Tricuspid-Valve Intervention in Heart Failure (N Engl J Med)

DZHK authors: Jörg Hausleiter, Thomas J. Stocker, Philipp Lurz, Niklas Schofer, Christian Frerker, Johanne Frank, Holger Thiele, Erion Xhepa, David M. Leistner, Tobias Kister, Tobias Ruf, Muhammed Gerçek, Derk Frank, Ingo Eitel, Ralph Stephan von Bardeleben, Daniel Kalbacher, Michael Näbauer, Steffen Massberg

The DZHK-funded TRICI-HF-DZHK24 study investigated whether transcatheter tricuspid-valve repair improves outcomes in patients with symptomatic severe tricuspid regurgitation and an increased risk of heart-failure events.
Compared with medical therapy alone, transcatheter repair plus medical therapy improved the combined outcome of survival, heart-failure hospitalization and quality of life at one year. Over three years, it was also associated with a substantially lower risk of death or hospitalization for heart failure.
For patients, this means that transcatheter tricuspid-valve repair may offer a treatment option that not only improves quality of life but can also reduce the risk of hospitalization and death.


Link to publication:
Hausleiter J, Stocker TJ, Geisler T, et al. Tricuspid-Valve Intervention in Heart Failure. N Engl J Med. 2026;395(14):1363-1373. doi:10.1056/NEJMoa2606934

Link to press release:
Minimally Invasive Tricuspid Valve Repair Reduces Mortality and Hospitalisations