Facilitating International Clinical Trials

The following notes explain the steps in the diagram (red: steps at the DZHK, blue: steps at the GCRFF).
 

3

Preliminary administrative check of the EOI
The eligibility to apply is checked here. The deadline is 17 days before an EOI submission at the latest. Please send the EOI to clinicalstudies@dzhk.de (Clinical Research Group). The formal check includes three aspects:

•    Is the scientist basically established in the DZHK and eligible to apply?
•    Does the EOI comply with the rules of the DZHK funding guideline for guideline-relevant studies? 
•    Are there any overlaps with a DZHK-funded study?

If the formal preliminary check is positive, the EOI including the formally confirmed application authorisation can be submitted to the GCRFF. If the check is not positive, another German funding organisation must be approached for the German part of the study.
Note: A successful formal preliminary check is no guarantee for funding by the DZHK. The DZHK will only fund the German part of the study once a full application has been approved by the Research Coordinating Committee (RCC) (see step 10), the funding law review has been completed and the financing of the entire study has been confirmed.

4

Submit EOI to the GCRFF

The current deadlines can be found at www.bhf.org.uk
The EOI is submitted via the Grants Management System of the British Heart Foundation (BHF).

6

Submit a full application to the Clinical Study Group (CSG) of the DZHK

If the GCRFF has endorsed the study, a full application can be submitted to the Clinical Study Group (CSG) of the DZHK. The CSG will review the full application in the regular procedure. Here you will find the next deadline, information and application documents (DZHK intranet, login required) for a full application.
Note: An endorsement by the GCRFF is no guarantee for funding by the DZHK - but it improves the chances that the German part of the study will be funded by the DZHK.

7

Clinical pitch

The study will be presented to the DZHK clinicians in a short clinical pitch to test the feasibility in DZHK Study Units.

8

Further documents

If there are already positive review results from comparable public funding organisations (e.g. from other funders participating in the GCRFF) for the proposed study design, please submit the complete review documents to us together with the full application.

9

CSG review

The CSG reviews and ranks the full proposal in comparison to other full proposals for guideline-relevant studies.

10

Proof of overall funding

In addition, the implementation of the funding intention is conditional on the funding of the overall international study. This must be demonstrated within 9 months. 

The following notes explain the steps in the diagram (red: steps at the DZHK, blue: steps at the GCRFF).

C-E

Submission to the CSG

The submission of the EOI to the GCRFF requires a favourable consultation by the CSG. Please use the deadline for short applications for guideline-relevant studies (GRS) of the DZHK to first present the EOI to the DZHK as potential funder of the study centre and obtain approval for submission. Prior to submission to the GCRFF, the CSG assesses the short application (equivalent in content to an EOI draft) in comparison with other applications for guideline-relevant studies and, if applicable, approves it as promising. The aim is to select promising EOIs (lead in the DZHK) in advance and to propose them to the GCRFF from within the DZHK.
Note: A successful pre-selection by the CSG is no guarantee for funding by the DZHK. The DZHK will only fund the German part of the study once a full application has been approved by the Research Coordinating Committee (RCC) (see step J), the funding law review has been completed and the financing of the entire study has been confirmed.

D

Clinical pitch

The study will be presented to the DZHK clinicians in a short clinical pitch to test its feasibility in DZHK Study Units.

F

Submit EOI to the GCRFF

You can find the current deadlines at www.bhf.org.uk
The EOI is submitted via the Grants Management System of the British Heart Foundation (BHF).

H-J

Submit a full application to the Clinical Study Group (CSG) of the DZHK

If the GCRFF has endorsed the study, a full application can be submitted to the Clinical Study Group (CSG) of the DZHK. The CSG will review the full application in the regular procedure. Here you can find the next deadline, information and application documents (DZHK intranet, login required) for a full application.
Note: An endorsement by the GCRFF is no guarantee for funding by the DZHK - but it improves the chances that the German part of the study will be funded by the DZHK.

I

Submit further assessment results

If there are already positive review results from comparable public funding organisations (e.g. from other funders participating in the GCRFF) for the study design applied for, please submit the complete review documents to us together with the full application. The CSG evaluates and ranks the full proposal in comparison to other full proposals for guideline-relevant studies.

J

Proof of overall funding

In addition, the realisation of the funding intention is conditional on the funding of the overall international study. This must be proven within 9 months.

If you are not a member of the DZHK, and are therefore not eligible to apply for funding from the DZHK, you should plan to apply for national funding for the German component of your study, for example from the Federal Ministry of Education and Research (BMBF) or the German Research Foundation (DFG).

The EOI is submitted via the Grants Management System der British Heart Foundation (BHF) .