Heart–brain interaction

The heart and brain are closely connected. This area of research examines how dysfunction in one organ impacts another, and how this understanding can enhance the prevention, diagnosis, and treatment of diseases.

Why this area matters

For example, a stroke can lead to heart problems, while heart failure can increase the risk of cognitive impairment. Such interactions are common, yet they are still too often overlooked in diagnosis and therapy. For patients, this means an increased risk of secondary conditions and a poorer prognosis.

Our research approach

We study the biological and clinical mechanisms that link the heart and brain. These include changes in blood flow, metabolism, inflammation and neural regulation. By combining imaging, biomarkers, and clinical data, we can better identify risk factors.

Based on this, we develop methods for early diagnosis and test preventive and therapeutic strategies. Our goal is to reduce the risk of secondary diseases and improve care for patients with heart and brain disorders in the long term.

Spokespersons

  • Matthias Endres, Berlin
  • Julian Wagner, RheinMain
  • Constanze Schmidt, Lower Saxony (Lead Spokesperson)

Are you conducting research within or outside the DZHK and would like to connect with this focus area? Please contact:

focusareas@dzhk.de