Publikationen 2013

Ubiquitin-Proteasome System and Hereditary Cardiomyopathies. Schlossarek, S., Frey, N. & Carrier, L. Journal of molecular and cellular cardiology, (2013).

Randomized Comparison of Ticagrelor Versus Prasugrel in Patients with Acute Coronary Syndrome and Planned Invasive Strategy-Design and Rationale of the Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment (Isar-React) 5 Trial. Schulz, S., Angiolillo, D. J., Antoniucci, D., Bernlochner, I., Hamm, C., Jaitner, J., Laugwitz, K. L., Mayer, K., von Merzljak, B., Morath, T., Neumann, F. J., Richardt, G., Ruf, J., Schomig, G., Schuhlen, H., Schunkert, H., Kastrati, A., Intracoronary, S. & Antithrombotic Regimen: Rapid Early Action for Coronary Treatment 5 Trial, I. Journal of cardiovascular translational research, (2013).

Periodontitis Is Associated with Endothelial Dysfunction in a General Population: A Cross-Sectional Study. Holtfreter, B., Empen, K., Glaser, S., Lorbeer, R., Volzke, H., Ewert, R., Kocher, T. & Dorr, M. PloS one 8, e84603, (2013).

Integrated Genomics and Metabolomics in Nephrology. Atzler, D., Schwedhelm, E. & Zeller, T. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2013).

Rotor Termination Is Critically Dependent on Kinetic Properties of I Kur Inhibitors in an in Silico Model of Chronic Atrial Fibrillation. Scholz, E. P., Carrillo-Bustamante, P., Fischer, F., Wilhelms, M., Zitron, E., Dossel, O., Katus, H. A. & Seemann, G. PloS one 8, e83179, (2013).

Argonaute2 Mediates Compensatory Expansion of the Pancreatic Beta Cell. Tattikota, S. G., Rathjen, T., McAnulty, S. J., Wessels, H. H., Akerman, I., van de Bunt, M., Hausser, J., Esguerra, J. L., Musahl, A., Pandey, A. K., You, X., Chen, W., Herrera, P. L., Johnson, P. R., O'Carroll, D., Eliasson, L., Zavolan, M., Gloyn, A. L., Ferrer, J., Shalom-Feuerstein, R. et al. Cell metabolism, (2013).

Fractalkine Promotes Platelet Activation and Vascular Dysfunction in Congestive Heart Failure. Hildemann, S. K., Schulz, C., Fraccarollo, D., Schopp, C., Flierl, U., Wissel, K., Pelisek, J., Massberg, S., Bauersachs, J. & Schafer, A. Thrombosis and haemostasis, (2013).

In Vitro Perfusion of Engineered Heart Tissue through Endothelialized Channels. Vollert, I., Seiffert, M., Bachmair, J., Sander, M., Eder, A., Conradi, L., Vogelsang, A., Schulze, T., Uebeler, J., Holnthoner, W., Redl, H., Reichenspurner, H., Hansen, A. & Eschenhagen, T. Tissue engineering. Part A, (2013).

Stroke Induced Sarcopenia: Muscle Wasting and Disability after Stroke. Scherbakov, N., von Haehling, S., Anker, S. D., Dirnagl, U. & Doehner, W. International journal of cardiology 170, 89-94, (2013).

Microrna-223 Antagonizes Angiogenesis by Targeting Beta1 Integrin and Preventing Growth Factor Signaling in Endothelial Cells. Shi, L., Fisslthaler, B., Zippel, N., Fromel, T., Hu, J., Elgheznawy, A., Heide, H., Popp, R. & Fleming, I. Circulation research 113, 1320-1330, (2013).

Functional Characterization of Zebrafish K18.1 (Tresk) Two-Pore-Domain K Channels. Rahm, A. K., Wiedmann, F., Gierten, J., Schmidt, C., Schweizer, P. A., Becker, R., Katus, H. A. & Thomas, D. Naunyn-Schmiedeberg's archives of pharmacology, (2013).

Transforming Growth Factor-Beta-Activated Kinase 1 Regulates Angiogenesis Via Amp-Activated Protein Kinase-Alpha1 and Redox Balance in Endothelial Cells. Zippel, N., Malik, R. A., Fromel, T., Popp, R., Bess, E., Strilic, B., Wettschureck, N., Fleming, I. & Fisslthaler, B. Arteriosclerosis, thrombosis, and vascular biology 33, 2792-2799, (2013).

Biomarkers and Perfusion – Training-Induced Changes after Stroke (Baptise): Protocol of an Observational Study Accompanying a Randomized Controlled Trial. Nave, A. H., Krober, J., Brunecker, P., Fiebach, J. B., List, J., Grittner, U., Endres, M., Meisel, A., Floel, A. & Ebinger, M. BMC Neurology 13, (2013).

Mybpc3 in Hypertrophic Cardiomyopathy: From Mutation Identification to Rna-Based Correction. Gawlik-Behrens, V., Mearini, G., Gedicke-Hornung, C., Richard, P. & Carrier, L. Pflügers Archiv - European Journal of Physiology, (2013).

Drug-Eluting Stents for Revascularization of Infrapopliteal Arteries: Updated Meta-Analysis of Randomized Trials. Fusaro, M., Cassese, S., Ndrepepa, G., Tepe, G., King, L., Ott, I., Nerad, M., Schunkert, H. & Kastrati, A. JACC. Cardiovascular interventions 6, 1284-1293, (2013).

[Ventricular Tachycardia : Treatment and Prognostic Significance]. Fichtner, S. & Kaab, S. Herzschrittmachertherapie & Elektrophysiologie 24, 217-222, (2013).

Diagnostic and Prognostic Value of Osteopontin in Patients with Acute Congestive Heart Failure. Behnes, M., Brueckmann, M., Lang, S., Espeter, F., Weiss, C., Neumaier, M., Ahmad-Nejad, P., Borggrefe, M. & Hoffmann, U. European journal of heart failure 15, 1390-1400, (2013).

Histone Deacetylase Signaling in Cardioprotection. Lehmann, L. H., Worst, B. C., Stanmore, D. A. & Backs, J. Cellular and molecular life sciences : CMLS, (2013).

Exercise Training in Patients with Chronic Heart Failure Promotes Restoration of High-Density Lipoprotein Functional Properties. Adams, V., Besler, C., Fischer, T., Riwanto, M., Noack, F., Hollriegel, R., Oberbach, A., Jehmlich, N., Volker, U., Winzer, E. B., Lenk, K., Hambrecht, R., Schuler, G., Linke, A., Landmesser, U. & Erbs, S. Circulation research 113, 1345-1355, (2013).

Impact of Coronary Anatomy and Stenting Technique on Long-Term Outcome after Drug-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Disease. Tiroch, K., Mehilli, J., Byrne, R. A., Schulz, S., Massberg, S., Laugwitz, K. L., Vorpahl, M., Seyfarth, M., Kastrati, A., for the Intracoronary, S. & Angiographic Results: Drug-Eluting Stents for Unprotected Coronary Left Main Lesions Study, I. JACC. Cardiovascular interventions, (2013).

Do Patients with Type 1 and Type 2 Diabetes Really Have an Impaired Endothelial Function? A Population-Based Propensity Score Matching Analysis. Empen, K., Lorbeer, R., Volzke, H., Reffelmann, T., Schipf, S., Nauck, M., Kerner, W., Wallaschofski, H., Felix, S. B. & Dorr, M. Cardiovascular diabetology 12, 174, (2013).

Association of Leptin and Insulin with Childhood Obesity and Retinal Vessel Diameters. Siegrist, M., Hanssen, H., Neidig, M., Fuchs, M., Lechner, F., Stetten, M., Blume, K., Lammel, C., Haller, B., Vogeser, M., Parhofer, K. G. & Halle, M. International journal of obesity, (2013).

Interleukin-23 Deficiency Leads to Impaired Wound Healing and Adverse Prognosis after Myocardial Infarction. Savvatis, K., Pappritz, K., Becher, P. M., Lindner, D., Zietsch, C., Volk, H. D., Westermann, D., Schultheiss, H. P. & Tschope, C. Circulation. Heart failure, (2013).

Release Kinetics of N-Terminal Pro-B-Type Natriuretic Peptide in a Clinical Model of Acute Myocardial Infarction. Liebetrau, C., Gaede, L., Dorr, O., Troidl, C., Voss, S., Hoffmann, J., Paszko, A., Weber, M., Rolf, A., Hamm, C., Nef, H. & Mollmann, H. Clinica chimica acta; international journal of clinical chemistry, (2013).

Coxsackie and Adenovirus Receptor (Car) Is a Modifier of Cardiac Conduction and Arrhythmia Vulnerability in the Setting of Myocardial Ischemia. Marsman, R. F., Bezzina, C. R., Freiberg, F., Verkerk, A. O., Adriaens, M. E., Podliesna, S., Chen, C., Purfurst, B., Spallek, B., Koopmann, T. T., Baczko, I., dos Remedios, C., George, A. L., Jr., Bishopric, N. H., Lodder, E. M., de Bakker, J. M. T., Fischer, R., Coronel, R., Wilde, A. A. M., Gotthardt, M. et al. Journal of the American College of Cardiology, (2013).

Quantitative and Qualitative Proteome Characteristics Extracted from in-Depth Integrated Genomics and Proteomics Analysis. Low, T., Van Heesch, S., Van den Toorn, H., Giansanti, P., Cristobal, A., Toonen, P., Schafer, S., Hubner, N., Van Breukelen, B., Mohammed, S., Cuppen, E., Heck, A. J. R. & Guryev, V. Cell Reports, (2013).

Evaluation of the Prevalence and Prospective Clinical Impact of the Jak2 V617f Mutation in Coronary Patients. Muendlein, A., Gasser, K., Kinz, E., Stark, N., Leiherer, A., Rein, P., Saely, C. H., Grallert, H., Peters, A., Drexel, H. & Lang, A. H. American journal of hematology, (2013).

Incidence and Predictors of Restenosis after Coronary Stenting in 10 004 Patients with Surveillance Angiography. Cassese, S., Byrne, R. A., Tada, T., Pinieck, S., Joner, M., Ibrahim, T., King, L. A., Fusaro, M., Laugwitz, K. L. & Kastrati, A. Heart, (2013).

Beta-Catenin-Dependent Pathway Activation by Both Promiscuous "Canonical" Wnt3a-, and Specific "Noncanonical" Wnt4- and Wnt5a-Fzd Receptor Combinations with Strong Differences in Lrp5 and Lrp6 Dependency. Ring, L., Neth, P., Weber, C., Steffens, S. & Faussner, A. Cellular signalling, (2013).

Activation of Calcium/Calmodulin-Dependent Protein Kinase Ii in Obesity Mediates Suppression of Hepatic Insulin Signaling. Ozcan, L., de Souza, J. C., Harari, A. A., Backs, J., Olson, E. N. & Tabas, I. Cell metabolism 18, (2013).

Platelet-Derived Pf4 Reduces Neutrophil Apoptosis Following Arterial Occlusion. Hartwig, H., Drechsler, M., Lievens, D., Kramp, B., von Hundelshausen, P., Lutgens, E., Weber, C., Doring, Y. & Soehnlein, O. Thrombosis and haemostasis 111, (2013).

Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease: A Genome-Wide Analysis of Common Variants. Dichgans, M., Malik, R., Konig, I. R., Rosand, J., Clarke, R., Gretarsdottir, S., Thorleifsson, G., Mitchell, B. D., Assimes, T. L., Levi, C., Odonnell, C. J., Fornage, M., Thorsteinsdottir, U., Psaty, B. M., Hengstenberg, C., Seshadri, S., Erdmann, J., Bis, J. C., Peters, A., Boncoraglio, G. B. et al. Stroke; a journal of cerebral circulation, (2013).

Sex- and Estrogen-Dependent Regulation of a Mirna Network in the Healthy and Hypertrophied Heart. Queiros, A. M., Eschen, C., Fliegner, D., Kararigas, G., Dworatzek, E., Westphal, C., Sanchez Ruderisch, H. & Regitz-Zagrosek, V. International journal of cardiology 169, 331-338, (2013).

Functional Microrna Library Screening Identifies the Hypoxamir Mir-24 as a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization. Fiedler, J., Stohr, A., Gupta, S. K., Hartmann, D., Holzmann, A., Just, A., Hansen, A., Hilfiker-Kleiner, D., Eschenhagen, T. & Thum, T. Antioxidants & redox signaling, (2013).

Not All Beta-Blockers Are Equal in the Management of Long Qt Syndrome Types 1 and 2: Higher Recurrence of Events under Metoprolol. Chockalingam, P., Crotti, L., Girardengo, G., Johnson, J. N., Harris, K. M., van der Heijden, J. F., Hauer, R. N., Beckmann, B. M., Spazzolini, C., Rordorf, R., Rydberg, A., Clur, S. A., Fischer, M., van den Heuvel, F., Kaab, S., Blom, N. A., Ackerman, M. J., Schwartz, P. J. & Wilde, A. A. Journal of the American College of Cardiology 60, 2092-2099, (2012).

Sick Sinus Syndrome in Hcn1-Deficient Mice. Fenske, S., Krause, S. C., Hassan, S. I., Becirovic, E., Auer, F., Bernard, R., Kupatt, C., Lange, P., Ziegler, T., Wotjak, C. T., Zhang, H., Hammelmann, V., Paparizos, C., Biel, M. & Wahl-Schott, C. A. Circulation, (2013).

Dysfunctional Nitric Oxide Signalling Increases Risk of Myocardial Infarction. Erdmann, J., Stark, K., Esslinger, U. B., Rumpf, P. M., Koesling, D., de Wit, C., Kaiser, F. J., Braunholz, D., Medack, A., Fischer, M., Zimmermann, M. E., Tennstedt, S., Graf, E., Eck, S., Aherrahrou, Z., Nahrstaedt, J., Willenborg, C., Bruse, P., Braenne, I., Nothen, M. M. et al. Nature, (2013).

Evidence for a Regulatory Role of Cullin-Ring E3 Ubiquitin Ligase 7 in Insulin Signaling. Scheufele, F., Wolf, B., Kruse, M., Hartmann, T., Lempart, J., Muhlich, S., Pfeiffer, A. F., Field, L. J., Charron, M. J., Pan, Z. Q., Engelhardt, S. & Sarikas, A. Cellular signalling, (2013).

Biomechanical Regulation of in Vitro Cardiogenesis for Tissue-Engineered Heart Repair. Zimmermann, W. H. Stem cell research 4, (2013).

Chronic At1-Receptor Blockade Improves Cardinal Symptoms of Metabolic Syndrome in Diet-Induced Rat Obesity. Muller-Fielitz, H., Hubel, N., Mildner, M., Vogt, F. M., Barkhausen, J. & Raasch, W. British journal of pharmacology, (2013).

The Role of Extracellular Rna in Atherosclerotic Plaque Formation in Mice. Simsekyilmaz, S., Cabrera-Fuentes, H. A., Meiler, S., Kostin, S., Baumer, Y., Liehn, E. A., Weber, C., Boisvert, W. A., Preissner, K. T. & Zernecke, A. Circulation, (2013).

Ionizing Radiation Regulates Cardiac Ca Handling Via Increased Ros and Activated Camkii. Sag, C. M., Wolff, H. A., Neumann, K., Opiela, M. K., Zhang, J., Steuer, F., Sowa, T., Gupta, S., Schirmer, M., Hunlich, M., Rave-Frank, M., Hess, C. F., Anderson, M. E., Shah, A. M., Christiansen, H. & Maier, L. S. Basic research in cardiology 108, 385, (2013).

Pluripotent Stem Cell Models of Human Heart Disease. Moretti, A., Laugwitz, K. L., Dorn, T., Sinnecker, D. & Mummery, C. Cold Spring Harbor perspectives in medicine 3, (2013).

[Ventricular Tachycardia : Treatment and Prognostic Significance.]. Fichtner, S. & Kaab, S. Herzschrittmachertherapie & Elektrophysiologie, (2013).

Drug-Eluting Stent Trials: Too Much Non-Inferiority, Too Little Progress? Byrne, R. A. & Kastrati, A. Lancet, (2013).

Nfat and Mir-25 Cooperate to Reactivate the Transcription Factor Hand2 in Heart Failure. Dirkx, E., Gladka, M. M., Philippen, L. E., Armand, A. S., Kinet, V., Leptidis, S., El Azzouzi, H., Salic, K., Bourajjaj, M., da Silva, G. J., Olieslagers, S., van der Nagel, R., de Weger, R., Bitsch, N., Kisters, N., Seyen, S., Morikawa, Y., Chanoine, C., Heymans, S., Volders, P. G. et al. Nature cell biology, (2013).

Lxr Agonism Improves Tnf-Α-Induced Endothelial Dysfunction in the Absence of Its Cholesterol-Modulating Effects. Spillmann, F., Van Linthout, S., Miteva, K., Lorenz, M., Stangl, V., Schultheiss, H. P. & Tschope, C. Atherosclerosis, (2013).

In-Vitro Perfusion of Engineered Heart Tissue through Endothelialized Channels. Vollert, I., Seiffert, M., Bachmair, J., Sander, M., Eder, A., Conradi, L., Vogelsang, A., Schulze, T., Uebeler, J., Holnthoner, W., Redl, H., Reichenspurner, H., Hansen, A. & Eschenhagen, T. Tissue engineering. Part A, (2013).

Myocardial Ct Perfusion Imaging in a Large Animal Model : Comparison of Dynamic Versus Single-Phase Acquisitions. Schwarz, F., Hinkel, R., Baloch, E., Marcus, R., Hildebrandt, K., Sandner, T. A., Kupatt, C., Hoffmann, V., Wintersperger, B. J., Reiser, M. F., Theisen, D., Nikolaou, K. & Bamberg, F. JACC: Cardiovascular Imaging, (2013).

Determination of DNA Methylation Patterns in Cardiac Tissue from Hypoplastic Left Heart Syndrome. Hoff, K., Ammerpohl, O., Kolarova, J., Arndt, A. K., Pfeffer, K., Toka, O., Siebert, R. & Kramer, H. H. The Thoracic and cardiovascular surgeon, (2013).

Phosphodiesterase-2 Is up-Regulated in Human Failing Hearts and Blunts Beta-Adrenergic Responses in Cardiomyocytes. Mehel, H., Emons, J., Vettel, C., Wittkopper, K., Seppelt, D., Dewenter, M., Lutz, S., Sossalla, S., Maier, L. S., Lechene, P., Leroy, J., Lefebvre, F., Varin, A., Eschenhagen, T., Nattel, S., Dobrev, D., Zimmermann, W. H., Nikolaev, V. O., Vandecasteele, G., Fischmeister, R. et al. Journal of the American College of Cardiology 62, 1596-1606, (2013).

Dopamine and Lipophilic Derivates Protect Cardiomyocytes against Cold Preservation Injury. Vettel, C., Hottenrott, M. C., Spindler, R., Benck, U., Schnuelle, P., Tsagogiorgas, C., Kraemer, B. K., Hoeger, S., El-Armouche, A., Wieland, T. & Yard, B. A. The Journal of pharmacology and experimental therapeutics, (2013).

Coinciding Functions for Mir-145 in Vascular Smooth Muscle and Cardiac Fibroblasts. Engelhardt, S. & Leierseder, S. Journal of molecular and cellular cardiology, (2013).

Can Speckle-Tracking Imaging Improve the Reliability of Echocardiographic Parameters for Outcome Evaluation in Clinical Trials? Tschope, C. & Kasner, M. European heart journal, (2013).

Is There a Protocol for Using the Sprec? Nussbeck, S., Benson, E., Betsou, F., Guadagni, F., Lehmann, S. & Umbach, S. Biopreservation and Biobanking 11, 260-266, (2013).

Stroke Induced Sarcopenia: Muscle Wasting and Disability after Stroke. Scherbakov, N., Anker, S., Dirnagl, U. & Doehner, W. International journal of cardiology, (2013).

Real-Time Flow Mri of the Aorta at a Resolution of 40 Msec. Joseph, A., Kowallick, J. T., Merboldt, K. D., Voit, D., Schaetz, S., Zhang, S., Sohns, J. M., Lotz, J. & Frahm, J. Journal of magnetic resonance imaging : JMRI, (2013).

Current Role and Future Potential of Magnetic Resonance Cholangiopancreatography with an Emphasis on Incidental Findings. Sohns, J. M., Staab, W., Dabir, D., Spiro, J. E., Bergau, L., Schwarz, A. & Sohns, C. Clinical imaging, (2013).

Ccr6 Selectively Promotes Monocyte Mediated Inflammation and Atherogenesis in Mice. Manthey, H. D., Cochain, C., Barnsteiner, S., Karshovska, E., Pelisek, J., Koch, M., Chaudhari, S. M., Busch, M., Eckstein, H. H., Weber, C., Koenen, R. R. & Zernecke, A. Thrombosis and haemostasis 110, (2013).

Pet/Ct and Mr Imaging in a Murine Model of Progressiveatherosclerosis Using 64cu-Labeled Glycoprotein Vi-Fc. Bigalke, B., Phinikaridou, A., Andia, M. E., Cooper, M. S., Schuster, A., Schonberger, T., Griessinger, C. M., Wurster, T., Onthank, D., Ungerer, M., Gawaz, M., Nagel, E. & Botnar, R. M. Circulation. Cardiovascular imaging, (2013).

Novel Role of Mechanosensitive at Receptors in Myogenic Vasoconstriction. Blodow, S., Schneider, H., Storch, U., Wizemann, R., Forst, A. L., Gudermann, T. & Mederos, Y. S. M. Pflugers Archiv : European journal of physiology, (2013).

Incidence and Impact on Prognosis of Bleeding During Percutaneous Coronary Interventions in Patients with Chronic Kidney Disease. Ndrepepa, G., Neumann, F. J., Cassese, S., Fusaro, M., Ott, I., Schulz, S., Hoppmann, P., Richardt, G., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Clinical research in cardiology : official journal of the German Cardiac Society, (2013).

Nonlinear System Identification Employing Automatic Differentiation. Schumann-Bischoff, J., Luther, S. & Parlitz, U. Commun Nonlinear Sci Numer Simul 18, 2733–2742, (2013).

Embryonic Heart Progenitors and Cardiogenesis. Brade, T., Pane, L. S., Moretti, A., Chien, K. R. & Laugwitz, K. L. Cold Spring Harbor perspectives in medicine 3, (2013).

Rhythm Control of Atrial Fibrillation in Heart Failure. Heijman, J., Voigt, N., Abu-Taha, I. H. & Dobrev, D. Heart failure clinics 9, 407-415, (2013).

Transforming Growth Factor-Beta-Activated Kinase 1 Regulates Angiogenesis Via Amp-Activated Protein Kinase-Alpha1 and Redox Balance in Endothelial Cells. Zippel, N., Malik, R. A., Fromel, T., Popp, R., Bess, E., Strilic, B., Wettschureck, N., Fleming, I. & Fisslthaler, B. Arteriosclerosis, thrombosis, and vascular biology, (2013).

Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia. Stitziel, N. O., Fouchier, S. W., Sjouke, B., Peloso, G. M., Moscoso, A. M., Auer, P. L., Goel, A., Gigante, B., Barnes, T. A., Melander, O., Orho-Melander, M., Duga, S., Sivapalaratnam, S., Nikpay, M., Martinelli, N., Girelli, D., Jackson, R. D., Kooperberg, C., Lange, L. A., Ardissino, D. et al. Arteriosclerosis, thrombosis, and vascular biology, (2013).

Mir-223 Is Dispensable for Platelet Production and Function in Mice. Leierseder, S., Petzold, T., Zhang, L., Loyer, X., Massberg, S. & Engelhardt, S. Thrombosis and haemostasis 110, (2013).

Endothelial Jam-a Guides Monocytes into Flow-Dependent Predilection Sites of Atherosclerosis. Schmitt, M. M., Megens, R. T., Zernecke, A., Bidzhekov, K., van den Akker, N. M., Rademakers, T., van Zandvoort, M. A., Hackeng, T. M., Koenen, R. R. & Weber, C. Circulation, (2013).

Homoarginine Levels Are Regulated by L-Arginine:Glycine Amidinotransferase and Affect Stroke Outcome: Results from Human and Murine Studies. Choe, C. U., Atzler, D., Wild, P. S., Carter, A. M., Boger, R. H., Ojeda, F., Simova, O., Stockebrand, M., Lackner, K., Nabuurs, C., Marescau, B., Streichert, T., Muller, C., Luneburg, N., De Deyn, P. P., Benndorf, R. A., Baldus, S., Gerloff, C., Blankenberg, S., Heerschap, A. et al. Circulation 128, 1451-1461, (2013).

Mir-1/133a Clusters Cooperatively Specify the Cardiomyogenic Lineage by Adjustment of Myocardin Levels During Embryonic Heart Development. Wystub, K., Besser, J., Bachmann, A., Boettger, T. & Braun, T. PLoS genetics 9, e1003793, (2013).

Transcriptome and Genome Sequencing Uncovers Functional Variation in Humans. Lappalainen, T., Sammeth, M., Friedlander, M. R., t Hoen, P. A., Monlong, J., Rivas, M. A., Gonzalez-Porta, M., Kurbatova, N., Griebel, T., Ferreira, P. G., Barann, M., Wieland, T., Greger, L., van Iterson, M., Almlof, J., Ribeca, P., Pulyakhina, I., Esser, D., Giger, T., Tikhonov, A. et al. Nature, (2013).

Patching the Heart: Cardiac Repair from within and Outside. Ye, L., Zimmermann, W. H., Garry, D. J. & Zhang, J. Circulation research 113, 922-932, (2013).

Rhodamine-Loaded Icam-Targeted Microbubbles for Dual-Modality Imaging under Controlled Shear Stresses. Wu, Z., Curaj, A., Fokong, S., Liehn, E. A., Weber, C., Lammers, T., Kiessling, F. & van Zandvoort, M. Circulation. Cardiovascular imaging, (2013).

Incidence and Prognostic Value of Bleeding after Percutaneous Coronary Intervention in Patients Older Than 75 Years of Age. Ndrepepa, G., Neumann, F. J., Schulz, S., Fusaro, M., Cassese, S., Byrne, R. A., Richardt, G., Laugwitz, K. L. & Kastrati, A. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, (2013).

Real-Time Cardiovascular Magnetic Resonance at 1.5 T Using Balanced Ssfp and 40 Ms Resolution. Voit, D., Zhang, S., Unterberg-Buchwald, C., Sohns, J. M., Lotz, J. & Frahm, J. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 15, 79, (2013).

High-Pitch Coronary Ct Angiography in Dual-Source Ct During Free Breathing Vs. Breath Holding in Patients with Low Heart Rates. Bischoff, B., Meinel, F. G., Del Prete, A., Reiser, M. F. & Becker, H. C. European journal of radiology, (2013).  

Troponin: More Lessons to Learn. Liebetrau, C., Nef, H. M. & Hamm, C. W. European heart journal, (2013).

Load Dependency of Right Ventricular Performance Is a Major Factor to Be Considered in Decision Making before Ventricular Assist Device Implantation. Dandel, M., Potapov, E., Krabatsch, T., Stepanenko, A., Low, A., Vierecke, J., Knosalla, C. & Hetzer, R. Circulation 128, S14-23, (2013).

Systematic Identification of Trans Eqtls as Putative Drivers of Known Disease Associations. Westra, H. J., Peters, M. J., Esko, T., Yaghootkar, H., Schurmann, C., Kettunen, J., Christiansen, M. W., Fairfax, B. P., Schramm, K., Powell, J. E., Zhernakova, A., Zhernakova, D. V., Veldink, J. H., Van den Berg, L. H., Karjalainen, J., Withoff, S., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., t Hoen, P. A. et al. Nature genetics, (2013).

Preprocedural High-Sensitive Troponin Predicts Survival after Transcatheter Aortic Valve Implantation (Tavi). Frank, D., Stark, S., Lutz, M., Weissbrodt, A., Freitag-Wolf, S., Petzina, R., Rosenberg, M., Lutter, G. & Frey, N. International journal of cardiology, (2013).

Dyrk2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of Gsk-3beta on Eif2bepsilon. Weiss, C. S., Ochs, M. M., Hagenmueller, M., Streit, M. R., Malekar, P., Riffel, J. H., Buss, S. J., Weiss, K. H., Sadoshima, J., Katus, H. A. & Hardt, S. E. PloS one 8, e70848, (2013).

Intravenous Beta Blockers in Primary Pci: New Hope for an Old Therapy. Ndrepepa, G. & Kastrati, A. Circulation, (2013).

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Bleeding after Percutaneous Coronary Intervention in Women and Men Matched for Age, Body Mass Index, and Type of Antithrombotic Therapy. Ndrepepa, G., Schulz, S., Neumann, F. J., Byrne, R. A., Hoppmann, P., Cassese, S., Ott, I., Fusaro, M., Ibrahim, T., Tada, T., Richardt, G., Laugwitz, K. L., Schunkert, H. & Kastrati, A. American heart journal 166, 534-540, (2013).

The Big Picture: Evidence Base and Current Trials in Cardiac Ct. Hetterich, H., Nikolaou, K., Reiser, M. & Bamberg, F. Current Radiology Reports, (2013).

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Cad Detection in Patients with Intermediate-High Pre-Test Probability: Low-Dose Ct Delayed Enhancement Detects Ischemic Myocardial Scar with Moderate Accuracy but Does Not Improve Performance of a Stress-Rest Ct Perfusion Protocol. Bettencourt, N., Ferreira, N. D., Leite, D., Carvalho, M., Ferreira, W. D., Schuster, A., Chiribiri, A., Leite-Moreira, A., Silva-Cardoso, J., Nagel, E. & Gama, V. JACC. Cardiovascular imaging, (2013).

Functional Expression of the Transient Receptor Potential Channel Trpa1, a Sensor for Toxic Lung Inhalants, in Pulmonary Epithelial Cells. Robert Heinrich Buch, T., Anna Maria Schafer, E., Demmel, M. T., Boekhoff, I., Thiermann, H., Gudermann, T., Steinritz, D. & Schmidt, A. Chemico-biological interactions, (2013).

Heart Failure Gene Therapy: The Path to Clinical Practice. Pleger, S. T., Brinks, H., Ritterhoff, J., Raake, P., Koch, W. J., Katus, H. A. & Most, P. Circulation research 113, 792-809, (2013).

Ca2+/Calmodulin-Dependent Protein Kinase Ii and Protein Kinase a Differentially Regulate Sarcoplasmic Reticulum Ca2+ Leak in Human Cardiac Pathology. Fischer, T. H., Herting, J., Tirilomis, T., Renner, A., Neef, S., Toischer, K., Ellenberger, D., Forster, A., Schmitto, J. D., Gummert, J., Schondube, F. A., Hasenfuss, G., Maier, L. S. & Sossalla, S. Circulation 128, 970-981, (2013).

A Multi-Ethnic Meta-Analysis of Genome-Wide Association Studies in over 100,000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association between Circulating Fibrinogen and Cardiovascular Disease. Sabater-Lleal, M., Huang, J., Chasman, D. I., Naitza, S., Dehghan, A., Johnson, A. D., Teumer, A., Reiner, A. P., Folkersen, L., Basu, S., Rudnicka, A. R., Trompet, S., Malarstig, A., Baumert, J., Bis, J. C., Guo, X., Hottenga, J. J., Shin, S. Y., Lopez, L. M., Lahti, J. et al. Circulation, (2013).

Modeling Myocardial Growth and Hypertrophy in Engineered Heart Muscle. Tiburcy, M. & Zimmermann, W. H. Trends in cardiovascular medicine, (2013).

Pleiotropic Effects of Antiarrhythmic Agents: Dronedarone in the Treatment of Atrial Fibrillation. Heijman, J., Heusch, G. & Dobrev, D. Clinical Medicine Insights. Cardiology 7, 127-140, (2013).

Exchange of Extracellular Domains of Ccr1 and Ccr5 Reveals Confined Functions in Ccl5-Mediated Cell Recruitment. Kramp, B. K., Megens, R. T., Sarabi, A., Winkler, S., Projahn, D., Weber, C., Koenen, R. R. & von Hundelshausen, P. Thrombosis and haemostasis 110, (2013).

Sphingosine Kinase 2 (Sphk2) Regulates Platelet Biogenesis by Providing Intracellular Sphingosine 1-Phosphate (S1p). Zhang, L., Urtz, N., Gaertner, F., Legate, K. R., Petzold, T., Lorenz, M., Mazharian, A., Watson, S. P. & Massberg, S. Blood 122, 791-802, (2013).

Genome Sequencing Reveals Loci under Artificial Selection That Underlie Disease Phenotypes in the Laboratory Rat. Atanur, S. S., Diaz, A. G., Maratou, K., Sarkis, A., Rotival, M., Game, L., Tschannen, M. R., Kaisaki, P. J., Otto, G. W., Ma, M. C., Keane, T. M., Hummel, O., Saar, K., Chen, W., Guryev, V., Gopalakrishnan, K., Garrett, M. R., Joe, B., Citterio, L., Bianchi, G. et al. Cell 154, 691-703, (2013).

Circulating Angiopoietin-2, Its Soluble Receptor Tie-2, and Mortality in the General Population. Lorbeer, R., Baumeister, S. E., Dorr, M., Nauck, M., Grotevendt, A., Volzke, H., Vasan, R. S., Wallaschofski, H. & Lieb, W. European journal of heart failure, (2013).

Functional Iron Deficiency and Diastolic Function in Heart Failure with Preserved Ejection Fraction. Kasner, M., Aleksandrov, A. S., Westermann, D., Lassner, D., Gross, M., Von Haehling, S., Anker, S., Schultheiss, H. P. & Tschope, C. International journal of cardiology, (2013).

Inhibition of Microrna-92a Protects against Ischemia-Reperfusion Injury in a Large Animal Model. Hinkel, R., Penzkofer, D., Zuhlke, S., Fischer, A., Husada, W., Xu, Q. F., Baloch, E., van Rooij, E., Zeiher, A. M., Kupatt, C. & Dimmeler, S. Circulation, (2013).

Contractile Abnormalities and Altered Drug Response in Engineered Heart Tissue from Mybpc3-Targeted Knock-in Mice. Stohr, A., Friedrich, F. W., Flenner, F., Geertz, B., Eder, A., Schaaf, S., Hirt, M. N., Uebeler, J., Schlossarek, S., Carrier, L., Hansen, A. & Eschenhagen, T. Journal of molecular and cellular cardiology, (2013).

Nsc23766, a Widely Used Inhibitor of Rac1 Activation, Additionally Acts as a Competitive Antagonist at Muscarinic Acetylcholine Receptors. Levay, M., Krobert, K. A., Wittig, K., Vogt, N., Bermudez, M., Wolber, G., Dobrev, D., Levy, F. O. & Wieland, T. The Journal of pharmacology and experimental therapeutics, (2013).

Homoarginine - an Independent Marker of Mortality in Heart Failure. Atzler, D., Rosenberg, M., Anderssohn, M., Choe, C. U., Lutz, M., Zugck, C., Boger, R. H., Frey, N. & Schwedhelm, E. International journal of cardiology, (2013).

Prognostic Value of Access and Non-Access Sites Bleeding after Percutaneous Coronary Intervention. Ndrepepa, G., Neumann, F. J., Richardt, G., Schulz, S., Tolg, R., Stoyanov, K. M., Gick, M., Ibrahim, T., Fiedler, K. A., Berger, P. B., Laugwitz, K. L. & Kastrati, A. Circulation. Cardiovascular interventions, (2013).

Provocation of an Autoimmune Response to Cardiac Voltage-Gated Sodium Channel Nav1.5 Induces Cardiac Conduction Defects in Rats. Korkmaz, S., Zitron, E., Bangert, A., Seyler, C., Li, S., Hegedus, P., Scherer, D., Li, J., Fink, T., Schweizer, P. A., Giannitsis, E., Karck, M., Szabo, G., Katus, H. A. & Kaya, Z. Journal of the American College of Cardiology 62, 340-349, (2013).

Polymer Coatings on Drug-Eluting Stents: Samson's Hair and Achilles' Heel? Basalus, M. W., Joner, M., von Birgelen, C. & Byrne, R. A. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 9, 302-305, (2013).

Common Variants at Scn5a-Scn10a and Hey2 Are Associated with Brugada Syndrome, a Rare Disease with High Risk of Sudden Cardiac Death. Bezzina, C. R., Barc, J., Mizusawa, Y., Remme, C. A., Gourraud, J. B., Simonet, F., Verkerk, A. O., Schwartz, P. J., Crotti, L., Dagradi, F., Guicheney, P., Fressart, V., Leenhardt, A., Antzelevitch, C., Bartkowiak, S., Schulze-Bahr, E., Zumhagen, S., Behr, E. R., Bastiaenen, R., Tfelt-Hansen, J. et al. Nature genetics, (2013).

Camkii and Pka Differentially Regulate Sr Ca2+-Leak in Human Cardiac Pathology. Fischer, T., Herting, J., Tirilomis, T., Renner, A., Neef, S., Toischer, K., Ellenberger, D., Forster, A., Schmitto, J., Gummert, J., Schondube, F., Hasenfuss, G., Maier, L. & Sossalla, S. Circulation, (2013).

Compartmentalized Protective and Detrimental Effects of Endogenous Migration-Inhibitory Factor Mediated by Cxcr2 in a Mouse Model of Myocardial Ischemia/Reperfusion. Liehn, E. A., Kanzler, I., Konschalla, S., Kroh, A., Simsekyilmaz, S., Sonmez, T. T., Bucala, R., Bernhagen, J. & Weber, C. Arteriosclerosis, thrombosis, and vascular biology, (2013).

The Association of Smoking Status with Healthcare Utilisation, Productivity Loss and Resulting Costs: Results from the Population-Based Kora F4 Study. Wacker, M., Holle, R., Heinrich, J., Ladwig, K. H., Peters, A., Leidl, R. & Menn, P. BMC health services research 13, 278, (2013).

Multivariate Mirna Signatures as Biomarkers for Non-Ischaemic Systolic Heart Failure. Vogel, B., Keller, A., Frese, K. S., Leidinger, P., Sedaghat-Hamedani, F., Kayvanpour, E., Kloos, W., Backe, C., Thanaraj, A., Brefort, T., Beier, M., Hardt, S., Meese, E., Katus, H. A. & Meder, B. European heart journal, (2013).

A Genome-Wide Association Study Identifies 6p21 as Novel Risk Locus for Dilated Cardiomyopathy. Meder, B., Ruhle, F., Weis, T., Homuth, G., Keller, A., Franke, J., Peil, B., Lorenzo Bermejo, J., Frese, K., Huge, A., Witten, A., Vogel, B., Haas, J., Volker, U., Ernst, F., Teumer, A., Ehlermann, P., Zugck, C., Friedrichs, F., Kroemer, H. et al. European heart journal, (2013).

Enhanced Ca2+ Influx through Cardiac L-Type Ca2+ Channels Maintains the Systolic Ca2+ Transient in Early Cardiac Atrophy Induced by Mechanical Unloading. Schwoerer, A. P., Neef, S., Broichhausen, I., Jacubeit, J., Tiburcy, M., Wagner, M., Biermann, D., Didie, M., Vettel, C., Maier, L. S., Zimmermann, W. H., Carrier, L., Eschenhagen, T., Volk, T., El-Armouche, A. & Ehmke, H. Pflugers Archiv : European journal of physiology, (2013).

Elac2 Mutations Cause a Mitochondrial Rna Processing Defect Associated with Hypertrophic Cardiomyopathy. Haack, T. B., Kopajtich, R., Freisinger, P., Wieland, T., Rorbach, J., Nicholls, T. J., Baruffini, E., Walther, A., Danhauser, K., Zimmermann, F. A., Husain, R. A., Schum, J., Mundy, H., Ferrero, I., Strom, T. M., Meitinger, T., Taylor, R. W., Minczuk, M., Mayr, J. A. & Prokisch, H. American journal of human genetics, (2013).

Repair of Mybpc3 Mrna by 5'-Trans-Splicing in a Mouse Model of Hypertrophic Cardiomyopathy. Mearini, G., Stimpel, D., Kramer, E., Geertz, B., Braren, I., Gedicke-Hornung, C., Precigout, G., Muller, O. J., Katus, H. A., Eschenhagen, T., Voit, T., Garcia, L., Lorain, S. & Carrier, L. Molecular therapy. Nucleic acids 2, e102, (2013).

Angiopoietin 2 Mediates Microvascular and Hemodynamic Alterations in Sepsis. Ziegler, T., Horstkotte, J., Schwab, C., Pfetsch, V., Weinmann, K., Dietzel, S., Rohwedder, I., Hinkel, R., Gross, L., Lee, S., Hu, J., Soehnlein, O., Franz, W. M., Sperandio, M., Pohl, U., Thomas, M., Weber, C., Augustin, H. G., Fassler, R., Deutsch, U. et al. The Journal of clinical investigation, (2013).

Pleiotropic Actions of Amiodarone: Still Puzzling after Half a Century. Heijman, J. & Dobrev, D. Naunyn-Schmiedeberg's archives of pharmacology 386, 571-574, (2013).

Assessment of Cardiac Inflammation and Remodeling During the Development of Streptozotocin-Induced Diabetic Cardiomyopathy in Vivo: A Time Course Analysis. Becher, P. M., Lindner, D., Frohlich, M., Savvatis, K., Westermann, D. & Tschope, C. International journal of molecular medicine 32, 158-164, (2013).

Immunological Properties of Extraembryonic Human Mesenchymal Stromal Cells Derived from Gestational Tissue. Stubbendorff, M., Deuse, T., Hua, X., Phan, T. T., Bieback, K., Atkinson, K., Eiermann, T. H., Velden, J., Schroder, C., Reichenspurner, H., Robbins, R. C., Volk, H. D. & Schrepfer, S. Stem cells and development, (2013).

Phosphodiesterase-2 Is Upregulated in Human Failing Hearts and Blunts Β-Adrenergic Responses in Cardiomyocytes. Mehel, H., Emons, J., Vettel, C., Wittkopper, K., Seppelt, D., Dewenter, M., Lutz, S., Sossalla, S., Maier, L. S., Lechene, P., Leroy, J., Lefebvre, F., Varin, A., Eschenhagen, T., Nattel, S., Dobrev, D., Zimmermann, W., Nikolaev, V., Vandecasteele, G., Fischmeister, R. et al. JACC (2013).

Fasting Versus Post-Challenge Triglycerides and Pre-Existing Cavitating Lacunes: A Berlin “Cream & Sugar” Substudy. Leonards, C. O., Wang, L., Fiebach, J. B., Endres, M. & Ebinger, M. Front. Neurol. 4, (2013).

[Percutaneous Mitral Valve Repair with the Mitraclip(R) Procedure : Patient Eligibility Criteria.]. Braun, D., Orban, M., Tittus, J., Nabauer, M., Hagl, C., Massberg, S. & Hausleiter, J. Herz, (2013).

A Novel Apj Signaling Cascade That Regulates Cardiovascular Development. Loot, A. E. & Fleming, I. Circulation research 113, 4-6, (2013).

Thrombocytosis as a Response to High Interleukin-6 Levels in Cgmp-Dependent Protein Kinase I Mutant Mice. Zhang, L., Lukowski, R., Gaertner, F., Lorenz, M., Legate, K. R., Domes, K., Angermeier, E., Hofmann, F. & Massberg, S. Arteriosclerosis, thrombosis, and vascular biology, (2013).

Preservation of Left Ventricular Function and Morphology in Volume-Loaded Vs. Unloaded Heterotopic Heart Transplants. Didie, M., Biermann, D., Buchert, R., Hess, A., Wittkopper, K., Cristalla, P., Doker, S., Jebran, F., Schondube, F. A., Reichenspurner, H., El-Armouche, A. & Zimmermann, W. H. American journal of physiology. Heart and circulatory physiology, (2013).

Fine Mapping of the 1p36 Deletion Syndrome Identifies Mutation of Prdm16 as a Cause of Cardiomyopathy. Arndt, A. K., Schafer, S., Drenckhahn, J. D., Sabeh, M. K., Plovie, E. R., Caliebe, A., Klopocki, E., Musso, G., Werdich, A. A., Kalwa, H., Heinig, M., Padera, R. F., Wassilew, K., Bluhm, J., Harnack, C., Martitz, J., Barton, P. J., Greutmann, M., Berger, F., Hubner, N. et al. American journal of human genetics, (2013).

Sdf-1 Fused to a Fractalkine Stalk and a Gpi Anchor Enables Functional Neovascularization. Stachel, G., Trenkwalder, T., Gotz, F., El Aouni, C., Muenchmeier, N., Pfosser, A., Nussbaum, C., Sperandio, M., Hatzopoulos, A. K., Hinkel, R., Jon Nelson, P. & Kupatt, C. Stem cells, (2013).

Release Kinetics of Circulating Muscle-Enriched Micrornas in Patients Undergoing Transcoronary Ablation of Septal Hypertrophy. Liebetrau, C., Mollmann, H., Dorr, O., Szardien, S., Troidl, C., Willmer, M., Voss, S., Gaede, L., Rixe, J., Rolf, A., Hamm, C. & Nef, H. Journal of the American College of Cardiology, (2013).

Activation of K 3.1 by Ska-31 Induces Arteriolar Dilation and Lowers Blood Pressure in Normo- and Hypertensive Connexin40-Deficient Mice. Radtke, J., Schmidt, K., Wulff, H., Kohler, R. & de Wit, C. British journal of pharmacology, (2013).

Role of Oxidants on Calcium and Sodium Movement in Healthy and Diseased Cardiac Myocytes. Sag, C. M., Wagner, S. & Maier, L. S. Free radical biology & medicine 63C, 338-349, (2013).

Kcnq1 Autoantibodies: Another Way to Regulate Iks. Heijman, J. & Dobrev, D. Cardiovascular research 98, 329-331, (2013).

Positive Association between Testosterone, Blood Pressure, and Hypertension in Women: Longitudinal Findings from the Study of Health in Pomerania. Ziemens, B., Wallaschofski, H., Volzke, H., Rettig, R., Dorr, M., Nauck, M., Keevil, B. G., Brabant, G. & Haring, R. Journal of hypertension 31, 1106-1113, (2013).

Crossroads of Coagulation and Innate Immunity: The Case of Deep Vein Thrombosis. Schulz, C., Engelmann, B. & Massberg, S. Journal of thrombosis and haemostasis : JTH 11 Suppl 1, 233-241, (2013).

Sex-Stratified Genome-Wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. Randall, J. C., Winkler, T. W., Kutalik, Z., Berndt, S. I., Jackson, A. U., Monda, K. L., Kilpelainen, T. O., Esko, T., Magi, R., Li, S., Workalemahu, T., Feitosa, M. F., Croteau-Chonka, D. C., Day, F. R., Fall, T., Ferreira, T., Gustafsson, S., Locke, A. E., Mathieson, I., Scherag, A. et al. PLoS genetics 9, e1003500, (2013).

While Systolic Cardiomyocyte Function Is Preserved, Diastolic Myocyte Function and Recovery from Acidosis Are Impaired in Camkiidelta-Ko Mice. Neef, S., Sag, C. M., Daut, M., Baumer, H., Grefe, C., El-Armouche, A., Desantiago, J., Pereira, L., Bers, D. M., Backs, J. & Maier, L. S. Journal of molecular and cellular cardiology 59, 107-116, (2013).

Genetics of Coronary Artery Disease and Myocardial Infarction--2013. Kessler, T., Erdmann, J. & Schunkert, H. Current cardiology reports 15, 368, (2013).

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Dapper-1 Induces Myocardial Remodeling through Activation of Canonical Wnt Signaling in Cardiomyocytes. Hagenmueller, M., Riffel, J. H., Bernhold, E., Fan, J., Zhang, M., Ochs, M., Steinbeisser, H., Katus, H. A. & Hardt, S. E. Hypertension 61, 1177-1183, (2013).

Pde4 in the Human Heart - Major Player or Little Helper? Eschenhagen, T. British journal of pharmacology 169, 524-527, (2013).

Genetics of Atherosclerosis and Vascular Calcification Go Hand-in-Hand. Aherrahrou, Z. & Schunkert, H. Atherosclerosis 228, 325-326, (2013).

Rescue of Cardiomyopathy through U7snrna-Mediated Exon Skipping in Mybpc3-Targeted Knock-in Mice. Gedicke-Hornung, C., Behrens-Gawlik, V., Reischmann, S., Geertz, B., Stimpel, D., Weinberger, F., Schlossarek, S., Precigout, G., Braren, I., Eschenhagen, T., Mearini, G., Lorain, S., Voit, T., Dreyfus, P. A., Garcia, L. & Carrier, L. EMBO molecular medicine, (2013).

Mir-378 Controls Cardiac Hypertrophy by Combined Repression of Mitogen-Activated Protein Kinase Pathway Factors. Ganesan, J., Ramanujam, D., Sassi, Y., Ahles, A., Jentzsch, C., Werfel, S., Leierseder, S., Loyer, X., Giacca, M., Zentilin, L., Thum, T., Laggerbauer, B. & Engelhardt, S. Circulation 127, 2097-2106, (2013).

Cardiolipin Deficiency Affects Respiratory Chain Function and Organization in an Induced Pluripotent Stem Cell Model of Barth Syndrome. Dudek, J., Cheng, I. F., Balleininger, M., Vaz, F. M., Streckfuss-Bomeke, K., Hubscher, D., Vukotic, M., Wanders, R. J., Rehling, P. & Guan, K. Stem cell research 11, 806-819, (2013).

[Blood Pressure in Germany 2008-2011 : Results of the German Health Interview and Examination Survey for Adults (Degs1).]. Neuhauser, H., Thamm, M. & Ellert, U. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 56, 795-801, (2013).

Combined Sequence-Based and Genetic Mapping Analysis of Complex Traits in Outbred Rats. Rat Genome, S., Mapping, C., Baud, A., Hermsen, R., Guryev, V., Stridh, P., Graham, D., McBride, M. W., Foroud, T., Calderari, S., Diez, M., Ockinger, J., Beyeen, A. D., Gillett, A., Abdelmagid, N., Guerreiro-Cacais, A. O., Jagodic, M., Tuncel, J., Norin, U., Beattie, E. et al. Nature genetics, (2013).

Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy with Missense Sarcomeric Gene Mutations. Sequeira, V., Wijnker, P. J., Nijenkamp, L. L., Kuster, D. W., Najafi, A., Witjas-Paalberends, E. R., Regan, J. A., Boontje, N., Ten Cate, F. J., Germans, T., Carrier, L., Sadayappan, S., van Slegtenhorst, M. A., Zaremba, R., Foster, D. B., Murphy, A. M., Poggesi, C., Dos Remedios, C., Stienen, G. J., Ho, C. Y. et al. Circulation research 112, 1491-1505, (2013).

S151a Delta-Sarcoglycan Mutation Causes a Mild Phenotype of Cardiomyopathy in Mice. Rutschow, D., Bauer, R., Gohringer, C., Bekeredjian, R., Schinkel, S., Straub, V., Koenen, M., Weichenhan, D., Katus, H. A. & Muller, O. J. European journal of human genetics : EJHG, (2013).

Early Venous Manifestation of Ehlers-Danlos Syndrome Type Iv through a Novel Mutation in Col3a1. Wendorff, H., Pelisek, J., Zimmermann, A., Mayer, K., Seidel, H., Weirich, G., Hausser, I., Siegel, C., Zernecke, A. & Eckstein, H. H. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, (2013).

Prosthesis Sizing for Transcatheter Aortic Valve Implantation - Comparison of Three Dimensional Transesophageal Echocardiography with Multislice Computed Tomography. Husser, O., Holzamer, A., Resch, M., Endemann, D. H., Nunez, J., Bodi, V., Schmid, C., Riegger, G. A., Gossmann, H., Hamer, O., Stroszczynski, C., Luchner, A., Hilker, M. & Hengstenberg, C. International journal of cardiology, (2013).

Provocation of an Autoimmune Response to Cardiac Voltage-Gated Sodium Channel Na1.5 Induces Cardiac Conduction Defects in Rats. Korkmaz, S., Zitron, E., Bangert, A., Seyler, C., Li, S., Hegedus, P., Scherer, D., Li, J., Fink, T., Schweizer, P. A., Giannitsis, E., Karck, M., Szabo, G., Katus, H. A. & Kaya, Z. Journal of the American College of Cardiology, (2013).

Monoamine Oxidases Are Mediators of Endothelial Dysfunction in the Mouse Aorta. Sturza, A., Leisegang, M. S., Babelova, A., Schroder, K., Benkhoff, S., Loot, A. E., Fleming, I., Schulz, R., Muntean, D. M. & Brandes, R. P. Hypertension, (2013).

Immunomodulatory Effects of Mesenchymal Stromal Cells Revisited in the Context of Inflammatory Cardiomyopathy. Miteva, K., Van Linthout, S., Volk, H. D. & Tschope, C. Stem cells international 2013, 353097, (2013).

Sex Differences in Noninvasive Vascular Function in the Community. Schnabel, R. B., Biener, M. P., Wilde, S., Sinning, C. R., Ojeda, F. M., Zeller, T., Lubos, E., Lackner, K. J., Warnholtz, A., Gori, T., Espinola-Klein, C., Blankenberg, S., Munzel, T. & Wild, P. S. Journal of hypertension, (2013).

The Human Transcriptome Is Enriched for Mirna-Binding Sites Located in Cooperativity-Permitting Distance. Rinck, A., Preusse, M., Laggerbauer, B., Lickert, H., Engelhardt, S. & Theis, F. J. RNA biology 10, (2013).

Functional Interaction of Osteogenic Transcription Factors Runx2 and Vdr in Transcriptional Regulation of Opn During Soft Tissue Calcification. Sowa, A. K., Kaiser, F. J., Eckhold, J., Kessler, T., Aherrahrou, R., Wrobel, S., Kaczmarek, P. M., Doehring, L., Schunkert, H., Erdmann, J. & Aherrahrou, Z. The American journal of pathology, (2013).

Age-Dependent Yield of Screening for Undetected Atrial Fibrillation in Stroke Patients: The Find-Af Study. Wachter, R., Weber-Kruger, M., Seegers, J., Edelmann, F., Wohlfahrt, J., Wasser, K., Gelbrich, G., Hasenfuss, G., Stahrenberg, R., Liman, J. & Groschel, K. Journal of neurology, (2013).

Imaging T-Tubules: Dynamic Membrane Structures for Deep Functions. Kohl, T. & Lehnart, S. E. Cardiovascular research 98, 162-164, (2013).

The Four and a Half Lim-Domain 2 Controls Early Cardiac Cell Commitment and Expansion Via Regulating Beta-Catenin-Dependent Transcription. Renger, A., Zafiriou, M. P., Noack, C., Pavlova, E., Becker, A., Sharkova, K., Bergmann, M. W., El-Armouche, A., Zimmermann, W. H. & Zelarayan, L. C. Stem cells 31, 928-940, (2013).

Association of Hypertension with Depression in the Community: Results from the Gutenberg Health Study. Michal, M., Wiltink, J., Lackner, K., Wild, P. S., Zwiener, I., Blettner, M., Munzel, T., Schulz, A., Kirschner, Y. & Beutel, M. E. Journal of hypertension 31, 893-899, (2013).

Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk. Lieb, W., Jansen, H., Loley, C., Pencina, M. J., Nelson, C. P., Newton-Cheh, C., Kathiresan, S., Reilly, M. P., Assimes, T. L., Boerwinkle, E., Hall, A. S., Hengstenberg, C., Laaksonen, R., McPherson, R., Thorsteinsdottir, U., Ziegler, A., Peters, A., Thompson, J. R., Konig, I. R., Erdmann, J. et al. Hypertension 61, 995-1001, (2013).

The Ca-Calmodulin Dependent Kinase Ii: A Promising Target for Future Antiarrhythmic Therapies? Fischer, T. H., Neef, S. & Maier, L. S. Journal of molecular and cellular cardiology 58, 182-187, (2013).

Galectin-3 in Heart Failure with Preserved Ejection Fraction. de Boer, R. A., Edelmann, F., Cohen-Solal, A., Mamas, M. A., Maisel, A. & Pieske, B. European journal of heart failure, (2013).

Impact of Ankrd1 Mutations Associated with Hypertrophic Cardiomyopathy on Contraction Parameters of Engineered Heart Tissue. Crocini, C., Arimura, T., Reischmann, S., Eder, A., Braren, I., Hansen, A., Eschenhagen, T., Kimura, A. & Carrier, L. Basic research in cardiology 108, 349, (2013).

Assessment of Coronary Artery Stenosis Severity and Location: Quantitative Analysis of Transmural Perfusion Gradients by High-Resolution Mri Versus Ffr. Chiribiri, A., Hautvast, G. L., Lockie, T., Schuster, A., Bigalke, B., Olivotti, L., Redwood, S. R., Breeuwer, M., Plein, S. & Nagel, E. JACC. Cardiovascular imaging 6, 600-609, (2013).

Mir-378 Controls Cardiac Hypertrophy by Combined Repression of Map Kinase Pathway Factors. Ganesan, J., Ramanujam, D., Sassi, Y., Ahles, A., Jentzsch, C., Werfel, S., Leierseder, S., Loyer, X., Giacca, M., Zentilin, L., Thum, T., Laggerbauer, B. & Engelhardt, S. Circulation, (2013).

Genome-Wide Meta-Analysis Identifies 11 New Loci for Anthropometric Traits and Provides Insights into Genetic Architecture. Berndt, S. I., Gustafsson, S., Magi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T., Fall, T., Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W. et al. Nature genetics 45, 501-512, (2013).

Genome-Wide and Gene-Centric Analyses of Circulating Myeloperoxidase Levels in the Charge and Care Consortia. Reiner, A. P., Hartiala, J., Zeller, T., Bis, J. C., Dupuis, J., Fornage, M., Baumert, J., Kleber, M. E., Wild, P. S., Baldus, S., Bielinski, S. J., Fontes, J. D., Illig, T., Keating, B. J., Lange, L. A., Ojeda, F., Muller-Nurasyid, M., Munzel, T. F., Psaty, B. M., Rice, K. et al. Hum Mol Genet, (2013).

Heterozygous Lmnadelk32 Mice Develop Dilated Cardiomyopathy through a Combined Pathomechanism of Haploinsufficiency and Peptide Toxicity. Cattin, M. E., Bertrand, A. T., Schlossarek, S., Le Bihan, M. C., Skov Jensen, S., Neuber, C., Crocini, C., Maron, S., Laine, J., Mougenot, N., Varnous, S., Fromes, Y., Hansen, A., Eschenhagen, T., Decostre, V., Carrier, L. & Bonne, G. Hum Mol Genet, (2013).

Safety and Efficacy of Vernakalant for Acute Cardioversion of Atrial Fibrillation: An Update. Tsuji, Y. & Dobrev, D. Vascular health and risk management 9, 165-175, (2013).

Micrornas in Flow-Dependent Vascular Remodeling. Neth, P., Nazari-Jahantigh, M., Schober, A. & Weber, C. Cardiovascular research, (2013).

[Heart or Brain? : Problem Patients at the Interface between Cardiology and Neurology.]. Groschel, K., Rother, J., Laufs, U., Wachter, R., Fur die Arbeitsgemeinschaft, H. & Hirn der Deutschen Schlaganfall-Gesellschaft und der Deutschen Gesellschaft fur Kardiologie - Herz- und Kreislaufforschung e, V. Herz, (2013).

Hepatic Steatosis Is Associated with Aortic Valve Sclerosis in the General Population: The Study of Health in Pomerania (Ship). Markus, M. R., Baumeister, S. E., Stritzke, J., Dorr, M., Wallaschofski, H., Volzke, H. & Lieb, W. Arteriosclerosis, thrombosis, and vascular biology 33, 1690-1695, (2013).

Treatment of Coronary Drug-Eluting Stent Restenosis: A Journey Back to the Future? King, L. A., Kastrati, A. & Byrne, R. A. Expert review of medical devices 10, 423-427, (2013).

Development of a Colorimetric and a Fluorescence Phosphatase-Inhibitor Assay Suitable for Drug Discovery Approaches. Sotoud, H., Gribbon, P., Ellinger, B., Reinshagen, J., Boknik, P., El-Armouche, A. & Eschenhagen, T. Journal of biomolecular screening, (2013).

Robustness of Methods for Blinded Sample Size Re-Estimation with Overdispersed Count Data. Schneider, S., Schmidli, H. & Friede, T. Statistics in medicine, (2013).

The Microrna-342-5p Fosters Inflammatory Macrophage Activation through an Akt1- and Microrna-155-Dependent Pathway During Atherosclerosis. Wei, Y., Nazari-Jahantigh, M., Chan, L., Zhu, M., Heyll, K., Corbalan-Campos, J., Hartmann, P., Thiemann, A., Weber, C. & Schober, A. Circulation 127, 1609-1619, (2013).

Early Vessel Destabilization Mediated by Angiopoietin-2 and Subsequent Vessel Maturation Via Angiopoietin-1 Induce Functional Neovasculature after Ischemia. Qin, D., Trenkwalder, T., Lee, S., Chillo, O., Deindl, E., Kupatt, C. & Hinkel, R. PloS one 8, e61831, (2013).

Effects of Smoking on Arterial Distensibility, Central Aortic Pressures and Left Ventricular Mass. Markus, M. R., Stritzke, J., Baumeister, S. E., Siewert, U., Baulmann, J., Hannemann, A., Schipf, S., Meisinger, C., Dorr, M., Felix, S. B., Keil, U., Volzke, H., Hense, H. W., Schunkert, H. & The, M. K. A. C. S. International journal of cardiology, (2013).

Identification of Heart Rate-Associated Loci and Their Effects on Cardiac Conduction and Rhythm Disorders. den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J., Peal, D. S., Evans, D. M., Nolte, I. M., Segre, A. V., Holm, H., Handsaker, R. E., Westra, H. J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., Bochud, M. et al. Nature genetics, (2013).

Amp-Activated Protein Kinase Regulates Endothelial Cell Angiotensin-Converting Enzyme Expression Via P53 and the Post-Transcriptional Regulation of Microrna-143/145. Kohlstedt, K., Trouvain, C., Boettger, T., Shi, L., Fisslthaler, B. & Fleming, I. Circulation research 112, 1150-1158, (2013).

The Role of Co-Morbidity in the Selection of Antidiabetic Pharmacotherapy in Type-2 Diabetes. Tschope, D., Hanefeld, M., Meier, J. J., Gitt, A. K., Halle, M., Bramlage, P. & Schumm-Draeger, P. M. Cardiovascular diabetology 12, 62, (2013).

Role of Late Sodium Current as a Potential Arrhythmogenic Mechanism in the Progression of Pressure-Induced Heart Disease. Toischer, K., Hartmann, N., Wagner, S., Fischer, T. H., Herting, J., Danner, B. C., Sag, C. M., Hund, T. J., Mohler, P. J., Belardinelli, L., Hasenfuss, G., Maier, L. S. & Sossalla, S. Journal of molecular and cellular cardiology, (2013).

Pathogenic Arterial Remodeling: The Good and Bad of Micrornas. Wei, Y., Schober, A. & Weber, C. American journal of physiology. Heart and circulatory physiology 304, H1050-1059, (2013).

Ranolazine for the Treatment of Diastolic Heart Failure in Patients with Preserved ejection Fraction. Maier, L. S., Layug, B., Karwatowska-Prokopczuk, E., Belardinelli, L., Lee, S., Sander, J., Lang, C., Wachter, R., Edelmann, F., Hasenfuss, G. & Jacobshagen, C. JACC: Heart Failure 1, 115-122, (2013).

Functional Maturation of Left and Right Atrial Systolic and Diastolic Performance in Infants, Children, and Adolescents. Kutty, S., Padiyath, A., Li, L., Peng, Q., Rangamani, S., Schuster, A. & Danford, D. A. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 26, 398-409 e392, (2013).

Somatic Mutations in Atp1a1 and Atp2b3 Lead to Aldosterone-Producing Adenomas and Secondary Hypertension. Beuschlein, F., Boulkroun, S., Osswald, A., Wieland, T., Nielsen, H. N., Lichtenauer, U. D., Penton, D., Schack, V. R., Amar, L., Fischer, E., Walther, A., Tauber, P., Schwarzmayr, T., Diener, S., Graf, E., Allolio, B., Samson-Couterie, B., Benecke, A., Quinkler, M., Fallo, F. et al. Nature genetics 45, 440-444, 444e441-442, (2013).

Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: The Charge-Af Consortium. Alonso, A., Krijthe, B. P., Aspelund, T., Stepas, K. A., Pencina, M. J., Moser, C. B., Sinner, M. F., Sotoodehnia, N., Fontes, J. D., Janssens, A. C., Kronmal, R. A., Magnani, J. W., Witteman, J. C., Chamberlain, A. M., Lubitz, S. A., Schnabel, R. B., Agarwal, S. K., McManus, D. D., Ellinor, P. T., Larson, M. G. et al. Journal of the American Heart Association 2, e000102, (2013).

Cxcl12 Promotes the Stabilization of Atherosclerotic Lesions Mediated by Smooth Muscle Progenitor Cells in Apoe-Deficient Mice. Akhtar, S., Gremse, F., Kiessling, F., Weber, C. & Schober, A. Arteriosclerosis, thrombosis, and vascular biology 33, 679-686, (2013).

Impact of Ankrd1 Mutations Associated with Hypertrophic Cardiomyopathy on Cardiac Contraction Crocini, C., Arimura, T., Reischmann, S., Eder, A., Braren, I., Naito, H., Hansen, A., Eschenhagen, T., Kimura, A. & Carrier, L. Basic research in cardiology in press, (2013).  

Exercise Blood Pressure and Heart Rate Reference Values. Glaser, S., Friedrich, N., Koch, B., Schaper, C., Volzke, H., Felix, S. B., Empen, K., Hannemann, A., Ewert, R. & Dorr, M. Heart, lung & circulation, (2013).

Redox Regulation of Sodium and Calcium Handling. Wagner, S., Rokita, A. G., Anderson, M. E. & Maier, L. S. Antioxidants & redox signaling 18, 1063-1077, (2013).

Stimulating Stress Fibers in Endothelial Cells. Gudermann, T. & Steinritz, D. Science signaling 6, pe8, (2013).

Blinded Sample Size Re-Estimation in Superiority and Noninferiority Trials: Bias Versus Variance in Variance Estimation. Friede, T. & Kieser, M. Pharmaceutical statistics, (2013).

The Polarity Protein Scrib Is Essential for Directed Endothelial Cell Migration. Michaelis, U. R., Chavakis, E., Kruse, C., Jungblut, B., Kaluza, D., Wandzioch, K., Manavski, Y., Heide, H., Santoni, M. J., Potente, M., Eble, J. A., Borg, J. P. & Brandes, R. P. Circulation research 112, 924-934, (2013).

Endoscopic Time-Lapse Imaging of Immune Cells in Infarcted Mouse Hearts. Jung, K., Kim, P., Leuschner, F., Gorbatov, R., Kim, J. K., Ueno, T., Nahrendorf, M. & Yun, S. H. Circulation research 112, 891-899, (2013).

Kommentar Zu Den Leitlinien Der Europäischen Gesellschaft Für Kardiologie (Esc) Zur Diagnostik Und Behandlung Der Akuten Und Chronischen Herzinsuffizienz. Hasenfuß, G., Anker, S., Bauersachs, J., Böhm, M., Hoppe, U. C., Pieske, B., Scheidt, W. & Wachter, R. Der Kardiologe 7, 105-114, (2013).  

The Late Na Current as a Therapeutic Target: Where Are We? Maier, L. S. & Sossalla, S. Journal of molecular and cellular cardiology, (2013).

Phosphodiesterase 4 in the Human Heart - Major Player or Little Helper? Eschenhagen, T. British journal of pharmacology, (2013).

Microrna-34a Regulates Cardiac Ageing and Function. Boon, R. A., Iekushi, K., Lechner, S., Seeger, T., Fischer, A., Heydt, S., Kaluza, D., Treguer, K., Carmona, G., Bonauer, A., Horrevoets, A. J., Didier, N., Girmatsion, Z., Biliczki, P., Ehrlich, J. R., Katus, H. A., Muller, O. J., Potente, M., Zeiher, A. M., Hermeking, H. et al. Nature 495, 107-110, (2013).

Cytokine-Induced Oxidative Stress in Cardiac Inflammation and Heart Failure-How the Ubiquitin Proteasome System Targets This Vicious Cycle. Voigt, A., Rahnefeld, A., Kloetzel, P. M. & Kruger, E. Frontiers in physiology 4, 42, (2013).

Go with the Flow: The Passion for Vascular Biology Research. Highlights from Ivbm 2012. Preissner, K. T. & Weber, C. Thrombosis and haemostasis 109, 366-367, (2013).

Calmodulin Mutations Associated with Recurrent Cardiac Arrest in Infants. Crotti, L., Johnson, C. N., Graf, E., De Ferrari, G. M., Cuneo, B. F., Ovadia, M., Papagiannis, J., Feldkamp, M. D., Rathi, S. G., Kunic, J. D., Pedrazzini, M., Wieland, T., Lichtner, P., Beckmann, B. M., Clark, T., Shaffer, C., Benson, D. W., Kaab, S., Meitinger, T., Strom, T. M. et al. Circulation 127, 1009-1017, (2013).

Calmodulin Mutations Associated with Recurrent Cardiac Arrest in Infants. Crotti, L., Johnson, C. N., Graf, E., De Ferrari, G. M., Cuneo, B. F., Ovadia, M., Papagiannis, J., Feldkamp, M. D., Rathi, S. G., Kunic, J. D., Pedrazzini, M., Wieland, T., Lichtner, P., Beckmann, B. M., Clark, T., Shaffer, C., Benson, D. W., Kaab, S., Meitinger, T., Strom, T. M. et al. Circulation 127, 1009-1017, (2013).

Diabetes Increases Mortality after Myocardial Infarction by Oxidizing Camkii. Luo, M., Guan, X., Luczak, E. D., Lang, D., Kutschke, W., Gao, Z., Yang, J., Glynn, P., Sossalla, S., Swaminathan, P. D., Weiss, R. M., Yang, B., Rokita, A. G., Maier, L. S., Efimov, I. R., Hund, T. J. & Anderson, M. E. The Journal of clinical investigation 123, 1262-1274, (2013).

Hdac4 Controls Histone Methylation in Response to Elevated Cardiac Load. Hohl, M., Wagner, M., Reil, J. C., Muller, S. A., Tauchnitz, M., Zimmer, A. M., Lehmann, L. H., Thiel, G., Bohm, M., Backs, J. & Maack, C. The Journal of clinical investigation 123, 1359-1370, (2013).

Parthenogenetic Stem Cells for Tissue-Engineered Heart Repair. Didie, M., Christalla, P., Rubart, M., Muppala, V., Doker, S., Unsold, B., El-Armouche, A., Rau, T., Eschenhagen, T., Schwoerer, A. P., Ehmke, H., Schumacher, U., Fuchs, S., Lange, C., Becker, A., Tao, W., Scherschel, J. A., Soonpaa, M. H., Yang, T., Lin, Q. et al. The Journal of clinical investigation 123, 1285-1298, (2013).

[Genetic Testing Is Superior to Biopsy of the Myocardium in Cardiomyopathy - Yes]. Thanaraj, A. & Meder, B. Dtsch Med Wochenschr 138, 598, (2013).

Distinct Functions of Chemokine Receptor Axes in the Atherogenic Mobilization and Recruitment of Classical Monocytes. Soehnlein, O., Drechsler, M., Doring, Y., Lievens, D., Hartwig, H., Kemmerich, K., Ortega-Gomez, A., Mandl, M., Vijayan, S., Projahn, D., Garlichs, C. D., Koenen, R. R., Hristov, M., Lutgens, E., Zernecke, A. & Weber, C. EMBO molecular medicine 5, 471-481, (2013).

Understanding the Physiology of Heart Failure through Cellular and in Vivo Models-Towards Targeting of Complex Mechanisms. Lehnart, S. E. Experimental physiology 98, 622-628, (2013).

Alterations in Cardiac DNA Methylation in Human Dilated Cardiomyopathy. Haas, J., Frese, K. S., Park, Y. J., Keller, A., Vogel, B., Lindroth, A. M., Weichenhan, D., Franke, J., Fischer, S., Bauer, A., Marquart, S., Sedaghat-Hamedani, F., Kayvanpour, E., Kohler, D., Wolf, N. M., Hassel, S., Nietsch, R., Wieland, T., Ehlermann, P., Schultz, J. H. et al. EMBO molecular medicine 5, 413-429, (2013).

A Novel Genetic Variant in the Transcription Factor Islet-1 Exerts Gain of Function on Myocyte Enhancer Factor 2c Promoter Activity. Friedrich, F. W., Dilanian, G., Khattar, P., Juhr, D., Gueneau, L., Charron, P., Fressart, V., Vilquin, J. T., Isnard, R., Gouya, L., Richard, P., Hammoudi, N., Komajda, M., Bonne, G., Eschenhagen, T., Dubourg, O., Villard, E. & Carrier, L. European journal of heart failure 15, 267-276, (2013).

Nitric Oxide-Donating Statins Upgrade the Benefits of Lipid-Lowering in Vascular Inflammation by Desensitizing Neutrophil Activation : Editorial To: "Nitric Oxide-Donating Atorvastatin Attenuates Neutrophil Recruitment During Vascular Inflammation Independent of Changes in Plasma Cholesterol" by R. Baetta Et Al. Drechsler, M., Soehnlein, O. & Weber, C. Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, (2013).

Gap Junctional Communication Promotes Apoptosis in a Connexin-Type-Dependent Manner. Kameritsch, P., Khandoga, N., Pohl, U. & Pogoda, K. Cell death & disease 4, e584, (2013).

Ca2+ Sensing Receptor Cleavage by Calpain Partially Accounts for Altered Vascular Reactivity in Mice Fed a High Fat Diet. Loot, A. E., Pierson, I., Syzonenko, T., Elgheznawy, A., Randriamboavonjy, V., Zivkovic, A., Stark, H. & Fleming, I. Journal of cardiovascular pharmacology, (2013).

New Echocardiographic Findings Correlate with Intramyocardial Inflammation in Endomyocardial Biopsies of Patients with Acute Myocarditis and Inflammatory Cardiomyopathy. Escher, F., Kasner, M., Kuhl, U., Heymer, J., Wilkenshoff, U., Tschope, C. & Schultheiss, H. P. Mediators Inflamm 2013, 875420, (2013).

Gsk3beta Phosphorylates Newly Identified Site in the Proline-Alanine-Rich Region of Cardiac Myosin-Binding Protein C and Alters Cross-Bridge Cycling Kinetics in Human: Short Communication. Kuster, D. W., Sequeira, V., Najafi, A., Boontje, N. M., Wijnker, P. J., Witjas-Paalberends, E. R., Marston, S. B., Dos Remedios, C. G., Carrier, L., Demmers, J. A., Redwood, C., Sadayappan, S. & van der Velden, J. Circulation research 112, 633-639, (2013).

Crucial Role for Ca2(+)/Calmodulin-Dependent Protein Kinase-Ii in Regulating Diastolic Stress of Normal and Failing Hearts Via Titin Phosphorylation. Hamdani, N., Krysiak, J., Kreusser, M. M., Neef, S., Dos Remedios, C. G., Maier, L. S., Kruger, M., Backs, J. & Linke, W. A. Circulation research 112, 664-674, (2013).

High Resolution Real-Time Cmr of Function and Flow: Initial Clinical Results. Lotz, J., Sohns, J. M., Steinmetz, M., Kowallick, J. T., Schulte, C., Staab, W., Joseph, A., Merboldt, K.-D., Voit, D., Zhang, S., Uecker, M., Unterberg-Buchwald, C., Hasenfus, G. & Frahm, J. Journal of Cardiovascular Magnetic Resonance 15, E99, (2013).

Micrornas: From Basic Mechanisms to Clinical Application in Cardiovascular Medicine. Weber, C. Arteriosclerosis, thrombosis, and vascular biology 33, 168-169, (2013).

Subclinical Atrial Fibrillation: How Hard Should We Look? Wachter, R., Stahrenberg, R. & Groschel, K. Heart 99, 151-153, (2013).

Superresolution Microscopy in Heart - Cardiac Nanoscopy. Kohl, T., Westphal, V., Hell, S. W. & Lehnart, S. E. Journal of molecular and cellular cardiology 58, 13-21, (2013).

Refining Diagnostic Microrna Signatures by Whole-Mirnome Kinetic Analysis in Acute Myocardial Infarction. Vogel, B., Keller, A., Frese, K. S., Kloos, W., Kayvanpour, E., Sedaghat-Hamedani, F., Hassel, S., Marquart, S., Beier, M., Giannitis, E., Hardt, S., Katus, H. A. & Meder, B. Clinical chemistry 59, 410-418, (2013).

The Relationship between Depressive Symptoms and Restless Legs Syndrome in Two Prospective Cohort Studies. Szentkiralyi, A., Volzke, H., Hoffmann, W., Baune, B. T. & Berger, K. Psychosom Med 75, 359-365, (2013).

Electrical Storm: Recent Pathophysiological Insights and Therapeutic Consequences. Tsuji, Y., Heijman, J., Nattel, S. & Dobrev, D. Basic research in cardiology 108, 336, (2013).

Interventional Vascular Mri: Moving Forward. Lotz, J. European heart journal 34, 327-329, (2013).

Atrial Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia--Is There a Mechanistic Link between Sarcoplasmic Reticulum Ca(2+) Leak and Re-Entry? Heijman, J., Wehrens, X. H. & Dobrev, D. Acta physiologica 207, 208-211, (2013).

Muscle Wasting in Patients with Chronic Heart Failure: Results from the Studies Investigating Co-Morbidities Aggravating Heart Failure (Sica-Hf). Fulster, S., Tacke, M., Sandek, A., Ebner, N., Tschope, C., Doehner, W., Anker, S. D. & von Haehling, S. European heart journal 34, 512-519, (2013).

Micrornas in Age-Related Diseases. Dimmeler, S. & Nicotera, P. EMBO molecular medicine 5, 180-190, (2013).

The Potassium Channel Kca3.1 as New Therapeutic Target for the Prevention of Obliterative Airway Disease. Hua, X., Deuse, T., Chen, Y. J., Wulff, H., Stubbendorff, M., Kohler, R., Miura, H., Langer, F., Reichenspurner, H., Robbins, R. C. & Schrepfer, S. Transplantation 95, 285-292, (2013).

Novel Single-Source High-Pitch Protocol for Ct Angiography of the Aorta: Comparison to High-Pitch Dual-Source Protocol in the Context of Tavi Planning. Bischoff, B., Meinel, F. G., Reiser, M. & Becker, H. C. The international journal of cardiovascular imaging, (2013).

S100a1 Deficiency Impairs Postischemic Angiogenesis Via Compromised Proangiogenic Endothelial Cell Function and Nitric Oxide Synthase Regulation. Most, P., Lerchenmuller, C., Rengo, G., Mahlmann, A., Ritterhoff, J., Rohde, D., Goodman, C., Busch, C. J., Laube, F., Heissenberg, J., Pleger, S. T., Weiss, N., Katus, H. A., Koch, W. J. & Peppel, K. Circulation research 112, 66-78, (2013).

The Role of Promoter Hypermethylation in Fibroblast Activation and Fibrogenesis. Zeisberg, E. M. & Zeisberg, M. The Journal of pathology 229, 264-273, (2013).

Selective Pde5a Inhibition with Sildenafil Rescues Left Ventricular Dysfunction, Inflammatory Immune Response and Cardiac Remodeling in Angiotensin Ii-Induced Heart Failure in Vivo. Westermann, D., Becher, P. M., Lindner, D., Savvatis, K., Xia, Y., Frohlich, M., Hoffmann, S., Schultheiss, H. P. & Tschope, C. Basic research in cardiology 107, 308, (2012).

[Magnetic Resonance Imaging of Hypertrophic Cardiomyopathy : Evaluation of Diastolic Function]. Schwarz, F., Schwab, F., Beckmann, B. M., Schuessler, F., Zinsser, D., Golz, T., Kaab, S., Reiser, M. F. & Theisen, D. Der Radiologe 53, 15-23, (2013).

New Directions in Antiarrhythmic Drug Therapy for Atrial Fibrillation. Heijman, J., Voigt, N. & Dobrev, D. Future cardiology 9, 71-88, (2013).

Cytochrome P4502s1: A Novel Monocyte/Macrophage Fatty Acid Epoxygenase in Human Atherosclerotic Plaques. Fromel, T., Kohlstedt, K., Popp, R., Yin, X., Awwad, K., Barbosa-Sicard, E., Thomas, A. C., Lieberz, R., Mayr, M. & Fleming, I. Basic research in cardiology 108, 319, (2013).

A Frequent Gene Polymorphism Affecting the Heart-Rate Response to Carvedilol. Eschenhagen, T. Pharmacogenomics 14, 115-118, (2013).

New Tissue for Failing Hearts. Eschenhagen, T. European journal of heart failure 15, 1-2, (2013).

[Magnetic Resonance Imaging of Dilated Cardiomyopathy]. D'Anastasi, M., Greif, M., Reiser, M. F. & Theisen, D. Der Radiologe 53, 24-29, (2013).

Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+ Transients and Membrane Currents. Voigt, N., Zhou, X. B. & Dobrev, D. Journal of visualized experiments : JoVE, (2013).

Serum Prolactin Concentrations as Risk Factor of Metabolic Syndrome or Type 2 Diabetes? Balbach, L., Wallaschofski, H., Volzke, H., Nauck, M., Dorr, M. & Haring, R. BMC endocrine disorders 13, 12, (2013).

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