Data and Biospecimens

The DZHK Heart Bank contains extensive cardiovascular resources. These include high-quality clinical data, image data, OMICs data, as well as liquid and tissue biospecimens, including the associated data, which are processed and stored reliably and under standardized conditions. This creates an essential prerequisite for reproducible research results.

Introducing our resources:

Resource with Liquid Biospecimens and Image Data

  • Liquid Biospecimens (serum, EDTA plasma, citrate plasma, buffy coat, urine)
  • Patient records with a wide range of cardiac diagnoses
  • Image data (ECG, echo)

All liquid biospecimens with associated clinical data and image data come from DZHK-funded studies that are obtained using standardized procedures at all study centers via the DZHK's research platform. As a result, our resource is growing steadily.

For more information, visit the resource with liquid biospecimen and image data.

Cardiovascular Tissue Specimen Resource

  • 6,000 Tissue Biospecimens
  • EDTA blood and untreated PAXGene samples
  • Associated Clinical Data

This resource currently contains more than 6,000 tissue biospecimens from 3,000 cardiac heart diagnosed patients collected at the German Heart Center Berlin facility. In addition, liquid biospecimens of EDTA blood (plasma, whole blood, cellular blood components) and unprocessed PAXGene samples are available. Our biospecimens are collected in a standardized manner and provided with the associated clinical data.

For more information, visit the facility, Deutsches Herzzentrum Berlin.

DZHKomics Resource (DNA und RNA)

  • 1,200 genetic records from healthy individuals
  • 1,150 whole genome sequences
  • 700 RNA sequences

This control resource was generated from around 1,200 healthy people. It serves as a basis of comparison for the more precise determination of differences between healthy and sick people - not only for cardiovascular research. Approximately 1,150 whole genome sequences consist of SNVs, Indels and approx. 48 million variants. In addition, there are RNA sequence data from around 700 test persons. Corresponding basic phenotypes are also available.

For more information, visit the DZHKomics resource.