Paper of the Month

DZHK authors: Luka Nicin, Sam Michael Schroeter, Simone Franziska Glaser, Susanne S. Hille, Badder Kattih, Wesley Tyler Abplanalp, Lukas Tombor, Oliver J. Müller, Thomas Braun, Benjamin Meder, Christoph Reich, Thomas Walther, Jaya Krishnan, Andreas M. Zeiher, David John & Stefanie Dimmeler

DZHK-authors: Julia Krause, Markus O. Scheinhardt, Christian Müller, Elke Hammer, Christin S. Börschel, Uwe Völker, Lenard Conradi, Bastiaan Geelhoed, Tanja Zeller, Renate B. Schnabel & Matthias Heinig

Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue. Science Translational Medicine (2021) 13, 8952. DZHK authors: Michael Radke, Victor Badillo-Lisakowski, Thiago Britto-Borges, Pragati Parakkat, Judith Hüttemeister, Martin Liss, Arne Hansen, Christoph Dieterich, Michael Gotthardt.

Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization. Circulation. 2021 Nov 9;144(19):1567-1583. DZHK authors: Francesca Fasolo, Jessica Pauli, Hanna Winter, Sabine Bauer, Susanne Metschl, Hans-Henning Eckstein, Oliver Soehnlein, Valentina Paloschi, Lars Maegdefessel

Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice, DZHK authors: Eric Schoger, Laura C. Zelarayán, Johnny Kim, Thomas Braun, Science, 24 September 2021

Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis, Circulation: Genomic and Precision Medicine. 2021;14:e003250, DZHK authors: Franziska Seidel, Nadya Al-Wakeel-Marquard, Daniel Messroghli, Felix Berger, Stephan Schubert, Jirko Kühnisch, Sabine Klaassen

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation. DZHK authors: Friederike Cuello, Umber Saleem, Malte Loos, Janice Raabe, Sandra Laufer, Bärbel M Ulmer, Ingke Braren, Norbert Hübner, Thomas Eschenhagen, Arne Hansen

Epigenetic gene expression links heart failure to memory impairment. EMBO Mol Med (2021). DZHK authors: Anke Zieseniss, Dörthe Magdalena Katschinski, Karl Toischer, Andre Fischer

Exercise-Stress Real-time Cardiac Magnetic Resonance Imaging for Non-Invasive Characterisation of Heart Failure with Preserved Ejection Fraction: The HFpEF Stress Trial. Circulation. 2021 Jan 21. DZHK authors: Sören J. Backhaus, Torben Lange, Elisabeth F. George, Kristian Hellenkamp, Marcus Billing, Rolf Wachter, Michael Steinmetz, Uwe Raaz, Joachim Lotz, Tim Friede, Martin Uecker, Gerd Hasenfuß, Tim Seidler, Andreas Schuster

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study. European Heart Journal (2020), DZHK authors: David M Leistner, Nicolle Kränkel, Denitsa Meteva, Youssef S Abdelwahed , Claudio Seppelt , Barbara E Stähli , Himanshu Rai, Carsten Skurk , Alexander Lauten, Georg Fröhlich, Ursula Rauch-Kröhnert, Matthias Riedel, Lara Sieronsk, Sylvia Kia, Elisabeth Strässler, Arash Haghikia, Fabian Dirks, Julia K Steiner, Dominik N Mueller, Michael Jone, Ulf Landmesser