Clinical Studies

Sortierung
Suchen und filtern

 Studies

Prediction of Acute Coronary Syndrome in Acute Ischemic Stroke (PRAISE-DZHK19 I DZNE 001)

The aim of the study PRAISE-DZHK19 I DZNE B001 is to establish a clinical algorithm that enables the prediction of acute coronary syndrome or heart attack in stroke patients.

Recruiting status
Recruiting ongoing
Principal Investigators
Matthias Endres, Ulf Landmesser, Christian Nolte (Berlin)
10/2018 251 EUR 542.644,91 Berlin,Leipzig,Greifswald,Hamburg,Lübeck,Fulda,Göttingen,Osnabrück,Bonn,Frankfurt am Main,Mannheim,Heidelberg,Tübingen,München,Erlangen,Celle,Bad Neustadt,Dresden Frühe klinische Studie Schlaganfall

Effect of Metformin in insulin resistant patients with heart failure with reduced ejection fraction (METRIS-HF-DZHK18)

The METRIS-HF-DZHK18 trial aims to find out whether improved energy metabolism can increase heart efficiency in patients with cardiac insufficiency.

Recruiting status
Recruiting ongoing
Principal Investigators
Wolfram Döhner (Berlin), Burkert Pieske (Berlin), Tim Friede (Göttingen)
09/2018 88 EUR 973.012,80 Berlin Frühe klinische Studie Herzschwäche

Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Older (SCREEN AF-DZHK15)

The SCREEN-AF study aims to improve the early detection of atrial fibrillation using a new “rhythm patch” with an integrated ECG recording unit which is applied to the patient’s chest.

Recruiting status
Recruiting complete, follow-up continuing
Principal Investigators
Rolf Wachter, Eva Hummers-Pradier (Göttingen), Jeff Healey, David Gladstone (Canadian Stroke Prevention Intervention Network, Kanada)
12/2017 267 EUR 725.674,19 Göttingen,Hamburg Leitlinien-relevante Studie Vorhofflimmern

Evaluating the benefit of concurrent tricuspid valve repair during mitral surgery (CTSN-TVR-DZHK14)

The aim of the study is to clarify whether it is beneficial to operate the tricuspid valve in the right heart at the same time if the mitral valve is defective, even if the right heart valve is not yet very leaky.

Recruiting status
Recruiting complete, follow-up continuing
Principal Investigators
Volkmar Falk (Berlin); Annetine C. Gelijns (Icahn School of Medicine at Mount Sinai, NY, USA)
06/2017 76 EUR 895.351 Berlin,Leipzig,Jena,Hamburg,Lübeck,Bad Oeynhausen,Göttingen,Frankfurt am Main,Bad Krozingen,München Leitlinien-relevante Studie Herzklappenerkrankungen

Validation of Cardiovascular Magnetic Resonance against Invasive Haemodynamics in Patients with Heart Failure with Preserved Ejection Fraction (Decipher HFpEF-DZHK12)

The DECIPHER HFpEF-DZHK12 study investigates whether diastolic heart failure can be better diagnosed and its causes clarified with the help of cardiovascular magnetic resonance imaging (CMR).

Recruiting status
Recruiting ongoing
Principal Investigators
Eike Nagel (Frankfurt)
01/2018 185 EUR 811.793,58 Frankfurt am Main,Berlin,Heidelberg,Göttingen,Mainz Frühe klinische Studie Herzschwäche

Exercise Training in Patients with Left Ventricular Assist Device (Ex-VAD-DZHK11)

  1. This study is examining whether a tailored physical exercise can improve the fitness and quality of life of patients with an artificial heart.

Recruiting status
Recruiting ongoing
Principal Investigators
Frank Edelmann (Berlin), Burkert Pieske (Berlin), Martin Halle (München), Volkmar Falk (Berlin)
12/2017 66 EUR 640.523,21 Berlin,Leipzig,Hamburg,Düsseldorf,München Frühe klinische Studie Herzschwäche

Randomized Trial of TAVI versus SAVR in Patients with Symptomatic Severe Aortic Valve Stenosis and Intermediate Risk of Mortality (DEDICATE-DZHK6)

The DEDICATE-DZHK6 study is investigating whether surgical or transcatheter aortic valve implantation is the superior long-term treatment option for patients with severe aortic valve stenosis.

Recruiting status
Recruiting ongoing
Principal Investigators
Stefan Blankenberg, Moritz Seiffert (Hamburg)
05/2017 1600 EUR 3.966.680,61 Hamburg,Dresden,Leipzig,Jena,Berlin,Lübeck,Kiel,Hannover,Bad Oeynhausen,Gießen,Göttingen,Düsseldorf,Bochum,Münster,Köln,Aachen,Mainz,Bad Nauheim,Heidelberg,Stuttgart,Bad Krozingen,München,Ulm,Erlangen,Regensburg,Bad Neustadt,Frankfurt am Main,Halle (Saale) Leitlinien-relevante Studie Herzschwäche

Ultrasound evaluation of the inferior vena cava in addition to clinical assessment to guide decongestion in acute decompensated heart failure: a pilot study (CAVA-ADHF-DZHK10)

This trial is examining whether an ultrasound evaluation of the inferior vena cava in acute decompensated heart failure (ADHF) with congestion can be implemented in hospitals’ everyday routine in a large number of patients.

Recruiting status
Recruiting ongoing
Principal Investigators
Alexander Jobs (Lübeck), Holger Thiele
07/2017 388 EUR 1.097.524,51 Lübeck,Leipzig,Berlin,Greifswald,Hamburg,Kiel,Göttingen,Mainz,Frankfurt am Main,Mannheim,München,Würzburg Frühe klinische Studie Herzschwäche

Cardiovascular magnetic resonance real time exercise stress testing in heart failure with preserved ejection fraction (HFpEF-stress-DZHK17)

Researchers will test in this trial whether the newly developed real-time CMR technology is suitable for the early and safe diagnosis of HFpEF.

Recruiting status
Recruiting ongoing
Principal Investigators
Andreas Schuster (Göttingen)
08/2017 70 EUR 317.879,99 Göttingen Frühe klinische Studie Herzschwäche

Left atrial appendage CLOSURE in patients with Atrial Fibrillation at high risk of stroke and bleeding compared to medical therapy (CLOSURE-AF-DZHK16)

The DZHK study CLOSURE-AF compares the benefit of the left atrial appendage closure with the best possible drug therapy for high-risk patients with atrial fibrillation.

Recruiting status
Recruiting ongoing
Principal Investigators
Ulf Landmesser (Berlin), Ingo Eitel (Lübeck), Leif-Hendrik Boldt (Berlin)
03/2018 1512 EUR 6.972.940,28 Berlin,Dresden,Leipzig,Gera,Jena,Zwickau,Chemnitz,Brandenburg,Hennigsdorf,Greifswald,Rostock,Hamburg,Lübeck,Kiel,Heide,Bremen,Herford,Detmold,Gießen,Fulda,Göttingen,Wuppertal,Essen,Mainz,Frankfurt am Main,Kaiserslautern,Mannheim,Heidelberg,Tübingen,Freudenstadt,Villingen-Schwenningen,Bad Krozingen,München,Dachau,Ulm,Erlangen,Coburg,Würzburg,Erfurt,Halle (Saale),Regensburg Leitlinien-relevante Studie Vorhofflimmern

SPIRonolactone In the Treatment for Heart Failure (SPIRIT-HF-DZHK8)

The SPIRIT-HF-DZHK8 study investigates whether the drug spironolactone can reduce the number of people with preserved ejection fraction who end up in hospital and the number of people who die from heart failure.

Recruiting status
Recruiting ongoing
Principal Investigators
Burkert Pieske, Frank Edelmann (Berlin)
11/2018 1300 EUR 7.014.000,21 Berlin,Elsterwerda,Bernau,Greifswald,Lübeck,Kiel,Bremen,Gießen,Göttingen,Mainz,Bad Nauheim,Mannheim,Heidelberg,München,Halle (Saale) Leitlinien-relevante Studie Herzschwäche

Implantable cardiac monitors in high-risk post-infarction patients with cardiac autonomic dysfunction (SMART-MI-DZHK9)

DZHK researchers from Munich test whether the use of implantable cardiac monitors with home monitoring function is more effective than conventional follow-up for detecting serious arrhythmic events in a newly identified high-risk group of patients.

Recruiting status
Recruiting ongoing
Principal Investigators
Axel Bauer, Stefan Kääb, Steffen Massberg (München)
05/2016 400 EUR 1.876.101,15 München,Kiel,Tübingen,Leipzig,Berlin,Greifswald,Hamburg,Lübeck,Göttingen,Homburg,Karlsruhe,Regensburg,Wuppertal,Dresden,Essen,Münster,Aachen,Mainz,Wiesbaden,Mannheim,Heidelberg,Bernried,Füssen,Nürnberg,Weiden i.d. O Frühe klinische Studie Durchblutungsstörungen des Herzmuskels

Apixaban versus Phenprocoumon: oral anticoagulation plus antiplatelet therapy in patients with acute coronary syndrome and atrial fibrillation (APPROACH-ACS-AF-DZHK7)

DZHK researchers compare two therapies in patients with atrial fibrillation, who have also had a heart attack in order to find out which therapy leads to less bleedings.

Recruiting status
Recruiting ongoing
Principal Investigators
Reza Wakili, Steffen Massberg (München)
07/2016 400 EUR 838.671 München,Coburg,Berlin,Greifswald,Rostock,Göttingen,Mainz,Heidelberg,Kiel,Essen,Aachen,Mannheim,Lüdenscheid Leitlinien-relevante Studie Durchblutungsstörungen des Herzmuskels

Intravenous iron in patients with systolic heart failure and iron deficiency to improve morbidity and mortality (FAIR-HF2-DZHK5)

The FAIR-HF2 study will be assessing whether treatment with intravenously administered ferric carboxymaltose improves the chances of survival and helps to reduce the number of hospitalisations of heart failure patients diagnosed with iron deficiency.

Recruiting status
Recruiting ongoing
Principal Investigators
Mahir Karakas (Hamburg), Stefan Anker (Berlin)
03/2017 1200 EUR 6.578.978,32 Göttingen,Hamburg,Berlin,Lübeck,Kiel,Magdeburg,Mainz,Bad Nauheim,Homburg,Mannheim,Heidelberg,Ulm,Nürnberg,Jena,Greifswald,Rostock,Bremen,Mönchengladbach,Remscheid,München,Mühldorf,Bad Friedrichshall,Dresden,Halle (Saale),Burg Leitlinien-relevante Studie Herzschwäche

Immediate unselected coronary angiography versus delayed triage in survivors of out-of-hospital cardiac arrest without ST-segment elevation (TOMAHAWK-DZHK4)

TOMAHAWK compares the effects of immediate coronary angiography to delayed intervention in survivors of cardiac arrest who occurred outside a hospital and without ST elevation.

Recruiting status
Recruiting complete, follow-up continuing
Principal Investigators
Steffen Desch (Lübeck), Holger Thiele
11/2016 545 EUR 2.815.469,11 Lübeck,Leipzig,Jena,Berlin,Greifswald,Buchholz,Kiel,Flensburg,Schwalmstadt,Göttingen,Mönchengladbach,Herne,Mainz,Frankfurt am Main,Bad Nauheim,Langen,Limburg,Ludwigshafen,Mannheim,Heidelberg,Bad Krozingen,München,Neumarkt,Regensburg,Würzburg,Erfurt,Bad Berka,Essen,Tübingen Leitlinien-relevante Studie Herzstillstand

Early versus emergency left ventricular assist device implantation in patients awaiting cardiac transplantation (VAD-DZHK3)

This study is expected to deliver guideline-relevant findings for the future treatment of patients with terminal heart failure.

Recruiting status
Recruiting ongoing
Principal Investigators
Volkmar Falk, Christoph Knosalla (Berlin), Gerd Hasenfuß, Tim Friede (Göttingen)
07/2015 200 EUR 3.102.028,87 Berlin,Hamburg,Kiel,Bad Nauheim,Heidelberg,München,Leipzig,Jena,Bad Oeynhausen,Hannover,Bad Krozingen,Göttingen,Magdeburg Leitlinien-relevante Studie Herzschwäche

Systolic dysfunction to congestive heart failure cohort study (TransitionCHF-DZHK2)

This cohort study explores ways of predicting when decreased cardiac performance without symptoms will develop into a clinically manifest disease.

Recruiting status
Recruiting ongoing
Principal Investigators
Gerd Hasenfuß, Rolf Wachter, Frank Edelmann (Göttingen)
12/2014 1000 EUR 1.957.843 Göttingen,Berlin,Greifswald,Hamburg,Mainz,Frankfurt am Main,Heidelberg,München,Mannheim,Kiel,Bad Nauheim,Würzburg Kohorte Herzschwäche

Translational registry for cardiomyopathies (TORCH)

Recruiting status
Recruiting complete, follow-up complete
Principal Investigators
Hugo Katus (Heidelberg), Wolfgang Hoffmann (Greifswald)
12/2014 2300 0 Heidelberg,Berlin,Greifswald,Hamburg,Lübeck,Göttingen,Mainz,Frankfurt am Main,Bad Nauheim,Mannheim,München,Hannover,Kiel Register Herzmuskelerkrankungen

Prospective, randomized trial of ticagrelor versus prasugrel in patients with acute coronary syndrome (ISAR-REACT 5)

Recruiting status
Recruiting complete
Principal Investigators
Adnan Kastrati, Stefanie Schüpke (München)
09/2013 4000 0 Leitlinien-relevante Studie

SORT - AF Supervised Obesity Reduction Trial for AF Ablation Patients (SORT-AF)

Recruiting status
Recruiting complete
Principal Investigators
Stephan Willems (Hamburg), Daniel Steven (Köln)
01/2014 140 0 Leitlinien-relevante Studie

Evaluation of the safety and efficacy of the OPTIMIZER ® system in subjects with moderate-to-severe heart failure (FIX-HF-5C)

Recruiting status
Recruiting complete
Principal Investigators
Gerd Hasenfuß (Göttingen)
10/2014 160 0 Leitlinien-relevante Studie

Non-vitamin K antagonist oral anticoagulants in patients with atrial high rate episodes (NOAH-AFNET 6)

Principal Investigators
Paulus Kirchhof (Birmingham, Münster)
06/2016 3400 0 Leitlinien-relevante Studie

National register for congenital heart defects (NRCHD)

Principal Investigators
Ulrike Bauer, Thomas Pickardt (Berlin)
2000 0 0 Register

No entries found for search criteria