Personalized Medicine: Molecular Stratification of DCM patients


Funding ID

81Z2400121

Project number

458

Institution
Universitätsmedizin Greifswald
Project leader
Stephan B. Felix
Site
Greifswald
Short description

The discovery of inflammatory processes involved in the development of cardiomyopathies has lead to the development of new therapies. The aim of this project is to use existing patient … 

The discovery of inflammatory processes involved in the development of cardiomyopathies has lead to the development of new therapies. The aim of this project is to use existing patient cohorts with dilated cardiomyopathy to investigate individual inflammatory risk profiles. Biomaterials will be investigated regarding new factors indicating an individual predisposition for developing the disease or factors influencing the progression of the disease. Generated hypotheses shall be further explored in experimental settings e.g. cell cultures or animal models. The major aim is to create new insights into the pathegenesis of DCM and to develop new diagnostic tools for dilated cardiomyopathy which may be also relevant for new therapeutic approaches.

Project type
Partner Site Projects
Keywords
dilated cardiomyopathy, risk profiles, biomarker, inflammatory processes, animal models, cell culture
Topic
Inflammatory heart diseases
Funding
€ 557.524,86
Begin
01.01.2012
End
31.12.2018