, T., Blank, A., Haefeli, W. E., Arif, R., Meyer, A. L., Warnecke, G., Karck, M., Voigt, N., Frey, N. & Schmidt, C. Basic Res Cardiol 119, 93-112 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38170280
Cyclophilin A is a ligand for RAGE in thrombo-inflammation. Seizer, P., von Ungern-Sternberg, S. N. I., Haug, V., Dicenta, V., Rosa, A., Butt, E., Nothel, M., Rohlfing, A. K., Sigle, M., Nawroth, P. P., Nussbaum, C., Sperandio, M., Kusch, C., Meub, M., Sauer, M., Munzer, P., Bieber, K., Stanger, A., Mack, A. F., Huber, R., Brand, K., Lehners, M., Feil, R., Poso, A., Krutzke, K., Schaffer, T. E., Nieswandt, B., Borst, O., May, A. E., Zernecke, A., Gawaz, M. & Heinzmann, D. Cardiovasc Res 120, 385-402 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38175781
Biomarkers in Primary Prevention: Steps beyond Established Risk Scores. Zeller, T., Shrivastava, A. & Karakas, M. Clin Chem 70, 355-357 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38169350
ILC2-mediated immune crosstalk in chronic (vascular) inflammation. Kral, M., van der Vorst, E. P. C., Surnov, A., Weber, C. & Doring, Y. Front Immunol 14, 1326440 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38179045
Treatment With an Interatrial Shunt in Heart Failure: 1-Year Outcomes of the PRELIEVE Study. Paitazoglou, C., Bergmann, M. W., Kilicaslan, B., Kilic, T., Bartunek, J., Pfister, R., Iliadis, C., Kaya, E. B. & Ozdemir, R. JACC Heart Fail 12, 591-594 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38180430
Noninvasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM. Rapohn, M., Cyganek, L., Voigt, N., Hasenfuss, G., Lehnart, S. E. & Wegener, J. W. Am J Physiol Heart Circ Physiol 326, H599-H611 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38180453
Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT). Roubille, F., Bouabdallaoui, N., Kouz, S., Waters, D. D., Diaz, R., Maggioni, A. P., Pinto, F. J., Gregoire, J. C., Gamra, H., Kiwan, G. S., Berry, C., Lopez-Sendon, J., Koenig, W., Delorme, L., Elbaz, M., Coste, P., Provencher, M., Bassevitch, Z., Blondeau, L., L'Allier, P. L., Guertin, M. C. & Tardif, J. C. Diabetes Care 47, 467-470 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38181203
Left-Ventricular Unloading With Impella During Refractory Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis. Thevathasan, T., Fureder, L., Fechtner, M., Mork, S. R., Schrage, B., Westermann, D., Linde, L., Gregers, E., Andreasen, J. B., Gaisendrees, C., Unoki, T., Axtell, A. L., Takeda, K., Vinogradsky, A. V., Goncalves-Teixeira, P., Lemaire, A., Alonso-Fernandez-Gatta, M., Sern Lim, H., Garan, A. R., Bindra, A., Schwartz, G., Landmesser, U. & Skurk, C. Crit Care Med 52, 464-474 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38180032
Polypharmacy in patients with multiple sclerosis and the impact on levels of care and therapy units. Bruggemann, F., Gross, S., Susse, M., Hok, P., Strauss, S., Ziemssen, T., Frahm, N., Zettl, U. K. & Grothe, M. Front Neurol 14, 1330066 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38187151
Contact force sensing manual catheter versus remote magnetic navigation ablation of atrial fibrillation: a single-center comparison. Schlögl, S., Schlögl, K. S., Bengel, P., Haarmann, H., Bergau, L., Rasenack, E., Hasenfuss, G. & Zabel, M. Heart Vessels 39, 427-437 (2024). Contact force sensing manual catheter versus remote magnetic navigation ablation of atrial fibrillation: a single-center comparison - PubMed (nih.gov)
Control of cardiac contractions using Cre-lox and degron strategies in zebrafish. Juan, T., Bellec, M., Cardoso, B., Athea, H., Fukuda, N., Albu, M., Gunther, S., Looso, M. & Stainier, D. Y. R. Proc Natl Acad Sci U S A 121, e2309842121 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38194447
[Postmortem genetic analysis following sudden cardiac death : Background, approach, and future]. Kauferstein, S. & Beckmann, B. M. Herzschrittmacherther Elektrophysiol 35, 31-38 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38197940
Cardiovascular multimodality imaging in women. A scientific statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC. Almeida, A. G., Grapsa, J., Gemelli, A., Bucciarelli-Ducci, C., Gerber, B., Ajmone-Marsan, N., Bernard, A., Donal, E., Dweck, M. R., Haugaa, K. H., Hristova, K., Maceira, A., Mandoli, G. E., Mulvagh, S., Morrone, D., Plonska-Gosciniak, E., Sade, L. E., Schivalkar, B., Schulz-Menger, J., Shaw, L., Sitges, M., von Kemp, B., Pinto, F. J., Edvardsen, T., Petersen, S. E. & Cosyns, B. Eur Heart J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38198766
Characterization of Commercially Available Human Primary Alveolar Epithelial Cells. Herbst, C. J., Lopez-Rodriguez, E., Gluhovic, V., Schulz, S., Brandt, R., Timm, S., Abledu, J., Falivene, J., Pennitz, P., Kirsten, H., Nouailles, G., Witzenrath, M., Ochs, M. & Kuebler, W. M. Am J Respir Cell Mol Biol 70, 339-350 (2024).
Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli. Naeem, Z., Zukunft, S., Huard, A., Hu, J., Hammock, B. D., Weigert, A., Fromel, T. & Fleming, I. Biomed Pharmacother 171, 116127 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38198951
Detection of hypoplastic left heart syndrome anatomy from cardiovascular magnetic resonance images using machine learning. Gabbert, D. D., Petersen, L., Burleigh, A., Grazioli, S. B., Krupickova, S., Koch, R., Uebing, A. S., Santarossa, M. & Voges, I. MAGMA (2024). https://www.ncbi.nlm.nih.gov/pubmed/38214799
Systematic review and meta-analysis for the value of cardiac magnetic resonance strain to predict cardiac outcomes. Korosoglou, G., Sagris, M., Andre, F., Steen, H., Montenbruck, M., Frey, N. & Kelle, S. Sci Rep 14, 1094 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38212323
Contemporary risk assessment of aortic root injury for new-generation balloon-expandable transcatheter heart valves. Kim, W. K., Charitos, E., Renker, M., Hamm, C., Seidler, T., Hamm, C. W., Choi, Y. H. & Sossalla, S. Can J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38215971
A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise. Methi, A., Islam, M. R., Kaurani, L., Sakib, M. S., Kruger, D. M., Pena, T., Burkhardt, S., Liebetanz, D. & Fischer, A. Mol Neurobiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38217668
Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch clamp assay. Thomson, K. L., Jiang, C., Richardson, E., Westphal, D. S., Burkard, T., Wolf, C. M., Vatta, M., Harrison, S. M., Ingles, J., Bezzina, C. R., Kroncke, B. M., Vandenberg, J. I. & Ng, C. A. HGG Adv, 100270 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38219013
Etiologies and predictors of mortality in an all-comer population of patients with non-ischemic heart failure. Göbel, S., Braun, A. S., Hahad, O., von Henning, U., Brandt, M., Keller, K., Gaida, M. M., Gori, T., Schultheiss, H. P., Escher, F., Münzel, T. & Wenzel, P. Clin Res Cardiol 113, 737-749 (2024). Etiologies and predictors of mortality in an all-comer population of patients with non-ischemic heart failure - PubMed (nih.gov)
Deep learning to estimate impaired glucose metabolism from Magnetic Resonance Imaging of the liver: An opportunistic population screening approach. Michel, L. J., Rospleszcz, S., Reisert, M., Rau, A., Nattenmueller, J., Rathmann, W., Schlett, C. L., Peters, A., Bamberg, F. & Weiss, J. PLOS Digit Health 3, e0000429 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38227569
STIGMA: Single-cell tissue-specific gene prioritization using machine learning. Balachandran, S., Prada-Medina, C. A., Mensah, M. A., Kakar, N., Nagel, I., Pozojevic, J., Audain, E., Hitz, M. P., Kircher, M., Sreenivasan, V. K. A. & Spielmann, M. Am J Hum Genet 111, 338-349 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38228144
Mask Continuous Positive Airway Pressure Increases Diaphragm Thickening Fraction in Healthy Subjects. Lindner, S., Teichert, J., Hoermann, C., Michels, J. D., Herth, F. J. F., Duerschmied, D. & Britsch, S. Respiration, 1-5 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38228112
Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function. Gersch, S., Lange, T., Beuthner, B. E., Elkenani, M., Paul, N., Schnelle, M., Zeisberg, E., Puls, M., Hasenfuss, G., Schuster, A. & Toischer, K. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38236417
Endogenous Nitric Oxide Can Enhance Oxidative Stress Caused by Air Pollutants and Explain Higher Susceptibility of Individuals with Inflammatory Disorders. Lelieveld, S., Lelieveld, J., Mishra, A., Daiber, A., Pozzer, A., Poschl, U. & Berkemeier, T. Environ Sci Technol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38235527
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements. Scholz, M., Horn, K., Pott, J., Wuttke, M., Kuhnapfel, A., Nasr, M. K., Kirsten, H., Li, Y., Hoppmann, A., Gorski, M., Ghasemi, S., Li, M., Tin, A., Chai, J. F., Cocca, M., Wang, J., Nutile, T., Akiyama, M., Asvold, B. O., Bansal, N., Biggs, M. L., Boutin, T., Brenner, H., Brumpton, B., Burkhardt, R., Cai, J., Campbell, A., Campbell, H., Chalmers, J., Chasman, D. I., Chee, M. L., Chee, M. L., Chen, X., Cheng, C. Y., Cifkova, R., Daviglus, M., Delgado, G., Dittrich, K., Edwards, T. L., Endlich, K., Michael Gaziano, J., Giri, A., Giulianini, F., Gordon, S. D., Gudbjartsson, D. F., Hallan, S., Hamet, P., Hartman, C. A., Hayward, C., Heid, I. M., Hellwege, J. N., Holleczek, B., Holm, H., Hutri-Kahonen, N., Hveem, K., Isermann, B., Jonas, J. B., Joshi, P. K., Kamatani, Y., Kanai, M., Kastarinen, M., Khor, C. C., Kiess, W., Kleber, M. E., Korner, A., Kovacs, P., Krajcoviechova, A., Kramer, H., Kramer, B. K., Kuokkanen, M., Kahonen, M., Lange, L. A., Lash, J. P., Lehtimaki, T., Li, H., Lin, B. M., Liu, J., Loeffler, M., Lyytikainen, L. P., Magnusson, P. K. E., Martin, N. G., Matsuda, K., Milaneschi, Y., Mishra, P. P., Mononen, N., Montgomery, G. W., Mook-Kanamori, D. O., Mychaleckyj, J. C., Marz, W., Nauck, M., Nikus, K., Nolte, I. M., Noordam, R., Okada, Y., Olafsson, I., Oldehinkel, A. J., Penninx, B., Perola, M., Pirastu, N., Polasek, O., Porteous, D. J., Poulain, T., Psaty, B. M., Rabelink, T. J., Raffield, L. M., Raitakari, O. T., Rasheed, H., Reilly, D. F., Rice, K. M., Richmond, A., Ridker, P. M., Rotter, J. I., Rudan, I., Sabanayagam, C., Salomaa, V., Schneiderman, N., Schottker, B., Sims, M., Snieder, H., Stark, K. J., Stefansson, K., Stocker, H., Stumvoll, M., Sulem, P., Sveinbjornsson, G., Svensson, P. O., Tai, E. S., Taylor, K. D., Tayo, B. O., Teren, A., Tham, Y. C., Thiery, J., Thio, C. H. L., Thomas, L. F., Tremblay, J., Tonjes, A., van der Most, P. J., Vitart, V., Volker, U., Wang, Y. X., Wang, C., Wei, W. B., Whitfield, J. B., Wild, S. H., Wilson, J. F., Winkler, T. W., Wong, T. Y., Woodward, M., Sim, X., Chu, A. Y., Feitosa, M. F., Thorsteinsdottir, U., Hung, A. M., Teumer, A., Franceschini, N., Parsa, A., Kottgen, A., Schlosser, P. & Pattaro, C. Nat Commun 15, 586 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38233393
Assessment of the cardiac output at rest and during exercise stress using real-time cardiovascular magnetic resonance imaging in HFpEF-patients. Schulz, A., Mittelmeier, H., Wagenhofer, L., Backhaus, S. J., Lange, T., Evertz, R., Kutty, S., Kowallick, J. T., Hasenfuss, G. & Schuster, A. Int J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38236362
C-reactive protein modifies lipoprotein(a)-related risk for coronary heart disease: the BiomarCaRE project. Arnold, N., Blaum, C., Gossling, A., Brunner, F. J., Bay, B., Ferrario, M. M., Brambilla, P., Cesana, G., Leoni, V., Palmieri, L., Donfrancesco, C., Padro, T., Andersson, J., Jousilahti, P., Ojeda, F., Zeller, T., Linneberg, A., Soderberg, S., Iacoviello, L., Gianfagna, F., Sans, S., Veronesi, G., Thorand, B., Peters, A., Tunstall-Pedoe, H., Kee, F., Salomaa, V., Schnabel, R. B., Kuulasmaa, K., Blankenberg, S., Koenig, W. & Waldeyer, C. Eur Heart J45, 1043-1054 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38240386
The obesity paradigm on outcome in heart failure with reduced ejection fraction. Doehner, W., Akyea, R. K. & Ntaios, G. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38240033
[Update on the treatment of aortic valve stenosis in symptomatic and asymptomatic patients]. Rheude, T., Pellegrini, C., Xhepa, E. & Joner, M. Herz (2024). https://www.ncbi.nlm.nih.gov/pubmed/38240775
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Santamans, A. M., Cicuendez, B., Mora, A., Villalba-Orero, M., Rajlic, S., Crespo, M., Vo, P., Jerome, M., Macias, A., Lopez, J. A., Leiva, M., Rocha, S. F., Leon, M., Rodriguez, E., Leiva, L., Pintor Chocano, A., Garcia Lunar, I., Garcia-Alvarez, A., Hernansanz-Agustin, P., Peinado, V. I., Barbera, J. A., Ibanez, B., Vazquez, J., Spinelli, J. B., Daiber, A., Oliver, E. & Sabio, G. Sci Adv10, eadk6524 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38241373
Artificial intelligence-derived risk score for mortality in secondary mitral regurgitation treated by transcatheter edge-to-edge repair: the EuroSMR risk score. Hausleiter, J., Lachmann, M., Stolz, L., Bedogni, F., Rubbio, A. P., Estevez-Loureiro, R., Raposeiras-Roubin, S., Boekstegers, P., Karam, N., Rudolph, V. & Euro, S. M. R. I. Eur Heart J 45, 922-936 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38243773
An altered plasma lipidome-phenome network characterizes heart failure with preserved ejection fraction. Jovanovic, N., Foryst-Ludwig, A., Klose, C., da Conceicao, C. R., Alasfar, L., Birkner, T., Forslund, S. K., Kintscher, U. & Edelmann, F. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38243357
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts. Shumliakivska, M., Luxan, G., Hemmerling, I., Scheller, M., Li, X., Muller-Tidow, C., Schuhmacher, B., Sun, Z., Dendorfer, A., Debes, A., Glaser, S. F., Muhly-Reinholz, M., Kirschbaum, K., Hoffmann, J., Nagel, E., Puntmann, V. O., Cremer, S., Leuschner, F., Abplanalp, W. T., John, D., Zeiher, A. M. & Dimmeler, S. Nat Commun 15, 606 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38242884
Single muscle assessment for diagnosing sarcopenia is inherently flawed. von Haehling, S. J Stroke Cerebrovasc Dis, 107533 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38242814
Layer-specific fast strain-encoded cardiac magnetic resonance imaging aids in the identification and discrimination of acute myocardial injury: a prospective proof-of-concept study. Weberling, L. D., Albert, D., Ochs, A., Ochs, M., Siry, D., Salatzki, J., Giannitsis, E., Frey, N., Riffel, J. & Andre, F. J Cardiovasc Magn Reson, 101001 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38244931
Neuromodulation interventions in the management of heart failure. Abdin, A., Lauder, L., Fudim, M., Abraham, W. T., Anker, S. D., Bohm, M. & Mahfoud, F. Eur J Heart Fail (2024). www.ncbi.nlm.nih.gov/pubmed/38247193
MRAS in coronary artery disease-Unchartered territory. Shah, P. W., Reinberger, T., Hashmi, S., Aherrahrou, Z. & Erdmann, J. IUBMB Life (2024). https://www.ncbi.nlm.nih.gov/pubmed/38251784
Comparison of Two Contemporary Quantitative Atherosclerotic Plaque Assessment Tools for Coronary Computed Tomography Angiography: Single-Center Analysis and Multi-Center Patient Cohort Validation. Weichsel, L., Giesen, A., Andre, F., Renker, M., Baumann, S., Breitbart, P., Beer, M., Maurovitch-Horvat, P., Szilveszter, B., Vattay, B., Buss, S. J., Marwan, M., Giannopoulos, A. A., Kelle, S., Frey, N. & Korosoglou, G. Diagnostics (Basel) 14 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38248031
Lipoprotein(a) and cardiovascular disease: sifting the evidence to guide future research. Kamstrup, P. R., Neely, R. D. G., Nissen, S., Landmesser, U., Haghikia, A., Costa-Scharplatz, M., Abbas, C. & Nordestgaard, B. G. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38253342
Correction: Samak et al. Dysregulation of Kruppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482. Samak, M., Kues, A., Kaltenborn, D., Klosener, L., Mietsch, M., Germena, G. & Hinkel, R. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38256279
An Overview of Different Vitamin D Compounds in the Setting of Adiposity. Spyksma, E. E., Alexandridou, A., Mai, K., Volmer, D. A. & Stokes, C. S. Nutrients 16 (2024). www.ncbi.nlm.nih.gov/pubmed/38257127
Circulating microRNA miR-425-5p Associated with Brain White Matter Lesions and Inflammatory Processes. Van der Auwera, S., Ameling, S., Wittfeld, K., Frenzel, S., Bulow, R., Nauck, M., Volzke, H., Volker, U. & Grabe, H. J. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38255959
Mechanical Circulatory Support Strategies in Takotsubo Syndrome with Cardiogenic Shock: A Systematic Review. von Mackensen, J. K. R., Zwaans, V. I. T., El Shazly, A., Van Praet, K. M., Heck, R., Starck, C. T., Schoenrath, F., Potapov, E. V., Kempfert, J., Jacobs, S., Falk, V. & Wert, L. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38256608
Non-vitamin-K-antagonist oral anticoagulants (NOACs) after acute myocardial infarction: a network meta-analysis. Al Said, S., Kaier, K., Sumaya, W., Alsaid, D., Duerschmied, D., Storey, R. F., Gibson, C. M., Westermann, D. & Alabed, S. Cochrane Database Syst Rev1, CD014678 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38264795
European Society of Cardiology Quality indicators for the care and outcomes of adults undergoing transcatheter aortic valve implantation. Ali, N., Aktaa, S., Younsi, T., Beska, B., Batra, G., Blackman, D. J., James, S., Ludman, P., Mamas, M. A., Abdel-Wahab, M., Borregaard, B., Iung, B., Joner, M., Kunadian, V., Modine, T., Neylon, A., Petronio, A. S., Pibarot, P., Popescu, B. A., Sabate, M., Stortecky, S., Teles, R. C., Treede, H. & Gale, C. P. Eur Heart J Qual Care Clin Outcomes (2024). https://www.ncbi.nlm.nih.gov/pubmed/38262740
Disturbed atrial metabolism, shear stress, and cardiac load AF after ablation: AXAFA biomolecule study. Chua, W., Khashaba, A., Canagarajah, H., Nielsen, J. C., di Biase, L., Haeusler, K. G., Hindricks, G., Mont, L., Piccini, J., Schnabel, R. B., Schotten, U., Wienhues-Thelen, U. H., Zeller, T., Fabritz, L. & Kirchhof, P. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38266130
Patterns in acute aortic dissection and a connection to meteorological conditions in Germany. Kurz, S. D., Mahlke, H., Graw, K., Prasse, P., Falk, V., Knosalla, C. & Matzarakis, A. PLoS One 19, e0296794 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38265976
Aspirin loading and coronary no-reflow after percutaneous coronary intervention in patients with acute myocardial infarction. Ndrepepa, G., Cassese, S., Xhepa, E., Joner, M., Sager, H. B., Kufner, S., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Eur J Clin Invest, e14173 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38264959
Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes. Schmidt, J., Kaulfuss, S., Ott, H., Gaubert, M., Reintjes, N., Bremmer, F., Dreha-Kulaczewski, S., Stroebel, P., Yigit, G. & Wollnik, B. Hum Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/38265560
Efficacy and safety of CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: Rationale and design of the HF-REVERT trial. Bauersachs, J., Solomon, S. D., Anker, S. D., Antorrena-Miranda, I., Batkai, S., Viereck, J., Rump, S., Filippatos, G., Granzer, U., Ponikowski, P., de Boer, R. A., Vardeny, O., Hauke, W. & Thum, T. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38269451
Serotonin Transporter-dependent Histone Serotonylation in Placenta Contributes to the Neurodevelopmental Transcriptome. Chan, J. C., Alenina, N., Cunningham, A. M., Ramakrishnan, A., Shen, L., Bader, M. & Maze, I. J Mol Biol 436, 168454 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38266980
Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD-results from COSYCONET. Fahndrich, S., Herr, C., Teuteberg, S., Alter, P., Sohler, S., Soriano, D., Classen, J., Adams, J., Weinhold, V., Watz, H., Waschki, B., Zeller, T., Eichenlaub, M., Trudzinski, F. C., Michels, J. D., Omlor, A., Seiler, F., Moneke, I., Biertz, F., Stolz, D., Welte, T., Kauczor, H. U., Kahnert, K., Jorres, R. A., Vogelmeier, C. F., Bals, R. & German, C. C. Respir Res 25, 56 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38267944
Integration of implantable device therapy in patients with heart failure. A clinical consensus statement from the Heart Failure Association (HFA) and European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC). Mullens, W., Dauw, J., Gustafsson, F., Mebazaa, A., Steffel, J., Witte, K. K., Delgado, V., Linde, C., Vernooy, K., Anker, S. D., Chioncel, O., Milicic, D., Hasenfuss, G., Ponikowski, P., Stephan von Bardeleben, R., Koehler, F., Ruschitzka, F., Damman, K., Schwammenthal, E., Testani, J. M., Zannad, F., Bohm, M., Cowie, M. R., Dickstein, K., Jaarsma, T., Filippatos, G., Volterrani, M., Thum, T., Adamopoulos, S., Cohen-Solal, A., Moura, B., Rakisheva, A., Ristic, A., Bayes-Genis, A., Van Linthout, S., Tocchetti, C. G., Savarese, G., Skouri, H., Adamo, M., Amir, O., Yilmaz, M. B., Simpson, M., Tokmakova, M., Gonzalez, A., Piepoli, M., Seferovic, P., Metra, M., Coats, A. J. S. & Rosano, G. M. C. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38269474
Exercise training and high-sensitivity cardiac troponin-I in patients with heart failure with reduced ejection fraction. Riveland, E., Valborgland, T., Ushakova, A., Skadberg, O., Karlsen, T., Hole, T., Stoylen, A., Dalen, H., Videm, V., Koppen, E., Linke, A., Delagardelle, C., Van Craenenbroeck, E. M., Beckers, P., Prescott, E., Halle, M., Omland, T., Ellingsen, O., Larsen, A. I. & Group, S.-H. S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38268237
The prevalence and impact of sarcopenia in older cardiac patients undergoing inpatient cardiac rehabilitation - results from a prospective, observational cohort pre-study. Steinmetz, C., Krause, L., Sulejmanovic, S., Kaumkotter, S., Mengden, T., Grefe, C., Knoglinger, E., Reiss, N., Brixius, K., Bjarnason-Wehrens, B., Schmidt, T., von Haehling, S., Sadlonova, M., von Arnim, C. A. F. & Heinemann, S. BMC Geriatr 24, 94 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38267843
C-reactive protein, pharmacological treatments and diet: how to target your inflammatory burden. Bay, B., Arnold, N. & Waldeyer, C. Curr Opin Lipidol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38277208
Transcatheter management of pure native aortic valve regurgitation in patients with left ventricular assist device. Hinkov, H., Lee, C. B., Pitts, L., Lanmuller, P., Klein, C., Kukucka, M., Potapov, E., Kempfert, J., Falk, V., Dreger, H. & Unbehaun, A. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38273702
External Mechanical Stability Regulates Hematoma Vascularization in Bone Healing Rather than Endothelial YAP/TAZ Mechanotransduction. Mehl, J., Farahani, S. K., Brauer, E., Klaus-Bergmann, A., Thiele, T., Ellinghaus, A., Bartels-Klein, E., Koch, K., Schmidt-Bleek, K., Petersen, A., Gerhardt, H., Vogel, V. & Duda, G. N. Adv Sci (Weinh) 11, e2307050 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38273642
High-throughput methods for cardiac cellular electrophysiology studies: the road to personalized medicine. Seibertz, F. & Voigt, N. Am J Physiol Heart Circ Physiol 326, H938-H949 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38276947
Noise and mental health: evidence, mechanisms, and consequences. Hahad, O., Kuntic, M., Al-Kindi, S., Kuntic, I., Gilan, D., Petrowski, K., Daiber, A. & Munzel, T. J Expo Sci Environ Epidemiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38279032
Comparison of the clinical chemistry score to other biomarker algorithms for rapid rule-out of acute myocardial infarction and risk stratification in patients with suspected acute coronary syndrome. Yildirim, M., Salbach, C., Reich, C., Milles, B. R., Biener, M., Frey, N., Giannitsis, E. & Mueller-Hennessen, M. Int J Cardiol 400, 131815 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38278492
Risk factors for long-term invasive mechanical ventilation: a longitudinal study using German health claims data. Trudzinski, F. C., Michels-Zetsche, J. D., Neetz, B., Meis, J., Muller, M., Kempa, A., Neurohr, C., Schneider, A., Herth, F. J. F., Szecsenyi, J., Biehler, E., Fleischauer, T., Wensing, M., Britsch, S., Schubert-Haack, J., Grobe, T., Frerk, T. & group, P. R.-s. Respir Res 25, 60 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38281006
Surgical phase and instrument recognition: how to identify appropriate dataset splits. Kostiuchik, G., Sharan, L., Mayer, B., Wolf, I., Preim, B. & Engelhardt, S. Int J Comput Assist Radiol Surg 19, 699-711 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38285380
Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis. Ravindran, A., Holappa, L., Niskanen, H., Skovorodkin, I., Kaisto, S., Beter, M., Kiema, M., Selvarajan, I., Nurminen, V., Aavik, E., Aherrahrou, R., Pasonen-Seppanen, S., Fortino, V., Laakkonen, J. P., Yla-Herttuala, S., Vainio, S., Ord, T. & Kaikkonen, M. U. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38289873
LAA occlusion is effective and safe in very high-risk atrial fibrillation patients with prior stroke: results from the multicentre German LAARGE registry. Ansari, U., Brachmann, J., Lewalter, T., Zeymer, U., Sievert, H., Ledwoch, J., Geist, V., Hochadel, M., Schneider, S., Senges, J., Akin, I. & Fastner, C. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38294498
Beyond Weight Loss: the Emerging Role of Incretin-Based Treatments in Cardiometabolic HFpEF. Capone, F., Nambiar, N. & Schiattarella, G. G. Curr Opin Cardiol 39, 148-153 (2024). Beyond Weight Loss: the Emerging Role of Incretin-Based Treatments in Cardiometabolic HFpEF - PubMed (nih.gov)
ESR Bridges: CT builds bridges in coronary artery disease. Dewey, M., Henriques, J. P. S., Kirov, H. & Vliegenthart, R. Eur Radiol 34, 732-735 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291257
Cardiac remodelling in non-alcoholic fatty liver disease in the general population. Kostka, F., Ittermann, T., Gross, S., Laqua, F. C., Bulow, R., Volzke, H., Dorr, M., Kuhn, J. P., Markus, M. R. P. & Kromrey, M. L. Liver Int 44, 1032-1041 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38293745
The burden of frailty in heart failure: Prevalence, impacts on clinical outcomes and the role of heart failure medications. Lai, H. Y., Huang, S. T., Anker, S. D., von Haehling, S., Akishita, M., Arai, H., Chen, L. K. & Hsiao, F. Y. J Cachexia Sarcopenia Muscle (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291000
Right heart and left atrial strain to differentiate cardiac amyloidosis and Fabry disease. Mattig, I., Steudel, T., Klingel, K., Barzen, G., Frumkin, D., Spethmann, S., Romero Dorta, E., Stangl, K., Heidecker, B., Landmesser, U., Knebel, F., Canaan-Kuhl, S., Hahn, K. & Brand, A. Sci Rep 14, 2445 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291191
Practical Guide on Left Atrial Appendage Closure for the Non-implanting Physician. An International Consensus Paper. Potpara, T., Grygier, M., Haeusler, K. G., Nielsen-Kudsk, J. E., Berti, S., Genovesi, S., Marijon, E., Boveda, S., Tzikas, A., Boriani, G., Boersma, L. V. A., Tondo, C., De Potter, T., Lip, G. Y. H., Schnabel, R. B., Bauersachs, R., Senzolo, M., Basile, C., Bianchi, S., Osmancik, P., Schmidt, B., Landmesser, U., Doehner, W., Hindricks, G., Kovac, J. & Camm, A. J. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291925
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Sterenborg, R., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Asvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J., Cappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Coutinho de Almeida, R., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Echouffo Tcheugui, J. B., Ellervik, C., Eriksson, J. G., Ferrucci, L., Freudenberg, J., DiscovEHR, G. H. S., Regeneron Genetics, C., Fuchsberger, C., Gieger, C., Giulianini, F., Gogele, M., Graham, S. E., Grarup, N., Gunjaca, I., Hansen, T., Harding, B. N., Harris, S. E., Haunso, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, J. K., Karhus, L. L., Kiemeney, L., Kloppenburg, M., Kuhnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, A., Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Mollehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polasek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, M. S., Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sorensen, T. I. A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., van den Akker, E. B., van den Eynde, T., van der Klauw, M. M., van Heemst, D., Verroken, C., Visser, W. E., Vojinovic, D., Volzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zollner, S., Smit, J. W. A., Peeters, R. P., Kottgen, A., Teumer, A. & Medici, M. Nat Commun15, 888 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291025
