Paper of the Month

 

With the Paper of the month the Board of Directors rewards a recent scientific publication of DZHK researchers.

 

 

Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-beta1 driven fibrotic remodeling in ischemic heart failure (J Clin Invest 2022)

DZHK authors: V. Garlapati, M. Molitor, S. Finger, J. Wild, S. Karbach, T. Münzel, A. Daiber, M. Brandt, T. Gori, S. Tenzer, W. Ruf, P. Wenzel

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Lamin A/C-dependent chromatin architecture safeguards naive pluripotency to prevent aberrant cardiovascular cell fate and function. Nature Communications (2022)

DZHK authors: Yinuo Wang, Julio Cordero, Haojie Shi, Felix Trogisch, Mona Malek Mohammadi, Johannes Backs, Thomas Wieland, Jörg Heineke, Gergana Dobreva

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NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart. Nature Communications (2022)

DZHK authors: Marion Müller, Rose Eghbalian, Karen S. Frese, Jan Haas, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Maximilian K. Lackner, Oguz F. Tugrul, Rewati Tappu, Diana Martins Bordalo, Sarah Schudy, Hugo A. Katus, Norbert Frey, Lars M. Steinmetz, Benjamin Meder

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Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury. Circulation (2022)

DZHK-authors: Tim Stüdemann, Judith Rössinger, Christoph Manthey, Rajiven Srikantharajah, Constantin von Bibra, Aya Shibamiya, Maria Köhne, Thomas Eschenhagen, Florian Weinberger

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Smartphone-based screening for atrial fibrillation: a pragmatic randomized clinical trial. Nature Medicine (2022)

DZHK authors: Konstantinos Rizas, Lukas von Stülpnagel, Mathias Klemm, Steffen Massberg

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Origin and function of activated fibroblast states during zebrafish heart regeneration. Nature Genetics (2022)

DZHK authors: Bo Hu, Sara Lelek, Bastiaan Spanjaard, Hadil El-Sammak, Mariana Guedes Simões, Janita Mintcheva, Hananeh Aliee, Ronny Schäfer, Alexander M. Meyer, Fabian Theis, Didier Y. R. Stainier, Daniela Panáková & Jan Philipp Junker

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A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth. Nature Metabolism (2022)

DZHK authors: Marco Castro, Toshiya Sugino, Kerstin Wilhelm, Stefan Guenther, André Schneider, Thomas Braun, Holger Gerhardt, Michael Potente

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Neuroimmune cardiovascular interfaces control atherosclerosis. Nature (2022)

DZHK-authors: Sarajo K. Mohanta, Donato Santovito, Remco T. A. Megens, Sabine Steffens, Jürgen Bernhagen, Changjun Yin, Christian Weber, Andreas J. R. Habenicht

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Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Hypertension (2022)

DZHK authors: Pedro Felipe Malacarne, Corina Ratiu, Niklas Müller, Melina Lopez, Beatrice Pflüger-Müller, Timothy Warwick, James Oo, Mauro Siragusa, Ingrid Fleming, Ralf P. Brandes, Flávia Rezende

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Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection. Nature Communications (2022)

DZHK authors: Kami Pekayvaz, Alexander Leunig, Rainer Kaiser, Clemens Scherer, Kathrin Saar, Lukas Tomas, Christian Schulz, Norbert Hubner, Steffen Massberg, Konstantin Stark, Leo Nicolai

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