Paper of the Month

 

With the Paper of the month the Board of Directors rewards a recent scientific publication of DZHK researchers.

 

 

Cell-intrinsic effects of clonal hematopoiesis in heart failure. Nature Cardiovascular Research (2023)

DZHK authors: Wesley T. Abplanalp, Sebastian Cremer, Maximilian Merten, Mariana Shumliakivska, Igor Macinkovic, Andreas M. Zeiher, David John & Stefanie Dimmeler

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Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. The New England Journal of Medicine (2023)

DZHK authors: Christine Magnussen, Marcus Dörr, Anette Peters, Raphael Twerenbold, Philipp S. Wild, Andreas Ziegler, Stefan Blankenberg, Wolfgang König, Karl J. Lackner, David M. Leistner, Thiess Lorenz, Julia Waibel

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Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease. Science (2023)

DZHK authors: Karin A. Ziegler, Anne Dueck, Dena Esfandyari, Pauline Pichler, Karolin Weber, Alexander Bartelt, Ludwig Weckbach, Steffen Massberg, Gabriele Schiatteralla, Stefan Engelhardt

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Cardiomuscular Biomarkers in the Diagnosis and Prognostication of Immune Checkpoint Inhibitor Myocarditis. Circulation (2023)

DZHK authors: Lorenz H. Lehmann, Markus B. Heckmann, Daniel Finke, Frederic Stein, Jan Münster, Hugo A. Katus, Evangelos Giannitsis, Norbert Frey, Ziya Kaya

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The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Immunity (2023)

DZHK authors: Giorgia Ciliberti, Jedrzej Hoffmann, Andre Schneider, Stefan Guenther, Johannes Backs, Thomas Braun, Stefanie Dimmeler, Markus Sperandio, Konstantinos Stellos

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The Board of Directors has selected two publications as the Paper of the Month for April:

To the publications

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The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies. Clinical Research in Cardiology (2023)

DZHK authors: Julia Hoffmann, Sabine Hanss, Monika Kraus, Jens Schaller, Christian Schäfer, Dana Stahl

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Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation. Nature Cardiovascular Research (2022)

DZHK authors: Carina Mauersberger, Hendrik Sager, Tan An Dang, Laura Lambrecht, Heribert Schunkert, Thorsten Kessler

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Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-beta1 driven fibrotic remodeling in ischemic heart failure (J Clin Invest 2022)

DZHK authors: V. Garlapati, M. Molitor, S. Finger, J. Wild, S. Karbach, T. Münzel, A. Daiber, M. Brandt, T. Gori, S. Tenzer, W. Ruf, P. Wenzel

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Lamin A/C-dependent chromatin architecture safeguards naive pluripotency to prevent aberrant cardiovascular cell fate and function. Nature Communications (2022)

DZHK authors: Yinuo Wang, Julio Cordero, Haojie Shi, Felix Trogisch, Mona Malek Mohammadi, Johannes Backs, Thomas Wieland, Jörg Heineke, Gergana Dobreva

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