Publikationen 2022

Hier finden Sie die Publikationen des DZHK. Grau markierte Erstautoren sind DZHK-Nachwuchswissenschaftler. Bitte informieren Sie sich über weitere Publikationen auch auf den Internetseiten der am DZHK beteiligten Forschungseinrichtungen.

Zu den DZHK Papers of the Month

April

Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study. Valerio, L., Mavromanoli, A. C., Barco, S., Abele, C., Becker, D., Bruch, L., Ewert, R., Faehling, M., Fistera, D., Gerhardt, F., Ghofrani, H. A., Grgic, A., Grunig, E., Halank, M., Held, M., Hobohm, L., Hoeper, M. M., Klok, F. A., Lankeit, M., Leuchte, H. H., Martin, N., Mayer, E., Meyer, F. J., Neurohr, C., Opitz, C., Schmidt, K. H., Seyfarth, H. J., Wachter, R., Wilkens, H., Wild, P. S., Konstantinides, S. V., Rosenkranz, S. & Investigators, F. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35484821  

Establishing a robotic-assisted PCI program: experiences at a large tertiary referral center. Brunner, F. J., Waldeyer, C., Zengin-Sahm, E., Kondziella, C., Schrage, B., Clemmensen, P., Westermann, D., Blankenberg, S. & Seiffert, M. Heart Vessels (2022). https://www.ncbi.nlm.nih.gov/pubmed/35487996

Computational and experimental methods for classifying variants of unknown clinical significance. Spielmann, M. & Kircher, M. Cold Spring Harb Mol Case Stud 8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35483875  

Neuroimmune cardiovascular interfaces control atherosclerosis. Mohanta, S. K., Peng, L., Li, Y., Lu, S., Sun, T., Carnevale, L., Perrotta, M., Ma, Z., Forstera, B., Stanic, K., Zhang, C., Zhang, X., Szczepaniak, P., Bianchini, M., Saeed, B. R., Carnevale, R., Hu, D., Nosalski, R., Pallante, F., Beer, M., Santovito, D., Erturk, A., Mettenleiter, T. C., Klupp, B. G., Megens, R. T. A., Steffens, S., Pelisek, J., Eckstein, H. H., Kleemann, R., Habenicht, L., Mallat, Z., Michel, J. B., Bernhagen, J., Dichgans, M., D'Agostino, G., Guzik, T. J., Olofsson, P. S., Yin, C., Weber, C., Lembo, G., Carnevale, D. & Habenicht, A. J. R. Nature 605, 152-159 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35477759  

A machine learning algorithm for electrocardiographic fQRS quantification validated on multi-center data. Villa, A., Vandenberk, B., Kentta, T., Ingelaere, S., Huikuri, H. V., Zabel, M., Friede, T., Sticherling, C., Tuinenburg, A., Malik, M., Van Huffel, S., Willems, R. & Varon, C. Sci Rep 12, 6783 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35474073  

Periprocedural myocardial injury according to optical characteristics of neointima and treatment modality of in-stent restenosis. Nano, N., Aytekin, A., Ndrepepa, G., Seguchi, M., Bresha, J., Alvarez Covarrubias, H. A., Nicol, P., Lenz, T., Lahu, S., Gewalt, S., Voll, F., Rheude, T., Wiebe, J., Schunkert, H., Kufner, S., Cassese, S., Joner, M., Kastrati, A. & Xhepa, E. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35476138  

Effect of obesity on the associations of 25-hydroxyvitamin D with prevalent and incident distal sensorimotor polyneuropathy: population-based KORA F4/FF4 study. Maalmi, H., Herder, C., Huth, C., Rathmann, W., Bonhof, G. J., Heier, M., Koenig, W., Roden, M., Peters, A., Ziegler, D. & Thorand, B. Int J Obes (Lond) 46, 1366-1374 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35474356  

Serial Assessment of Right Ventricular Deformation in Patients With Hypoplastic Left Heart Syndrome: A Cardiovascular Magnetic Resonance Feature Tracking Study. Kanngiesser, L. M., Freitag-Wolf, S., Boroni Grazioli, S., Gabbert, D. D., Hansen, J. H., Uebing, A. S. & Voges, I. J Am Heart Assoc 11, e025332 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35475354  

Exome sequencing in individuals with cardiovascular laterality defects identifies potential candidate genes. Breuer, K., Riedhammer, K. M., Muller, N., Schaidinger, B., Dombrowsky, G., Dittrich, S., Zeidler, S., Bauer, U. M. M., Westphal, D. S., Meitinger, T., Dakal, T. C., Hitz, M. P., Breuer, J., Reutter, H., Hilger, A. C. & Hoefele, J. Eur J Hum Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35474353  

Stent Optimization Using Optical Coherence Tomography and Its Prognostic Implications After Percutaneous Coronary Intervention. Rai, H., Harzer, F., Otsuka, T., Abdelwahed, Y. S., Antuna, P., Blachutzik, F., Koppara, T., Raber, L., Leistner, D. M., Alfonso, F., Nef, H., Seguchi, M., Aytekin, A., Xhepa, E., Kufner, S., Cassese, S., Laugwitz, K. L., Byrne, R. A., Kastrati, A. & Joner, M. J Am Heart Assoc 11, e02393 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35470682  

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI. Kaiser, R., Escaig, R., Kranich, J., Hoffknecht, M. L., Anjum, A., Polewka, V., Mader, M., Hu, W., Belz, L., Gold, C., Titova, A., Lorenz, M., Pekayvaz, K., Kaab, S., Gaertner, F., Stark, K., Brocker, T., Massberg, S. & Nicolai, L. Blood (2022). https://www.ncbi.nlm.nih.gov/pubmed/35472164  

Towards lower radiation and contrast media dose CT angiography of the aorta by artificial intelligence-supported iterative reconstructions. Halfmann, M. C. & Emrich, T. Eur J Radiol 151, 110327 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35472648  

Which patients with aortic stenosis should be referred to surgery rather than transcatheter aortic valve implantation? Windecker, S., Okuno, T., Unbehaun, A., Mack, M., Kapadia, S. & Falk, V. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35466382  

Cardiac Cachexia Revisited: The Role of Wasting in Heart Failure. Valentova, M., Anker, S. D. & von Haehling, S. Cardiol Clin 40, 199-207 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35465894  

[Cost-benefit analysis of new lipid-lowering agents]. Blaum, C., Arnold, N. & Waldeyer, C. Herz 47, 236-243 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35467096  

Temporary mechanical circulatory support: Devices, outcomes, and future directions. Baran, D. A., Jaiswal, A., Hennig, F. & Potapov, E. J Heart Lung Transplant 41, 678-691 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35461760  

Clinical Profile, Arrhythmias, and Adverse Cardiac Outcomes in Emery-Dreifuss Muscular Dystrophies: A Systematic Review of the Literature. Valenti, A. C., Albini, A., Imberti, J. F., Vitolo, M., Bonini, N., Lattanzi, G., Schnabel, R. B. & Boriani, G. Biology (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35453731  

Treatment of Transthyretin Amyloid Cardiomyopathy: The Current Options, the Future, and the Challenges. Tschope, C. & Elsanhoury, A. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35456241  

Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations. Spehlmann, M. E., Rangrez, A. Y., Dhotre, D. P., Schmiedel, N., Chavan, N., Bang, C., Muller, O. J., Shouche, Y. S., Franke, A., Frank, D. & Frey, N. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35453559  

Therapeutic Alternatives in Diabetic Foot Patients without an Option for Revascularization: A Narrative Review. Ruemenapf, G., Morbach, S. & Sigl, M. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35456247  

Validation of the 30-Year Framingham Risk Score in a German Population-Based Cohort. Rospleszcz, S., Starnecker, F., Linkohr, B., von Scheidt, M., Gieger, C., Schunkert, H., Peters, A. & DigiMed Bayern, C. Diagnostics (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35454012  

Prediction of Successful Pharmacological Cardioversion in Acute Symptomatic Atrial Fibrillation: The Successful Intravenous Cardioversion for Atrial Fibrillation (SIC-AF) Score. Niederdockl, J. D., Simon, A., Buchtele, N., Schutz, N., Cacioppo, F., Oppenauer, J., Gupta, S., Lutnik, M., Schnaubelt, S., Spiel, A., Roth, D., Wimbauer, F., Fegers-Wustrow, I., Esefeld, K., Halle, M., Scharhag, J., Laschitz, T., Herkner, H., Domanovits, H. & Schwameis, M. J Pers Med 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35455660  

Straightforward Analysis of Sulfated Glycosaminoglycans by MALDI-TOF Mass Spectrometry from Biological Samples. Kruger, L., Biskup, K., Karampelas, V., Ludwig, A., Kasper, A. S., Poller, W. C. & Blanchard, V. Biology (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35453706  

Simultaneous Quantification and Pharmacokinetic Characterization of Doxapram and 2-Ketodoxapram in Porcine Plasma and Brain Tissue. Kraft, M., Foerster, K. I., Wiedmann, F., Sauter, M., Paasche, A., Blochberger, P. L., Yesilgoz, B., L'Hoste, Y., Frey, N., Haefeli, W. E., Burhenne, J. & Schmidt, C. Pharmaceutics 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35456597  

The Structural and the Functional Aspects of Intercellular Communication in iPSC-Cardiomyocytes. Kiss, E., Fischer, C., Sauter, J. M., Sun, J. & Ullrich, N. D. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35457277  

Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging. Hadler, T., Wetzl, J., Lange, S., Geppert, C., Fenski, M., Abazi, E., Groschel, J., Ammann, C., Wenson, F., Topper, A., Dauber, S. & Schulz-Menger, J. Sci Rep 12, 6629 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35459270  

Pooled Analysis of Complications with Transvenous ICD Compared to Subcutaneous ICD in Patients with Catecholaminergic Polymorphic Ventricular Arrhythmia. Eckert, H., El-Battrawy, I., Veith, M., Roterberg, G., Kowitz, J., Lang, S., Zhou, X., Akin, I., Mugge, A. & Aweimer, A. J Pers Med 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35455651   

Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay. Wallmeroth, D., Lackmann, J. W., Kueckelmann, S., Altmuller, J., Dieterich, C., Boehm, V. & Gehring, N. H. EMBO J, e109191 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451084  

Definition, Classification and Diagnosis of Diabetes Mellitus. Schleicher, E., Gerdes, C., Petersmann, A., Muller-Wieland, D., Muller, U. A., Freckmann, G., Heinemann, L., Nauck, M. & Landgraf, R. Exp Clin Endocrinol Diabetes (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451038  

Microbiota-derived tryptophan metabolites in vascular inflammation and cardiovascular disease. Paeslack, N., Mimmler, M., Becker, S., Gao, Z., Khuu, M. P., Mann, A., Malinarich, F., Regen, T. & Reinhardt, C. Amino Acids (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451695  

Assessment of Myocardial Microstructure in a Murine Model of Obesity-Related Cardiac Dysfunction by Diffusion Tensor Magnetic Resonance Imaging at 7T. Lohr, D., Thiele, A., Stahnke, M., Braun, V., Smeir, E., Spranger, J., Brachs, S., Klopfleisch, R., Foryst-Ludwig, A., Schreiber, L. M., Kintscher, U. & Beyhoff, N. Front Cardiovasc Med 9, 839714 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35449873  

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK-STAT signaling in macrophages by perturbing lipid raft structures. Hammoud, M. K., Dietze, R., Pesek, J., Finkernagel, F., Unger, A., Bieringer, T., Nist, A., Stiewe, T., Bhagwat, A. M., Nockher, W. A., Reinartz, S., Muller-Brusselbach, S., Graumann, J. & Muller, R. Mol Oncol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451191  

Background calcium influx in arrhythmia: lead actor or extra? Fakuade, F. E., Fauconnier, J. & Voigt, N. J Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451079  

Optical coherence tomography in coronary atherosclerosis assessment and intervention. Araki, M., Park, S. J., Dauerman, H. L., Uemura, S., Kim, J. S., Di Mario, C., Johnson, T. W., Guagliumi, G., Kastrati, A., Joner, M., Holm, N. R., Alfonso, F., Wijns, W., Adriaenssens, T., Nef, H., Rioufol, G., Amabile, N., Souteyrand, G., Meneveau, N., Gerbaud, E., Opolski, M. P., Gonzalo, N., Tearney, G. J., Bouma, B., Aguirre, A. D., Mintz, G. S., Stone, G. W., Bourantas, C. V., Raber, L., Gili, S., Mizuno, K., Kimura, S., Shinke, T., Hong, M. K., Jang, Y., Cho, J. M., Yan, B. P., Porto, I., Niccoli, G., Montone, R. A., Thondapu, V., Papafaklis, M. I., Michalis, L. K., Reynolds, H., Saw, J., Libby, P., Weisz, G., Iannaccone, M., Gori, T., Toutouzas, K., Yonetsu, T., Minami, Y., Takano, M., Raffel, O. C., Kurihara, O., Soeda, T., Sugiyama, T., Kim, H. O., Lee, T., Higuma, T., Nakajima, A., Yamamoto, E., Bryniarski, K. L., Di Vito, L., Vergallo, R., Fracassi, F., Russo, M., Seegers, L. M., McNulty, I., Park, S., Feldman, M., Escaned, J., Prati, F., Arbustini, E., Pinto, F. J., Waksman, R., Garcia-Garcia, H. M., Maehara, A., Ali, Z., Finn, A. V., Virmani, R., Kini, A. S., Daemen, J., Kume, T., Hibi, K., Tanaka, A., Akasaka, T., Kubo, T., Yasuda, S., Croce, K., Granada, J. F., Lerman, A., Prasad, A., Regar, E., Saito, Y., Sankardas, M. A., Subban, V., Weissman, N. J., Chen, Y., Yu, B., Nicholls, S. J., Barlis, P., West, N. E. J., Arbab-Zadeh, A., Ye, J. C., Dijkstra, J., Lee, H., Narula, J., Crea, F., Nakamura, S., Kakuta, T., Fujimoto, J., Fuster, V. & Jang, I. K. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35449407  

Antiarrhythmic Effects of Vernakalant in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Short QT Syndrome Type 1. Xu, Q., Huang, X., Meng, Z., Li, Y., Zhong, R., Li, X., Cyganek, L., El-Battrawy, I., Akin, I., Zhou, X. & Lan, H. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35448088  

Heart failure in the general population and impact of the 2021 European Society of Cardiology Heart Failure Guidelines. Wenzel, J. P., Nikorowitsch, J., Bei der Kellen, R., Magnussen, C., Bonin-Schnabel, R., Westermann, D., Twerenbold, R., Kirchhof, P., Blankenberg, S. & Schrage, B. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35445582  

Quantitative Flow Ratio or Angiography for the Assessment of Non-culprit Lesions in Acute Coronary Syndromes: Protocol of the Randomized Trial QUOMODO. Ullrich, H., Olschewski, M., Belhadj, K. A., Munzel, T. & Gori, T. Front Cardiovasc Med 9, 815434 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35445090  

Depressive symptoms predict the incidence of common chronic diseases in women and men in a representative community sample. Otten, D., Ernst, M., Werner, A. M., Tibubos, A. N., Reiner, I., Brahler, E., Wiltink, J., Michal, M., Nagler, M., Wild, P. S., Munzel, T., Konig, J., Lackner, K. J., Peiffer, N. & Beutel, M. E. Psychol Med, 1-9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35443907  

Assessment of sex- and age-dependency of risk factors for intimal hyperplasia in heart transplant patients using the high resolution of optical coherence tomography. Orban, M., Dietl, M., Dischl, D., von Samson-Himmelstjerna, P., Neubarth-Mayer, J., Struven, A., Tengler, A., Jakob, A., Fischer, M., Rizas, K., Petzold, T., Orban, M., Braun, D., Hausleiter, J., Hagl, C., Haas, N. A., Mehilli, J., Pozza, R. D., Massberg, S. & Ulrich, S. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35447273  

Ablation Lesion Assessment with MRI. Mont, L., Roca-Luque, I. & Althoff, T. F. Arrhythm Electrophysiol Rev 11, e02 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35444808  

Lipopolysaccharide Modifies Sodium Current Kinetics through ROS and PKC Signalling in Induced Pluripotent Stem-Derived Cardiomyocytes from Brugada Syndrome Patient. Liao, Z., Li, Y., Fan, X., Yang, Z., El-Battrawy, I., Zhou, X. & Akin, I. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35448095  

Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis. Liang, G., Wang, S., Shao, J., Jin, Y., Xu, L., Yan, Y., Gunther, S., Wang, L. & Offermanns, S. Circ Res, 101161CIRCRESAHA121320694 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35443807  

NMR Metabolomics Reveal Urine Markers of Microbiome Diversity and Identify Benzoate Metabolism as a Mediator between High Microbial Alpha Diversity and Metabolic Health. Hertel, J., Fassler, D., Heinken, A., Weiss, F. U., Ruhlemann, M., Bang, C., Franke, A., Budde, K., Henning, A. K., Petersmann, A., Volker, U., Volzke, H., Thiele, I., Grabe, H. J., Lerch, M. M., Nauck, M., Friedrich, N. & Frost, F. Metabolites 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35448495  

Treatment of the Aortic Root in Acute Aortic Dissection Type A: Insights from the German Registry for Acute Aortic Dissection Type A (GERAADA) Registry. Kallenbach, K., Busch, C., Rylski, B., Dohle, D. S., Kruger, T., Holubec, T., Brickwedel, J., Poling, J., Noack, T., Hagl, C., Jawny, P., Boning, A., Chalabi, K., Karck, M. & Arif, R. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35441677  

Effects of renin-angiotensin system inhibitor type and dosage on survival after transcatheter aortic valve implantation. Fischer-Rasokat, U., Bansch, C., Renker, M., Rolf, A., Charitos, E. I., Weferling, M., Liebetrau, C., Herrmann, E., Choi, Y. H., Hamm, C. W. & Kim, W. K. Eur Heart J Cardiovasc Pharmacother (2022). https://www.ncbi.nlm.nih.gov/pubmed/35441662  

Movement therapy in lung transplantation candidates assisted by a lightweight wearable robot. Just, I. A., Fries, D., Loewe, S., Falk, V., Cesarovic, N., Kemper, D., Edelmann, F., Feuerstein, A., Haufe, F. L., Xiloyannis, M., Riener, R. & Schoenrath, F. Assist Technol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35438604  

Frontiers in CardioVascular Biomedicine (FCVB) 2022 Budapest is on in person! The excellent programme proves that scientists won against COVID-19. Ferdinandy, P., Koller, Á., Weber, C., Wojta, J. & Waltenberger, J. Cardiovasc Res 118, e59-e61 (2022).

Frontiers of CardioVascular Biomedicine 2022 Budapest is on in person! The excellent program proves that scientists won against Covid-19. Ferdinandy, P., Koller, A., Weber, C., Wojta, J. & Waltenberger, J. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35438746  

Ten-year patterns of stent thrombosis after percutaneous coronary intervention with new- versus early-generation drug-eluting stents: insights from the DECADE cooperation. Coughlan, J. J., Maeng, M., Raber, L., Brugaletta, S., Aytekin, A., Okkels Jensen, L., Bar, S., Ortega-Paz, L., Laugwitz, K. L., Madsen, M., Heg, D., Sabate, M., Kufner, S., Warnakula Olesen, K. K., Kastrati, A., Windecker, S. & Cassese, S. Rev Esp Cardiol (Engl Ed) (2022). https://www.ncbi.nlm.nih.gov/pubmed/35437213  

Machine learning-based identification of risk-factor signatures for undiagnosed atrial fibrillation in primary prevention and post-stroke in clinical practice. Schnabel, R. B., Witt, H., Walker, J., Ludwig, M., Geelhoed, B., Kossack, N., Schild, M., Miller, R. & Kirchhof, P. Eur Heart J Qual Care Clin Outcomes (2022). https://www.ncbi.nlm.nih.gov/pubmed/35436783  

Targeting Cell-Specific Molecular Mechanisms of Innate Immunity in Atherosclerosis. Sauter, M. & Langer, H. F. Front Physiol 13, 802990 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35432000  

Prognostic Power of Pulmonary Arterial Compliance Is Boosted by a Hemodynamic Unloading Test With Glyceryl Trinitrate in Heart Failure Patients With Post-capillary Pulmonary Hypertension. Rieth, A. J., Grun, D., Zarogiannis, G., Kriechbaum, S. D., Wolter, S., Richter, M. J., Tello, K., Kruger, U., Mitrovic, V., Rosenkranz, S., Hamm, C. W. & Keller, T. Front Cardiovasc Med 9, 838898 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35433862  

The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice. Nickel, L., Sunderhauf, A., Rawish, E., Stolting, I., Derer, S., Thorns, C., Matschl, U., Othman, A., Sina, C. & Raasch, W. Front Pharmacol 13, 815353 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35431918  

Micro-dislodgement of a self-expanding transcatheter heart valve: Incidence, predictors, and outcomes. Kim, W. K., Renker, M., Dorr, O., Nef, H., Fischer-Rasokat, U., Choi, Y. H., Hamm, C. W. & Charitos, E. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35436560  

Ruthenaelectro-catalyzed C-H acyloxylation for late-stage tyrosine and oligopeptide diversification. Hou, X., Kaplaneris, N., Yuan, B., Frey, J., Ohyama, T., Messinis, A. M. & Ackermann, L. Chem Sci 13, 3461-3467 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35432858   

Cellular Chitchatting: Exploring the Role of Exosomes as Cardiovascular Risk Factors. Germena, G., Zelarayan, L. C. & Hinkel, R. Front Cell Dev Biol 10, 860005 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35433670  

Transmitral Gradients Following Transcatheter Edge-to-Edge Repair: Are Mean Gradients Meaningful? Hahn, R. T. & Hausleiter, J. JACC Cardiovasc Interv (2022). https://www.ncbi.nlm.nih.gov/pubmed/35430172  

Severe low-gradient aortic stenosis: impact of inadequate left ventricular responses to high afterload on diagnosis and therapeutic decision-making. Dandel, M. & Hetzer, R. Heart Fail Rev (2022). https://www.ncbi.nlm.nih.gov/pubmed/35430696  

Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20. Vieira-Vieira, C. H., Dauksaite, V., Sporbert, A., Gotthardt, M. & Selbach, M. Mol Cell (2022). https://www.ncbi.nlm.nih.gov/pubmed/35427468  

Clinical implications of low estimated protein intake in patients with heart failure. Streng, K. W., Hillege, H. L., Ter Maaten, J. M., van Veldhuisen, D. J., Dickstein, K., Ng, L. L., Samani, N. J., Metra, M., Ponikowski, P., Cleland, J. G., Anker, S. D., Romaine, S. P. R., Damman, K., van der Meer, P., Lang, C. C. & Voors, A. A. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35426256  

Not the classical serendipity: does doxapram treat atrial fibrillation? Liutkute, A., Brundel, B. J. & Voigt, N. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35425974  

Generation of heterozygous (MRli003-A-5) and homozygous (MRli003-A-6) voltage-sensing knock-in human iPSC lines by CRISPR/Cas9 editing of the AAVS1 locus. Zhang, F., Meier, A. B., Sinnecker, D., Engelhardt, S., Lipp, P., Laugwitz, K. L., Dorn, T. & Moretti, A. Stem Cell Res 61, 102785 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35421847  

Symptom burden, psychosocial distress and palliative care needs in heart failure - A cross-sectional explorative pilot study. Strangl, F., Ischanow, E., Ullrich, A., Oechsle, K., Fluschnik, N., Magnussen, C., Knappe, D., Grahn, H., Blankenberg, S., Bokemeyer, C., Kirchhof, P. & Rybczynski, M. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420358  

Surgical Restoration of Antero-Apical Left Ventricular Aneurysms: Cardiac Computed Tomography for Therapy Planning. Solowjowa, N., Nemchyna, O., Hrytsyna, Y., Meyer, A., Hennig, F., Falk, V. & Knosalla, C. Front Cardiovasc Med 9, 763073 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35419444  

Four decades of experience of prosthetic valve endocarditis reflect a high variety of diverse pathogens. Oberbach, A., Schlichting, N., Hagl, C., Lehmann, S., Kullnick, Y., Friedrich, M., Kohl, U., Horn, F., Kumbhari, V., Loffler, B., Schmidt, F., Joskowiak, D., Born, F., Saha, S. & Bagaev, E. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420122  

Prediction of disability-free survival in healthy older people. Neumann, J. T., Thao, L. T. P., Murray, A. M., Callander, E., Carr, P. R., Nelson, M. R., Wolfe, R., Woods, R. L., Reid, C. M., Shah, R. C., Newman, A. B., Williamson, J. D., Tonkin, A. M., McNeil, J. J. & investigators, A. Geroscience 44, 1641-1655 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420334  

Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Melendez, E., Chondronasiou, D., Mosteiro, L., Martinez de Villarreal, J., Fernandez-Alfara, M., Lynch, C. J., Grimm, D., Real, F. X., Alcami, J., Climent, N., Pietrocola, F. & Serrano, M. Development 149 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420133  

Targeting the adipose tissue: heart crosstalk in pressure overload-induced heart failure. Tual-Chalot, S. & Stellos, K. Cardiovasc Res 118, 1854-1856 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35416985  

The Polyscore of autonomic parameters predicts mortality and identifies low-risk individuals among diabetic survivors of acute myocardial infarction. Steger, A., Dommasch, M., Muller, A., Barthel, P., Sinnecker, D., Wieg, L., Hapfelmeier, A., Heidegger, H. H., Huster, K. M., Martens, E., Laugwitz, K. L., Schmidt, G. & Dirschinger, R. Sci Rep 12, 6069 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35414085   

CARMA: what goes around, comes around for the heart. Juni, R. P. & Boon, R. A. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35416964  

Patient related outcomes of mechanical lead extraction techniques (PROMET) study: A comparison of two professions. Akhtar, Z., Gallagher, M. M., Elbatran, A. I., Starck, C. T., Gonzalez, E., Al-Razzo, O., Mazzone, P., Delnoy, P. P., Breitenstein, A., Steffel, J., Eulert-Grehn, J., Lanmuller, P., Melillo, F., Marzi, A., Leung, L. W., Domenichini, G. & Sohal, M. Pacing Clin Electrophysiol 45, 658-665 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35417049  

The Evolution of Complex Muscle Cell In Vitro Models to Study Pathomechanisms and Drug Development of Neuromuscular Disease. Zschuntzsch, J., Meyer, S., Shahriyari, M., Kummer, K., Schmidt, M., Kummer, S. & Tiburcy, M. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35406795

C-Reactive Protein to Albumin Ratio in Patients Undergoing Transcatheter Aortic Valve Replacement. Seoudy, H., Shamekhi, J., Voigtlander, L., Ludwig, S., Frank, J., Kujat, T., Bramlage, P., Al-Kassou, B., Sugiura, A., Rangrez, A. Y., Schofer, N., Puehler, T., Lutter, G., Seiffert, M., Nickenig, G., Conradi, L., Frey, N., Westermann, D., Sinning, J. M. & Frank, D. Mayo Clin Proc 97, 931-940 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35410750  

A High-Protein and Low-Glycemic Formula Diet Improves Blood Pressure and Other Hemodynamic Parameters in High-Risk Individuals. Rohling, M., Kempf, K., Banzer, W., Braumann, K. M., Fuhrer-Sakel, D., Halle, M., McCarthy, D., Martin, S., Scholze, J., Toplak, H., Berg, A., Predel, H. G. & Acoorh Study, G. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35406053  

Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation. Philippe, A., Kleinau, G., Gruner, J. J., Wu, S., Postpieszala, D., Speck, D., Heidecke, H., Dowell, S. J., Riemekasten, G., Hildebrand, P. W., Kamhieh-Milz, J., Catar, R., Szczepek, M., Dragun, D. & Scheerer, P. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35409344  

Interdependence of Angiogenesis and Arteriogenesis in Development and Disease. le Noble, F. & Kupatt, C. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35409246  

Elevation of cardiac biomarkers in stroke is associated with pathological findings on cardiac MRI-results of the HEart and BRain interfaces in Acute Stroke study. von Rennenberg, R., Herm, J., Krause, T., Hellwig, S., Stengl, H., Scheitz, J. F., Elgeti, T., Nagel, S. N., Endres, M., Haeusler, K. G. & Nolte, C. H. Int J Stroke, 17474930221095698 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35403503  

Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets. Freystetter, B., Grab, M., Grefen, L., Bischof, L., Isert, L., Mela, P., Bezuidenhout, D., Hagl, C. & Thierfelder, N. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35404357  

Validity of a multidimensional comprehensive psychosocial screening instrument based on the ESC cardiovascular prevention guidelines - Evidence from the general and cardiovascular patient population. van den Houdt, S., Albus, C., Herrmann-Lingen, C., Widdershoven, J. & Kupper, N. J Psychosom Res 157, 110791 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35398675  

TAVR - From inoperable to younger, lower-risk patients: A slippery slope? Unbehaun, A., Abdullah, M., Hooda, A., Gedela, M., Kempfert, J., Klein, C. & Tang, G. H. L. Prog Cardiovasc Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35398162  

Rapid shear stress-dependent ENaC membrane insertion is mediated by the endothelial glycocalyx and the mineralocorticoid receptor. Cosgun, Z. C., Sternak, M., Fels, B., Bar, A., Kwiatkowski, G., Pacia, M. Z., Herrnbock, L., Lindemann, M., Stegbauer, J., Hoges, S., Chlopicki, S. & Kusche-Vihrog, K. Cell Mol Life Sci 79, 235 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35397686  

Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1. Bauer, A., Puglisi, M., Nagl, D., Schick, J. A., Werner, T., Klingl, A., El Andari, J., Hornung, V., Kessler, H., Gotz, M., Grimm, D. & Brack-Werner, R. Adv Sci (Weinh) 9, e2104979 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35398994  

UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment. Bastian, L., Hartmann, A. M., Beder, T., Hanzelmann, S., Kassens, J., Bultmann, M., Hoeppner, M. P., Franzenburg, S., Wittig, M., Franke, A., Nagel, I., Spielmann, M., Reimer, N., Busch, H., Schwartz, S., Steffen, B., Viardot, A., Dohner, K., Kondakci, M., Wulf, G., Wendelin, K., Renzelmann, A., Kiani, A., Trautmann, H., Neumann, M., Gokbuget, N., Bruggemann, M. & Baldus, C. D. Leukemia 36, 1676-1680 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35397658  

Matched comparison of 3 cerebral perfusion strategies in open zone-0 anastomosis for acute type A aortic dissection. Montagner, M., Kofler, M., Pitts, L., Heck, R., Buz, S., Kurz, S., Falk, V. & Kempfert, J. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35396839  

Generation of two human iPSC lines, HMGUi003-A and MRIi028-A, carrying pathogenic biallelic variants in the PPCS gene. Iuso, A., Zhang, F., Rusha, E., Campbell, B., Dorn, T., Zanuttigh, E., Haas, D., Anikster, Y., Lederer, G., Pertek, A., Nteli, P., Laugwitz, K. L. & Moretti, A. Stem Cell Res 61, 102773 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35397396  

Non-robotic minimally invasive mitral valve repair: a 20-year single-centre experience. Feirer, N., Kornyeva, A., Lang, M., Sideris, K., Voss, B., Krane, M., Lange, R. & Vitanova, K. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35396837  

Pediatric heart transplantation in infants and small children under 3 years of age: Single center experience - "Early and long-term results". Rosenthal, L. L., Ulrich, S. M., Zimmerling, L., Brenner, P., Muller, C., Michel, S., Horer, J., Netz, H., Haas, N. A. & Hagl, C. Int J Cardiol 356, 45-50 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395286  

Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells. Peng, Y., Du, J., Gunther, S., Guo, X., Wang, S., Schneider, A., Zhu, L. & Braun, T. Redox Biol 52, 102309 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395625  

Cardiac remodeling in patients with centrifugal left ventricular assist devices assessed by serial echocardiography. Mulzer, J., Krastev, H., Hoermandinger, C., Merke, N., Alhaloush, M., Schoenrath, F., Falk, V., Potapov, E. & Knierim, J. Echocardiography 39, 667-677 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35393693  

Dysregulated diurnal cortisol patterns are associated with cardiovascular mortality: Findings from the KORA-F3 study. Karl, S., Johar, H., Ladwig, K. H., Peters, A. & Lederbogen, F. Psychoneuroendocrinology 141, 105753 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395560   

Galectin-3 inhibitors as novel antithrombotic drugs with almost no bleeding risk: wishful thinking or a realistic vision? Jakobs, K. & Rauch, U. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35393607  

Transcatheter implantation of covered stents serving as extravascular conduits-Proof of a CT-based approach in three cases. Ewert, P., Eicken, A., Tanase, D., Georgiev, S., Will, A., Pankalla, C., Nagdyman, N., Meierhofer, C. & Horer, J. Catheter Cardiovasc Interv 99, 2054-2063 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395135  

Pharmacological Targeting of the CCL2/CCR2 Axis for Atheroprotection: A Meta-Analysis of Preclinical Studies. Zivkovic, L., Asare, Y., Bernhagen, J., Dichgans, M. & Georgakis, M. K. Arterioscler Thromb Vasc Biol 42, e131-e144 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35387476  

Biomarker changes as surrogate endpoints in early-phase trials in heart failure with reduced ejection fraction. Savarese, G., Uijl, A., Ouwerkerk, W., Tromp, J., Anker, S. D., Dickstein, K., Hage, C., Lam, C. S. P., Lang, C. C., Metra, M., Ng, L. L., Orsini, N., Samani, N. J., van Veldhuisen, D. J., Cleland, J. G. F., Voors, A. A. & Lund, L. H. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35388650  

Endocrine and molecular factors of increased female reproductive performance in the Dummerstorf high-fertility mouse line FL1. Ludwig, C. L. M., Bohleber, S., Rebl, A., Wirth, E. K., Venuto, M. T., Langhammer, M., Schweizer, U., Weitzel, J. M. & Michaelis, M. J Mol Endocrinol 69, 285-298 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35388794  

Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation - A proof-of-concept study. Jebran, A. F., Tiburcy, M., Biermann, D., Balfanz, P., Didie, M., Karikkineth, B. C., Schondube, F., Kutschka, I. & Zimmermann, W. H. J Mol Cell Cardiol 168, 3-12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35390437   

A Family and a Genome-Wide Polygenic Risk Score Are Independently Associated With Stroke in a Population-Based Study. Hammerle, M., Forer, L., Schonherr, S., Peters, A., Grallert, H., Kronenberg, F., Gieger, C. & Lamina, C. Stroke 53, 2331-2339 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35387493  

Cardio-oncology imaging tools at the translational interface. Yaros, K., Eksi, B., Chandra, A., Agusala, K., Lehmann, L. H. & Zaha, V. G. J Mol Cell Cardiol 168, 24-32 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35385715  

Attentive follow-up to counter alarmism. Twerenbold, R., Cavus, E. & Blankenberg, S. Eur Heart J 43, 1994 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35383357  

ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. Rohlfing, A. K., Kolb, K., Sigle, M., Ziegler, M., Bild, A., Munzer, P., Sudmann, J., Dicenta, V., Harm, T., Manke, M. C., Geue, S., Kremser, M., Chatterjee, M., Liang, C., von Eysmondt, H., Dandekar, T., Heinzmann, D., Gunter, M., von Ungern-Sternberg, S., Buttcher, M., Castor, T., Mencl, S., Langhauser, F., Sies, K., Ashour, D., Beker, M. C., Lammerhofer, M., Autenrieth, S. E., Schaffer, T. E., Laufer, S., Szklanna, P., Maguire, P., Heikenwalder, M., Muller, K. A. L., Hermann, D. M., Kilic, E., Stumm, R., Ramos, G., Kleinschnitz, C., Borst, O., Langer, H. F., Rath, D. & Gawaz, M. Nat Commun 13, 1823 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35383158  

New ESC/EACTS guideline recommendations for the treatment of secondary mitral regurgitation: reflections on the evidence. Frerker, C., Karam, N., Hahn, R. T., Thiele, H., Stone, G. W., Treede, H. & Hausleiter, J. Eur J Heart Fail 24, 746-749 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35385192  

Adverse events and stroke prevention by interventional left atrial appendage occlusion in patients with low CHA2 DS2 -VASc score-results from the multicenter German LAARGE registry. Fastner, C., Brachmann, J., Lewalter, T., Zeymer, U., Sievert, H., Ledwoch, J., Geist, V., Hochadel, M., Schneider, S., Senges, J., Akin, I. & Ansari, U. Catheter Cardiovasc Interv 99, 2064-2070 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35384249  

The everlasting challenge to identify deep vein thrombosis in both clinical practice and research. Behrendt, C. A., Twerenbold, R. & Blankenberg, S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35383353  

Clinical implementation of RNA sequencing for Mendelian disease diagnostics. Yepez, V. A., Gusic, M., Kopajtich, R., Mertes, C., Smith, N. H., Alston, C. L., Ban, R., Beblo, S., Berutti, R., Blessing, H., Ciara, E., Distelmaier, F., Freisinger, P., Haberle, J., Hayflick, S. J., Hempel, M., Itkis, Y. S., Kishita, Y., Klopstock, T., Krylova, T. D., Lamperti, C., Lenz, D., Makowski, C., Mosegaard, S., Muller, M. F., Munoz-Pujol, G., Nadel, A., Ohtake, A., Okazaki, Y., Procopio, E., Schwarzmayr, T., Smet, J., Staufner, C., Stenton, S. L., Strom, T. M., Terrile, C., Tort, F., Van Coster, R., Vanlander, A., Wagner, M., Xu, M., Fang, F., Ghezzi, D., Mayr, J. A., Piekutowska-Abramczuk, D., Ribes, A., Rotig, A., Taylor, R. W., Wortmann, S. B., Murayama, K., Meitinger, T., Gagneur, J. & Prokisch, H. Genome Med 14, 38 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35379322   

Effects of caloric restriction on the gut microbiome are linked with immune senescence. Sbierski-Kind, J., Grenkowitz, S., Schlickeiser, S., Sandforth, A., Friedrich, M., Kunkel, D., Glauben, R., Brachs, S., Mai, K., Thurmer, A., Radonic, A., Drechsel, O., Turnbaugh, P. J., Bisanz, J. E., Volk, H. D., Spranger, J. & von Schwartzenberg, R. J. Microbiome 10, 57 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35379337  

Analytical interference of 33 different hemoglobin variants on HbA1c measurements comparing high-performance liquid chromatography with whole blood enzymatic assay: A multi-center study. Zechmeister, B., Erden, T., Kreutzig, B., Weber, M., Joly, P., Erdmann, J., Brockmann-Honig, C., Fischer, A. & Eidizadeh, A. Clin Chim Acta 531, 145-151 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35378091  

Transcatheter aortic valve-in-valve implantation under cerebral protection in a patient with a deteriorated 19-mm rapid-deployment bioprosthetic valve. Van Praet, K. M., Nersesian, G., Kukucka, M., Heil, E., Kofler, M., Falk, V., Klein, C., Kempfert, J. & Unbehaun, A. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35377972  

Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction. Cornean, A., Gierten, J., Welz, B., Mateo, J. L., Thumberger, T. & Wittbrodt, J. Elife 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35373735  

Selective optogenetic control of Gq signaling using human Neuropsin. Wagdi, A., Malan, D., Sathyanarayanan, U., Beauchamp, J. S., Vogt, M., Zipf, D., Beiert, T., Mansuroglu, B., Dusend, V., Meininghaus, M., Schneider, L., Kalthof, B., Wiegert, J. S., Konig, G. M., Kostenis, E., Patejdl, R., Sasse, P. & Bruegmann, T. Nat Commun 13, 1765 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35365606  

Computed tomography predictors of structural valve degeneration in patients undergoing transcatheter aortic valve implantation with balloon-expandable prostheses. Guglielmo, M., Fusini, L., Muratori, M., Tamborini, G., Mantegazza, V., Andreini, D., Annoni, A., Babbaro, M., Baggiano, A., Conte, E., Carriero, S., Formenti, A., Guaricci, A. I., Mancini, E., Mollace, R., Muscogiuri, G., Mushtaq, S., Ricci, F., Rossi, A., Scafuri, S., Alushi, B., Cau, C., Cau, R., Cesarano, M., Saba, L., Rabbat, M., Pepi, M. & Pontone, G. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35364711  

Partial ring annuloplasty in the management of mitral annular calcification. Akansel, S., Kofler, M., Sundermann, S. H., Van Praet, K. M., Falk, V. & Kempfert, J. J Card Surg 37, 1749-1752 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35366352  

Cardiac disease and prognosis associated with ventricular tachyarrhythmias in young adults and adults. Weidner, K., Behnes, M., Schupp, T., Hoppner, J., El-Battrawy, I., Ansari, U., Saleh, A., Taton, G., Reiser, L., Bollow, A., Reichelt, T., Ellguth, D., Engelke, N., Bertsch, T., Grosse Meininghaus, D., Hoffmann, U. & Akin, I. BMC Cardiovasc Disord 22, 136 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361107  

High resolution optical mapping of cardiac electrophysiology in pre-clinical models. O'Shea, C., Winter, J., Kabir, S. N., O'Reilly, M., Wells, S. P., Baines, O., Sommerfeld, L. C., Correia, J., Lei, M., Kirchhof, P., Holmes, A. P., Fabritz, L., Rajpoot, K. & Pavlovic, D. Sci Data 9, 135 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361792  

An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form. Menon, P. R., Staab, J., Gregus, A., Wirths, O. & Meyer, T. Cell Commun Signal 20, 42 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361236  

Frailty, Guideline-Directed Medical Therapy, and Outcomes in HFrEF: From the GUIDE-IT Trial. Khan, M. S., Segar, M. W., Usman, M. S., Singh, S., Greene, S. J., Fonarow, G. C., Anker, S. D., Felker, G. M., Januzzi, J. L., Jr., Butler, J. & Pandey, A. JACC Heart Fail 10, 266-275 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361446  

Comparison of American and European Guidelines for Primary Prevention of Cardiovascular Disease: JACC Guideline Comparison. Fegers-Wustrow, I., Gianos, E., Halle, M. & Yang, E. J Am Coll Cardiol 79, 1304-1313 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361353  

Surgical treatment of tricuspid valve dysplasia in children. Cleuziou, J., Pringsheim, M., Stroh, A., Burri, M., Lange, R. & Horer, J. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35362523  

Synthetic Extracellular Volume in Cardiac Magnetic Resonance Without Blood Sampling: a Reliable Tool to Replace Conventional Extracellular Volume. Chen, W., Doeblin, P., Al-Tabatabaee, S., Klingel, K., Tanacli, R., Jakob Weiss, K., Stehning, C., Patel, A. R., Pieske, B., Zou, J. & Kelle, S. Circ Cardiovasc Imaging 15, e013745 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360924  

Impact of machine-learning-based coronary computed tomography angiography-derived fractional flow reserve on decision-making in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. Brandt, V., Schoepf, U. J., Aquino, G. J., Bekeredjian, R., Varga-Szemes, A., Emrich, T., Bayer, R. R., 2nd, Schwarz, F., Kroencke, T. J., Tesche, C. & Decker, J. A. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35359166  

Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Malacarne, P. F., Ratiu, C., Gajos-Draus, A., Muller, N., Lopez, M., Pfluger-Muller, B., Ding, X., Warwick, T., Oo, J., Siragusa, M., Angioni, C., Gunther, S., Weigert, A., Geisslinger, G., Lutjohann, D., Schunck, W. H., Fleming, I., Brandes, R. P. & Rezende, F. Hypertension 79, 1216-1226 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35354305  

Serum starvation induces sexual dimorphisms in secreted proteins of human umbilical vein endothelial cells (HUVECs) from twin pairs. Lorenz, M., Witt, E., Volker, U., Stangl, K., Stangl, V. & Hammer, E. Proteomics, e2100168 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35357760  

Comparison of transient and permanent LAD ligation in mice using 18F-FDG PET imaging. Fischer, M., Weinberger, T., Messerer, D., Zacherl, M. J., Schulz, C., Massberg, S., Bartenstein, P., Lehner, S., Boening, G. & Todica, A. Ann Nucl Med 36, 533-543 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35355159


März

 

Multicenter comparison of latest-generation balloon-expandable versus self-expanding transcatheter heart valves: Ultra versus Evolut. Rheude, T., Pellegrini, C., Allali, A., Bleiziffer, S., Kim, W. K., Neuser, J., Landt, M., Rudolph, T., Renker, M., Widder, J. D., Qu, L., Alvarez-Covarrubias, H. A., Mayr, N. P., Richardt, G., Xhepa, E. & Joner, M. Int J Cardiol 357, 115-120 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35337936   

Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects. Dyck, J. R. B., Sossalla, S., Hamdani, N., Coronel, R., Weber, N. C., Light, P. E. & Zuurbier, C. J. J Mol Cell Cardiol 167, 17-31 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35331696

P2Y12-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction. Seung, H., Wrobel, J., Wadle, C., Buhler, T., Chiang, D., Rettkowski, J., Cabezas-Wallscheid, N., Hechler, B., Stachon, P., Maier, A., Weber, C., Wolf, D., Duerschmied, D., Idzko, M., Bode, C., von Zur Muhlen, C., Hilgendorf, I. & Heidt, T. Basic Res Cardiol 117, 16 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35353230  

Comparison of cardiac volumetry using real-time MRI during free-breathing with standard cine MRI during breath-hold in children. Rower, L. M., Radke, K. L., Hussmann, J., Malik, H., Uelwer, T., Voit, D., Frahm, J., Wittsack, H. J., Harmeling, S., Pillekamp, F. & Klee, D. Pediatr Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35353211  

Increased cardiovascular risk in boys born with hypospadias: intriguing observations and remaining questions. Krankel, N. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35352117  

Detection of cardiac apoptosis by [(18)F]ML-10 in a mouse model of permanent LAD ligation. Fischer, M., Olivier, J., Lindner, S., Zacherl, M. J., Massberg, S., Bartenstein, P., Ziegler, S., Brendel, M., Lehner, S., Boening, G. & Todica, A. Mol Imaging Biol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35352214  

Hemodynamic Effects of Sacubitril/Valsartan in Patients with Reduced Left Ventricular Ejection Fraction Over 24 Months: A Retrospective Study. Abumayyaleh, M., Demmer, J., Krack, C., Pilsinger, C., El-Battrawy, I., Behnes, M., Aweimer, A., Mugge, A., Lang, S. & Akin, I. Am J Cardiovasc Drugs (2022). https://www.ncbi.nlm.nih.gov/pubmed/35353351  

Cohort Profile Update: The Study of Health in Pomerania (SHIP). Volzke, H., Schossow, J., Schmidt, C. O., Jurgens, C., Richter, A., Werner, A., Werner, N., Radke, D., Teumer, A., Ittermann, T., Schauer, B., Henck, V., Friedrich, N., Hannemann, A., Winter, T., Nauck, M., Dorr, M., Bahls, M., Felix, S. B., Stubbe, B. et al. Int J Epidemiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35348705  

Long-term impact of the metabolic status on weight loss-induced health benefits. Soll, D., Gawron, J., Pletsch-Borba, L., Spranger, J. & Mai, K. Nutr Metab (Lond) 19, 25 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35346256  

[Long-term course of heart disease: How can psychosocial care be improved?]. Ladwig, K. H., Lurz, J. & Lukaschek, K. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65, 481-487 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35347347  

Feasibility, Acceptability, and Preliminary Efficacy of a Positive Psychology Intervention in Patients With Coronary Heart Disease: A Randomized Controlled Trial. Sadlonova, M., Kermani, M. B., Huffman, J. C., Nikrahan, G. R., Sadeghi, M. & Celano, C. M. J Acad Consult Liaison Psychiatry (2022). https://www.ncbi.nlm.nih.gov/pubmed/35342036  

[Analytical Quality of Glucose Measurements in Germany]. Freckmann, G., Heinemann, L., Pleus, S., Petersmann, A., Kaiser, P. & Nauck, M. Dtsch Med Wochenschr 147, 407-413 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35345048  

Transcatheter mitral valve implantation in the ongoing structural heart revolution. Sa, M. P., Ramlawi, B., Gray, W. A., Malin, J. H., Van den Eynde, J., Sicouri, S., Torregrossa, G., Klein, C., Heil, E., Sundermann, S. H., Emmerich, A., Kempfert, J., Kofler, M., Falk, V., Unbehaun, A. & Van Praet, K. M. J Card Surg 37, 1691-1704 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35340080   

COVID-19-associated cardiac pathology at post-mortem evaluation: A Collaborative systematic Review. Almamlouk, R., Kashour, T., Obeidat, S., Bois, M. C., Maleszewski, J. J., Omrani, O. A., Tleyjeh, R., Berbari, E., Chakhachiro, Z., Zein-Sabatto, B., Gerberi, D., Tleyjeh, I. M. & Cardiac Autopsy in, C.-S. G. Clin Microbiol Infect (2022). https://www.ncbi.nlm.nih.gov/pubmed/35339672  

Characteristics and outcomes of patients screened for transcatheter mitral valve implantation: 1-year results from the CHOICE-MI registry. Ben Ali, W., Ludwig, S., Duncan, A., Weimann, J., Nickenig, G., Tanaka, T., Coisne, A., Vincentelli, A., Makkar, R., Webb, J. G., Akodad, M., Muller, D. W. M., Praz, F., Wild, M. G., Hausleiter, J., Goel, S. S., von Ballmoos, M. W., Denti, P., Chehab, O., Redwood, S. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35338542  

Effects of Apolipoprotein E polymorphism on carotid intima-media thickness, incident myocardial infarction and incident stroke. Pitchika, A., Markus, M. R. P., Schipf, S., Teumer, A., Van der Auwera, S., Nauck, M., Dorr, M., Felix, S., Grabe, H. J., Volzke, H. & Ittermann, T. Sci Rep 12, 5142 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35332187  

Fractal analysis of 4D dynamic myocardial stress-CT perfusion imaging differentiates micro- and macrovascular ischemia in a multi-center proof-of-concept study. Michallek, F., Nakamura, S., Ota, H., Ogawa, R., Shizuka, T., Nakashima, H., Wang, Y. N., Ito, T., Sakuma, H., Dewey, M. & Kitagawa, K. Sci Rep 12, 5085 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35332236  

Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice. Jensen, M., Muller, C., Hubner, N., Patone, G., Saar, K., Choe, C. U., Schwedhelm, E. & Zeller, T. Sci Rep 12, 5108 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35332188  

Cardiac remodelling - Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology. Gonzalez, A., Richards, A. M., de Boer, R. A., Thum, T., Arfsten, H., Hulsmann, M., Falcao-Pires, I., Diez, J., Foo, R. S. Y., Chan, M. Y., Aimo, A., Anene-Nzelu, C. G., Abdelhamid, M., Adamopoulos, S., Anker, S. D., Belenkov, Y., Gal, T. B., Cohen-Solal, A., Bohm, M., Chioncel, O. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35334137  

Responder analysis for improvement in 6-min walk test with ferric carboxymaltose in patients with heart failure with reduced ejection fraction and iron deficiency. Anker, S. D., Ponikowski, P., Khan, M. S., Friede, T., Jankowska, E. A., Fabien, V., Goehring, U. M., Metra, M., Pina, I. L., Coats, A. J. S., Rosano, G., Dorigotti, F., Comin-Colet, J., Van Veldhuisen, D. J., Filippatos, G. S. & Butler, J. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35334136  

Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor. Warwick, T., Schulz, M. H., Gilsbach, R., Brandes, R. P. & Seuter, S. Nucleic Acids Res 50, 3745-3763 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35325193  

Risk-related short-term clinical outcomes after transcatheter aortic valve implantation and their impact on early mortality: an analysis of claims-based data from Germany. Schofer, N., Jeschke, E., Kroger, J., Baberg, H., Falk, V., Gummert, J. F., Hamm, C. W., Mockel, M., Gossling, A., Malzahn, J., Gunster, C. & Blankenberg, S. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35325270  

Brugada Syndrome: Different Experimental Models and the Role of Human Cardiomyocytes From Induced Pluripotent Stem Cells. Li, Y., Lang, S., Akin, I., Zhou, X. & El-Battrawy, I. J Am Heart Assoc 11, e024410 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35322667  

Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts premature death in acute coronary syndromes. Kraler, S., Wenzl, F. A., Georgiopoulos, G., Obeid, S., Liberale, L., von Eckardstein, A., Muller, O., Mach, F., Raber, L., Losdat, S., Schmiady, M. O., Stellos, K., Stamatelopoulos, K., Camici, G. G., Srdic, A., Paneni, F., Akhmedov, A. & Luscher, T. F. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35325132  

Risk Factors, Subsequent Disease Onset, and Prognostic Impact of Myocardial Infarction and Atrial Fibrillation. Camen, S., Csengeri, D., Geelhoed, B., Niiranen, T., Gianfagna, F., Vishram-Nielsen, J. K., Costanzo, S., Soderberg, S., Vartiainen, E., Borschel, C. S., Donati, M. B., Lochen, M. L., Ojeda, F. M., Kontto, J., Mathiesen, E. B., Jensen, S., Koenig, W., Kee, F., de Gaetano, G., Zeller, T. et al. J Am Heart Assoc 11, e024299 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35322680  

Weight loss did not modify macronutrient specific response of hormones and satiety in overweight and obese people without metabolic disease - results from a clinical trial. Li, L., Decker, A. M., Stobaus, N., Beer, F., Grittner, U., Spranger, J. & Mai, K. Clin Nutr 41, 948-957 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35303516  

Predicting visceral adipose tissue in older adults: A pilot clinical study. Perna, S., Faragli, A., Spadaccini, D., Peroni, G., Gasparri, C., Al-Mannai, M. A., Casali, P. M., La Porta, E., Kelle, S., Alogna, A. & Rondanelli, M. Clin Nutr 41, 810-816 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35263690  

 

 

Role of Reticulated Platelets in Cardiovascular Disease. Bongiovanni, D., Han, J., Klug, M., Kirmes, K., Viggiani, G., von Scheidt, M., Schreiner, N., Condorelli, G., Laugwitz, K. L. & Bernlochner, I. Arterioscler Thromb Vasc Biol, ATVBAHA121316244 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35321562  

TAVI in patients with low-flow low-gradient aortic stenosis-short-term and long-term outcomes. Steffen, J., Reissig, N., Andreae, D., Beckmann, M., Haum, M., Fischer, J., Theiss, H., Braun, D., Orban, M., Rizas, K., Sadoni, S., Nabauer, M., Peterss, S., Hausleiter, J., Massberg, S. & Deseive, S. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35320407  

Progressive machine-based resistance training for prevention and treatment of sarcopenia in the oldest old: A systematic review and meta-analysis. Mende, E., Moeinnia, N., Schaller, N., Weiss, M., Haller, B., Halle, M. & Siegrist, M. Exp Gerontol, 111767 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35318104   

Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study. Just, I. A., Fries, D., Loewe, S., Falk, V., Cesarovic, N., Edelmann, F., Feuerstein, A., Haufe, F. L., Xiloyannis, M., Riener, R. & Schoenrath, F. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35320878  

Sample size calculation for the augmented logrank test in randomized clinical trials. Hattori, S., Komukai, S. & Friede, T. Stat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35319100  

Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS). Haffke, M., Freitag, H., Rudolf, G., Seifert, M., Doehner, W., Scherbakov, N., Hanitsch, L., Wittke, K., Bauer, S., Konietschke, F., Paul, F., Bellmann-Strobl, J., Kedor, C., Scheibenbogen, C. & Sotzny, F. J Transl Med 20, 138 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35317812  

Challenges in the conduct of randomised controlled trials in cardiogenic shock complicating acute myocardial infarction. Freund, A., Desch, S. & Thiele, H. J Geriatr Cardiol 19, 125-129 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35317398  

In vivo and ex vivo electrophysiological study of the mouse heart to characterize the cardiac conduction system, including atrial and ventricular vulnerability. Hennis, K., Rotzer, R. D., Rilling, J., Wu, Y., Thalhammer, S. B., Biel, M., Wahl-Schott, C. & Fenske, S. Nat Protoc (2022). https://www.ncbi.nlm.nih.gov/pubmed/35314849  

Different activation of MAPKs and Akt/GSK3beta after preload vs. afterload elevation. Hartmann, N., Preuss, L., Mohamed, B. A., Schnelle, M., Renner, A., Hasenfuss, G. & Toischer, K. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35315235  

Empagliflozin in patients with type 2 diabetes mellitus and chronic obstructive pulmonary disease. Anker, S. D., Sander, L. E., Fitchett, D. H., Zinman, B., Pernille Ofstad, A., Wanner, C., Vedin, O., Lauer, S., Verma, S., Yaggi, H. K. & Inzucchi, S. E. Diabetes Res Clin Pract, 109837 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35314257  

The Role of Glutamine and Glutaminase in Pulmonary Hypertension. Wang, S., Yan, Y., Xu, W. J., Gong, S. G., Zhong, X. J., An, Q. Y., Zhao, Y. L., Liu, J. M., Wang, L., Yuan, P. & Jiang, R. Front Cardiovasc Med 9, 838657 (2022).

Platelets, Thromboinflammation and Neurovascular Disease. Sun, Y. & Langer, H. F. Front Immunol 13, 843404 (2022).

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats. Sang, P., Kucherenko, M. M., Yao, J., Li, Q., Simmons, S., Kuebler, W. M. & Knosalla, C. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35311828  

Targeting platelet-derived CXCL12 impedes arterial thrombosis. Leberzammer, J., Agten, S. M., Blanchet, X., Duan, R., Ippel, H., Megens, R. T. A., Schulz, C., Aslani, M., Duchene, J., Doring, Y., Jooss, N. J., Zhang, P., Brandl, R., Stark, K., Siess, W., Jurk, K., Heemskerk, J. W. M., Hackeng, T. M., Mayo, K. H., Weber, C. et al. Blood (2022). https://www.ncbi.nlm.nih.gov/pubmed/35313337   

Coronary artery disease, left ventricular function and cardiac biomarkers determine all-cause mortality in cancer patients-a large monocenter cohort study. Finke, D., Heckmann, M. B., Wilhelm, S., Entenmann, L., Hund, H., Bougatf, N., Katus, H. A., Frey, N. & Lehmann, L. H. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35312818  

Stroke after transcatheter aortic valve replacement: A severe complication with low predictability. Eschenbach, L. K., Erlebach, M., Deutsch, M. A., Ruge, H., Bleiziffer, S., Holzer, L., Krane, M., Voss, S., Lange, R. & Burri, M. Catheter Cardiovasc Interv (2022). https://www.ncbi.nlm.nih.gov/pubmed/35312220  

Svep1 stabilises developmental vascular anastomosis in reduced flow conditions. Coxam, B., Collins, R. T., Hussmann, M., Huisman, Y., Meier, K., Jung, S., Bartels-Klein, E., Szymborska, A., Finotto, L., Helker, C. S. M., Stainier, D. Y. R., Schulte-Merker, S. & Gerhardt, H. Development 149 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35312765  

Genetically determined reproductive aging and coronary heart disease: a bidirectional two-sample Mendelian Randomization. Dam, V., Onland-Moret, N. C., Burgess, S., Chirlaque, M. D., Peters, S. A. E., Schuit, E., Tikk, K., Weiderpass, E., Oliver-Williams, C., Wood, A. M., Tjonneland, A., Dahm, C. C., Overvad, K., Boutron-Ruault, M. C., Schulze, M. B., Trichopoulou, A., Ferrari, P., Masala, G., Krogh, V., Tumino, R. et al. J Clin Endocrinol Metab (2022). https://www.ncbi.nlm.nih.gov/pubmed/35306566  

Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE". Seidel, F., Opgen-Rhein, B., Rentzsch, A., Boehne, M., Wannenmacher, B., Boecker, D., Reineker, K., Grafmann, M., Wiegand, G., Hecht, T., Kiski, D., Fischer, M., Papakostas, K., Ruf, B., Kramp, J., Khalil, M., Kaestner, M., Steinmetz, M., Fischer, G., Ozcan, S. et al. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304189  

Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Santovito, D. & Weber, C. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304600  

Does social support prevent suicidal ideation in women and men? Gender-sensitive analyses of an important protective factor within prospective community cohorts. Otten, D., Ernst, M., Tibubos, A. N., Brahler, E., Fleischer, T., Schomerus, G., Wild, P. S., Zoller, D., Binder, H., Kruse, J., Johar, H., Atasoy, S., Grabe, H. J., Ladwig, K. H., Munzel, T., Volzke, H., Konig, J. & Beutel, M. E. J Affect Disord 306, 157-166 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304236  

Single-centre outcome of extracorporeal membrane oxygenation after the neonatal Norwood procedure. Mayr, B., Kido, T., Holder, S., Wallner, M., Vodiskar, J., Strbad, M., Ruf, B., Hager, A., Ewert, P., Horer, J., Lange, R. & Ono, M. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304610  

Sudden cardiac death while waiting: do we need the wearable cardioverter-defibrillator? Israel, C., Staudacher, I., Leclercq, C., Botto, G. L., Scherr, D., Fach, A., Duru, F., Zylla, M. M., Katus, H. A. & Thomas, D. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35305126  

MicroRNAs Regulate TASK-1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation. Wiedmann, F., Kraft, M., Kallenberger, S., Buscher, A., Paasche, A., Blochberger, P. L., Seeger, T., Javorszky, N., Warnecke, G., Arif, R., Kremer, J., Karck, M., Frey, N. & Schmidt, C. J Am Heart Assoc, e023472 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35301863  

Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus-specific. Muehleman, D. L., Crocini, C., Swearingen, A. R., Ozeroff, C. D. & Leinwand, L. A. Am J Physiol Heart Circ Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35302880  

Impact of Right Ventricular Pressure Load After Repair of Tetralogy of Fallot. Latus, H., Stammermann, J., Voges, I., Waschulzik, B., Gutberlet, M., Diller, G. P., Schranz, D., Ewert, P., Beerbaum, P., Kuhne, T., Sarikouch, S. & German Competence Network for Congenital Heart Defects Investigators. J Am Heart Assoc, e022694 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35301850  

The normalized slope conductance as a tool for quantitative analysis of current-voltage relations. Hermann, C., Treder, A., Naher, M., Geiseler, R., Gudermann, T., Mederos, Y. S. M. & Storch, U. Biophys J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35300969  

Association of MRI-based adrenal gland volume and impaired glucose metabolism in a population-based cohort study. Askani, E., Rospleszcz, S., Lorbeer, R., Kulka, C., von Kruchten, R., Muller-Peltzer, K., Hasic, D., Kellner, E., Reisert, M., Rathmann, W., Peters, A., Schlett, C. L., Bamberg, F. & Storz, C. Diabetes Metab Res Rev, e3528 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35303389  

Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and skeletal muscle contractility. Adams, V., Schauer, A., Augstein, A., Kirchhoff, V., Draskowski, R., Jannasch, A., Goto, K., Lyall, G., Mannel, A., Barthel, P., Mangner, N., Winzer, E. B., Linke, A. & Labeit, S. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35301823  

Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets. Wolf, R., Grammbauer, S., Palankar, R., Tolksdorf, C., Moritz, E., Bohm, A., Hasan, M., Hafkemeyer, A., Greinacher, A., Tzvetkov, M. V., Rauch, B. H. & Jedlitschky, G. Haematologica (2022). https://www.ncbi.nlm.nih.gov/pubmed/35295075  

A systematic review and meta-analysis of the cerebrovascular event incidence after transcatheter aortic valve implantation. Meertens, M. M., Macherey, S., Asselberghs, S., Lee, S., Schipper, J. H., Mees, B., Eitel, I., Baldus, S., Frerker, C. & Schmidt, T. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35298700  

TAVR or SAVR? What can we learn from a pooled meta-analysis of reconstructed time to event data? Lange, R., Vitanova, K. & Ruge, H. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35298634  

Dronedarone for the Treatment of Atrial Fibrillation with Concomitant Heart Failure with Preserved and Mildly Reduced Ejection Fraction: Post-Hoc Analysis of the ATHENA Trial. Vaduganathan, M., Piccini, J. P., Camm, A. J., Crijns, H., Anker, S. D., Butler, J., Stewart, J., Braceras, R., Albuquerque, A. P., Wieloch, M. & Hohnloser, S. H. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35293087  

Simultaneous assessment of spontaneous cage activity and voluntary wheel running in group-housed mice. Reuser, A., Wenzel, K., Felix, S. B., Dorr, M., Bahls, M. & Konemann, S. Sci Rep 12, 4444 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35292692  

Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure. Pagnesi, M., Adamo, M., Sama, I. E., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., Inciardi, R. M., Lang, C. C., Lombardi, C. M., Ng, L. L., Ponikowski, P., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Voors, A. A. & Metra, M. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35294624  

Mind and body interventions in cardiology : The importance of the brain-heart connection. Lurz, J. & Ladwig, K. H. Herz 47, 103-109 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35292838  

A system for real-time multivariate feature combination of endoscopic mitral valve simulator training data. Fuchs, R., Van Praet, K. M., Bieck, R., Kempfert, J., Holzhey, D., Kofler, M., Borger, M. A., Jacobs, S., Falk, V. & Neumuth, T. Int J Comput Assist Radiol Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35294716  

The epigenetic enzyme DOT1L orchestrates vascular smooth muscle cell-monocyte crosstalk and protects against atherosclerosis via the NF-kappaB pathway. Farina, F. M., Serio, S., Hall, I. F., Zani, S., Cassanmagnago, G. A., Climent, M., Civilini, E., Condorelli, G., Quintavalle, M. & Elia, L. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35292818  

Heart-Type Fatty Acid Binding Protein, Cardiovascular Outcomes, and Death: Findings From the German CKD Cohort Study. Schneider, M. P., Schmid, M., Nadal, J., Wanner, C., Krane, V., Floege, J., Saritas, T., Busch, M., Sitter, T., Friedrich, N., Stockmann, H., Meiselbach, H., Nauck, M., Kronenberg, F., Eckardt, K. U. & Investigators, G. S. Am J Kidney Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35288215  

Determination of scar area using native and post-contrast T1 mapping: Agreement with late gadolinium enhancement. Kolentinis, M., Carerj, L. M., Vidalakis, E., Giokoglu, E., Martin, S., Arendt, C., Vogl, T. J., Nagel, E. & Puntmann, V. O. Eur J Radiol 150, 110242 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35290909  

CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver. Kaltenbacher, T., Loprich, J., Maresch, R., Weber, J., Muller, S., Oellinger, R., Gross, N., Griger, J., de Andrade Kratzig, N., Avramopoulos, P., Ramanujam, D., Brummer, S., Widholz, S. A., Barthel, S., Falcomata, C., Pfaus, A., Alnatsha, A., Mayerle, J., Schmidt-Supprian, M., Reichert, M. et al. Nat Protoc (2022). https://www.ncbi.nlm.nih.gov/pubmed/35288718  

Plasma circulating micro-RNAs associated with alexithymia reflect a high overlap on neuropsychiatric outcomes. Van der Auwera, S., Ameling, S., Nauck, M., Volzke, H., Volker, U. & Grabe, H. J. J Affect Disord 305, 206-212 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35283179  

Recommendations in pre-procedural imaging assessment for transcatheter aortic valve implantation intervention: Italian Society of Cardiology (SIC)-Italian Society of Medical and Interventional Radiology (SIRM) position paper part 1 (Clinical Indication and Basic Technical Aspects, Heart Team, Role of Echocardiography). Pontone, G., Marano, R., Agricola, E., Alushi, B., Bartorelli, A., Cameli, M., Carrabba, N., Esposito, A., Faletti, R., Francone, M., Galea, N., Golino, P., Guglielmo, M., Palmisano, A., Petronio, S., Petulla, M., Pradella, S., Ribichini, F., Romeo, F., Russo, V. et al. J Cardiovasc Med (Hagerstown) 23, 216-227 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35287156  

Association between hepatic iron overload assessed by magnetic resonance imaging and glucose intolerance states in the general population. Naeem, M., Schipf, S., Bulow, R., Werner, N., Dorr, M., Lerch, M. M., Kuhn, J. P., Rathmann, W., Nauck, M., Paulista Markus, M. R., Targher, G., Ittermann, T. & Volzke, H. Nutr Metab Cardiovasc Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35282980  

Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy. Kaur, N., Ruiz-Velasco, A., Raja, R., Howell, G., Miller, J. M., Abouleisa, R. R. E., Ou, Q., Mace, K., Hille, S. S., Frey, N., Binder, P., Smith, C. P., Fachim, H., Soran, H., Swanton, E., Mohamed, T. M. A., Muller, O. J., Wang, X., Chernoff, J., Cartwright, E. J. et al. iScience 25, 103973 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35281739  

Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication. Froese, N., Cordero, J., Abouissa, A., Trogisch, F. A., Grein, S., Szaroszyk, M., Wang, Y., Gigina, A., Korf-Klingebiel, M., Bosnjak, B., Davenport, C. F., Wiehlmann, L., Geffers, R., Riechert, E., Jurgensen, L., Boileau, E., Lin, Y., Dieterich, C., Forster, R., Bauersachs, J. et al. iScience 25, 103965 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35281736  

Chronic isoprenaline/phenylephrine vs. exclusive isoprenaline stimulation in mice: critical contribution of alpha1-adrenoceptors to early cardiac stress responses. Dewenter, M., Pan, J., Knodler, L., Tzschockel, N., Henrich, J., Cordero, J., Dobreva, G., Lutz, S., Backs, J., Wieland, T. & Vettel, C. Basic Res Cardiol 117, 15 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35286475  

Transcatheter Tricuspid Valve Replacement With the EVOQUE System: 1-Year Outcomes of a Multicenter, First-in-Human Experience. Webb, J. G., Chuang, A. M., Meier, D., von Bardeleben, R. S., Kodali, S. K., Smith, R. L., Hausleiter, J., Ong, G., Boone, R., Ruf, T., George, I., Szerlip, M., Nabauer, M., Ali, F. M., Moss, R., Kreidel, F., Bapat, V., Schnitzler, K., Ye, J., Wild, M. et al. JACC Cardiovasc Interv 15, 481-491 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35272772  

Effect of Leisure Sports on Exercise Capacity and Quality of Life in Patients with a Fontan Circulation. Niemann, A., Rinne, K., Hansen, J. H., Scheewe, J., Uebing, A. & Voges, I. Am J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35279276  

Health Status Improvement with Ferric Carboxymaltose in Heart Failure with Reduced Ejection Fraction and Iron Deficiency. Butler, J., Khan, M. S., Friede, T., Jankowska, E. A., Fabien, V., Goehring, U. M., Dorigotti, F., Metra, M., Pina, I. L., Coats, A. J., Rosano, G., Comin-Colet, J., Van Veldhuisen, D. J., Filippatos, G. S., Anker, S. D. & Ponikowski, P. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35279929  

Use of evidence-based therapy in heart failure with reduced ejection fraction across age strata. Stolfo, D., Lund, L. H., Becher, P. M., Orsini, N., Thorvaldsen, T., Benson, L., Hage, C., Dahlstrom, U., Sinagra, G. & Savarese, G. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35278267  

Surrogate markers of gut dysfunction are related to heart failure severity and outcome - from the BIOSTAT-CHF consortium. Israr, M. Z., Zhan, H., Salzano, A., Voors, A. A., Cleland, J. G., Anker, S. D., Metra, M., van Veldhuisen, D. J., Lang, C. C., Zannad, F., Samani, N. J., Ng, L. L., Suzuki, T. & investigators, B.-C. Am Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35278373  

Endoaortic Balloon Occlusion During Minimally Invasive Mitral Valve Surgery. Van Praet, K. M., Kofler, M., Sundermann, S. H. & Kempfert, J. Innovations (Phila), 15569845221083047 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35275021  

To quantify or not to quantify, that is the question: Semi-quantitative vs. visual analysis of Rb-82 myocardial perfusion imaging PET. Rischpler, C., Kersting, D. & Nekolla, S. G. J Nucl Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35274212  

H-ABC- and dystonia-causing TUBB4A mutations show distinct pathogenic effects. Krajka, V., Vulinovic, F., Genova, M., Tanzer, K., Jijumon, A. S., Bodakuntla, S., Tennstedt, S., Mueller-Fielitz, H., Meier, B., Janke, C., Klein, C. & Rakovic, A. Sci Adv 8, eabj9229 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35275727  

Retraction notice to "Astragalus polysaccharide ameliorates lipopolysaccharide-induced cell injury in ATDC5 cells via miR-92a/KLF4 mediation" [Biomed. Pharmacother. 118 (2019) 109180]. Fan, L., Li, M., Cao, F. Y., Zeng, Z. W., Li, X. B., Ma, C., Ru, J. T. & Wu, X. J. Biomed Pharmacother 148, 112780 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35272895  

Regulation of Ion Channel Function in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Cancer Cell Secretion Through DNA Methylation. Zhong, R., Zhang, F., Yang, Z., Li, Y., Xu, Q., Lan, H., Lang, S., Cyganek, L., Burgermeister, E., El-Battrawy, I., Zhou, X., Akin, I. & Borggrefe, M. Front Cardiovasc Med 9, 839104 (2022).

Tph2 Gene Expression Defines Ethanol Drinking Behavior in Mice. Zaniewska, M., Mosienko, V., Bader, M. & Alenina, N. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35269497  

Chrono-pharmacology-based antiplatelet therapy for acute myocardial infarction. Tual-Chalot, S. & Stellos, K. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35266001  

Mitral valve prolapse: will genetics finally solve the puzzle? Trenkwalder, T. & Krane, M. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35265976  

Impact of energy drink versus coffee consumption on periodic repolarization dynamics: an interventional study. Schuttler, D., Rudi, W. S., Bauer, A., Hamm, W. & Brunner, S. Eur J Nutr (2022). https://www.ncbi.nlm.nih.gov/pubmed/35266046  

Angiotensin Converting Enzyme Inhibitors versus Receptor Blockers in Patients with Ventricular Tachyarrhythmias. Schupp, T., Behnes, M., Abumayyaleh, M., Weidner, K., Mashayekhi, K., Bertsch, T. & Akin, I. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35268553  

Cardiac Myxomas Resembling Malignant Neoplasia: Incidentally Diagnosed vs. Cerebral Embolized Myxomas. Salem, M., Hillmer, J., Friedrich, C., Panholzer, B., Saad, M., Salem, M., Frank, D., Ernst, M., Maetzler, W., Puehler, T., Lutter, G., Schoeneich, F., Haneya, A., Cremer, J. & Schoettler, J. Cancers (Basel) 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35267419  

Imaging of arrhythmia: Real-time cardiac magnetic resonance imaging in atrial fibrillation. Laubrock, K., von Loesch, T., Steinmetz, M., Lotz, J., Frahm, J., Uecker, M. & Unterberg-Buchwald, C. Eur J Radiol Open 9, 100404 (2022).

Local dose rate effects in implantable cardioverter-defibrillators with flattening filter free and flattened photon radiation. Gauter-Fleckenstein, B., Tulumen, E., Rudic, B., Borggrefe, M., Polednik, M. & Fleckenstein, J. Strahlenther Onkol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35267050  

Extracorporeal Membrane Oxygenation in Infarct-Related Cardiogenic Shock. Freund, A., Desch, S., Poss, J., Sulimov, D., Sandri, M., Majunke, N. & Thiele, H. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35268347  

A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. El-Sammak, H., Yang, B., Guenther, S., Chen, W., Marin-Juez, R. & Stainier, D. Y. R. Circ Res, CIRCRESAHA121319929 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35264012  

Single-cell technologies to decipher cardiovascular diseases. Abplanalp, W. T., Tucker, N. & Dimmeler, S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35265972  

Impact of baseline left ventricular ejection fraction on long-term outcomes in cardiac contractility modulation therapy. Yucel, G., Fastner, C., Hetjens, S., Toepel, M., Schmiel, G., Yazdani, B., Husain-Syed, F., Liebe, V., Rudic, B., Akin, I., Borggrefe, M. & Kuschyk, J. Pacing Clin Electrophysiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35262210  

The effects of common genetic variation in 96 genes involved in thyroid hormone regulation on TSH and FT4 concentrations. Sterenborg, R., Galesloot, T. E., Teumer, A., Netea-Maier, R. T., Speed, D., Meima, M. E., Visser, W. E., Smit, J. W. A., Peeters, R. P. & Medici, M. J Clin Endocrinol Metab (2022). https://www.ncbi.nlm.nih.gov/pubmed/35262175  

A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease. Shomroni, O., Sitte, M., Schmidt, J., Parbin, S., Ludewig, F., Yigit, G., Zelarayan, L. C., Streckfuss-Bomeke, K., Wollnik, B. & Salinas, G. Sci Rep 12, 4091 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35260714  

Pharmacological treatment options for heart failure with reduced ejection fraction: A 2022 update. Hellenkamp, K., Nolte, K. & von Haehling, S. Expert Opin Pharmacother, 1-8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35260016  

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients. Haupt, L. P., Rebs, S., Maurer, W., Hubscher, D., Tiburcy, M., Pabel, S., Maus, A., Kohne, S., Tappu, R., Haas, J., Li, Y., Sasse, A., Santos, C. C. X., Dressel, R., Wojnowski, L., Bunt, G., Mobius, W., Shah, A. M., Meder, B., Wollnik, B. et al. Basic Res Cardiol 117, 13 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35260914  

Evolution of Artificial Intelligence-Powered Technologies in Biomedical Research and Healthcare. Diaz-Flores, E., Meyer, T. & Giorkallos, A. Adv Biochem Eng Biotechnol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35262750  

Clinical frailty, and not features of acute infection, is associated with late mortality in COVID-19: a retrospective cohort study. Vlachogiannis, N. I., Baker, K. F., Georgiopoulos, G., Lazaridis, C., van der Loeff, I. S., Hanrath, A. T., Sopova, K., Tual-Chalot, S., Gatsiou, A., Spyridopoulos, I., Stamatelopoulos, K., Duncan, C. J. A. & Stellos, K. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35257497   

Missense Variant E1295K of Sodium Channel SCN5A Associated With Recurrent Ventricular Fibrillation and Myocardial Inflammation. Poller, W., Escher, F., Haas, J., Heidecker, B., Schultheiss, H. P., Attanasio, P., Skurk, C., Haghikia, A., Meder, B. & Klaassen, S. JACC Case Rep 4, 280-286 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35257103  

Carotid Intima-Media Thickness Percentiles in Adolescence and Young Adulthood and Their Association With Obesity and Hypertensive Blood Pressure in a Population Cohort. Neuhauser, H. K., Buschges, J., Schaffrath Rosario, A., Schienkiewitz, A., Sarganas, G., Konigstein, K., Schweizer, D. & Schmidt-Trucksass, A. Hypertension, HYPERTENSIONAHA12118521 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35255707  

Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing. Kogan, P. S., Wirth, F., Tomar, A., Darr, J., Teperino, R., Lahm, H., Dressen, M., Puluca, N., Zhang, Z., Neb, I., Beck, N., Luzius, T., de la Osa de la Rosa, L., Gartner, K., Huls, C., Zeidler, R., Ramanujam, D., Engelhardt, S., Wenk, C., Holdt, L. M. et al. Basic Res Cardiol 117, 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35258704  

How many molecules of mitochondrial complex I are in a cell? Ansari, F., Yoval, B., Niatsetskaya, Z., Ten, V., Wittig, I. & Galkin, A. Anal Biochem, 114646 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35259403  

Targeting the CCL2-CCR2 axis for atheroprotection. Georgakis, M. K., Bernhagen, J., Heitman, L. H., Weber, C. & Dichgans, M. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35253053  

Generation of heterozygous (MRli003-A-3) and homozygous (MRli003-A-4) TRPM4 knockout human iPSC lines. Zhang, F., Meier, A. B., Lipp, P., Laugwitz, K. L., Dorn, T. & Moretti, A. Stem Cell Res 60, 102731 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35245852  

Isotropic 3D compressed sensing (CS) based sequence is comparable to 2D-LGE in left ventricular scar quantification in different disease entities. Fenski, M., Grandy, T. H., Viezzer, D., Kertusha, S., Schmidt, M., Forman, C. & Schulz-Menger, J. Int J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35243574  

[Morphological and functional diagnostics of coronary artery disease by computed tomography]. Baumann, S., Overhoff, D., Tesche, C., Korosoglou, G., Kelle, S., Nassar, M., Buss, S. J., Andre, F., Renker, M., Schoepf, U. J., Akin, I., Waldeck, S., Schoenberg, S. O. & Lossnitzer, D. Herz (2022). https://www.ncbi.nlm.nih.gov/pubmed/35244729  

Durability of benefit after transcatheter tricuspid valve intervention: insights from actigraphy. Stocker, T. J., Cohen, D. J., Arnold, S. V., Sommer, S., Braun, D., Stolz, L., Hertell, H., Weckbach, L. T., Wild, M. G., Doldi, P., Orban, M., Orban, M., Deseive, S., Higuchi, S., Massberg, S., Nabauer, M. & Hausleiter, J. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35239253  

CT or Invasive Coronary Angiography in Stable Chest Pain. Group, D. T., Maurovich-Horvat, P., Bosserdt, M., Kofoed, K. F., Rieckmann, N., Benedek, T., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Stechovsky, C., Sakalyte, G., Cemerlic Adic, N., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M. et al. N Engl J Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35240010  

Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques. Egea, V., Megens, R. T. A., Santovito, D., Wantha, S., Brandl, R., Siess, W., Khani, S., Soehnlein, O., Bartelt, A., Weber, C. & Ries, C. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35238350  

Visceral and renal malperfusion syndromes in acute aortic dissection type A: the fate of the branch vessel. Buech, J., Radner, C., Fabry, T. G., Horke, K. M., Ali, A., Saha, S., Hagl, C., Pichlmaier, M. A. & Peterss, S. J Cardiovasc Surg (Torino) (2022). https://www.ncbi.nlm.nih.gov/pubmed/35238524  

Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study. Portilla-Fernandez, E., Klarin, D., Hwang, S. J., Biggs, M. L., Bis, J. C., Weiss, S., Rospleszcz, S., Natarajan, P., Hoffmann, U., Rogers, I. S., Truong, Q. A., Volker, U., Dorr, M., Bulow, R., Criqui, M. H., Allison, M., Ganesh, S. K., Yao, J., Waldenberger, M., Bamberg, F. et al. Hum Mol Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35234888  

Links between ectopic and abdominal fat and systemic inflammation: New insights from the SHIP-Trend study. Ponce-de-Leon, M., Hannemann, A., Linseisen, J., Nauck, M., Lerch, M. M., Bulow, R., Volzke, H., Friedrich, N., Kassubek, J., Muller, H. P., Baumeister, S. E. & Meisinger, C. Dig Liver Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35232676  

From atherosclerosis to myocardial infarction - a process-oriented model investigating the role of risk factors. Simonetto, C., Heier, M., Peters, A., Kaiser, J. C. & Rospleszcz, S. Am J Epidemiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35231928  

DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. Seredinski, S., Boos, F., Gunther, S., Oo, J. A., Warwick, T., Izquierdo Ponce, J., Lillich, F. F., Proschak, E., Knapp, S., Gilsbach, R., Pfluger-Muller, B., Brandes, R. P. & Leisegang, M. S. Mol Ther Nucleic Acids 27, 1023-1035 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35228897  

Short-term effects of cold spells on plasma viscosity: Results from the KORA cohort study in Augsburg, Germany. Ni, W., Schneider, A., Wolf, K., Zhang, S., Chen, K., Koenig, W., Peters, A. & Breitner, S. Environ Pollut 302, 119071 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35231540  

RGS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes. Levay, M. K., Krobert, K. A., Vogt, A., Ahmad, A., Jungmann, A., Neuber, C., Pasch, S., Hansen, A., Muller, O. J., Lutz, S. & Wieland, T. Basic Res Cardiol 117, 8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35230541  

Thrombus formation at the inflow cannula of continuous-flow left ventricular assist devices-A systematic analysis. Kaufmann, F., Hormandinger, C., Knosalla, C., Falk, V. & Potapov, E. Artif Organs (2022). https://www.ncbi.nlm.nih.gov/pubmed/35230721  

Ticagrelor Monotherapy or Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation: Per-Protocol Analysis of the GLOBAL LEADERS Trial. Gragnano, F., Zwahlen, M., Vranckx, P., Heg, D., Schmidlin, K., Hamm, C., Steg, P. G., Gargiulo, G., McFadden, E. P., Onuma, Y., Chichareon, P., Benit, E., Mollmann, H., Janssens, L., Leonardi, S., Zurakowski, A., Arrivi, A., Van Geuns, R. J., Huber, K., Slagboom, T. et al. J Am Heart Assoc, e024291 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35229616  

Thyroid function, pernicious anemia, and erythropoiesis: a two-sample Mendelian randomization study. Kjaergaard, A. D., Teumer, A., Marouli, E., Deloukas, P., Kus, A., Sterenborg, R., Asvold, B. O., Medici, M. & Ellervik, C. Hum Mol Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35225327  


Februar

 

 

Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide-Based Hybrid Compounds against SARS-CoV-2 and Cancer. Herrmann, L., Yaremenko, I. A., Çapcı, A., Struwe, J., Tailor, D., Dheeraj, A., Hodek, J., Belyakova, Y. Y., Radulov, P. S., Weber, J., Malhotra, S. V., Terent'ev, A. O., Ackermann, L. & Tsogoeva, S. B. ChemMedChem 17, e202200005 (2022).

Hypothalamic Galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop. Corradi, L., Bruzzone, M., Maschio, M. D., Sawamiphak, S. & Filosa, A. Curr Biol 32, 1497-1510 e1495 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35219430  

Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial. Diab, M., Lehmann, T., Bothe, W., Akhyari, P., Platzer, S., Wendt, D., Deppe, A. C., Strauch, J., Hagel, S., Gunther, A., Faerber, G., Sponholz, C., Franz, M., Scherag, A., Velichkov, I., Silaschi, M., Fassl, J., Hofmann, B., Lehmann, S., Schramm, R. et al. Circulation 145, 959-968 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35213213  

Redox-dependent loss of flavin by mitochondria complex I is different in brain and heart. Yoval-Sanchez, B., Ansari, F., James, J., Niatsetskaya, Z., Sosunov, S., Filipenko, P., Tikhonova, I. G., Ten, V., Wittig, I., Rafikov, R. & Galkin, A. Redox Biol 51, 102258 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35189550

A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome. Widjaja, A. A., Shekeran, S. G., Adami, E., Ting, J. G. W., Tan, J., Viswanathan, S., Lim, S. Y., Tan, P. H., Hubner, N., Coffman, T. & Cook, S. A. J Am Soc Nephrol 33, 718-730 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35140116

Computed tomographic assessment of right ventricular long axis strain for prognosis after transcatheter aortic valve replacement. Aquino, G. J., Decker, J. A., Schoepf, U. J., Carson, L., Fiegel, M., Paladugu, N., Brandt, V., Yacoub, B., Emrich, A. L., Kroencke, T., Burt, J. R., Bayer, R., 2nd, Emrich, T. & Varga-Szemes, A. Eur J Radiol 149, 110212 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35220197  

Impact of the 2009 ESC Guideline Change on Surgically Treated Infective Endocarditis. Weber, C., Luehr, M., Petrov, G., Misfeld, M., Akhyari, P., Tugtekin, S. M., Diab, M., Saha, S., Elderia, A., Lichtenberg, A., Hagl, C., Doenst, T., Matschke, K., Borger, M. A., Wahlers, T. & Clinical, M. P. o. A. o. I. E. i. G. S. G. Ann Thorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35216990   

Interferon-beta Suppresses Transcriptionally Active Parvovirus B19 Infection in Viral Cardiomyopathy: A Subgroup Analysis of the BICC-Trial. Schultheiss, H. P., Bock, C. T., Aleshcheva, G., Baumeier, C., Poller, W. & Escher, F. Viruses 14 (2022). www.ncbi.nlm.nih.gov/pubmed/35216037

A potential future Fontan modification: preliminary in vitro data of a pressure-generating tube from engineered heart tissue. Kohne, M., Behrens, C. S., Studemann, T., Bibra, C. V., Querdel, E., Shibamiya, A., Geertz, B., Olfe, J., Huners, I., Jockenhovel, S., Hubler, M., Eschenhagen, T., Sachweh, J. S., Weinberger, F. & Biermann, D. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35218664   

Phenotypic spectrum of BLM- and RMI1-related Bloom syndrome. Gonenc, II, Elcioglu, N. H., Martinez Grijalva, C., Aras, S., Grossmann, N., Praulich, I., Altmuller, J., Kaulfuss, S., Li, Y., Nurnberg, P., Burfeind, P., Yigit, G. & Wollnik, B. Clin Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35218564   

Symptom Severity and Health-Related Quality of Life in Patients with Atrial Fibrillation: Findings from the Observational ARENA Study. Sadlonova, M., Senges, J., Nagel, J., Celano, C., Klasen-Max, C., Borggrefe, M., Akin, I., Thomas, D., Schwarzbach, C. J., Kleeman, T., Schneider, S., Hochadel, M., Suselbeck, T., Schwacke, H., Alonso, A., Haass, M., Ladwig, K. H. & Herrmann-Lingen, C. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35207412  

Improving adaptive seamless designs through Bayesian optimization. Richter, J., Friede, T. & Rahnenfuhrer, J. Biom J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35212423  

Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel. Puccini, M., Rauch, C., Jakobs, K., Friebel, J., Hassanein, A., Landmesser, U. & Rauch, U. Cardiovasc Drugs Ther (2022). https://www.ncbi.nlm.nih.gov/pubmed/35211819  

Of hypes and paradigms in the search of the ideal valved conduit in the young. Peterss, S., Hagl, C. & Pichlmaier, M. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35213693  

Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells. Muller, N., Warwick, T., Noack, K., Malacarne, P. F., Cooper, A. J. L., Weissmann, N., Schroder, K., Brandes, R. P. & Rezende, F. Antioxidants (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35204316  

Intracranial haemorrhage in adult patients on venoarterial extracorporeal membrane oxygenation. Lusebrink, E., Zimmer, S., Schrage, B., Dabboura, S., Majunke, N., Scherer, C., Aksoy, A., Krogmann, A., Hoffmann, S., Szczanowicz, L., Binzenhofer, L., Peterss, S., Kuhn, C., Hagl, C., Massberg, S., Schafer, A., Thiele, H., Westermann, D., Orban, M. & Group, I.-V.-E. I. Eur Heart J Acute Cardiovasc Care (2022). https://www.ncbi.nlm.nih.gov/pubmed/35213724  

Polygenic risk score: a tool ready for clinical use? Kavousi, M. & Schunkert, H. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35211747  

Polycystic ovarian syndrome increases prevalence of concentric hypertrophy in normotensive obese women. De Jong, K. A., Berisha, F., Naderpoor, N., Appelbe, A., Kotowicz, M. A., Cukier, K., McGee, S. L. & Nikolaev, V. O. PLoS One 17, e0263312 (2022).

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Barc, J., Tadros, R., Glinge, C., Chiang, D. Y., Jouni, M., Simonet, F., Jurgens, S. J., Baudic, M., Nicastro, M., Potet, F., Offerhaus, J. A., Walsh, R., Choi, S. H., Verkerk, A. O., Mizusawa, Y., Anys, S., Minois, D., Arnaud, M., Duchateau, J., Wijeyeratne, Y. D. et al. Nat Genet 54, 232-239 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35210625

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection. Pekayvaz, K., Leunig, A., Kaiser, R., Joppich, M., Brambs, S., Janjic, A., Popp, O., Nixdorf, D., Fumagalli, V., Schmidt, N., Polewka, V., Anjum, A., Knottenberg, V., Eivers, L., Wange, L. E., Gold, C., Kirchner, M., Muenchhoff, M., Hellmuth, J. C., Scherer, C. et al. Nat Commun 13, 1018 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35197461  

Influence of ejection fraction on biomarker expression and response to spironolactone in people at risk of heart failure: findings from the HOMAGE trial. Ferreira, J. P., Verdonschot, J. A. J., Girerd, N., Bozec, E., Pellicori, P., Collier, T., Mariottoni, B., Cosmi, F., Hazebroek, M., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelman, F., Clark, A. L., Diez, J., Gonzalez, A., Rossignol, P., Cleland, J. G. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35199421  

Percutaneous coronary intervention for chronic total occlusion in octogenarians: a propensity score study. Blessing, R. R. L., Ahoopai, M., Geyer, M., Brandt, M., Zeiher, A. M., Vasa-Nicotera, M., Munzel, T., Wenzel, P., Gori, T. & Dimitriadis, Z. Sci Rep 12, 3073 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35197506  

Renin, aldosterone, the aldosterone-to-renin ratio, and incident hypertension among normotensive subjects from the general population. Arnold, N., Hermanns, I. M., Schulz, A., Hahad, O., Schmitt, V. H., Panova-Noeva, M., Prochaska, J. H., Binder, H., Pfeiffer, N., Beutel, M., Lackner, K. J., Munzel, T. & Wild, P. S. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35199135  

Role of TRPC6 in kidney damage after acute ischemic kidney injury. Zheng, Z., Tsvetkov, D., Bartolomaeus, T. U. P., Erdogan, C., Krugel, U., Schleifenbaum, J., Schaefer, M., Nurnberg, B., Chai, X., Ludwig, F. A., N'Diaye, G., Kohler, M. B., Wu, K., Gollasch, M. & Marko, L. Sci Rep 12, 3038 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35194063  

Effects of Atrial Fibrillation on the Human Ventricle. Pabel, S., Knierim, M., Stehle, T., Alebrand, F., Paulus, M., Sieme, M., Herwig, M., Barsch, F., Kortl, T., Poppl, A., Wenner, B., Ljubojevic-Holzer, S., Molina, C. E., Dybkova, N., Camboni, D., Fischer, T. H., Sedej, S., Scherr, D., Schmid, C., Brochhausen, C. et al. Circ Res, CIRCRESAHA121319718 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35193397  

Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging: From Basic Concepts to Emerging Methods. Holtackers, R. J., Emrich, T., Botnar, R. M., Kooi, M. E., Wildberger, J. E. & Kreitner, K. F. Rofo (2022). https://www.ncbi.nlm.nih.gov/pubmed/35196714  

Surgery for infective endocarditis following low-intermediate risk transcatheter aortic valve replacement-a multicentre experience. Saha, S., Joskowiak, D., Marin-Cuartas, M., Diab, M., Schwaiger, B. M., Sandoval-Boburg, R., Popov, A. F., Weber, C., Varghese, S., Martens, A., Cebotari, S., Scherner, M., Eichinger, W., Holzhey, D., Dohle, D. S., Wahlers, T., Doenst, T., Misfeld, M., Mehilli, J., Massberg, S. et al. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35190828   

Effect of Sunitinib Treatment on Skin Sodium Accumulation in Patients With Renal Cancer: a Pilot Study. Marko, L., Dorr, A., Linz, P., van den Meiracker, A. H., Garrelds, I. M., Kuehne, T., Dechend, R., Danser, A. H. J., Florcken, A. & Muller, D. N. Hypertension, HYPERTENSIONAHA12219079 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35189705  

Preadmission antiplatelet therapy and treatment effect of ticagrelor versus prasugrel in patients with acute coronary syndromes - a subgroup analysis of the ISAR-REACT 5 trial. Lahu, S., Ndrepepa, G., Neumann, F. J., Menichelli, M., Bernlochner, I., Richardt, G., Wohrle, J., Witzenbichler, B., Hemetsberger, R., Mayer, K., Akin, I., Cassese, S., Gewalt, S., Xhepa, E., Kufner, S., Valina, C., Sager, H. B., Joner, M., Ibrahim, T., Laugwitz, K. L. et al. Eur Heart J Cardiovasc Pharmacother (2022). https://www.ncbi.nlm.nih.gov/pubmed/35191982  

Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study. Kaura, A., Hartley, A., Panoulas, V., Glampson, B., Shah, A. S. V., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Thursz, M. R., Elliott, P., Hemmingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Trickey, A., Sterne, J. A., Haskard, D. O. et al. PLoS Med 19, e1003911 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35192610  

Predictors of cardiopulmonary fitness in cancer-affected and -unaffected women with a pathogenic germline variant in the genes BRCA1/2 (LIBRE-1). Berling-Ernst, A., Yahiaoui-Doktor, M., Kiechle, M., Engel, C., Lammert, J., Grill, S., Dukatz, R., Rhiem, K., Baumann, F. T., Bischoff, S. C., Erickson, N., Schmidt, T., Niederberger, U., Siniatchkin, M. & Halle, M. Sci Rep 12, 2907 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35190584  

QRS micro-fragmentation as a mortality predictor. Hnatkova, K., Andrsova, I., Novotny, T., Britton, A., Shipley, M., Vandenberk, B., Sprenkeler, D. J., Junttila, J., Reichlin, T., Schlogl, S., Vos, M. A., Friede, T., Bauer, A., Huikuri, H. V., Willems, R., Schmidt, G., Franz, M. R., Sticherling, C., Zabel, M. & Malik, M. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35187560  

 

 

MRI-Detected Brain Lesions and Cognitive Function in Patients With Atrial Fibrillation Undergoing Left Atrial Catheter Ablation in the Randomized AXAFA-AFNET 5 Trial. Haeusler, K. G., Eichner, F. A., Heuschmann, P. U., Fiebach, J. B., Engelhorn, T., Blank, B., Callans, D., Elvan, A., Grimaldi, M., Hansen, J., Hindricks, G., Al-Khalidi, H. R., Mont, L., Nielsen, J. C., Piccini, J. P., Schotten, U., Themistoclakis, S., Vijgen, J., Di Biase, L. & Kirchhof, P. Circulation 145, 906-915 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35135308  

Neurofilament proteins as a potential biomarker in chemotherapy-induced polyneuropathy. Huehnchen, P., Schinke, C., Bangemann, N., Dordevic, A. D., Kern, J., Maierhof, S. K., Hew, L., Nolte, L., Kortvelyessy, P., Gopfert, J. C., Ruprecht, K., Somps, C. J., Blohmer, J. U., Sehouli, J., Endres, M. & Boehmerle, W. JCI Insight 7 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35133982  

Severe heart failure in the setting of inflammatory cardiomyopathy with likely pathogenic titin variant. Mueller, M., Zwinger, L., Klaassen, S., Poller, W., Monserrat Iglesias, L., Pablo Ochoa, J., Klingel, K., Landmesser, U. & Heidecker, B. Int J Cardiol Heart Vasc 39, 100969 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35198726  

 

Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy. Huang, M., Yang, Z., Li, Y., Lan, H., Cyganek, L., Yuecel, G., Lang, S., Bieback, K., El-Battrawy, I., Zhou, X., Borggrefe, M. & Akin, I. Frontiers in Cardiovascular Medicine 8, 777463 (2022).

Bacteriophage therapy as a treatment option for complex cardiovascular implant infection: The German Heart Center Berlin experience. Tkhilaishvili, T., Potapov, E., Starck, C., Mulzer, J., Falk, V., Trampuz, A. & Schoenrath, F. The Journal of Heart and Lung Transplantation (2022).

Interventional Procedures for Left Ventricular Assist Device-Associated Complications. Lanmueller, P., Eulert-Grehn, J.-J., Unbehaun, A., Klein, C., Hommel, M., Kofler, M., Kempfert, J., Hoermandinger, C., Kaufmann, F., Stawowy, P., Dreysse, S., Mulzer, J., Mueller, M., Falk, V., Schoenrath, F., Potapov, E. & Just, I. A. ASAIO Journal Publish Ahead of Print (2022).

Coronary angiography in acute ischemic stroke patients: frequency and determinants of pathological findings in a multicenter cohort study. Litmeier, S., Meinel, T. R., von Rennenberg, R., Kniepert, J. U., Audebert, H. J., Endres, M., Jung, S., Scheitz, J. F. & Nolte, C. H. J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35182178   

Conduction disturbances following transcatheter aortic valve implantation: Any room for improvement? Charitos, E. & Kim, W. K. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35182652  

Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease. Talmor-Barkan, Y., Bar, N., Shaul, A. A., Shahaf, N., Godneva, A., Bussi, Y., Lotan-Pompan, M., Weinberger, A., Shechter, A., Chezar-Azerrad, C., Arow, Z., Hammer, Y., Chechi, K., Forslund, S. K., Fromentin, S., Dumas, M. E., Ehrlich, S. D., Pedersen, O., Kornowski, R. & Segal, E. Nat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35177859  

Nationwide Registry-Based Analysis of Infective Endocarditis Risk After Pulmonary Valve Replacement. Stammnitz, C., Huscher, D., Bauer, U. M. M., Urban, A., Nordmeyer, J., Schubert, S., Photiadis, J., Berger, F., Klaassen, S. & German Competence Network for Congenital Heart Defects, I. J Am Heart Assoc, e022231 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35179045  

Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis. Pappritz, K., Lin, J., El-Shafeey, M., Fechner, H., Kuhl, U., Alogna, A., Spillmann, F., Elsanhoury, A., Schulz, R., Tschope, C. & Van Linthout, S. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35178861  

Microbiome and metabolome features of the cardiometabolic disease spectrum. Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. et al. Nat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35177860  

Not only lungs: COVID-19 hits platelets as well. Bongiovanni, D., Klug, M., Valgimigli, M. & Bernlochner, I. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35178570  

The Association of Depression and All-Cause Mortality: Explanatory Factors and the Influence of Gender. Wicke, F. S., Ernst, M., Otten, D., Werner, A., Dreier, M., Brahler, E., Tibubos, A. N., Reiner, I., Michal, M., Wiltink, J., Munzel, T., Lackner, K. J., Pfeiffer, N., Konig, J., Wild, P. S. & Beutel, M. E. J Affect Disord (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176339  

Rodent models for gait network disorders in Parkinson's disease - a translational perspective. Wenger, N., Vogt, A., Skrobot, M., Garulli, E. L., Kabaoglu, B., Salchow-Hommen, C., Schauer, T., Kroneberg, D., Schuhmann, M., Ip, C. W., Harms, C., Endres, M., Isaias, I., Tovote, P. & Blum, R. Exp Neurol, 114011 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176273   

Evaluation of the spline reconstruction technique for preclinical PET imaging. Vrachliotis, A., Kastis, G. A., Protonotarios, N. E., Fokas, A. S., Nekolla, S. G., Anagnostopoulos, C. D., Costaridou, L. & Gaitanis, A. Comput Methods Programs Biomed 217, 106668 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176596  

CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes. Stathopoulou, K., Schnittger, J., Raabe, J., Fleischer, F., Mangels, N., Piasecki, A., Findlay, J., Hartmann, K., Krasemann, S., Schlossarek, S., Uebeler, J., Wixler, V., Blake, D. J., Baillie, G. S., Carrier, L., Ehler, E. & Cuello, F. FEBS J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176204  

Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes. Li, L., Chen, Z., von Scheidt, M., Li, S., Steiner, A., Guldener, U., Koplev, S., Ma, A., Hao, K., Pan, C., Lusis, A. J., Pang, S., Kessler, T., Ermel, R., Sukhavasi, K., Ruusalepp, A., Gagneur, J., Erdmann, J., Kovacic, J. C., Bjorkegren, J. L. M. et al. Basic Res Cardiol 117, 6 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35175464  

Deep breathing couples CSF and venous flow dynamics. Kollmeier, J. M., Gurbuz-Reiss, L., Sahoo, P., Badura, S., Ellebracht, B., Keck, M., Gartner, J., Ludwig, H. C., Frahm, J. & Dreha-Kulaczewski, S. Sci Rep 12, 2568 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35173200  

Neutrophil-Platelet Interactions as Novel Treatment Targets in Cardiovascular Disease. Kaiser, R., Escaig, R., Erber, J. & Nicolai, L. Front Cardiovasc Med 8, 824112 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35174225  

Prognostic Implications of a Second Peak of High-Sensitivity Troponin T After Myocardial Infarction. Hartikainen, T. S., Gossling, A., Sorensen, N. A., Lehmacher, J., Neumann, J. T., Blankenberg, S. & Westermann, D. Front Cardiovasc Med 8, 780198 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35174220  

A novel Troponin I mutation associated with severe restrictive cardiomyopathy-a case report of a 27-year-old woman with fatigue. Gerhardt, T., Monserrat, L., Landmesser, U. & Poller, W. Eur Heart J Case Rep 6, ytac053 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35174310  

Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development. Frenis, K., Kalinovic, S., Ernst, B. P., Kvandova, M., Al Zuabi, A., Kuntic, M., Oelze, M., Stamm, P., Bayo Jimenez, M. T., Kij, A., Keppeler, K., Klein, V., Strohm, L., Ubbens, H., Daub, S., Hahad, O., Kroller-Schon, S., Schmeisser, M. J., Chlopicki, S., Eckrich, J. et al. Front Mol Biosci 8, 814921 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35174211  

Treatment standards for direct oral anticoagulants in patients with acute ischemic stroke and non-valvular atrial fibrillation: A survey among German stroke units. Fastner, C., Szabo, K., Samartzi, M., Kruska, M., Akin, I., Platten, M., Baumann, S. & Alonso, A. PLoS One 17, e0264122 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176109  

Muscarinic receptor activation reduces force and arrhythmias in human atria independent of IK,ACh. Petersen, J., Castro, L., Pedersen Bengaard, A. K., Pecha, S., Ismaili, D., Schulz, C., Sahni, J., Steenpass, A., Meier, C., Reichenspurner, H., Jespersen, T., Eschenhagen, T. & Christ, T. J Cardiovasc Pharmacol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170489  

Distribution and prognostic impact of coronary artery disease and nonischemic cardiomyopathies in patients with electrical storm. Muller, J., Behnes, M., Ellguth, D., Schupp, T., Taton, G., Reiser, L., Engelke, N., Borggrefe, M., Reichelt, T., Bollow, A., Kim, S. H., Barth, C., Weidner, K., Battrawy, I. E., Ansari, U., Akin, M., Grosse Meininghaus, D., Mashayekhi, K. & Akin, I. Coron Artery Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170551  

Patient profile and outcomes associated with follow-up in specialty vs. primary care in heart failure. Lindberg, F., Lund, L. H., Benson, L., Schrage, B., Edner, M., Dahlstrom, U., Linde, C., Rosano, G. & Savarese, G. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170237  

Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I. Kamynina, A., Guttzeit, S., Eaton, P. & Cuello, F. Hypertension, HYPERTENSIONAHA12218756 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35168371  

One-year results following PASCAL-based or MitraClip-based mitral valve transcatheter edge-to-edge repair. Geis, N. A., Schlegel, P., Heckmann, M. B., Katus, H. A., Frey, N., Crespo Lopez, P. & Raake, P. W. J. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170230  

The role of epigenetic clocks in explaining educational inequalities in mortality: a multi-cohort study and meta-analysis. Fiorito, G., Pedron, S., Ochoa-Rosales, C., McCrory, C., Polidoro, S., Zhang, Y., Dugue, P. A., Ratliff, S., Zhao, W. N., McKay, G. J., Costa, G., Solinas, M. G., Mullan Harris, K., Tumino, R., Grioni, S., Ricceri, F., Panico, S., Brenner, H., Schwettmann, L., Waldenberger, M. et al. J Gerontol A Biol Sci Med Sci (2022). https://www.ncbi.nlm.nih.gov/pubmed/35172329  

Reply to Van den Eyde et al. Voges, I. & Gabbert, D. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35167668  

Tackling postoperative sudden cardiac death in high-risk cardiac surgical patients-role of wearable cardioverter defibrillators. Starck, C., Kaemmel, J. & Falk, V. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35165712  

Iron Deficiency and Reduced Muscle Strength in Patients with Acute and Chronic Ischemic Stroke. Scherbakov, N., Sandek, A., Valentova, M., Mayer, A., von Haehling, S., Jankowska, E., Anker, S. D. & Doehner, W. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35160047  

Population-based screening in children for early diagnosis and treatment of familial hypercholesterolemia: design of the VRONI study. Sanin, V., Schmieder, R., Ates, S., Schlieben, L. D., Wiehler, J., Sun, R., Decker, M., Sander, M., Holdenrieder, S., Kohlmayer, F., Friedmann, A., Mall, V., Feiler, T., Dressler, A., Strom, T. M., Prokisch, H., Meitinger, T., von Scheidt, M., Koenig, W., Leipold, G. et al. Eur J Public Health (2022). https://www.ncbi.nlm.nih.gov/pubmed/35165720   

Association between Duration of Deep Hypothermic Circulatory Arrest and Surgical Outcome in Patients with Acute Type A Aortic Dissection: A Large Retrospective Cohort Study. Salehi Ravesh, M., Friedrich, C., Schoettler, J., Hummitzsch, L., Elke, G., Salem, M., Lutter, G., Puehler, T., Cremer, J. & Haneya, A. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35160094  

Longitudinal association of Apolipoprotein E polymorphism with lipid profile, type 2 diabetes and metabolic syndrome: Results from a 15 year follow-up study. Pitchika, A., Ricardo Paulista Markus, M., Schipf, S., Teumer, A., Van der Auwera, S., Nauck, M., Dorr, M., Felix, S., Jorgen Grabe, H., Volzke, H. & Ittermann, T. Diabetes Res Clin Pract 185, 109778 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35167921  

Switching in the expression pattern of actin isoforms marks the onset of contractility and distinct mechanodynamic behavior during cardiomyocyte differentiation. Pires, R. H., Dau, T. H., Manu, E., Shree, N. & Otto, O. Physiol Rep 10, e15171 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35166060  

Soluble ST2 Receptor: Biomarker of Left Ventricular Impairment and Functional Status in Patients with Inflammatory Cardiomyopathy. Obradovic, D. M., Buttner, P., Rommel, K. P., Blazek, S., Loncar, G., von Haehling, S., von Roeder, M., Lucke, C., Gutberlet, M., Thiele, H., Lurz, P. & Besler, C. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35159224  

The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure. Kubin, T., Gajawada, P., Bramlage, P., Hein, S., Berge, B., Cetinkaya, A., Burger, H., Schonburg, M., Schaper, W., Choi, Y. H. & Richter, M. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35163735  

Improving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data. Gheorghita, B. A., Itu, L. M., Sharma, P., Suciu, C., Wetzl, J., Geppert, C., Ali, M. A. A., Lee, A. M., Piechnik, S. K., Neubauer, S., Petersen, S. E., Schulz-Menger, J. & Chitiboi, T. Sci Rep 12, 2391 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35165324  

Iron deficiency is related to low functional outcome in patients at early rehabilitation after acute stroke. Doehner, W., Scherbakov, N., Schellenberg, T., Jankowska, E. A., Scheitz, J. F., von Haehling, S. & Joebges, M. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35166066  

Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants. Speck, D., Kleinau, G., Meininghaus, M., Erbe, A., Einfeldt, A., Szczepek, M., Scheerer, P. & Putter, V. Front Pharmacol 12, 826112 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35153771  

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19. Sala, L., Leonov, V., Mura, M., Giannetti, F., Khudiakov, A., Moretti, A., Crotti, L., Gnecchi, M. & Schwartz, P. J. Front Physiol 12, 730127 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35153806  

Paracrine Interleukin 6 Induces Cerebral Remodeling at Early Stages After Unilateral Common Carotid Artery Occlusion in Mice. Kuffner, M. T. C., Koch, S. P., Kirchner, M., Mueller, S., Lips, J., An, J., Mertins, P., Dirnagl, U., Endres, M., Boehm-Sturm, P., Harms, C. & Hoffmann, C. J. Front Cardiovasc Med 8, 805095 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35155612  

Stroke events after transcatheter aortic valve implantation: Temporal relationships and affected brain regions. Linder, M., Higgen, F. L., Voigtlander, L., Weimann, J., Ludwig, S., Waldschmidt, L., Focke, C., Bhadra, O., Grundmann, D., Demal, T., von Zastrow, A., Schafer, A., Schirmer, J., Reichenspurner, H., Blankenberg, S., Westermann, D., Schofer, N., Conradi, L., Thomalla, G. & Seiffert, M. Am Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35149038  

The European Registry for Patients with Mechanical Circulatory Support of the European Association for Cardio-Thoracic Surgery: third report. de By, T., Schoenrath, F., Veen, K. M., Mohacsi, P., Stein, J., Alkhamees, K. M. M., Anastasiadis, K., Berhnardt, A., Beyersdorf, F., Caliskan, K., Reineke, D., Damman, K., Fiane, A., Gkouziouta, A., Gollmann-Tepekoylu, C., Finn, G., Hulman, M., Iacovoni, A., Loforte, A., Merkely, B. et al. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35150247  

Impact of prenatal and childhood adversity effects around World War II on multimorbidity: results from the KORA-Age study. Arshadipour, A., Thorand, B., Linkohr, B., Rospleszcz, S., Ladwig, K. H., Heier, M. & Peters, A. BMC Geriatr 22, 115 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35148691  

Target and non-target vessel related events at 10 years post percutaneous coronary intervention. Coughlan, J. J., Aytekin, A., Xhepa, E., Cassese, S., Joner, M., Koch, T., Wiebe, J., Lenz, T., Rheude, T., Pellegrini, C., Gewalt, S., Ibrahim, T., Laugwitz, K. L., Schunkert, H., Kastrati, A. & Kufner, S. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35147767  

Ticagrelor after Acute Coronary Syndrome: One For All or Part of Personalized Medicine? Akin, I. & Nienaber, C. A. Lancet Reg Health Eur 14, 100309 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35146475  

Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies. Rodriguez-Polo, I. & Behr, R. Neural Regen Res 17, 1867-1874 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35142660  

Serum Calcification Propensity and Calcification of the Abdominal Aorta in Patients With Primary Aldosteronism. Kantauskaite, M., Bolten, K., Boschheidgen, M., Schmidt, C., Kolb, T., Eckardt, K. U., Pasch, A., Schimmoller, L., Rump, L. C., Voelkl, J. & Stegbauer, J. Front Cardiovasc Med 9, 771096 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35141300  

Functional improvement following direct interventional leaflet repair of severe tricuspid regurgitation. Volz, M. J., Hoerbrand, I., Konstandin, M. H., Mereles, D., Weiss, C., Warnecke, G., Frey, N., Aurich, M. & Raake, P. W. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137567  

The additional use of strain measurements for timing of treatment in severe aortic regurgitation. Sinning, C. Int J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35138473  

Feasibility and preliminary efficacy of perioperative interventions in patients undergoing coronary artery bypass grafting: the randomized controlled I-COPE trial. Sadlonova, M., Nagel, J., Becker, S., Neumann, S., Staab, J., Meyer, T., Celano, C. M., Amonoo, H. L., Fangauf, S. V., Herrmann-Lingen, C., Kutschka, I. & Friedrich, M. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137022  

Thyroid Function and the Risk of Prediabetes and Type 2 Diabetes. Roa Duenas, O. H., Van der Burgh, A. C., Ittermann, T., Ligthart, S., Ikram, M. A., Peeters, R. & Chaker, L. J Clin Endocrinol Metab (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137143  

Atrial fibrillation in patients on left ventricular assist device support-to treat or not to treat. Potapov, E. V. & Schoenrath, F. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137027  

Targeted proteomics improves cardiovascular risk prediction in secondary prevention. Nurmohamed, N. S., Belo Pereira, J. P., Hoogeveen, R. M., Kroon, J., Kraaijenhof, J. M., Waissi, F., Timmerman, N., Bom, M. J., Hoefer, I. E., Knaapen, P., Catapano, A. L., Koenig, W., de Kleijn, D., Visseren, F. L. J., Levin, E., Stroes, E. S. G. & Group, U.-S. S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35139537  

Prognostic impact of secondary prevention after coronary artery bypass grafting-insights from the TiCAB trial. Heer, T., von Scheidt, M., Boening, A., Heyken, C., Gusmini, F., de Waha, A., Kuna, C., Fach, A., Grothusen, C., Oberhoffer, M., Knosalla, C., Walther, T., Danner, B. C., Misfeld, M., Wimmer-Greinecker, G., Siepe, M., Grubitzsch, H., Joost, A., Schaefer, A., Conradi, L. et al. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35138350  

MRI-Detected Brain Lesions and Cognitive Function in Atrial Fibrillation Patients Undergoing Left Atrial Catheter Ablation in the Randomized AXAFA-AFNET 5 Trial. Hausler, K. G., Eichner, F. A., Heuschmann, P. U., Fiebach, J. B., Engelhorn, T., Blank, B., Callans, D., Elvan, A., Grimaldi, M., Hansen, J., Hindricks, G., Al-Khalidi, H. R., Mont, L., Nielsen, J. C., Piccini, J. P., Schotten, U., Themistoclakis, S., Vijgen, J., Di Biase, L. & Kirchhof, P. Circulation (2022). https://www.ncbi.nlm.nih.gov/pubmed/35135308  

Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques. Edsfeldt, A., Swart, M., Singh, P., Dib, L., Sun, J., Cole, J. E., Park, I., Al-Sharify, D., Persson, A., Nitulescu, M., Das Neves Borges, P., Kassiteridi, C., Goddard, M. E., Lee, R., Volkov, P., Orho-Melander, M., Maegdefessel, L., Nilsson, J., Udalova, I., Goncalves, I. et al. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35139193  

J wave syndromes in patients with spinal and bulbar muscular atrophy. Steinmetz, K., Rudic, B., Borggrefe, M., Muller, K., Siebert, R., Rottbauer, W., Ludolph, A., Buckert, D. & Rosenbohm, A. J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35132468  

Birth weight and heart failure: hindsight as an exact science? Fonseca, G., Garfias-Veitl, T. & von Haehling, S. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35134156  

Myogenic Vasoconstriction Requires Canonical Gq/11 Signaling of the Angiotensin II Type 1 Receptor. Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y. M., Schleifenbaum, J., Bader, M., Welsh, D. G., Huang, Y. & Gollasch, M. J Am Heart Assoc 11, e022070 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35132870  

Teleproctoring for Training in Structural Heart Interventions: Initial Real-World Experience During the COVID-19 Pandemic. Beyhoff, N., Zhu, M., Zanders, L., Leistner, D. M., Nobles, A., Schroeder, M., Barbieri, F., Landmesser, U. & Reinthaler, M. J Am Heart Assoc 11, e023757 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35132869  

[Drop in oxygen saturation and blood pressure as well as increase in central venous pressure during mitral valve clipping in an 81-year-old female patient]. Volz, M. J., Aurich, M., Konstandin, M., Katus, H. A., Frey, N., Kreusser, M. M. & Raake, P. W. Internist (Berl) (2022). https://www.ncbi.nlm.nih.gov/pubmed/35129621  

Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement. Sun, X., Hao, Y., Sebastian Kiekenap, J. F., Emeis, J., Steitz, M., Breitenstein-Attach, A., Berger, F. & Schmitt, B. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35129181  

Recommendations in pre-procedural imaging assessment for TAVI intervention: SIC-SIRM position paper part 2 (CT and MR angiography, standard medical reporting, future perspectives). Marano, R., Pontone, G., Agricola, E., Alushi, B., Bartorelli, A., Cameli, M., Carrabba, N., Esposito, A., Faletti, R., Francone, M., Galea, N., Golino, P., Guglielmo, M., Palmisano, A., Petronio, S., Petulla, M., Pradella, S., Ribichini, F., Romeo, F., Russo, V. et al. Radiol Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35129758  

Different Rates of Bioprosthetic Aortic Valve Failure With Perimount and Trifecta Bioprostheses. Lange, R., Alalawi, Z., Voss, S., Boehm, J., Krane, M. & Vitanova, K. Front Cardiovasc Med 8, 822893 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35127875  

Phosphodiesterases S-sulfhydration contributes to human skeletal muscle function. Vellecco, V., Panza, E., Bibli, S. I., Casillo, G. M., Raucci, F., Manzo, O. L., Smimmo, M., Villani, R., Cavezza, M. R., Fleming, I., d'Emmanuele di Villa Bianca, R., Maione, F., Cirino, G. & Bucci, M. Pharmacol Res 177, 106108 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35121122  

Stable patients with suspected myocardial ischemia: comparison of machine-learning computed tomography-based fractional flow reserve and stress perfusion cardiovascular magnetic resonance imaging to detect myocardial ischemia. Lossnitzer, D., Klenantz, S., Andre, F., Goerich, J., Schoepf, U. J., Pazzo, K. L., Sommer, A., Brado, M., Guckel, F., Sokiranski, R., Becher, T., Akin, I., Buss, S. J. & Baumann, S. BMC Cardiovasc Disord 22, 34 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35120459  

Generation of a CRISPR/Cas edited human induced pluripotent stem cell line DHMi005-A-1 carrying a patient-specific disease-causing point mutation in the TBX5 gene. Lahm, H., Heinrich, P., Zierler, E., Dzilic, E., Neb, I., Luzius, T., Doppler, S. A., Schneider, S., Lange, R., Krane, M. & Dressen, M. Stem Cell Res 60, 102691 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35121196  

Case Report: Cytomegalovirus Reactivation and Pericarditis Following ChAdOx1 nCoV-19 Vaccination Against SARS-CoV-2. Pluss, M., Mese, K., Kowallick, J. T., Schuster, A., Tampe, D. & Tampe, B. Front Immunol 12, 784145 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35116025  

Effects of sacubitril/valsartan versus valsartan on renal function in patients with and without diabetes and heart failure with preserved ejection fraction: insights from PARAGON-HF. Peikert, A., Vaduganathan, M., Mc Causland, F., Claggett, B. L., Chatur, S., Packer, M., Pfeffer, M. A., Zannad, F., Lefkowitz, M. P., Pieske, B., Dungen, H. D., McMurray, J. J. V. & Solomon, S. D. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35119183  

Early risk stratification in patients with cardiogenic shock irrespective of the underlying cause - the Cardiogenic Shock Score. Beer, B. N., Jentzer, J. C., Weimann, J., Dabboura, S., Yan, I., Sundermeyer, J., Kirchhof, P., Blankenberg, S., Schrage, B. & Westermann, D. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35119176  

Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels. S, O. B., Holmes, A. P., Johnson, D. M., Kabir, S. N., C, O. S., M, O. R., Avezzu, A., Reyat, J. S., Hall, A. W., Apicella, C., Ellinor, P. T., Niederer, S., Tucker, N. R., Fabritz, L., Kirchhof, P. & Pavlovic, D. J Mol Cell Cardiol 166, 23-35 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35114252  

Impact of thyroid dysfunction on short-term outcomes and long-term mortality in patients with pulmonary embolism. Pohl, K. R., Hobohm, L., Krieg, V. J., Sentler, C., Rogge, N. I. J., Steimke, L., Ebner, M., Lerchbaumer, M., Hasenfuss, G., Konstantinides, S., Lankeit, M. & Keller, K. Thromb Res 211, 70-78 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35114459  

Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor. Daugherty, A., Hegele, R. A., Lu, H. S., Mackman, N., Rader, D. J. & Weber, C. Arterioscler Thromb Vasc Biol, ATVBAHA122317426 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35109675  

Interactions Between Atrial Fibrillation and Natriuretic Peptide in Predicting Heart Failure Hospitalization or Cardiovascular Death. Brady, P. F., Chua, W., Nehaj, F., Connolly, D. L., Khashaba, A., Purmah, Y. J. V., Ul-Qamar, M. J., Thomas, M. R., Varma, C., Schnabel, R. B., Zeller, T., Fabritz, L. & Kirchhof, P. F. J Am Heart Assoc 11, e022833 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35112889  

Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators. Wesseler, F., Riege, D., Puthanveedu, M., Halver, J., Muller, E., Bertrand, J., Antonchick, A. P., Sievers, S., Waldmann, H. & Schade, D. J Med Chem (2022). https://www.ncbi.nlm.nih.gov/pubmed/35108017  

Diffusion-Weighted Imaging and Fluid-Attenuated Inversion Recovery Quantification to Predict Diffusion-Weighted Imaging-Fluid-Attenuated Inversion Recovery Mismatch Status in Ischemic Stroke With Unknown Onset. Scheldeman, L., Wouters, A., Dupont, P., Christensen, S., Boutitie, F., Cheng, B., Ebinger, M., Endres, M., Fiebach, J. B., Gerloff, C., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Thijs, V., Thomalla, G. & Lemmens, R. Stroke, STROKEAHA121036871 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35105179  

A quantitative RT-PCR protocol to adapt and quantify RBM20-dependent exon splicing of targets at the human locus. Rebs, S., Buchwald, T. A. & Streckfuss-Bomeke, K. STAR Protoc 3, 101117 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35106501  

Successfully implemented artificial intelligence and machine learning applications in cardiology: State-of-the-art review. Van den Eynde, J., Lachmann, M., Laugwitz, K. L., Manlhiot, C. & Kutty, S. Trends Cardiovasc Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35101642  

Prediction of risk for bleeding, myocardial infarction and mortality after percutaneous coronary intervention in patients with acute coronary syndromes. Ndrepepa, G., Neumann, F. J., Menichelli, M., Richardt, G., Cassese, S., Xhepa, E., Kufner, S., Lahu, S., Aytekin, A., Sager, H. B., Joner, M., Ibrahim, T., Muller, A., Fusaro, M., Hapfelmeier, A., Laugwitz, K. L., Schunkert, H., Kastrati, A. & Kasel, M. Coron Artery Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35102066  

Mental Health-Related Risk Factors and Interventions in Patients with Heart Failure. A Position Paper endorsed by the European Association of Preventive Cardiology (EAPC). Ladwig, K. H., Baghai, T. C., Doyle, F., Hamer, M., Herrmann-Lingen, C., Kunschitz, E., Lemogne, C., Beresnevaite, M., Compare, A., von Kanel, R., Sager, H. B. & Kop, W. J. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35104845  

Improved Quantification of Cell Density in the Arterial Wall-A Novel Nucleus Splitting Approach Applied to 3D Two-Photon Laser-Scanning Microscopy. van der Laan, K. W. F., Reesink, K. D., van der Bruggen, M. M., Jaminon, A. M. G., Schurgers, L. J., Megens, R. T. A., Huberts, W., Delhaas, T. & Spronck, B. Front Physiol 12, 814434 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35095571  

Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine. Schoger, E., Lelek, S., Panakova, D. & Zelarayan, L. C. Front Cardiovasc Med 8, 783072 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35097003  

Atrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration. Rivard, L., Friberg, L., Conen, D., Healey, J. S., Berge, T., Boriani, G., Brandes, A., Calkins, H., Camm, A. J., Yee Chen, L., Lluis Clua Espuny, J., Collins, R., Connolly, S., Dagres, N., Elkind, M. S. V., Engdahl, J., Field, T. S., Gersh, B. J., Glotzer, T. V., Hankey, G. J. et al. Circulation 145, 392-409 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35100023  

Coronary Artery Disease in Patients Presenting With Acute Ischemic Stroke or Transient Ischemic Attack and Elevated Troponin Levels. Kruska, M., Kolb, A., Fastner, C., Mildenberger, I., Hetjens, S., Kittel, M., Bail, K., Behnes, M., Akin, I., Borggrefe, M., Szabo, K. & Baumann, S. Front Neurol 12, 781553 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35095727  

Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures. Gonenc, II, Wolff, A., Schmidt, J., Zibat, A., Muller, C., Cyganek, L., Argyriou, L., Raschle, M., Yigit, G. & Wollnik, B. Hum Mol Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35099000  

Muscle Mass and Inflammation in Older Adults: Impact of the Metabolic Syndrome. Buchmann, N., Fielitz, J., Spira, D., Konig, M., Norman, K., Pawelec, G., Goldeck, D., Demuth, I. & Steinhagen-Thiessen, E. Gerontology, 1-10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35100595


Januar

Redox Regulatory Changes of Circadian Rhythm by the Environmental Risk Factors Traffic Noise and Air Pollution. Daiber, A., Frenis, K., Kuntic, M., Li, H., Wolf, E., Kilgallen, A. B., Lecour, S., Van Laake, L. W., Schulz, R., Hahad, O. & Munzel, T. Antioxid Redox Signal (2022). https://www.ncbi.nlm.nih.gov/pubmed/35088601

Association of thyroid function with insulin resistance: data from two population-based studies. Spira, D., Buchmann, N., Dorr, M., Markus, M. R. P., Nauck, M., Schipf, S., Spranger, J., Demuth, I., Steinhagen-Thiessen, E., Volzke, H. & Ittermann, T. Eur Thyroid J 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35085102  

Detection and analysis of cerebral aneurysms based on X-ray rotational angiography - the CADA 2020 challenge. Ivantsits, M., Goubergrits, L., Kuhnigk, J. M., Huellebrand, M., Bruening, J., Kossen, T., Pfahringer, B., Schaller, J., Spuler, A., Kuehne, T., Jia, Y., Li, X., Shit, S., Menze, B., Su, Z., Ma, J., Nie, Z., Jain, K., Liu, Y., Lin, Y. et al. Med Image Anal 77, 102333 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34998111  

Pulsed-field ablation combined with ultrahigh-density mapping in patients undergoing catheter ablation for atrial fibrillation: Practical and electrophysiological considerations. Gunawardene, M. A., Schaeffer, B. N., Jularic, M., Eickholt, C., Maurer, T., Akbulak, R. O., Flindt, M., Anwar, O., Pape, U. F., Maasberg, S., Gessler, N., Hartmann, J. & Willems, S. J Cardiovasc Electrophysiol 33, 345-356 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34978360

Circulating Interleukin-6 Levels and Incident Ischemic Stroke: A Systematic Review and Meta-analysis of Prospective Studies. Papadopoulos, A., Palaiopanos, K., Bjorkbacka, H., Peters, A., de Lemos, J. A., Seshadri, S., Dichgans, M. & Georgakis, M. K. Neurology 98, e1002-e1012 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34969940

Right atriotomy closure with modified ventricular assist device ring. Lanmuller, P., Eulert-Grehn, J. J., Starck, C., Falk, V. & Potapov, E. J Card Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35094449  

Evaluation of systemic inflammation in response to remote ischemic preconditioning in patients undergoing transcatheter aortic valve replacement (TAVR). Zhang, K., Troeger, W., Kuhn, M., Wiedemann, S., Ibrahim, K., Pfluecke, C., Sveric, K. M., Winzer, R., Fedders, D., Ruf, T. F., Strasser, R. H., Linke, A., Quick, S. & Heidrich, F. M. Rev Cardiovasc Med 23, 20 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092212  

Human-Device Interaction in the Life Science Laboratory. Soldner, R., Rheinlander, S., Meyer, T., Olszowy, M. & Austerjost, J. Adv Biochem Eng Biotechnol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35091814  

HFA-PEFF score: prognosis in patients with preserved ejection fraction after transcatheter aortic valve implantation. Seoudy, H., von Eberstein, M., Frank, J., Thomann, M., Puehler, T., Lutter, G., Lutz, M., Bramlage, P., Frey, N., Saad, M. & Frank, D. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092186  

Generation of homozygous Nav1.8 knock-out iPSC lines by CRISPR Cas9 genome editing to investigate a potential new antiarrhythmic strategy. Maurer, W., Hartmann, N., Argyriou, L., Sossalla, S. & Streckfuss-Bomeke, K. Stem Cell Res 60, 102677 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092938  

Progressive Hereditary Transthyretin-Related Amyloidosis (ATTRv) Aggravated by ATTR Wild-Type and Complement Activation. Mattig, I., Heidecker, B., Tschope, C., Messroghli, D., Eurich, D., Kleefeld, F., Gaedeke, J., Stenzel, W., Schmidt, H. H., Rocken, C., Knebel, F. & Hahn, K. J Neuropathol Exp Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092287  

Controlled-Level EVERolimus in Acute Coronary Syndrome (CLEVER-ACS) - A phase II, randomized, double-blind, multi-center, placebo-controlled trial. Klingenberg, R., Stahli, B. E., Heg, D., Denegri, A., Manka, R., Kapos, I., von Eckardstein, A., Carballo, D., Hamm, C. W., Vietheer, J., Rolf, A., Landmesser, U., Mach, F., Moccetti, T., Jung, C., Kelm, M., Munzel, T., Pedrazzini, G., Raber, L., Windecker, S. et al. Am Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092722 

Motion-compensated fat-water imaging for 3D cardiac MRI at ultra-high fields. Dietrich, S., Aigner, C. S., Mayer, J., Kolbitsch, C., Schulz-Menger, J., Schaeffter, T. & Schmitter, S. Magn Reson Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092090  

Telemedical cardiac risk assessment by implantable cardiac monitors in patients after myocardial infarction with autonomic dysfunction (SMART-MI-DZHK9): a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial. Bauer, A., Sappler, N., von Stulpnagel, L., Klemm, M., Schreinlechner, M., Wenner, F., Schier, J., Al Tawil, A., Dolejsi, T., Krasniqi, A., Eiffener, E., Bongarth, C., Stuhlinger, M., Huemer, M., Gori, T., Wakili, R., Sahin, R., Schwinger, R., Lutz, M., Luik, A. et al. Lancet Digit Health 4, e105-e116 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35090674  

A practical guide to setting up pig models for cardiovascular catheterization, electrophysiological assessment and heart disease research. Schuttler, D., Tomsits, P., Bleyer, C., Vlcek, J., Pauly, V., Hesse, N., Sinner, M., Merkus, D., Hamers, J., Kaab, S. & Clauss, S. Lab Anim (NY) 51, 46-67 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35087256  

Accuracy and Acute Efficacy of the Novel Injection-Based Occlusion Algorithm in Cryoballoon Pulmonary Vein Isolation Guided by Dielectric Imaging. Rottner, L., Moser, F., Weimann, J., Moser, J., Schleberger, R., Lemoine, M., Munkler, P., Dinshaw, L., Risius, T., Kirchhof, P., Ouyang, F., Reissmann, B., Metzner, A. & Rillig, A. Circ Arrhythm Electrophysiol 15, e010174 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089058  

Where the Action Is-Leukocyte Recruitment in Atherosclerosis. Mauersberger, C., Hinterdobler, J., Schunkert, H., Kessler, T. & Sager, H. B. Front Cardiovasc Med 8, 813984 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35087886  

[Ocular manifestations in patients with COVID-19]. Hosel, K., von der Burchard, C., Schunk, D., Franzenburg, J., Bahmer, T., Frank, D., Dargvainiene, J. & Roider, J. B. Ophthalmologe, 1-6 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089415  

Immune Mechanisms of Plaque Instability. Gerhardt, T., Haghikia, A., Stapmanns, P. & Leistner, D. M. Front Cardiovasc Med 8, 797046 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35087883  

Social Equity in the Efficacy of Computer-Based and In-Person Brief Alcohol Interventions Among General Hospital Patients With At-Risk Alcohol Use: A Randomized Controlled Trial. Freyer-Adam, J., Baumann, S., Bischof, G., Staudt, A., Goeze, C., Gaertner, B. & John, U. JMIR Ment Health 9, e31712 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089156  

Patterned Illumination Techniques in Optogenetics: An Insight Into Decelerating Murine Hearts. Diaz-Maue, L., Steinebach, J. & Richter, C. Front Physiol 12, 750535 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35087413  

Serum creatinine baseline fluctuation and acute kidney injury after intravenous or intra-arterial contrast agent administration - an intraindividual comparison as part of a randomized controlled trial. Bosserdt, M., Martus, P., Tauber, R., Dreger, H., Dewey, M. & Schonenberger, E. Nephrol Dial Transplant (2022). https://www.ncbi.nlm.nih.gov/pubmed/35090035  

Interpretation and actionability of genetic variants in cardiomyopathies: a position statement from the European Society of Cardiology Council on cardiovascular genomics. Arbustini, E., Behr, E. R., Carrier, L., van Duijn, C., Evans, P., Favalli, V., van der Harst, P., Haugaa, K. H., Jondeau, G., Kaab, S., Kaski, J. P., Kavousi, M., Loeys, B., Pantazis, A., Pinto, Y., Schunkert, H., Di Toro, A., Thum, T., Urtis, M., Waltenberger, J. et al. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089333  

Impact of inferior vena cava entry characteristics on tricuspid annular access during transcatheter interventions. Ranard, L. S., Vahl, T. P., Chung, C. J., Sadri, S., Khalique, O. K., Hamid, N., Nazif, T., George, I., Ng, V., Patel, A., Rezende, C. P., Reisman, M., Latib, A., Hausleiter, J., Sorajja, P., Bapat, V. N., Tang, G. H. L., Davidson, C. J., Zahr, F., Makkar, R. et al. Catheter Cardiovasc Interv (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084803  

Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive Cardiology. Piepoli, M. F., Adamo, M., Barison, A., Bestetti, R. B., Biegus, J., Bohm, M., Butler, J., Carapetis, J., Ceconi, C., Chioncel, O., Coats, A., Crespo-Leiro, M. G., de Simone, G., Drexel, H., Emdin, M., Farmakis, D., Halle, M., Heymans, S., Jaarsma, T., Jankowska, E. et al. Eur J Prev Cardiol 29, 275-300 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35083485  

Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells. Pavez-Giani, M. G. & Cyganek, L. Front Cell Dev Biol 9, 800529 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35083221   

Optimization of contrast material administration for coronary CT angiography using a software-based test-bolus evaluation algorithm. Fischer, A. M., Decker, J. A., Schoepf, J., Varga-Szemes, A., Flohr, T., Schmidt, B., Gutjahr, R., Sahbaee, P., Giovagnoli, D. A., Emrich, T., Martinez, J. D., Lari, K. B., Bayer, R. R., 2nd & Martin, S. S. Br J Radiol, 20201456 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084228  

Comparative analysis of common alignment tools for single-cell RNA sequencing. Bruning, R. S., Tombor, L., Schulz, M. H., Dimmeler, S. & John, D. Gigascience 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084033  

Human engineered heart tissue transplantation in a guinea pig chronic injury model. von Bibra, C., Shibamiya, A., Geertz, B., Querdel, E., Kohne, M., Studemann, T., Starbatty, J., Schmidt, F. N., Hansen, A., Hiebl, B., Eschenhagen, T. & Weinberger, F. J Mol Cell Cardiol 166, 1-10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35081367  

Cardiac fibroblast activation detected by (68)Gallium-FAPI-46 positron emission tomography-magnetic resonance imaging as a sign of chronic activity in cardiac sarcoidosis. Siebermair, J., Kessler, L., Kupusovic, J., Rassaf, T. & Rischpler, C. Eur Heart J Case Rep 6, ytac005 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35079689  

Real-time radial tagging for quantification of left ventricular torsion. Mohammadi, E., Nasiraei-Moghaddam, A. & Uecker, M. Magn Reson Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35081262  

Population-based cohort imaging: skeletal muscle mass by magnetic resonance imaging in correlation to bioelectrical-impedance analysis. Kiefer, L. S., Fabian, J., Rospleszcz, S., Lorbeer, R., Machann, J., Kraus, M. S., Fischer, M., Roemer, F., Rathmann, W., Meisinger, C., Heier, M., Nikolaou, K., Peters, A., Storz, C., Schlett, C. L. & Bamberg, F. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35080141  

Medication for patient-athletes-the therapeutic use exemption procedure. Fiorentini, C., Esefeld, K. & Halle, M. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35080612  

Trends and predictors of radiation exposure in percutaneous coronary intervention: the PROTECTION VIII study. Stocker, T. J., Abdel-Wahab, M., Mollmann, H., Deseive, S., Massberg, S. & Hausleiter, J. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/35076020  

Evaluation of a rapid deployment prosthesis strategy for the treatment of aortic valve endocarditis. Belyaev, S., Herrmann, F. E. M., Dashkevich, A., Wenke, K., Vlachea, P., von der Linden, J., Banafsche, R., Hagl, C. & Juchem, G. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35076056  

Myocardial Deformation in the Pediatric Age Group: Normal Values for Strain and Strain Rate Using 2D Magnetic Resonance Feature Tracking. Voges, I., Negwer, I., Caliebe, A., Boroni Grazioli, S., Daubeney, P. E. F., Uebing, A., Pennell, D. J. & Krupickova, S. J Magn Reson Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35072310  

Prognostic value of beta-blocker doses in patients with ventricular tachyarrhythmias. Schupp, T., Ziyadova, S., Reinhardt, J., Sag, Y. U., von Zworowsky, M., Reiser, L., Abumayyaleh, M., Weidner, K., Saleh, A., Mashayekhi, K., Bertsch, T., Abba, M. L., Akin, I. & Behnes, M. Heart Vessels (2022). https://www.ncbi.nlm.nih.gov/pubmed/35072762  

Exercise and Carotid Properties in the Young-The KiGGS-2 Study. Konigstein, K., Buschges, J. C., Sarganas, G., Krug, S., Neuhauser, H. & Schmidt-Trucksass, A. Front Cardiovasc Med 8, 767025 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35071349  

A cytosolic disulfide bridge-supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A. Voss, M., Kleinau, G., Gimber, N., Janek, K., Bredow, C., Thery, F., Impens, F., Schmoranzer, J., Scheerer, P., Kloetzel, P. M. & Beling, A. FEBS J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35066984  

Diagnostic Accuracy of High-Sensitive Troponin for the Identification of Myocardial Infarction in Patients Presenting with Acute Heart Failure. Ledwoch, J., Schneider, A., Leidgschwendner, K., Kraxenberger, J., Krauth, A., Schneider, V., Martens, E., Muller, A., Laugwitz, K. L. & Kupatt, C. J Emerg Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35065860  

Cascaded neural network-based CT image processing for aortic root analysis. Kruger, N., Meyer, A., Tautz, L., Hullebrand, M., Wamala, I., Pullig, M., Kofler, M., Kempfert, J., Sundermann, S., Falk, V. & Hennemuth, A. Int J Comput Assist Radiol Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35066774  

Disturbed lipid and amino acid metabolisms in COVID-19 patients. Masoodi, M., Peschka, M., Schmiedel, S., Haddad, M., Frye, M., Maas, C., Lohse, A., Huber, S., Kirchhof, P., Nofer, J. R. & Renne, T. J Mol Med (Berl), 1-14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35064792  

Prognostic value of epicardial adipose tissue volume in combination with coronary plaque and flow assessment for the prediction of major adverse cardiac events. Brandt, V., Bekeredjian, R., Schoepf, U. J., Varga-Szemes, A., Emrich, T., Aquino, G. J., Decker, J., Bayer, R. R., 2nd, Ellis, L., Ebersberger, U. & Tesche, C. Eur J Radiol 148, 110157 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35063819  

Tissue-specific multi-omics analysis of atrial fibrillation. Assum, I., Krause, J., Scheinhardt, M. O., Muller, C., Hammer, E., Borschel, C. S., Volker, U., Conradi, L., Geelhoed, B., Zeller, T., Schnabel, R. B. & Heinig, M. Nat Commun 13, 441 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35064145  

Tissue Engineered Transcatheter Pulmonary Valved Stent Implantation: Current State and Future Prospect. Zhang, X., Puehler, T., Seiler, J., Gorb, S. N., Sathananthan, J., Sellers, S., Haneya, A., Hansen, J. H., Uebing, A., Muller, O. J., Frank, D. & Lutter, G. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35054905  

Cardiohepatic Syndrome Is Associated With Poor Prognosis in Patients Undergoing Tricuspid Transcatheter Edge-to-Edge Valve Repair. Stolz, L., Orban, M., Besler, C., Kresoja, K. P., Braun, D., Doldi, P., Orban, M., Hagl, C., Rommel, K. P., Mayerle, J., Hausleiter, S., Low, K., Higuchi, S., Wild, M., Unterhuber, M., Massberg, S., Nabauer, M., Thiele, H., Lurz, P. & Hausleiter, J. JACC Cardiovasc Interv 15, 179-189 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35057989  

Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study. Metzner, T., Leitner, D. R., Mellitzer, K., Beck, A., Sourij, H., Stojakovic, T., Reishofer, G., Marz, W., Landmesser, U., Scharnagl, H., Toplak, H. & Silbernagel, G. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35052871  

Short-Term Treatment with Alirocumab, Flow-Dependent Dilatation of the Brachial Artery and Use of Magnetic Resonance Diffusion Tensor Imaging to Evaluate Vascular Structure: An Exploratory Pilot Study. Metzner, T., Leitner, D. R., Dimsity, G., Gunzer, F., Opriessnig, P., Mellitzer, K., Beck, A., Sourij, H., Stojakovic, T., Deutschmann, H., Marz, W., Landmesser, U., Brodmann, M., Reishofer, G., Scharnagl, H., Toplak, H. & Silbernagel, G. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35052831  

Increased Salt Intake Decreases Diet-Induced Thermogenesis in Healthy Volunteers: A Randomized Placebo-Controlled Study. Mahler, A., Klamer, S., Maifeld, A., Bartolomaeus, H., Marko, L., Chen, C. Y., Forslund, S. K., Boschmann, M., Muller, D. N. & Wilck, N. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35057434  

Association between thyroid function and assessment of hepatic fat and iron contents by magnetic resonance imaging. Ittermann, T., Khattak, R. M., Markus, M. R. P., Kuhn, J. P., Kromrey, M. L., Targher, G., Steveling, A., Nauck, M. & Volzke, H. Endocr Connect 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35060922   

Biomarkers-in-Cardiology 8 RE-VISITED-Consistent Safety of Early Discharge with a Dual Marker Strategy Combining a Normal hs-cTnT with a Normal Copeptin in Low-to-Intermediate Risk Patients with Suspected Acute Coronary Syndrome-A Secondary Analysis of the Randomized Biomarkers-in-Cardiology 8 Trial. Giannitsis, E., Garfias-Veitl, T., Slagman, A., Searle, J., Muller, C., Blankenberg, S., von Haehling, S., Katus, H. A., Hamm, C. W., Huber, K., Vollert, J. O. & Mockel, M. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35053326  

Aurora Kinase A Is Involved in Controlling the Localization of Aquaporin-2 in Renal Principal Cells. Baltzer, S., Bulatov, T., Schmied, C., Kramer, A., Berger, B. T., Oder, A., Walker-Gray, R., Kuschke, C., Zuhlke, K., Eichhorst, J., Lehmann, M., Knapp, S., Weston, J., von Kries, J. P., Sussmuth, R. D. & Klussmann, E. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35054947  

Hybrid Surgery for Severe Mitral Valve Calcification: Limitations and Caveats for an Open Transcatheter Approach. Bagaev, E., Ali, A., Saha, S., Sadoni, S., Orban, M., Naebauer, M., Mehilli, J., Massberg, S., Oberbach, A. & Hagl, C. Medicina (Kaunas) 58 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35056401  

Emerging Role of cAMP/AMPK Signaling. Aslam, M. & Ladilov, Y. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35053423  

Exercise-dependent changes in ventricular-arterial coupling and aortopulmonary collateral flow in Fontan patients: a real-time CMR study. Latus, H., Hofmann, L., Gummel, K., Khalil, M., Yerebakan, C., Waschulzik, B., Schranz, D., Voges, I., Jux, C. & Reich, B. Eur Heart J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35045176  

Association of Telomere Length With Risk of Disease and Mortality. Schneider, C. V., Schneider, K. M., Teumer, A., Rudolph, K. L., Hartmann, D., Rader, D. J. & Strnad, P. JAMA Intern Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35040871  

Stepwise approach for diagnosis and management of Takotsubo syndrome with cardiac imaging tools. Santoro, F., Mallardi, A., Leopizzi, A., Vitale, E., Stiermaier, T., Trambaiolo, P., Di Biase, M., Eitel, I. & Brunetti, N. D. Heart Fail Rev (2022). https://www.ncbi.nlm.nih.gov/pubmed/35040000  

MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium. Kremer, V., Bink, D. I., Stanicek, L., van Ingen, E., Gimbel, T., Hilderink, S., Gunther, S., Nossent, A. Y. & Boon, R. A. Sci Rep 12, 843 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35039572   

Does Age Matter? Pulmonary Endarterectomy in the Elderly Patient with CTEPH. Wiedenroth, C. B., Bandorski, D., Ariobi, K., Ghofrani, H. A., Lankeit, M., Liebetrau, C., Pruefer, D., Mayer, E., Kriechbaum, S. D. & Guth, S. Thorac Cardiovasc Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35038757  

Refining imaging tools to detect advanced fibrosis: could liver surface nodularity address an unmet need in the NAFLD epidemic? Schattenberg, J. M. & Emrich, T. Eur Radiol 32, 1757-1759 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084517  

Apolipoprotein E derived from CD11c(+) cells ameliorates atherosclerosis. Sauter, M., Sauter, R. J., Nording, H., Lin, C., Olbrich, M., Autenrieth, S., Gleissner, C., Thunemann, M., Otero, N., Lutgens, E., Aherrahrou, Z., Wolf, D., Zender, L., Meuth, S., Feil, R. & Langer, H. F. iScience 25, 103677 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35036868  

Additive value of epicardial adipose tissue quantification to coronary CT angiography-derived plaque characterization and CT fractional flow reserve for the prediction of lesion-specific ischemia. Brandt, V., Decker, J., Schoepf, U. J., Varga-Szemes, A., Emrich, T., Aquino, G., Bayer, R. R., 2nd, Carson, L., Sullivan, A., Ellis, L., von Knebel Doeberitz, P. L., Ebersberger, U., Bekeredjian, R. & Tesche, C. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35037968  

Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors. Becker, J., Stanifer, M. L., Leist, S. R., Stolp, B., Maiakovska, O., West, A., Wiedtke, E., Borner, K., Ghanem, A., Ambiel, I., Tse, L. V., Fackler, O. T., Baric, R. S., Boulant, S. & Grimm, D. Mol Ther (2022). https://www.ncbi.nlm.nih.gov/pubmed/35038579  

Prognostic impact of high-sensitive troponin on 30-day mortality in patients with acute heart failure and different classes of left ventricular ejection fraction. Ledwoch, J., Kraxenberger, J., Krauth, A., Schneider, A., Leidgschwendner, K., Schneider, V., Muller, A., Laugwitz, K. L., Kupatt, C. & Martens, E. Heart Vessels (2022). https://www.ncbi.nlm.nih.gov/pubmed/35034171  

Establishment of an induced pluripotent stem cell line DHMi005-A from a healthy male proband. Dressen, M., Luzius, T., Lahm, H., Neb, I., Doppler, S. A., Schneider, S., Dzilic, E., Lange, R. & Krane, M. Stem Cell Res 59, 102662 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35033855  

A junctional cAMP compartment regulates rapid Ca(2+) signaling in atrial myocytes. Brandenburg, S., Pawlowitz, J., Steckmeister, V., Subramanian, H., Uhlenkamp, D., Scardigli, M., Mushtaq, M., Amlaz, S. I., Kohl, T., Wegener, J. W., Arvanitis, D. A., Sanoudou, D., Sacconi, L., Hasenfuss, G., Voigt, N., Nikolaev, V. O. & Lehnart, S. E. J Mol Cell Cardiol 165, 141-157 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35033544  

Robustness of outcomes in trials evaluating sodium-glucose co-transporter 2 inhibitors for heart failure. Usman, M. S., Khan, M. S., Fonarow, G. C., Greene, S. J., Friede, T., Vaduganathan, M., Filippatos, G., Coats, A. J. S., Anker, S. D. & Butler, J. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35029056  

Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations. Rhoden, A., Schulze, T., Pietsch, N., Christ, T., Hansen, A. & Eschenhagen, T. Am J Physiol Heart Circ Physiol 322, H373-H385 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35030072   

[The new ESC guidelines 2021 on prevention of cardiovascular diseases : Appeal for prevention]. Fegers-Wustrow, I., Wimbauer, F. & Halle, M. Herz 47, 55-62 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35029736  

Assessment of frailty prior to TAVI: Can it now be measured objectively? Renker, M. & Kim, W. K. Int J Cardiol 350, 104-105 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35026339  

Endothelial Retargeting of AAV9 In Vivo. Bozoglu, T., Lee, S., Ziegler, T., Jurisch, V., Maas, S., Baehr, A., Hinkel, R., Hoenig, A., Hariharan, A., Kim, C. I., Decker, S., Sami, H., Koppara, T., Oellinger, R., Muller, O. J., Frank, D., Megens, R., Nelson, P., Weber, C., Schnieke, A. et al. Adv Sci (Weinh), e2103867 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35023328  

Low cardiopulmonary fitness is associated with higher liver fat content and higher gamma-glutamyltransferase concentrations in the general population - "The Sedentary's Liver". Zinterl, I., Ittermann, T., Schipf, S., Gross, S., Anspieler, H., Kim, S., Ewert, R., Bulow, R., Kuhn, J. P., Lerch, M. M., Volzke, H., Felix, S. B., Bahls, M., Targher, G., Dorr, M. & Markus, M. R. P. Liver Int (2022). https://www.ncbi.nlm.nih.gov/pubmed/35020966  

Acceptance and safety of femoral versus radial access for percutaneous coronary intervention (PCI): results from a large monitor-controlled German registry (QuIK). Reifart, J., Gohring, S., Albrecht, A., Haerer, W., Levenson, B., Ringwald, G., Gartner, P. & Reifart, N. BMC Cardiovasc Disord 22, 7 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35016644   

Meconium Microbiome of Very Preterm Infants across Germany. Klopp, J., Ferretti, P., Meyer, C. U., Hilbert, K., Haiss, A., Marissen, J., Henneke, P., Hudalla, H., Pirr, S., Viemann, D., Zemlin, M., Forslund, S. K., Hartel, C., Bork, P., Gehring, S., Van Rossum, T. & and the, P. C. mSphere 7, e0080821 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35019670   

Single-center experience of ultra-high-density mapping guided catheter ablation of focal atrial tachycardia. Kellnar, A., Fichtner, S., Mehr, M., Czermak, T., Sinner, M. F., Lackermair, K. & Estner, H. L. Clin Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35019172  

MicroRNA-365 regulates human cardiac action potential duration. Esfandyari, D., Idrissou, B. M. G., Hennis, K., Avramopoulos, P., Dueck, A., El-Battrawy, I., Gruter, L., Meier, M. A., Nager, A. C., Ramanujam, D., Dorn, T., Meitinger, T., Hagl, C., Milting, H., Borggrefe, M., Fenske, S., Biel, M., Dendorfer, A., Sassi, Y., Moretti, A. et al. Nat Commun 13, 220 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35017523  

Simultaneous [18F]fluoride and gadobutrol enhanced coronary positron emission tomography/magnetic resonance imaging for in vivo plaque characterization. Wurster, T. H., Landmesser, U., Abdelwahed, Y. S., Skurk, C., Morguet, A., Leistner, D. M., Frohlich, G., Haghikia, A., Engel, L. C., Schuster, A., Noutsias, M., Schulze, D., Hamm, B., Furth, C., Brenner, W., Botnar, R. M., Bigalke, B. & Makowski, M. R. Eur Heart J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35015852  

Synthesis of C-Oligosaccharides through Versatile C(sp(3) )-H Glycosylation of Glycosides. Wu, J., Kopp, A. & Ackermann, L. Angew Chem Int Ed Engl, e202114993 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35015329  

Skeletal muscle derived Musclin protects the heart during pathological overload. Szaroszyk, M., Kattih, B., Martin-Garrido, A., Trogisch, F. A., Dittrich, G. M., Grund, A., Abouissa, A., Derlin, K., Meier, M., Holler, T., Korf-Klingebiel, M., Volker, K., Garfias Macedo, T., Pablo Tortola, C., Boschmann, M., Huang, N., Froese, N., Zwadlo, C., Malek Mohammadi, M., Luo, X. et al. Nat Commun 13, 149 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35013221  

Education and certification on heart failure of the Heart Failure Association of the European Society of Cardiology. Mullens, W., Coats, A., Seferovic, P., Metra, M., Mebazaa, A., Ruschitzka, F., Filippatos, G., Volterrani, M., Ponikowski, P., Jankowska, E. A., Chioncel, O., McDonagh, T. A., Piepoli, M. F., Milicic, D., Thum, T., Hill, L., Abdelhamid, M., Adamopoulos, S., Belenkov, Y., Gal, T. B. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35014132  

Biodegradable Poly-epsilon-Caprolactone Scaffolds with ECFCs and iMSCs for Tissue-Engineered Heart Valves. Lutter, G., Puehler, T., Cyganek, L., Seiler, J., Rogler, A., Herberth, T., Knueppel, P., Gorb, S. N., Sathananthan, J., Sellers, S., Muller, O. J., Frank, D. & Haben, I. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35008953  

Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients. Haberbosch, L., Maurer, L., Sandforth, A., Wernicke, C., Spranger, J., Mai, K. & Jumpertz von Schwartzenberg, R. Endocr Relat Cancer 29, 121-128 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35014973  

[ESC guidelines 2021 on cardiac pacing and cardiac resynchronization therapy : What's new?]. Vogler, J., Keelani, A., Traub, A. & Tilz, R. R. Herz 47, 31-40 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35006289  

The Role of Junctophilin Proteins in Cellular Function. Lehnart, S. E. & Wehrens, X. H. T. Physiol Rev (2022). https://www.ncbi.nlm.nih.gov/pubmed/35001666  

First Transfemoral TAV-in-TAV Implantation of an ACURATE Neo2 Into a Degenerated Lotus Prosthesis. Kim, W. K., Charitos, E. I., Choi, Y. H. & Hamm, C. W. Can J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35007707  

Sparse 3D contrast-enhanced whole-heart imaging for coronary artery evaluation. Ansari, U., Janssen, S., Baumann, S., Borggrefe, M., Waldeck, S., Schonberg, S., Papavassiliu, T. & Overhoff, D. Herz (2022). https://www.ncbi.nlm.nih.gov/pubmed/35006290  

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart. van der Velden, J., Asselbergs, F. W., Bakkers, J., Batkai, S., Bertrand, L., Bezzina, C. R., Bot, I., Brundel, B., Carrier, L., Chamuleau, S., Ciccarelli, M., Dawson, D., Davidson, S. M., Dendorfer, A., Duncker, D. J., Eschenhagen, T., Fabritz, L., Falcao-Pires, I., Ferdinandy, P., Giacca, M. et al. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/34999816  

Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme. Petersen, E. L., Gossling, A., Adam, G., Aepfelbacher, M., Behrendt, C. A., Cavus, E., Cheng, B., Fischer, N., Gallinat, J., Kuhn, S., Gerloff, C., Koch-Gromus, U., Harter, M., Hanning, U., Huber, T. B., Kluge, S., Knobloch, J. K., Kuta, P., Schmidt-Lauber, C., Lutgehetmann, M. et al. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/34999762  

Polygenic Risk Scores for Predicting Adverse Outcomes After Coronary Revascularization. Aittokallio, J., Kauko, A., Vaura, F., Salomaa, V., Kiviniemi, T., FinnGen, Schnabel, R. B. & Niiranen, T. Am J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/34998506  

Effects of whole-body MRI on outpatient health service costs: a general-population prospective cohort study in Mecklenburg-Vorpommern, Germany. Schmidt, C. O., Sierocinski, E., Baumeister, S., Hegenscheid, K., Volzke, H. & Chenot, J. F. BMJ Open 12, e056572 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34996801  

Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension. Dahale, S., Ruiz-Orera, J., Silhavy, J., Hubner, N., van Heesch, S., Pravenec, M. & Atanur, S. S. Life Sci Alliance 5 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34996843  

Travelling with heart failure: risk assessment and practical recommendations. von Haehling, S., Birner, C., Dworatzek, E., Frantz, S., Hellenkamp, K., Israel, C. W., Kempf, T., Klein, H. H., Knosalla, C., Laufs, U., Raake, P., Wachter, R. & Hasenfuss, G. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/34992256  

Comparison of feasibility and results of frailty assessment methods prior to left ventricular assist device implantation. Roehrich, L., Sundermann, S. H., Just, I. A., Kopp Fernandes, L., Stein, J., Solowjowa, N., Mulzer, J., Mueller, M., Hummel, M., Knierim, J., Potapov, E., Falk, V. & Schoenrath, F. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/34994094  

The Gutenberg health study: a five-year prospective analysis of psychosocial working conditions using COPSOQ (Copenhagen psychosocial Questoinnaire) and ERI (effort-reward imbalance). Nuebling, M., Hegewald, J., Starke, K. R., Lincke, H. J., Jankowiak, S., Liebers, F., Latza, U., Letzel, S., Riechmann-Wolf, M., Gianicolo, E., Beutel, M., Pfeiffer, N., Lackner, K., Munzel, T., Wild, P. S. & Seidler, A. BMC Public Health 22, 24 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34991529  

Management of patients with mitral regurgitation ineligible for standard therapy undergoing TMVI screening. Ludwig, S., Sedighian, R., Weimann, J., Koell, B., Waldschmidt, L., Schafer, A., Seiffert, M., Westermann, D., Reichenspurner, H., Blankenberg, S., Schofer, N., Lubos, E., Conradi, L. & Kalbacher, D. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/34992049  

A Novel Transcatheter Heart Valve for an Overcrowded TAVR Market: What Should We Focus On? Lange, R. & Vitanova, K. JACC Cardiovasc Interv 15, 105-106 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34991815  

Evidence-based cardiovascular magnetic resonance cost-effectiveness calculator for the detection of significant coronary artery disease. Pandya, A., Yu, Y. J., Ge, Y., Nagel, E., Kwong, R. Y., Bakar, R. A., Grizzard, J. D., Merkler, A. E., Ntusi, N., Petersen, S. E., Rashedi, N., Schwitter, J., Selvanayagam, J. B., White, J. A., Carr, J., Raman, S. V., Simonetti, O. P., Bucciarelli-Ducci, C., Sierra-Galan, L. M., Ferrari, V. A. et al. J Cardiovasc Magn Reson 24, 1 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34986851  

Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome. Meier, A. B., Raj Murthi, S., Rawat, H., Toepfer, C. N., Santamaria, G., Schmid, M., Mastantuono, E., Schwarzmayr, T., Berutti, R., Cleuziou, J., Ewert, P., Gorlach, A., Klingel, K., Laugwitz, K. L., Seidman, C. E., Seidman, J. G., Moretti, A. & Wolf, C. M. iScience 25, 103596 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34988410  

Left atrial strain predicts exercise capacity in heart failure independently of left ventricular ejection fraction. Maffeis, C., Rossi, A., Cannata, L., Zocco, C., Belyavskiy, E., Radhakrishnan, A. K., Feuerstein, A., Morris, D. A., Pieske-Kraigher, E., Pieske, B., Edelmann, F. & Temporelli, P. L. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/34989138  

Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study. Gar, C., Thorand, B., Herder, C., Sujana, C., Heier, M., Meisinger, C., Peters, A., Koenig, W., Rathmann, W., Roden, M., Stumvoll, M., Maalmi, H., Meitinger, T., Then, H., Seissler, J. & Then, C. PLoS One 17, e0262330 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34990470  

Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure. Ceelen, D., Voors, A. A., Tromp, J., van Veldhuisen, D. J., Dickstein, K., de Boer, R. A., Lang, C. C., Anker, S. D., Ng, L. L., Metra, M., Ponikowski, P. & Figarska, S. M. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/34989084  

Early benefit with empagliflozin in heart failure with preserved ejection fraction: insights from the EMPEROR-Preserved trial. Butler, J., Siddiqi, T. J., Filippatos, G., Ferreira, J. P., Pocock, S. J., Zannad, F. & Anker, S. D. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/34989083  

"Precision-CT(O)": CTO-lesions unraveled by multimodality cardiac imaging. Abdelwahed, Y. S., Blum, E., Landmesser, U., Werner, G. S. & Leistner, D. M. Int J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/34982310  

Implication of proliferation gene biomarkers in pulmonary hypertension. Yan, Y., Jiang, R., Yuan, P., Wen, L., Pang, X. B., Jing, Z. C., He, Y. Y. & Han, Z. Y. Animal Model Exp Med 4, 369-380 (2021). https://www.ncbi.nlm.nih.gov/pubmed/34977488 

Anatomical suitability and off-label use of contemporary transcatheter heart valves. Werner, N., Renker, M., Dorr, O., Bauer, T., Nef, H., Choi, Y. H., Hamm, C. W., Zahn, R. & Kim, W. K. Int J Cardiol 350, 96-103 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34979147  

State-of-the-art: Insights from the Ross Registry. Fujita, B., Aboud, A., Sievers, H. H. & Ensminger, S. JTCVS Tech 10, 396-400 (2021). https://www.ncbi.nlm.nih.gov/pubmed/34977764  

The year in cardiovascular medicine 2021: interventional cardiology. Escaned, J., Jaffer, F. A., Mehilli, J. & Mehran, R. Eur Heart J 43, 377-386 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34974613  

Circulating Interleukin-6 Levels and Incident Ischemic Stroke: A Systematic Review and Meta-analysis of Prospective Studies. Papadopoulos, A., Palaiopanos, K., Bjorkbacka, H., Peters, A., de Lemos, J. A., Seshadri, S., Dichgans, M. & Georgakis, M. K. Neurology (2021). https://www.ncbi.nlm.nih.gov/pubmed/34969940  

Histopathology-Based Deep-Learning Predicts Atherosclerotic Lesions in Intravascular Imaging. Holmberg, O., Lenz, T., Koch, V., Alyagoob, A., Utsch, L., Rank, A., Sabic, E., Seguchi, M., Xhepa, E., Kufner, S., Cassese, S., Kastrati, A., Marr, C., Joner, M. & Nicol, P. Front Cardiovasc Med 8, 779807 (2021). https://www.ncbi.nlm.nih.gov/pubmed/34970608  

PET/MR Technology: Advancement and Challenges. Bogdanovic, B., Solari, E. L., Villagran Asiares, A., McIntosh, L., van Marwick, S., Schachoff, S. & Nekolla, S. G. Semin Nucl Med (2021). https://www.ncbi.nlm.nih.gov/pubmed/34969520  

Remote Speech Analysis in the Evaluation of Hospitalized Patients With Acute Decompensated Heart Failure. Amir, O., Abraham, W. T., Azzam, Z. S., Berger, G., Anker, S. D., Pinney, S. P., Burkhoff, D., Shallom, I. D., Lotan, C. & Edelman, E. R. JACC Heart Fail 10, 41-49 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34969496