SFB/TR19plus (Fortführung der Kohorte “Inflammatorische Kardiomyopathie” des Sonderforschungsbereichs Transregio 19 (SFB/TR19) als “SFB/TR19 Plus”)

Inflammatory diseases of the heart muscle (inflammatory cardiomyopathies) can lead to pathological enlargement of the heart and heart failure, which in turn is one of the most common causes of death among cardiovascular diseases. To investigate, among other aspects, the development of inflammatory heart muscle diseases, the Collaborative Research Centre/Transregio 19 (SFB/TR19) funded by the German Research Foundation (DFG) established the “Inflammatory Cardiomyopathy” cohort (recruitment 2005–2014).

The aim of the research is to develop new approaches for the diagnosis and treatment of inflammatory cardiomyopathies by analysing patient data and biological material.

This original patient cohort was continued in the associated DZHK study “SFB/TR19 Plus” (recruitment 2015–2025). Within this framework, follow-up examinations were conducted, allowing biological samples and data on long-term outcomes to be collected continuously. The data were collected in an analogous manner to the registry TORCH-DZHK1, using the infrastructure of the DZHK. The cohort includes biospecimens and data with long-term follow-up, as well as regularly updated mortality data.

Through the SFB/TR19 Transfer Office in Greifswald, the data from the first cohort and the subsequent follow-up examinations from “SFB/TR19 Plus” will soon be available for joint application. Email: sfbtr19-transfer@med.uni-greifswald.de

Principal Investigators

Principal investigator: Marcus Dörr (Greifswald)