Diagnosis and risk stratification of patients with cardiomyopathy

To improve diagnosis and risk stratification of patients with cardiomyopathy, this project assesses secretome biomarker profiles via proteomic analysis methods.

 - Diagnosis and risk stratification of patients with cardiomyopathy

The DZHK biospecimen from patients with dilated or hypertrophic cardiomyopathy (DCM/HCM) enable the validation of common biomarkers from DCM/HCM patients in human iPSC-derived cardiomyocytes from patients with DCM/HCM mutations. These studies may support the development of future therapeutic and diagnostic approaches. A better understanding of the molecular mechanisms in cardiomyopathy via profiling of secreted biomarkers could facilitate future diagnostics and therapies for patients with cardiomyopathy.

Publications

There are no publications available yet.

Project Term
06/2023 - 06/2025
Granted Budget
€ 40.000
Research resource used
Resource liquid samples/image data
Keywords
cardiomyopathy, biomarker, iPSC-cardiomyocytes