Development of miR-92a inhibitors for the treatment of cardiovascular disease


Funding ID

81X2200122

Project number

116

Institution
Johann Wolfgang Goethe-Universität Frankfurt am Main - Klinikum - Medizinische Klinik III
Project leader
Stefanie Dimmeler
Site
RheinMain
Short description

Based on own preliminary works that show that miR-92a inhibitors can improve cardiac function after infarction, the safety and optimisation studies necessary for an application in human … 

Based on own preliminary works that show that miR-92a inhibitors can improve cardiac function after infarction, the safety and optimisation studies necessary for an application in human beings are to be carried out in the context of the application. For this, the composition of the microRNA inhibitors is to be optimised and the necessary pharmacological and toxicological examinations are to be performed.

Project type
Translational Research Project
Funding
€ 2.458.429,63
Begin
01.02.2015
End
31.12.2019