Publications 2023

Here you will find publications of the DZHK in chronological order. First authors in grey are members of the Young DZHK. For more publications, please also check out the websites of the individual research institutions that participate in the DZHK.

Zu den DZHK Papers of the Month


Effects of empaglifozin on collagen biomarkers in patients with Heart Failure. Findings from the EMPEROR trials. Ferreira, J. P., Butler, J., Anker, S. D., Januzzi, J. L., Panova-Noeva, M., Reese-Petersen, A. L., Sattar, N., Schueler, E., Pocock, S. J., Filippatos, G., Packer, M., Sumin, M., Zannad, F., committees, E. & investigators. Eur J Heart Fail (2023). 

GPD1L-A306del modifies sodium current in a family carrying the dysfunctional SCN5A-G1661R mutation associated with Brugada syndrome. Semino, F., Darche, F. F., Bruehl, C., Koenen, M., Skladny, H., Katus, H. A., Frey, N., Draguhn, A. & Schweizer, P. A. Pflugers Arch (2023). 

Repeat pulmonary vein isolation and anterior line ablation using a novel point-by-point pulsed field ablation system. Wenzel, J. P., Lemoine, M. D., Rottner, L., My, I., Moser, F., Obergassel, J., Nies, M., Riess, J., Ismaili, D., Nikorowitsch, J., Ouyang, F., Kirchhof, P., Rillig, A., Metzner, A. & Reissmann, B. Heart Rhythm (2023). 

Risk Assessment Of Coronary Obstruction For The ACURATE Transcatheter Heart Valve. Kim, W. K., Eckel, C., Charitos, E. I., Renker, M., Grothusen, C., Choi, Y. H., Hamm, C., Blumenstein, J., Sossalla, S. & Mollmann, H. Am J Cardiol (2023). 

Correction: Completing the view - histologic insights from circular AAA specimen including 3D imaging : A methodologic approach towards histologic analysis of circumferential AAA samples. Menges, A. L., Nackenhorst, M., Muller, J. R., Engl, M. L., Hegenloh, R., Pelisek, J., Geibelt, E., Hofmann, A., Reeps, C., Biro, G., Eckstein, H. H., Zimmermann, A., Magee, D., Falk, M., Sachs, N. & Busch, A. Diagn Pathol 18, 130 (2023). 

Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis. Agarwal, R., Tu, W., Farjat, A. E., Farag, Y. M. K., Toto, R., Kaul, S., Lawatscheck, R., Rohwedder, K., Ruilope, L. M., Rossing, P., Pitt, B., Filippatos, G., Anker, S. D., Bakris, G. L., Fidelio, D. K. D. & Investigators, F.-D. Ann Intern Med (2023). 

Finerenone in Black Patients With Type 2 Diabetes and CKD: A Post hoc Analysis of the Pooled FIDELIO-DKD and FIGARO-DKD Trials. Flack, J. M., Agarwal, R., Anker, S. D., Pitt, B., Ruilope, L. M., Rossing, P., Adler, S. G., Fried, L., Jamerson, K., Toto, R., Brinker, M., Farjat, A. E., Kolkhof, P., Lawatscheck, R., Joseph, A., Bakris, G. L., Fidelio, D. K. D. & Investigators, F.-D. Kidney Med 5, 100730 (2023). 

Goal-directed colloid versus crystalloid therapy and microcirculatory blood flow following ischemia/reperfusion. Behem, C. R., Friedheim, T., Holthusen, H., Rapp, A., Suntrop, T., Graessler, M. F., Pinnschmidt, H. O., Wipper, S. H., von Lucadou, M., Schwedhelm, E., Renne, T., Pfister, K., Schierling, W. & Trepte, C. J. C. Microvasc Res 152, 104630 (2023). 

Response to: Correspondence on 'Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: still needed further discussion' by Wang et al. Hannemann, A., Mayerle, J. & Beyer, G. Gut (2023). 

Dermal features derived from optoacoustic tomograms via machine learning correlate microangiopathy phenotypes with diabetes stage. Karlas, A., Katsouli, N., Fasoula, N. A., Bariotakis, M., Chlis, N. K., Omar, M., He, H., Iakovakis, D., Schaffer, C., Kallmayer, M., Fuchtenbusch, M., Ziegler, A., Eckstein, H. H., Hadjileontiadis, L. & Ntziachristos, V. Nat Biomed Eng 7, 1667-1682 (2023). 

Diagnostic value of papillary muscle hypertrophy and mitral valve thickness to discriminate cardiac amyloidosis and Fabry disease. Mattig, I., Steudel, T., Barzen, G., Frumkin, D., Spethmann, S., Dorta, E. R., Stangl, K., Heidecker, B., Landmesser, U., Knebel, F., Canaan-Kuhl, S., Hahn, K. & Brand, A. Int J Cardiol, 131629 (2023). 

Evaluation of MR-safe bioptomes for MR-guided endomyocardial biopsy in minipigs: a potential radiation-free clinical approach. Svetlove, A., Ritter, C. O., Dullin, C., Schmid, M., Schauer, S., Uihlein, J., Uecker, M., Mietsch, M., Stadelmann, C., Lotz, J. & Unterberg-Buchwald, C. Eur Radiol Exp 7, 76 (2023). 

Lysinuric protein intolerance caused by a homozygous SLC7A7 deletion and presented with hyperferritinemia and osteoporosis in two siblings. Kalay, I., Aykut, H., Caliskan, Z., Yigit, G. & Wollnik, B. Mol Genet Metab Rep 37, 101022 (2023). 

Smoking influence in Takotsubo syndrome: insights from an international cohort. Nunez-Gil, I. J., Santoro, F., Vazirani, R., Novo, G., Blanco-Ponce, E., Arcari, L., Uribarri, A., Cacciotti, L., Guerra, F., Salamanca, J., Musumeci, B., Vedia, O., Mariano, E., Fernandez-Cordon, C., Caldarola, P., Montisci, R., Brunetti, N. D., El-Battrawy, I., Abumayyaleh, M., Akin, I., Eitel, I. & Stiermaier, T. Front Cardiovasc Med 10, 1282018 (2023). 

Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis. Pappritz, K., Puhl, S. L., Matz, I., Brauer, E., Shia, Y. X., El-Shafeey, M., Koch, S. E., Miteva, K., Mucha, C., Duda, G. N., Petersen, A., Steffens, S., Tschope, C. & Van Linthout, S. Front Cardiovasc Med 10, 1117419 (2023). 

Kinin B1 receptor controls maternal adiponectin levels and influences offspring weight gain. Alves-Silva, T., Hungaro, T. G. R., Freitas-Lima, L. C., de Melo Arthur, G., Arruda, A. C., Santos, R. B., Oyama, L. M., Mori, M. A. S., Bader, M. & Araujo, R. C. iScience 26, 108409 (2023). 

Dissolution of spiral wave's core using cardiac optogenetics. Hussaini, S., Ladke, S. L., Schroder-Schetelig, J., Venkatesan, V., Quinonez Uribe, R. A., Richter, C., Majumder, R. & Luther, S. PLoS Comput Biol 19, e1011660 (2023). 

RNA Modification That Breaks the Heart: RNA Acetylase Nat10 Promotes Fibrosis. Kurian, L. & Brandes, R. P. Circ Res 133, 1003-1005 (2023). 

Impaired Detoxification of Trans, Trans-2,4-Decadienal, an Oxidation Product from Omega-6 Fatty Acids, Alters Insulin Signaling, Gluconeogenesis and Promotes Microvascular Disease. Qian, X., Klatt, S., Bennewitz, K., Wohlfart, D. P., Lou, B., Meng, Y., Buettner, M., Poschet, G., Morgenstern, J., Fleming, T., Sticht, C., Hausser, I., Fleming, I., Szendroedi, J., Nawroth, P. P. & Kroll, J. Adv Sci (Weinh), e2302325 (2023). 

Editorial for "Right Ventricular Function in Takayasu's Arteritis Patients With Pulmonary Artery Involvement Using MRI Feature Tracking". Voges, I. & Krupickova, S. J Magn Reson Imaging (2023). 

Safety and Tolerability of Inclisiran for Treatment of Hypercholesterolemia in 7 Clinical Trials. Wright, R. S., Koenig, W., Landmesser, U., Leiter, L. A., Raal, F. J., Schwartz, G. G., Lesogor, A., Maheux, P., Stratz, C., Zang, X. & Ray, K. K. J Am Coll Cardiol 82, 2251-2261 (2023). 

Extract from the 2022 ESC Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery - Patient Blood Management. Halvorsen, S., Mehilli, J., Choorapoikayil, S. & Zacharowski, K. Blood Transfus (2023). 

An ex-vivo and in-vitro dynamic simulator for surgical and transcatheter mitral valve interventions. Karl, R., Romano, G., Marx, J., Eden, M., Schlegel, P., Stroh, L., Fischer, S., Hehl, M., Kuhle, R., Mohl, L., Karck, M., Frey, N., De Simone, R. & Engelhardt, S. Int J Comput Assist Radiol Surg (2023). 

Inflammatory burden, lifestyle and atherosclerotic cardiovascular disease: insights from a population based cohort study. Bay, B., Blaum, C., Kellner, C., Bei der Kellen, R., Ojeda, F., Waibel, J., Arnold, N., Behrendt, C. A., Rimmele, D. L., Thomalla, G., Twerenbold, R., Blankenberg, S., Zyriax, B., Brunner, F. J. & Waldeyer, C. Sci Rep 13, 21761 (2023). 

Role of Phosphodiesterase 1 in the Regulation of Real-Time cGMP Levels and Contractility in Adult Mouse Cardiomyocytes. Bork, N. I., Subramanian, H., Kurelic, R., Nikolaev, V. O. & Rybalkin, S. D. Cells 12 (2023). 

Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. Fernando, R., Shindyapina, A. V., Ost, M., Santesmasses, D., Hu, Y., Tyshkovskiy, A., Yim, S. H., Weiss, J., Gladyshev, V. N., Grune, T. & Castro, J. P. Commun Biol 6, 1240 (2023). 

Optimization of the Reconstruction Settings for Low-Dose Ultra-High-Resolution Photon-Counting Detector CT of the Lungs. Graafen, D., Halfmann, M. C., Emrich, T., Yang, Y., Kreuter, M., Duber, C., Kloeckner, R., Muller, L. & Jorg, T. Diagnostics (Basel) 13 (2023). 

The Potential of Intertwining Gene Diagnostics and Surgery for Mitral Valve Prolapse. Iske, J., Roesel, M. J., Cesarovic, N., Pitts, L., Steiner, A., Knoedler, L., Nazari-Shafti, T. Z., Akansel, S., Jacobs, S., Falk, V., Kempfert, J. & Kofler, M. J Clin Med 12 (2023). 

Systemic inflammatory response syndrome in patients undergoing transcatheter aortic valve implantation. Syryca, F., Pellegrini, C., Rheude, T., Zobel, F., Kornhuber, K., Xhepa, E., Mayr, N. P., Alvarez-Covarrubias, H. A., Holdenrieder, S., Schunkert, H., Thilo, C., Kastrati, A. & Joner, M. Cardiovasc Revasc Med (2023). 

Wnt/beta-Catenin-Signaling Modulates Megakaryopoiesis at the Megakaryocyte-Erythrocyte Progenitor Stage in the Hematopoietic System. Yalcin, B. H., Macas, J., Wiercinska, E., Harter, P. N., Fawaz, M., Schmachtel, T., Ghiro, I., Bieniek, E., Kosanovic, D., Thom, S., Fruttiger, M., Taketo, M. M., Schermuly, R. T., Rieger, M. A., Plate, K. H., Bonig, H. & Liebner, S. Cells 12 (2023). 

Unraveling the brain's response to hypoglycemia: Neurovascular coupling. Duarte, J. M. & Schwaninger, M. J Cereb Blood Flow Metab, 271678X231220082 (2023). 

Role of endothelial PDGFB in arterio-venous malformations pathogenesis. Lin, Y., Gahn, J., Banerjee, K., Dobreva, G., Singhal, M., Dubrac, A. & Ola, R. Angiogenesis (2023). 

Last, but Not Least: TricValve Implantation Reduces Heart Failure Burden in Severe Tricuspid Regurgitation. Stocker, T. J. JACC Cardiovasc Interv (2023). 

Programming human cell fate: overcoming challenges and unlocking potential through technological breakthroughs. Lin, H. C., Makhlouf, A., Vazquez Echegaray, C., Zawada, D. & Simoes, F. Development 150 (2023). 

Prognostic utility of a multi-biomarker panel in patients with suspected myocardial infarction. Toprak, B., Weimann, J., Lehmacher, J., Haller, P. M., Hartikainen, T. S., Schock, A., Karakas, M., Renne, T., Zeller, T., Twerenbold, R., Sorensen, N. A., Westermann, D. & Neumann, J. T. Clin Res Cardiol (2023). 

Microdissection and Immunofluorescence Staining of Myocardial Sleeves in Murine Pulmonary Veins. Villgrater, H. E., Xia, R., Sharma Chivukula, A., Tomsits, P. & Clauss, S. J Vis Exp (2023). 

Longitudinal development of central SBP in children with congenital heart disease. Willinger, L., Brudy, L., Meyer, M., Oberhoffer-Fritz, R., Ewert, P. & Muller, J. J Cardiovasc Med (Hagerstown) 25, 68-75 (2024). 

A nationwide trend analysis on the usage of endomyocardial biopsy. Keller, K., Gobel, S., Gori, T., Munzel, T., Wenzel, P. & Hobohm, L. Clin Cardiol, e24198 (2023). 

miR-222 inhibits pathological cardiac hypertrophyand heart failure. Liu, X., Li, H., Hastings, M. H., Xiao, C., Damilano, F., Platt, C., Lerchenmuller, C., Zhu, H., Wei, X. P., Yeri, A., Most, P. & Rosenzweig, A. Cardiovasc Res (2023). 

Impact of Anemia and Iron Deficiency on Outcomes in Cardiogenic Shock Complicating Acute Myocardial Infarction. Obradovic, D., Loncar, G., Zeymer, U., Poss, J., Feistritzer, H. J., Freund, A., Jobs, A., Fuernau, G., Desch, S., Ceglarek, U., Isermann, B., von Haehling, S., Anker, S. D., Buttner, P. & Thiele, H. Eur J Heart Fail (2023). 

Late-stage synthesis of heterobifunctional molecules for PROTAC applications via ruthenium catalysed C‒H amidation. Antermite, D., Friis, S. D., Johansson, J. R., Putra, O. D., Ackermann, L. & Johansson, M. J. Nat Commun 14, 8222 (2023). 

Hypertension in the first blood pressure reading and the risk of cardiovascular disease mortality in the general population: findings from the prospective KORA study. Atasoy, S., Henningsen, P., Johar, H., Middeke, M., Sattel, H., Linkohr, B., Ruckert-Eheberg, I. M., Heier, M., Peters, A. & Ladwig, K. H. J Hypertens (2023). 

Tricuspid valve disease and cardiac implantable electronic devices. Andreas, M., Burri, H., Praz, F., Soliman, O., Badano, L., Barreiro, M., Cavalcante, J. L., de Potter, T., Doenst, T., Friedrichs, K., Hausleiter, J., Karam, N., Kodali, S., Latib, A., Marijon, E., Mittal, S., Nickenig, G., Rinaldi, A., Rudzinski, P., Russo, M., Starck, C., von Bardeleben, R. S., Wunderlich, N., Zamorano, J. L., Hahn, R. T., Maisano, F. & Leclercq, C. Eur Heart J (2023). 

Surgical ablation of long-standing persistent atrial fibrillation: 1-year outcomes from the CArdioSurgEry Atrial Fibrillation (CASE-AF) registry. Grubitzsch, H., Caliskan, E., Ouarrak, T., Senges, J., Doll, N., Knaut, M., Lewalter, T., Eichinger, W., Niemann, B., Friedrich, I., Hanke, T., Falk, V. & Investigators, C.-A. Interdiscip Cardiovasc Thorac Surg (2023). 

Immunomodulatory leptin receptor(+) sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis. Haberman, E. R., Sarker, G., Arus, B. A., Ziegler, K. A., Meunier, S., Martinez-Sanchez, N., Freibergerova, E., Yilmaz-Ozcan, S., Fernandez-Gonzalez, I., Zentai, C., O'Brien, C. J. O., Grainger, D. E., Sidarta-Oliveira, D., Chakarov, S., Raimondi, A., Iannacone, M., Engelhardt, S., Lopez, M., Ginhoux, F. & Domingos, A. I. Immunity (2023). 

Recognizing patients as candidates for temporary mechanical circulatory support along the spectrum of cardiogenic shock. Montisci, A., Panoulas, V., Chieffo, A., Skurk, C., Schafer, A., Werner, N., Baldetti, L., D'Ettore, N. & Pappalardo, F. Eur Heart J Suppl 25, I3-I10 (2023). 

From escalation to weaning strategies: how to integrate the ECMELLA concept. Schrage, B., Bernhardt, A., Potapov, E., Bertoldi, L. F. & Mangner, N. Eur Heart J Suppl 25, I39-I43 (2023). 

In memoriam: Prof. Dr. rer. nat. Jeanette Erdmann. Shah, P. W., Hashmi, S., Reinberger, T., Odenthal, N., Eichelmann, L., Kosenko, D., Ahmad, I., Al-Hasani, J., Demal, T. J., Aherrahrou, Z. & Aherrahrou, R. IUBMB Life (2023). 

Extent of Abdominal Aortic Calcification Is Associated With Incident Rapid Weight Loss Over 5 Years: The Perth Longitudinal Study of Ageing Women. Smith, C., Sim, M., Dalla Via, J., Gebre, A. K., Zhu, K., Lim, W. H., Teh, R., Kiel, D. P., Schousboe, J. T., Levinger, I., von Haehling, S., Woodman, R., Coats, A. J. S., Prince, R. L. & Lewis, J. R. Arterioscler Thromb Vasc Biol 44, e54-e64 (2024). 

Multi-parametric non-contrast cardiac magnetic resonance for the differentiation between cardiac amyloidosis and hypertrophic cardiomyopathy. Steen, H., Montenbruck, M., Kallifatidis, A., Andre, F., Frey, N., Kelle, S. & Korosoglou, G. Clin Res Cardiol (2023). 

Timing and treatment strategies according to SCAI classification in cardiogenic shock. Tarantini, G., Masiero, G., Thiele, H., Iannaccone, M., Schrage, B., Hassager, C., Woitek, F., Chieffo, A. & Moller, J. E. Eur Heart J Suppl 25, I19-I23 (2023). 

Implications for neutrophils in cardiac arrhythmias. Hegemann, N., Barth, L., Doering, Y., Voigt, N. & Grune, J. Am J Physiol Heart Circ Physiol (2023). 

Ultrasonographic assessment of pulmonary and central venous congestion in experimental heart failure. Hegemann, N., Sang, P., Kim, J. H., Kocana, C., Momin, N., Klages, J., Kucherenko, M. M., Knosalla, C., O'Brien, B., Simmons, S., Nahrendorf, M., Kuebler, W. M. & Grune, J. Am J Physiol Heart Circ Physiol (2023). 

Serum lipoprotein subfractions are associated with the periodontal status: Results from the population-based cohort SHIP-TREND. Kapp, M., Holtfreter, B., Kocher, T., Friedrich, N., Pink, C., Volzke, H. & Nauck, M. J Clin Periodontol (2023). 

Remodelling of cAMP dynamics within the SERCA2a microdomain in heart failure with preserved ejection fraction caused by obesity and type 2 diabetes. Lai, P., Hille, S. S., Subramanian, H., Weigman, R., Roser, P., Muller, O. J., Nikolaev, V. O. & De Jong, K. A. Cardiovasc Res (2023). 

Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype. Maus, M., Lopez-Polo, V., Mateo, L., Lafarga, M., Aguilera, M., De Lama, E., Meyer, K., Sola, A., Lopez-Martinez, C., Lopez-Alonso, I., Guasch-Piqueras, M., Hernandez-Gonzalez, F., Chaib, S., Rovira, M., Sanchez, M., Faner, R., Agusti, A., Dieguez-Hurtado, R., Ortega, S., Manonelles, A., Engelhardt, S., Monteiro, F., Stephan-Otto Attolini, C., Prats, N., Albaiceta, G., Cruzado, J. M. & Serrano, M. Nat Metab (2023). 

Assessment of oropharyngeal respiratory volume and sleep apnoea scores using peripheral arterial tonometry may improve diagnosis and treatment planning of combined dysgnathia therapy approaches. Wiechens, B., Backhaus, S. J., Oestreicher, D., Beutner, D., Schliephake, H., Meyer-Marcotty, P. & Brockmeyer, P. J Oral Rehabil (2023). 

Major In-Hospital Complications after Catheter Ablation of Cardiac Arrhythmias - Individual Case Analysis of 43,031 Procedures. Eckardt, L., Doldi, F., Anwar, O., Gessler, N., Scherschel, K., Kahle, A. K., von Falkenhausen, A. S., Thaler, R., Wolfes, J., Metzner, A., Meyer, C., Willems, S., Kobe, J., Lange, P. S., Frommeyer, G., Kuck, K. H., Kaab, S., Steinbeck, G. & Sinner, M. F. Europace (2023). 

Insertion of a FLAG-tag sequence at the end of exon 9 of the TBX5 gene in three induced pluripotent stem cell lines (DHMi004-A-4, DHMi004-A-5, DHMi004-A-6) by CRISPR/Cas9 technology. Lahm, H., Singh, N. K., Gottmann, I., Doppler, S. A., Dzilic, E., Preisler, H., Schneider, S., Lange, R., Krane, M. & Dressen, M. Stem Cell Res 74, 103261 (2023). 

Safety and efficacy of factor XIa inhibition with milvexian for secondary stroke prevention (AXIOMATIC-SSP): a phase 2, international, randomised, double-blind, placebo-controlled, dose-finding trial. Sharma, M., Molina, C. A., Toyoda, K., Bereczki, D., Bangdiwala, S. I., Kasner, S. E., Lutsep, H. L., Tsivgoulis, G., Ntaios, G., Czlonkowska, A., Shuaib, A., Amarenco, P., Endres, M., Yoon, B. W., Tanne, D., Toni, D., Yperzeele, L., von Weitzel-Mudersbach, P., Sampaio Silva, G., Avezum, A., Dawson, J., Strbian, D., Tatlisumak, T., Eckstein, J., Ameriso, S. F., Weber, J. R., Sandset, E. C., Goar Pogosova, N., Lavados, P. M., Arauz, A., Gailani, D., Diener, H. C., Bernstein, R. A., Cordonnier, C., Kahl, A., Abelian, G., Donovan, M., Pachai, C., Li, D. & Hankey, G. J. Lancet Neurol 23, 46-59 (2024). 

Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention. Araki, M., Park, S. J., Dauerman, H. L., Uemura, S., Kim, J. S., Di Mario, C., Johnson, T. W., Guagliumi, G., Kastrati, A., Joner, M., Holm, N. R., Alfonso, F., Wijns, W., Adriaenssens, T., Nef, H., Rioufol, G., Amabile, N., Souteyrand, G., Meneveau, N., Gerbaud, E., Opolski, M. P., Gonzalo, N., Tearney, G. J., Bouma, B., Aguirre, A. D., Mintz, G. S., Stone, G. W., Bourantas, C. V., Raber, L., Gili, S., Mizuno, K., Kimura, S., Shinke, T., Hong, M. K., Jang, Y., Cho, J. M., Yan, B. P., Porto, I., Niccoli, G., Montone, R. A., Thondapu, V., Papafaklis, M. I., Michalis, L. K., Reynolds, H., Saw, J., Libby, P., Weisz, G., Iannaccone, M., Gori, T., Toutouzas, K., Yonetsu, T., Minami, Y., Takano, M., Raffel, O. C., Kurihara, O., Soeda, T., Sugiyama, T., Kim, H. O., Lee, T., Higuma, T., Nakajima, A., Yamamoto, E., Bryniarski, K. L., Di Vito, L., Vergallo, R., Fracassi, F., Russo, M., Seegers, L. M., McNulty, I., Park, S., Feldman, M., Escaned, J., Prati, F., Arbustini, E., Pinto, F. J., Waksman, R., Garcia-Garcia, H. M., Maehara, A., Ali, Z., Finn, A. V., Virmani, R., Kini, A. S., Daemen, J., Kume, T., Hibi, K., Tanaka, A., Akasaka, T., Kubo, T., Yasuda, S., Croce, K., Granada, J. F., Lerman, A., Prasad, A., Regar, E., Saito, Y., Sankardas, M. A., Subban, V., Weissman, N. J., Chen, Y., Yu, B., Nicholls, S. J., Barlis, P., West, N. E. J., Arbab-Zadeh, A., Ye, J. C., Dijkstra, J., Lee, H., Narula, J., Crea, F., Nakamura, S., Kakuta, T., Fujimoto, J., Fuster, V. & Jang, I. K. Nat Rev Cardiol (2023). 

Age standardization and time-of-day performance for the Oldenburg Sentence Test (OLSA): results from the population-based Gutenberg Health Study. O'Brien, K., Hackenberg, B., Doge, J., Bohnert, A., Rader, T., Lackner, K. J., Beutel, M. E., Munzel, T., Wild, P. S., Chalabi, J., Schuster, A. K., Schmidtmann, I., Matthias, C. & Bahr-Hamm, K. Eur Arch Otorhinolaryngol (2023). 

Increased Chamber Resting Tone Is a Key Determinant of Left Ventricular Diastolic Dysfunction. Tamargo, M., Martinez-Legazpi, P., Espinosa, M. A., Lyon, A., Mendez, I., Gutierrez-Ibanes, E., Fernandez, A. I., Prieto-Arevalo, R., Gonzalez-Mansilla, A., Arts, T., Delhaas, T., Mombiela, T., Sanz-Ruiz, R., Elizaga, J., Yotti, R., Tschope, C., Fernandez-Aviles, F., Lumens, J. & Bermejo, J. Circ Heart Fail 16, e010673 (2023). 

Medical graphics to improve patient understanding and anxiety in elderly and cognitively impaired patients scheduled for transcatheter aortic valve implantation (TAVI). Brand, A., Hornig, C., Crayen, C., Hamann, A., Martineck, S., Leistner, D. M., Dreger, H., Sundermann, S., Unbehaun, A., Sherif, M., Haghikia, A., Bischoff, S., Lueg, J., Kuhnle, Y., Paul, O., Squier, S., Stangl, K., Falk, V., Landmesser, U. & Stangl, V. Clin Res Cardiol (2023). 

Regulation of Thyroid Hormone Gatekeepers by Thyrotropin in Tanycytes. Chandrasekar, A., Schmidtlein, P. M., Neve, V., Rivagorda, M., Spiecker, F., Gauthier, K., Prevot, V., Schwaninger, M. & Muller-Fielitz, H. Thyroid (2024). 

Interdental cleaning aids are beneficial for oral health at 7-year follow-up: Results from the Study of Health in Pomerania (SHIP-TREND). Holtfreter, B., Conrad, E., Kocher, T., Baumeister, S. E., Volzke, H. & Welk, A. J Clin Periodontol (2023). 

Noninvasive evaluation of pulmonary artery stiffness in heart failure patients via cardiovascular magnetic resonance. Hou, X., Hashemi, D., Erley, J., Neye, M., Bucius, P., Tanacli, R., Kuhne, T., Kelm, M., Motzkus, L., Blum, M., Edelmann, F., Kuebler, W. M., Pieske, B., Dungen, H. D., Schuster, A., Stoiber, L. & Kelle, S. Sci Rep 13, 22656 (2023). 

Insulin resistance in Takotsubo syndrome. Bruns, B., Joos, M., Elsous, N., Katus, H. A., Schultz, J. H., Frey, N., Backs, J. & Meder, B. ESC Heart Fail (2023). A simple tool for evaluation of inflammation in psoriasis: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as markers in psoriasis patients and related murine models of psoriasis-like skin disease. Kommoss, K. S., Bieler, T., Ringen, J., Lehmann, A., Mihalceanu, S., Hobohm, L., Keller, K., Brand, A., Fischer, B., Kramer, D., Wild, J., Waisman, A., Enk, A., Schakel, K., Heikenwalder, M. & Karbach, S. J Mol Med (Berl) (2023). 

Automated image quality assessment for selecting among multiple magnetic resonance image acquisitions in the German National Cohort study. Schuppert, C., Rospleszcz, S., Hirsch, J. G., Hoinkiss, D. C., Kohn, A., von Kruchten, R., Russe, M. F., Keil, T., Krist, L., Schmidt, B., Michels, K. B., Schipf, S., Brenner, H., Kroncke, T. J., Pischon, T., Niendorf, T., Schulz-Menger, J., Forsting, M., Volzke, H., Hosten, N., Bulow, R., Zaitsev, M., Kauczor, H. U., Bamberg, F., Gunther, M. & Schlett, C. L. Sci Rep 13, 22745 (2023). 

Growth differentiation factor-15 in sodium-glucose cotransporter 2 inhibition: Mechanistic insights from the EMPEROR program. Seoudy, H., Voran, J. C. & Frank, D. Eur J Heart Fail (2023). 

Prognostic Value of Gut Microbe-Generated Metabolite Phenylacetylglutamine in Patients with Heart Failure. Tang, W. H. W., Nemet, I., Li, X. S., Wu, Y., Haghikia, A., Witkowski, M., Koeth, R. A., Demuth, I., Konig, M., Steinhagen-Thiessen, E., Backhed, F., Fischbach, M. A., Deb, A., Landmesser, U. & Hazen, S. L. Eur J Heart Fail (2023). 

Long-term exposure to ambient air pollution and inflammatory response in the KORA study. Vogli, M., Peters, A., Wolf, K., Thorand, B., Herder, C., Koenig, W., Cyrys, J., Maestri, E., Marmiroli, N., Karrasch, S., Zhang, S. & Pickford, R. Sci Total Environ 912, 169416 (2024). 

Epidemiology, Pathophysiology, Diagnosis and Management of Chronic Right-Sided Heart Failure and Tricuspid Regurgitation. A clinical consensus statement of the Heart Failure Association (HFA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. Adamo, M., Chioncel, O., Pagnesi, M., Bayes-Genis, A., Abdelhamid, M., Anker, S. D., Antohi, E. L., Badano, L., Ben Gal, T., Bohm, M., Delgado, V., Dreyfus, J., Faletra, F. F., Farmakis, D., Filippatos, G., Grapsa, J., Gustafsson, F., Hausleiter, J., Jaarsma, T., Karam, N., Lund, L., Lurz, P., Maisano, F., Moura, B., Mullens, W., Praz, F., Sannino, A., Savarese, G., Tocchetti, C. G., van Empel, V. P. M., von Bardeleben, R. S., Yilmaz, M. B., Zamorano, J. L., Ponikowski, P., Barbato, E., Rosano, G. M. C. & Metra, M. Eur J Heart Fail (2023). 

A Systematic Review of Lipid-Focused Cardiovascular Disease Research: Trends and Opportunities. Anyaegbunam, U. A., More, P., Fontaine, J. F., Cate, V. T., Bauer, K., Distler, U., Araldi, E., Bindila, L., Wild, P. & Andrade-Navarro, M. A. Curr Issues Mol Biol 45, 9904-9916 (2023). 

GPER activation attenuates cardiac dysfunction by upregulating the SIRT1/3-AMPK-UCP2 pathway in postmenopausal diabetic rats. Azizian, H., Farhadi, Z., Bader, M., Alizadeh Ghalenoei, J., Ghafari, M. A. & Mahmoodzadeh, S. PLoS One 18, e0293630 (2023). 

Vertigo and its burden of disease-Results from a population-based cohort study. Hackenberg, B., O'Brien, K., Doge, J., Lackner, K. J., Beutel, M. E., Munzel, T., Wild, P. S., Pfeiffer, N., Chalabi, J., Matthias, C. & Bahr-Hamm, K. Laryngoscope Investig Otolaryngol 8, 1624-1630 (2023). 

Beyond the Basics: Unraveling the Complexity of Coronary Artery Calcification. Hashmi, S., Shah, P. W., Aherrahrou, Z., Aikawa, E. & Aherrahrou, R. Cells 12 (2023). 

Long-term use of everolimus for refractory arrhythmia in a child with tuberous sclerosis complex. Hofmann, C., Syrbe, S., Hebe, J., Kreft, J., Stark, S., Milde, T., Volkers, M., Hoffmann, G. F., Gorenflo, M. & Kovacevic, A. Am J Med Genet A (2023). 

In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector. Laurette, P., Cao, C., Ramanujam, D., Schwaderer, M., Lueneburg, T., Kuss, S., Weiss, L., Dilshat, R., Furlong, E. E. M., Rezende, F., Engelhardt, S. & Gilsbach, R. Circ Res (2023). 

Adipose retinol saturase is regulated by beta-adrenergic signaling and its deletion impairs lipolysis in adipocytes and acute cold tolerance in mice. Li, C., Kiefer, M. F., Dittrich, S., Flores, R. E., Meng, Y., Yang, N., Wulff, S., Gohlke, S., Sommerfeld, M., Wowro, S. J., Petricek, K. M., Durbeck, D., Spranger, L., Mai, K., Scholz, H., Schulz, T. J. & Schupp, M. Mol Metab 79, 101855 (2024). 

Statin therapy and outcome in Takotsubo syndrome patients: Results from the multicenter international GEIST registry. Novo, G., Arcari, L., Stiermaier, T., Alaimo, C., El-Battrawy, I., Cacciotti, L., Guerra, F., Musumeci, B., Mariano, E., Parisi, G., Montisci, R., Vazirani, R., Perez Castellanos, A., Uribarri, A., Corbi-Pascual, M., Salamanca, J., Akin, I., Thiele, H., Brunetti, N. D., Eitel, I., Nunez Gil, I. J. & Santoro, F. Atherosclerosis 389, 117421 (2024). 

Risk Stratification of QTc Prolongation in Critically Ill Patients Receiving Antipsychotics for the Management of Delirium Symptoms. Sadlonova, M., Beach, S. R., Funk, M. C., Rosen, J. H., Ramirez Gamero, A. F., Karlson, R. A., Huffman, J. C. & Celano, C. M. J Intensive Care Med, 8850666231222470 (2023). 

Protocol to develop force-generating human skeletal muscle organoids. Shahriyari, M., Rinn, M., Hofemeier, A. D., Babych, A., Zimmermann, W. H. & Tiburcy, M. STAR Protoc 5, 102794 (2023). 

Mid-term results following pulmonary artery patch augmentation in congenital heart disease. von Stumm, M., Hildebrandt, T., Schaeffer, T., Heinisch, P. P., Georgiev, S., Wolf, C., Ewert, P., Horer, J. & Cleuziou, J. Transl Pediatr 12, 1992-2000 (2023). 

Concomitant percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation. Fischer, J., Steffen, J., Arlart, T., Haum, M., Gschwendtner, S., Doldi, P. M., Rizas, K., Theiss, H., Braun, D., Orban, M., Peterss, S., Hausleiter, J., Massberg, S. & Deseive, S. Catheter Cardiovasc Interv 103, 186-193 (2024). 

Producing and Testing Prototype Tissue-Engineered 3D Tri-Leaflet Valved Stents on Biodegradable Poly-epsilon-Caprolactone Scaffolds. Lutter, G., Pommert, N. S., Zhang, X., Seiler, J., Saeid Nia, M., Meier, D., Sellers, S. L., Gorb, S. N., Hansen, J. H., Seoudy, H., Muller, O. J., Saad, M., Haneya, A., Frank, D., Puehler, T. & Sathananthan, J. Int J Mol Sci 24 (2023). 

Bioanalysis of the Ex Vivo Labile PACE4 Inhibitory Peptide Ac-[d-Leu]LLLRVK-Amba in Whole Blood Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry Quantification. Sauter, M., Haag, J., Bay, C., Leuschner, F., Haefeli, W. E., Kuhn, T. C. & Burhenne, J. Pharmaceutics 15 (2023). 

Value of Post-/Pre-Procedural Aortic Regurgitation Ratio vs. Pre-Procedural Aortic Valve Calcium Score to Predict Moderate to Severe Paravalvular Leak Requiring Post-Dilation after Transcatheter Aortic Valve Implantation. Uebelacker, R., Martin, S. S., Vasa-Nicotera, M. & Mas-Peiro, S. J Clin Med 12 (2023). 

Differential biomarker expression in heart failure patients with and without mitral regurgitation: Insights from BIOSTAT-CHF. Adamo, M., Pagnesi, M., Di Pasquale, M., Ravera, A., Dickstein, K., Ng, L. L., Anker, S. D., Cleland, J. G., Filippatos, G. S., Lang, C. C., Ponikowski, P., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Lipsic, E., Voors, A. & Metra, M. Int J Cardiol, 131664 (2023). 

Generation of an RBM20-mutation-associated left-ventricular non-compaction cardiomyopathy iPSC line (UMGi255-A) into a DCM genetic background to investigate monogenetic cardiomyopathies. Eberl, H., Rebs, S., Hoppe, S., Sedaghat-Hamedani, F., Kayvanpour, E., Meder, B. & Streckfuss-Bomeke, K. Stem Cell Res 74, 103290 (2024). 

Cholesterol crystals at the culprit lesion in patients with acute coronary syndrome are associated with worse cardiovascular outcomes at two years follow up - results from the translational OPTICO-ACS study program (R2). Nelles, G., Abdelwahed, Y. S., Seppelt, C., Meteva, D., Stahli, B. E., Rai, H., Seegers, L. M., Sieronski, L., Musfeldt, J., Gerhardt, T., Riedel, M., Skurk, C., Haghikia, A., Sinning, D., Dreger, H., Knebel, F., Trippel, T. D., Krisper, M., Klotsche, J., Joner, M., Landmesser, U. & Leistner, D. M. Int J Cardiol, 131665 (2023). 

Health position paper and redox perspectives - Disease burden by transportation noise. Sorensen, M., Pershagen, G., Thacher, J. D., Lanki, T., Wicki, B., Roosli, M., Vienneau, D., Cantuaria, M. L., Schmidt, J. H., Aasvang, G. M., Al-Kindi, S., Osborne, M. T., Wenzel, P., Sastre, J., Fleming, I., Schulz, R., Hahad, O., Kuntic, M., Zielonka, J., Sies, H., Grune, T., Frenis, K., Munzel, T. & Daiber, A. Redox Biol 69, 102995 (2024). 

Metabolic dysfunction associated steatotic liver disease and the heart. Driessen, S., Francque, S. M., Anker, S. D., Castro Cabezas, M., Grobbee, D. E., Tushuizen, M. E. & Holleboom, A. G. Hepatology (2023). 

Artificial intelligence-based analysis of body composition predicts outcome in patients receiving long-term mechanical circulatory support. Just, I. A., Schoenrath, F., Roehrich, L., Heil, E., Stein, J., Auer, T. A., Fehrenbach, U., Potapov, E., Solowjowa, N., Balzer, F., Geisel, D., Braun, J. & Boening, G. J Cachexia Sarcopenia Muscle (2023). 

Human epithelial lung cell toxicity assessment of collected graphite particles from an iron casting industry (in vitro study). Zendehdel, R., Hahad, O. & Panjali, Z. Int J Environ Health Res, 1-10 (2023). 

In-hospital Outcomes of Rotational Atherectomy in ST-elevation Myocardial Infarction - Results from the Multicenter ROTA-STEMI Network. Hemetsberger, R., Mankerious, N., Muntane-Carol, G., Temporal, J., Sulimov, D., Gaede, L., Woitek, F., Fadeuilhe Grau, E., Scalamogna, M., Olschewski, M., Mitsis, A., Ruzsa, Z., Toth, G. G., Heyer, H., Toelg, R., Gomez-Hospital, J. A., Mugge, A., Hengstenberg, C., Mangner, N., Gori, T., Cassese, S., Carrillo Suarez, X., Abdel-Wahab, M., Johnson, T., Richardt, G. & Allali, A. Can J Cardiol (2023). 

Noncoding RNAs in the Vasculature: Basic Mechanisms and Therapeutic Perspectives. Maegdefessel, L., Boon, R. A. & Dimmeler, S. Arterioscler Thromb Vasc Biol 44, 3-6 (2024). 

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: Update 2023. von Haehling, S., Coats, A. J. S. & Anker, S. D. J Cachexia Sarcopenia Muscle 14, 2981-2983 (2023). 

Secondary retensioning of a tether-based device for transapical transcatheter mitral valve implantation. Beyer, M., Muller, D., De Marco, F., Badhwar, V., Obadia, J. F., Praz, F., Modine, T., Tonino, P., Dahle, G., Cerillo, A., Ludwig, S. & Conradi, L. Eur J Cardiothorac Surg (2023). 

Metabolic Communication by SGLT2 Inhibition. Billing, A. M., Kim, Y. C., Gullaksen, S., Schrage, B., Raabe, J., Hutzfeldt, A., Demir, F., Kovalenko, E., Lasse, M., Dugourd, A., Fallegger, R., Klampe, B., Jaegers, J., Li, Q., Kravtsova, O., Crespo-Masip, M., Palermo, A., Fenton, R. A., Hoxha, E., Blankenberg, S., Kirchhof, P., Huber, T. B., Laugesen, E., Zeller, T., Chrysopolou, M., Saez-Rodriguez, J., Magnussen, C., Eschenhagen, T., Staruschenko, A., Siuzdak, G., Poulsen, P. L., Schwab, C., Cuello, F., Vallon, V. & Rinschen, M. M. Circulation (2023). 

Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis. Prapiadou, S., Zivkovic, L., Thorand, B., George, M. J., van der Laan, S. W., Malik, R., Herder, C., Koenig, W., Ueland, T., Kleveland, O., Aukrust, P., Gullestad, L., Bernhagen, J., Pasterkamp, G., Peters, A., Hingorani, A. D., Rosand, J., Dichgans, M., Anderson, C. D. & Georgakis, M. K. Circulation (2023). 

An unexpected cellular fountain of youth: platelets provide factors rejuvenating brain functions. Langer, H. F. Signal Transduct Target Ther 8, 461 (2023).


Paper of the Month

High-Sensitivity Cardiac Troponin I Enhances Preeclampsia Prediction Beyond Maternal Factors and the sFlt-1/PlGF Ratio. DZHK-authors: Stefan Blankenberg, Tanja Zeller. Circulation, 2023.

Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice. Cimen, I., Natarelli, L., Abedi Kichi, Z., Henderson, J. M., Farina, F. M., Briem, E., Aslani, M., Megens, R. T. A., Jansen, Y., Mann-Fallenbuchel, E., Gencer, S., Duchene, J., Nazari-Jahantigh, M., van der Vorst, E. P. C., Enard, W., Doring, Y., Schober, A., Santovito, D. & Weber, C. Sci Transl Med 15, eadf3357 (2023). 

Editorial: Women in Cardiac Electrophysiology: 2022. Meo, M., Fenske, S. & Chowdhury, R. Front Physiol 14, 1299403 (2023). 

Clinical Outcomes by Sex After Pulsed Field Ablation of Atrial Fibrillation. Turagam, M. K., Neuzil, P., Schmidt, B., Reichlin, T., Neven, K., Metzner, A., Hansen, J., Blaauw, Y., Maury, P., Arentz, T., Sommer, P., Anic, A., Anselme, F., Boveda, S., Deneke, T., Willems, S., van der Voort, P., Tilz, R., Funasako, M., Scherr, D., Wakili, R., Steven, D., Kautzner, J., Vijgen, J., Jais, P., Petru, J., Chun, J., Roten, L., Futing, A., Lemoine, M. D., Ruwald, M., Mulder, B. A., Rollin, A., Lehrmann, H., Fink, T., Jurisic, Z., Chaumont, C., Adelino, R., Nentwich, K., Gunawardene, M., Ouss, A., Heeger, C. H., Manninger, M., Bohnen, J. E., Sultan, A., Peichl, P., Koopman, P., Derval, N., Kueffer, T. & Reddy, V. Y. JAMA Cardiol (2023). 

Protocol of the Berlin Long-term Observation of Vascular Events (BeLOVE): a prospective cohort study with deep phenotyping and long-term follow up of cardiovascular high-risk patients. Weber, J. E., Ahmadi, M., Boldt, L. H., Eckardt, K. U., Edelmann, F., Gerhardt, H., Grittner, U., Haubold, K., Hubner, N., Kollmus-Heege, J., Landmesser, U., Leistner, D. M., Mai, K., Muller, D. N., Nolte, C. H., Pieske, B., Piper, S. K., Rattan, S., Rauch, G., Schmidt, S., Schmidt-Ott, K. M., Schonrath, K., Schulz-Menger, J., Schweizerhof, O., Siegerink, B., Spranger, J., Ramachandran, V. S., Witzenrath, M., Endres, M. & Pischon, T. BMJ Open 13, e076415 (2023). 

Polygenic Risk Score Associates With Atherosclerotic Plaque Characteristics at Autopsy. Cornelissen, A., Gadhoke, N. V., Ryan, K., Hodonsky, C. J., Mitchell, R., Bihlmeyer, N., Duong, T., Chen, Z., Dikongue, A., Sakamoto, A., Sato, Y., Kawakami, R., Mori, M., Kawai, K., Fernandez, R., Ghosh, S. K. B., Braumann, R., Abebe, B., Kutys, R., Kutyna, M., Romero, M. E., Kolodgie, F. D., Miller, C. L., Hong, C. C., Grove, M. L., Brody, J. A., Sotoodehnia, N., Arking, D. E., Schunkert, H., Mitchell, B. D., Guo, L., Virmani, R. & Finn, A. V. Arterioscler Thromb Vasc Biol (2023). 

Copeptin, Natriuretic Peptides, and Cardiovascular Outcomes in Patients With CKD: The German Chronic Kidney Disease (GCKD) Study. Schneider, M. P., Schmid, M., Nadal, J., Krane, V., Saritas, T., Busch, M., Schultheiss, U. T., Meiselbach, H., Friedrich, N., Nauck, M., Floege, J., Kronenberg, F., Wanner, C., Eckardt, K. U. & investigators, G. s. Kidney Med 5, 100725 (2023). 

Cardiac Troponin Assays to Distinguish Between Acute and Chronic Myocardial Injury. Sorensen, N. A., Guo, L., Haller, P. M., Dehkordi, F., Lehmacher, J., Schock, A., Toprak, B., Zeller, T., Twerenbold, R. & Neumann, J. T. J Am Coll Cardiol 82, 1885-1887 (2023). 

Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retina. Wang, Y., Halawa, M., Chatterjee, A., Eshwaran, R., Qiu, Y., Wibowo, Y. C., Pan, J., Wieland, T. & Feng, Y. Mol Med 29, 152 (2023). 

Ethanol deprivation and central 5-HT deficiency differentially affect the mRNA editing of the 5-HT(2C) receptor in the mouse brain. Zaniewska, M., Alenina, N., Frohler, S., Chen, W. & Bader, M. Pharmacol Rep 75, 1502-1521 (2023). 

Laser light in the era of pulsed field ablation - still a competitor? Heeger, C. H. & Tilz, R. R. J Interv Card Electrophysiol (2023). 

Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome. Kutschka, I., Bertero, E., Wasmus, C., Xiao, K., Yang, L., Chen, X., Oshima, Y., Fischer, M., Erk, M., Arslan, B., Alhasan, L., Grosser, D., Ermer, K. J., Nickel, A., Kohlhaas, M., Eberl, H., Rebs, S., Streckfuss-Bomeke, K., Schmitz, W., Rehling, P., Thum, T., Higuchi, T., Rabinowitz, J., Maack, C. & Dudek, J. Basic Res Cardiol 118, 47 (2023). 

Prognostic impact of pre-frailty and frailty in women undergoing TAVR: Insights from the WIN-TAVI Registry. Petrovic, M., Spirito, A., Sartori, S., Vogel, B., Tchetche, D., Petronio, A. S., Mehilli, J., Lefevre, T., Presbitero, P., Capranzano, P., Pileggi, B., Iadanza, A., Sardella, G., Van Mieghem, N. M., Meliga, E., Feng, Y., Dumonteil, N., Cohen, R., Fraccaro, C., Trabattoni, D., Mikhail, G., Ferrer-Gracia, M. C., Naber, C., Sharma, S. K., Watanabe, Y., Morice, M. C., Dangas, G. D., Chieffo, A. & Mehran, R. Can J Cardiol (2023). 

Disturbance in bodily experience following ventricular assist device implantation. Richter, F., Spielmann, H., Semmig-Koenze, S., Spitz-Koberich, C., Knosalla, C., Kugler, C., Tigges-Limmer, K. & Albert, W. J Heart Lung Transplant (2023). 

Modified balloons to prepare severely calcified coronary lesions before stent implantation: a systematic review and meta-analysis of randomized trials. Scalamogna, M., Kuna, C., Voll, F., Aytekin, A., Lahu, S., Kessler, T., Kufner, S., Rheude, T., Sager, H. B., Xhepa, E., Wiebe, J., Joner, M., Ndrepepa, G., Kastrati, A. & Cassese, S. Clin Res Cardiol (2023). 

Impact of temporal and spatial resolution on atrial feature tracking cardiovascular magnetic resonance imaging. Schmidt-Rimpler, J., Backhaus, S. J., Hartmann, F. P., Schaten, P., Lange, T., Evertz, R., Schulz, A., Kowallick, J. T., Lapinskas, T., Hasenfuss, G., Kelle, S. & Schuster, A. Int J Cardiol, 131563 (2023). 

A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM. Schulz, C., Sonmez, M., Krause, J., Schwedhelm, E., Bangfen, P., Alihodzic, D., Hansen, A., Eschenhagen, T. & Christ, T. Stem Cell Reports 18, 2096-2107 (2023). 

Concurrent hypoglossal and phrenic nerve stimulation in patients with obstructive and treatment emergent central sleep apnea. Steffen, A., Schobel, C., Vogler, J., Bruchhage, K. L. & Tilz, R. R. Sleep Breath (2023). 

[Genetic basis of atrial fibrillation-on the road to precision medicine]. Kany, S. & Schnabel, R. B. Herzschrittmacherther Elektrophysiol (2023). 

Protease-Activated Receptor-1 IgG Autoantibodies in Patients with COVID-19. Reinshagen, L., Nageswaran, V., Heidecke, H., Schulze-Forster, K., Wilde, A. B., Ramezani Rad, P., Poller, W., Asmus, E., Simmons, S., Kuebler, W. M., Witzenrath, M., Marko, L., Jakobs, K., Puccini, M., Leistner, D. M., Rauch-Krohnert, U., Krankel, N., Forslund, S. K., Landmesser, U., Muller, D. N. & Haghikia, A. Thromb Haemost (2023). 

Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs. Shi, R., Reichardt, M., Fiegle, D. J., Kupfer, L. K., Czajka, T., Sun, Z., Salditt, T., Dendorfer, A., Seidel, T. & Bruegmann, T. Cardiovasc Res 119, 2469-2481 (2023). 

Heart rate turbulence in acute ischemic stroke. Stengl, H., Ganeshan, R., von Rennenberg, R., Hellwig, S., Herm, J., Krause, T., Bauer, A., Endres, M., Georg Haeusler, K., Scheitz, J. F. & Nolte, C. H. Eur Stroke J, 23969873231211166 (2023). 

Temporal Changes in Coronary Plaque as Assessed by an Artificial Intelligence Based Optical Coherence Tomography: From the First-in-Human Trial on DREAMS 3G Scaffold. Garcia-Garcia, H. M., Waksman, R., Melaku, G. D., Garg, M., Beyene, S., Wlodarczak, A., Kerai, A., Levine, M. B., van der Schaaf, R. J., Torzewski, J., Ferdinande, B., Escaned, J., Iglesias, J. F., Bennett, J., Toth, G. G., Joner, M., Toelg, R., Wiemer, M., Olivecrona, G., Vermeersch, P. & Haude, M. Eur Heart J Cardiovasc Imaging (2023). 

MePMe-seq: antibody-free simultaneous m(6)A and m(5)C mapping in mRNA by metabolic propargyl labeling and sequencing. Hartstock, K., Kueck, N. A., Spacek, P., Ovcharenko, A., Huwel, S., Cornelissen, N. V., Bollu, A., Dieterich, C. & Rentmeister, A. Nat Commun 14, 7154 (2023). 

Age- and sex-adjusted reference intervals for steroid hormones measured by liquid chromatography-tandem mass spectrometry using a widely available kit. Kunz, S., Wang, X., Ferrari, U., Drey, M., Theodoropoulou, M., Schilbach, K., Reincke, M., Heier, M., Peters, A., Koenig, W., Zeller, T., Thorand, B. & Bidlingmaier, M. Endocr Connect 13 (2024). 

Speos: an ensemble graph representation learning framework to predict core gene candidates for complex diseases. Ratajczak, F., Joblin, M., Hildebrandt, M., Ringsquandl, M., Falter-Braun, P. & Heinig, M. Nat Commun 14, 7206 (2023). 

Cardiac decompensation of patients before transcatheter aortic valve implantation-clinical presentation, responsiveness to associated medication, and prognosis. Fischer-Rasokat, U., Renker, M., Charitos, E. I., Strunk, C., Treiber, J., Rolf, A., Weferling, M., Choi, Y. H., Hamm, C. W. & Kim, W. K. Front Cardiovasc Med 10, 1232054 (2023). 

Impact of pulsed field ablation on intraluminal esophageal temperature. Kirstein, B., Heeger, C. H., Vogler, J., Eitel, C., Feher, M., Phan, H. L., Mushfiq, I., Traub, A., Hatahet, S., Samara, O., Subin, B., Kuck, K. H. & Tilz, R. R. J Cardiovasc Electrophysiol (2023). 

Autoantibodies against the chemokine receptor 3 predict cardiovascular risk. Muller, F. S., Aherrahrou, Z., Grasshoff, H., Heidorn, M. W., Humrich, J. Y., Johanson, L., Aherrahrou, R., Reinberger, T., Schulz, A., Ten Cate, V., Robles, A. P., Koeck, T., Rapp, S., Lange, T., Brachaczek, L., Luebber, F., Erdmann, J., Heidecke, H., Schulze-Forster, K., Dechend, R., Lackner, K. J., Pfeiffer, N., Ghaemi Kerahrodi, J., Tuscher, O., Schwarting, A., Strauch, K., Munzel, T., Prochaska, J. H., Riemekasten, G. & Wild, P. S. Eur Heart J (2023). 

Multiomics Analysis Provides Novel Pathways Related to Progression of Heart Failure. Ouwerkerk, W., Belo Pereira, J. P., Maasland, T., Emmens, J. E., Figarska, S. M., Tromp, J., Koekemoer, A. L., Nelson, C. P., Nath, M., Romaine, S. P. R., Cleland, J. G. F., Zannad, F., van Veldhuisen, D. J., Lang, C. C., Ponikowski, P., Filippatos, G., Anker, S., Metra, M., Dickstein, K., Ng, L. L., de Boer, R. A., van Riel, N., Nieuwdorp, M., Groen, A. K., Stroes, E., Zwinderman, A. H., Samani, N. J., Lam, C. S. P., Levin, E. & Voors, A. A. J Am Coll Cardiol 82, 1921-1931 (2023). 

Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial. Santos-Ferreira, D., Diaz, S. O., Ferreira, J. P., Girerd, N., Pellicori, P., Mariottoni, B., Cosmi, F., Hazebroek, M., Verdonschot, J. A. J., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelmann, F., Clark, A. L., Rossignol, P., Fontes-Carvalho, R., Cleland, J. G. F. & Zannad, F. ESC Heart Fail (2023). 

Endomyocardial biopsy in fulminant myocarditis: need for early and accurate diagnosis to improve the outcome. Schultheiss, H. P. & Escher, F. Eur Heart J (2023). 

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Self-rated physical health predicts mortality in aging persons beyond objective health risks. Reinwarth, A. C., Wicke, F. S., Hettich, N., Ernst, M., Otten, D., Brahler, E., Wild, P. S., Munzel, T., Konig, J., Lackner, K. J., Pfeiffer, N. & Beutel, M. E. Sci Rep 13, 19531 (2023). 

Cystatin C based estimation of chronic kidney disease and amyotrophic lateral sclerosis in the ALS registry Swabia: associated risk and prognostic value. Nagel, G., Kurz, D., Peter, R. S., Rosenbohm, A., Koenig, W., Dupuis, L., Bazner, H., Bortlein, A., Dempewolf, S., Schabet, M., Hecht, M., Kohler, A., Opherk, C., Naegele, A., Sommer, N., Lindner, A., Tumani, H., Ludolph, A. C. & Rothenbacher, D. Sci Rep 13, 19594 (2023). 

Severe aortic regurgitation after short-term treatment with microaxial left ventricular assist device in the transaxillary approach. Wert, L., Falk, V. & Potapov, E. V. Eur Heart J (2023). 

Clearing the air, saving lives: understanding air pollution's impact on out-of-hospital cardiac arrest. Hahad, O., Daiber, A. & Munzel, T. Eur Heart J Acute Cardiovasc Care 12, 818-820 (2023). 

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Low-dose aspirin and incident atrial fibrillation in healthy older individuals: a post-hoc analysis of the ASPREE Trial. Ball, J., Neumann, J. T., Tonkin, A. M., Kirchhof, P., Freedman, B., Brodtmann, A., Reid, C., Nelson, M. R., Beilin, L. J., Fitzgerald, S., Stub, D., Woods, R. L. & McNeil, J. J. Eur Heart J Cardiovasc Pharmacother (2023). 

Pituitary gland volumes and stress: Results of a population-based adult sample. Klinger-Konig, J., Ittermann, T., Martin, II, Marx, S., Schroeder, H. W. S., Nauck, M., Volzke, H., Bulow, R. & Grabe, H. J. J Psychiatr Res 168, 325-333 (2023). 

Cardiomyocyte-specific disruption of the circadian BMAL1-REV-ERBalpha/beta regulatory network impacts distinct miRNA species in the murine heart. Latimer, M. N., Williams, L. J., Shanmugan, G., Carpenter, B. J., Lazar, M. A., Dierickx, P. & Young, M. E. Commun Biol 6, 1149 (2023). 

Anticoagulation with edoxaban in patients with long Atrial High-Rate Episodes >/=24 hours. Becher, N., Toennis, T., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Cabanelas, N., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G. A., Dichtl, W., Diener, H. C., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A. N. L., Lip, G. Y. H., Lubinski, A., Marijon, E., Merkely, B., Mont, L., Ozga, A. K., Rajappan, K., Sarkozy, A., Scherr, D., Schnabel, R. B., Schotten, U., Sehner, S., Simantirakis, E., Vardas, P., Velchev, V., Wichterle, D., Zapf, A. & Kirchhof, P. Eur Heart J (2023). 

External mechanical loading overrules cell-cell mechanical communication in sprouting angiogenesis during early bone regeneration. Dazzi, C., Mehl, J., Benamar, M., Gerhardt, H., Knaus, P., Duda, G. N. & Checa, S. PLoS Comput Biol 19, e1011647 (2023). 

Chemokines, molecular drivers of thromboinflammation and immunothrombosis. Leberzammer, J. & von Hundelshausen, P. Front Immunol 14, 1276353 (2023). 

Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study. Pink, C., Holtfreter, B., Volzke, H., Nauck, M., Dorr, M. & Kocher, T. BMC Med 21, 430 (2023). 

Do in-person and computer-based brief alcohol interventions reduce tobacco smoking among general hospital patients? Secondary outcomes from a randomized controlled trial. Filipa, K. W., Sophie, B., Anika, T., Gallus, B., Ulrich, J., Beate, G. & Jennis, F. A. Addict Sci Clin Pract 18, 68 (2023). 

Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomere. Kellermayer, D., Tordai, H., Kiss, B., Torok, G., Peter, D. M., Sayour, A. A., Polos, M., Hartyanszky, I., Szilveszter, B., Labeit, S., Gango, A., Bedics, G., Bodor, C., Radovits, T., Merkely, B. & Kellermayer, M. S. J Clin Invest 134 (2024). 

Heart Rate Reduction and Outcomes in Heart Failure Outpatients. Memenga, F., Rybczynski, M., Magnussen, C., Gossling, A., Kondziella, C., Becher, N., Becher, P. M., Bernadyn, J., Berisha, F., Bremer, W., Sinning, C., Blankenberg, S., Kirchhof, P. & Knappe, D. J Clin Med 12 (2023). 

Coronary no-reflow and adverse events in patients with acute myocardial infarction after percutaneous coronary intervention with current drug-eluting stents and third-generation P2Y(12) inhibitors. Ndrepepa, G., Cassese, S., Xhepa, E., Joner, M., Sager, H. B., Kufner, S., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Clin Res Cardiol (2023). 

Clinical course and follow-up of pediatric patients with COVID-19 vaccine-associated myocarditis compared to non-vaccine-associated myocarditis within the prospective multicenter registry-"MYKKE". Rolfs, N., Huber, C., Schwarzkopf, E., Mentzer, D., Keller-Stanislawski, B., Opgen-Rhein, B., Frede, W., Rentzsch, A., Hecht, T., Boehne, M., Grafmann, M., Kiski, D., Graumann, I., Foth, R., Voges, I., Schweigmann, U., Ruf, B., Fischer, M., Wiegand, G., Klingel, K., Pickardt, T., Friede, T., Messroghli, D., Schubert, S., Seidel, F. & Consortium, M. Am Heart J 267, 101-115 (2024). 

Detection and modification of biomarkers of inflammation determining successful rhythm control in patients with atrial fibrillation. Schreiber, T., Grune, J., Landmesser, U. & Attanasio, P. Biomarkers, 1-24 (2023). 

Why you should pay more attention to your cells' sex. Stangl, V. & Lorenz, M. J Physiol 601, 5581-5584 (2023). 

Long-term outcomes from upgrade to cardiac resynchronisation therapy in ischaemic versus non-ischaemic heart disease. Yuecel, G., Stoesslein, K., Gaasch, L., Kodeih, A., Oeztuerk, O. N., Hetjens, S., Yazdani, B., Pfleger, S., Liebe, V., Rudic, B., Behnes, M., Langer, H., Duerschmied, D., Akin, I. & Kuschyk, J. Acta Cardiol, 1-11 (2023). 

Growth differentiation factor-15 and the effect of empagliflozin in heart failure: Findings from the EMPEROR program. Ferreira, J. P., Packer, M., Butler, J., Filippatos, G., Pocock, S. J., Januzzi, J. L., Sattar, N., Maldonado, S. G., Panova-Noeva, M., Sumin, M., Masson, S., Anker, S. D. & Zannad, F. Eur J Heart Fail (2023). 

Multimodal characterization of dilated cardiomyopathy: Geno- And Phenotyping of PrImary Cardiomyopathy (GrAPHIC). Keil, L., Berisha, F., Ritter, S., Skibowski, J., Subramanian, H., Nikolaev, V. O., Kubisch, C., Woitschach, R., Fabritz, L., Twerenbold, R., Blankenberg, S., Weidemann, S., Zeller, T., Kirchhof, P., Reichart, D. & Magnussen, C. ESC Heart Fail (2023). 

The cardiovascular effects of novel weight loss therapies. Usman, M. S., Davies, M., Hall, M. E., Verma, S., Anker, S. D., Rosenstock, J. & Butler, J. Eur Heart J (2023). 

Single-cell, whole-embryo phenotyping of mammalian developmental disorders. Huang, X., Henck, J., Qiu, C., Sreenivasan, V. K. A., Balachandran, S., Amarie, O. V., Hrabe de Angelis, M., Behncke, R. Y., Chan, W. L., Despang, A., Dickel, D. E., Duran, M., Feuchtinger, A., Fuchs, H., Gailus-Durner, V., Haag, N., Hagerling, R., Hansmeier, N., Hennig, F., Marshall, C., Rajderkar, S., Ringel, A., Robson, M., Saunders, L. M., da Silva-Buttkus, P., Spielmann, N., Srivatsan, S. R., Ulferts, S., Wittler, L., Zhu, Y., Kalscheuer, V. M., Ibrahim, D. M., Kurth, I., Kornak, U., Visel, A., Pennacchio, L. A., Beier, D. R., Trapnell, C., Cao, J., Shendure, J. & Spielmann, M. Nature 623, 772-781 (2023). 

miR-223-3p Prevents Necroptotic Macrophage Death by Targeting Ripk3 in a Negative Feedback Loop and Consequently Ameliorates Advanced Atherosclerosis. Jia, Y., Cheng, L., Yang, J., Mao, J., Xie, Y., Yang, X., Zhang, X., Wang, D., Zhao, Z., Schober, A. & Wei, Y. Arterioscler Thromb Vasc Biol (2023). 

The 8th International RASopathies Symposium: Expanding research and care practice through global collaboration and advocacy. Pierpont, E. I., Bennett, A. M., Schoyer, L., Stronach, B., Anschutz, A., Borrie, S. C., Briggs, B., Burkitt-Wright, E., Castel, P., Cirstea, I. C., Draaisma, F., Ellis, M., Fear, V. S., Frone, M. N., Flex, E., Gelb, B. D., Green, T., Gripp, K. W., Khoshkhoo, S., Kieran, M. W., Kleemann, K., Klein-Tasman, B. P., Kontaridis, M. I., Kruszka, P., Leoni, C., Liu, C. Z., Merchant, N., Magoulas, P. L., Moertel, C., Prada, C. E., Rauen, K. A., Roelofs, R., Rossignol, R., Sevilla, C., Sevilla, G., Sheedy, R., Stieglitz, E., Sun, D., Tiemens, D., White, F., Wingbermuhle, E., Wolf, C., Zenker, M. & Andelfinger, G. Am J Med Genet A (2023). 

Multimorbidity in patients with acute heart failure across world regions and country income levels (REPORT-HF): a prospective, multicentre, global cohort study. Gerhardt, T., Gerhardt, L. M. S., Ouwerkerk, W., Roth, G. A., Dickstein, K., Collins, S. P., Cleland, J. G. F., Dahlstrom, U., Tay, W. T., Ertl, G., Hassanein, M., Perrone, S. V., Ghadanfar, M., Schweizer, A., Obergfell, A., Filippatos, G., Lam, C. S. P., Tromp, J. & Angermann, C. E. Lancet Glob Health 11, e1874-e1884 (2023). 

Dataset of single nucleotide polymorphisms of immune-associated genes in patients with SARS-CoV-2 infection. Katsaouni, N., Llavona, P., Khodamoradi, Y., Otto, A. K., Korber, S., Geisen, C., Seidl, C., Vehreschild, M., Ciesek, S., Ackermann, J., Koch, I., Schulz, M. H. & Krause, D. S. PLoS One 18, e0287725 (2023). 

Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: An analysis of 49 cohorts from 11 European countries. Reinikainen, J., Kuulasmaa, K., Oskarsson, V., Amouyel, P., Biasch, K., Brenner, H., De Ponti, R., Donfrancesco, C., Drygas, W., Ferrieres, J., Grassi, G., Grimsgaard, S., Iacoviello, L., Jousilahti, P., Karhus, L. L., Kee, F., Linneberg, A., Luksiene, D., Marino, J., Moitry, M., Palmieri, L., Peters, A., Piwonska, A., Quarti-Trevano, F., Salomaa, V., Sans, S., Schmidt, C. O., Schottker, B., Soderberg, S., Tamosiunas, A., Thorand, B., Tunstall-Pedoe, H., Vanuzzo, D., Veronesi, G., Woodward, M., Lekadir, K. & Niiranen, T. Eur J Prev Cardiol (2023). 

Small-Molecule Probes as Pharmacological Tools for the Bone Morphogenetic Protein Signaling Pathway. Riege, D., Herschel, S., Fenkl, T. & Schade, D. ACS Pharmacol Transl Sci 6, 1574-1599 (2023). 

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Generalized anxiety is a predictor of impaired quality of life in patients with atrial fibrillation: Findings from the prospective observational ARENA study. Sadlonova, M., Salzmann, S., Senges, J., Celano, C. M., Huffman, J. C., Borggrefe, M., Akin, I., Thomas, D., Schwarzbach, C. J., Kleemann, T., Schneider, S., Hochadel, M., Suselbeck, T., Schwacke, H., Alonso, A., Haass, M., Ladwig, K. H. & Herrmann-Lingen, C. J Psychosom Res 176, 111542 (2024). 

Deletion of vascular thromboxane A(2) receptors and its impact on angiotensin II-induced hypertension and atherosclerotic lesion formation in the aorta of Ldlr-deficient mice. Braun, H., Hauke, M., Petermann, M., Eckenstaler, R., Ripperger, A., Schwedhelm, E., Ludwig-Kraus, B., Bernhard Kraus, F., Jalal Ahmed Shawon, M., Dubourg, V., Zernecke, A., Schreier, B., Gekle, M. & Benndorf, R. A. Biochem Pharmacol, 115916 (2023). 

Supporting and implementing the beneficial parts of the exposome: The environment can be the problem, but it can also be the solution. Hahad, O., Al-Kindi, S., Lelieveld, J., Munzel, T. & Daiber, A. Int J Hyg Environ Health 255, 114290 (2024). 

High-Sensitivity Cardiac Troponin I Enhances Preeclampsia Prediction Beyond Maternal Factors and the sFlt-1/PlGF Ratio. Bacmeister, L., Gossling, A., Buellesbach, A., Birukov, A., Myers, J. E., Thomas, S. T., Lee, S., Andersen, M. S., Jorgensen, J. S., Diemert, A., Blois, S. M., Arck, P. C., Hecher, K., Herse, F., Blankenberg, S., Dechend, R., Westermann, D. & Zeller, T. Circulation (2023). 

Association of systemic inflammation with shock severity, 30-day mortality, and therapy response in patients with cardiogenic shock. Dettling, A., Weimann, J., Sundermeyer, J., Beer, B. N., Besch, L., Becher, P. M., Brunner, F. J., Kluge, S., Kirchhof, P., Blankenberg, S., Westermann, D. & Schrage, B. Clin Res Cardiol (2023). 

Feature-Tracking Strain Parameters Differ Between Highly Accelerated and Conventional Acquisitions: A Multisoftware Assessment. Halfmann, M. C., Klimzak, T., Schoepf, U. J., Kloeckner, R., Chitiboi, T., Schmidt, M., Wenzel, P., Muller, L., Geyer, M., Varga-Szemes, A., Kreitner, K. F., Dueber, C. & Emrich, T. J Thorac Imaging (2023). 

Long-term outcome of patients presenting with myocardial injury or myocardial infarction. Haller, P. M., Kellner, C., Sorensen, N. A., Lehmacher, J., Toprak, B., Schock, A., Hartikainen, T. S., Twerenbold, R., Zeller, T., Westermann, D. & Neumann, J. T. Clin Res Cardiol (2023). 

Deep learning-based NT-proBNP prediction from the ECG for risk assessment in the community. Neyazi, M., Bremer, J. P., Knorr, M. S., Gross, S., Brederecke, J., Schweingruber, N., Csengeri, D., Schrage, B., Bahls, M., Friedrich, N., Zeller, T., Felix, S., Blankenberg, S., Dorr, M., Vollmer, M. & Schnabel, R. B. Clin Chem Lab Med (2023). 

Beyond association: high neutrophil counts are a causal risk factor for atherosclerotic cardiovascular disease. Soehnlein, O. & Doring, Y. Eur Heart J (2023). 

Association between left ventricular ejection fraction, mortality and use of mechanical circulatory support in patients with non-ischaemic cardiogenic shock. Sundermeyer, J., Kellner, C., Beer, B. N., Besch, L., Dettling, A., Bertoldi, L. F., Blankenberg, S., Dauw, J., Dindane, Z., Eckner, D., Eitel, I., Graf, T., Horn, P., Jozwiak-Nozdrzykowska, J., Kirchhof, P., Kluge, S., Linke, A., Landmesser, U., Luedike, P., Lusebrink, E., Majunke, N., Mangner, N., Maniuc, O., Winkler, S. M., Nordbeck, P., Orban, M., Pappalardo, F., Pauschinger, M., Pazdernik, M., Proudfoot, A., Kelham, M., Rassaf, T., Scherer, C., Schulze, P. C., Schwinger, R. H. G., Skurk, C., Sramko, M., Tavazzi, G., Thiele, H., Villanova, L., Morici, N., Westenfeld, R., Winzer, E. B., Westermann, D. & Schrage, B. Clin Res Cardiol (2023). 

Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance. von Scheidt, W., Reichart, B., Meiser, B., von Scheidt, M., Sen, P., Schwarz, F., Harmel, E., Bengel, F. M., Dick, A., Ueberfuhr, P., Reichenspurner, H., Jaeckel, E., Schwinzer, R. & Hagl, C. Clin Res Cardiol (2023). 

Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium. Winters, J., Isaacs, A., Zeemering, S., Kawczynski, M., Maesen, B., Maessen, J., Bidar, E., Boukens, B., Hermans, B., van Hunnik, A., Casadei, B., Fabritz, L., Chua, W., Sommerfeld, L., Guasch, E., Mont, L., Batlle, M., Hatem, S., Kirchhof, P., Wakili, R., Sinner, M., Stoll, M., Goette, A., Verheule, S. & Schotten, U. J Am Heart Assoc, e031220 (2023). 

Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations. Aherrahrou, R., Baig, F., Theofilatos, K., Lue, D., Beele, A., Ord, T., Kaikkonen, M. U., Aherrahrou, Z., Cheng, Q., Ghosh, S., Karnewar, S., Karnewar, V., Finn, A., Owens, G. K., Joner, M., Mayr, M. & Civelek, M. medRxiv (2023). 

Jeanette Erdmann (1965-2023). Aherrahrou, R., Eschenhagen, T., Konig, I. R., Samani, N. J., Schunkert, H. & Aherrahrou, Z. Nat Genet (2023). 

Environmental and climate cardiology: some environmental issues highlighted at the annual meetings of the German Society for Cardiology (DGK) from 2007 to 2023. Hahad, O. Herz (2023). 

Follicular reconstruction and neo-oogenesis in xenotransplantation of human ovarian isolated cells derived from chemotherapy-induced POF patients. Khaleghi, S., Eivazkhani, F., Tavana, S., Moini, A., Novin, M. G., Stoyan, P., Nazarian, H. & Fathi, R. J Biol Eng 17, 70 (2023). 

Generation of an NCS1 gene knockout human induced pluripotent stem cell line using CRISPR/Cas9. Maierhof, S. K., Schinke, C., Cernoch, J., Hew, L., Bruske, L. P., Fernandez Vallone, V., Fischer, K., Stachelscheid, H., Huehnchen, P., Endres, M., Diecke, S., Telugu, N. S. & Boehmerle, W. Stem Cell Res 73, 103253 (2023). 

Association of central blood pressure with an exaggerated blood pressure response to exercise among elite athletes. Most, A., Kraushaar, L., Dorr, O., Keranov, S., Hoelscher, S., Weber, R., Akdogan, E., Groesser, V., Husain-Syed, F., Nef, H., Hamm, C. W. & Bauer, P. Eur J Appl Physiol (2023). 

Applying the TRILUMINATE Eligibility Criteria to Real-World Patients Receiving Tricuspid Valve Transcatheter Edge-to-Edge Repair. Stolz, L., Doldi, P. M., Kresoja, K. P., Bombace, S., Koell, B., Kassar, M., Kirchner, J., Weckbach, L. T., Ludwig, S., Stocker, T. J., Glaser, H., Schober, A. R., Massberg, S., Nabauer, M., Rudolph, V., Kalbacher, D., Praz, F., Lurz, P. & Hausleiter, J. JACC Cardiovasc Interv (2023). 

Cardiovascular and Renal Benefit of Novel Non-steroidal Mineralocorticoid Antagonists in Patients with Diabetes. Kintscher, U. Curr Cardiol Rep (2023). 

The Changing Landscape of Aortic-Valve Stenosis Management. Landmesser, U. N Engl J Med 389, 2008-2009 (2023). 

Rationale and Design of the ESC Heart Failure III Registry - Implementation and Discovery. Lund, L. H., Crespo-Leiro, M. G., Laroche, C., Garcia-Pinilla, J. M., Bennis, A., Vataman, E. B., Polovina, M., Radovanovic, S., Apostolovic, S. R., Asanin, M., Gackowski, A., Kaplon-Cieslicka, A., Cabac-Pogorevici, I., Anker, S. D., Chioncel, O., Coats, A. J. S., Filippatos, G., Lainscak, M., McDonagh, T., Mebazaa, A., Metra, M., Piepoli, M., Rosano, G. M., Ruschitzka, F., Savarese, G., Seferovic, P. M., Iung, B., Popescu, B. A., Maggioni, A. P., Leaders, E. E. H. I. N. & Investigators. Eur J Heart Fail (2023). 

1,4-Benzothiazepines with Cyclopropanol Groups and Their Structural Analogues Exhibit Both RyR2-Stabilizing and SERCA2a-Stimulating Activities. Mitronova, G. Y., Quentin, C., Belov, V. N., Wegener, J. W., Kiszka, K. A. & Lehnart, S. E. J Med Chem 66, 15761-15775 (2023). 

A distinct topology of BTN3A IgV and B30.2 domains controlled by juxtamembrane regions favors optimal human gammadelta T cell phosphoantigen sensing. Karunakaran, M. M., Subramanian, H., Jin, Y., Mohammed, F., Kimmel, B., Juraske, C., Starick, L., Nohren, A., Lander, N., Willcox, C. R., Singh, R., Schamel, W. W., Nikolaev, V. O., Kunzmann, V., Wiemer, A. J., Willcox, B. E. & Herrmann, T. Nat Commun 14, 7617 (2023). 

Drinking patterns of alcohol and risk of major adverse cardiovascular events after an acute coronary syndrome. Tessitore, E., Branca, M., Heg, D., Nanchen, D., Auer, R., Raber, L., Klingenberg, R., Windecker, S., Luscher, T. F., Carballo, S., Matter, C. M., Gmel, G., Mukamal, K. J., Rodondi, N., Carballo, D., Mach, F. & Gencer, B. Eur J Prev Cardiol (2023). 

AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery. Theuerkauf, S. A., Herrera-Carrillo, E., John, F., Zinser, L. J., Molina, M. A., Riechert, V., Thalheimer, F. B., Borner, K., Grimm, D., Chlanda, P., Berkhout, B. & Buchholz, C. J. Biomaterials 303, 122399 (2023). 

Comparing the effectiveness of glucose-lowering agents: real-world data to emulate a four-arm target trial. Ahmed, A., Anker, S. D., Butler, J., Bakris, G. L., Bhatt, D. L., Fonarow, G. C. & Packer, M. Lancet Diabetes Endocrinol 11, 892-894 (2023). 

"Artificial Intelligence-Enabled Assessment of Right Ventricular to Pulmonary Artery Coupling in Patients Undergoing Transcatheter Tricuspid Valve Intervention". Fortmeier, V., Lachmann, M., Stolz, L., von Stein, J., Unterhuber, M., Kassar, M., Gercek, M., Schober, A. R., Stocker, T. J., Omran, H., Korber, M. I., Hesse, A., Harmsen, G., Friedrichs, K. P., Yuasa, S., Rudolph, T. K., Joner, M., Pfister, R., Baldus, S., Laugwitz, K. L., Windecker, S., Praz, F., Lurz, P., Hausleiter, J. & Rudolph, V. Eur Heart J Cardiovasc Imaging (2023). 

Exploration of the Noncoding Genome for Human-Specific Therapeutic Targets-Recent Insights at Molecular and Cellular Level. Poller, W., Sahoo, S., Hajjar, R., Landmesser, U. & Krichevsky, A. M. Cells 12 (2023). 

Periodic repolarization dynamics: Different methods for quantifying low-frequency oscillations of repolarization. Sams, L. E., Worndl, M., Bachinger, L., Villegas Sierra, L. E., Mourouzis, K., Naumann, D., Freyer, L. & Rizas, K. D. J Electrocardiol 82, 11-18 (2023). 

Agreement between high-sensitivity cardiac troponin assays and non-invasive testing, clinical-, quality of care outcomes based on the 2020 ESC guidelines. Karady, J., Mayrhofer, T., Januzzi, J. L., Jr., Udelson, J. E., Fleg, J. L., Merkely, B., Lu, M. T., Peacock, W. F., Nagurney, J. T., Koenig, W., Ferencik, M. & Hoffmann, U. Eur Heart J Acute Cardiovasc Care (2023). 

On- vs. Off-Pump CABG in Heart Failure Patients with Reduced Ejection Fraction (HFrEF): A Multicenter Analysis. Rustenbach, C. J., Reichert, S., Radwan, M., Doll, I., Mustafi, M., Nemeth, A., Marinos, S. L., Berger, R., Baumbach, H., Zdanyte, M., Haeberle, H., Caldonazo, T., Saqer, I., Saha, S., Schnackenburg, P., Djordjevic, I., Krasivskyi, I., Wendt, S., Kuhn, E., Higuita, L. M. S., Doenst, T., Hagl, C., Wahlers, T., Boburg, R. S. & Schlensak, C. Biomedicines 11 (2023). 

Association of body mass index with 30-day all-cause mortality in cardiogenic shock. Schmitt, A., Schupp, T., Rusnak, J., Weidner, K., Ruka, M., Egner-Walter, S., Mashayekhi, K., Tajti, P., Ayoub, M., Behnes, M. & Akin, I. Nutr Metab Cardiovasc Dis (2023). 

Transcriptional Targeting Approaches in Cardiac Gene Transfer Using AAV Vectors. Schroder, L. C., Frank, D. & Muller, O. J. Pathogens 12 (2023). 

Prolonged Door-to-Balloon Time Leads to Endothelial Glycocalyx Damage and Endothelial Dysfunction in Patients with ST-Elevation Myocardial Infarction. Vahldieck, C., Fels, B., Loning, S., Nickel, L., Weil, J. & Kusche-Vihrog, K. Biomedicines 11 (2023). 

Association of Asymmetric and Symmetric Dimethylarginine with Inflammation in the Population-Based Study of Health in Pomerania. Winkler, M. S., Bahls, M., Boger, R. H., Ittermann, T., Dorr, M., Friedrich, N. & Schwedhelm, E. Biomolecules 13 (2023). 

A simple coronary CT angiography-based jeopardy score for the identification of extensive coronary artery disease: Validation against invasive coronary angiography. Schaab, J. A., Candreva, A., Rossi, A., Markendorf, S., Sager, D., Messerli, M., Pazhenkottil, A. P., Benz, D. C., Kaufmann, P. A., Buechel, R. R., Stahli, B. E. & Giannopoulos, A. A. Diagn Interv Imaging (2023). 

Body mass, neuro-hormonal stress processing, and disease activity in lean to obese people with multiple sclerosis. Meyer-Arndt, L., Brasanac, J., Gamradt, S., Bellmann-Strobl, J., Maurer, L., Mai, K., Steward, T., Spranger, J., Schmitz-Hubsch, T., Paul, F., Gold, S. M. & Weygandt, M. J Neurol (2023). 

Pulsed-field versus cryoballoon ablation for atrial fibrillation-Impact of energy source on sedation and analgesia requirement. Wahedi, R., Willems, S., Feldhege, J., Jularic, M., Hartmann, J., Anwar, O., Dickow, J., Harloff, T., Gessler, N. & Gunawardene, M. A. J Cardiovasc Electrophysiol (2023). 

Lipid Lowering Drugs in Acute Coronary Syndromes (ACS). Arnold, N. & Koenig, W. Curr Atheroscler Rep (2023). 

Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome. Chan, J. C., Alenina, N., Cunningham, A. M., Ramakrishnan, A., Shen, L., Bader, M. & Maze, I. bioRxiv (2023). 

Vasoregulatory Autoantibodies and Clinical Outcome After Ischemic Stroke-PROSCIS-B. Liman, T. G., Siegerink, B., Piper, S., Catar, R., Moll, G., Riemekasten, G., Heidecke, H., Heuschmann, P. U., Elkind, M. S. V., Dragun, D. & Endres, M. J Am Heart Assoc 12, e032441 (2023). 

Cardiological parameters predict mortality and cardiotoxicity in oncological patients. Romann, S. W., Finke, D., Heckmann, M. B., Hund, H., Giannitsis, E., Katus, H. A., Frey, N. & Lehmann, L. H. ESC Heart Fail (2023). 

Effects of Mobile Stroke Unit dispatch on blood pressure management and outcomes in patients with intracerebral haematoma: Results from the Berlin_Prehospital Or Usual Care Delivery in acute Stroke (B_PROUD) controlled intervention study. Schwabauer, E., Piccininni, M., Freitag, E., Ebinger, M., Geisler, F., Harmel, P., Hille, A., Lorenz-Meyer, I., Rohrpasser-Napierkowski, I., Kurth, T., Rohmann, J. L., Endres, M., Schlunk, F., Weber, J., Wendt, M. & Audebert, H. J. Eur Stroke J, 23969873231213156 (2023). 

Brain-derived Tau for Monitoring Brain Injury in Acute Ischemic Stroke. Vlegels, N., Gonzalez-Ortiz, F., Knuth, N. L., Khalifeh, N., Gesierich, B., Muller, F., Muller, P., Klein, M., Dimitriadis, K., Franzmeier, N., Liebig, T., Duering, M., Reidler, P., Dichgans, M., Karikari, T. K., Blennow, K. & Tiedt, S. medRxiv (2023). 

Successful treatment of cardiogenic shock due to Takotsubo syndrome with implantation of a temporary microaxial left ventricular assist device in transaxillary approach. von Mackensen, J. K. R., Shazly, A. E., Schoenrath, F., Kempfert, J., Starck, C. T., Potapov, E. V., Jacobs, S., Falk, V. & Wert, L. J Cardiothorac Surg 18, 343 (2023). 

A dual-targeted drug inhibits cardiac ryanodine receptor Ca(2+) leak but activates SERCA2a Ca(2+) uptake. Wegener, J. W., Mitronova, G. Y., ElShareif, L., Quentin, C., Belov, V., Pochechueva, T., Hasenfuss, G., Ackermann, L. & Lehnart, S. E. Life Sci Alliance 7 (2024). 

Atrial fibrosis heterogeneity is a risk for atrial fibrillation in pigs with ischaemic heart failure. Zhang, Z., Vlcek, J., Pauly, V., Hesse, N., Bauer, J., Chataut, K. R., Maderspacher, F., Volz, L. S., Buchberger, K., Xia, R., Hildebrand, B., Kaab, S., Schuttler, D., Tomsits, P. & Clauss, S. Eur J Clin Invest, e14137 (2023). 

Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci. de Las Fuentes, L., Schwander, K. L., Brown, M. R., Bentley, A. R., Winkler, T. W., Sung, Y. J., Munroe, P. B., Miller, C. L., Aschard, H., Aslibekyan, S., Bartz, T. M., Bielak, L. F., Chai, J. F., Cheng, C. Y., Dorajoo, R., Feitosa, M. F., Guo, X., Hartwig, F. P., Horimoto, A., Kolcic, I., Lim, E., Liu, Y., Manning, A. K., Marten, J., Musani, S. K., Noordam, R., Padmanabhan, S., Rankinen, T., Richard, M. A., Ridker, P. M., Smith, A. V., Vojinovic, D., Zonderman, A. B., Alver, M., Boissel, M., Christensen, K., Freedman, B. I., Gao, C., Giulianini, F., Harris, S. E., He, M., Hsu, F. C., Kuhnel, B., Laguzzi, F., Li, X., Lyytikainen, L. P., Nolte, I. M., Poveda, A., Rauramaa, R., Riaz, M., Robino, A., Sofer, T., Takeuchi, F., Tayo, B. O., van der Most, P. J., Verweij, N., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhan, Y., Amin, N., Arking, D. E., Ballantyne, C., Boerwinkle, E., Brody, J. A., Broeckel, U., Campbell, A., Canouil, M., Chai, X., Chen, Y. I., Chen, X., Chitrala, K. N., Concas, M. P., de Faire, U., de Mutsert, R., de Silva, H. J., de Vries, P. S., Do, A., Faul, J. D., Fisher, V., Floyd, J. S., Forrester, T., Friedlander, Y., Girotto, G., Gu, C. C., Hallmans, G., Heikkinen, S., Heng, C. K., Homuth, G., Hunt, S., Ikram, M. A., Jacobs, D. R., Jr., Kavousi, M., Khor, C. C., Kilpelainen, T. O., Koh, W. P., Komulainen, P., Langefeld, C. D., Liang, J., Liu, K., Liu, J., Lohman, K., Magi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Milaneschi, Y., Nauck, M., Nelson, C. P., O'Connell, J. R., Palmer, N. D., Pereira, A. C., Perls, T., Peters, A., Polasek, O., Raitakari, O. T., Rice, K., Rice, T. K., Rich, S. S., Sabanayagam, C., Schreiner, P. J., Shu, X. O., Sidney, S., Sims, M., Smith, J. A., Starr, J. M., Strauch, K., Tai, E. S., Taylor, K. D., Tsai, M. Y., Uitterlinden, A. G., van Heemst, D., Waldenberger, M., Wang, Y. X., Wei, W. B., Wilson, G., Xuan, D., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Becker, D. M., Bonnefond, A., Bowden, D. W., Cooper, R. S., Deary, I. J., Divers, J., Esko, T., Franks, P. W., Froguel, P., Gieger, C., Jonas, J. B., Kato, N., Lakka, T. A., Leander, K., Lehtimaki, T., Magnusson, P. K. E., North, K. E., Ntalla, I., Penninx, B., Samani, N. J., Snieder, H., Spedicati, B., van der Harst, P., Volzke, H., Wagenknecht, L. E., Weir, D. R., Wojczynski, M. K., Wu, T., Zheng, W., Zhu, X., Bouchard, C., Chasman, D. I., Evans, M. K., Fox, E. R., Gudnason, V., Hayward, C., Horta, B. L., Kardia, S. L. R., Krieger, J. E., Mook-Kanamori, D. O., Peyser, P. A., Province, M. M., Psaty, B. M., Rudan, I., Sim, X., Smith, B. H., van Dam, R. M., van Duijn, C. M., Wong, T. Y., Arnett, D. K., Rao, D. C., Gauderman, J., Liu, C. T., Morrison, A. C., Rotter, J. I. & Fornage, M. Front Genet 14, 1235337 (2023). 

Sterility testing of germ-free mouse colonies. Dremova, O., Mimmler, M., Paeslack, N., Khuu, M. P., Gao, Z., Bosmann, M., Garo, L. P., Schon, N., Mechler, A., Beneich, Y., Rebling, V., Mann, A., Pontarollo, G., Kiouptsi, K. & Reinhardt, C. Front Immunol 14, 1275109 (2023). 

Needs of multimorbid heart failure patients and their carers: a qualitative interview study and the creation of personas as a basis for a blended collaborative care intervention. Engelmann, P., Eilerskov, N., Thilsing, T., Bernardini, F., Rasmussen, S., Lowe, B., Herrmann-Lingen, C., Gostoli, S., Andreasson, F., Rafanelli, C., Pedersen, S. S., Jaarsma, T. & Kohlmann, S. Front Cardiovasc Med 10, 1186390 (2023). 

Prevalence and Prognostic Role of Lymphedema in Patients with Deep Venous Thrombosis and Thrombophlebitis. Grigorean, A., Lindenblatt, N., Luchsinger, I., Hobohm, L., Konstantinides, S. V., Munzel, T., Barco, S. & Keller, K. Lymphat Res Biol (2023). 

Optoacoustic biomarkers of lipids, hemorrhage and inflammation in carotid atherosclerosis. Karlas, A., Fasoula, N. A., Kallmayer, M., Schaffer, C., Angelis, G., Katsouli, N., Reidl, M., Duelmer, F., Al Adem, K., Hadjileontiadis, L., Eckstein, H. H. & Ntziachristos, V. Front Cardiovasc Med 10, 1210032 (2023). 

Impact of the COVID-19 pandemic on implementation of novel guideline-directed medical therapies for heart failure in Germany: a nationwide retrospective analysis. Kerwagen, F., Riemer, U., Wachter, R., von Haehling, S., Abdin, A., Bohm, M., Schulz, M. & Stork, S. Lancet Reg Health Eur 35, 100778 (2023). 

Inclisiran in patients with prior myocardial infarction: A post hoc pooled analysis of the ORION-10 and ORION-11 Phase 3 randomised trials. Landmesser, U., Koenig, W., Leiter, L. A., Raal, F. J., Ray, K. K., Wright, R. S., Han, J., Conde, L. G. & Schwartz, G. G. Atherosclerosis 386, 117354 (2023). 

Simultaneous assessment of mechanical and electrical function in Langendorff-perfused ex-vivo mouse hearts. Louradour, J., Ottersberg, R., Segiser, A., Olejnik, A., Martinez-Salazar, B., Siegrist, M., Egle, M., Barbieri, M., Nimani, S., Alerni, N., Doring, Y., Odening, K. E. & Longnus, S. Front Cardiovasc Med 10, 1293032 (2023). 

Recurrent ventricular tachycardia originating from the "left ventricular summit" effectively eliminated by stereotactic irradiation - A case report. Mages, C., Steinfurt, J., Rahm, A. K., Thomas, D., Majidi, R., Kehrle, F., Andre, F., Seidensaal, K., Rhein, B., Wengenmayer, T., Gressler, A., Westermann, D., Herzog, R., Debus, J., Frey, N. & Lugenbiel, P. HeartRhythm Case Rep 9, 802-807 (2023). 

The influence of marathon running on resting-state EEG activity: a longitudinal observational study. Moussiopoulou, J., Pross, B., Handrack, M., Keeser, D., Pogarell, O., Halle, M., Falkai, P., Scherr, J., Hasan, A. & Roeh, A. Eur J Appl Physiol (2023). 

The barriers to interprofessional care for cancer cachexia among Japanese healthcare providers: A nationwide survey. Naito, T., Wakabayashi, H., Aso, S., Konishi, M., Saitoh, M., Baracos, V. E., Coats, A. J., Anker, S. D., Sherman, L., Klompenhouwer, T., Shirotani, N., Inui, A. & Arai, H. J Cachexia Sarcopenia Muscle (2023). 

Prospective Cohort Study of Soluble Urokinase Plasminogen Activation Receptor and Cardiovascular Events in Patients With CKD. Sommerer, C., Muller-Krebs, S., Nadal, J., Schultheiss, U. T., Friedrich, N., Nauck, M., Schmid, M., Nusshag, C., Reiser, J., Eckardt, K. U., Zeier, M., Hayek, S. S. & German Chronic Kidney Disease, I. Kidney Int Rep 8, 2265-2275 (2023). 

Editorial: Advances in cardiovascular medical technology. Willy, K. & Doldi, P. M. Front Med Technol 5, 1309784 (2023). 

Disturbed endothelial cell signaling in tumor progression and therapy resistance. Fischer, A. & Alsina-Sanchis, E. Curr Opin Cell Biol 86, 102287 (2023). 

Intramolecular activity regulation of adhesion GPCRs in light of recent structural and evolutionary information. Kleinau, G., Ali, A. H., Wiechert, F., Szczepek, M., Schmidt, A., Spahn, C. M. T., Liebscher, I., Schoneberg, T. & Scheerer, P. Pharmacol Res 197, 106971 (2023). 

Case Report: Successful endovascular treatment of acute type A aortic dissection. Pitts, L., Heck, R., Montagner, M., Penkalla, A., Kofler, M., Falk, V., Kempfert, J. & Buz, S. Front Cardiovasc Med 10, 1299192 (2023). 

Depressive symptoms and anti-N-methyl-D-aspartate-receptor GluN1 antibody seropositivity in the PROSpective cohort with incident stroke. Sperber, P. S., Gebert, P., Broersen, L. H. A., Kufner, A., Huo, S., Piper, S. K., Teegen, B., Heuschmann, P. U., Pruss, H., Endres, M., Liman, T. G. & Siegerink, B. Brain Behav Immun Health 34, 100705 (2023). 

Implementation of the multielectrode radiofrequency-balloon in real-world clinical practice-operator learning curve and procedural outcome at a high-volume center. Zylla, M. M., Starrach, L., Rahm, A. K., Thomas, D., Frey, N. & Lugenbiel, P. Front Cardiovasc Med 10, 1208250 (2023).


Paper of the Month

Supervised exercise training in patients with advanced heart failure and left ventricular assist device: A multicentre randomized controlled trial (Ex-VAD trial). DZHK-authors: Anna Feuerstein, Felix Schönrath, Tim Friede, Marius Placzek, Doris Bach, Christoph Herrmann-Lingen, Michael Roden, Marcus Dörr, Stephan von Haehling, Martin Halle, Volkmar Falk, Burkert Pieske, Frank Edelmann. European Journal of Heart Failure, 2023.

Sudden cardiac death in childhood RASopathy-associated hypertrophic cardiomyopathy: Validation of the HCM risk-kids model and predictors of events. Boleti, O. D., Roussos, S., Norrish, G., Field, E., Oates, S., Tollit, J., Nepali, G., Bhole, V., Uzun, O., Daubeney, P. E. F., Stuart, G. A., Fernandes, P., McLeod, K., Ilina, M., Liaqath, M. N. A., Bharucha, T., Delle Donne, G., Brown, E., Linter, K., Khodaghalian, B., Jones, C., Searle, J., Mathur, S., Boyd, N., Reindhardt, Z., Duignan, S., Prendiville, T., Adwani, S., Zenker, M., Wolf, C. M. & Kaski, J. P. Int J Cardiol 393, 131405 (2023). 

Major in-hospital bleeding in patients with pulmonary embolism treated with systemic thrombolysis. Mavromanoli, A. C., Jimenez, D., Sanchez, O., Sobkowicz, B., Vanni, S., Kurzyna, M., Becattini, C., Pruszczyk, P., Wilkens, H., Bova, C., Tschope, C., Sawicka-Smiarowska, E., Grifoni, C., Kostrubiec, M., Torbicki, A., Meneveau, N., Kresoja, K. P. & Konstantinides, S. V. Thromb Res 231, 29-31 (2023). 

Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9. Thurkauf, M., Lin, S., Oliveri, F., Grimm, D., Platt, R. J. & Ruegg, M. A. Nat Commun 14, 6116 (2023). 

Artificial sweetener sucralose: a possible modulator of autoimmune diseases. Krankel, N. & Rauch-Kroehnert, U. Signal Transduct Target Ther 8, 377 (2023). 

UNICA - a novel single-stent, double-valve, heterotopic, cross-caval approach for severe tricuspid insufficiency. Sherif, M., Schmidt, A., Path, J. R., Rheinthaler, M. & Trippel, T. D. EuroIntervention (2023). 

Immunosuppression in Pediatric Heart Transplantation-The Leaner the Better? Attmann, T., Uebing, A. & Ensminger, S. M. Transplantation 108, e1-e2 (2024). 

Training in critical care cardiology: making the case for a standardized core curriculum. Binzenhofer, L., Thiele, H. & Lusebrink, E. Crit Care 27, 380 (2023). 

Mechanisms controlling cellular and systemic iron homeostasis. Galy, B., Conrad, M. & Muckenthaler, M. Nat Rev Mol Cell Biol (2023). 

Localized cardiomyocyte lipid accumulation is associated with slowed epicardial conduction in rats. Wells, S. P., Raaijmakers, A. J. A., Curl, C. L., O'Shea, C., Hayes, S., Mellor, K. M., Kalman, J. M., Kirchhof, P., Pavlovic, D., Delbridge, L. M. D. & Bell, J. R. J Gen Physiol 155 (2023). 

Improving sudden cardiac death risk stratification in hypertrophic cardiomyopathy using established clinical variables and genetic information. Amr, A., Koelemen, J., Reich, C., Sedaghat-Hamedani, F., Kayvanpour, E., Haas, J., Frese, K., Lehmann, D., Katus, H. A., Frey, N. & Meder, B. Clin Res Cardiol (2023). 

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma. Finotto, L., Cole, B., Giese, W., Baumann, E., Claeys, A., Vanmechelen, M., Decraene, B., Derweduwe, M., Dubroja Lakic, N., Shankar, G., Nagathihalli Kantharaju, M., Albrecht, J. P., Geudens, I., Stanchi, F., Ligon, K. L., Boeckx, B., Lambrechts, D., Harrington, K., Van Den Bosch, L., De Vleeschouwer, S., De Smet, F. & Gerhardt, H. EMBO Mol Med 15, e18144 (2023). 

Tricuspid Valve Academic Research Consortium Definitions for Tricuspid Regurgitation and Trial Endpoints. Hahn, R. T., Lawlor, M. K., Davidson, C. J., Badhwar, V., Sannino, A., Spitzer, E., Lurz, P., Lindman, B. R., Topilsky, Y., Baron, S. J., Chadderdon, S., Khalique, O. K., Tang, G. H. L., Taramasso, M., Grayburn, P. A., Badano, L., Leipsic, J., Lindenfeld, J., Windecker, S., Vemulapalli, S., Redfors, B., Alu, M. C., Cohen, D. J., Rodes-Cabau, J., Ailawadi, G., Mack, M., Ben-Yehuda, O., Leon, M. B. & Hausleiter, J. Eur Heart J (2023). 

Prognostic value of extended cardiac risk assessment before elective open abdominal aortic surgery. Sigl, M., Baumann, S., Konemann, A. S., Keese, M., Schwenke, K., Gerken, A. L. H., Durschmied, D. & Rosenkaimer, S. Herz (2023). 

Association of blood pressure and heart rate with carotid markers of vascular remodeling in the young: a case for early prevention. Buschges, J. C., Schmidt-Trucksass, A. & Neuhauser, H. J Hypertens 42, 153-160 (2024). 

Independent external validation of a stroke recurrence score in patients with embolic stroke of undetermined source. Ingwersen, T., Olma, M. C., Schlemm, E., Mayer, C., Cheng, B., Tutuncu, S., Kirchhof, P., Veltkamp, R., Rother, J., Laufs, U., Nabavi, D. G., Ntaios, G., Endres, M., Haeusler, K. G. & Thomalla, G. Neurol Res Pract 5, 51 (2023). 

Determinants of myocardial work indices in women. Jasaityte, R., Bajraktarevic, R., Blaschke-Waluga, D., Seeland, U., Regitz-Zagrosek, V., Landmesser, U., Stangl, K., Knebel, F., Stangl, V. & Brand, A. Echocardiography (2023). 

First experience with real-time magnetic resonance imaging-based investigation of respiratory influence on cardiac function in pediatric congenital heart disease patients with chronic right ventricular volume overload. Rower, L. M., Radke, K. L., Hussmann, J., Malik, H., Eichinger, M., Voit, D., Wielputz, M. O., Frahm, J., Klee, D. & Pillekamp, F. Pediatr Radiol 53, 2608-2621 (2023). 

Spontaneous blood pressure reduction of previously hypertensive patients as a symptom of central pulmonary artery embolism. Schell, R., Alban, F., Frey, N. & Erbel, C. Clin Res Cardiol (2023). 

Activation of neurokinin-III receptors modulates human atrial TASK-1 currents. Wiedmann, F., Paasche, A., Nietfeld, J., Kraft, M., Meyer, A. L., Warnecke, G., Karck, M., Frey, N. & Schmidt, C. J Mol Cell Cardiol 184, 26-36 (2023). 

An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions. Chua, W., Cardoso, V. R., Guasch, E., Sinner, M. F., Al-Taie, C., Brady, P., Casadei, B., Crijns, H., Dudink, E., Hatem, S. N., Kaab, S., Kastner, P., Mont, L., Nehaj, F., Purmah, Y., Reyat, J. S., Schotten, U., Sommerfeld, L. C., Zeemering, S., Ziegler, A., Gkoutos, G. V., Kirchhof, P. & Fabritz, L. Sci Rep 13, 16743 (2023). 

Brain endothelium: a nexus for cerebral small vessel disease. Dichgans, M., Faraci, F. M. & Network, B. Eur Heart J 44, 4211-4213 (2023). 

Disrupted Binding of Cystathionine gamma-Lyase to p53 Promotes Endothelial Senescence. Hu, J., Leisegang, M. S., Looso, M., Drekolia, M. K., Wittig, J., Mettner, J., Karantanou, C., Kyselova, A., Dumbovic, G., Li, X., Li, Y., Guenther, S., John, D., Siragusa, M., Zukunft, S., Oo, J. A., Wittig, I., Hille, S., Weigert, A., Knapp, S., Brandes, R. P., Muller, O. J., Papapetropoulos, A., Sigala, F., Dobreva, G., Kojonazarov, B., Fleming, I. & Bibli, S. I. Circ Res (2023). 

Behavior-related health risk factors, mental disorders and mortality after 20 years in a working aged general population sample. John, U., Rumpf, H. J., Hanke, M. & Meyer, C. Sci Rep 13, 16764 (2023). 

Utilization of an Artery-on-a-Chip to Unravel Novel Regulators and Therapeutic Targets in Vascular Diseases. Paloschi, V., Pauli, J., Winski, G., Wu, Z., Li, Z., Botti, L., Meucci, S., Conti, P., Rogowitz, F., Glukha, N., Hummel, N., Busch, A., Chernogubova, E., Jin, H., Sachs, N., Eckstein, H. H., Dueck, A., Boon, R. A., Bausch, A. R. & Maegdefessel, L. Adv Healthc Mater, e2302907 (2023). 

Impact of body mass index on worsening of diastolic function and impairment of left atrial strain in the general female urban population: a subanalysis of the Berlin female risk evaluation echocardiography follow-up study. Romero Dorta, E., Wolf, A., Hubscher, A., Blaschke-Waluga, D., Seeland, U., Crayen, C., Bischoff, S., Mattig, I., Dreger, H., Stangl, K., Regitz-Zagrosek, V., Landmesser, U., Knebel, F., Stangl, V. & Brand, A. Front Cardiovasc Med 10, 1242805 (2023). 

Outcome of Patients With Cardiogenic Shock and Previous Right Ventricular Impairment Represented by Decreased Tricuspid Annular Plane Systolic Excursion and Tricuspid Annular Plane Systolic Excursion to Pulmonary Artery Systolic Pressure Ratio. Rusnak, J., Schupp, T., Weidner, K., Ruka, M., Egner-Walter, S., Forner, J., Bertsch, T., Kittel, M., Mashayekhi, K., Tajti, P., Ayoub, M., Akin, I. & Behnes, M. Am J Cardiol 207, 431-440 (2023). 

Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism. Loos, M., Klampe, B., Schulze, T., Yin, X., Theofilatos, K., Ulmer, B. M., Schulz, C., Behrens, C. S., van Bergen, T. D., Adami, E., Maatz, H., Schweizer, M., Brodesser, S., Skryabin, B. V., Rozhdestvensky, T. S., Bodbin, S., Stathopoulou, K., Christ, T., Denning, C., Hubner, N., Mayr, M., Cuello, F., Eschenhagen, T. & Hansen, A. Stem Cell Reports 18, 2123-2137 (2023). 

Preinterventional frailty assessment in patients scheduled for cardiac surgery or transcatheter aortic valve implantation: a consensus statement of the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Preventive Cardiology (EAPC) of the European Society of Cardiology (ESC). Niebauer, J., Back, C., Bischoff-Ferrari, H. A., Dehbi, H. M., Szekely, A., Voller, H. & Sundermann, S. H. Eur J Prev Cardiol (2023). 

Preinterventional frailty assessment in patients scheduled for cardiac surgery or transcatheter aortic valve implantation: a consensus statement of the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Preventive Cardiology (EAPC) of the European Society of Cardiology (ESC). Sundermann, S. H., Back, C., Bischoff-Ferrari, H. A., Dehbi, H. M., Szekely, A., Voller, H. & Niebauer, J. Eur J Cardiothorac Surg 64 (2023). 

Transcatheter Pulmonary Valve Replacement Candidacy: Is Cardiovascular Magnetic Resonance Angiography Enough? Voges, I. & Krupickova, S. Am J Cardiol 207, 507-508 (2023). 

Obesity, metabolic health and clinical outcomes after incident cardiovascular disease: A nationwide population-based cohort study. Akyea, R. K., Ntaios, G. & Doehner, W. J Cachexia Sarcopenia Muscle (2023). 

Differentiating Macrovascular and Microvascular Ischemia Using Fractal Analysis of Dynamic Myocardial Perfusion Stress-CT. Michallek, F., Nakamura, S., Kurita, T., Ota, H., Nishimiya, K., Ogawa, R., Shizuka, T., Nakashima, H., Wang, Y. N., Ito, T., Sakuma, H., Dewey, M. & Kitagawa, K. Invest Radiol (2023). 

Detection of queuosine and queuosine precursors in tRNAs by direct RNA sequencing. Sun, Y., Piechotta, M., Naarmann-de Vries, I., Dieterich, C. & Ehrenhofer-Murray, A. E. Nucleic Acids Res 51, 11197-11212 (2023). 

Starving out brain tumors: a reprogrammed lysine catabolism serves as a novel target for glioblastoma treatment. Gul, D., Kramer, O. H. & Reinhardt, C. Signal Transduct Target Ther 8, 401 (2023). 

Cardiovascular Risk in Childhood is Associated With Carotid Intima-Media Thickness and Stiffness in Adolescents and Young Adults: The KiGGS Cohort. Konigstein, K., Buschges, J. C., Schmidt-Trucksass, A. & Neuhauser, H. J Adolesc Health 74, 123-129 (2024). 

Author Correction: Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation. Melo, U. S., Jatzlau, J., Prada-Medina, C. A., Flex, E., Hartmann, S., Ali, S., Schopflin, R., Bernardini, L., Ciolfi, A., Moeinzadeh, M. H., Klever, M. K., Altay, A., Vallecillo-Garcia, P., Carpentieri, G., Delledonne, M., Ort, M. J., Schwestka, M., Ferrero, G. B., Tartaglia, M., Brusco, A., Gossen, M., Strunk, D., Geissler, S., Mundlos, S., Stricker, S., Knaus, P., Giorgio, E. & Spielmann, M. Nat Commun 14, 6301 (2023). 

Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis. Perakakis, N., Bornstein, S. R., Birkenfeld, A. L., Linkermann, A., Demir, M., Anker, S. D., Filippatos, G., Pitt, B., Rossing, P., Ruilope, L. M., Kolkhof, P., Lawatscheck, R., Scott, C., Bakris, G. L., Fidelio, D. K. D. & investigators, F.-D. Diabetes Obes Metab 26, 191-200 (2024). 

Hemodynamic and Stress Response After Sound Intervention with Different Headphone Systems: A Double-Blind Randomized Study in Healthy Volunteers Working in the Health Care Sector. Hohneck, A., Reyser, C., Usselmann, R., Heinemann, L., Weingaertner, S., Reckling, H., Schumacher, G., Burkholder, I., Merx, K., Hofmann, W. K. & Hofheinz, R. D. J Integr Complement Med (2023). 

Immune signatures of checkpoint inhibitor-induced autoimmunity - a focus on neurotoxicity. Muller-Jensen, L., Schulz, A. R., Mei, H. E., Mohr, R., Ulrich, C., Knape, P., Frost, N., Frischbutter, S., Kunkel, D., Schinke, C., Roque, L. G., Maierhof, S. K., Nickel, F. T., Heinzerling, L., Endres, M., Boehmerle, W., Huehnchen, P. & Knauss, S. Neuro Oncol (2023). 

Reply: Similarities to Pacing-Induced Heart Failure. Reil, J. C., Eitel, I. & Stiermaier, T. J Am Coll Cardiol 82, e145 (2023). 

Association of a healthy lifestyle with mortality in older people. Robb, C., Carr, P. R., Ball, J., Owen, A., Beilin, L. J., Newman, A. B., Nelson, M. R., Reid, C. M., Orchard, S. G., Neumann, J. T., Tonkin, A. M., Wolfe, R. & McNeil, J. J. BMC Geriatr 23, 646 (2023). 

Preoperative arterial lactate and outcome after surgery for type A aortic dissection: The ERTAAD multicenter study. Biancari, F., Nappi, F., Gatti, G., Perrotti, A., Herve, A., Rosato, S., D'Errigo, P., Pettinari, M., Peterss, S., Buech, J., Juvonen, T., Jormalainen, M., Mustonen, C., Demal, T., Conradi, L., Pol, M., Kacer, P., Dell'Aquila, A. M., Wisniewski, K., Vendramin, I., Piani, D., Ferrante, L., Makikallio, T., Quintana, E., Pruna-Guillen, R., Fiore, A., Folliguet, T., Mariscalco, G., Acharya, M., Field, M., Kuduvalli, M., Onorati, F., Rossetti, C., Gerelli, S., Di Perna, D., Mazzaro, E., Pinto, A. G., Lega, J. R. & Rinaldi, M. Heliyon 9, e20702 (2023). 

[T-TEER: description of a development process]. Doldi, P. M., Stolz, L., Weckbach, L. T. & Hausleiter, J. Herz 48, 448-455 (2023). 

Kinin B1 receptor modulates glucose homeostasis and physical exercise capacity by altering adrenal catecholamine synthesis and secretion. Fernandes Gregnani, M., Budu, A., Batista, R. O., Ornellas, F. H., Estrela, G. R., Arruda, A. C., Freitas Lima, L. C., Kremer, J. L., Favaroni Mendes, L. A., Casarini, D. E., Lotfi, C. F. P., Oyama, L. M., Bader, M. & Araujo, R. C. Mol Cell Endocrinol 579, 112085 (2024). 

Correlates of Skeletal Muscle Mass and Differences Between Novel Subtypes in Recent-onset Diabetes. Herder, C., Maalmi, H., Saatmann, N., Zaharia, O. P., Strassburger, K., Burkart, V., Norman, K. & Roden, M. J Clin Endocrinol Metab (2023). 

Genetic Variants in WNT16 and PKD2L1 Locus Affect Heel Ultrasound Bone Stiffness: Analyses from the General Population and Patients Evaluated for Osteoporosis. Kragl, A., Hannemann, A., Nauck, M., Volker, U., Siggelkow, H., Teumer, A. & Tzvetkov, M. V. Calcif Tissue Int 113, 540-551 (2023). 

Multiphoton In Vivo Microscopy of Embryonic Thrombopoiesis Reveals the Generation of Platelets through Budding. Liu, H., Ishikawa-Ankerhold, H., Winterhalter, J., Lorenz, M., Vladymyrov, M., Massberg, S., Schulz, C. & Orban, M. Cells 12 (2023). 

Platelet Count During Course of Cardiogenic Shock. Schupp, T., Rusnak, J., Forner, J., Dudda, J., Bertsch, T., Behnes, M. & Akin, I. ASAIO J (2023). 

Systemic Effects of Homoarginine Supplementation on Arginine Metabolizing Enzymes in Rats with Heart Failure with Preserved Ejection Fraction. Buttner, P., Werner, S., Bottner, J., Ossmann, S., Schwedhelm, E. & Thiele, H. Int J Mol Sci 24 (2023). 

Multi-Omic Candidate Screening for Markers of Severe Clinical Courses of COVID-19. Dutsch, A., Uhlig, C., Bock, M., Graesser, C., Schuchardt, S., Uhlig, S., Schunkert, H., Joner, M., Holdenrieder, S. & Lechner, K. J Clin Med 12 (2023). 

Left Atrial Posterior Wall Isolation with Pulsed Field Ablation in Persistent Atrial Fibrillation. Gunawardene, M. A., Frommeyer, G., Ellermann, C., Jularic, M., Leitz, P., Hartmann, J., Lange, P. S., Anwar, O., Rath, B., Wahedi, R., Eckardt, L. & Willems, S. J Clin Med 12 (2023). 

Diagnostic sample transport via pneumatic tube systems: data logger and their algorithms are sensitive to transport effects. Ninnemann, J., Zylla, S., Streichert, T., Otto, B., Haenel, M., Nauck, M. & Petersmann, A. Clin Chem Lab Med (2023). 

Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction. Bachamanda Somesh, D., Klose, K., Maring, J. A., Kunkel, D., Jurchott, K., Protze, S. I., Klein, O., Nebrich, G., Becker, M., Kruger, U., Nazari-Shafti, T. Z., Falk, V., Kurtz, A., Gossen, M. & Stamm, C. Stem Cell Res Ther 14, 296 (2023). 

Prevalence of Overweight and Obesity, Its Complications, and Progression in a 10-Year Follow-Up in the Gutenberg Health Study (GHS). Falter, T., Hennige, A. M., Schulz, A., Gieswinkel, A., Lotz, J., Rossmann, H., Beutel, M., Michal, M., Pfeiffer, N., Schmidtmann, I., Munzel, T., Wild, P. S. & Lackner, K. J. Obes Facts 17, 12-23 (2024). 

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators. Kuhnisch, J., Theisen, S., Dartsch, J., Fritsche-Guenther, R., Kirchner, M., Obermayer, B., Bauer, A., Kahlert, A. K., Rothe, M., Beule, D., Heuser, A., Mertins, P., Kirwan, J. A., Berndt, N., MacRae, C. A., Hubner, N. & Klaassen, S. Cardiovasc Res (2023). 

Outcomes of endovascular treatment for popliteal artery disease. Muller, A. M., Lohn-Kannengiesser, L., Bradaric, C., Dirschinger, R., Koppara, T., Bergmann, K., Kehl, V., Cassese, S., Xhepa, E., Kastrati, A., Laugwitz, K. L. & Ibrahim, T. Vasa (2023). 

Editorial: Multimodality imaging of left ventricular assist devices: applications in advanced heart failure. Pergola, V., Cameli, M., Dandel, M. & Soliman-Aboumarie, H. Front Cardiovasc Med 10, 1277563 (2023). 

Towards a new classification of atrial fibrillation detected after a stroke or a transient ischaemic attack. Sposato, L. A., Field, T. S., Schnabel, R. B., Wachter, R., Andrade, J. G. & Hill, M. D. Lancet Neurol 23, 110-122 (2024). 

Safety of dobutamine or adenosine stress cardiac magnetic resonance imaging in patients with left ventricular thrombus. Weberling, L. D., Seitz, S., Salatzki, J., Ochs, A., Heins, J., Haney, A. C., Siry, D., Frey, N., Andre, F. & Steen, H. Clin Res Cardiol (2023). 

[Clinical application of large language models : Does ChatGPT replace medical report formulation? An experience report]. Zernikow, J., Grassow, L., Groschel, J., Henrion, P., Wetzel, P. J. & Spethmann, S. Inn Med (Heidelb) 64, 1058-1064 (2023). 

Proposed diagnostic criteria for arrhythmogenic cardiomyopathy: European Task Force consensus report. Corrado, D., Anastasakis, A., Basso, C., Bauce, B., Blomstrom-Lundqvist, C., Bucciarelli-Ducci, C., Cipriani, A., De Asmundis, C., Gandjbakhch, E., Jimenez-Jaimez, J., Kharlap, M., McKenna, W. J., Monserrat, L., Moon, J., Pantazis, A., Pelliccia, A., Perazzolo Marra, M., Pillichou, K., Schulz-Menger, J., Jurcut, R., Seferovic, P., Sharma, S., Tfelt-Hansen, J., Thiene, G., Wichter, T., Wilde, A. & Zorzi, A. Int J Cardiol 395, 131447 (2024). 

SGLT2 inhibitors on top of intravenous iron in patients with heart failure and iron deficiency: any incremental effect? Savarese, G., Butler, J., Ponikowki, P. & Anker, S. D. Eur J Heart Fail (2023). 

Sodium-glucose cotransporter 2 inhibitors on top of intravenous iron in patients with heart failure and iron deficiency: Any incremental effect? Savarese, G., Butler, J., Ponikowki, P. & Anker, S. D. Eur J Heart Fail 25, 2199-2201 (2023). 

First experiences of ultrasound vector flow imaging at the femoropopliteal artery in peripheral arterial disease. Shchetynska-Marinova, T., Gerdes, L., Hohneck, A. L., Winter, L., Amendt, K., Schwenke, K., Gerken, A. L. H., Du, Y., Durschmied, D. & Sigl, M. Vasa (2023). 

The challenges of research data management in cardiovascular science: a DGK and DZHK position paper-executive summary. Steffens, S., Schroder, K., Kruger, M., Maack, C., Streckfuss-Bomeke, K., Backs, J., Backofen, R., Baessler, B., Devaux, Y., Gilsbach, R., Heijman, J., Knaus, J., Kramann, R., Linz, D., Lister, A. L., Maatz, H., Maegdefessel, L., Mayr, M., Meder, B., Nussbeck, S. Y., Rog-Zielinska, E. A., Schulz, M. H., Sickmann, A., Yigit, G. & Kohl, P. Clin Res Cardiol (2023). 

Differential Effects of Erythropoietin Administration and Overexpression on Venous Thrombosis in Mice. Stockhausen, S., Kilani, B., Schubert, I., Steinsiek, A. L., Chandraratne, S., Wendler, F., Eivers, L., von Bruhl, M. L., Massberg, S., Ott, I. & Stark, K. Thromb Haemost (2023). 

The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats. Haduch, A., Bromek, E., Kuban, W., Basinska-Ziobron, A., Danek, P. J., Alenina, N., Bader, M. & Daniel, W. A. Pharmacol Rep 75, 1522-1532 (2023). 

Combined telemonitoring and telecoaching for heart failure improves outcome. Knoll, K., Rosner, S., Gross, S., Dittrich, D., Lennerz, C., Trenkwalder, T., Schmitz, S., Sauer, S., Hentschke, C., Dorr, M., Kloss, C., Schunkert, H. & Reinhard, W. NPJ Digit Med 6, 193 (2023). 

Machine learning using multimodal and autonomic nervous system parameters predicts clinically apparent stroke-associated pneumonia in a development and testing study. Nelde, A., Krumm, L., Arafat, S., Hotter, B., Nolte, C. H., Scheitz, J. F., Klammer, M. G., Kramer, M., Scheib, F., Endres, M., Meisel, A. & Meisel, C. J Neurol (2023). 

Calibrating machine learning approaches for probability estimation: A comprehensive comparison. Ojeda, F. M., Jansen, M. L., Thiery, A., Blankenberg, S., Weimar, C., Schmid, M. & Ziegler, A. Stat Med 42, 5451-5478 (2023). 

Associations of C-reactive protein with depressive symptoms over time after mild to moderate ischemic stroke in the PROSCIS-B cohort. Schaeff, V. L. K., Sperber, P. S., Piper, S. K., Giesers, N. K., Gertz, K., Heuschmann, P. U., Endres, M. & Liman, T. G. J Neurol (2023). 

Ethical and coordinative challenges in setting up a national cohort study during the COVID-19 pandemic in Germany. Tilch, K., Hopff, S. M., Appel, K., Kraus, M., Lorenz-Depiereux, B., Pilgram, L., Anton, G., Berger, S., Geisler, R., Haas, K., Illig, T., Krefting, D., Lorbeer, R., Mitrov, L., Muenchhoff, M., Nauck, M., Pley, C., Reese, J. P., Rieg, S., Scherer, M., Stecher, M., Stellbrink, C., Valentin, H., Winter, C., Witzenrath, M. & Vehreschild, J. J. BMC Med Ethics 24, 84 (2023). 

Alternative minimally invasive surgical explantation techniques for failed transcatheter mitral valve repair devices. Akansel, S., Kofler, M., Van Praet, K. M., Sundermann, S. H., Unbehaun, A., Jacobs, S., Falk, V. & Kempfert, J. JTCVS Tech 21, 65-71 (2023). 

Left atrial area index provides the best prediction of atrial fibrillation in ischemic stroke patients: results from the LAETITIA observational study. Alonso, A., Kraus, J., Ebert, A., Nikolayenko, V., Kruska, M., Sandikci, V., Lesch, H., Duerschmied, D., Platten, M., Baumann, S., Szabo, K., Akin, I. & Fastner, C. Front Neurol 14, 1237550 (2023). 

Using reflectometry to minimize the dependence of fluorescence intensity on optical absorption and scattering. Arias, A., Anastasopoulou, M., Gorpas, D. & Ntziachristos, V. Biomed Opt Express 14, 5499-5511 (2023). 

Very high-power short-duration catheter ablation for treatment of cardiac arrhythmias: Insights from the FAST and FURIOUS study series. Heeger, C. H., Kuck, K. H. & Tilz, R. R. J Cardiovasc Electrophysiol (2023). 

A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS. Johann, L., Soldati, S., Muller, K., Lampe, J., Marini, F., Klein, M., Schramm, E., Ries, N., Schelmbauer, C., Palagi, I., Karram, K., Assmann, J. C., Khan, M. A., Wenzel, J., Schmidt, M. H., Korbelin, J., Schluter, D., van Loo, G., Bopp, T., Engelhardt, B., Schwaninger, M. & Waisman, A. J Clin Invest 133 (2023). 

Transcatheter Mitral Valve Replacement: Endocarditis Surgically Treated. Pommert, N. S., Puehler, T., Meier, D., Seoudy, H., Sathananthan, J., Sellers, S. L., Both, M., Saad, M., Frank, D. & Lutter, G. JACC Cardiovasc Interv (2023). 

mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy. Riedmayr, L. M., Hinrichsmeyer, K. S., Thalhammer, S. B., Mittas, D. M., Karguth, N., Otify, D. Y., Bohm, S., Weber, V. J., Bartoschek, M. D., Splith, V., Brummer, M., Ferreira, R., Boon, N., Wogenstein, G. M., Grimm, C., Wijnholds, J., Mehlfeld, V., Michalakis, S., Fenske, S., Biel, M. & Becirovic, E. Nat Commun 14, 6578 (2023). 

Systematic Assessment of Shock Severity in Postoperative Cardiac Surgery Patients. Roeschl, T., Hinrichs, N., Hommel, M., Pfahringer, B., Balzer, F., Falk, V., O'Brien, B., Ott, S. C., Potapov, E., Schoenrath, F. & Meyer, A. J Am Coll Cardiol 82, 1691-1706 (2023). 

[Utilization of video consultation in cardiovascular lipid treatment]. Schuch, A., Walther, P., Timm, L., Steinbach, K., Haneklaus, L., Munzel, T., Prochaska, J. H. & Wild, P. S. Herz (2023). 

Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome. Costeira, R., Evangelista, L., Wilson, R., Yan, X., Hellbach, F., Sinke, L., Christiansen, C., Villicana, S., Masachs, O. M., Tsai, P. C., Mangino, M., Menni, C., Berry, S. E., Beekman, M., van Heemst, D., Slagboom, P. E., Heijmans, B. T., Suhre, K., Kastenmuller, G., Gieger, C., Peters, A., Small, K. S., Linseisen, J., Waldenberger, M. & Bell, J. T. Clin Epigenetics 15, 166 (2023). 

Intravital Imaging of Thrombosis Models in Mice. Kiouptsi, K., Casari, M., Mandel, J., Gao, Z. & Deppermann, C. Hamostaseologie 43, 348-359 (2023). 

Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease (GCKD) cohort. Reimer, K. C., Nadal, J., Meiselbach, H., Schmid, M., Schultheiss, U. T., Kotsis, F., Stockmann, H., Friedrich, N., Nauck, M., Krane, V., Eckardt, K. U., Schneider, M. P., Kramann, R., Floege, J., Saritas, T. & investigators, G. s. Bone Res 11, 52 (2023). 

Circulating miR-133a-3p defines a low-risk subphenotype in patients with heart failure and central sleep apnea: a decision tree machine learning approach. de Gonzalo-Calvo, D., Martinez-Camblor, P., Belmonte, T., Barbe, F., Duarte, K., Cowie, M. R., Angermann, C. E., Korte, A., Riedel, I., Labus, J., Koenig, W., Zannad, F., Thum, T. & Bar, C. J Transl Med 21, 742 (2023). 

Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial. Kopczak, A., Stringer, M. S., van den Brink, H., Kerkhofs, D., Blair, G. W., van Dinther, M., Reyes, C. A., Garcia, D. J., Onkenhout, L., Wartolowska, K. A., Thrippleton, M. J., Kampaite, A., Duering, M., Staals, J., Lesnik-Oberstein, S., Muir, K. W., Middeke, M., Norrving, B., Bousser, M. G., Mansmann, U., Rothwell, P. M., Doubal, F. N., van Oostenbrugge, R., Biessels, G. J., Webb, A. J. S., Wardlaw, J. M., Dichgans, M. & collaborators, T. R.-S. Lancet Neurol 22, 991-1004 (2023). 

Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES. Schwarzova, B., Studemann, T., Sonmez, M., Rossinger, J., Pan, B., Eschenhagen, T., Stenzig, J., Wiegert, J. S., Christ, T. & Weinberger, F. Pflugers Arch (2023). 

Prognostic value of negative stress cardiac magnetic resonance imaging in patients with moderate-severe coronary artery stenosis. Haney, A. C., Salatzki, J., Hund, H., Friedrich, M. G., Giannitsis, E., Frey, N., Steen, H., Lossnitzer, D., Riffel, J. & Andre, F. Front Cardiovasc Med 10, 1264374 (2023). 

Mechanical circulatory support with ECMELLA approach in severe cardiogenic shock patients-state of the art. Nersesian, G. & Potapov, E. J Thorac Dis 15, 4555-4557 (2023). 

The Platelet Anaphylatoxin Receptor C5aR1 (CD88) Is a Promising Target for Modulating Vessel Growth in Response to Ischemia (a). Nording, H., Baron, L., Lubken, A., Emami, H., von Esebeck, J., Meusel, M., Sadik, C., Schanze, N., Duerschmied, D., Kohl, J., Munch, G. & Langer, H. F. TH Open 7, e289-e293 (2023). 

Bioactive adrenomedullin (bio-ADM) is associated with endothelial dysfunction in infants and children with complex congenital heart disease undergoing open-heart surgery on cardiopulmonary bypass. Schaefer, M., Stein, A., Ruf, B., Balling, G., Palm, J., Simmelbauer, A., Cleuziou, J., Sander, M., Auer, J., Borgmann, K., Struck, J., Hartmann, O., Schulte, J., Horer, J., Tassani-Prell, P., Ewert, P., Holdenrieder, S. & Wolf, C. M. Clin Chem Lab Med (2023). 

Outcomes After Complex PCI With COMBO Stent Implantation: Insights from a Real-World Pooled Dataset. Spirito, A., Nussbaum, J., Sartori, S., Vogel, B., Abizaid, A., Cao, D., Christiansen, E. H., Colombo, A., de Winter, R. J., Haude, M., Kamaleldin, K., Jakobsen, L., Jensen, L. O., Krucoff, M. W., Landmesser, U., Nardin, M., Saito, S., Smith, K. F., Suryapranata, H., De Luca, G., Dangas, G., Mehran, R. & Mega, C. C. Am J Cardiol 209, 52-54 (2023). 

Incidence of systemic inflammatory response syndrome and patient outcome following transcatheter edge-to-edge mitral valve repair. Syryca, F., Pellegrini, C., Gollreiter, M., Nicol, P., Mayr, N. P., Alvarez-Covarrubias, H. A., Altaner, N., Rheude, T., Holdenrieder, S., Schunkert, H., Kastrati, A., Joner, M., Xhepa, E. & Trenkwalder, T. Clin Res Cardiol (2023). 

Accelerated 2D Cartesian MRI with an 8-channel local B(0) coil array combined with parallel imaging. Tian, R., Uecker, M., Davids, M., Thielscher, A., Buckenmaier, K., Holder, O., Steffen, T. & Scheffler, K. Magn Reson Med 91, 443-465 (2024). 

Spotty calcium deposits within acute coronary syndrome (ACS)-causing culprit lesions impact inflammatory vessel-wall interactions and are associated with higher cardiovascular event rates at one year follow-up: Results from the prospective translational OPTICO-ACS study program. Nelles, G., Abdelwahed, Y. S., Alyaqoob, A., Seppelt, C., Stahli, B. E., Meteva, D., Krankel, N., Haghikia, A., Skurk, C., Dreger, H., Knebel, F., Trippel, T. D., Krisper, M., Sieronski, L., Gerhardt, T., Zanders, L., Klotsche, J., Landmesser, U., Joner, M. & Leistner, D. M. Atherosclerosis 385, 117284 (2023). 

The unique biomechanics of intermediate filaments - From single filaments to cells and tissues. Rolleke, U., Kumari, P., Meyer, R. & Koster, S. Curr Opin Cell Biol 85, 102263 (2023). 

Impaired T cell IRE1alpha/XBP1 signaling directs inflammation in experimental heart failure with preserved ejection fraction. Smolgovsky, S., Bayer, A. L., Kaur, K., Sanders, E., Aronovitz, M., Filipp, M. E., Thorp, E. B., Schiattarella, G. G., Hill, J. A., Blanton, R. M., Cubillos-Ruiz, J. R. & Alcaide, P. J Clin Invest 133 (2023). 

Comprehensive Vasodilation in Women with Acute Heart Failure: Novel Insights from the GALACTIC randomized controlled trial. Wussler, D., Belkin, M., Maeder, M. T., Walter, J., Shrestha, S., Kupska, K., Stierli, M., Flores, D., Kozhuharov, N., Gualandro, D. M., de Oliveira Junior, M. T., Sabti, Z., Noveanu, M., Socrates, T., Bayes-Genis, A., Sionis, A., Simon, P., Michou, E., Gujer, S., Gori, T., Wenzel, P., Pfister, O., Arenja, N., Kobza, R., Rickli, H., Breidthardt, T., Munzel, T., Mueller, C. & Investigators, G. Eur J Heart Fail (2023). 

Complications in patients with cardiogenic shock on veno-arterial extracorporeal membrane oxygenation therapy: distribution and relevance. Results from an international, multicentre cohort study. Beer, B. N., Kellner, C., Gossling, A., Sundermeyer, J., Besch, L., Dettling, A., Kirchhof, P., Blankenberg, S., Bernhardt, A. M., Brunner, S., Colson, P., Eckner, D., Frank, D., Eitel, I., Frey, N., Eden, M., Graf, T., Kupka, D., Landmesser, U., Majunke, N., Maniuc, O., Mobius-Winkler, S., Morrow, D. A., Mourad, M., Noel, C., Nordbeck, P., Orban, M., Pappalardo, F., Patel, S. M., Pauschinger, M., Reichenspurner, H., Schulze, P. C., Schwinger, R. H. G., Wechsler, A., Skurk, C., Thiele, H., Varshney, A. S., Sag, C. M., Krais, J., Westermann, D. & Schrage, B. Eur Heart J Acute Cardiovasc Care (2023). 

Implantation depth of balloon-expandable transcatheter heart valves and risks for permanent pacemaker implantation and midterm adverse events. Pellegrini, C., Freissmuth, M., Rheude, T., Graas, D., Mayr, N. P., Syryca, F., Alvarez-Covarrubias, H. A., Fetcu, A., Hubner, J., Lennerz, C., Schunkert, H., Kastrati, A., Xhepa, E. & Joner, M. Catheter Cardiovasc Interv (2023). 

Absence of visible infarction on cardiac magnetic resonance imaging despite the established diagnosis of myocardial infarction by 4th UDMI definition. Salatzki, J., Giannitsis, E., Hegenbarth, A., Mueller-Hennessen, M., Andre, F., Frey, N. & Biener, M. Eur Heart J Acute Cardiovasc Care (2023). 

Photon-counting detector CT-based virtual monoenergetic reconstructions: repeatability and reproducibility of radiomics features of an organic phantom and human myocardium. Wolf, E. V., Muller, L., Schoepf, U. J., Fink, N., Griffith, J. P., 3rd, Zsarnoczay, E., Baruah, D., Suranyi, P., Kabakus, I. M., Halfmann, M. C., Emrich, T., Varga-Szemes, A. & O'Doherty, J. Eur Radiol Exp 7, 59 (2023). 

The natural history of periodontal disease-Part 2: In populations with access to dental care: The Studies of Health in Pomerania (SHIP). Kocher, T., Meisel, P., Biffar, R., Volzke, H. & Holtfreter, B. Periodontol 2000 (2023). 

Be aware and hit hard and early: oesophageal lesions after atrial fibrillation ablation. Tilz, R. R. & Heeger, C. H. Eur Heart J (2023). 

Deep Learning-Based Automated Labeling of Coronary Segments for Structured Reporting of Coronary Computed Tomography Angiography in Accordance With Society of Cardiovascular Computed Tomography Guidelines. Brandt, V., Fischer, A., Schoepf, U. J., Bekeredjian, R., Tesche, C., Aquino, G. J., O'Doherty, J., Sharma, P., Gulsun, M. A., Klein, P., Ali, A., Few, W. E., Emrich, T., Varga-Szemes, A. & Decker, J. A. J Thorac Imaging (2023). 

Diagnostic and prognostic value of the sex-specific 99th percentile of four high-sensitivity cardiac troponin assays in patients with suspected myocardial infarction. Lehmacher, J., Sorensen, N. A., Twerenbold, R., Gossling, A., Haller, P. M., Hartikainen, T. S., Schock, A., Toprak, B., Zeller, T., Westermann, D. & Neumann, J. T. Eur Heart J Acute Cardiovasc Care (2023). 

The Muscarinic Acetylcholine M(2) Receptor-Induced Nitration of p190A by eNOS Increases RhoA Activity in Cardiac Myocytes. Levay, M. K., Throm, L., Bahrami, N. & Wieland, T. Cells 12 (2023). 

The Impact of the Nervous System on Arteries and the Heart: The Neuroimmune Cardiovascular Circuit Hypothesis. Mohanta, S. K., Sun, T., Lu, S., Wang, Z., Zhang, X., Yin, C., Weber, C. & Habenicht, A. J. R. Cells 12 (2023). 

Late-Onset Prosthetic Endocarditis with Paraaortic Abscess Caused by Cutibacterium acnes. Velollari, O., Reinhardt, C. M., Knorr, M., Schnitzler, K., Graafen, D., Miederer, M., von Bardeleben, R. S., Munzel, T., Schmidt, K. H., Giebels, C., Schafers, H. J. & Hobohm, L. Infect Dis Rep 15, 635-641 (2023). 

Anorexia of aging: An international assessment of healthcare providers' knowledge and practice gaps. Aprahamian, I., Coats, A. J., Morley, J. E., Klompenhouwer, T., Anker, S. D., International Advisory, B., Regional Advisory Boards for North America, L. A. E. & Japan. J Cachexia Sarcopenia Muscle (2023). 

Patients with Advanced Pancreatic Cancer Treated with Mistletoe and Hyperthermia in Addition to Palliative Chemotherapy: A Retrospective Single-Center Analysis. Hohneck, A. L., Sadikaj, L., Heinemann, L., Schroeder, M., Riess, H., Gerhards, A., Burkholder, I., Heckel-Reusser, S., Gottfried, J. & Hofheinz, R. D. Cancers (Basel) 15 (2023). 

Mammalian target of rapamycin inhibition impacts energy homeostasis and induces sex-specific body weight loss in humans. Mannaa, M., Pfennigwerth, P., Fielitz, J., Gollasch, M. & Boschmann, M. J Cachexia Sarcopenia Muscle (2023). 

Temporary Mechanical Circulatory Support in Cardiogenic Shock Patients after Cardiac Procedures: Selection Algorithm and Weaning Strategies. Nersesian, G., Ott, S., Fardman, A., Lanmueller, P., Lewin, D., Bernhardt, A., Emrich, F., Faerber, G., Szabo, G., Oezkur, M., Panholzer, B., Rojas, S. V., Saeed, D., Schmack, B., Warnecke, G., Zimpfer, D., Grubitzsch, H., Falk, V. & Potapov, E. Life (Basel) 13 (2023). 

Amino acid auxotrophies in human gut bacteria are linked to higher microbiome diversity and long-term stability. Starke, S., Harris, D. M. M., Zimmermann, J., Schuchardt, S., Oumari, M., Frank, D., Bang, C., Rosenstiel, P., Schreiber, S., Frey, N., Franke, A., Aden, K. & Waschina, S. ISME J 17, 2370-2380 (2023). 

Depression, anxiety, and quality of life as predictors of rehospitalization in patients with chronic heart failure. Veskovic, J., Cvetkovic, M., Tahirovic, E., Zdravkovic, M., Apostolovic, S., Kosevic, D., Loncar, G., Obradovic, D., Matic, D., Ignjatovic, A., Cvetkovic, T., Posch, M. G., Radenovic, S., Ristic, A. D., Dokic, D., Milosevic, N., Panic, N. & Dungen, H. D. BMC Cardiovasc Disord 23, 525 (2023). 

Is Marfan Syndrome Associated with Primary Structural Changes in the Left Atrium? Zhang, K., Ernst, L., Schobert, I., Philipp, K., Boning, G., Heinzel, F. R., Boldt, L. H. & Gehle, P. Diagnostics (Basel) 13 (2023). 

Health Status After Transcatheter Tricuspid-Valve Repair in Patients With Severe Tricuspid Regurgitation. Arnold, S. V., Goates, S., Sorajja, P., Adams, D. H., von Bardeleben, R. S., Kapadia, S. R., Cohen, D. J. & Investigators, T. P. T. J Am Coll Cardiol 83, 1-13 (2024). 

Detection of brain lesions after catheter ablation depends on imaging criteria - Insights from AXAFA-AFNET 5 trial. Haeusler, K. G., Eichner, F. A., Heuschmann, P. U., Fiebach, J. B., Engelhorn, T., Callans, D., De Potter, T., Debruyne, P., Scherr, D., Hindricks, G., Al-Khalidi, H. R., Mont, L., Kim, W. Y., Piccini, J. P., Schotten, U., Themistoclakis, S., Di Biase, L. & Kirchhof, P. Europace (2023). 

Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodeling via chemerin. Man, A. W. C., Zhou, Y., Reifenberg, G., Camp, A., Munzel, T., Daiber, A., Xia, N. & Li, H. Cardiovasc Res (2023). 

Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin. Man, A. W. C., Zhou, Y., Reifenberg, G., Camp, A., Munzel, T., Daiber, A., Xia, N. & Li, H. Cardiovasc Res 119, 2755-2769 (2023). 

Comparing a Direct Whole Blood Enzymatic Assay With High-Performance Liquid Chromatography for HbA(1c) Measurement. Zechmeister, B., Fischer, A. & Eidizadeh, A. J Diabetes Sci Technol, 19322968231205842 (2023). 

Association of sex hormones and sex hormone-binding globulin with liver fat in men and women: an observational and Mendelian randomization study. Cai, X., Thorand, B., Hohenester, S., Prehn, C., Cecil, A., Adamski, J., Zeller, T., Dennis, A., Banerjee, R., Peters, A., Yaghootkar, H. & Nano, J. Front Endocrinol (Lausanne) 14, 1223162 (2023). 

Pushing the boundaries of innovation: the potential of ex vivo organ perfusion from an interdisciplinary point of view. Iske, J., Schroeter, A., Knoedler, S., Nazari-Shafti, T. Z., Wert, L., Roesel, M. J., Hennig, F., Niehaus, A., Kuehn, C., Ius, F., Falk, V., Schmelzle, M., Ruhparwar, A., Haverich, A., Knosalla, C., Tullius, S. G., Vondran, F. W. R. & Wiegmann, B. Front Cardiovasc Med 10, 1272945 (2023). 

Increased risk of dementia differs across cardiovascular diseases and types of dementia - Data from a nationwide study. Kauko, A., Engler, D., Niiranen, T., Ortega-Alonso, A. & Schnabel, R. B. J Intern Med (2023). 

Effects of SARS-COV-2 infection on outcomes in patients hospitalized for acute cardiac conditions. A prospective, multicenter cohort study (Swiss Cardiovascular SARS-CoV-2 Consortium). Koskinas, K. C., Twerenbold, R., Carballo, D., Matter, C. M., Cook, S., Heg, D., Frenk, A., Windecker, S., Osswald, S., Luscher, T. F. & Mach, F. Front Cardiovasc Med 10, 1203427 (2023). 

Interaction of Heart Failure and Stroke: A clinical consensus statement of the ESC Council on Stroke, the Heart Failure Association (HFA) and the ESC Working Group on Thrombosis. Doehner, W., Bohm, M., Boriani, G., Christersson, C., Coats, A. J., Haeusler, K. G., Jones, I. D., Lip, G. Y. H., Metra, M., Ntaios, G., Savarese, G., Shantsila, E., Vilahur, G. & Rosano, G. Eur J Heart Fail (2023). 

DNA-pools targeted-sequencing as a robust cost-effective method to detect rare variants: Application to dilated cardiomyopathy genetic diagnosis. Perret, C., Proust, C., Esslinger, U., Ader, F., Haas, J., Pruny, J. F., Isnard, R., Richard, P., Tregouet, D. A., Charron, P., Cambien, F. & Villard, E. Clin Genet (2023). 

Incidence, risk assessment and prevention of sudden cardiac death in cardiomyopathies. Polovina, M., Tschope, C., Rosano, G., Metra, M., Crea, F., Mullens, W., Bauersachs, J., Sliwa, K., de Boer, R. A., Farmakis, D., Thum, T., Corrado, D., Bayes Genis, A., Bozkurt, B., Filippatos, G., Keren, A., Skouri, H., Moura, B., Volterrani, M., Abdelhamid, M., Asanin, M., Krljanac, G., Tomic, M., Savarese, G., Adamo, M., Lopatin, Y., Chioncel, O., Coats, A. J. & Seferovic, P. M. Eur J Heart Fail (2023). 

Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors. Specker, E., Wesolowski, R., Schutz, A., Matthes, S., Mallow, K., Wasinska-Kalwa, M., Winkler, L., Oder, A., Alenina, N., Pleimes, D., von Kries, J. P., Heinemann, U., Bader, M. & Nazare, M. J Med Chem 66, 14866-14896 (2023).


Paper of the Month

Cell-intrinsic effects of clonal hematopoiesis in heart failure. DZHK-authors: Wesley T. Abplanalp, Sebastian Cremer, Maximilian Merten, Mariana Shumliakivska, Igor Macinkovic, Andreas M. Zeiher, David John & Stefanie Dimmeler. Nature Cardiovascular Researc. 2023.

A suspension of inactivated bacteria used for vaccination against recurrent urinary tract infections increases the phagocytic activity of murine macrophages. Eggers, A., Balluer, M., Mohamed, B. A., Nau, R. & Seele, J. Front Immunol 14, 1180785 (2023). 

The atypical antidepressant tianeptine confers neuroprotection against oxygen-glucose deprivation. Ersoy, B., Herzog, M. L., Pan, W., Schilling, S., Endres, M., Gottert, R., Kronenberg, G. D. & Gertz, K. Eur Arch Psychiatry Clin Neurosci (2023). 

Bifurcated Rhodaelectro-catalyzed C-H Activation for the Synthesis of Pyrroles and Lactones. Homolle, S. L., Stangier, M., Reyes, E. & Ackermann, L. Precis Chem 1, 382-387 (2023). 

Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation. Pekayvaz, K., Gold, C., Hoseinpour, P., Engel, A., Martinez-Navarro, A., Eivers, L., Coletti, R., Joppich, M., Dionisio, F., Kaiser, R., Tomas, L., Janjic, A., Knott, M., Mehari, F., Polewka, V., Kirschner, M., Boda, A., Nicolai, L., Schulz, H., Titova, A., Kilani, B., Lorenz, M., Fingerle-Rowson, G., Bucala, R., Enard, W., Zimmer, R., Weber, C., Libby, P., Schulz, C., Massberg, S. & Stark, K. Immunity (2023). 

Transcatheter aortic valve implantation versus surgical aortic valve replacement in patients at low to intermediate surgical risk: rationale and design of the randomised DEDICATE Trial. Seiffert, M., Vonthein, R., Baumgartner, H., Borger, M. A., Choi, Y. H., Falk, V., Frey, N., Hagendorff, A., Hagl, C., Hamm, C., Konig, I. R., Landmesser, U., Massberg, S., Reichenspurner, H., Thiele, H., Twerenbold, R., Vens, M., Walther, T., Ziegler, A., Cremer, J. & Blankenberg, S. EuroIntervention (2023). 

Comparison of Functional and Morphological Estimates of Vascular Age. Sigl, M., Winter, L., Schumacher, G., Helmke, S. C., Shchetynska-Marinova, T., Amendt, K., Duerschmied, D. & Hohneck, A. L. In Vivo 37, 2178-2187 (2023). 

The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis. Schoeler, M., Ellero-Simatos, S., Birkner, T., Mayneris-Perxachs, J., Olsson, L., Brolin, H., Loeber, U., Kraft, J. D., Polizzi, A., Marti-Navas, M., Puig, J., Moschetta, A., Montagner, A., Gourdy, P., Heymes, C., Guillou, H., Tremaroli, V., Fernandez-Real, J. M., Forslund, S. K., Burcelin, R. & Caesar, R. Nat Commun 14, 5329 (2023). 

The treatment of chronic anemia in heart failure: a global approach. Bianchi, V. E. & von Haehling, S. Clin Res Cardiol (2023). 

Associations between baseline heart rate and blood pressure and time to events in HFrEF patients: data from the QUALIFY international registry. Abdin, A., Anker, S. D., Cowie, M. R., Filippatos, G. S., Ponikowski, P., Tavazzi, L., Schope, J., Wagenpfeil, S., Komajda, M. & Bohm, M. Eur J Heart Fail (2023). 

Cell-intrinsic effects of clonal hematopoiesis in heart failure. Abplanalp, W. T., Schuhmacher, B., Cremer, S., Merten, M., Shumliakivska, M., Macinkovic, I., Zeiher, A. M., John, D. & Dimmeler, S. Nat Cardiovasc Res 2, 819-834 (2023). 

Jeanette Erdmann: 1965-2023. Aherrahrou, R., Martens, M., Regitz-Zagrosek, V. & Aherrahrou, Z. Eur Heart J (2023). 

REMIniscence of aldosterone's role in myocardial remodelling. Beer, B. N. & Schrage, B. Eur J Heart Fail (2023). 

Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers. Boen, R., Kaufmann, T., van der Meer, D., Frei, O., Agartz, I., Ames, D., Andersson, M., Armstrong, N. J., Artiges, E., Atkins, J. R., Bauer, J., Benedetti, F., Boomsma, D. I., Brodaty, H., Brosch, K., Buckner, R. L., Cairns, M. J., Calhoun, V., Caspers, S., Cichon, S., Corvin, A. P., Facorro, B. C., Dannlowski, U., David, F. S., de Geus, E. J. C., de Zubicaray, G. I., Desrivieres, S., Doherty, J. L., Donohoe, G., Ehrlich, S., Eising, E., Espeseth, T., Fisher, S. E., Forstner, A. J., Uya, L. F., Frouin, V., Fukunaga, M., Ge, T., Glahn, D. C., Goltermann, J., Grabe, H. J., Green, M. J., Groenewold, N. A., Grotegerd, D., Hahn, T., Hashimoto, R., Hehir-Kwa, J. Y., Henskens, F. A., Holmes, A. J., Haberg, A. K., Haavik, J., Jacquemont, S., Jansen, A., Jockwitz, C., Jonsson, E. G., Kikuchi, M., Kircher, T., Kumar, K., Le Hellard, S., Leu, C., Linden, D. E., Liu, J., Loughnan, R., Mather, K. A., McMahon, K. L., McRae, A. F., Medland, S. E., Meinert, S., Moreau, C. A., Morris, D. W., Mowry, B. J., Muhleisen, T. W., Nenadic, I., Nothen, M. M., Nyberg, L., Owen, M. J., Paolini, M., Paus, T., Pausova, Z., Persson, K., Quide, Y., Marques, T. R., Sachdev, P. S., Sando, S. B., Schall, U., Scott, R. J., Selbaek, G., Shumskaya, E., Silva, A. I., Sisodiya, S. M., Stein, F., Stein, D. J., Straube, B., Streit, F., Strike, L. T., Teumer, A., Teutenberg, L., Thalamuthu, A., Tooney, P. A., Tordesillas-Gutierrez, D., Trollor, J. N., Ent, D. V., van den Bree, M. B. M., van Haren, N. E. M., Vazquez-Bourgon, J., Volzke, H., Wen, W., Wittfeld, K., Ching, C. R. K., Westlye, L. T., Thompson, P. M., Bearden, C. E., Selmer, K. K., Alnaes, D., Andreassen, O. A. & Sonderby, I. E. Biol Psychiatry (2023). 

Contrast-enhanced cardiac MRI is superior to non-contrast mapping to predict left ventricular remodeling at 6 months after acute myocardial infarction. Chen, H., Erley, J., Muellerleile, K., Saering, D., Jahnke, C., Cavus, E., Schneider, J. N., Blankenberg, S., Lund, G. K., Adam, G., Tahir, E. & Sinn, M. Eur Radiol (2023). 

Highly accelerated free-breathing real-time 2D flow imaging using compressed sensing and shared velocity encoding. Xiong, F., Emrich, T., Schoepf, U. J., Jin, N., Hall, S., Ruddy, J. M., Giese, D., Lautenschlager, C., Emrich, A. L. & Varga-Szemes, A. Eur Radiol (2023). 

Diagnosis and outcomes of cachexia in Asia: Working Consensus Report from the Asian Working Group for Cachexia. Arai, H., Maeda, K., Wakabayashi, H., Naito, T., Konishi, M., Assantachai, P., Auyeung, W. T., Chalermsri, C., Chen, W., Chew, J., Chou, M. Y., Hsu, C. C., Hum, A., Hwang, I. G., Kaido, T., Kang, L., Kamaruzzaman, S. B., Kim, M., Lee, J. S. W., Lee, W. J., Liang, C. K., Lim, W. S., Lim, J. Y., Lim, Y. P., Lo, R. S., Ong, T., Pan, W. H., Peng, L. N., Pramyothin, P., Razalli, N. H., Saitoh, M., Shahar, S., Shi, H. P., Tung, H. H., Uezono, Y., von Haehling, S., Won, C. W., Woo, J. & Chen, L. K. J Cachexia Sarcopenia Muscle 14, 1949-1958 (2023). 

Coronary intravascular lithotripsy and rotational atherectomy for severely calcified stenosis: Results from the ROTA.shock trial. Blachutzik, F., Meier, S., Weissner, M., Schlattner, S., Gori, T., Ullrich, H., Gaede, L., Achenbach, S., Mollmann, H., Chitic, B., Aksoy, A., Nickenig, G., Weferling, M., Pons-Kuhnemann, J., Dorr, O., Boeder, N., Bayer, M., Elsasser, A., Hamm, C. W., Nef, H. & Investigators, R. O. s. Catheter Cardiovasc Interv (2023). 

Iron homeostasis in mice: does liver lobe matter? Colucci, S., Carvalho Oliveira, T., Muckenthaler, M. U. & Marques, O. Am J Physiol Gastrointest Liver Physiol 325, G453-G457 (2023). 

Correlation of systolic and diastolic blood pressure with echocardiographic phenotypes of cardiac structure and function from three German population-based studies. Nikorowitsch, J., Bei der Kellen, R., Haack, A., Magnussen, C., Prochaska, J., Wild, P. S., Dorr, M., Twerenbold, R., Schnabel, R. B., Kirchhof, P., Blankenberg, S., Markus, M. R. P. & Wenzel, J. P. Sci Rep 13, 14525 (2023). 

Beta-blockers and renin-angiotensin system inhibitors for Takotsubo syndrome recurrence: a network meta-analysis. Santoro, F., Sharkey, S., Citro, R., Miura, T., Arcari, L., Urbano-Moral, J. A., Stiermaier, T., Nunez-Gil, I. J., Silverio, A., Di Nunno, N., Ragnatela, I., Cetera, R., Nishida, J., Eitel, I. & Brunetti, N. D. Heart (2023). 

Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease. Amaya-Garrido, A., Brunet, M., Buffin-Meyer, B., Piedrafita, A., Grzesiak, L., Agbegbo, E., Del Bello, A., Ferrandiz, I., Ardeleanu, S., Bermudez-Lopez, M., Fedou, C., Camus, M., Burlet-Schiltz, O., Massines, J., Buleon, M., Feuillet, G., Alves, M., Neau, E., Casemayou, A., Breuil, B., Saulnier-Blache, J. S., Denis, C., Voelkl, J., Glorieux, G., Hobson, S., Arefin, S., Rahman, A., Kublickiene, K., Stenvinkel, P., Bascands, J. L., Faguer, S., Valdivielso, J. M., Schanstra, J. P. & Klein, J. Sci Transl Med 15, eabn5939 (2023). 

The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes. Giroud, M., Kotschi, S., Kwon, Y., Le Thuc, O., Hoffmann, A., Gil-Lozano, M., Karbiener, M., Higareda-Almaraz, J. C., Khani, S., Tews, D., Fischer-Posovszky, P., Sun, W., Dong, H., Ghosh, A., Wolfrum, C., Wabitsch, M., Virtanen, K. A., Bluher, M., Nielsen, S., Zeigerer, A., Garcia-Caceres, C., Scheideler, M., Herzig, S. & Bartelt, A. EMBO Rep 24, e57600 (2023). 

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ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1. Amin Sharifi, M., Wierer, M., An Dang, T., Milic, J., Moggio, A., Sachs, N., von Scheidt, M., Hinterdobler, J., Muller, P., Werner, J., Stiller, B., Aherrahrou, Z., Erdmann, J., Zaliani, A., Graettinger, M., Reinshagen, J., Gul, S., Gribbon, P., Maegdefessel, L., Bernhagen, J., Sager, H. B., Mann, M., Schunkert, H. & Kessler, T. Circ Res (2023). 

Completing the Cabrera Circle: deriving adaptable leads from ECG limb leads by combining constraints with a correction factor. Dathe, H., Krefting, D. & Spicher, N. Physiol Meas 44 (2023). 

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Comparison of balanced and unbalanced crystalloids as resuscitation fluid in patients treated for cardiogenic shock. Gmeiner, J., Bulach, B., Lusebrink, E., Binzenhofer, L., Kupka, D., Stocker, T., Low, K., Weckbach, L., Rudi, W. S., Petzold, T., Kaab, S., Hausleiter, J., Hagl, C., Massberg, S., Orban, M. & Scherer, C. J Intensive Care 11, 38 (2023). 

Sodium as an Important Regulator of Immunometabolism. Miyauchi, H., Geisberger, S., Luft, F. C., Wilck, N., Stegbauer, J., Wiig, H., Dechend, R., Jantsch, J., Kleinewietfeld, M., Kempa, S. & Muller, D. N. Hypertension (2023). 

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Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development. Seibertz, F., Rubio, T., Springer, R., Popp, F., Ritter, M., Liutkute, A., Bartelt, L., Stelzer, L., Haghighi, F., Pietras, J., Windel, H., Pedrosa, N. D. I., Rapedius, M., Doering, Y., Solano, R., Hindmarsh, R., Shi, R., Tiburcy, M., Bruegmann, T., Kutschka, I., Streckfuss-Bomeke, K., Kensah, G., Cyganek, L., Zimmermann, W. H. & Voigt, N. Cardiovasc Res 119, 2623-2637 (2023). 

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Use of the Wearable Cardioverter-Defibrillator Among Patients With Myocarditis and Reduced Ejection Fraction or Ventricular Tachyarrhythmia: Data From a Multicenter Registry. El-Battrawy, I., Koepsel, K., Tenbrink, D., Kovacs, B., Dreher, T. C., Blockhaus, C., Gotzmann, M., Klein, N., Kuntz, T., Shin, D. I., Lapp, H., Rosenkaimer, S., Abumayyaleh, M., Hamdani, N., Saguner, A. M., Kowitz, J., Erath, J. W., Duru, F., Mugge, A., Akin, I., Aweimer, A. & Beiert, T. J Am Heart Assoc 12, e030615 (2023). 

The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms. Fasolo, F., Winski, G., Li, Z., Wu, Z., Winter, H., Ritzer, J., Glukha, N., Roy, J., Hultgren, R., Pauli, J., Busch, A., Sachs, N., Knappich, C., Eckstein, H. H., Boon, R. A., Paloschi, V. & Maegdefessel, L. Mol Ther Nucleic Acids 33, 848-865 (2023). 

GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification. Lagou, V., Jiang, L., Ulrich, A., Zudina, L., Gonzalez, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Magi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, E., Epsilonvangelou, E., Benyamin, B., Scott, R. A., Isaacs, A., Zhao, J. H., Willems, S. M., Johnson, T., Gieger, C., Grallert, H., Meisinger, C., Muller-Nurasyid, M., Strawbridge, R. J., Goel, A., Rybin, D., Albrecht, E., Jackson, A. U., Stringham, H. M., Correa, I. R., Jr., Farber-Eger, E., Steinthorsdottir, V., Uitterlinden, A. G., Munroe, P. B., Brown, M. J., Schmidberger, J., Holmen, O., Thorand, B., Hveem, K., Wilsgaard, T., Mohlke, K. L., Wang, Z., Consortium, G.-P., Shmeliov, A., den Hoed, M., Loos, R. J. F., Kratzer, W., Haenle, M., Koenig, W., Boehm, B. O., Tan, T. M., Tomas, A., Salem, V., Barroso, I., Tuomilehto, J., Boehnke, M., Florez, J. C., Hamsten, A., Watkins, H., Njolstad, I., Wichmann, H. E., Caulfield, M. J., Khaw, K. T., van Duijn, C. M., Hofman, A., Wareham, N. J., Langenberg, C., Whitfield, J. B., Martin, N. G., Montgomery, G., Scapoli, C., Tzoulaki, I., Elliott, P., Thorsteinsdottir, U., Stefansson, K., Brittain, E. L., McCarthy, M. I., Froguel, P., Sexton, P. M., Wootten, D., Groop, L., Dupuis, J., Meigs, J. B., Deganutti, G., Demirkan, A., Pers, T. H., Reynolds, C. A., Aulchenko, Y. S., Kaakinen, M. A., Jones, B., Prokopenko, I., Meta-Analysis of, G. & Insulin-Related Traits, C. Nat Genet 55, 1448-1461 (2023). 

A simulation-based phantom model for generating synthetic mitral valve image data-application to MRI acquisition planning. Manini, C., Nemchyna, O., Akansel, S., Walczak, L., Tautz, L., Kolbitsch, C., Falk, V., Sundermann, S., Kuhne, T., Schulz-Menger, J. & Hennemuth, A. Int J Comput Assist Radiol Surg (2023). 

Increased blood pressure after nonsevere COVID-19. Schmidt-Lauber, C., Alba Schmidt, E., Hanzelmann, S., Petersen, E. L., Behrendt, C. A., Twerenbold, R., Blankenberg, S., Huber, T. B. & Wenzel, U. O. J Hypertens 41, 1721-1729 (2023). 

CD40L modulates CD4(+) T cell activation through receptor for activated C kinase 1. van Os, B. W., Vos, W. G., Bosmans, L. A., van Tiel, C. M., Toom, M. D., Beckers, L., Admiraal, M., Hoeksema, M. A., de Winther, M. P. & Lutgens, E. Eur J Immunol, e2350520 (2023). 

Cardiac iron metabolism during aging - Role of inflammation and proteolysis. Walter, S., Mertens, C., Muckenthaler, M. U. & Ott, C. Mech Ageing Dev 215, 111869 (2023). 

Epoxyeicosatrienoic Acids Prevent Cardiac Dysfunction in Viral Myocarditis via IFN-I Signaling. Zhou, Z., Zhang, M., Zhao, C., Gao, X., Wen, Z., Wu, J., Chen, C., Fleming, I., Hu, J. & Wang, D. W. Circ Res (2023). 

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High Thyroid-Stimulating Hormone and Low Free Triiodothyronine Levels Are Associated with Chronic Kidney Disease in Three Population-Based Studies from Germany. Ittermann, T., von Rheinbaben, S., Markus, M. R. P., Dorr, M., Steveling, A., Nauck, M., Teumer, A., Gollasch, M., Spira, D., Konig, M., Demuth, I., Steinhagen-Thiessen, E., Volzke, H. & Stracke, S. J Clin Med 12 (2023). 

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Treatment response to spironolactone in patients with heart failure with preserved ejection fraction: a machine learning-based analysis of two randomized controlled trials. Kresoja, K. P., Unterhuber, M., Wachter, R., Rommel, K. P., Besler, C., Shah, S., Thiele, H., Edelmann, F. & Lurz, P. EBioMedicine 96, 104795 (2023). 

The link between obesity and aging - insights into cardiac energy metabolism. Owesny, P. & Grune, T. Mech Ageing Dev 216, 111870 (2023). 

Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT(2) receptor ligands reveals that EMA401 and PD123319 have agonistic properties. Peluso, A. A., Souza-Silva, I. M., Villela, D. C., Hansen, P. B. L., Hallberg, A., Bader, M., Santos, R., Sumners, C. & Steckelings, U. M. Biochem Pharmacol 216, 115793 (2023). 

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Acute exposure to simulated nocturnal traffic noise and cardiovascular complications and sleep disturbance-results from a pooled analysis of human field studies. Hahad, O., Schmidt, F. P., Hubner, J., Foos, P., Al-Kindi, S., Schmitt, V. H., Hobohm, L., Keller, K., Grosse-Dresselhaus, C., Schmeisser, J., Koppe-Schmeisser, F., Vosseler, M., Gilan, D., Schulz, A., Chalabi, J., Wild, P. S., Daiber, A., Herzog, J. & Munzel, T. Clin Res Cardiol 112, 1690-1698 (2023). 

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Reticulated Platelets Predict Cardiovascular Death and Adverse Events in Coronary Artery Disease: A Systematic Review and Meta-analysis. Bongiovanni, D., Novelli, L., Condello, F., Kirmes, K., Han, J., Wein, B., Elvinger, S., Viggiani, G., von Scheidt, M., Laugwitz, K. L., Raake, P. W. J., Kastrati, A., Chiarito, M. & Bernlochner, I. Thromb Haemost (2023). 

Reusing Biomedical Data as Agreed - Towards Structured Metadata for Data Use Agreements. Bonisch, C., Hanss, S., Spicher, N., Sax, U. & Krefting, D. Stud Health Technol Inform 307, 31-38 (2023). 

Electroanatomical mapping after cardiac radioablation for treatment of incessant electrical storm: a case report from the RAVENTA trial. Kaestner, L., Boda-Heggemann, J., Fanslau, H., Xie, J., Schweikard, A., Giordano, F. A., Blanck, O. & Rudic, B. Strahlenther Onkol 199, 1018-1024 (2023). 

Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis. Kanwischer, L., Xu, X., Saifuddin, A. B., Maamari, S., Tan, X., Alnour, F., Tampe, B., Meyer, T., Zeisberg, M., Hasenfuss, G., Puls, M. & Zeisberg, E. M. Clin Epigenetics 15, 149 (2023). 

Author Correction: Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling. Pontarollo, G., Kollar, B., Mann, A., Khuu, M. P., Kiouptsi, K., Bayer, F., Brandao, I., Zinina, V. V., Hahlbrock, J., Malinarich, F., Mimmler, M., Bhushan, S., Marini, F., Ruf, W., Belheouane, M., Baines, J. F., Endres, K., Reba, S. M., Raker, V. K., Deppermann, C., Welsch, C., Bosmann, M., Soshnikova, N., Chassaing, B., Bergentall, M., Sommer, F., Backhed, F. & Reinhardt, C. Nat Metab (2023). 

Adaptability of Existing Feasibility Tools for Clinical Study Research Data Platforms. Witte, M. L., Schoneberg, A., Hanss, S., Lablans, M., Vehreschild, J. & Krefting, D. Stud Health Technol Inform 307, 39-48 (2023). 

The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis. Xu, Y., Derakhshan, A., Hysaj, O., Wildisen, L., Ittermann, T., Pingitore, A., Abolhassani, N., Medici, M., Kiemeney, L., Riksen, N. P., Dullaart, R. P. F., Trompet, S., Dorr, M., Brown, S. J., Schmidt, B., Fuhrer-Sakel, D., Vanderpump, M. P. J., Muendlein, A., Drexel, H., Fink, H. A., Ikram, M. K., Kavousi, M., Rhee, C. M., Bensenor, I. M., Azizi, F., Hankey, G. J., Iacoviello, M., Imaizumi, M., Ceresini, G., Ferrucci, L., Sgarbi, J. A., Bauer, D. C., Wareham, N., Boelaert, K., Bakker, S. J. L., Jukema, J. W., Vaes, B., Iervasi, G., Yeap, B. B., Westendorp, R. G. J., Korevaar, T. I. M., Volzke, H., Razvi, S., Gussekloo, J., Walsh, J. P., Cappola, A. R., Rodondi, N., Peeters, R. P., Chaker, L. & Thyroid Studies, C. Lancet Diabetes Endocrinol (2023). 

Impact of Clinical Study Implementation on Data Quality Assessments - Using Contradictions within Interdependent Health Data Items as a Pilot Indicator. Yusuf, K. O., Chaplinskaya-Sobol, I., Schoneberg, A., Hanss, S., Valentin, H., Lorenz-Depiereux, B., Hansch, S., Fiedler, K., Scherer, M., Sikdar, S., Miljukov, O., Reese, J. P., Wagner, P., Brohl, I., Geisler, R., Vehreschild, J. J., Blaschke, S., Bellinghausen, C., Milovanovic, M. & Krefting, D. Stud Health Technol Inform 307, 152-158 (2023). 

Supervised exercise training in patients with advanced heart failure and left ventricular assist device: A multicentre randomized controlled trial (Ex-VAD trial). Feuerstein, A., Schoenrath, F., Belyavskiy, E., Knierim, J., Friede, T., Placzek, M., Bach, D., Pieske-Kraigher, E., Herrmann-Lingen, C., Westenfeld, R., Roden, M., Rybczynski, M., Verheyen, N., Dorr, M., von Haehling, S., Stork, S., Halle, M., Falk, V., Pieske, B. & Edelmann, F. Eur J Heart Fail (2023). 

Membrane-bound Interleukin-1alpha mediates leukocyte adhesion during atherogenesis. Maeder, C., Speer, T., Wirth, A., Boeckel, J. N., Fatima, S., Shahzad, K., Freichel, M., Laufs, U. & Gaul, S. Front Immunol 14, 1252384 (2023). 

A Fecal Metabolite Signature of Impaired Fasting Glucose: Results From Two Independent Population-Based Cohorts. Nogal, A., Tettamanzi, F., Dong, Q., Louca, P., Visconti, A., Christiansen, C., Breuninger, T., Linseisen, J., Grallert, H., Wawro, N., Asnicar, F., Wong, K., Baleanu, A. F., Michelotti, G. A., Segata, N., Falchi, M., Peters, A., Franks, P. W., Bagnardi, V., Spector, T. D., Bell, J. T., Gieger, C., Valdes, A. M. & Menni, C. Diabetes 72, 1870-1880 (2023). 

Rapid MR elastography of the liver for subsecond stiffness sampling. Anders, M., Meyer, T., Warmuth, C., Pfeuffer, J., Tzschaetzsch, H., Herthum, H., Shahryari, M., Degenhardt, K., Wieben, O., Schmitter, S., Schulz-Menger, J., Schaeffter, T., Braun, J. & Sack, I. Magn Reson Med 91, 312-324 (2024). 

Computational tools for inferring transcription factor activity. Hecker, D., Lauber, M., Behjati Ardakani, F., Ashrafiyan, S., Manz, Q., Kersting, J., Hoffmann, M., Schulz, M. H. & List, M. Proteomics, e2200462 (2023). 

Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease. Baidildinova, G., Pallares Robles, A., Ten Cate, V., Kremers, B. M. M., Heitmeier, S., Ten Cate, H., Mees, B. M. E., Spronk, H. M. H., Wild, P. S., Ten Cate-Hoek, A. J. & Jurk, K. Thromb Res 230, 105-118 (2023). 

Chemoselective Methods for Labeling and Modification of Peptides and Proteins. Brimble, M. A., Ackermann, L., Li, Y. M. & Raj, M. Org Lett 25, 6605-6606 (2023). 

Cardiorenal Outcomes with Finerenone in Asian Patients with Chronic Kidney Disease and Type 2 Diabetes: A FIDELIO-DKD post hoc Analysis. Koya, D., Anker, S. D., Ruilope, L. M., Rossing, P., Liu, Z., Lee, B. W., Lee, C. T., Scott, C., Kolkhof, P., Lawatscheck, R., Wang, L., Joseph, A., Pitt, B. & Investigators, F.-D. Am J Nephrol, 1-9 (2023). 

Outcomes of patients with atrial fibrillation on oral anticoagulation with and without heart failure: the ETNA-AF-Europe registry. Schnabel, R. B., Ameri, P., Siller-Matula, J. M., Diemberger, I., Gwechenberger, M., Pecen, L., Manu, M. C., Souza, J., De Caterina, R. & Kirchhof, P. Europace (2023). 

Safety, accuracy, and prediction of prognosis in patients with end-stage chronic kidney disease undergoing dobutamine stress cardiac magnetic resonance imaging. Weberling, L. D., Seitz, S., Salatzki, J., Ochs, A., Haney, A. C., Siry, D., Heins, J., Steen, H., Frey, N. & Andre, F. Front Cardiovasc Med 10, 1228691 (2023). 

QRS complex and T wave planarity for the efficacy prediction of automatic implantable defibrillators. Hnatkova, K., Andrsova, I., Novotny, T., Vanderberk, B., Sprenkeler, D., Junttila, J., Reichlin, T., Schlogl, S., Vos, M. A., Friede, T., Bauer, A., Huikuri, H. V., Willems, R., Schmidt, G., Sticherling, C., Zabel, M. & Malik, M. Heart (2023). 

Associations of circulating GDF15 with combined cognitive frailty and depression in older adults of the MARK-AGE study. Kochlik, B., Herpich, C., Moreno-Villanueva, M., Klaus, S., Muller-Werdan, U., Weinberger, B., Fiegl, S., Toussaint, O., Debacq-Chainiaux, F., Schon, C., Bernhard, J., Breusing, N., Gonos, E. S., Franceschi, C., Capri, M., Sikora, E., Hervonen, A., Hurme, M., Slagboom, P. E., Dolle, M. E. T., Jansen, E., Grune, T., Burkle, A. & Norman, K. Geroscience (2023). 

The contribution of the AT1 receptor to erythropoiesis. Rodrigues, A. F. & Bader, M. Biochem Pharmacol 217, 115805 (2023). 

Alpha-1 antitrypsin (AAT) augmentation and the liver phenotype of adults with AAT deficiency (genotype Pi*ZZ). Fromme, M., Hamesch, K., Schneider, C. V., Mandorfer, M., Pons, M., Thorhauge, K., Pereira, V., Sperl, J., Frankova, S., Reichert, M. C., Benini, F., Burbaum, B., Kleinjans, M., Amzou, S., Rademacher, L., Bewersdorf, L., Verbeek, J., Nevens, F., Genesca, J., Miravitlles, M., Nunez, A., Schaefer, B., Zoller, H., Janciauskiene, S., Waern, J., Oliveira, A., Maia, L., Simoes, C., Mahadeva, R., Fraughen, D. D., Trauner, M., Krag, A., Lammert, F., Bals, R., Gaisa, N. T., Aigner, E., Griffiths, W. J., Denk, H., Teumer, A., McElvaney, N. G., Turner, A. M., Trautwein, C. & Strnad, P. Clin Gastroenterol Hepatol (2023). 

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A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions. Fonseca, C. G., Silverio, V., Barata, D., Giese, W., Gerhardt, H., Cardoso, S. & Franco, C. A. Microsyst Nanoeng 9, 114 (2023). 

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Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy. He, H., Fasoula, N. A., Karlas, A., Omar, M., Aguirre, J., Lutz, J., Kallmayer, M., Fuchtenbusch, M., Eckstein, H. H., Ziegler, A. & Ntziachristos, V. Light Sci Appl 12, 231 (2023). 

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Outcomes After Transcatheter Mitral Valve Replacement According to Regurgitation Etiology. Perrin, N., Ben Ali, W., Ludwig, S., Duncan, A., Weimann, J., Nickenig, G., Tanaka, T., Coisne, A., Vincentelli, A., Makkar, R., Webb, J. G., Akodad, M., Muller, D. W. M., Jansz, P., Praz, F., Reineke, D., Wild, M. G., Hausleiter, J., Goel, S. S., Denti, P., Chehab, O., Dahle, G., Baldus, S., Ruge, H., Kaneko, T., Ternacle, J., Dumonteil, N., Stephan von Bardeleben, R., Flagiello, M., Walther, T., Taramasso, M., Sondergaard, L., Bleiziffer, S., Fam, N., Kempfert, J., Granada, J. F., Tang, G. H. L., Conradi, L., Modine, T. & Investigators, C.-M. Ann Thorac Surg (2023). 

Diseases of the Coronary Microcirculation: Diagnosis and Treatment. Ullrich-Daub, H., Daub, S., Olschewski, M., Munzel, T. & Gori, T. Dtsch Arztebl Int 120, 739-746 (2023). 

Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease. Benedek, T., Wieske, V., Szilveszter, B., Kofoed, K. F., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Veselka, J., Sakalyte, G., Adic, N. C., Gutberlet, M., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M., Ilnicka-Suckiel, M., Plank, F., Knuuti, J., Faria, R., Schroder, S., Berry, C., Saba, L., Ruzsics, B., Rieckmann, N., Kubiak, C., Schultz Hansen, K., Muller-Nordhorn, J., Merkely, B., Sigvardsen, P. E., Benedek, I., Orr, C., Valente, F. X., Zvaigzne, L., Horvath, M., Jankauskas, A., Adic, F., Woinke, M., Mulvihill, N., Lecumberri, I., Thwaite, E., Laule, M., Kruk, M., Stefanovic, M., Mancone, M., Kusmierz, D., Feuchtner, G., Pietila, M., Ribeiro, V. G., Drosch, T., Delles, C., Melis, M., Fisher, M., Boussoussou, M., Kragelund, C., Aurelian, R., Kelly, S., Garcia Del Blanco, B., Rubio, A., Karolyi, M., Hove, J. D., Rodean, I., Regan, S., Calabria, H. C., Geller, L., Larsen, L., Hodas, R., Napp, A. E., Haase, R., Feger, S., Mohamed, M., Serna-Higuita, L. M., Neumann, K., Dreger, H., Rief, M., Danesh, J., Estrella, M., Bosserdt, M., Martus, P., Dodd, J. D. & Dewey, M. Diabetes Care 46, 2015-2023 (2023). 

Driveline infections in left ventricular assist devices-Incidence, epidemiology, and staging proposal. Dettbarn, E., Prenga, M., Stein, J., Muller, M., Hoermandinger, C., Schoenrath, F., Falk, V., Potapov, E., Mulzer, J. & Knierim, J. Artif Organs (2023). 

Editorial: Advances in cAMP signaling research: basic and translational aspects. Aslam, M. & Ladilov, Y. Front Physiol 14, 1266718 (2023). 

Repurposing the beta3-Adrenergic Receptor Agonist Mirabegron in Patients With Structural Cardiac Disease: The Beta3-LVH Phase 2b Randomized Clinical Trial. Balligand, J. L., Brito, D., Brosteanu, O., Casadei, B., Depoix, C., Edelmann, F., Ferreira, V., Filippatos, G., Gerber, B., Gruson, D., Hasenclever, D., Hellenkamp, K., Ikonomidis, I., Krakowiak, B., Lhommel, R., Mahmod, M., Neubauer, S., Persu, A., Piechnik, S., Pieske, B., Pieske-Kraigher, E., Pinto, F., Ponikowski, P., Senni, M., Trochu, J. N., Van Overstraeten, N., Wachter, R. & Pouleur, A. C. JAMA Cardiol (2023). 

Mitigating Radiotoxicity in the Central Nervous System: Role of Proton Therapy. Winter, S. F., Vaios, E. J., Shih, H. A., Grassberger, C., Parsons, M. W., Gardner, M. M., Ehret, F., Kaul, D., Boehmerle, W., Endres, M. & Dietrich, J. Curr Treat Options Oncol (2023). 

Calcium channel beta3 subunit regulates ATP-dependent migration of dendritic cells. Woo, M. S., Ufer, F., Sonner, J. K., Belkacemi, A., Tintelnot, J., Saez, P. J., Krieg, P. F., Mayer, C., Binkle-Ladisch, L., Engler, J. B., Bauer, S., Kursawe, N., Vieira, V., Mannebach, S., Freichel, M., Flockerzi, V., Vargas, P. & Friese, M. A. Sci Adv 9, eadh1653 (2023). 

Correction: Catalytic antibodies in arrhythmogenic cardiomyopathy patients cleave desmoglein 2 and N-cadherin and impair cardiomyocyte cohesion. Yeruva, S., Stangner, K., Jungwirth, A., Hiermaier, M., Shoykhet, M., Kugelmann, D., Hertl, M., Egami, S., Ishii, N., Koga, H., Hashimoto, T., Weis, M., Beckmann, B. M., Biller, R., Schuttler, D., Kaab, S. & Waschke, J. Cell Mol Life Sci 80, 296 (2023). 

Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide. Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S. K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J. E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M. T., Hoyles, L., Alves, R., Helft, G., Isnard, R., Kober, L., Coelho, L. P., Rouault, C., Gauguier, D., Gotze, J. P., Prifti, E., Froguel, P., MetaCardis, C., Zucker, J. D., Backhed, F., Vestergaard, H., Hansen, T., Oppert, J. M., Bluher, M., Nielsen, J., Raes, J., Bork, P., Yaqoob, M. M., Stumvoll, M., Pedersen, O., Ehrlich, S. D., Clement, K. & Dumas, M. E. Nat Commun 14, 5843 (2023). 

Arrhythmogenic Cardiomyopathy: from Preclinical Models to Genotype-phenotype Correlation and Pathophysiology. Fan, X., Yang, G., Duru, F., Grilli, M., Akin, I., Zhou, X., Saguner, A. M. & Ei-Battrawy, I. Stem Cell Rev Rep (2023). 

Tricuspid Regurgitation: From Imaging to Clinical Trials to Resolving the Unmet Need for Treatment. Grapsa, J., Praz, F., Sorajja, P., Cavalcante, J. L., Sitges, M., Taramasso, M., Piazza, N., Messika-Zeitoun, D., Michelena, H. I., Hamid, N., Dreyfus, J., Benfari, G., Argulian, E., Chieffo, A., Tchetche, D., Rudski, L., Bax, J. J., Stephan von Bardeleben, R., Patterson, T., Redwood, S., Bapat, V. N., Nickenig, G., Lurz, P., Hausleiter, J., Kodali, S., Hahn, R. T., Maisano, F. & Enriquez-Sarano, M. JACC Cardiovasc Imaging 17, 79-95 (2024). 

5-Aminovaleric acid betaine predicts impaired glucose metabolism and diabetes. Haberbosch, L., Kierszniowska, S., Willmitzer, L., Mai, K., Spranger, J. & Maurer, L. Nutr Diabetes 13, 17 (2023). 

Expanding Success of Mitral Transcatheter Edge-to-Edge Repair in Real-World Patients: And More Questions to Answer. Orban, M. & Hausleiter, J. J Am Coll Cardiol 82, 1298-1300 (2023). 

Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of Staphylococcus aureus. Weiss, S., Holtfreter, S., Meyer, T. C., Schmiedeke, F., Cammann, C., Dorr, M., Felix, S. B., Grabe, H. J., Homuth, G., Kohler, C., Mahncke, C., Michalik, S., Nauck, M., Friedrich, N., Samietz, S., Volzke, H., Volker, U. & Broker, B. M. Front Immunol 14, 1229562 (2023). 

New opportunities for bioresorbable scaffold technology. Kastrati, A. & Seguchi, M. AsiaIntervention 9, 103-104 (2023). 

Ruthenium-Catalyzed Aminocarbonylation with Isocyanates Through Weak Coordinating Groups. Lai, E. Y., Yuan, B., Ackermann, L. & Johansson, M. J. Chemistry 29, e202302023 (2023). 

Spatiotemporal, optogenetic control of gene expression in organoids. Legnini, I., Emmenegger, L., Zappulo, A., Rybak-Wolf, A., Wurmus, R., Martinez, A. O., Jara, C. C., Boltengagen, A., Hessler, T., Mastrobuoni, G., Kempa, S., Zinzen, R., Woehler, A. & Rajewsky, N. Nat Methods (2023). 

Corrigendum to "Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study" [Sci. Total Environ. 900 (2023) 165780]. Yao, Y., Schneider, A., Wolf, K., Zhang, S., Wang-Sattler, R., Prehn, C., Adamski, J., Peters, A. & Breitner, S. Sci Total Environ 905, 167050 (2023). 

Clinical characteristics and prognosis of patients with heart failure and high concentrations of interleukin-17D. Baumhove, L., Bomer, N., Tromp, J., van Essen, B. J., Dickstein, K., Cleland, J. G., Lang, C. C., Ng, L. L., Samani, N. J., Anker, S. D., Metra, M., van Veldhuisen, D. J., van der Meer, P. & Voors, A. A. Int J Cardiol, 131384 (2023). 

Endothelial damage inhibitor preserves the integrity of venous endothelial cells from patients undergoing coronary bypass surgery. Nazari-Shafti, T. Z., Thau, H., Zacharova, E., Beez, C. M., Exarchos, V., Neuber, S., Meyborg, H., Puhl, K., Wittig, C., Szulcek, R., Neumann, K., Giampietro, C., Kruger, K., Cesarovic, N., Falk, V., Caliskan, E., Rodriguez Cetina Biefer, H. & Emmert, M. Y. Eur J Cardiothorac Surg 64 (2023). 

Association of cumulative remnant cholesterol with incident adverse cardiovascular events in the elderly: another piece in the puzzle. Klingenberg, R. Eur J Prev Cardiol 30, 1922-1923 (2023). 

Tankyrase inhibition interferes with junction remodeling, induces leakiness, and disturbs YAP1/TAZ signaling in the endothelium. Ma, N., Wibowo, Y. C., Wirtz, P., Baltus, D., Wieland, T. & Jansen, S. Naunyn Schmiedebergs Arch Pharmacol (2023). 

Bivalirudin Versus Heparin During PCI in NSTEMI: Individual Patient Data Meta-Analysis of Large Randomized Trials. Bikdeli, B., Erlinge, D., Valgimigli, M., Kastrati, A., Han, Y., Steg, P. G., Stables, R. H., Mehran, R., James, S. K., Frigoli, E., Goldstein, P., Li, Y., Shahzad, A., Schupke, S., Mehdipoor, G., Chen, S., Redfors, B., Crowley, A., Zhou, Z. & Stone, G. W. Circulation (2023). 

Transvenous lead extraction in children with bidirectional rotational dissection sheaths. Heck, R., Peters, B., Lanmuller, P., Photiadis, J., Berger, F., Falk, V., Starck, C. & Kramer, P. Front Cardiovasc Med 10, 1256752 (2023). 

Prediction of Stroke Outcome in Mice Based on Noninvasive MRI and Behavioral Testing. Knab, F., Koch, S. P., Major, S., Farr, T. D., Mueller, S., Euskirchen, P., Eggers, M., Kuffner, M. T. C., Walter, J., Berchtold, D., Knauss, S., Dreier, J. P., Meisel, A., Endres, M., Dirnagl, U., Wenger, N., Hoffmann, C. J., Boehm-Sturm, P. & Harms, C. Stroke 54, 2895-2905 (2023). 

Comparison of procedural characteristics of percutaneous annuloplasty and edge-to-edge repair for the treatment of severe tricuspid regurgitation. Mattig, I., Barbieri, F., Kasner, M., Romero Dorta, E., Heinrich-Schuler, A. L., Zhu, M., Stangl, K., Landmesser, U., Reinthaler, M. & Dreger, H. Front Cardiovasc Med 10, 1232327 (2023). 

Procedural outcome & risk prediction in young patients undergoing transvenous lead extraction-a GALLERY subgroup analysis. Rexha, E., Chung, D. U., Burger, H., Ghaffari, N., Madej, T., Ziaukas, V., Hassan, K., Reichenspurner, H., Gessler, N., Willems, S., Butter, C., Pecha, S. & Hakmi, S. Front Cardiovasc Med 10, 1251055 (2023). 

Finerenone in Hispanic Patients With CKD and Type 2 Diabetes: A Post Hoc FIDELITY Analysis. Rosas, S. E., Ruilope, L. M., Anker, S. D., Pitt, B., Rossing, P., Bonfanti, A. A. C., Correa-Rotter, R., Gonzalez, F., Munoz, C. F. J., Pergola, P., Umpierrez, G. E., Scalise, A., Scott, C., Lawatscheck, R., Joseph, A., Bakris, G. L., Fidelio, D. K. D. & investigators, F.-D. Kidney Med 5, 100704 (2023). 

Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charite Fatigue Center. Steiner, S., Fehrer, A., Hoheisel, F., Schoening, S., Aschenbrenner, A., Babel, N., Bellmann-Strobl, J., Finke, C., Fluge, O., Froehlich, L., Goebel, A., Grande, B., Haas, J. P., Hohberger, B., Jason, L. A., Komaroff, A. L., Lacerda, E., Liebl, M., Maier, A., Mella, O., Nacul, L., Paul, F., Prusty, B. K., Puta, C., Riemekasten, G., Ries, W., Rowe, P. C., Sawitzki, B., Shoenfeld, Y., Schultze, J. L., Seifert, M., Sepulveda, N., Sotzny, F., Stein, E., Stingl, M., Ufer, F., Veauthier, C., Westermeier, F., Wirth, K., Wolfarth, B., Zalewski, P., Behrends, U. & Scheibenbogen, C. Autoimmun Rev 22, 103452 (2023). 

Strong association of depression and anxiety with the presence of back pain while impact of spinal imaging findings is limited: analysis of an MRI cohort study. Stoecklein, V. M., Grosu, S., Nikolova, T., Tonn, J. C., Zausinger, S., Ricke, J., Schlett, C. L., Maurer, E., Walter, S. S., Peters, A., Bamberg, F., Rospleszcz, S. & Stoecklein, S. J Pain (2023). 

Development and Phenotype of Heart Failure in Long-Term Survivors of Childhood Cancer: The CVSS Study. Gobel, S., Wingerter, A., Prochaska, J. H., Schulz, A., Neu, M. A., Henninger, N., Spix, C., Beutel, M., Lackner, K., Munzel, T., Lam, C. S., Merzenich, H., Faber, J. & Wild, P. S. J Am Heart Assoc 12, e030020 (2023). 

Publisher Correction: Acute exposure to simulated nocturnal traffic noise and cardiovascular complications and sleep disturbance-results from a pooled analysis of human field studies. Hahad, O., Schmidt, F. P., Hubner, J., Foos, P., Al-Kindi, S., Schmitt, V. H., Hobohm, L., Keller, K., Grosse-Dresselhaus, C., Schmeisser, J., Koppe-Schmeisser, F., Vosseler, M., Gilan, D., Schulz, A., Chalabi, J., Wild, P. S., Daiber, A., Herzog, J. & Munzel, T. Clin Res Cardiol (2023). 

Kinins: Locally formed peptides during inflammation with potential use in tissue regeneration. Martins, L., Bader, M. & Pesquero, J. B. Inflamm Res 72, 1957-1963 (2023). 

Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia. Taylor, J., Uhl, L., Moll, I., Hasan, S. S., Wiedmann, L., Morgenstern, J., Giaimo, B. D., Friedrich, T., Alsina-Sanchis, E., De Angelis Rigotti, F., Mulfarth, R., Kaltenbach, S., Schenk, D., Nickel, F., Fleming, T., Sprinzak, D., Mogler, C., Korff, T., Billeter, A. T., Muller-Stich, B. P., Berriel Diaz, M., Borggrefe, T., Herzig, S., Rohm, M., Rodriguez-Vita, J. & Fischer, A. Nat Cancer (2023). 

Genetic dissection of serum vaspin highlights its causal role in lipid metabolism. Breitfeld, J., Horn, K., Le Duc, D., Velluva, A., Marzi, C., Grallert, H., Friedrich, N., Pietzner, M., Volker, U., Volzke, H., Ahlqvist, E., Aly, D. M., Tuomi, T., Baber, R., Kratzsch, J., Thiery, J., Isermann, B., Loeffler, M., Kloting, N., Bluher, M., Stumvoll, M., Heiker, J. T., Tonjes, A., Scholz, M. & Kovacs, P. Obesity (Silver Spring) 31, 2862-2874 (2023). 

Clinical and Translational Imaging and Sensing of Diabetic Microangiopathy: A Narrative Review. Fasoula, N. A., Xie, Y., Katsouli, N., Reidl, M., Kallmayer, M. A., Eckstein, H. H., Ntziachristos, V., Hadjileontiadis, L., Avgerinos, D. V., Briasoulis, A., Siasos, G., Hosseini, K., Doulamis, I., Kampaktsis, P. N. & Karlas, A. J Cardiovasc Dev Dis 10 (2023). 

Prevalence, one-year-incidence and predictors of carcinoid heart disease. Mattig, I., Franke, M. R., Pschowski, R., Brand, A., Stangl, K., Knebel, F. & Dreger, H. Cardiovasc Ultrasound 21, 18 (2023). 

Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFbeta1 and IL-27. Riehl, D. R., Sharma, A., Roewe, J., Murke, F., Ruppert, C., Eming, S. A., Bopp, T., Kleinert, H., Radsak, M. P., Colucci, G., Subramaniam, S., Reinhardt, C., Giebel, B., Prinz, I., Guenther, A., Strand, D., Gunzer, M., Waisman, A., Ward, P. A., Ruf, W., Schafer, K. & Bosmann, M. Proc Natl Acad Sci U S A 120, e2215421120 (2023). 

Recurrent Events in Cardiovascular Trials: JACC State-of-the-Art Review. Gregson, J., Stone, G. W., Bhatt, D. L., Packer, M., Anker, S. D., Zeller, C., Redfors, B. & Pocock, S. J. J Am Coll Cardiol 82, 1445-1463 (2023). 

Differential Effects of the Betablockers Carvedilol, Metoprolol and Bisoprolol on Cardiac K(v)4.3 (I(to)) Channel Isoforms. Rahm, A. K., Hackbarth, J., Muller, M. E., Pfeiffer, J., Gampp, H., Petersenn, F., Rivinius, R., Frey, N., Lugenbiel, P. & Thomas, D. Int J Mol Sci 24 (2023). 

Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction. Sayour, N. V., Toth, V. E., Nagy, R. N., Voros, I., Gergely, T. G., Onodi, Z., Nagy, N., Bodor, C., Varadi, B., Ruppert, M., Radovits, T., Bleckwedel, F., Zelarayan, L. C., Pacher, P., Agg, B., Gorbe, A., Ferdinandy, P. & Varga, Z. V. Int J Mol Sci 24 (2023). 

Cardiac Troponin I but Not N-Terminal Pro-B-Type Natriuretic Peptide Predicts Outcomes in Cardiogenic Shock. Schupp, T., Rusnak, J., Forner, J., Weidner, K., Ruka, M., Egner-Walter, S., Dudda, J., Bertsch, T., Kittel, M., Behnes, M. & Akin, I. J Pers Med 13 (2023). 

Flagellin-Induced Immune Response in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Yuecel, G., Zhou, X., Terkatz, L., Wendel, A., Reinhardt, J., El-Battrawy, I., Sattler, K., Cyganek, L., Utikal, J., Langer, H., Scharf, R., Duerschmied, D. & Akin, I. Int J Mol Sci 24 (2023). 

Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing. Cui, L., Yang, B., Xiao, S., Gao, J., Baud, A., Graham, D., McBride, M., Dominiczak, A., Schafer, S., Aumatell, R. L., Mont, C., Teruel, A. F., Hubner, N., Flint, J., Mott, R. & Huang, L. Genome Biol 24, 215 (2023). 

4D-Printable Photocrosslinkable Polyurethane-Based Inks for Tissue Scaffold and Actuator Applications. Goodarzi Hosseinabadi, H., Biswas, A., Bhusal, A., Yousefinejad, A., Lall, A., Zimmermann, W. H., Miri, A. K. & Ionov, L. Small, e2306387 (2023). 

Do we practice what we preach? Implementation of cardiovascular prevention strategies in 13 European countries between 2011 and 2021. A statement of the European Association of Preventive Cardiology of the ESC. Krankel, N., Scherrenberg, M., Abela, M., Shemesh, E., Kopylova, O., Babu, A. S., Gaber, M. H., Sliz, D. & Salzwedel, A. Eur J Prev Cardiol (2023). 

Instructions for use: when and how to glue the dissected aorta. Montagner, M., Kofler, M., Falk, V. & Kempfert, J. Eur J Cardiothorac Surg 64 (2023). 

Height, Autoimmune Thyroid Disease, and Thyroid Cancer: A Mendelian Randomization Study. Papadopoulou, A., Asvold, B. O., Burgess, S., Kus, A., Medici, M., Sterenborg, R., Teumer, A., Deloukas, P. & Marouli, E. Thyroid 33, 1476-1482 (2023). 

Impact of different in vitro models on functional performance of the self-expanding transcatheter heart valve. Sadat, N., Lojenburg, J. H., Scharfschwerdt, M., Fujta, B. & Ensminger, S. Eur J Cardiothorac Surg 64 (2023). 

Implementation of Recommendations for Features and Measurements of Experimental Acute Lung Injury. Setiawan, D. C. B., Simmons, S., Michalick, L. & Kuebler, W. M. Am J Respir Cell Mol Biol 69, 484-487 (2023).


Paper of the Month

Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. DZHK-authors: Christine Magnussen, Marcus Dörr, Anette Peters, Raphael Twerenbold, Philipp S. Wild, Andreas Ziegler, Stefan Blankenberg, Wolfgang König, Karl J. Lackner, David M. Leistner, Thiess Lorenz, Julia Waibel. New England Journal of Medicine. 2023.

Evaluation of right-ventricular function by two-dimensional echocardiography and two-dimensional speckle-tracking echocardiography in patients with successful RCA CTO recanalization. Blessing, R., Drosos, I., Molitor, M., Munzel, T., Wenzel, P., Gori, T. & Dimitriadis, Z. Clin Res Cardiol 112, 1454-1462 (2023). 

The infrastructure of electrophysiology centers impacts the management of cardiac tamponade-Results from a national survey. Rottner, L., Reubold, S., Schonhofer, S., Reissmann, B., Ouyang, F., Obergassel, J., My, I., Moser, F., Wenzel, J. P., Lemoine, M., Steven, D., Sommer, P., Kirchhof, P., Rillig, A. & Metzner, A. Clin Cardiol 46, 1210-1219 (2023). 

G-protein-coupled receptor MAS deletion produces a preeclampsia-like phenotype in FVB/N mice. Vieira Pimentel, R. L., Braga, J. F., Velloso, E. P. P., Lautner, R. Q., de Oliveira, M. L., Todiras, M., Alenina, N., Bader, M., de Sousa, F. G., Beier, S. L. & Santos, R. Clin Sci (Lond) 137, 1249-1263 (2023). 

Estimates of protection levels against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season: the IMMUNEBRIDGE project. Lange, B., Jaeger, V. K., Harries, M., Rucker, V., Streeck, H., Blaschke, S., Petersmann, A., Toepfner, N., Nauck, M., Hassenstein, M. J., Dreier, M., von Holt, I., Budde, A., Bartz, A., Ortmann, J., Kurosinski, M. A., Berner, R., Borsche, M., Brandhorst, G., Brinkmann, M., Budde, K., Deckena, M., Engels, G., Fenzlaff, M., Hartel, C., Hovardovska, O., Katalinic, A., Kehl, K., Kohls, M., Kruger, S., Lieb, W., Meyer-Schlinkmann, K. M., Pischon, T., Rosenkranz, D., Rubsamen, N., Rupp, J., Schafer, C., Schattschneider, M., Schlegtendal, A., Schlinkert, S., Schmidbauer, L., Schulze-Wundling, K., Stork, S., Tiemann, C., Volzke, H., Winter, T., Klein, C., Liese, J., Brinkmann, F., Ottensmeyer, P. F., Reese, J. P., Heuschmann, P. & Karch, A. Infection (2023). 

Datawarehouse-enabled quality control of atrial fibrillation detection in the stroke unit setting. Andina, M. E., Nelde, A., Nolte, C. H., Scheitz, J. F., Olma, M. C., Kramer, M., Meisel, E., Bingel, A., Meisel, A., Scheibe, F., Endres, M., Schlemm, L. & Meisel, C. Heliyon 9, e18432 (2023). 

Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The CAMEO-DAPA Trial. Borlaug, B. A., Reddy, Y. N. V., Braun, A., Sorimachi, H., Omar, M., Popovic, D., Alogna, A., Jensen, M. D. & Carter, R. Circulation (2023). 

Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome. Chowdhury, A., Boshnakovska, A., Aich, A., Methi, A., Vergel Leon, A. M., Silbern, I., Luchtenborg, C., Cyganek, L., Prochazka, J., Sedlacek, R., Lindovsky, J., Wachs, D., Nichtova, Z., Zudova, D., Koubkova, G., Fischer, A., Urlaub, H., Brugger, B., Katschinski, D. M., Dudek, J. & Rehling, P. EMBO Mol Med 15, e17399 (2023). 

Pulsed Field Ablation-Based Pulmonary Vein Isolation Using a Simplified Single-Access Single-Catheter Approach - The Fast and Furious PFA Study. Tilz, R. R., Vogler, J., Kirstein, B., Eitel, C., Phan, H. L., Popescu, S. S., Hatahet, S., Grosse, N., Subin, B., Lopez, L. D., Kuck, K. H. & Heeger, C. H. Circ J (2023). 

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Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy. Alenazy, F. O., Harbi, M. H., Kavanagh, D. P., Price, J., Brady, P., Hargreaves, O., Harrison, P., Slater, A., Tiwari, A., Nicolson, P. L. R., Connolly, D. L., Kirchhof, P., Kalia, N., Jandrot-Perrus, M., Mangin, P. H., Watson, S. P. & Thomas, M. R. J Thromb Haemost 21, 3236-3251 (2023). 

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Short-Term Western Diet Causes Rapid and Lasting Alterations of Bone Marrow Physiology. Bianchini, M., Moller-Ramon, Z., Weber, C., Megens, R. T. A. & Duchene, J. Thromb Haemost 123, 1100-1104 (2023). 

Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. Ni, W., Breitner, S., Nikolaou, N., Wolf, K., Zhang, S., Peters, A., Herder, C. & Schneider, A. Environ Sci Technol 57, 12210-12221 (2023). 

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Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism. Alfaro, A. J., Dittner, C., Becker, J., Loft, A., Mhamane, A., Maida, A., Georgiadi, A., Tsokanos, F. F., Klepac, K., Molocea, C. E., El-Merahbi, R., Motzler, K., Geppert, J., Karikari, R. A., Szendrodi, J., Feuchtinger, A., Hofmann, S., Karaca, S., Urlaub, H., Berriel Diaz, M., Melchior, F. & Herzig, S. EMBO Rep 24, e55981 (2023). 

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Vascular Disease Burden, Outcomes and Benefits with Empagliflozin in Heart Failure: Insights From the EMPEROR-Reduced Trial. Khan, M. S., Anker, S. D., Filippatos, G., Ferreira, J. P., Pocock, S. J., Januzzi, J. L., Chopra, V. K., Pina, I. L., Bohm, M., Ponikowski, P., Verma, S., Brueckmann, M., Vedin, O., Peil, B., Zannad, F., Packer, M. & Butler, J. J Card Fail 29, 1345-1354 (2023). 

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Ectodomain Shedding by ADAM17 Increases the Release of Soluble CD40 from Human Endothelial Cells under Pro-Inflammatory Conditions. Klersy, A., Meyer, S., Leuschner, F., Kessler, T., Hecker, M. & Wagner, A. H. Cells 12 (2023). 

Advancing Precision Medicine in Myocarditis: Current Status and Future Perspectives in Endomyocardial Biopsy-Based Diagnostics and Therapeutic Approaches. Baumeier, C., Harms, D., Aleshcheva, G., Gross, U., Escher, F. & Schultheiss, H. P. J Clin Med 12 (2023). 

Effects of aircraft noise cessation on blood pressure, cardio- and cerebrovascular endothelial function, oxidative stress, and inflammation in an experimental animal model. Bayo Jimenez, M. T., Gericke, A., Frenis, K., Rajlic, S., Kvandova, M., Kroller-Schon, S., Oelze, M., Kuntic, M., Kuntic, I., Mihalikova, D., Tang, Q., Jiang, S., Ruan, Y., Duerr, G. D., Steven, S., Schmeisser, M. J., Hahad, O., Li, H., Daiber, A. & Munzel, T. Sci Total Environ 903, 166106 (2023). 

Cardiologist-Directed Sedation Management in Patients Undergoing Transvenous Lead Extraction: A Single-Centre Retrospective Analysis. Bock, M., O'Connor, M., Chouchane, A., Schmidt, P., Schaarschmidt, C., Knoll, K., Bahlke, F., Englert, F., Storz, T., Kottmaier, M., Trenkwalder, T., Reents, T., Bourier, F., Telishevska, M., Lengauer, S., Hessling, G., Deisenhofer, I., Kolb, C. & Lennerz, C. J Clin Med 12 (2023). 

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Laser-Based 3D Body Scanning Reveals a Higher Prevalence of Abdominal Obesity than Tape Measurements: Results from a Population-Based Sample. Kosilek, R. P., Ittermann, T., Radke, D., Schipf, S., Nauck, M., Friedrich, N. & Volzke, H. Diagnostics (Basel) 13 (2023). 

Nutrition and Specific Diseases in Women during the Life Course. Makarova, N. & Zyriax, B. C. Nutrients 15 (2023). 

Ethanol Enhances Endothelial Rigidity by Targeting VE-Cadherin-Implications for Acute Aortic Dissection. Mulorz, J., Ibing, W., Cappallo, M., Brass, S. M., Takeuchi, K., Raaz, U., Schellinger, I. N., Krott, K. J., Schelzig, H., Aubin, H., Oberhuber, A., Elvers, M. & Wagenhauser, M. U. J Clin Med 12 (2023). 

Clinical and Procedural Outcomes of IVUS-Guided vs. Angiography-Guided CTO-PCI: A Systematic Review and Meta-Analysis. Panuccio, G., Abdelwahed, Y. S., Carabetta, N., Salerno, N., Leistner, D. M., Landmesser, U., De Rosa, S., Torella, D. & Werner, G. S. J Clin Med 12 (2023). 

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The assessment of left ventricular volume and function in gated small animal (18)F-FDG PET/CT imaging: a comparative study of three commercially available software tools. Zacherl, M. J., Simenhandra, A., Lindner, M., Bartenstein, P., Todica, A., Boening, G. & Fischer, M. EJNMMI Res 13, 75 (2023). 

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VV-ECMO as bridge and safety net for successful therapeutic polypragmasy in a case of influenza-triggered near-fatal asthma. Kowalewski, C., Schnurer, P., Kopp, S., Windschmitt, J., Oezkur, M., Kriege, M., Munzel, T., Kaes, J., Sagoschen, I. & Wild, J. Clin Case Rep 11, e7709 (2023). 

The diagnostic performance of quantitative flow ratio and perfusion imaging in patients with prior coronary artery disease. van Diemen, P. A., de Winter, R. W., Schumacher, S. P., Everaars, H., Bom, M. J., Jukema, R. A., Somsen, Y. B., Raijmakers, P. G., Kooistra, R. A., Timmer, J., Maaniitty, T., Robbers, L. F., von Bartheld, M. B., Demirkiran, A., van Rossum, A. C., Reiber, J. H., Knuuti, J., Underwood, R. S., Nagel, E., Knaapen, P., Driessen, R. S. & Danad, I. Eur Heart J Cardiovasc Imaging (2023). 

Maternal-derived galectin-1 shapes the placenta niche through Sda terminal glycosylation: Implication for preeclampsia. Xie, Y., Zhao, F., Freitag, N., Borowski, S., Wang, Y., Harms, C., Pang, P. C., Desforges, J., Wen, T., Schwedhelm, E., Singh, M., Dechend, R., Dell, A., Haslam, S. M., Dveksler, G., Garcia, M. G. & Blois, S. M. PNAS Nexus 2, pgad247 (2023). 

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Defining cardiac functional recovery in end-stage heart failure at single-cell resolution. Amrute, J. M., Lai, L., Ma, P., Koenig, A. L., Kamimoto, K., Bredemeyer, A., Shankar, T. S., Kuppe, C., Kadyrov, F. F., Schulte, L. J., Stoutenburg, D., Kopecky, B. J., Navankasattusas, S., Visker, J., Morris, S. A., Kramann, R., Leuschner, F., Mann, D. L., Drakos, S. G. & Lavine, K. J. Nat Cardiovasc Res 2, 399-416 (2023). 

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CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease. Doering, L., Cornean, A., Thumberger, T., Benjaminsen, J., Wittbrodt, B., Kellner, T., Hammouda, O. T., Gorenflo, M., Wittbrodt, J. & Gierten, J. Dis Model Mech 16 (2023). 

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Novel or established cryoballoon ablation system for pulmonary vein isolation: The prospective ICE-AGE-1 Study. Heeger, C. H., Popescu, S. S., Inderhees, T., Nussbickel, N., Eitel, C., Kirstein, B., Phan, H. L., Hatahet, S., Subin, B., Traub, A., Grosse, N., Kuck, K. H., Vogler, J. & Tilz, R. R. Europace (2023). 

Bleeding and Ischemic Risks of Ticagrelor Monotherapy After Coronary Interventions. Mendieta, G., Mehta, S., Baber, U., Angiolillo, D. J., Briguori, C., Cohen, D., Collier, T., Dangas, G., Dudek, D., Escaned, J., Gil, R., Vogel, B., Cao, D., Spirito, A., Huber, K., Kastrati, A., Kaul, U., Kornowski, R., Krucoff, M. W., Kunadian, V., Moliterno, D. J., Ohman, E. M., Sardella, G., Sartori, S., Sharma, S., Shlofmitz, R., Steg, P. G., Han, Y. L., Pocock, S., Gibson, C. M. & Mehran, R. J Am Coll Cardiol 82, 687-700 (2023). 

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Identification of Maleimide-Fused Carbazoles as Novel Noncanonical Bone Morphogenetic Protein Synergizers. Riege, D., Herschel, S., Heintze, L., Fenkl, T., Wesseler, F., Sievers, S., Peifer, C. & Schade, D. ACS Pharmacol Transl Sci 6, 1207-1220 (2023). 

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Plasma Soluble Glycoprotein VI, Platelet Function, Bleeding, and Ischemic Events in Patients Undergoing Elective Percutaneous Coronary Intervention. Lahu, S., Adler, K., Mayer, K., Hein-Rothweiler, R., Bernlochner, I., Ndrepepa, G., Schupke, S., Holdenrieder, S., Bongiovanni, D., Laugwitz, K. L., Schunkert, H., Gawaz, M., Massberg, S., Kastrati, A. & Munch, G. Thromb Haemost (2023). 

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Half-Dose versus Single-Dose Gadobutrol for Extracellular Volume Measurements in Cardiac Magnetic Resonance. Doeblin, P., Steinbeis, F., Witzenrath, M., Hashemi, D., Chen, W., Weiss, K. J., Stawowy, P. & Kelle, S. J Cardiovasc Dev Dis 10 (2023). 

Transcatheter interventions for left-sided valvular heart disease complicated by cardiogenic shock: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) in collaboration with the Association for Acute Cardiovascular (ACVC) and the ESC Working Group on Cardiovascular Surgery. Fraccaro, C., Karam, N., Mollmann, H., Bleiziffer, S., Bonaros, N., Teles, R. C., Carrilho Ferreira, P., Chieffo, A., Czerny, M., Donal, E., Dudek, D., Dumonteil, N., Esposito, G., Fournier, S., Hassager, C., Kim, W. K., Krychtiuk, K. A., Mehilli, J., Pregowski, J., Stefanini, G. G., Ternacle, J., Thiele, H., Thielmann, M., Vincent, F., von Bardeleben, R. S. & Tarantini, G. EuroIntervention (2023). 

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The Effects of Hospitalisation on the Serum Metabolome in COVID-19 Patients. Hensen, T., Fassler, D., O'Mahony, L., Albrich, W. C., Barda, B., Garzoni, C., Kleger, G. R., Pietsch, U., Suh, N., Hertel, J. & Thiele, I. Metabolites 13 (2023). 

Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes. Kirchhof, P., Toennis, T., Goette, A., Camm, A. J., Diener, H. C., Becher, N., Bertaglia, E., Blomstrom Lundqvist, C., Borlich, M., Brandes, A., Cabanelas, N., Calvert, M., Chlouverakis, G., Dan, G. A., de Groot, J. R., Dichtl, W., Kravchuk, B., Lubinski, A., Marijon, E., Merkely, B., Mont, L., Ozga, A. K., Rajappan, K., Sarkozy, A., Scherr, D., Sznajder, R., Velchev, V., Wichterle, D., Sehner, S., Simantirakis, E., Lip, G. Y. H., Vardas, P., Schotten, U., Zapf, A. & Investigators, N.-A. N Engl J Med (2023). 

An arrhythmogenic metabolite in atrial fibrillation. Krause, J., Nickel, A., Madsen, A., Aitken-Buck, H. M., Stoter, A. M. S., Schrapers, J., Ojeda, F., Geiger, K., Kern, M., Kohlhaas, M., Bertero, E., Hofmockel, P., Hubner, F., Assum, I., Heinig, M., Muller, C., Hansen, A., Krause, T., Park, D. D., Just, S., Aissi, D., Bornigen, D., Lindner, D., Friedrich, N., Alhussini, K., Bening, C., Schnabel, R. B., Karakas, M., Iacoviello, L., Salomaa, V., Linneberg, A., Tunstall-Pedoe, H., Kuulasmaa, K., Kirchhof, P., Blankenberg, S., Christ, T., Eschenhagen, T., Lamberts, R. R., Maack, C., Stenzig, J. & Zeller, T. J Transl Med 21, 566 (2023). 

Blinded Withdrawal of Long-Term Randomized Treatment With Empagliflozin or Placebo in Patients With Heart Failure. Packer, M., Butler, J., Zeller, C., Pocock, S. J., Brueckmann, M., Ferreira, J. P., Filippatos, G., Usman, M. S., Zannad, F. & Anker, S. D. Circulation (2023). 

Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis. Wang, Z., Zhang, X., Lu, S., Zhang, C., Ma, Z., Su, R., Li, Y., Sun, T., Li, Y., Hong, M., Deng, X., Monjezi, M. R., Hristov, M., Steffens, S., Santovito, D., Dornmair, K., Ley, K., Weber, C., Mohanta, S. K., Habenicht, A. J. R. & Yin, C. Nat Cardiovasc Res 2, 290-306 (2023). 

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Functional Cardiovascular Characterization of the Common Marmoset (Callithrix jacchus). Klosener, L., Samolovac, S., Barnekow, I., Konig, J., Moussavi, A., Boretius, S., Fuchs, D., Haegens, A., Hinkel, R. & Mietsch, M. Biology (Basel) 12 (2023). 

Cross-Talk of NADPH Oxidases and Inflammation in Obesity. Morawietz, H., Brendel, H., Diaba-Nuhoho, P., Catar, R., Perakakis, N., Wolfrum, C. & Bornstein, S. R. Antioxidants (Basel) 12 (2023). 

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Diabetes Mellitus and Its Association with Adverse In-Hospital Outcomes in Patients with COVID-19-A Nationwide Study. Schmitt, V. H., Hobohm, L., Sagoschen, I., Sivanathan, V., Hahad, O., Espinola-Klein, C., Munzel, T. & Keller, K. Viruses 15 (2023). 

Prognostic Value of the AST/ALT Ratio versus Bilirubin in Patients with Cardiogenic Shock. Schupp, T., Rusnak, J., Weidner, K., Ruka, M., Egner-Walter, S., Dudda, J., Forner, J., Bertsch, T., Mashayekhi, K., Ayoub, M., Akin, M., Kittel, M., Behnes, M. & Akin, I. J Clin Med 12 (2023). 

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Generation of a homozygous CRYAB p.Arg120Gly mutant (UKEi001-A-1) from a human iPSC line. Pietsch, N., Cheng, J., Fazio, A., Ewald, L., Alizoti, E., Kramer, E., Orthey, E., Carrier, L. & Singh, S. R. Stem Cell Res 71, 103188 (2023). 

Efficacy of ferric carboxymaltose in heart failure with iron deficiency: an individual patient data meta-analysis. Ponikowski, P., Mentz, R. J., Hernandez, A. F., Butler, J., Khan, M. S., van Veldhuisen, D. J., Roubert, B., Blackman, N., Friede, T., Jankowska, E. A. & Anker, S. D. Eur Heart J 44, 5077-5091 (2023). 

Sarcopenic obesity using the ESPEN and EASO consensus statement criteria of 2022 - Results from the German KORA-Age study. Schluessel, S., Huemer, M. T., Peters, A., Drey, M. & Thorand, B. Obes Res Clin Pract (2023). 

Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction. Stahli, B. E., Varbella, F., Linke, A., Schwarz, B., Felix, S. B., Seiffert, M., Kesterke, R., Nordbeck, P., Witzenbichler, B., Lang, I. M., Kessler, M., Valina, C., Dibra, A., Rohla, M., Moccetti, M., Vercellino, M., Gaede, L., Bott-Flugel, L., Jakob, P., Stehli, J., Candreva, A., Templin, C., Schindler, M., Wischnewsky, M., Zanda, G., Quadri, G., Mangner, N., Toma, A., Magnani, G., Clemmensen, P., Luscher, T. F., Munzel, T., Schulze, P. C., Laugwitz, K. L., Rottbauer, W., Huber, K., Neumann, F. J., Schneider, S., Weidinger, F., Achenbach, S., Richardt, G., Kastrati, A., Ford, I., Maier, W., Ruschitzka, F. & Investigators, M. A. N Engl J Med (2023). 

Extracorporeal Life Support in Infarct-Related Cardiogenic Shock. Thiele, H., Zeymer, U., Akin, I., Behnes, M., Rassaf, T., Mahabadi, A. A., Lehmann, R., Eitel, I., Graf, T., Seidler, T., Schuster, A., Skurk, C., Duerschmied, D., Clemmensen, P., Hennersdorf, M., Fichtlscherer, S., Voigt, I., Seyfarth, M., John, S., Ewen, S., Linke, A., Tigges, E., Nordbeck, P., Bruch, L., Jung, C., Franz, J., Lauten, P., Goslar, T., Feistritzer, H. J., Poss, J., Kirchhof, E., Ouarrak, T., Schneider, S., Desch, S., Freund, A. & Investigators, E.-S. N Engl J Med (2023). 

Dipeptidyl peptidase 3 plasma levels predict cardiogenic shock and mortality in acute coronary syndromes. Wenzl, F. A., Bruno, F., Kraler, S., Klingenberg, R., Akhmedov, A., Ministrini, S., Santos, K., Godly, K., Godly, J., Niederseer, D., Manka, R., Bergmann, A., Camici, G. G., von Eckardstein, A., Stahli, B., Muller, O., Roffi, M., Raber, L. & Luscher, T. F. Eur Heart J (2023). 

Burnout, self-rated general health and life satisfaction among teachers and other academic occupational groups. Beutel, T., Koestner, C., Wild, P. S., Munzel, T., Beutel, M. E., Lackner, K. J., Pfeiffer, N., Nubling, M., Becker, J. & Letzel, S. Front Public Health 11, 1209995 (2023). 

Can single-cell and spatial omics unravel the pathophysiology of pre-eclampsia? Hartmann, S., Botha, S. M., Gray, C. M., Valdes, D. S., Tong, S., Kaitu'u-Lino, T. J., Herse, F., Bergman, L., Cluver, C. A., Dechend, R. & Nonn, O. J Reprod Immunol 159, 104136 (2023). 

Removal of Wall-Adherent Inferior Vena Cava Thrombus with a Combined Approach Using Vacuum-Assisted Thrombectomy and a Rotational Thrombectomy Device. Kaemmel, J., Heck, R., Lanmuller, P., Falk, V. & Starck, C. Case Rep Vasc Med 2023, 5178998 (2023). 

Impact of myocardial deformation on risk prediction in patients following acute myocardial infarction. Lange, T., Gertz, R. J., Schulz, A., Backhaus, S. J., Evertz, R., Kowallick, J. T., Hasenfuss, G., Desch, S., Thiele, H., Stiermaier, T., Eitel, I. & Schuster, A. Front Cardiovasc Med 10, 1199936 (2023). 

Factors Associated With Circulating Sex Hormones in Men : Individual Participant Data Meta-analyses. Marriott, R. J., Murray, K., Adams, R. J., Antonio, L., Ballantyne, C. M., Bauer, D. C., Bhasin, S., Biggs, M. L., Cawthon, P. M., Couper, D. J., Dobs, A. S., Flicker, L., Handelsman, D. J., Hankey, G. J., Hannemann, A., Haring, R., Hsu, B., Karlsson, M., Martin, S. A., Matsumoto, A. M., Mellstrom, D., Ohlsson, C., O'Neill, T. W., Orwoll, E. S., Quartagno, M., Shores, M. M., Steveling, A., Tivesten, A., Travison, T. G., Vanderschueren, D., Wittert, G. A., Wu, F. C. W. & Yeap, B. B. Ann Intern Med (2023). 

Comprehensive identification of diverse ribosomal RNA modifications by targeted nanopore direct RNA sequencing and JACUSA2. Naarmann-de Vries, I. S., Zorbas, C., Lemsara, A., Piechotta, M., Ernst, F. G. M., Wacheul, L., Lafontaine, D. L. J. & Dieterich, C. RNA Biol 20, 652-665 (2023). 

Infarct severity and outcomes in ST-elevation myocardial infarction patients without standard modifiable risk factors - A multicenter cardiac magnetic resonance study. Reindl, M., Stiermaier, T., Lechner, I., Tiller, C., Holzknecht, M., Fink, P., Mayr, A., Klug, G., Feistritzer, H. J., Delewi, R., Hirsch, A., Carberry, J., Carrick, D., Bauer, A., Metzler, B., Nijveldt, R., Thiele, H., Berry, C., Eitel, I. & Reinstadler, S. J. Eur J Intern Med (2023). 

Nonthermal Point-by-Point Pulmonary Vein Isolation Using a Novel Pulsed Field Ablation System. Wenzel, J. P., Lemoine, M. D., Rottner, L., My, I., Moser, F., Obergassel, J., Nies, M., Riess, J., Ismaili, D., Nikorowitsch, J., Ouyang, F., Kirchhof, P., Rillig, A., Metzner, A. & Reissmann, B. Circ Arrhythm Electrophysiol, e012093 (2023). 

Neutrophils for Revascularization Require Activation of CCR6 and CCL20 by TNFalpha. Lorchner, H., Canes Esteve, L., Goes, M. E., Harzenetter, R., Brachmann, N., Gajawada, P., Gunther, S., Doll, N., Poling, J. & Braun, T. Circ Res 133, 592-610 (2023). 

Comparison of transcatheter leaflet-approximation and direct annuloplasty in tricuspid regurgitation. Ochs, L., Korber, M. I., Wienemann, H., Tichelbacker, T., Iliadis, C., Metze, C., Bruwer, M., Schmidt, T., Omran, H., Fortmeier, V., Friedrich, K., Rudolph, V., Baldus, S. & Pfister, R. Clin Res Cardiol (2023). 

Are there associations between hip geometry and bone quality? An analysis on 3074 adults from a general population. Fischer, C. S., Ittermann, T., Hannemann, A., Schmidt, C. O., Mederake, M., Schull, D., Histing, T., Lange, J. & Haralambiev, L. Arch Orthop Trauma Surg (2023). 

Modification of the GRACE Risk Score for Risk Prediction in Patients With Acute Coronary Syndromes. Georgiopoulos, G., Kraler, S., Mueller-Hennessen, M., Delialis, D., Mavraganis, G., Sopova, K., Wenzl, F. A., Raber, L., Biener, M., Stahli, B. E., Maneta, E., Spray, L., Iglesias, J. F., Coelho-Lima, J., Tual-Chalot, S., Muller, O., Mach, F., Frey, N., Duerschmied, D., Langer, H. F., Katus, H., Roffi, M., Camici, G. G., Mueller, C., Giannitsis, E., Spyridopoulos, I., Luscher, T. F., Stellos, K. & Stamatelopoulos, K. JAMA Cardiol (2023). 

Effect of cardiopulmonary bypass on plasma and erythrocytes oxylipins. Liu, T., Dogan, I., Rothe, M., Potapov, E., Schoenrath, F., Gollasch, M., Luft, F. C. & Gollasch, B. Lipids Health Dis 22, 138 (2023). 

Global Burden of Atrial Fibrillation and Flutter by National Income: Results From the Global Burden of Disease 2019 Database. Ohlrogge, A. H., Brederecke, J. & Schnabel, R. B. J Am Heart Assoc 12, e030438 (2023). 

Sleep characteristics and parameters of bone turnover and strength in the adult population: results from the Study of Health in Pomerania-TREND. Rassow, K., Obst, A., Nauck, M., Volzke, H., Stubbe, B., Fietze, I., Penzel, T., Ewert, R. & Hannemann, A. J Sleep Res, e14019 (2023). 

Medical care and biomarker-based assessment of mortality in two cohorts of patients with chronic coronary syndrome 10 years apart. Rehm, M., Jaensch, A., Schottker, B., Mons, U., Hahmann, H., Koenig, W., Brenner, H. & Rothenbacher, D. BMC Cardiovasc Disord 23, 428 (2023). 

Patient-Reported Long-Term Outcome of Balloon Pulmonary Angioplasty for Inoperable CTEPH. Wiedenroth, C. B., Steinhaus, K., Rolf, A., Breithecker, A., Adameit, M. S. D., Kriechbaum, S. D., Haas, M., Roller, F., Hamm, C. W., Ghofrani, H. A., Mayer, E., Guth, S. & Liebetrau, C. Thorac Cardiovasc Surg (2023). 

Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials. Zeymer, U., Freund, A., Hochadel, M., Ostadal, P., Belohlavek, J., Rokyta, R., Massberg, S., Brunner, S., Lusebrink, E., Flather, M., Adlam, D., Bogaerts, K., Banning, A., Sabate, M., Akin, I., Jobs, A., Schneider, S., Desch, S. & Thiele, H. Lancet 402, 1338-1346 (2023). 

Transcatheter Aortic Valve Replacement for Isolated Aortic Regurgitation Using a New Self-Expanding TAVR System. Adam, M., Tamm, A., Wienemann, H., Unbehaun, A., Klein, C., Arnold, M., Marwan, M., Theiss, H., Braun, D., Bleiziffer, S., Geyer, M., Goncharov, A., Kuhn, E., Falk, V., von Bardeleben, R. S., Achenbach, S., Massberg, S., Baldus, S., Treede, H. & Rudolph, T. K. JACC Cardiovasc Interv 16, 1965-1973 (2023). 

Developmental dynamics of homoarginine, ADMA and SDMA plasma levels from birth to adolescence. Baach, F., Meyer, B., Oh, J., Lezius, S., Boger, R., Schwedhelm, E., Choe, C. U. & Neu, A. Amino Acids (2023). 

Trends in renal function in Northern Sweden 1986-2014: data from the seven cross-sectional surveys within the Northern Sweden MONICA study. de Man Lapidoth, J., Hultdin, J., Jonsson, P. A., Eriksson Svensson, M., Wennberg, M., Zeller, T. & Soderberg, S. BMJ Open 13, e072664 (2023). 

Widespread effects of DNA methylation and intra-motif dependencies revealed by novel transcription factor binding models. Grau, J., Schmidt, F. & Schulz, M. H. Nucleic Acids Res 51, e95 (2023). 

Differentiating primary sarcomeric hypertrophic cardiomyopathy from Noonan syndrome: can the electrocardiogram be of use? Hauptmeijer, R. W. L., Lippert, L., Ten Cate, F., Fejzic, Z., Leenders, E., Wolf, C. M. & Draaisma, J. M. T. Cardiol Young, 1-7 (2023). 

Single-nuclear transcriptome profiling identifies persistent fibroblast activation in hypertrophic and failing human hearts of patients with longstanding disease. Kattih, B., Boeckling, F., Shumliakivska, M., Tombor, L., Rasper, T., Schmitz, K., Hoffmann, J., Nicin, L., Abplanalp, W. T., Carstens, D. C., Arsalan, M., Emrich, F., Holubec, T., Walther, T., Puntmann, V. O., Nagel, E., John, D., Zeiher, A. M. & Dimmeler, S. Cardiovasc Res (2023). 

Insights into the daily life of ventricular assist device coordinators-Outcome of an international questionnaire. Mulzer, J., Kaufmann, F., Mueller, M., Potapov, E. & Knierim, J. Artif Organs (2023). 

A randomized vagus nerve stimulation study demonstrates that serum aldosterone levels decrease with age in women, but not in men. Veiz, E., Kieslich, S. K., Czesnik, D., Herrmann-Lingen, C., Meyer, T. & Staab, J. Sci Rep 13, 14197 (2023). 

RNA-Binding Proteins Regulate Post-Transcriptional Responses to TGF-beta to Coordinate Function and Mesenchymal Activation of Murine Endothelial Cells. Wardman, R., Keles, M., Pachkiv, I., Hemanna, S., Grein, S., Schwarz, J., Stein, F., Ola, R., Dobreva, G., Hentze, M. W. & Heineke, J. Arterioscler Thromb Vasc Biol 43, 1967-1989 (2023). 

Impact of educational attainment on preventive efforts after myocardial infarction: results of the IPP and NET-IPP trials. Wienbergen, H., Fach, A., Winzer, E. B., Schmucker, J., Hanses, U., Retzlaff, T., Ruhle, S., Litfin, C., Kerniss, H., Marin, L. A. M., Elsasser, A., Gielen, S., Eitel, I., Linke, A., Hambrecht, R. & Osteresch, R. Clin Res Cardiol (2023).



Paper of the Month

Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease. Ziegler, K. A., Ahles, A., Dueck, A., Esfandyari, D., Pichler, P., Weber, K., Kotschi, S., Bartelt, A., Sinicina, I., Graw, M., Leonhardt, H., Weckbach, L. T., Massberg, S., Schifferer, M., Simons, M., Hoeher, L., Luo, J., Erturk, A., Schiattarella, G. G., Sassi, Y., Misgeld, T. & Engelhardt, S. Science 381, 285-290 (2023).

Non-eligibility for pivotal HFpEF/HFmrEF outcome trials and mortality in a contemporary heart failure cohort. Santner, V., Riepl, H. S., Posch, F., Wallner, M., Rainer, P. P., Ablasser, K., Kolesnik, E., Hoeller, V., Zach, D., Schwegel, N., Kreuzer, P., Lueger, A., Petutschnigg, J., Pieske, B., Zirlik, A., Edelmann, F. & Verheyen, N. Eur J Intern Med (2023).

Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration. Ni, W., Nikolaou, N., Ward-Caviness, C. K., Breitner, S., Wolf, K., Zhang, S., Wilson, R., Waldenberger, M., Peters, A. & Schneider, A. Environ Int 178, 108109 (2023).

Goody two plasmids: An optimized transient transfection system for AAV vector production. Moreno Velasquez, S. D., Gerstmann, E. & Grimm, D. Mol Ther Methods Clin Dev 30, 191-193 (2023).

Redo-TAVI with SAPIEN 3 in SAPIEN XT or SAPIEN 3 - impact of pre- and post-dilatation on final THV expansion. Meier, D., Landes, U., Sondergaard, L., De Backer, O., Lutter, G., Puehler, T., Akodad, M., Tzimas, G., Blanke, P., Payne, G. W., Lai, A., Gill, H., Wood, D. A., Webb, J. G., Sellers, S. L. & Sathananthan, J.EuroIntervention 19, 757-765 (2023).

Mind the gap: Leak currents and induced pluripotent stem cell-derived cardiomyocytes in translational cardiac electrophysiology. Heijman, J. & Christ, T. Europace (2023).

Machine-learning based prediction of in-hospital death for patients with takotsubo syndrome: the InterTAK-ML model. De Filippo, O., Cammann, V. L., Pancotti, C., Di Vece, D., Silverio, A., Schweiger, V., Niederseer, D., Szawan, K. A., Wurdinger, M., Koleva, I., Dusi, V., Bellino, M., Vecchione, C., Parodi, G., Bossone, E., Gili, S., Neuhaus, M., Franke, J., Meder, B., Jaguszewski, M., Noutsias, M., Knorr, M., Jansen, T., Dichtl, W., von Lewinski, D., Burgdorf, C., Kherad, B., Tschope, C., Sarcon, A., Shinbane, J., Rajan, L., Michels, G., Pfister, R., Cuneo, A., Jacobshagen, C., Karakas, M., Koenig, W., Pott, A., Meyer, P., Roffi, M., Banning, A., Wolfrum, M., Cuculi, F., Kobza, R., Fischer, T. A., Vasankari, T., Airaksinen, K. E. J., Napp, L. C., Dworakowski, R., MacCarthy, P., Kaiser, C., Osswald, S., Galiuto, L., Chan, C., Bridgman, P., Beug, D., Delmas, C., Lairez, O., Gilyarova, E., Shilova, A., Gilyarov, M., El-Battrawy, I., Akin, I., Polednikova, K., Tousek, P., Winchester, D. E., Massoomi, M., Galuszka, J., Ukena, C., Poglajen, G., Carrilho-Ferreira, P., Hauck, C., Paolini, C., Bilato, C., Kobayashi, Y., Kato, K., Ishibashi, I., Himi, T., Din, J., Al-Shammari, A., Prasad, A., Rihal, C. S., Liu, K., Schulze, P. C., Bianco, M., Jorg, L., Rickli, H., Pestana, G., Nguyen, T. H., Bohm, M., Maier, L. S., Pinto, F. J., Widimsky, P., Felix, S. B., Braun-Dullaeus, R. C., Rottbauer, W., Hasenfuss, G., Pieske, B. M., Schunkert, H., Budnik, M., Opolski, G., Thiele, H., Bauersachs, J., Horowitz, J. D., Di Mario, C., Bruno, F., Kong, W., Dalakoti, M., Imori, Y., Munzel, T., Crea, F., Luscher, T. F., Bax, J. J., Ruschitzka, F., de Ferrari, G. M., Fariselli, P., Ghadri, J. R., Citro, R., D'Ascenzo, F. & Templin, C. Eur J Heart Fail (2023).

New-onset atrial fibrillation after percutaneous patent foramen ovale closure: a meta-analysis. Jurczyk, D., Macherey-Meyer, S., Rawish, E., Stiermaier, T., Eitel, I., Frerker, C. & Schmidt, T. Clin Res Cardiol(2023).

Neurological symptoms after COVID-19 vaccination: a report on the clinical presentation of the first 50 patients. Gerhard, A., Raeder, V., Pernice, H. F., Boesl, F., Schroeder, M., Richter, J., Endres, M., Pruss, H., Hahn, K., Audebert, H. J. & Franke, C. J Neurol 270, 4673-4677 (2023).

Reply to Letter: Potential problems with concomitant therapy with Impella(R) and veno-arterial extracorporeal membrane oxygenation in patients with cardiac arrest. Thevathasan, T., Landmesser, U. & Skurk, C. Resuscitation 190, 109915 (2023).

Penumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial. Poli, S., Mbroh, J., Baron, J. C., Singhal, A. B., Strbian, D., Molina, C., Lemmens, R., Turc, G., Mikulik, R., Michel, P., Tatlisumak, T., Audebert, H. J., Dichgans, M., Veltkamp, R., Husing, J., Graessner, H., Fiehler, J., Montaner, J., Adeyemi, A. K., Althaus, K., Arenillas, J. F., Bender, B., Benedikt, F., Broocks, G., Burghaus, I., Cardona, P., Deb-Chatterji, M., Cvikova, M., Defreyne, L., De Herdt, V., Detante, O., Ernemann, U., Flottmann, F., Garcia Guillamon, L., Glauch, M., Gomez-Exposito, A., Gory, B., Sylvie Grand, S., Harsany, M., Hauser, T. K., Heck, O., Hemelsoet, D., Hennersdorf, F., Hoppe, J., Kalmbach, P., Kellert, L., Kohrmann, M., Kowarik, M., Lara-Rodriguez, B., Legris, L., Lindig, T., Luntz, S., Lusk, J., Mac Grory, B., Manger, A., Martinez-Majander, N., Mengel, A., Meyne, J., Muller, S., Mundiyanapurath, S., Naggara, O., Nedeltchev, K., Nguyen, T. N., Nilsson, M. A., Obadia, M., Poli, K., Purrucker, J. C., Raty, S., Richard, S., Richter, H., Schilte, C., Schlemm, E., Stohr, L., Stolte, B., Sykora, M., Thomalla, G., Tomppo, L., van Horn, N., Zeller, J., Ziemann, U., Zuern, C. S., Hartig, F., Tuennerhoff, J. & investigators, P. Int J Stroke, 17474930231185275 (2023).

Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage. Beck, C., Ramanujam, D., Vaccarello, P., Widenmeyer, F., Feuerherd, M., Cheng, C. C., Bomhard, A., Abikeeva, T., Schadler, J., Sperhake, J. P., Graw, M., Safi, S., Hoffmann, H., Staab-Weijnitz, C. A., Rad, R., Protzer, U., Frischmuth, T. & Engelhardt, S. Nat Commun 14, 4564 (2023).

Cardiac defibrillator implantation in patients with syncope and inducible ventricular arrhythmia: insights from the German Device Registry. Kahle, A. K., Senges, J., Hochadel, M., Brachmann, J., Thomas, D., Straube, F., Bonaventura, K., Larbig, R., Werner, N., Butter, C., Alken, F. A. & Meyer, C. Sci Rep 13, 12182 (2023).

Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke. Brunner, C., Denis, N. L., Gertz, K., Grillet, M., Montaldo, G., Endres, M. & Urban, A. J Cereb Blood Flow Metab, 271678X231191600 (2023).

Body composition markers from classic anthropometry, bioelectrical impedance analysis, and magnetic resonance imaging are associated with inflammatory markers in the general population. Bibi, S., Naeem, M., Bahls, M., Dorr, M., Friedrich, N., Nauck, M., Bulow, R., Volzke, H., Paulista Markus, M. R. & Ittermann, T. Nutr Metab Cardiovasc Dis 33, 1899-1906 (2023).

A transient increase of HIF-1alpha during the G1 phase (G1-HIF) ensures cell survival under nutritional stress. Belapurkar, R., Pfisterer, M., Dreute, J., Werner, S., Zukunft, S., Fleming, I., Kracht, M. & Schmitz, M. L. Cell Death Dis 14, 477 (2023).

Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study. Yao, Y., Schneider, A., Wolf, K., Zhang, S., Wang-Sattler, R., Peters, A. & Breitner, S. Sci Total Environ 900, 165780 (2023).

Circulating metabolites modulated by diet are associated with depression. van der Spek, A., Stewart, I. D., Kuhnel, B., Pietzner, M., Alshehri, T., Gauss, F., Hysi, P. G., MahmoudianDehkordi, S., Heinken, A., Luik, A. I., Ladwig, K. H., Kastenmuller, G., Menni, C., Hertel, J., Ikram, M. A., de Mutsert, R., Suhre, K., Gieger, C., Strauch, K., Volzke, H., Meitinger, T., Mangino, M., Flaquer, A., Waldenberger, M., Peters, A., Thiele, I., Kaddurah-Daouk, R., Dunlop, B. W., Rosendaal, F. R., Wareham, N. J., Spector, T. D., Kunze, S., Grabe, H. J., Mook-Kanamori, D. O., Langenberg, C., van Duijn, C. M. & Amin, N. Mol Psychiatry (2023).

Early versus delayed coronary angiography in patients with out-of-hospital cardiac arrest and no ST-segment elevation: a systematic review and meta-analysis of randomized controlled trials. Hamidi, F., Anwari, E., Spaulding, C., Hauw-Berlemont, C., Vilfaillot, A., Viana-Tejedor, A., Kern, K. B., Hsu, C. H., Bergmark, B. A., Qamar, A., Bhatt, D. L., Furtado, R. H. M., Myhre, P. L., Hengstenberg, C., Lang, I. M., Frey, N., Freund, A., Desch, S., Thiele, H., Preusch, M. R. & Zelniker, T. A. Clin Res Cardiol (2023).

In Memoriam: Prof. Dr. Jeanette Erdmann (1965-2023). Schunkert, H. & Aherrahrou, Z. Circ Genom Precis Med 16, 315-316 (2023).

Endovascular therapy in patients with internal carotid artery occlusion and patent circle of Willis. Riegler, C., von Rennenberg, R., Bollweg, K., Nguyen, T. N., Kleine, J. F., Tiedt, S., Audebert, H. J., Siebert, E. & Nolte, C. H. J Neurointerv Surg (2023).

Laser lead extraction in octo- and nonagenarians. A subgroup analysis from the GALLERY registry. Pecha, S., Chung, D. U., Burger, H., Osswald, B., Ghaffari, N., Knaut, M., Reichenspurner, H., Willems, S., Butter, C., Hakmi, S. & investigators, G. J Cardiovasc Electrophysiol (2023).

Association of plasma chemerin with all-cause and disease-specific mortality - results from a population-based study. Noppes, K., Gross, S., Hannemann, A., Markus, M. R. P., Bahls, M., Volzke, H., Dorr, M., Nauck, M., Friedrich, N. & Zylla, S. Int J Obes (Lond) 47, 956-962 (2023).

Inflammation and cardiovascular disease: new epidemiologic data and their potential implications for anti-cytokine therapy. Koenig, W. & Sager, H. B. Eur J Prev Cardiol 30, 1728-1730 (2023).

Description of a new clinical syndrome: thoracic constriction without evidence of the typical funnel-shaped depression-the "invisible" pectus excavatum. Hohneck, A., Ansari, U., Natale, M., Wittig, K., Overhoff, D., Riffel, P., Boettcher, M., Akin, I., Duerschmied, D. & Papavassiliu, T. Sci Rep 13, 12036 (2023).

Lifestyle interventions to change trajectories of obesity-related cardiovascular risk from childhood onset to manifestation in adulthood: a joint scientific statement of the task force for childhood health of the European Association of Preventive Cardiology and the European Childhood Obesity Group. Hanssen, H., Moholdt, T., Bahls, M., Biffi, A., Siegrist, M., Lewandowski, A. J., Biondi-Zoccai, G., Cavarretta, E., Kokkvoll, A., Lochen, M. L., Maestrini, V., Pinto, R. S., Palermi, S., Thivel, D., Wojcik, M., Hansen, D., Van Craenenbroeck, E. M., Weghuber, D., Kraenkel, N. & Tiberi, M. Eur J Prev Cardiol 30, 1462-1472 (2023).

A network medicine approach to study comorbidities in heart failure with preserved ejection fraction. Lanzer, J. D., Valdeolivas, A., Pepin, M., Hund, H., Backs, J., Frey, N., Friederich, H. C., Schultz, J. H., Saez-Rodriguez, J. & Levinson, R. T. BMC Med 21, 267 (2023).

SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations. Banerjee, K., Lin, Y., Gahn, J., Cordero, J., Gupta, P., Mohamed, I., Graupera, M., Dobreva, G., Schwartz, M. A. & Ola, R. J Clin Invest 133 (2023).

Prospective collection of blood plasma samples to identify potential biomarkers for the prehospital stroke diagnosis (ProGrEss-Bio): study protocol for a multicenter prospective observational study. Geisler, F., Haacke, L., Lorenz, M., Schwabauer, E., Wendt, M., Bernhardt, L., Dashti, E., Freitag, E., Kunz, A., Hofmann-Shen, C., Zuber, M., Waldschmidt, C., Kandil, F. I., Kappert, K., Dang-Heine, C., Lorenz-Meyer, I., Audebert, H. J. & Weber, J. E. Front Neurol 14, 1201130 (2023).

Circulating microRNAs predict recurrence and death following venous thromboembolism. Ten Cate, V., Rapp, S., Schulz, A., Pallares Robles, A., Jurk, K., Koeck, T., Espinola-Klein, C., Halank, M., Seyfarth, H. J., Beutel, M. E., Schuster, A. K., Marini, F., Hobohm, L., Lankeit, M., Lackner, K. J., Ruf, W., Munzel, T., Andrade-Navarro, M. A., Prochaska, J. H., Konstantinides, S. V. & Wild, P. S. J Thromb Haemost 21, 2797-2810 (2023).

ASSURED-optimized CRISPR protocol for knockout/SNP knockin in hiPSCs. Ludwik, K. A., Telugu, N., Schommer, S., Stachelscheid, H. & Diecke, S. STAR Protoc 4, 102406 (2023).

Circular RNA circPLOD2 regulates pericyte function by targeting the transcription factor KLF4. Glaser, S. F., Brezski, A., Baumgarten, N., Klangwart, M., Heumuller, A. W., Maji, R. K., Leisegang, M. S., Guenther, S., Zehendner, C. M., John, D., Schulz, M. H., Zarnack, K. & Dimmeler, S. Cell Rep 42, 112824 (2023).

Heart failure & the Heart-Brain axis. Doehner, W., Jelena, C., Yilmaz, M. B. & Coats, A. J. QJM (2023).

Circulating microRNAs predict recurrence and death following venous thromboembolism. Cate, V. T., Rapp, S., Schulz, A., Pallares Robles, A., Jurk, K., Koeck, T., Espinola-Klein, C., Halank, M., Seyfarth, H. J., Beutel, M. E., Schuster, A. K., Marini, F., Hobohm, L., Lankeit, M., Lackner, K. J., Ruf, W., Munzel, T., Andrade-Navarro, M. A., Prochaska, J. H., Konstantinides, S. V. & Wild, P. S. J Thromb Haemost (2023).

Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease. Kucherenko, M. M., Sang, P., Yao, J., Gransar, T., Dhital, S., Grune, J., Simmons, S., Michalick, L., Wulsten, D., Thiele, M., Shomroni, O., Hennig, F., Yeter, R., Solowjowa, N., Salinas, G., Duda, G. N., Falk, V., Vyavahare, N. R., Kuebler, W. M. & Knosalla, C. Nat Commun 14, 4416 (2023).

Quantum iterative reconstruction on a photon-counting detector CT improves the quality of hepatocellular carcinoma imaging. Graafen, D., Stoehr, F., Halfmann, M. C., Emrich, T., Foerster, F., Yang, Y., Duber, C., Muller, L. & Kloeckner, R. Cancer Imaging 23, 69 (2023).

Force generation in human blood platelets by filamentous actomyosin structures. Zelena, A., Blumberg, J., Probst, D., Gerasimaite, R., Lukinavicius, G., Schwarz, U. S. & Koster, S. Biophys J 122, 3340-3353 (2023).

Multi-omics in thoracic aortic aneurysm: the complex road to the simplification. Rega, S., Farina, F., Bouhuis, S., de Donato, S., Chiesa, M., Poggio, P., Cavallotti, L., Bonalumi, G., Giambuzzi, I., Pompilio, G. & Perrucci, G. L. Cell Biosci 13, 131 (2023).

De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis. Gorog, D. A., Ferreiro, J. L., Ahrens, I., Ako, J., Geisler, T., Halvorsen, S., Huber, K., Jeong, Y. H., Navarese, E. P., Rubboli, A., Sibbing, D., Siller-Matula, J. M., Storey, R. F., Tan, J. W. C., Ten Berg, J. M., Valgimigli, M., Vandenbriele, C. & Lip, G. Y. H. Nat Rev Cardiol (2023).

4D Flow cardiovascular magnetic resonance consensus statement: 2023 update. Bissell, M. M., Raimondi, F., Ait Ali, L., Allen, B. D., Barker, A. J., Bolger, A., Burris, N., Carhall, C. J., Collins, J. D., Ebbers, T., Francois, C. J., Frydrychowicz, A., Garg, P., Geiger, J., Ha, H., Hennemuth, A., Hope, M. D., Hsiao, A., Johnson, K., Kozerke, S., Ma, L. E., Markl, M., Martins, D., Messina, M., Oechtering, T. H., van Ooij, P., Rigsby, C., Rodriguez-Palomares, J., Roest, A. A. W., Roldan-Alzate, A., Schnell, S., Sotelo, J., Stuber, M., Syed, A. B., Toger, J., van der Geest, R., Westenberg, J., Zhong, L., Zhong, Y., Wieben, O. & Dyverfeldt, P. J Cardiovasc. Reson 25, 40 (2023).

EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy. Algul, S., Schuldt, M., Manders, E., Jansen, V., Schlossarek, S., de Goeij-de Haas, R., Henneman, A. A., Piersma, S. R., Jimenez, C. R., Michels, M., Carrier, L., Helmes, M., van der Velden, J. & Kuster, D. W. D. Circ Res 133, 387-399 (2023).

Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease. Ziegler, K. A., Ahles, A., Dueck, A., Esfandyari, D., Pichler, P., Weber, K., Kotschi, S., Bartelt, A., Sinicina, I., Graw, M., Leonhardt, H., Weckbach, L. T., Massberg, S., Schifferer, M., Simons, M., Hoeher, L., Luo, J., Erturk, A., Schiattarella, G. G., Sassi, Y., Misgeld, T. & Engelhardt, S. Science 381, 285-290 (2023).

Higher gestational weight gain delays wound healing and reduces expression of long non-coding RNA KLRK1-AS1 in neonatal endothelial progenitor cells. Weiss, E., Schrufer, A., Tocantins, C., Diniz, M. S., Novakovic, B., van Bergen, A. S., Kulovic-Sissawo, A., Saffery, R., Boon, R. A. & Hiden, U. J Physiol 601, 3961-3974 (2023).

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The German CaRe high registry for familial hypercholesterolemia - Sex differences, treatment strategies, and target value attainment. Marz, W., Schmidt, N., An Haack, I., Dressel, A., Grammer, T. B., Kleber, M. E., Baessler, A., Beil, F. U., Gouni-Berthold, I., Julius, U., Kassner, U., Katzmann, J. L., Klose, G., Konig, C., Koenig, W., Koschker, A. C., Laufs, U., Merkel, M., Otte, B., Parhofer, K. G., Hengstenberg, W., Schunkert, H., Stach-Jablonski, K., Steinhagen-Thiessen, E., Olivier, C. B., Hahmann, H., Krzossok, S., Vogt, A., Muller-Wieland, D. & Schatz, U. Atheroscler Plus 53, 6-15 (2023).

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Systemic deletion of DMD exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking DMD exon 52. Stirm, M., Shashikadze, B., Blutke, A., Kemter, E., Lange, A., Stockl, J. B., Jaudas, F., Laane, L., Kurome, M., Kessler, B., Zakhartchenko, V., Bahr, A., Klymiuk, N., Nagashima, H., Walter, M. C., Wurst, W., Kupatt, C., Frohlich, T. & Wolf, E. Proc Natl Acad Sci U S A 120, e2301250120 (2023).

New Chapter in the PCSK9 Book: Oral Inhibition of PCSK9 Binding to the LDL Receptor With a Macrocyclic Peptide. Landmesser, U. & Makhmudova, U. Circulation 148, 159-161 (2023).

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Challenges in the evaluation of Covid-19 related cardiac alterations early after recovery from acute infection associated with severe lung involvement : Letter to the editor regarding the article "Paradoxical increase in left atrial strains early after Covid-19 infection, a result of comprehensive recovery phase four-chamber strains study", by Samiei N. et al. Int J cardiovasc imaging. 2023 May 10:1-11. Dandel, M. Int J Cardiovasc Imaging 39, 1871-1872 (2023).

Severe pulmonary valve insufficiency caused by transjugular cannulation of pulmonary artery for right ventricular assist device: diagnosis and surgical solution-a case report. Wert, L., Lanmuller, P., Ott, S., Mulzer, J., Starck, C. T., Falk, V. & Potapov, E. V. J Surg Case Rep 2023, rjad389 (2023).

Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling. Pontarollo, G., Kollar, B., Mann, A., Khuu, M. P., Kiouptsi, K., Bayer, F., Brandao, I., Zinina, V. V., Hahlbrock, J., Malinarich, F., Mimmler, M., Bhushan, S., Marini, F., Ruf, W., Belheouane, M., Baines, J. F., Endres, K., Reba, S. M., Raker, V. K., Deppermann, C., Welsch, C., Bosmann, M., Soshnikova, N., Chassaing, B., Bergentall, M., Sommer, F., Backhed, F. & Reinhardt, C. Nat Metab 5, 1174-1187 (2023).

Alterations in the hepatocyte epigenetic landscape in steatosis. Maji, R. K., Czepukojc, B., Scherer, M., Tierling, S., Cadenas, C., Gianmoena, K., Gasparoni, N., Nordstrom, K., Gasparoni, G., Laggai, S., Yang, X., Sinha, A., Ebert, P., Falk-Paulsen, M., Kinkley, S., Hoppstadter, J., Chung, H. R., Rosenstiel, P., Hengstler, J. G., Walter, J., Schulz, M. H., Kessler, S. M. & Kiemer, A. K. Epigenetics Chromatin 16, 30 (2023).

Incidence of atrial and ventricular arrhythmias in obese patients with heart failure with reduced ejection fraction treated with sacubitril/valsartan. Abumayyaleh, M., Demmer, J., Krack, C., Pilsinger, C., El-Battrawy, I., Aweimer, A., Lang, S., Mugge, A. & Akin, I. Diabetes Obes Metab 25, 2999-3011 (2023).

Vicious Twins: RyR2 Dysfunction and Structural Remodeling. Voigt, N., Seibertz, F. & Fakuade, F. E. Circ Res 133, 193-195 (2023).

Practical guidance to reduce radiation exposure in electrophysiology applying ultra low-dose protocols: a European Heart Rhythm Association review. Sommer, P., Sciacca, V., Anselmino, M., Tilz, R., Bourier, F., Lehrmann, H. & Bulava, A. Europace 25 (2023).

Initial therapeutic anticoagulation with rivaroxaban compared to prophylactic therapy with heparins in moderate to severe COVID-19: results of the COVID-PREVENT randomized controlled trial. Rauch-Krohnert, U., Puccini, M., Placzek, M., Beyer-Westendorf, J., Jakobs, K., Friebel, J., Hein, S., Seidel, M., Pieske, B., Massberg, S., Witzenrath, M., Zeiher, A., Friede, T., Anker, S. D. & Landmesser, U. Clin Res Cardiol 112, 1620-1638 (2023).

Proteomic profiling of longitudinal changes in kidney function among middle-aged and older men and women: the KORA S4/F4/FF4 study. Lin, J. S., Nano, J., Petrera, A., Hauck, S. M., Zeller, T., Koenig, W., Muller, C. L., Peters, A. & Thorand, B. BMC Med 21, 245 (2023).

Current practice and attitudes of stroke physicians towards rhythm-control therapy for stroke prevention: results of an international survey. Jensen, M., Al-Shahi Salman, R., Ng, G. A., van der Worp, H. B., Loh, P., Campbell, B. C. V., Kalman, J. M., Hill, M. D., Sposato, L. A., Andrade, J. G., Metzner, A., Kirchhof, P. & Thomalla, G. Neurol Res Pract 5, 29 (2023).

Direct oral anticoagulants versus vitamin K antagonist after transcatheter aortic valve implantation. Hohmann, C., Pfister, R., Frerker, C., Beckmann, A., Walther, T., Bleiziffer, S., Ensminger, S., Bekeredjian, R., Seiffert, M., Sinning, J. M., Mollmann, H., Beyersdorf, F., Baldus, S., Boning, A., Herrmann, E., Balaban, U., Kuhn, E. & Board, G. E. Heart 109, 1706-1713 (2023).

Incidence of hypoxic hepatitis in patients with cardiogenic shock and association with mortality. Beer, B. N., Besch, L., Weimann, J., Surendra, K., Roedl, K., Grensemann, J., Sundermeyer, J., Dettling, A., Kluge, S., Kirchhof, P., Blankenberg, S., Scherer, C. & Schrage, B. Eur Heart J Acute Cardiovasc Care 12, 663-670 (2023).

Understanding Who Responds to M-TEER in Heart Failure With SMR: Malnutrition Does Not Preclude Benefit. Anker, M. S., von Haehling, S. & Landmesser, U. J Am Coll Cardiol 82, 139-141 (2023).

Heyde syndrome: treat aortic valve disease to stop gastrointestinal bleeding? Waldschmidt, L. & Seiffert, M. Eur Heart J (2023).

The impact of obesity on cardiovascular and kidney outcomes in patients with chronic kidney disease and type 2 diabetes treated with finerenone: Post hoc analysis of the FIDELITY study. Rossing, P., Anker, S. D., Filippatos, G., Pitt, B., Ruilope, L. M., Billings, L. K., Green, J. B., Koya, D., Mosenzon, O., Pantalone, K. M., Ahlers, C., Lage, A., Lawatscheck, R., Scalise, A. & Bakris, G. L. Diabetes Obes Metab 25, 2989-2998 (2023).

Quality of life after pediatric cancer: comparison of long-term childhood cancer survivors' quality of life with a representative general population sample and associations with physical health and risk indicators. Ernst, M., Hinz, A., Brahler, E., Merzenich, H., Faber, J., Wild, P. S. & Beutel, M. E. Health Qual Life Outcomes 21, 65 (2023).

Has genetic disposition implications for treatment decisions in atrial fibrillation? Bourier, F. & Schunkert, H. Cardiovasc Res (2023).

PEPseq quantifies transcriptome-wide changes in protein occupancy and reveals selective translational repression after translational stress. Trendel, J., Boileau, E., Jochem, M., Dieterich, C. & Krijgsveld, J. Nucleic Acids Res (2023).

Worldwide variation in cardiovascular magnetic resonance practice models. Sierra-Galan, L. M., Estrada-Lopez, E. E. S., Ferrari, V. A., Raman, S. V., Ferreira, V. M., Raj, V., Joseph, E., Schulz-Menger, J., Chan, C. W. S., Chen, S. S. M., Cheng, Y., De Lara Fernandez, J., Terashima, M. & Albert, T. S. E. J Cardiovasc Magn Reson 25, 38 (2023).

Coronary microevaginations characterize culprit plaques and their inflammatory microenvironment in a subtype of acute coronary syndrome with intact fibrous cap: results from the prospective translational OPTICO-ACS study. Seppelt, C., Abdelwahed, Y. S., Meteva, D., Nelles, G., Stahli, B. E., Erbay, A., Krankel, N., Sieronski, L., Skurk, C., Haghikia, A., Sinning, D., Dreger, H., Knebel, F., Trippel, T. D., Krisper, M., Gerhardt, T., Rai, H., Klotsche, J., Joner, M., Landmesser, U. & Leistner, D. M. Eur Heart J Cardiovasc Imaging (2023).

Effect of bariatric surgery on cardio-psycho-metabolic outcomes in severe obesity: A randomized controlled trial. Koschker, A. C., Warrings, B., Morbach, C., Seyfried, F., Jung, P., Dischinger, U., Edelmann, F., Herrmann, M. J., Stier, C., Frantz, S., Malzahn, U., Stork, S., Fassnacht, M. & group, W. A. S. s. Metabolism147, 155655 (2023).

Sex-related differences in outcome after left atrial appendage occlusion: Insights from Europe and the EWOLUTION registry. Paitazoglou, C., Eitel, I., Stiermaier, T., Ince, H., Kische, S., Pokushalov, E., Schmitz, T., Schmidt, B., Gori, T., Meincke, F., Vireca, E., Wohlmuth, P., Lucas, B., Bergmann, M. W. & Investigators, E. Catheter Cardiovasc Interv (2023).

E-Health intervention for subthreshold depression: Reach and two-year effects of a randomized controlled trial. Guertler, D., Krause, K., Moehring, A., Bischof, G., Batra, A., Freyer-Adam, J., Ulbricht, S., Rumpf, H. J., Wurm, S., Cuijpers, P., Lucht, M., John, U. & Meyer, C. J Affect Disord 339, 33-42 (2023).


Paper of the Month

Cardiomuscular Biomarkers in the Diagnosis and Prognostication of Immune Checkpoint Inhibitor Myocarditis. Lehmann LH., Heckmann MB., Bailly G., Finke D., Procureur A., Power JR., Stein F., Bretagne M., Ederhy S., Fenioux C., Hamwy O., Funck-Brentano E., Romano E., Pieroni L., Münster JP., Allenbach Y., Anquetil C., Leonard-Louis S., Palaskas NL., Hayek SS., Katus HA., Giannitsis E., Frey N., Kaya Z., Moslehi J., Prifti E., Salem JE. Circulation. 148, 473-486, (2023).

The non-steroidal mineralocorticoid receptor antagonist finerenone and heart failure with preserved ejection fraction. Kintscher, U. & Edelmann, F. Cardiovasc Diabetol 22, 162 (2023).

Characterizing alternative splicing effects on protein interaction networks with LINDA. Gjerga, E., Naarmann-de Vries, I. S. & Dieterich, C. Bioinformatics 39, i458-i464 (2023).

Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project. Di Castelnuovo, A., Bonaccio, M., Costanzo, S., McElduff, P., Linneberg, A., Salomaa, V., Mannisto, S., Ferrieres, J., Dallongeville, J., Thorand, B., Brenner, H., Ferrario, M., Veronesi, G., Tamosiunas, A., Grimsgaard, S., Drygas, W., Malyutina, S., Soderberg, S., Nordendahl, M., Kee, F., Grassi, G., Dabboura, S., Borchini, R., Westermann, D., Schrage, B., Zeller, T., Kuulasmaa, K., Blankenberg, S., Donati, M. B., Iacoviello, L., Investigators, M. S. & de Gaetano, G. Eur J Epidemiol 38, 869-881 (2023).

Cardiovascular disease biomarkers derived from circulating cell-free DNA methylation. Cuadrat, R. R. C., Kratzer, A., Arnal, H. G., Rathgeber, A. C., Wreczycka, K., Blume, A., Gunduz, I. B., Ebenal, V., Mauno, T., Osberg, B., Moobed, M., Hartung, J., Jakobs, K., Seppelt, C., Meteva, D., Haghikia, A., Leistner, D. M., Landmesser, U. & Akalin, A. NAR Genom Bioinform 5, lqad061 (2023).

Decreased level of serum NT-proCNP associates with disease severity in COVID-19. Bojti, I., Przewosnik, A. S., Luxenburger, H., Hofmann, M., Neumann-Haefelin, C., Esser, J. S., Siegel, P. M., Maier, A., Kovacs, S. B., Kardos, L., Csanadi, Z., Rieder, M., Duerschmied, D., Lother, A., Bode, C., Szabo, G. T. & Czuriga, D. Respir Res 24, 174 (2023).

Impact of chronic kidney disease and diabetes on clinical outcomes in women undergoing PCI. Spirito, A., Itchhaporia, D., Sartori, S., Camenzind, E., Chieffo, A., Dangas, G. D., Galatius, S., Jeger, R. V., Kandzari, D. E., Kastrati, A., Kim, H. S., Kimura, T., Leon, M. B., Mehta, L. S., Mikhail, G. W., Morice, M. C., Nicolas, J., Pileggi, B., Serruys, P. W., Smits, P. C., Steg, P. G., Stone, G. W., Valgimigli, M., Vogel, B., von Birgelen, C., Weisz, G., Wijns, W., Windecker, S. & Mehran, R. EuroIntervention (2023).

Toll-like receptor 2, hyaluronan, and neutrophils play a key role in plaque erosion: the OPTICO-ACS study. Meteva, D., Vinci, R., Seppelt, C., Abdelwahed, Y. S., Pedicino, D., Nelles, G., Skurk, C., Haghikia, A., Rauch-Krohnert, U., Gerhardt, T., Straessler, E., Zhao, Y., Golla, F., Joner, M., Rai, H., Kratzer, A., Arnal, H. G., Liuzzo, G., Klotsche, J., Crea, F., Landmesser, U., Leistner, D. M. & Krankel, N. Eur Heart J (2023).

The importance of microvascular inflammation in ageing and age-related diseases: a position paper from the ESH working group on small arteries, section of microvascular inflammation. Mengozzi, A., de Ciuceis, C., Dell'oro, R., Georgiopoulos, G., Lazaridis, A., Nosalski, R., Pavlidis, G., Tual-Chalot, S., Agabiti-Rosei, C., Anyfanti, P., Camargo, L. L., Dabrowska, E., Quarti-Trevano, F., Hellmann, M., Masi, S., Mavraganis, G., Montezano, A. C., Rios, F. J., Winklewski, P. J., Wolf, J., Costantino, S., Gkaliagkousi, E., Grassi, G., Guzik, T. J., Ikonomidis, I., Narkiewicz, K., Paneni, F., Rizzoni, D., Stamatelopoulos, K., Stellos, K., Taddei, S., Touyz, R. M., Triantafyllou, A. & Virdis, A. J Hypertens (2023).

Culprit plaque morphology determines inflammatory risk and clinical outcomes in acute coronary syndrome. Gerhardt, T., Seppelt, C., Abdelwahed, Y. S., Meteva, D., Wolfram, C., Stapmanns, P., Erbay, A., Zanders, L., Nelles, G., Musfeld, J., Sieronski, L., Stahli, B. E., Montone, R. A., Vergallo, R., Haghikia, A., Skurk, C., Knebel, F., Dreger, H., Trippel, T. D., Rai, H., Joner, M., Klotsche, J., Libby, P., Crea, F., Krankel, N., Landmesser, U., Leistner, D. M. & group, O.-A. s. Eur Heart J (2023).

Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo. Varma, E., Burghaus, J., Schwarzl, T., Sekaran, T., Gupta, P., Gorska, A. A., Hofmann, C., Stroh, C., Jurgensen, L., Kamuf-Schenk, V., Li, X., Medert, R., Leuschner, F., Kmietczyk, V., Freichel, M., Katus, H. A., Hentze, M. W., Frey, N. & Volkers, M. Basic Res Cardiol 118, 25 (2023).

Comments on the myPACE Randomized Clinical Trial. Rodolico, D. & Schiattarella, G. G. JAMA Cardiol(2023).

Subannular repair in secondary mitral regurgitation with restricted leaflet motion during systole. Pausch, J., Harmel, E., Reichenspurner, H., Kempfert, J., Kuntze, T., Owais, T., Holubec, T., Walther, T., Krane, M., Vitanova, K., Borger, M. A., Eden, M., Hachaturyan, V., Bramlage, P., Falk, V. & Girdauskas, E. Heart 109, 1394-1400 (2023).

Cardiovascular health-related quality of life in cancer: a prospective study comparing the ESC HeartQoL and EORTC QLQ-C30 questionnaire. Anker, M. S., Potthoff, S. K., Lena, A., Porthun, J., Hadzibegovic, S., Evertz, R., Denecke, C., Frohlich, A. K., Sonntag, F., Regitz-Zagrosek, V., Rosen, S. D., Lyon, A. R., Luscher, T. F., Spertus, J. A., Anker, S. D., Karakas, M., Bullinger, L., Keller, U., Landmesser, U., Butler, J. & von Haehling, S. Eur J Heart Fail (2023).

Is telemonitoring for heart failure ready after a journey longer than two decades? Koehler, F. & Hindricks, G. Eur Heart J (2023).

Remote patient management of heart failure across the ejection fraction spectrum: A prespecified analysis of the TIM-HF2 trial. Kerwagen, F., Koehler, K., Vettorazzi, E., Stangl, V., Koehler, M., Halle, M., Koehler, F. & Stork, S. Eur J Heart Fail (2023).

Sex and age differences in AMPK phosphorylation, mitochondrial homeostasis, and inflammation in hearts from inflammatory cardiomyopathy patients. Barcena, M. L., Tonini, G., Haritonow, N., Breiter, P., Milting, H., Baczko, I., Muller-Werdan, U., Ladilov, Y. & Regitz-Zagrosek, V. Aging Cell, e13894 (2023).

Prevalence, clinical characteristics and outcomes of heart failure patients with or without isolated or combined mitral and tricuspid regurgitation: insight from the ESC-HFA EORP Heart Failure Long-Term Registry. Adamo, M., Chioncel, O., Benson, L., Shahim, B., Crespo-Leiro, M. G., Anker, S. D., Coats, A. J. S., Filippatos, G., Lainscak, M., McDonagh, T., Mebazaa, A., Piepoli, M. F., Rosano, G. M. C., Ruschitzka, F., Savarese, G., Seferovic, P., Shahim, A., Popescu, B. A., Iung, B., Volterrani, M., Maggioni, A. P., Metra, M. & Lund, L. H. Eur J Heart Fail (2023).

Patient motivation and preferences in changing co-occurring health risk behaviors in general hospital patients. Spielmann, M., Krolo-Wicovsky, F., Tiede, A., Krause, K., Baumann, S., Siewert-Markus, U., John, U. & Freyer-Adam, J. Patient Educ Couns 114, 107841 (2023).  

Identification of a novel redox switch between metabolism and cardiac function using HyPer power. Morawietz, H. Pflugers Arch (2023).

Validation of myeloproliferative neoplasms associated risk factor RDW as predictor of thromboembolic complications in healthy individuals: analysis on 6849 participants of the SHIP-study. Manz, K., Bahr, J., Ittermann, T., Dohner, K., Koschmieder, S., Brummendorf, T. H., Griesshammer, M., Nauck, M., Volzke, H. & Heidel, F. H. Leukemia (2023).

Enhanced diagnostic workup increases pathological findings in patients with acute ischaemic stroke: results of the prospective HEBRAS study. Hellwig, S., Krause, T., Scheitz, J. F., Herm, J., Grittner, U., Jauert, N., Fiebach, J. B., Kasner, M., Doehner, W., Endres, M., Wachter, R., Elgeti, T., Nolte, C. H. & Haeusler, K. G. Stroke Vasc Neurol (2023).

Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans. Guo, L., Salian, S., Xue, J. Y., Rath, N., Rousseau, J., Kim, H., Ehresmann, S., Moosa, S., Nakagawa, N., Kuroda, H., Clayton-Smith, J., Wang, J., Wang, Z., Banka, S., Jackson, A., Zhang, Y. M., Wei, Z. J., Huning, I., Brunet, T., Ohashi, H., Thomas, M. F., Bupp, C., Miyake, N., Matsumoto, N., Mendoza-Londono, R., Costain, G., Hahn, G., Di Donato, N., Yigit, G., Yamada, T., Nishimura, G., Ansel, K. M., Wollnik, B., Hrabe de Angelis, M., Megarbane, A., Rosenfeld, J. A., Heissmeyer, V., Ikegawa, S. & Campeau, P. M. Am J Hum Genet 110, 1068-1085 (2023).

Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids. Rybak-Wolf, A., Wyler, E., Pentimalli, T. M., Legnini, I., Oliveras Martinez, A., Glazar, P., Loewa, A., Kim, S. J., Kaufer, B. B., Woehler, A., Landthaler, M. & Rajewsky, N. Nat Microbiol (2023).

(V)apercu on the harm of nicotine e-cigarettes. Kuebler, W. M. Eur Respir J 61 (2023).

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy. Grosch, M., Schraft, L., Chan, A., Kuchenhoff, L., Rapti, K., Ferreira, A. M., Kornienko, J., Li, S., Radke, M. H., Kramer, C., Clauder-Munster, S., Perlas, E., Backs, J., Gotthardt, M., Dieterich, C., van den Hoogenhof, M. M. G., Grimm, D. & Steinmetz, L. M. Nat Commun 14, 3714 (2023).

Incidence and predictors of hemodynamic compromise due to high-grade AV block after TAVI. Weferling, M., Lan Cheong Wah, S., Fischer-Rasokat, U., Hain, A., Renker, M., Charitos, E. I., Liebetrau, C., Treiber, J., Choi, Y. H., Hamm, C. W. & Kim, W. K. Front Cardiovasc Med 10, 1161871 (2023).

Adhesion of human pathogenic bacteria to endothelial cells is facilitated by fibronectin interaction. Vaca, D. J., Frenzel, F., Ballhorn, W., Torres, S. G., Leisegang, M. S., Gunther, S., Bender, D., Kraiczy, P., Gottig, S. & Kempf, V. A. J. Microbes Infect, 105172 (2023).

Effect of SGLT2 Inhibitors on Cardiovascular Outcomes Across Various Patient Populations. Usman, M. S., Siddiqi, T. J., Anker, S. D., Bakris, G. L., Bhatt, D. L., Filippatos, G., Fonarow, G. C., Greene, S. J., Januzzi, J. L., Jr., Khan, M. S., Kosiborod, M. N., McGuire, D. K., Pina, I. L., Rosenstock, J., Vaduganathan, M., Verma, S., Zieroth, S. & Butler, J. J Am Coll Cardiol 81, 2377-2387 (2023).

The influence of atrial high-rate episodes on stroke and cardiovascular death: an update. Toennis, T., Bertaglia, E., Brandes, A., Dichtl, W., Fluschnik, N., de Groot, J. R., Marijon, E., Mont, L., Lundqvist, C. B., Cabanelas, N., Dan, G. A., Lubinski, A., Merkely, B., Rajappan, K., Sarkozy, A., Velchev, V., Wichterle, D. & Kirchhof, P. Europace 25 (2023).

Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues. Nakhaei-Rad, S., Haghighi, F., Bazgir, F., Dahlmann, J., Busley, A. V., Buchholzer, M., Kleemann, K., Schanzer, A., Borchardt, A., Hahn, A., Kotter, S., Schanze, D., Anand, R., Funk, F., Kronenbitter, A. V., Scheller, J., Piekorz, R. P., Reichert, A. S., Volleth, M., Wolf, M. J., Cirstea, I. C., Gelb, B. D., Tartaglia, M., Schmitt, J. P., Kruger, M., Kutschka, I., Cyganek, L., Zenker, M., Kensah, G. & Ahmadian, M. R. Commun Biol 6, 657 (2023).

Good rhythm control without haste: atrial fibrillation ablation remains effective after a year of waiting. Metzner, A. & Kirchhof, P. Eur Heart J (2023).

A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals. Lazaro, J., Costanzo, M., Sanaki-Matsumiya, M., Girardot, C., Hayashi, M., Hayashi, K., Diecke, S., Hildebrandt, T. B., Lazzari, G., Wu, J., Petkov, S., Behr, R., Trivedi, V., Matsuda, M. & Ebisuya, M. Cell Stem Cell (2023).

Come, Sweet Death: Why Endothelial Cells Die in Fructose. Kuebler, W. M. Am J Respir Cell Mol Biol 69, 247-249 (2023).

Fibin regulates cardiomyocyte hypertrophy and causes protein-aggregate-associated cardiomyopathy in vivo. Petersen, M., Schmiedel, N., Dierck, F., Hille, S., Remes, A., Senger, F., Schmidt, I., Lullmann-Rauch, R., Muller, O. J., Frank, D., Rangrez, A. Y., Frey, N. & Kuhn, C. Front Mol Biosci 10, 1169658 (2023).

Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality. Nemet, I., Li, X. S., Haghikia, A., Li, L., Wilcox, J., Romano, K. A., Buffa, J. A., Witkowski, M., Demuth, I., Konig, M., Steinhagen-Thiessen, E., Backhed, F., Fischbach, M. A., Tang, W. H. W., Landmesser, U. & Hazen, S. L. Eur Heart J (2023).

Towards a Precise NMR Quantification of Acute Phase Inflammation Proteins from Human Serum. Mallagaray, A., Rudolph, L., Lindloge, M., Molbitz, J., Thomsen, H., Schmelter, F., Alhabash, M. W., Abdullah, M. R., Saraei, R., Ehlers, M., Graf, T., Sina, C., Petersmann, A., Nauck, M. & Gunther, U. L. Angew Chem Int Ed Engl 62, e202306154 (2023).

Diversity of Ganglion Cell Responses to Saccade-Like Image Shifts in the Primate Retina. Kruppel, S., Khani, M. H., Karamanlis, D., Erol, Y. C., Zapp, S. J., Mietsch, M., Protti, D. A., Rozenblit, F. & Gollisch, T. J Neurosci 43, 5319-5339 (2023).

Sex differences in clinical characteristics and outcomes in patients undergoing heart transplantation. Kondziella, C., Fluschnik, N., Weimann, J., Schrage, B., Becher, P. M., Memenga, F., Bernhardt, A. M., Blankenberg, S., Reichenspurner, H., Kirchhof, P., Schnabel, R. B. & Magnussen, C. ESC Heart Fail (2023).

Pulmonary valve reconstruction for acquired pulmonary regurgitation in patients with treated congenital heart disease. Jussli-Melchers, J., Hansen, J. H., Scheewe, J., Attmann, T., Eide, M., Logoteta, J., Dutschke, P., Salehi Ravesh, M., Uebing, A. & Voges, I. Interdiscip Cardiovasc Thorac Surg (2023).

Cardio-hepatic syndrome in patients undergoing transcatheter aortic valve replacement. Stolz, L., Kirchner, M., Steffen, J., Doldi, P. M., Braun, D., Weckbach, L. T., Stocker, T. J., Low, K., Fischer, J., Haum, M., Theiss, H. D., Rizas, K., Orban, M., Peterss, S., Nabauer, M., Massberg, S., Hausleiter, J. & Deseive, S. Clin Res Cardiol (2023).

Brown fat has a sweet tooth. Lemmer, I. L. & Bartelt, A. Nat Metab 5, 1080-1081 (2023).

A new resorbable magnesium scaffold for de novo coronary lesions (DREAMS 3): one-year results of the BIOMAG-I first-in-human study. Haude, M., Wlodarczak, A., van der Schaaf, R. J., Torzewski, J., Ferdinande, B., Escaned, J., Iglesias, J. F., Bennett, J., Toth, G. G., Joner, M., Toelg, R., Wiemer, M., Olivecrano, G., Vermeersch, P., Garcia-Garcia, H. M. & Waksman, R. EuroIntervention 19, e414-e422 (2023).

Cardiac MRI-based right-to-left ventricular blood pool T2 relaxation times ratio correlates with exercise capacity in patients with chronic heart failure. Halfmann, M. C., Muller, L., von Henning, U., Kloeckner, R., Scholer, T., Kreitner, K. F., Duber, C., Wenzel, P., Varga-Szemes, A., Gobel, S. & Emrich, T. J Cardiovasc Magn Reson 25, 33 (2023).

Defining Strategies of Modulation of Antiplatelet Therapy in Patients With Coronary Artery Disease: A Consensus Document from the Academic Research Consortium. Capodanno, D., Mehran, R., Krucoff, M. W., Baber, U., Bhatt, D. L., Capranzano, P., Collet, J. P., Cuisset, T., De Luca, G., De Luca, L., Farb, A., Franchi, F., Gibson, C. M., Hahn, J. Y., Hong, M. K., James, S., Kastrati, A., Kimura, T., Lemos, P. A., Lopes, R. D., Magee, A., Matsumura, R., Mochizuki, S., O'Donoghue, M. L., Pereira, N. L., Rao, S. V., Rollini, F., Shirai, Y., Sibbing, D., Smits, P. C., Steg, P. G., Storey, R. F., Ten Berg, J., Valgimigli, M., Vranckx, P., Watanabe, H., Windecker, S., Serruys, P. W., Yeh, R. W., Morice, M. C. & Angiolillo, D. J. Circulation 147, 1933-1944 (2023).

Cardiomyocyte peroxisome proliferator-activated receptor alpha prevents septic cardiomyopathy via improving mitochondrial function. Zhou, X. X., Wang, X., Jiao, S. Y., Liu, Y., Shi, L., Xu, Q., Wang, J. J., Chen, Y. E., Zhang, Q., Song, Y. T., Wei, M., Yu, B. Q., Fielitz, J., Gonzalez, F. J., Du, J. & Qu, A. J. Acta Pharmacol Sin (2023).

Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts. Shi, M., Han, S., Klier, K., Fobo, G., Montrone, C., Yu, S., Harada, M., Henning, A. K., Friedrich, N., Bahls, M., Dorr, M., Nauck, M., Volzke, H., Homuth, G., Grabe, H. J., Prehn, C., Adamski, J., Suhre, K., Rathmann, W., Ruepp, A., Hertel, J., Peters, A. & Wang-Sattler, R.Cardiovasc Diabetol 22, 141 (2023).

Restored autophagy is protective against PAK3-induced cardiac dysfunction. Ruiz-Velasco, A., Raja, R., Chen, X., Ganenthiran, H., Kaur, N., Alatawi, N. H. O., Miller, J. M., Abouleisa, R. R. E., Ou, Q., Zhao, X., Fonseka, O., Wang, X., Hille, S. S., Frey, N., Wang, T., Mohamed, T. M. A., Muller, O. J., Cartwright, E. J. & Liu, W. iScience 26, 106970 (2023).

Novel bioresorbable scaffolds and lessons from recent history. Joner, M., Klosterman, G. & Byrne, R. A. EuroIntervention 19, 193-195 (2023).

Efficiently Quantifying DNA methylation for bulk- and single-cell bisulfite data. Fischer, J. & Schulz, M. Bioinformatics (2023).

Near-infrared Spectroscopy-Intravascular Ultrasound to Improve Assessment of Coronary Artery Disease Severity in Patients Referred for Transcatheter Aortic Valve Implantation (The IMPACTavi registry): Design and Rationale. Seguchi, M., Aytekin, A., Steiger, L., Nicol, P., Pellegrini, C., Rheude, T., Engel, L. C., Alvarez-Covarrubias, H., Xhepa, E., Mayr, N. P., Hadamitzky, M., Kastrati, A., Schunkert, H., Joner, M. & Lenz, T. Am Heart J (2023).

Association between a hospitalization for heart failure and the initiation/discontinuation of guideline-recommended treatments - An analysis from the Swedish heart failure registry. Schrage, B., Lund, L. H., Benson, L., Braunschweig, F., Ferreira, J. P., Dahlstrom, U., Metra, M., Rosano, G. M. & Savarese, G. Eur J Heart Fail (2023).

Cardiomuscular Biomarkers in the Diagnosis and Prognostication of Immune Checkpoint Inhibitor Myocarditis. Lehmann, L. H., Heckmann, M. B., Bailly, G., Finke, D., Procureur, A., Power, J. R., Stein, F., Bretagne, M., Ederhy, S., Fenioux, C., Hamwy, O., Funck-Brentano, E., Romano, E., Pieroni, L., Munster, J., Allenbach, Y., Anquetil, C., Leonard-Louis, S., Palaskas, N. L., Hayek, S. S., Katus, H. A., Giannitsis, E., Frey, N., Kaya, Z., Moslehi, J., Prifti, E., Salem, J. E. & International, I. C. I. M. R. C. Circulation (2023).

Effect of PCSK9 Inhibition on the Plasma Proteome: A SPIRE SubStudy. Kraaijenhof, J. M., Opstal, T. S. J., Cornel, J. H., Gill, D., Hovingh, G. K., Catapano, A. L., Koenig, W., Ridker, P. M., Stroes, E. S. G. & Nurmohamed, N. S. Arterioscler Thromb Vasc Biol (2023).

Ythdf2 regulates cardiac remodeling through its mRNA target transcripts. Kmietczyk, V., Oelschlager, J., Gupta, P., Varma, E., Hartl, S., Furkel, J., Konstandin, M., Marx, A., Loewenthal, Z., Kamuf-Schenk, V., Jurgensen, L., Stroh, C., Gorska, A., Martin-Garrido, A., Heineke, J., Jakobi, T., Frey, N. & Volkers, M. J Mol Cell Cardiol 181, 57-66 (2023).

Hand grip strength in patients with advanced cancer: A prospective study. Hadzibegovic, S., Porthun, J., Lena, A., Weinlander, P., Luck, L. C., Potthoff, S. K., Rosnick, L., Frohlich, A. K., Ramer, L. V., Sonntag, F., Wilkenshoff, U., Ahn, J., Keller, U., Bullinger, L., Mahabadi, A. A., Totzeck, M., Rassaf, T., von Haehling, S., Coats, A. J. S., Anker, S. D., Roeland, E. J., Landmesser, U. & Anker, M. S. J Cachexia Sarcopenia Muscle (2023).

Endocrine communication of endoplasmic reticulum stress. Gomez, A. M. & Bartelt, A. Bioessays 45, e2300093 (2023).

Myocardial injury in patients with acute ischemic stroke detected by cardiovascular magnetic resonance imaging. Blaszczyk, E., Hellwig, S., Saad, H., Ganeshan, R., Stengl, H., Nolte, C. H., Fiebach, J. B., Endres, M., Kuhnt, J., Groschel, J., Schulz-Menger, J. & Scheitz, J. F. Eur J Radiol 165, 110908 (2023).

Single-Cell Transcriptome Analysis of Peripheral Neutrophils From Patients With Idiopathic Pulmonary Arterial Hypertension. Zhang, R., Zhang, J., Zhang, Y. L., Gong, S. G., Zhao, Q. H., Wang, X. J., Zhao, J. Y., Jiang, R., Qiu, H. L., Li, H. T., He, J., Liu, S. F., Kuebler, W. M. & Wang, L. Hypertension (2023).

Much higher prevalence of keratoconus than announced results of the Gutenberg Health Study (GHS). Marx-Gross, S., Fiess, A., Munzel, T., Wild, P. S., Beutel, M. E., Schmidtmann, I., Lackner, K. J., Pfeiffer, N. & Schuster, A. K. Graefes Arch Clin Exp Ophthalmol, 1-7 (2023).

Predicted impact of atrial flow regulator on survival in heart failure with reduced and preserved ejection fraction. Lauder, L., Bergmann, M. W., Paitazoglou, C., Ozdemir, R., Iliadis, C., Bartunek, J., Lauten, A., Keller, T., Weber, S., Sievert, H., Anker, S. D. & Mahfoud, F. ESC Heart Fail (2023).

Left atrial disc device thrombosis after atrial defect closure with the Gore(R) Cardioform septal occluder: A case series. Kramer, P., Opgen-Rhein, B., Berger, F. & Nordmeyer, J. Catheter Cardiovasc Interv(2023).

An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes. Dai, Y., Ignatyeva, N., Xu, H., Wali, R., Toischer, K., Brandenburg, S., Lenz, C., Pronto, J., Fakuade, F. E., Sossalla, S., Zeisberg, E. M., Janshoff, A., Kutschka, I., Voigt, N., Urlaub, H., Rasmussen, T. B., Mogensen, J., Lehnart, S. E., Hasenfuss, G. & Ebert, A. Circ Res (2023).

Acute heart failure and valvular heart disease: A scientific statement of the Heart Failure Association, the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the European Society of Cardiology. Chioncel, O., Adamo, M., Nikolaou, M., Parissis, J., Mebazaa, A., Yilmaz, M. B., Hassager, C., Moura, B., Bauersachs, J., Harjola, V. P., Antohi, E. L., Ben-Gal, T., Collins, S. P., Iliescu, V. A., Abdelhamid, M., Celutkiene, J., Adamopoulos, S., Lund, L. H., Cicoira, M., Masip, J., Skouri, H., Gustafsson, F., Rakisheva, A., Ahrens, I., Mortara, A., Janowska, E. A., Almaghraby, A., Damman, K., Miro, O., Huber, K., Ristic, A., Hill, L., Mullens, W., Chieffo, A., Bartunek, J., Paolisso, P., Bayes-Genis, A., Anker, S. D., Price, S., Filippatos, G., Ruschitzka, F., Seferovic, P., Vidal-Perez, R., Vahanian, A., Metra, M., McDonagh, T. A., Barbato, E., Coats, A. J. S. & Rosano, G. M. C. Eur J Heart Fail (2023).

Modifiability of Composite Cardiovascular Risk Associated With Chronic Kidney Disease in Type 2 Diabetes With Finerenone. Agarwal, R., Pitt, B., Rossing, P., Anker, S. D., Filippatos, G., Ruilope, L. M., Kovesdy, C. P., Tuttle, K., Vaduganathan, M., Wanner, C., Bansilal, S., Gebel, M., Joseph, A., Lawatscheck, R. & Bakris, G. L. JAMA Cardiol (2023).

The 10 Commandments for Transaxillary TAVI. Sundermann, S. H., Dreger, H., Hinkov, H. & Kempfert, J.Innovations (Phila), 15569845231177055 (2023).

Completing the view - histologic insights from circular AAA specimen including 3D imaging : A methodologic approach towards histologic analysis of circumferential AAA samples. Menges, A. L., Nackenhorst, M., Muller, J. R., Engl, M. L., Hegenloh, R., Pelisek, J., Geibelt, E., Hofmann, A., Reeps, C., Biro, G., Eckstein, H. H., Zimmermann, A., Magee, D., Falk, M., Sachs, N. & Busch, A. Diagn Pathol 18, 73 (2023).  

How to treat left main coronary artery disease: the complementary lessons from trials and registries. McEntegart, M. & Gori, T. Eur Heart J (2023).

Blinded sample size recalculation in multiple composite population designs with normal data and baseline adjustments. Gera, R. G. & Friede, T. Biom J, e2000326 (2023).

The promise of optogenetic arrhythmia termination. Bruegmann, T. & Sacconi, L. J Intern Med 294, 248-250 (2023).

Circulating miRNAs in Hypertrophic Cardiomyopathy: A Long and Bumpy Road. van der Meer, P. & Van Linthout, S. Circ Heart Fail 16, e010694 (2023).

Novel oxidized LDL-based clinical markers in peritoneal dialysis patients for atherosclerosis risk assessment. Papadea, P., Kalaitzopoulou, E., Skipitari, M., Varemmenou, A., Papasotiriou, M., Papachristou, E., Goumenos, D., Grune, T. & Georgiou, C. D. Redox Biol 64, 102762 (2023).

Is the outcome of elective vs non-elective patients undergoing transcatheter aortic valve implantation different? Results of a single-centre, observational assessment of outcomes at a large university clinic. Wundram, S., Seoudy, H., Dummler, J. C., Ritter, L., Frank, J., Puehler, T., Lutter, G., Lutz, M., Saad, M., Bramlage, P., Sathananthan, J., Wood, D. A., Lauck, S. B., Frey, N. & Frank, D. BMC Cardiovasc Disord 23, 295 (2023).

CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms. Skryabin, E. B., De Jong, K. A., Subramanian, H., Bork, N. I., Froese, A., Skryabin, B. V. & Nikolaev, V. O. Cells 12 (2023).

Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients? Theobald, V., Grunig, E., Benjamin, N., Seyfarth, H. J., Halank, M., Schneider, M. A., Richtmann, S., Kazdal, D., Hinderhofer, K., Xanthouli, P., Egenlauf, B., Harutyunova, S., Hoeper, M. M., Jonigk, D., Sparla, R., Muckenthaler, M. U. & Eichstaedt, C. A. Pulm Circ 13, e12242 (2023).

Distinctive Paravalvular Jets of a Novel Self-Expanding Transcatheter Aortic Valve With a Unique Skirt Design. Romero Dorta, E., Mattig, I., Kosters, L., Sundermann, S. H., Spethmann, S., Stangl, K. & Dreger, H. JACC Cardiovasc Interv (2023).

The Heart and Artificial Intelligence-How Can We Improve Medicine Without Causing Harm. Reich, C. & Meder, B. Curr Heart Fail Rep, 1-9 (2023).

Bioprosthetic Valve Remodeling in Nonfracturable Surgical Valves: Impact on THV Expansion and Hydrodynamic Performance. Meier, D., Puehler, T., Lutter, G., Shen, C., Lai, A., Gill, H., Akodad, M., Tzimas, G., Chhatriwalla, A., Allen, K. B., Blanke, P., Payne, G. W., Wood, D. A., Leipsic, J. A., Webb, J. G., Sellers, S. L. & Sathananthan, J. JACC Cardiovasc Interv (2023).

mTORC1 inhibition impairs activation of the unfolded protein response and induces cell death during ER stress in cardiomyocytes. Hofmann, C., Lowenthal, Z., Aghajani, M., Kaufman, R. J., Katus, H. A., Frey, N., Glembotski, C. C., Volkers, M. & Doroudgar, S. Am J Physiol Heart Circ Physiol (2023).

Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture. Sun, J., Singh, P., Shami, A., Kluza, E., Pan, M., Djordjevic, D., Michaelsen, N. B., Kennback, C., van der Wel, N. N., Orho-Melander, M., Nilsson, J., Formentini, I., Conde-Knape, K., Lutgens, E., Edsfeldt, A. & Goncalves, I. J Am Coll Cardiol 81, 2213-2227 (2023).

Computed tomography-based pericoronary adipose tissue attenuation in patients undergoing TAVR: a novel method for risk assessment. Steyer, A., Mas-Peiro, S., Leistner, D. M., Puntmann, V. O., Nagel, E., Dey, D., Goeller, M., Koch, V., Booz, C., Vogl, T. J. & Martin, S. S. Front Cardiovasc Med 10, 1192093 (2023).

Takotsubo syndrome and cardiogenic shock: Authors' response. Santoro, F., Nunez Gil, I. J., Stiermaier, T., Eitel, I., Arcari, L. & Brunetti, N. D. Eur Heart J Open 3, oead054 (2023).

Motion-corrected model-based reconstruction for 2D myocardial T1 mapping. Kerkering, K. M., Schulz-Menger, J., Schaeffter, T. & Kolbitsch, C. Magn Reson Med (2023).

Intraocular Pressure and Its Relation to Climate Parameters-Results From the Gutenberg Health Study. Hartmann, A., Grabitz, S. D., Hoffmann, E. M., Wild, P. S., Schmidtmann, I., Lackner, K. J., Beutel, M. E., Munzel, T., Tuscher, O., Schattenberg, J. M., Pfeiffer, N. & Schuster, A. K. Invest Ophthalmol Vis Sci 64, 15 (2023).

Transaxillary implantation of a temporary microaxial left ventricular assist device in a patient with a rectangular kinked subclavian artery. Wert, L., Kempfert, J., Falk, V. & Potapov, E. V. Interdiscip Cardiovasc Thorac Surg 36 (2023).

Adipose tissue is associated with kidney function parameters. Mueller-Peltzer, K., von Kruchten, R., Lorbeer, R., Rospleszcz, S., Schulz, H., Peters, A., Bamberg, F., Schlett, C. L. & Mujaj, B. Sci Rep 13, 9151 (2023).

The role of acrolein for E-cigarette vapour condensate mediated activation of NADPH oxidase in cultured endothelial cells and macrophages. Kuntic, I., Kuntic, M., Oelze, M., Stamm, P., Karpi, A., Kleinert, H., Hahad, O., Munzel, T. & Daiber, A. Pflugers Arch 475, 807-821 (2023).

Radiosurgery for ventricular tachycardia (RAVENTA): interim analysis of a multicenter multiplatform feasibility trial. Krug, D., Zaman, A., Eidinger, L., Grehn, M., Boda-Heggemann, J., Rudic, B., Mehrhof, F., Boldt, L. H., Hohmann, S., Merten, R., Buergy, D., Fleckenstein, J., Kluge, A., Rogge, A., Both, M., Rades, D., Tilz, R. R., Olbrich, D., Konig, I. R., Siebert, F. A., Schweikard, A., Vonthein, R., Bonnemeier, H., Dunst, J. & Blanck, O. Strahlenther Onkol 199, 621-630 (2023).

Gender Differences and the Impact of Partnership and Children on Quality of Life During the COVID-19 Pandemic. Hettich-Damm, N., Petersen, J., Zahn, D., Baumkoetter, R., Wild, P. S., Muenzel, T., Schuster, A. K., Koenig, J., Lackner, K., Pfeiffer, N., Beutel, M. E. & Engwicht, E. Int J Public Health 68, 1605826 (2023).

Improvement of exercise and functional capacity and quality of life in patients with heart failure by iron therapy. Deichl, A. & Edelmann, F. Front Cardiovasc Med 10, 1025957 (2023).

Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study Group. Mezquita, A. J. V., Biavati, F., Falk, V., Alkadhi, H., Hajhosseiny, R., Maurovich-Horvat, P., Manka, R., Kozerke, S., Stuber, M., Derlin, T., Channon, K. M., Isgum, I., Coenen, A., Foellmer, B., Dey, D., Volleberg, R., Meinel, F. G., Dweck, M. R., Piek, J. J., van de Hoef, T., Landmesser, U., Guagliumi, G., Giannopoulos, A. A., Botnar, R. M., Khamis, R., Williams, M. C., Newby, D. E. & Dewey, M. Nat Rev Cardiol (2023).

Liver tests, cardiovascular outcomes and effects of empagliflozin in patients with heart failure and preserved ejection fraction: the EMPEROR-Preserved Trial. Bohm, M., Butler, J., Krawczyk, M., Mahfoud, F., Haring, B., Filippatos, G., Ferreira, J. P., Pocock, S. J., Brueckmann, M., Ofstad, A. P., Schuler, E., Wanner, C., Verma, S., Packer, M., Anker, S. D., Committees, E. M.-P. T. & Investigators. Eur J Heart Fail(2023).

The consequences of neglected confounding and interactions in mixed-effects meta-regression: An illustrative example. Knop, E. S., Pauly, M., Friede, T. & Welz, T. Res Synth Methods (2023).

Editorial: Special issue: "Impact of lifestyle und behavioral risk factors on endothelial function and vascular biology"-how lifestyle and behavioral risk factors affect the vasculature. Daiber, A., Hahad, O. & Munzel, T. Pflugers Arch 475, 777-781 (2023).

Trajectories of glycaemic traits exhibit sex-specific associations with hepatic iron and fat content: Results from the KORA-MRI study. Niedermayer, F., Su, Y., von Kruchten, R., Thorand, B., Peters, A., Rathmann, W., Roden, M., Schlett, C. L., Bamberg, F., Nattenmuller, J. & Rospleszcz, S. Liver Int (2023).

Preclinical Imaging of Cardiovascular Disesase. Nekolla, S. G., Rischpler, C. & Higuchi, T. Semin Nucl Med(2023).

Maternal haemodynamics in Hypertensive Disorders of Pregnancy under antihypertensive therapy (HyperDiP): study protocol for a prospective observational case-control study. Palmrich, P., Haase, N., Sugulle, M., Kalafat, E., Khalil, A. & Binder, J. BMJ Open 13, e065444 (2023).

Late-stage peptide labeling with near-infrared fluorogenic nitrobenzodiazoles by manganese-catalyzed C-H activation. Oyama, T., Mendive-Tapia, L., Cowell, V., Kopp, A., Vendrell, M. & Ackermann, L.Chem Sci 14, 5728-5733 (2023).

Development and validation of explainable machine learning models for risk of mortality in transcatheter aortic valve implantation: TAVI risk machine scores. Leha, A., Huber, C., Friede, T., Bauer, T., Beckmann, A., Bekeredjian, R., Bleiziffer, S., Herrmann, E., Mollmann, H., Walther, T., Beyersdorf, F., Hamm, C., Kunzi, A., Windecker, S., Stortecky, S., Kutschka, I., Hasenfuss, G., Ensminger, S., Frerker, C. & Seidler, T. Eur Heart J Digit Health 4, 225-235 (2023).

Association of genetic risk and outcomes in patients with atrial fibrillation: interactions with early rhythm control in the EAST-AFNET4 trial. Kany, S., Al-Taie, C., Roselli, C., Pirruccello, J. P., Borof, K., Reinbold, C., Suling, A., Krause, L., Reissmann, B., Schnabel, R. B., Zeller, T., Zapf, A., Wegscheider, K., Fabritz, L., Ellinor, P. T. & Kirchhof, P. Cardiovasc Res (2023).

Immature human engineered heart tissues engraft in a guinea pig chronic injury model. von Bibra, C., Shibamiya, A., Bahr, A., Geertz, B., Kohne, M., Stuedemann, T., Starbatty, J., Horneffer-van der Sluis, V., Klostermeier, U. C., Hornaschewitz, N., Li, X., Wolf, E., Klymiuk, N., Krane, M., Kupatt, C., Hiebl, B., Eschenhagen, T. & Weinberger, F. Dis Model Mech (2023).

Human pluripotent stem cell-based models of heart development and disease. Velichkova, G. & Dobreva, G. Cells Dev 175, 203857 (2023).

Extent of routine diagnostic cardiac work-up at certified German stroke units participating in the prospective MonDAFIS study. Olma, M. C., Tutuncu, S., Grittner, U., Kunze, C., Jawad-Ul-Qamar, M., Kirchhof, P., Rother, J., Thomalla, G., Veltkamp, R., Laufs, U., Nabavi, D. G., Heuschmann, P. U., Endres, M. & Haeusler, K. G. Neurol Res Pract 5, 21 (2023).

ncOrtho: efficient and reliable identification of miRNA orthologs. Langschied, F., Leisegang, M. S., Brandes, R. P. & Ebersberger, I. Nucleic Acids Res (2023).

Lazy Luna: Extendible software for multilevel reader comparison in cardiovascular magnetic resonance imaging. Hadler, T., Ammann, C., Wetzl, J., Viezzer, D., Groschel, J., Fenski, M., Abazi, E., Lange, S., Hennemuth, A. & Schulz-Menger, J. Comput Methods Programs Biomed 238, 107615 (2023).

Fear of COVID-19 disease and vaccination as predictors of vaccination status. Gilan, D., Birkenbach, M., Wossidlo, M., Sprengholz, P., Betsch, C., Hahad, O. & Lieb, K. Sci Rep 13, 8865 (2023).

Alternative splicing analysis benchmark with DICAST. Fenn, A., Tsoy, O., Faro, T., Rossler, F. L. M., Dietrich, A., Kersting, J., Louadi, Z., Lio, C. T., Volker, U., Baumbach, J., Kacprowski, T. & List, M. NAR Genom Bioinform 5, lqad044 (2023).

Is spontaneous echo contrast associated with device-related thrombus or embolic events after left atrial appendage occlusion? - Insights from the multicenter German LAARGE registry. Fastner, C., Muller, C., Brachmann, J., Lewalter, T., Akin, I., Sievert, H., Kaunicke, M., Zeymer, U., Hochadel, M., Schneider, S., Senges, J., Erkapic, D. & Weiss, C. J Interv Card Electrophysiol (2023).


Paper of the Month

The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Gatsiou A., Tual-Chalot S., Napoli M., Ortega-Gomez A., Regen T., Badolia R., Cesarini V., Garcia-Gonzalez C., Chevre R., Ciliberti G., Silvestre-Roig C., Martini M., Hoffmann J., Hamouche R., Visker JR., Diakos N., Wietelmann A., Silvestris DA., Georgiopoulos G., Moshfegh A., Schneider A., Chen W., Guenther S., Backs J., Kwak S., Selzman CH., Stamatelopoulos K., Rose-John S., Trautwein C., Spyridopoulos I., Braun T., Waisman A., Gallo A., Drakos SG., Dimmeler S., Sperandio M., Soehnlein O., Stellos K. Immunity. 56, 979-997, (2023).

Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor modulating factors. Nording, H. M., Baron, L., Sauter, M., Lubken, A., Rawish, E., Szepanowski, R. D., von Esebeck, J., Sun, Y., Emami, H., Meusel, M., Saraei, R., Schanze, N., Gorantla, S. P., von Bubnoff, N., Geisler, T., von Hundelshausen, P., Stellos, K., Marquardt, J., Sadik, C., Koehl, J., Duerschmied, D., Kleinschnitz, C. & Langer, H. F. Blood Adv (2023).

Large-scale microRNA functional high-throughput screening identifies miR-515-3p and miR-519e-3p as inducers of human cardiomyocyte proliferation. Renikunta, H. V., Lazarow, K., Gong, Y., Shukla, P. C., Nageswaran, V., Giral, H., Kratzer, A., Opitz, L., Engel, F. B., Haghikia, A., Costantino, S., Paneni, F., von Kries, J. P., Streckfuss-Bomeke, K., Landmesser, U. & Jakob, P. iScience 26, 106593 (2023).

Correction of a deleterious TBX5 mutation in an induced pluripotent stem cell line (DHMi004-A-1) using a completely plasmid-free CRISPR/Cas 9 approach. Lahm, H., Dzilic, E., Neb, I., Doppler, S. A., Schneider, S., Lange, R., Krane, M. & Dressen, M. Stem Cell Res 70, 103126 (2023).

Efficacy and safety of inclisiran in patients with cerebrovascular disease: ORION-9, ORION-10, and ORION-11. Koenig, W., Ray, K. K., Landmesser, U., Leiter, L. A., Schwartz, G. G., Wright, R. S., Conde, L. G., Han, J. & Raal, F. J. Am J Prev Cardiol 14, 100503 (2023).

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Benchmarking the Impact of Noise on Deep Learning-Based Classification of Atrial Fibrillation in 12-Lead ECG. Bender, T., Gemke, P., Idrobo-Avila, E., Dathe, H., Krefting, D. & Spicher, N. Stud Health Technol Inform 302, 977-981 (2023).

INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10. Zhang, W., Zhao, J., Deng, L., Ishimwe, N., Pauli, J., Wu, W., Shan, S., Kempf, W., Ballantyne, M. D., Kim, D., Lyu, Q., Bennett, M., Rodor, J., Turner, A. W., Lu, Y. W., Gao, P., Choi, M., Warthi, G., Kim, H. W., Barroso, M. M., Bryant, W. B., Miller, C. L., Weintraub, N. L., Maegdefessel, L., Miano, J. M., Baker, A. H. & Long, X. Circulation (2023).

Presence of Peripheral Artery Disease Is Associated With Increased Risk of Heart Failure Events: Insights From EMPEROR-Pooled. Verma, S., Dhingra, N. K., Bonaca, M. P., Butler, J., Anker, S. D., Ferreira, J. P., Filippatos, G., Januzzi, J. L., Lam, C. S. P., Sattar, N., Iwata, T., Nordaby, M., Brueckmann, M., Pocock, S. J., Packer, M., Committees, E. T. & Investigators. Arterioscler Thromb Vasc Biol 43, 1334-1337 (2023).

Safety and Effectiveness of Pulsed Field Ablation to Treat Atrial Fibrillation: One-Year Outcomes From the MANIFEST-PF Registry. Turagam, M. K., Neuzil, P., Schmidt, B., Reichlin, T., Neven, K., Metzner, A., Hansen, J., Blaauw, Y., Maury, P., Arentz, T., Sommer, P., Anic, A., Anselme, F., Boveda, S., Deneke, T., Willems, S., van der Voort, P., Tilz, R., Funasako, M., Scherr, D., Wakili, R., Steven, D., Kautzner, J., Vijgen, J., Jais, P., Petru, J., Chun, J., Roten, L., Futing, A., Lemoine, M. D., Ruwald, M., Mulder, B. A., Rollin, A., Lehrmann, H., Fink, T., Jurisic, Z., Chaumont, C., Adelino, R., Nentwich, K., Gunawardene, M., Ouss, A., Heeger, C. H., Manninger, M., Bohnen, J. E., Sultan, A., Peichl, P., Koopman, P., Derval, N., Kueffer, T., Rahe, G. & Reddy, V. Y. Circulation (2023).

Hemodynamic Assessment in Takotsubo Syndrome. Stiermaier, T., Reil, J. C., Sequeira, V., Rawish, E., Mezger, M., Patz, T., Paitazoglou, C., Schmidt, T., Frerker, C., Steendijk, P., Reil, G. H. & Eitel, I. J Am Coll Cardiol 81, 1979-1991 (2023).

Transcatheter Therapy for Tricuspid Regurgitation - First Act. Orban, M. & Massberg, S. N Engl J Med388, 1902-1903 (2023).

Duration of Surgery and Intraoperative Blood Pressure Management are Modifiable Risk Factors for Postoperative Neurocognitive Disorders Following Spine Surgery: Results of the Prospective CONFESS Study. Muller, J., Nowak, S., Weidemeier, M., Vogelgesang, A., Ruhnau, J., von Sarnowski, B., Saar, A., Veser, Y., Behr, F., Gross, S., Rathmann, E., Schmidt, S., Rehberg, S., Usichenko, T., Hahnenkamp, K., Ehler, J., Floel, A., Schroeder, H. W. S., Muller, J. U. & Fleischmann, R. Spine (Phila Pa 1976) (2023).

Transcatheter Mitral Valve Replacement versus Medical Therapy for Secondary Mitral Regurgitation: A Propensity Score-Matched Comparison. Ludwig, S., Conradi, L., Cohen, D. J., Coisne, A., Scotti, A., Abraham, W. T., Ben Ali, W., Zhou, Z., Li, Y., Kar, S., Duncan, A., Lim, D. S., Adamo, M., Redfors, B., Muller, D. W. M., Webb, J. G., Petronio, A. S., Ruge, H., Nickenig, G., Sondergaard, L., Adam, M., Regazzoli, D., Garatti, A., Schmidt, T., Andreas, M., Dahle, G., Walther, T., Kempfert, J., Tang, G. H., Redwood, S. R., Taramasso, M., Praz, F., Fam, N. P., Dumonteil, N., Obadia, J. F., von Bardeleben, R. S., Rudolph, T. K., Reardon, M. J., Metra, M., Denti, P., Mack, M. J., Hausleiter, J., Asch, F. M., Latib, A., Lindenfeld, J., Modine, T., Stone, G. W., Granada, J. F., Choice, M. I. & the, C. T. I. Circ Cardiovasc Interv (2023).

In-ovo echocardiography for application in cardiovascular research. Hegemann, N., Bintig, W., Perret, P. L., Rees, J., Viperino, A., Eickholt, B., Kuebler, W. M., Hopfner, M., Nitzsche, B. & Grune, J. Basic Res Cardiol 118, 19 (2023).

Corrigendum: Monocyte signature as a predictor of chronic lung disease in the preterm infant. Windhorst, A. C., Heydarian, M., Schwarz, M., Oak, P., Forster, K., Frankenberger, M., Gonzalez Rodriguez, E., Zhang, X., Ehrhardt, H., Hubener, C., Flemmer, A. W., Hossain, H., Stoeger, T., Schulz, C. & Hilgendorff, A.Front Immunol 14, 1209992 (2023).

Inflammaging aggravates stroke pathology. Schulz, C. & Massberg, S. Nat Immunol 24, 887-888 (2023).

Transcatheter Aortic Valve Replacement in Patients With Reduced Ejection Fraction and Nonsevere Aortic Stenosis. Ludwig, S., Schofer, N., Abdel-Wahab, M., Urena, M., Jean, G., Renker, M., Hamm, C. W., Thiele, H., Iung, B., Ooms, J. F., Wiessman, M., Mogensen, N. S. B., Longere, B., Perrin, N., Ben Ali, W., Coisne, A., Dahl, J. S., Van Mieghem, N. M., Kornowski, R., Kim, W. K. & Clavel, M. A. Circ Cardiovasc Interv 16, e012768 (2023).

[Smoking cessation in hospitalised patients - Initiate among inpatients, continue when outpatients - A Position Paper by the German Respiratory Society (DGP) Taskforce for Smoking Cessation]. Raspe, M., Bals, R., Bolukbas, S., Faber, G., Krabbe, B., Landmesser, U., Al Najem, S., Przibille, O., Raupach, T., Rupp, A., Rustler, C., Tuffman, A., Urlbauer, M., Voigtlander, T., Andreas, S., In Zusammenarbeit mit weiteren medizinischen Fachgesellschaften und Organisationen: Deutsche Gesellschaft fur Innere, M., Deutsche Gesellschaft fur Kardiologie - Herz- und, K., Deutsche Gesellschaft fur Angiologie - Gesellschaft fur, G., Deutsche Gesellschaft fur Hamatologie und Medizinische, O., Deutsche Gesellschaft fur, T., Bundesverband der Pneumologen, S.-u. B., Verband Pneumologischer, K., Deutsche, A., Deutsche, L. & Deutsche, H. Pneumologie 77, 341-349 (2023).

Mitigation of aircraft noise-induced vascular dysfunction and oxidative stress by exercise, fasting, and pharmacological alpha1AMPK activation: molecular proof of a protective key role of endothelial alpha1AMPK against environmental noise exposure. Kvandova, M., Rajlic, S., Stamm, P., Schmal, I., Mihalikova, D., Kuntic, M., Bayo Jimenez, M. T., Hahad, O., Kollarova, M., Ubbens, H., Strohm, L., Frenis, K., Duerr, G. D., Foretz, M., Viollet, B., Ruan, Y., Jiang, S., Tang, Q., Kleinert, H., Rapp, S., Gericke, A., Schulz, E., Oelze, M., Keaney, J. F., Daiber, A., Kroller-Schon, S., Jansen, T. & Munzel, T. Eur J Prev Cardiol(2023).

Cardiovascular comorbidity in psoriasis - psoriatic inflammation is more than just skin deep. Kommoss, K. S., Enk, A., Heikenwalder, M., Waisman, A., Karbach, S. & Wild, J. J Dtsch Dermatol Ges (2023).

Proportional Internal Work-a New Parameter of Exercise Testing in Study of Health in Pomerania (SHIP). Ittermann, T., Ewert, R., Habedank, D., Kaczmarek, S., Felix, S. B., Dorr, M., Stubbe, B. & Bahls, M. J Cardiopulm Rehabil Prev (2023).  

Thrombo-inflammation in Long COVID - the elusive key to post-infection sequelae? Nicolai, L., Kaiser, R. & Stark, K. J Thromb Haemost (2023).

Sites of transcription initiation drive mRNA isoform selection. Alfonso-Gonzalez, C., Legnini, I., Holec, S., Arrigoni, L., Ozbulut, H. C., Mateos, F., Koppstein, D., Rybak-Wolf, A., Bonisch, U., Rajewsky, N. & Hilgers, V. Cell (2023).

Six-months clinical and intracoronary imaging follow-up after reverse T and protrusion or double-kissing and crush stenting for the treatment of complex left main bifurcation lesions. Abouelnour, A. E., Olschewski, M., Makmur, G., Ullrich, H., Knorr, M., Ahoopai, M., Munzel, T. & Gori, T. Front Cardiovasc Med 10, 1153652 (2023).

Association of De Ritis Ratio with Prognosis in Patients with Coronary Artery Disease and Aminotransferase Activity within and outside the Healthy Values of Reference Range. Ndrepepa, G., Cassese, S., Scalamogna, M., Lahu, S., Aytekin, A., Xhepa, E., Schunkert, H. & Kastrati, A. J Clin Med 12(2023).

NT-proBNP Is a Predictor of Mortality in Adults with Pulmonary Arterial Hypertension Associated with Congenital Heart Disease. Maurer, S. J., Habdank, V., Horer, J., Ewert, P. & Tutarel, O. J Clin Med 12(2023).

Radiation Dose Reduction for Coronary Artery Calcium Scoring Using a Virtual Noniodine Algorithm on Photon-Counting Detector Computed-Tomography Phantom Data. Fink, N., Zsarnoczay, E., Schoepf, U. J., O'Doherty, J., Griffith, J. P., 3rd, Pinos, D., Tesche, C., Ricke, J., Willemink, M. J., Varga-Szemes, A. & Emrich, T. Diagnostics (Basel) 13 (2023).

Analysis of volume and topography of adipose tissue in the trunk: Results of MRI of 11,141 participants in the German National Cohort. Haueise, T., Schick, F., Stefan, N., Schlett, C. L., Weiss, J. B., Nattenmuller, J., Gobel-Gueniot, K., Norajitra, T., Nonnenmacher, T., Kauczor, H. U., Maier-Hein, K. H., Niendorf, T., Pischon, T., Jockel, K. H., Umutlu, L., Peters, A., Rospleszcz, S., Kroncke, T., Hosten, N., Volzke, H., Krist, L., Willich, S. N., Bamberg, F. & Machann, J. Sci Adv 9, eadd0433 (2023).

Comprehensive Characterization of Non-Cardiac Comorbidities in Acute Heart Failure- an analysis of ESC-HFA EORP Heart Failure Long-Term Registry. Chioncel, O., Benson, L., Crespo-Leiro, M. G., Anker, S. D., Coats, A. J. S., Filippatos, G., McDonagh, T., Margineanu, C., Mebazaa, A., Metra, M., Piepoli, M. F., Adamo, M., Rosano, G. M. C., Ruschitzka, F., Savarese, G., Seferovic, P., Volterrani, M., Ferrari, R., Maggioni, A. P. & Lund, L. H. Eur J Prev Cardiol (2023).

Targeting non-coding RNAs for novel treatment strategies in vascular diseases. Winter, H. & Maegdefessel, L. Eur Heart J (2023).  

The contribution of the exposome to the burden of cardiovascular disease. Munzel, T., Sorensen, M., Hahad, O., Nieuwenhuijsen, M. & Daiber, A. Nat Rev Cardiol (2023).

Alcohol and the vasculature: a love-hate relationship? Li, H. & Xia, N. Pflugers Arch 475, 867-875 (2023).

Efficacy of Empagliflozin in Patients With Heart Failure Across Kidney Risk Categories. Butler, J., Packer, M., Siddiqi, T. J., Bohm, M., Brueckmann, M., Januzzi, J. L., Verma, S., Gergei, I., Iwata, T., Wanner, C., Ferreira, J. P., Pocock, S. J., Filippatos, G., Anker, S. D. & Zannad, F. J Am Coll Cardiol 81, 1902-1914 (2023).

Prophylactic effect of angiotensin receptor blockers in children with genetic aortopathies: the early bird catches the worm. Olfe, J., Kanitz, J. J., Stark, V. C., Stute, F., von Kodolitsch, Y., Biermann, D., Huebler, M., Kozlik-Feldmann, R. & Mir, T. S. Clin Res Cardiol (2023).

Association of autoantibody levels with different stages of age-related macular degeneration (AMD): Results from the population-based Gutenberg Health Study (GHS). Korb, C. A., Lackner, K. J., Wolters, D., Schuster, A. K., Nickels, S., Beutgen, V. M., Munzel, T., Wild, P. S., Beutel, M. E., Schmidtmann, I., Pfeiffer, N. & Grus, F. H. Graefes Arch Clin Exp Ophthalmol (2023).  

Matrix metalloproteinases in coronary artery disease and myocardial infarction. Brauninger, H., Kruger, S., Bacmeister, L., Nystrom, A., Eyerich, K., Westermann, D. & Lindner, D. Basic Res Cardiol 118, 18 (2023).

Reversibility of Diffusion-Weighted Imaging Lesions in Patients With Ischemic Stroke in the WAKE-UP Trial. Scheldeman, L., Wouters, A., Bertels, J., Dupont, P., Cheng, B., Ebinger, M., Endres, M., Fiebach, J. B., Gerloff, C., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Thijs, V., Thomalla, G. & Lemmens, R. Stroke 54, 1560-1568 (2023).

Mental disorders and cardiovascular disease: not just an issue of older age. Herrmann-Lingen, C. Eur J Prev Cardiol (2023).

Rising and Falling High-Sensitivity Cardiac Troponin in Diagnostic Algorithms for Patients With Suspected Myocardial Infarction. Haller, P. M., Sorensen, N. A., Hartikainen, T. S., Gossling, A., Lehmacher, J., Toprak, B., Twerenbold, R., Richter, J., Banko, T., Korschid, S., Schmidt, J., Keller, T., Zeller, T., Blankenberg, S., Westermann, D. & Neumann, J. T. J Am Heart Assoc 12, e027166 (2023).

The power of large cohorts to improve cardiovascular risk prediction and prevention. Bahls, M. Eur J Prev Cardiol (2023).

Initial systolic blood pressure associates with systemic inflammation, myocardial injury and outcomes in patients with acute coronary syndromes. Winzap, P. A., Kraler, S., Obeid, S., Wenzl, F. A., Templin, C., Klingenberg, R., von Eckardstein, A., Roffi, M., Muller, O., Raber, L. & Luscher, T. F. Eur Heart J Acute Cardiovasc Care (2023).

Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis. Ten Cate, V., Prochaska, J. H., Schulz, A., Nagler, M., Robles, A. P., Jurk, K., Koeck, T., Rapp, S., Duber, C., Munzel, T., Konstantinides, S. V. & Wild, P. S. EClinicalMedicine 59, 101973 (2023).

Continue or discontinue aspirin before non-cardiac surgery? Halvorsen, S., Mehilli, J. & Geisler, T. Eur Heart J (2023).

Targeting long non-coding RNA NUDT6 enhances smooth muscle cell survival and limits vascular disease progression. Winter, H., Winski, G., Busch, A., Chernogubova, E., Fasolo, F., Wu, Z., Backlund, A., Khomtchouk, B. B., Van Booven, D. J., Sachs, N., Eckstein, H. H., Wittig, I., Boon, R. A., Jin, H. & Maegdefessel, L. Mol Ther 31, 1775-1790 (2023).

Acute Outflow Graft Occlusion-A Novel Predictable Complication of Lysis Therapy for the Treatment of Left Ventricular Assist Device Intra-Pump Thrombosis. Hoermandinger, C., Riedler, N., Stein, J., Stawowy, P., Potapov, E., Schoenrath, F. & Just, I. A. ASAIO J (2023).

Minimally Invasive Extirpation of Benign Atrial Cardiac Tumors: Clinical Follow-Up and Survival. Van Praet, K. M., Kofler, M., Wilkens, K., Sundermann, S. H., Meyer, A., Hommel, M., Jacobs, S., Falk, V. & Kempfert, J. Innovations (Phila), 15569845231170000 (2023).

Echocardiography Can Improve the Selection of Mechanical Support Strategies for Patients With Severe COVID-19 Respiratory Distress Syndrome. Dandel, M. ASAIO J (2023).

Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V. Busley, A. V. & Cyganek, L. Stem Cell Res 69, 103108 (2023).

Pitfalls of mitral regurgitation assessment in the presence of mitral valve prolapse. Zach, V., Morris, D. A., Pieske, B. & Schneider-Reigbert, M. Echocardiography (2023).

The prothrombin time/international normalized ratio predicts prognosis in cardiogenic shock. Schupp, T., Behnes, M., Rusnak, J., Dudda, J., Forner, J., Ruka, M., Egner-Walter, S., Bertsch, T., Muller, J. & Akin, I. Coron Artery Dis (2023).

Reactive oxygen species produced by myeloid cells in psoriasis as a potential biofactor contributing to the development of vascular inflammation. Schaller, T., Ringen, J., Fischer, B., Bieler, T., Perius, K., Knopp, T., Kommoss, K. S., Korn, T., Heikenwalder, M., Oelze, M., Daiber, A., Munzel, T., Kramer, D., Wenzel, P., Wild, J., Karbach, S. & Waisman, A. Biofactors (2023).

BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes. Perdreau-Dahl, H., Lipsett, D. B., Frisk, M., Kermani, F., Carlson, C. R., Brech, A., Shen, X., Bergan-Dahl, A., Hou, Y., Tuomainen, T., Tavi, P., Jones, P. P., Lunde, M., Wasserstrom, J. A., Laporte, J., Ullrich, N. D., Christensen, G., Morth, J. P. & Louch, W. E. Circ Res (2023).

Comparative evaluation of three commercially available markerless depth sensors for close-range use in surgical simulation. Burger, L., Sharan, L., Karl, R., Wang, C., Karck, M., De Simone, R., Wolf, I., Romano, G. & Engelhardt, S. Int J Comput Assist Radiol Surg 18, 1109-1118 (2023).

An interferon gamma response signature links myocardial aging and immunosenescence. Ashour, D., Rebs, S., Arampatzi, P., Saliba, A. E., Dudek, J., Schulz, R., Hofmann, U., Frantz, S., Cochain, C., Streckfuss-Bomeke, K. & Ramos, G. C. Cardiovasc Res (2023).

Effects of S-pindolol in mouse pancreatic and lung cancer cachexia models. Springer, J., Jove, Q., de Lima Junior, E. A., Ladron, N. A., Lopez-Soriano, F. J., Busquets, S., Argiles, J. M. & Marks, D. L. J Cachexia Sarcopenia Muscle 14, 1244-1248 (2023).

Association Between Ferritin Levels and Altitude-Dependent Cardiorespiratory Fitness in Mountain Guides. Puhringer, R., Muckenthaler, M. & Burtscher, M. High Alt Med Biol 24, 139-143 (2023).

Personalized diagnosis in suspected myocardial infarction. Neumann, J. T., Twerenbold, R., Ojeda, F., Aldous, S. J., Allen, B. R., Apple, F. S., Babel, H., Christenson, R. H., Cullen, L., Di Carluccio, E., Doudesis, D., Ekelund, U., Giannitsis, E., Greenslade, J., Inoue, K., Jernberg, T., Kavsak, P., Keller, T., Lee, K. K., Lindahl, B., Lorenz, T., Mahler, S. A., Mills, N. L., Mokhtari, A., Parsonage, W., Pickering, J. W., Pemberton, C. J., Reich, C., Richards, A. M., Sandoval, Y., Than, M. P., Toprak, B., Troughton, R. W., Worster, A., Zeller, T., Ziegler, A., Blankenberg, S. & group, A. s. Clin Res Cardiol (2023).

Ordinal pattern-based complexity analysis of high-dimensional chaotic time series. Kottlarz, I. & Parlitz, U. Chaos 33 (2023).

Differential effects of anaemia and iron deficiency on long-term outcomes following transcatheter edge-to-edge repair in degenerative vs. secondary mitral regurgitation: results from a large single-center study. Khurrami, S., Koll, B., Ludwig, S., Pauschinger, C., Weimann, J., Reichenspurner, H., Conradi, L., Schaefer, A., Blankenberg, S., Lubos, E., Schofer, N. & Kalbacher, D. Clin Res Cardiol (2023).

Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V. Busley, A. V., Kleinsorge, M. & Cyganek, L. Stem Cell Res 69, 103105 (2023).


Paper of the Month

Immobility-associated thromboprotection is conserved across mammalian species from bear to human. Thienel, M., Muller-Reif, J. B., Zhang, Z., Ehreiser, V., Huth, J., Shchurovska, K., Kilani, B., Schweizer, L., Geyer, P. E., Zwiebel, M., Novotny, J., Lusebrink, E., Little, G., Orban, M., Nicolai, L., El Nemr, S., Titova, A., Spannagl, M., Kindberg, J., Evans, A. L., Mach, O., Vogel, M., Tiedt, S., Ormanns, S., Kessler, B., Dueck, A., Friebe, A., Jorgensen, P. G., Majzoub-Altweck, M., Blutke, A., Polzin, A., Stark, K., Kaab, S., Maier, D., Gibbins, J. M., Limper, U., Frobert, O., Mann, M., Massberg, S. & Petzold, T. Science380, 178-187 (2023).

IDH3gamma functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart. Nanadikar, M. S., Vergel Leon, A. M., Guo, J., van Belle, G. J., Jatho, A., Philip, E. S., Brandner, A. F., Bockmann, R. A., Shi, R., Zieseniss, A., Siemssen, C. M., Dettmer, K., Brodesser, S., Schmidtendorf, M., Lee, J., Wu, H., Furdui, C. M., Brandenburg, S., Burgoyne, J. R., Bogeski, I., Riemer, J., Chowdhury, A., Rehling, P., Bruegmann, T., Belousov, V. V. & Katschinski, D. M.Nat Commun 14, 2123 (2023).

Gut microbiome and atrial fibrillation-results from a large population-based study. Palmu, J., Borschel, C. S., Ortega-Alonso, A., Marko, L., Inouye, M., Jousilahti, P., Salido, R. A., Sanders, K., Brennan, C., Humphrey, G. C., Sanders, J. G., Gutmann, F., Linz, D., Salomaa, V., Havulinna, A. S., Forslund, S. K., Knight, R., Lahti, L., Niiranen, T. & Schnabel, R. B. EBioMedicine 91, 104583 (2023).

Transgenic angiotensin-converting enzyme 2 overexpression in the rat vasculature protects kidneys from ageing-induced injury. Sanad, A. M., Qadri, F., Popova, E., Rodrigues, A. F., Heinbokel, T., Quach, S., Schulz, A., Bachmann, S., Kreutz, R., Alenina, N. & Bader, M. Kidney Int (2023).

Multicenter comparison of transcatheter aortic valve implantation with the self-expanding ACURATE neo2 versus Evolut PRO transcatheter heart valves. Rheude, T., Pellegrini, C., Landt, M., Bleiziffer, S., Wolf, A., Renker, M., Neuser, J., Dorr, O., Allali, A., Rudolph, T. K., Wambach, J. M., Widder, J. D., Singh, P., Berliner, D., Alvarez-Covarrubias, H. A., Richardt, G., Xhepa, E., Kim, W. K. & Joner, M. Clin Res Cardiol (2023).

[Acceptance of telemetric care for patients with sICD safety advice : Qualitative interview study in cardiological health services research]. Konig, L., Grunberg, E., Xynogalos, P., Thomas, D., Rivinius, R., Frey, N., Ullrich, C. & Rahm, A. K. Herzschrittmacherther Elektrophysiol (2023).

Hypoalbuminaemia and secondary mitral regurgitation mortality: an inevitable fate? Karam, N. & Hausleiter, J. Eur J Heart Fail (2023).

Hyponatraemia and changes in natraemia during hospitalization for acute heart failure and associations with in-hospital and long-term outcomes - from the ESC HFA EORP Heart Failure Long-Term Registry. Kaplon-Cieslicka, A., Benson, L., Chioncel, O., Crespo-Leiro, M. G., Coats, A. J. S., Anker, S. D., Ruschitzka, F., Hage, C., Drozdz, J., Seferovic, P., Rosano, G. M. C., Piepoli, M., Mebazaa, A., McDonagh, T., Lainscak, M., Savarese, G., Ferrari, R., Mullens, W., Bayes-Genis, A., Maggioni, A. P., Lund, L. H., Heart Failure Association of the European Society of, C. & the, E. S. C. H. F. L.-T. R. I. Eur J Heart Fail (2023).

Safety and performance of the third-generation drug-eluting resorbable coronary magnesium scaffold system in the treatment of subjects with de novo coronary artery lesions: 6-month results of the prospective, multicenter BIOMAG-I first-in-human study. Haude, M., Wlodarczak, A., van der Schaaf, R. J., Torzewski, J., Ferdinande, B., Escaned, J., Iglesias, J. F., Bennett, J., Toth, G., Joner, M., Toelg, R., Wiemer, M., Olivecrona, G., Vermeersch, P., Garcia-Garcia, H. M. & Waksman, R. EClinicalMedicine 59, 101940 (2023).

Explant vs Redo-TAVR After Transcatheter Valve Failure: Mid-Term Outcomes From the EXPLANTORREDO-TAVR International Registry. Tang, G. H. L., Zaid, S., Kleiman, N. S., Goel, S. S., Fukuhara, S., Marin-Cuartas, M., Kiefer, P., Abdel-Wahab, M., De Backer, O., Sondergaard, L., Saha, S., Hagl, C., Wyler von Ballmoos, M., Bhadra, O., Conradi, L., Grubb, K. J., Shih, E., DiMaio, J. M., Szerlip, M., Vitanova, K., Ruge, H., Unbehaun, A., Kempfert, J., Pirelli, L., Kliger, C. A., Van Mieghem, N., Hokken, T. W., Adrichem, R., Modine, T., Corona, S., Wang, L., Petrossian, G., Robinson, N., Meier, D., Webb, J. G., Cheung, A., Ramlawi, B., Herrmann, H. C., Desai, N. D., Andreas, M., Mach, M., Waksman, R., Schults, C. C., Ahmad, H., Goldberg, J. B., Geirsson, A., Forrest, J. K., Denti, P., Belluschi, I., Ben-Ali, W., Asgar, A. W., Taramasso, M., Rovin, J. D., Di Eusanio, M., Colli, A., Kaneko, T., Nazif, T. N., Leon, M. B., Bapat, V. N., Mack, M. J., Reardon, M. J. & Sathananthan, J. JACC Cardiovasc Interv 16, 927-941 (2023).

The Correlation of Age and Extension Length in DeBakey Type I Aortic Dissection: Are older patients over 70 years at a lower risk? Merkle-Storms, J., Gaisendrees, C., Feisst, M., Rylski, B., Dohle, D. S., Hagl, C., Lescan, M., Brickwede, J., Poeling, J., Holubec, T., Etz, C. D., Jawny, P., Noack, T., Arif, R., Wahlers, T., Boening, A. & Luehr, M. Eur J Cardiothorac Surg (2023).

The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Gatsiou, A., Tual-Chalot, S., Napoli, M., Ortega-Gomez, A., Regen, T., Badolia, R., Cesarini, V., Garcia-Gonzalez, C., Chevre, R., Ciliberti, G., Silvestre-Roig, C., Martini, M., Hoffmann, J., Hamouche, R., Visker, J. R., Diakos, N., Wietelmann, A., Silvestris, D. A., Georgiopoulos, G., Moshfegh, A., Schneider, A., Chen, W., Guenther, S., Backs, J., Kwak, S., Selzman, C. H., Stamatelopoulos, K., Rose-John, S., Trautwein, C., Spyridopoulos, I., Braun, T., Waisman, A., Gallo, A., Drakos, S. G., Dimmeler, S., Sperandio, M., Soehnlein, O. & Stellos, K. Immunity 56, 979-997 e911 (2023).

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SVEP1 influences monocyte to macrophage differentiation via integrin alpha4beta1/alpha9beta1 and Rho/Rac signalling. Andrews, S. L., Ghaderi-Najafabadi, M., Gong, P., Shamkhi, N., Carleton, L., Schofield, C., Kessler, T., Samani, N. J., Webb, T. R. & Morris, G. E. Biochim Biophys Acta Mol Cell Res 1870, 119479 (2023).

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MicroRNA-216a is Essential for Cardiac Angiogenesis. Juni, R. P., Kocken, J. M. M., Abreu, R. C., Ottaviani, L., Davalan, T., Duygu, B., Poels, E., Vasilevich, A., Hegenbarth, J., Appari, M., Bitsch, N., Olieslagers, S., Schrijvers, D. M., Stoll, M., Heineke, J., de Boer, J., de Windt, L. J. & da Costa Martins, P. A. Mol Ther (2023).

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Potential Global Impact of Sodium-Glucose Cotransporter-2 Inhibitors in Heart Failure. Talha, K. M., Butler, J., Greene, S. J., Aggarwal, R., Anker, S. D., Claggett, B. L., Docherty, K. F., Solomon, S. D., McMurray, J. J. V., Januzzi, J. L., Jr., Vaduganathan, M. & Fonarow, G. C. Eur J Heart Fail (2023).

High-power chargers for electric vehicles: are they safe for patients with pacemakers and defibrillators? Lennerz, C., Schaarschmidt, C., Blazek, P., Knoll, K., Kottmaier, M., Reents, T., Bourier, F., Lengauer, S., Popa, M., Wimbauer, K., Bahlke, F., Krafft, H., Englert, F., Friedrich, L., Schunkert, H., Hessling, G., Deisenhofer, I., Kolb, C. & O'Connor, M. Europace (2023).

A machine learning derived echocardiographic algorithm identifies people at risk of heart failure with distinct cardiac structure, function, and response to spironolactone: findings from the HOMAGE trial. Kobayashi, M., Huttin, O., Ferreira, J. P., Duarte, K., Gonzalez, A., Heymans, S., Verdonschot, J. A. J., Rocca, H. B., Pellicori, P., Clark, A. L., Petutschnigg, J., Edelmann, F., Cleland, J. G., Rossignol, P., Zannad, F., Girerd, N., Committees, H. T. & Investigators. Eur J Heart Fail (2023).

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Effect of Intravenous Iron Replacement on Recurrent Heart Failure Hospitalizations and Cardiovascular Mortality in Patients with Heart Failure and Iron Deficiency: A Bayesian Meta-Analysis. Anker, S. D., Shahzeb Khan, M., Butler, J., von Haehling, S., Jankowska, E. A., Ponikowski, P. & Friede, T. Eur J Heart Fail (2023).

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Multimorbidity patterns and mortality in older adults: Results from the KORA-Age study. Arshadipour, A., Thorand, B., Linkohr, B., Ladwig, K. H., Heier, M. & Peters, A. Front Nutr 10, 1146442 (2023).

Characteristics and outcome of wearable cardioverter-defibrillator therapy stratified by gender: Insights from a multicenter international registry. Abumayyaleh, M., Koepsel, K., Aweimer, A., Ewers, A., Erath, J. W., Kuntz, T., Klein, N., Kovacs, B., Duru, F., Saguner, A. M., Blockhaus, C., Shin, D. I., Gotzmann, M., Lapp, H., Beiert, T., Mugge, A., El-Battrawy, I. & Akin, I. J Cardiovasc Electrophysiol (2023).

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis. Weinstock, J. S., Gopakumar, J., Burugula, B. B., Uddin, M. M., Jahn, N., Belk, J. A., Bouzid, H., Daniel, B., Miao, Z., Ly, N., Mack, T. M., Luna, S. E., Prothro, K. P., Mitchell, S. R., Laurie, C. A., Broome, J. G., Taylor, K. D., Guo, X., Sinner, M. F., von Falkenhausen, A. S., Kaab, S., Shuldiner, A. R., O'Connell, J. R., Lewis, J. P., Boerwinkle, E., Barnes, K. C., Chami, N., Kenny, E. E., Loos, R. J. F., Fornage, M., Hou, L., Lloyd-Jones, D. M., Redline, S., Cade, B. E., Psaty, B. M., Bis, J. C., Brody, J. A., Silverman, E. K., Yun, J. H., Qiao, D., Palmer, N. D., Freedman, B. I., Bowden, D. W., Cho, M. H., DeMeo, D. L., Vasan, R. S., Yanek, L. R., Becker, L. C., Kardia, S. L. R., Peyser, P. A., He, J., Rienstra, M., Van der Harst, P., Kaplan, R., Heckbert, S. R., Smith, N. L., Wiggins, K. L., Arnett, D. K., Irvin, M. R., Tiwari, H., Cutler, M. J., Knight, S., Muhlestein, J. B., Correa, A., Raffield, L. M., Gao, Y., de Andrade, M., Rotter, J. I., Rich, S. S., Tracy, R. P., Konkle, B. A., Johnsen, J. M., Wheeler, M. M., Smith, J. G., Melander, O., Nilsson, P. M., Custer, B. S., Duggirala, R., Curran, J. E., Blangero, J., McGarvey, S., Williams, L. K., Xiao, S., Yang, M., Gu, C. C., Chen, Y. I., Lee, W. J., Marcus, G. M., Kane, J. P., Pullinger, C. R., Shoemaker, M. B., Darbar, D., Roden, D. M., Albert, C., Kooperberg, C., Zhou, Y., Manson, J. E., Desai, P., Johnson, A. D., Mathias, R. A., Consortium, N. T.-O. f. P. M., Blackwell, T. W., Abecasis, G. R., Smith, A. V., Kang, H. M., Satpathy, A. T., Natarajan, P., Kitzman, J. O., Whitsel, E. A., Reiner, A. P., Bick, A. G. & Jaiswal, S. Nature(2023).

Cardiovascular magnetic resonance-derived left atrioventricular coupling index and major adverse cardiac events in patients following acute myocardial infarction. Lange, T., Backhaus, S. J., Schulz, A., Evertz, R., Kowallick, J. T., Bigalke, B., Hasenfuss, G., Thiele, H., Stiermaier, T., Eitel, I. & Schuster, A. J Cardiovasc Magn Reson 25, 24 (2023).

Timing of invasive coronary angiography in NSTE-ACS - An updated individual patient data meta-analysis. Jobs, A., Collet, J. P. & Thiele, H. Eur Heart J Acute Cardiovasc Care (2023).

Impact of mitral regurgitation aetiology on the outcomes of transcatheter aortic valve implantation. Doldi, P. M., Steffen, J., Stolz, L., Fischer, J., Stocker, T. J., Orban, M., Theiss, H., Rizas, K., Sadoni, S., Hagl, C., Massberg, S., Hausleiter, J., Braun, D. & Deseive, S. EuroIntervention (2023).

Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation. Melo, U. S., Jatzlau, J., Prada-Medina, C. A., Flex, E., Hartmann, S., Ali, S., Schopflin, R., Bernardini, L., Ciolfi, A., Moeinzadeh, M. H., Klever, M. K., Altay, A., Vallecillo-Garcia, P., Carpentieri, G., Delledonne, M., Ort, M. J., Schwestka, M., Ferrero, G. B., Tartaglia, M., Brusco, A., Gossen, M., Strunk, D., Geissler, S., Mundlos, S., Stricker, S., Knaus, P., Giorgio, E. & Spielmann, M. Nat Commun 14, 2034 (2023).

Post-stroke cardiovascular management: Current concepts, integrated care and future developments. Lip, G. Y. H., Lenarczyk, R., Pastori, D., Ntaios, G., Doehner, W. & Schnabel, R. Curr Probl Cardiol, 101738 (2023).

Interaction of Natriuretic Peptide Levels and Ejection Fraction on Outcomes with Dapagliflozin and Empagliflozin in Heart Failure. Butler, J., Siddiqi, T. J., Zannad, F., Ferreira, J. P., Fillipatos, G., Anker, S. D. & Packer, M. Eur J Heart Fail (2023).

A novel saline-based occlusion tool allows for dye-less cryoballoon-based pulmonary vein isolation and fluoroscopy reduction. Rottner, L., Obergassel, J., Borof, K., My, I., Moser, F., Lemoine, M., Wenzel, J. P., Kirchhof, P., Ouyang, F., Reissmann, B., Metzner, A. & Rillig, A. Front Cardiovasc Med 10, 1156500 (2023).

Accounting for blood attenuation in intravascular near-infrared fluorescence-ultrasound imaging using a fluorophore-coated guidewire. Rauschendorfer, P., Wissmeyer, G., Jaffer, F. A., Gorpas, D. & Ntziachristos, V. J Biomed Opt 28, 046001 (2023).

Mutations in phosphodiesterase 3A (PDE3A) Cause Hypertension Without Cardiac Damage. Ercu, M., Walter, S. & Klussmann, E. Hypertension (2023).

Left ventricular myocardial strain responding to chronic pressure overload in patients with resistant hypertension evaluated by feature-tracking CMR. Chen, H., Brunner, F. J., Ozden, C., Wenzel, U. O., Neumann, J. T., Erley, J., Saering, D., Muellerleile, K., Maas, K. J., Schoennagel, B. P., Cavus, E., Schneider, J. N., Blankenberg, S., Koops, A., Adam, G. & Tahir, E. Eur Radiol (2023).

The Effect of Sacubitril/Valsartan on Left Ventricular Myocardial Deformation in Heart Failure with Preserved Ejection Fraction (PARAMOUNT trial). Biering-Sorensen, T., Lassen, M. C. H., Shah, A., Claggett, B., Zile, M., Pieske, B., Pieske-Kraigher, E., Voors, A., Shi, V., Lefkowitz, M., Packer, M., McMurray, J. J. V., Solomon, S. D. & Investigators, P. J Card Fail (2023).

Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation. Wittig, J., Drekolia, M. K., Kyselova, A., Delgado Lagos, F., Bochenek, M. L., Hu, J., Schafer, K., Fleming, I. & Bibli, S. I. Redox Biol 62, 102694 (2023).

Digital Health Nudging to increase physical activity in pediatric patients with congenital heart disease: A randomized controlled trial. Willinger, L., Oberhoffer-Fritz, R., Ewert, P. & Muller, J. Am Heart J(2023).

Clinical phenotype of adolescent and adult patients with extracranial vascular malformation. Tuleja, A., Bernhard, S., Hamvas, G., Andreoti, T. A., Rossler, J., Boon, L. M., Vikkula, M., Kammer, R., Haupt, F., Doring, Y. & Baumgartner, I. J Vasc Surg Venous Lymphat Disord (2023).

Generation of two homozygous SHOX2 knock-out human induced pluripotent stem cell lines using CRISPR/Cas9. Radecke, K., Gore, A., Burau, K., Laugsch, M., Kohler, K., Rappold, G. A. & Hoffmann, S. Stem Cell Res 69, 103089 (2023).

B4GALNT3 regulates glycosylation of sclerostin and bone mass. Moverare-Skrtic, S., Voelkl, J., Nilsson, K. H., Nethander, M., Luong, T. T. D., Alesutan, I., Li, L., Wu, J., Horkeby, K., Lagerquist, M. K., Koskela, A., Tuukkanen, J., Tobias, J. H., Lerner, U. H., Henning, P. & Ohlsson, C. EBioMedicine 91, 104546 (2023).

Association of branched-chain amino acids with mortality-the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Moissl, A. P., Lorkowski, S., Meinitzer, A., Pilz, S., Scharnagl, H., Delgado, G. E., Kleber, M. E., Kramer, B. K., Pieske, B., Grubler, M. R., Brussee, H., von Lewinski, D., Toplak, H., Fahrleitner-Pammer, A., Marz, W. & Tomaschitz, A. iScience 26, 106459 (2023).

Zfp580 inactivation as a new therapeutic target to enhance recovery after stroke in mice. Hoffmann, C. J., Kuffner, M. T., Koschutzke, L., Lorenz, S., Lips, J., Boehm-Sturm, P., Mueller, S., Koch, S. P., An, J., Fekonja, L. S., Bugaeva, P., Rex, A., Tunnemann, G. L., Endres, M. & Harms, C. J Cereb Blood Flow Metab, 271678X231168499 (2023).

FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells. Wong, D., Auguste, G., Lino Cardenas, C. L., Turner, A. W., Chen, Y., Song, Y., Ma, L., Perry, R. N., Aherrahrou, R., Kuppusamy, M., Yang, C., Mosquera, J. V., Dube, C. J., Khan, M. D., Palmore, M., Kalra, J., Kavousi, M., Peyser, P. A., Matic, L., Hedin, U., Manichaikul, A., Sonkusare, S. K., Civelek, M., Kovacic, J. C., Bjorkegren, J. L. M., Malhotra, R. & Miller, C. L. Circ Res 132, 1144-1161 (2023).

Longitudinal association between N-terminal B-type natriuretic peptide, anxiety and social support in patients with HFpEF: results from the multicentre randomized controlled Aldo-DHF trial. Wilke, M. R., Broschmann, D., Sandek, A., Wachter, R., Edelmann, F. & Herrmann-Lingen, C. BMC Cardiovasc Disord 23, 184 (2023).

Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes. Seibertz, F., Sutanto, H., Dulk, R., Pronto, J. R. D., Springer, R., Rapedius, M., Liutkute, A., Ritter, M., Jung, P., Stelzer, L., Husgen, L. M., Klopp, M., Rubio, T., Fakuade, F. E., Mason, F. E., Hartmann, N., Pabel, S., Streckfuss-Bomeke, K., Cyganek, L., Sossalla, S., Heijman, J. & Voigt, N. Basic Res Cardiol 118, 14 (2023).

Physical activity in polluted air: an urgent call to study the health risks. Hahad, O., Daiber, A. & Munzel, T. Lancet Planet Health 7, e266-e267 (2023).

Comparison of First-generation and Third-generation Dual-source Computed Tomography for Detecting Coronary Artery Disease in Patients Evaluated for Transcatheter Aortic Valve Replacement. Renker, M., Steinbach, R., Schoepf, U. J., Fischer-Rasokat, U., Choi, Y. H., Hamm, C. W., Rolf, A. & Kim, W. K. J Thorac Imaging (2023).

In atrial fibrillation epilepsy risk differs between oral anticoagulants: active comparator, nested case-control study. Platzbecker, K., Muller-Fielitz, H., Foraita, R., Koepp, M. J., Voss, A., Pflock, R., Linder, R., Pigeot, I., Schink, T. & Schwaninger, M. Europace (2023).

Correction: Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Petter, E., Scheibenbogen, C., Linz, P., Stehning, C., Wirth, K., Kuehne, T. & Kelm, M. J Transl Med21, 243 (2023).

Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools. Zawada, D., Kornherr, J., Meier, A. B., Santamaria, G., Dorn, T., Nowak-Imialek, M., Ortmann, D., Zhang, F., Lachmann, M., Dressen, M., Ortiz, M., Mascetti, V. L., Harmer, S. C., Nobles, M., Tinker, A., De Angelis, M. T., Pedersen, R. A., Grote, P., Laugwitz, K. L., Moretti, A. & Goedel, A. Nat Commun14, 1722 (2023).

Swiss Cohort & Biobank-An Ambitious and Timely Large-Scale Cohort Study. Peters, A. Int J Public Health 68, 1605886 (2023).

Epicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease. Meier, A. B., Zawada, D., De Angelis, M. T., Martens, L. D., Santamaria, G., Zengerle, S., Nowak-Imialek, M., Kornherr, J., Zhang, F., Tian, Q., Wolf, C. M., Kupatt, C., Sahara, M., Lipp, P., Theis, F. J., Gagneur, J., Goedel, A., Laugwitz, K. L., Dorn, T. & Moretti, A. Nat Biotechnol (2023).

Rubella virus infection in endothelial cells reduces angiogenesis via interferon beta-induced CXCL10. Henschke, V., Hild, K., Schilling, E., Haas, J., Filipova, V., Erbe, S., Konig, R., Hubschen, J. M., Laufs, U., Claus, C. & Boeckel, J. N. iScience 26, 106352 (2023).

Does sex affect the risk of 30-day all-cause mortality in cardiogenic shock? Schmitt, A., Schupp, T., Rusnak, J., Ruka, M., Egner-Walter, S., Mashayekhi, K., Tajti, P., Ayoub, M., Behnes, M., Akin, I. & Weidner, K. Int J Cardiol 381, 105-111 (2023).

Depression Subtypes in Patients With Systolic Heart Failure: A Secondary Analysis From the Randomized Controlled Hopeful Heart Trial. Sadlonova, M., Chavanon, M. L., Kwonho, J., Abebe, K. Z., Celano, C. M., Huffman, J., Herbeck Belnap, B. & Rollman, B. L. J Acad Consult Liaison Psychiatry (2023).

The small molecule ACM-001 improves cardiac function in a rat model of severe cancer cachexia. Poetsch, M. S., Palus, S., Van Linthout, S., von Haehling, S., Doehner, W., Coats, A. J. S., Anker, S. D. & Springer, J. Eur J Heart Fail (2023).

Covid-19 pandemic induced traumatizing medical job contents and mental health distortions of physicians working in private practices and in hospitals. Ladwig, K. H., Johar, H., Miller, I., Atasoy, S. & Goette, A. Sci Rep 13, 5284 (2023).

The cusp overlap technique for the Portico valve: it works! Kimx, W. K. Rev Esp Cardiol (Engl Ed) (2023).


Paper of the Month

The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies. Hoffmann, J., Hanss, S., Kraus, M., Schaller, J., Schafer, C., Stahl, D., Anker, S. D., Anton, G., Bahls, T., Blankenberg, S., Blumentritt, A., Boldt, L. H., Cordes, S., Desch, S., Doehner, W., Dorr, M., Edelmann, F., Eitel, I., Endres, M., Engelhardt, S., Erdmann, J., Eulenburg, K., Falk, V., Felix, S. B., Frank, D., Franke, T., Frey, N., Friede, T., Geidel, L., Germans, L., Grabmaier, U., Halle, M., Hausleiter, J., Jakobi, V., Jebran, A. F., Jobs, A., Kaab, S., Karakas, M., Katus, H. A., Klatt, A., Knosalla, C., Krebser, J., Landmesser, U., Lee, M., Lehnert, K., Lesser, S., Leyh, K., Lorbeer, R., Mach-Kolb, S., Meder, B., Nagel, E., Nolte, C. H., Parwani, A. S., Petersmann, A., Puls, M., Rau, H., Reiser, M., Rienhoff, O., Scharfe, T., Schattschneider, M., Scheel, H., Schnabel, R. B., Schuster, A., Schmitt, B., Seidler, T., Seiffert, M., Stahli, B. E., Stas, A., T, J. S., von Stulpnagel, L., Thiele, H., Wachter, R., Wakili, R., Weis, T., Weitmann, K., Wichmann, H. E., Wild, P., Zeller, T., Hoffmann, W., Zeisberg, E. M., Zimmermann, W. H., Krefting, D., Kuhne, T., Peters, A., Hasenfuss, G., Massberg, S., Sommer, T., Dimmeler, S., Eschenhagen, T. & Nauck, M. Clin Res Cardiol(2023).

CAR T-cell cancer therapies: do not forget the heart. Totzeck, M., Anker, M. S. & Rassaf, T. Eur Heart J(2023).

Cardio-hepatic syndrome in patients undergoing transcatheter mitral valve edge-to-edge repair. Stolz, L., Orban, M., Karam, N., Lubos, E., Wild, M., Weckbach, L., Stocker, T. J., Praz, F., Braun, D., Low, K., Hausleiter, S., Stark, K., Doldi, P., Tence, N., Orban, M., Higuchi, S., Haum, M., Windecker, S., Hagl, C., Mayerle, J., Nabauer, M., Kalbacher, D., Massberg, S. & Hausleiter, J. Eur J Heart Fail (2023).

Intraoperative Beat-to-Beat Pulse Transit Time (PTT) Monitoring via Non-Invasive Piezoelectric/Piezocapacitive Peripheral Sensors Can Predict Changes in Invasively Acquired Blood Pressure in High-Risk Surgical Patients. Nordine, M., Pille, M., Kraemer, J., Berger, C., Brandhorst, P., Kaeferstein, P., Kopetsch, R., Wessel, N., Trauzeddel, R. F. & Treskatsch, S. Sensors (Basel) 23 (2023).

Systemic oxidative stress associates with disease severity and outcome in patients with new-onset or worsening heart failure. de Koning, M. L. Y., Emmens, J. E., Romero-Hernandez, E., Bourgonje, A. R., Assa, S., Figarska, S. M., Cleland, J. G. F., Samani, N. J., Ng, L. L., Lang, C. C., Metra, M., Filippatos, G. S., van Veldhuisen, D. J., Anker, S. D., Dickstein, K., Voors, A. A., Lipsic, E., van Goor, H. & van der Harst, P. Clin Res Cardiol, 1-11 (2023).

Current advancements in pharmacotherapy for cancer cachexia. da Fonseca, G. W. P., Sato, R., de Nazare Nunes Alves, M. J. & von Haehling, S. Expert Opin Pharmacother 24, 629-639 (2023).

The relationship between homoarginine and liver biomarkers: a combination of epidemiological and clinical studies. Aghdassi, A., Schwedhelm, E., Atzler, D., Nauck, M., Kuhn, J. P., Kromrey, M. L., Volzke, H., Felix, S. B., Dorr, M., Ittermann, T. & Bahls, M. Sci Rep 13, 5230 (2023).

DNA Methylation Analysis Identifies Novel Epigenetic Loci in Dilated Murine Heart upon Exposure to Volume Overload. Xu, X., Elkenani, M., Tan, X., Hain, J. K., Cui, B., Schnelle, M., Hasenfuss, G., Toischer, K. & Mohamed, B. A. Int J Mol Sci 24 (2023).

Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction. Nurmohamed, N. S., Kraaijenhof, J. M., Mayr, M., Nicholls, S. J., Koenig, W., Catapano, A. L. & Stroes, E. S. G. Eur Heart J(2023).

Efficacy of Tricuspid Valve Direct Annuloplasty and Valve Anatomical Configuration. Mehilli, J. & Zauner, F. JACC Cardiovasc Interv 16, 703-705 (2023).

DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites. Krolevets, M., Cate, V. T., Prochaska, J. H., Schulz, A., Rapp, S., Tenzer, S., Andrade-Navarro, M. A., Horvath, S., Niehrs, C. & Wild, P. S. Clin Epigenetics 15, 56 (2023).

Leaflet Morphology and its Implications for Direct Transcatheter Annuloplasty of Tricuspid Regurgitation. Korber, M. I., Roder, F., Gercek, M., Koell, B., Kalbacher, D., Iliadis, C., Bruwer, M., Friedrichs, K. P., Rudolph, V., Baldus, S. & Pfister, R. JACC Cardiovasc Interv 16, 693-702 (2023).

Membrane remodelling triggers maturation of excitation-contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes. Kermani, F., Mosqueira, M., Peters, K., Lemma, E. D., Rapti, K., Grimm, D., Bastmeyer, M., Laugsch, M., Hecker, M. & Ullrich, N. D. Basic Res Cardiol118, 13 (2023).

Air pollution impacts on in-hospital case-fatality rate of ischemic stroke patients. Keller, K., Haghi, S. H. R., Hahad, O., Schmidtmann, I., Chowdhury, S., Lelieveld, J., Munzel, T. & Hobohm, L. Thromb Res (2023).

Tinnitus Prevalence in the Adult Population-Results from the Gutenberg Health Study. Hackenberg, B., O'Brien, K., Doge, J., Lackner, K. J., Beutel, M. E., Munzel, T., Pfeiffer, N., Schulz, A., Schmidtmann, I., Wild, P. S., Matthias, C. & Bahr-Hamm, K. Medicina (Kaunas) 59 (2023).

Cross-Sectional Association of Dietary Patterns and Supplement Intake with Presence and Gray-Scale Median of Carotid Plaques-A Comparison between Women and Men in the Population-Based Hamburg City Health Study. Assies, J. M., Saltz, M. D., Peters, F., Behrendt, C. A., Jagodzinski, A., Petersen, E. L., Schafer, I., Twerenbold, R., Blankenberg, S., Rimmele, D. L., Thomalla, G., Makarova, N. & Zyriax, B. C.Nutrients 15 (2023).

The association of depressive symptoms and body weight change in midlife - Results from the Gutenberg Health Study in Germany. Werner, A. M., Ernst, M., Brahler, E., Tibubos, A. N., Otten, D., Reiner, I., Wiltink, J., Michal, M., Schulz, A., Wild, P. S., Munzel, T., Konig, J., Lackner, K. J., Pfeiffer, N. & Beutel, M. E. J Affect Disord 332, 115-124 (2023).

Determinants of bone mass in older adults with normal- and overweight derived from the crosstalk with muscle and adipose tissue. Walowski, C. O., Herpich, C., Enderle, J., Braun, W., Both, M., Hasler, M., Muller, M. J., Norman, K. & Bosy-Westphal, A. Sci Rep 13, 5030 (2023).

Combined physicochemical and functional assessment of pertuzumab integrity supports extended in-use stability. Jirschitzka, S., Langle, D., Luck, H., Schade, D. & Kunze, T. Arch Pharm (Weinheim), e2300072 (2023).

Association of immature platelets with perioperative complications in neurosurgery. Anetsberger, A., Bernlochner, I., Jungwirth, B., Blobner, M., Meyer, B., Kochs, E. F., Bongiovanni, D., Schmid, S., Langgartner, C., Baumgart, L. & Gempt, J. Platelets 34, 2185462 (2023).

Characterization of temporal electrical activity patterns for detection of critical isthmus regions of recurrent atypical atrial flutter. Vonderlin, N., Siebermair, J., Mahabadi, A., Pesch, E., Koehler, M., Dobrev, D., Janosi, R. A., Rassaf, T. & Wakili, R. Clin Cardiol 46, 574-583 (2023).

Formin-mediated nuclear actin at androgen receptors promotes transcription. Knerr, J., Werner, R., Schwan, C., Wang, H., Gebhardt, P., Grotsch, H., Caliebe, A., Spielmann, M., Holterhus, P. M., Grosse, R. & Hornig, N. C. Nature (2023).

Fibrinogen reflects severity and predicts outcomes in patients with sepsis and septic shock. Schupp, T., Weidner, K., Rusnak, J., Jawhar, S., Forner, J., Dulatahu, F., Bruck, L. M., Lubke, J., Hoffmann, U., Bertsch, T., Behnes, M. & Akin, I. Blood Coagul Fibrinolysis 34, 161-170 (2023).

Cost-effectiveness of early rhythm control vs. usual care in atrial fibrillation care: an analysis based on data from the EAST-AFNET 4 trial. Gottschalk, S., Kany, S., Konig, H. H., Crijns, H. J., Vardas, P., Camm, A. J., Wegscheider, K., Metzner, A., Rillig, A., Kirchhof, P. & Dams, J. Europace (2023).

Intrarenal Doppler ultrasonography in patients with HFrEF and acute decompensated heart failure undergoing recompensation. Wallbach, M., Valentova, M., Schroeter, M. R., Alkabariti, A., Iraki, I., Leha, A., Tampe, D., Hasenfuss, G., Zeisberg, M., Hellenkamp, K. & Koziolek, M. J. Clin Res Cardiol (2023).

Plasma bioactive adrenomedullin predicts outcome after acute stroke in early rehabilitation. Shafieesabet, A., Jauert, N., Hartmann, O., Arlt, B., Joebges, M. & Doehner, W. Sci Rep 13, 4873 (2023).

Performance evaluation of a novel multi-pinhole collimator on triple-NaI-detector SPECT/CT for dedicated myocardial imaging. Krizsan, A. K., Kukuts, K., Al-Muhanna, W., Szoboszlai, Z., Balazs, L., Szabo, B., Kiss, J., Nekolla, S., Barna, S., Garai, I., Bukki, T. & Forgacs, A. EJNMMI Phys 10, 24 (2023).

Medetomidine/midazolam/fentanyl narcosis alters cardiac autonomic tone leading to conduction disorders and arrhythmias in mice. Tomsits, P., Volz, L., Xia, R., Chivukula, A., Schuttler, D. & Clauss, S.Lab Anim (NY) 52, 85-92 (2023).

Tobacco smoking and vascular biology and function: evidence from human studies. Hahad, O., Kuntic, M., Kuntic, I., Daiber, A. & Munzel, T. Pflugers Arch (2023).

A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study. Duschek, E., Forer, L., Schonherr, S., Gieger, C., Peters, A., Kronenberg, F., Grallert, H. & Lamina, C. Sci Rep 13, 4805 (2023).

Left-ventricular unloading in extracorporeal cardiopulmonary resuscitation due to acute myocardial infarction - A multicenter study. Thevathasan, T., Kenny, M. A., Krause, F. J., Paul, J., Wurster, T., Boie, S. D., Friebel, J., Knie, W., Girke, G., Haghikia, A., Reinthaler, M., Rauch-Krohnert, U., Leistner, D. M., Sinning, D., Frohlich, G., Heidecker, B., Spillmann, F., Praeger, D., Pieske, B., Stangl, K., Landmesser, U., Balzer, F. & Skurk, C. Resuscitation 186, 109775 (2023).

Coffee consumption and associations with blood pressure, LDL-cholesterol and echocardiographic measures in the general population. Senftinger, J., Nikorowitsch, J., Borof, K., Ojeda, F., Aarabi, G., Beikler, T., Mayer, C., Behrendt, C. A., Walther, C., Zyriax, B. C., Twerenbold, R., Blankenberg, S. & Wenzel, J. P. Sci Rep 13, 4668 (2023).

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Occupational life-style programme over 12 months and changes of metabolic risk profile, vascular function, and physical fitness in blue-collar workers. Schaller, N., Blume, K., Hornig, M., Senker, L., Wolfarth, B., Schuster, T., Halle, M., Esefeld, K. & group, M. s. J Occup Med Toxicol 18, 4 (2023).

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Temporal variation in the association between temperature and cause-specific mortality in 15 German cities. Rai, M., Breitner, S., Huber, V., Zhang, S., Peters, A. & Schneider, A. Environ Res 229, 115668 (2023).

Acute type A aortic dissection in adolescents and young adults under 30 years of age: demographics, aetiology and postoperative outcomes of 139 cases. Luehr, M., Yildiz, M., Ma, W. G., Heck, R., Polycarpou, A., Jassar, A., Kreibich, M., Dohle, D. S., Weiss, G., Hagl, C., Rega, F., Schachner, T., Martens, A., Della Corte, A., Osada, H., Sun, L. Z., Tsagakis, K. & Schoenhoff, F. Eur J Cardiothorac Surg 63(2023).

Acute Type A Aortic Dissection in Adolescents and Young Adults under 30 Years of Age: Demographics, Etiology and Postoperative Outcomes of 139 cases. Luehr, M., Yildiz, M., Ma, W. G., Heck, R., Polycarpou, A., Jassar, A., Kreibich, M., Dohle, D. S., Weiss, G., Hagl, C., Rega, F., Schachner, T., Martens, A., Della Corte, A., Osada, H., Sun, L. Z., Tsagakis, K. & Schoenhoff, F. Eur J Cardiothorac Surg(2023).

Implantation of contemporary transcatheter aortic valves in small aortic annuli: the international multicentre TAVI-SMALL 2 registry. Leone, P. P., Regazzoli, D., Pagnesi, M., Cannata, F., Mangieri, A., Hokken, T. W., Costa, G., Barbanti, M., Teles, R. C., Adamo, M., Taramasso, M., Reifart, J., De Marco, F., Giannini, F., Kargoli, F., Ohno, Y., Saia, F., Buono, A., Ielasi, A., Pighi, M., Chiarito, M., Bongiovanni, D., Cozzi, O., Stefanini, G., Ribichini, F. L., Maffeo, D., Chizzola, G., Bedogni, F., Kim, W. K., Maisano, F., Tamburino, C., Van Mieghem, N. M., Colombo, A., Reimers, B. & Latib, A. EuroIntervention (2023).

Skeletal muscle optoacoustics reveals patterns of circulatory function and oxygen metabolism during exercise. Karlas, A., Fasoula, N. A., Katsouli, N., Kallmayer, M., Sieber, S., Schmidt, S., Liapis, E., Halle, M., Eckstein, H. H. & Ntziachristos, V. Photoacoustics 30, 100468 (2023).

History of peripheral artery disease and cardiovascular risk of real-world patients with acute coronary syndrome: Role of inflammation and comorbidities. Denegri, A., Magnani, G., Kraler, S., Bruno, F., Klingenberg, R., Mach, F., Gencer, B., Raber, L., Rodondi, N., Rossi, V. A., Matter, C. M., Nanchen, D., Obeid, S. & Luscher, T. F. Int J Cardiol 382, 76-82 (2023).

Cystic fibrosis transmembrane conductance regulator modulators attenuate platelet activation and aggregation in blood of healthy donors and COVID-19 patients. Asmus, E., Karle, W., Brack, M. C., Wittig, C., Behrens, F., Reinshagen, L., Pfeiffer, M., Schulz, S., Mandzimba-Maloko, B., Erfinanda, L., Perret, P. L., Michalick, L., Smeele, P. J., Lim, E. H. T., van den Brom, C. E., Vonk, A. B. A., Kaiser, T., Suttorp, N., Hippenstiel, S., Sander, L. E., Kurth, F., Rauch, U., Landmesser, U., Haghikia, A., Preissner, R., Bogaard, H. J., Witzenrath, M., Kuebler, W. M., Szulcek, R. & Simmons, S. Eur Respir J 61 (2023).

Influence of Culprit Lesion Intervention on Outcomes in Infarct-Related Cardiogenic Shock With Cardiac Arrest. Zeymer, U., Alushi, B., Noc, M., Mamas, M. A., Montalescot, G., Fuernau, G., Huber, K., Poess, J., de Waha-Thiele, S., Schneider, S., Ouarrak, T., Desch, S., Lauten, A. & Thiele, H. J Am Coll Cardiol81, 1165-1176 (2023).

Mid-regional pro-adrenomedullin and lactate levels for risk stratification in patients with out-of-hospital cardiac arrest. Zelniker, T. A., Schwall, D., Hamidi, F., Steinbach, S., Scheller, P., Spaich, S., Michels, G., Giannitsis, E., Katus, H. A., Frey, N. & Preusch, M. R. Eur Heart J Acute Cardiovasc Care (2023).

Lack of structural brain alterations associated with insomnia: findings from the ENIGMA-Sleep Working Group. Weihs, A., Frenzel, S., Bi, H., Schiel, J. E., Afshani, M., Bulow, R., Ewert, R., Fietze, I., Hoffstaedter, F., Jahanshad, N., Khazaie, H., Riemann, D., Rostampour, M., Stubbe, B., Thomopoulos, S. I., Thompson, P. M., Valk, S. L., Volzke, H., Zarei, M., Eickhoff, S. B., Grabe, H. J., Patil, K. R., Spiegelhalder, K., Tahmasian, M. & Enhancing NeuroImaging Genetics through Meta-Analysis -Sleep Working, G. J Sleep Res, e13884 (2023).

Infarct-Related Artery as a Donor of Collaterals in ST-Segment-Elevation Myocardial Infarction With Concomitant Chronic Total Occlusion: Challenge of the Double-Jeopardy Thesis. Scholz, M., Meyer, T., Maier, L. S. & Scholz, K. H. J Am Heart Assoc 12, e028115 (2023).

Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly. Schnabel, F., Schuler, E., Al-Maawali, A., Chaurasia, A., Syrbe, S., Al-Kindi, A., Bhavani, G. S., Shukla, A., Altmuller, J., Nurnberg, P., Banka, S., Girisha, K. M., Li, Y., Wollnik, B. & Yigit, G. Hum Genet 142, 543-552 (2023).

Improved mid-term stability of MR reduction with an increased number of clips after percutaneous mitral valve repair in functional MR. Sauter, R., Lin, C., Magunia, H., Schreieck, J., Durschmied, D., Gawaz, M., Patzelt, J. & Langer, H. F. Int J Cardiol Heart Vasc 45, 101190 (2023).

Revisiting the obesity paradox in heart failure: what is the best anthropometric index to gauge obesity? Sato, R. & von Haehling, S. Eur Heart J 44, 1154-1156 (2023).

Outcomes of Early Rhythm Control Therapy in Patients With Atrial Fibrillation and a High Comorbidity Burden in Large Real-World Cohorts. Dickow, J., Kany, S., Roth Cardoso, V., Ellinor, P. T., Gkoutos, G. V., Van Houten, H. K., Kirchhof, P., Metzner, A., Noseworthy, P. A., Yao, X. & Rillig, A. Circ Arrhythm Electrophysiol 16, e011585 (2023).

Post-transcriptional control of hemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders. Danckwardt, S., Tregouet, D. A. & Castoldi, E. Cardiovasc Res (2023).

Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure. Oeing, C. U., Pepin, M. E., Saul, K. B., Agircan, A. S., Assenov, Y., Merkel, T. S., Sedaghat-Hamedani, F., Weis, T., Meder, B., Guan, K., Plass, C., Weichenhan, D., Siede, D. & Backs, J. Basic Res Cardiol118, 9 (2023).

Relationship between epicardial adipose tissue attenuation and coronary artery disease in type 2 diabetes mellitus patients. Liu, Z., Neuber, S., Klose, K., Jiang, M., Kelle, S., Zhou, N., Wang, S., Stamm, C. & Luo, F. J Cardiovasc Med (Hagerstown) 24, 244-252 (2023).

Pulmonary Vein Isolation by Pulsed-field Ablation Induces Less Neurocardiac Damage Than Cryoballoon Ablation. Lemoine, M. D., Mencke, C., Nies, M., Obergassel, J., Scherschel, K., Wieboldt, H., Schleberger, R., My, I., Rottner, L., Moser, J., Kany, S., Wenzel, J. P., Moser, F., Dinshaw, L., Munkler, P., Reissmann, B., Ouyang, F., Meyer, C., Blankenberg, S., Zeller, T., Fabritz, L., Rillig, A., Metzner, A. & Kirchhof, P. Circ Arrhythm Electrophysiol 16, e011598 (2023).

A cardiologist's guide to machine learning in cardiovascular disease prognosis prediction. Kresoja, K. P., Unterhuber, M., Wachter, R., Thiele, H. & Lurz, P. Basic Res Cardiol 118, 10 (2023).

Review: Sex-related differences in the treatment of cardiac arrhythmia. Haum, M., Kellnar, A., Thienel, M. & Lackermair, K. Pharmacol Ther 244, 108388 (2023).

A comparative gene expression matrix in Apoe-deficient mice identifies unique and atherosclerotic disease stage-specific gene regulation patterns in monocytes and macrophages. Hardtner, C., Kumar, A., Ehlert, C. A., Vico, T. A., Starz, C., von Ehr, A., Krebs, K., Dufner, B., Hoppe, N., Stachon, P., Heidt, T., Wolf, D., von Zur Muhlen, C., Gruning, B., Robbins, C. S., Maegdefessel, L., Westermann, D., Dederichs, T. S. & Hilgendorf, I. Atherosclerosis 371, 1-13 (2023).

Transcatheter mitral valve replacement will remain a niche therapy: pros and cons. Cohen, D. J., Ludwig, S. & Piazza, N. EuroIntervention 18, 1222-1225 (2023).

Validation of a 0/1 h Algorithm for Rapid Diagnosis of Myocardial Infarction Using a High-Sensitivity Troponin I Assay. Lehmacher, J., Toprak, B., Sorensen, N. A., Bei der Kellen, R., Gossling, A., Hartikainen, T. S., Haller, P. M., Schock, A., Twerenbold, R., Zeller, T., Blankenberg, S., Westermann, D. & Neumann, J. T.Clin Chem 69, 482-491 (2023).

Mosaic loss of Y chromosome in monocytes is associated with lower survival after transcatheter aortic valve replacement. Mas-Peiro, S., Abplanalp, W. T., Rasper, T., Berkowitsch, A., Leistner, D. M., Dimmeler, S. & Zeiher, A. M. Eur Heart J (2023).

Enhanced Ca(2+)-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation. Heijman, J., Zhou, X., Morotti, S., Molina, C. E., Abu-Taha, I. H., Tekook, M., Jespersen, T., Zhang, Y., Dobrev, S., Milting, H., Gummert, J., Karck, M., Kamler, M., El-Armouche, A., Saljic, A., Grandi, E., Nattel, S. & Dobrev, D. Circ Res (2023).

Epiphenomenon or Prognostically Relevant Interventional Target? A Novel Proportionality Framework for Severe Tricuspid Regurgitation. Fortmeier, V., Lachmann, M., Unterhuber, M., Stolz, L., Kassar, M., Ochs, L., Gercek, M., Schober, A. R., Stocker, T. J., Omran, H., Korber, M. I., Hesse, A., Friedrichs, K. P., Yuasa, S., Rudolph, T. K., Joner, M., Pfister, R., Baldus, S., Laugwitz, K. L., Praz, F., Windecker, S., Hausleiter, J., Lurz, P. & Rudolph, V. J Am Heart Assoc 12, e028737 (2023).

Hypoxia to Stimulate Cardiomyocyte Proliferation After MI? A Word of Caution. Eschenhagen, T. Circ Res 132, 741-743 (2023).

Overcoming barriers to timely recognition and treatment of cancer cachexia: Sharing Progress in Cancer Care Task Force Position Paper and Call to Action. Arends, J., Muscaritoli, M., Anker, S., Audisio, R., Barazzoni, R., Bosnjak, S., Bossi, P., Bowman, J., Gijssels, S., Krznaric, Z., Strasser, F. & Aapro, M. Crit Rev Oncol Hematol 185, 103965 (2023).

Resolving the heteromeric composition and macromolecular environment of TRPC channels in the brain. Freichel, M., Tsvilovskyy, V. & Philippaert, K. Cell Calcium 111, 102714 (2023).

Intraprocedural Residual Mitral Regurgitation and Survival After Transcatheter Edge-to-Edge Repair: Prospective German Multicenter Registry (MITRA-PRO). Boekstegers, P., Hausleiter, J., Schmitz, T., Bufe, A., Comberg, T., Seyfarth, M., Frerker, C., Beucher, H., Rottlander, D., Higuchi, S., Ouarrak, T., Schneider, S. & Investigators, M.-P. JACC Cardiovasc Interv 16, 574-585 (2023).

Bayesian MRI reconstruction with joint uncertainty estimation using diffusion models. Luo, G., Blumenthal, M., Heide, M. & Uecker, M. Magn Reson Med (2023).

Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis. Akbulut, A. C., Arisz, R. A., Baaten, C., Baidildinova, G., Barakzie, A., Bauersachs, R., Ten Berg, J., van den Broek, W. W. A., de Boer, H. C., Bonifay, A., Broker, V., Buka, R. J., Ten Cate, H., Ten Cate-Hoek, A. J., Cointe, S., De Luca, C., De Simone, I., Diaz, R. V., Dignat-George, F., Freson, K., Gazzaniga, G., van Gorp, E. C. M., Habibi, A., Henskens, Y. M. C., Iding, A. F. J., Khan, A., Koenderink, G. H., Konkoth, A., Lacroix, R., Lahiri, T., Lam, W., Lamerton, R. E., Lorusso, R., Luo, Q., Maas, C., McCarty, O. J. T., van der Meijden, P. E. J., Meijers, J. C. M., Mohapatra, A. K., Nevo, N., Robles, A. P., Poncelet, P., Reinhardt, C., Ruf, W., Saraswat, R., Schonichen, C., Schutgens, R., Simioni, P., Spada, S., Spronk, H. M. H., Tazhibayeva, K., Thachil, J., Diaz, R. V., Vallier, L., Veninga, A., Verhamme, P., Visser, C., Watson, S. P., Wenzel, P., Willems, R. A. L., Willers, A., Zhang, P., Zifkos, K. & van Zonneveld, A. J. Thromb Haemost (2023).

Efficacy of levosimendan infusion in patients undergoing a left ventricular assist device implant in a propensity score matched analysis of the EUROMACS registry-the Euro LEVO-LVAD study. Abdelshafy, M., Caliskan, K., Simpkin, A. J., Elkoumy, A., Kimman, J. R., Elsherbini, H., Elzomor, H., de By, T., Gollmann-Tepekoylu, C., Berchtold-Herz, M., Loforte, A., Reineke, D., Schoenrath, F., Paluszkiewicz, L., Gummert, J., Mohacsi, P., Meyns, B. & Soliman, O. Eur J Cardiothorac Surg 63 (2023).

Efficacy of Levosimendan Infusion in Patients Undergoing Left Ventricular Assist Device Implantation in a propensity score-matched analysis of the EUROMACS Registry - the Euro LEVO-LVAD Study. Abdelshafy, M., Caliskan, K., Simpkin, A. J., Elkoumy, A., Kimman, J. R., Elsherbini, H., Elzomor, H., de By, T., Gollmann-Tepekoylu, C., Berchtold-Herz, M., Loforte, A., Reineke, D., Schoenrath, F., Paluszkiewicz, L., Gummert, J., Mohacsi, P., Meyns, B. & Soliman, O. Eur J Cardiothorac Surg (2023).

Integrated care for older multimorbid heart failure patients: protocol for the ESCAPE randomized trial and cohort study. Zelenak, C., Nagel, J., Bersch, K., Derendorf, L., Doyle, F., Friede, T., Herbeck Belnap, B., Kohlmann, S., Skou, S. T., Velasco, C. A., Albus, C., Asendorf, T., Bang, C. A., Beresnevaite, M., Bruun, N. E., Burg, M. M., Buhl, S. F., Gaede, P. H., Luhmann, D., Markser, A., Nagy, K. V., Rafanelli, C., Rasmussen, S., Sondergaard, J., Sorensen, J., Stauder, A., Stock, S., Urbinati, S., Riva, D. D., Wachter, R., Walker, F., Pedersen, S. S., Herrmann-Lingen, C. & consortium, E. ESC Heart Fail 10, 2051-2065 (2023).

Myocardial tissue changes detected by cardiac MRI in a patient with suspected systemic sarcoidosis. Vanchin, B., Ka, M. M., Arendt, C. T., Escher, F., Nagel, E. & Puntmann, V. O. BMC Cardiovasc Disord 23, 131 (2023).

Magnetic resonance imaging of organ iron before and after correction of iron deficiency in patients with heart failure. Gertler, C., Jauert, N., Freyhardt, P., Valentova, M., Aland, S. C., Walter-Rittel, T. C., Unterberg-Buchwald, C., Placzek, M., Ding-Reinelt, V., Bekfani, T., Doehner, W., Hasenfuss, G., Hamm, B. & Sandek, A. ESC Heart Fail (2023).

The interplay between micro RNAs and genetic liability to Alzheimer's Disease on memory trajectories in the general population. Van der Auwera, S., Garvert, L., Ameling, S., Volzke, H., Nauck, M., Volker, U. & Grabe, H. J. Psychiatry Res 323, 115141 (2023).

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Autoantibodies targeting G protein-coupled receptors: An evolving history in autoimmunity. Report of the 4th international symposium. Cabral-Marques, O., Moll, G., Catar, R., Preuss, B., Bankamp, L., Pecher, A. C., Henes, J., Klein, R., Kamalanathan, A. S., Akbarzadeh, R., van Oostveen, W., Hohberger, B., Endres, M., Koolmoes, B., Levarht, N., Postma, R., van Duinen, V., van Zonneveld, A. J., de Vries-Bouwstra, J., Fehres, C., Tran, F., do Vale, F. Y. N., da Silva Souza, K. B., Filgueiras, I. S., Schimke, L. F., Baiocchi, G. C., de Miranda, G. C., da Fonseca, D. L. M., Freire, P. P., Hackel, A. M., Grasshoff, H., Stahle, A., Muller, A., Dechend, R., Yu, X., Petersen, F., Sotzny, F., Sakmar, T. P., Ochs, H. D., Schulze-Forster, K., Heidecke, H., Scheibenbogen, C., Shoenfeld, Y. & Riemekasten, G. Autoimmun Rev 22, 103310 (2023).

Associations of accelerometer-based sedentary bouts with adiposity markers among German adults - results from a cross-sectional study. Voigt, L., Ullrich, A., Gross, S., Guertler, D., Jaeschke, L., Dorr, M., van den Berg, N., John, U. & Ulbricht, S. BMC Public Health 23, 469 (2023).

Cardiovascular Magnetic Resonance Rest and Exercise-Stress Left Atrioventricular Coupling Index to Detect Diastolic Dysfunction. Backhaus, S. J., Lange, T., Schulz, A., Evertz, R., Frey, S. M., Hasenfuss, G. & Schuster, A. Am J Physiol Heart Circ Physiol (2023).

Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging. Wahl-Schott, C., Freichel, M., Hennis, K., Philippaert, K., Ottenheijm, R., Tsvilovskyy, V. & Varbanov, H. Handb Exp Pharmacol(2023).

The emergence of the air pollutant ozone as a significant cardiovascular killer? Munzel, T., Hahad, O. & Daiber, A. Eur Heart J (2023).

Incidence and risk factors of myocarditis in hospitalized patients with COVID-19. Keller, K., Sagoschen, I., Konstantinides, S., Gori, T., Munzel, T. & Hobohm, L. J Med Virol (2023).

Effect of Training on Vascular Function and Repair in Heart Failure With Preserved Ejection Fraction. Gevaert, A. B., Bohm, B., Hartmann, H., Goovaerts, I., Stoop, T., Van De Heyning, C. M., Beckers, P. J., Baldassarri, F., Mueller, S., Oberhoffer, R., Duvinage, A., Haykowsky, M. J., Wisloff, U., Adams, V., Pieske, B., Halle, M. & Van Craenenbroeck, E. M. JACC Heart Fail 11, 454-464 (2023).

Associations of myosteatosis with disc degeneration: A 3T magnetic resonance imaging study in individuals with impaired glycaemia. Diallo, T. D., Rospleszcz, S., Fabian, J., Walter, S. S., Maurer, E., Storz, C., Roemer, F., Rathmann, W., Peters, A., Jungmann, P. M., Jung, M., Bamberg, F. & Kiefer, L. S. J Cachexia Sarcopenia Muscle (2023).

Imputation-powered whole-exome analysis identifies genes associated with kidney function and disease in the UK Biobank. Wuttke, M., Konig, E., Katsara, M. A., Kirsten, H., Farahani, S. K., Teumer, A., Li, Y., Lang, M., Gocmen, B., Pattaro, C., Gunzel, D., Kottgen, A. & Fuchsberger, C. Nat Commun 14, 1287 (2023).

Hs-TnT and NT-proBNP independently predict survival and cardiac-related events in adults with congenital heart disease. Willinger, L., Brudy, L., Hacker, A. L., Meyer, M., Hager, A., Oberhoffer-Fritz, R., Ewert, P. & Muller, J. Eur J Cardiovasc Nurs (2023).

P2Y12 inhibitor intensity de-escalation in patients with acute coronary syndromes. Ndrepepa, G. & Kastrati, A. Eur Heart J (2023).

Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure. Markousis-Mavrogenis, G., Minich, W. B., Al-Mubarak, A. A., Anker, S. D., Cleland, J. G. F., Dickstein, K., Lang, C. C., Ng, L. L., Samani, N. J., Zannad, F., Metra, M., Seemann, P., Hoeg, A., Lopez, P., Consortium, B.-C., van Veldhuisen, D. J., de Boer, R. A., Voors, A. A., van der Meer, P., Schomburg, L. & Bomer, N. Cardiovasc Res (2023).

Transcatheter mitral valve replacement or repair for secondary mitral regurgitation: a propensity score-matched analysis. Ludwig, S., Kalbacher, D., Ali, W. B., Weimann, J., Adam, M., Duncan, A., Webb, J. G., Windecker, S., Orban, M., Giannini, C., Coisne, A., Karam, N., Scotti, A., Sondergaard, L., Adamo, M., Muller, D. W. M., Butter, C., Denti, P., Melica, B., Regazzoli, D., Garatti, A., Schmidt, T., Andreas, M., Dahle, G., Taramasso, M., Nickenig, G., Dumonteil, N., Walther, T., Flagiello, M., Kempfert, J., Fam, N., Ruge, H., Rudolph, T. K., Wyler von Ballmoos, M. C., Metra, M., Redwood, S., Granada, J. F., Tang, G. H. L., Latib, A., Lurz, P., von Bardeleben, R. S., Modine, T., Hausleiter, J., Conradi, L., on behalf of the, C.-M. & the Euro, S. M. R. I. Eur J Heart Fail (2023).

Weight-gain independent effect of mirtazapine on fasting plasma lipids in healthy men. Lechner, K., Heel, S., Uhr, M., Dose, T., Holsboer, F., Lucae, S., Schaaf, L., Fulda, S., Kloiber, S. & Hennings, J. M. Naunyn Schmiedebergs Arch Pharmacol (2023).

The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies. Hoffmann, J., Hanss, S., Kraus, M., Schaller, J., Schafer, C., Stahl, D., Anker, S. D., Anton, G., Bahls, T., Blankenberg, S., Blumentritt, A., Boldt, L. H., Cordes, S., Desch, S., Doehner, W., Dorr, M., Edelmann, F., Eitel, I., Endres, M., Engelhardt, S., Erdmann, J., Eulenburg, K., Falk, V., Felix, S. B., Frank, D., Franke, T., Frey, N., Friede, T., Geidel, L., Germans, L., Grabmaier, U., Halle, M., Hausleiter, J., Jakobi, V., Jebran, A. F., Jobs, A., Kaab, S., Karakas, M., Katus, H. A., Klatt, A., Knosalla, C., Krebser, J., Landmesser, U., Lee, M., Lehnert, K., Lesser, S., Leyh, K., Lorbeer, R., Mach-Kolb, S., Meder, B., Nagel, E., Nolte, C. H., Parwani, A. S., Petersmann, A., Puls, M., Rau, H., Reiser, M., Rienhoff, O., Scharfe, T., Schattschneider, M., Scheel, H., Schnabel, R. B., Schuster, A., Schmitt, B., Seidler, T., Seiffert, M., Stahli, B. E., Stas, A., T, J. S., von Stulpnagel, L., Thiele, H., Wachter, R., Wakili, R., Weis, T., Weitmann, K., Wichmann, H. E., Wild, P., Zeller, T., Hoffmann, W., Zeisberg, E. M., Zimmermann, W. H., Krefting, D., Kuhne, T., Peters, A., Hasenfuss, G., Massberg, S., Sommer, T., Dimmeler, S., Eschenhagen, T. & Nauck, M. Clin Res Cardiol (2023).

Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation. Aslan, G. S., Jae, N., Manavski, Y., Fouani, Y., Shumliakivska, M., Kettenhausen, L., Kirchhof, L., Gunther, S., Fischer, A., Luxan, G. & Dimmeler, S. JCI Insight 8 (2023).

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart. Milenkovic, I., Santos Vieira, H. G., Lucas, M. C., Ruiz-Orera, J., Patone, G., Kesteven, S., Wu, J., Feneley, M., Espadas, G., Sabido, E., Hubner, N., van Heesch, S., Volkers, M. & Novoa, E. M. Nucleic Acids Res (2023).

Novel insights in the pathomechanism of Brugada syndrome and fever-related type 1 ECG changes in a preclinical study using human-induced pluripotent stem cell-derived cardiomyocytes. Li, Y., Dinkel, H., Pakalniskyte, D., Busley, A. V., Cyganek, L., Zhong, R., Zhang, F., Xu, Q., Maywald, L., Aweimer, A., Huang, M., Liao, Z., Meng, Z., Yan, C., Pradel, T., Rose, L., Moscu-Gregor, A., Hohn, A., Yang, Z., Qiao, L., Mugge, A., Zhou, X., Akin, I. & El-Battrawy, I. Clin Transl Med 13, e1130 (2023).

Participation in a clinical trial is associated with lower mortality but not lower risk of HF hospitalization in patients with heart failure: observations from the ESC EORP Heart Failure Long-Term Registry. Kapelios, C. J., Benson, L., Crespo-Leiro, M. G., Anker, S. D., Coats, A. J. S., Chioncel, O., Filippatos, G., Lainscak, M., McDonagh, T., Mebazaa, A., Metra, M., Piepoli, M. F., Rosano, G. M. C., Ruschitzka, F., Savarese, G., Seferovic, P. M., Volterrani, M., Maggioni, A. P. & Lund, L. H. Eur Heart J (2023).

Medication-Attributable Adverse Events in Heart Failure Trials. Harrington, J., Fonarow, G. C., Khan, M. S., Hernandez, A., Anker, S., Bohm, M., Greene, S. J., Felker, G. M., Vaduganathan, M. & Butler, J. JACC Heart Fail 11, 425-436 (2023).

GPx3 deficiency exacerbates maladaptive RV remodeling in experimental pulmonary artery banding. Covington, T. A., Pilz, P. M., Mulhern, R. M., Ngoy, S., Loscalzo, A., Liu, J., Fisch, S. & Grune, J. Am J Physiol Lung Cell Mol Physiol (2023).

Associations of body size with all-cause and cause-specific mortality in healthy older adults. Carr, P. R., Webb, K. L., Neumann, J. T., Thao, L. T. P., Beilin, L. J., Ernst, M. E., Fitzgibbon, B., Gasevic, D., Nelson, M. R., Newman, A. B., Orchard, S. G., Owen, A., Reid, C. M., Stocks, N. P., Tonkin, A. M., Woods, R. L. & McNeil, J. J. Sci Rep 13, 3799 (2023).

EGFR and MMP-9 are associated with neointimal hyperplasia in systemic-to-pulmonary shunts in children with complex cyanotic heart disease. Kottmann, P., Eildermann, K., Murthi, S. R., Cleuziou, J., Lemmer, J., Vitanova, K., von Stumm, M., Lehmann, L., Horer, J., Ewert, P., Sigler, M., Lange, R., Lahm, H., Dressen, M., Lichtner, P. & Wolf, C. M. Mamm Genome (2023).

Thrifty energy phenotype predicts weight regain in postmenopausal women with overweight or obesity and is related to FGFR1 signaling. Spranger, L., Weiner, J., Bredow, J., Zeitz, U., Grittner, U., Boschmann, M., Dickmann, S., Stobaus, N., Schwartzenberg, R. J., Brachs, M., Spranger, J. & Mai, K. Clin Nutr42, 559-567 (2023).

Non-nutritional sweeteners and cardiovascular risk. Rizas, K. D., Sams, L. E. & Massberg, S. Nat Med(2023).

Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence. Miller, D. C., Lisowski, P., Genehr, C., Wanker, E. E., Priller, J., Prigione, A. & Diecke, S. Stem Cell Res 68, 103056 (2023).

Allometric body shape indices, T2D and kidney function: A two-sample Mendelian randomization study. Kjaergaard, A. D., Krakauer, J., Krakauer, N., Teumer, A., Winkler, T. W. & Ellervik, C. Diabetes Obes Metab (2023).

Treatment of frequent premature ventricular contractions via a single very high-power short-duration application. Heeger, C. H., Mamaev, R., Eitel, C., Kuck, K. H. & Tilz, R. R. Europace (2023).

The artificial sweetener erythritol and cardiovascular event risk. Witkowski, M., Nemet, I., Alamri, H., Wilcox, J., Gupta, N., Nimer, N., Haghikia, A., Li, X. S., Wu, Y., Saha, P. P., Demuth, I., Konig, M., Steinhagen-Thiessen, E., Cajka, T., Fiehn, O., Landmesser, U., Tang, W. H. W. & Hazen, S. L. Nat Med (2023).

Age differences of patients treated with wearable cardioverter defibrillator: Data from a multicentre registry. El-Battrawy, I., Tenbrink, D., Kovacs, B., Dreher, T. C., Blockhaus, C., Klein, N., Shin, D. I., Hijazi, M., Rosenkaimer, S., Beiert, T., Abumayyaleh, M., Saguner, A. M., Kowitz, J., Erath, J. W., Duru, F., Mugge, A., Aweimer, A. & Akin, I. Eur J Clin Invest, e13977 (2023).


Paper of the Month



Targeting ADAMTS-7: A Vaccination Against Atherosclerosis-and Its Complications? Kessler, T. & Schunkert, H. Circulation 147, 743-745 (2023).

Outcomes in Patients With Early Menopause Who Underwent Transcatheter Aortic Valve Implantation. Edens, M., Watanabe, Y., Nicolas, J., Sartori, S., Snyder, C., Vogel, B., Spirito, A., Tchetche, D., Petronio, A. S., Mehilli, J., Lefevre, T., Presbitero, P., Capranzano, P., Selberg, A., Iadanza, A., Sardella, G., Van Mieghem, N. M., Meliga, E., Dumonteil, N., Fraccaro, C., Trabattoni, D., Mikhail, G., Ferrer-Gracia, M. C., Naber, C., Sharma, S., Morice, M. C., Dangas, G. D., Chieffo, A. & Mehran, R. Am J Cardiol 192, 221-227 (2023).

Homozygous frameshift variant in desmoglein-2 causes biventricular arrhythmogenic right ventricular cardiomyopathy. Ayan, H. N. U., Ali, P. S., Korejo, A. A., Thiele, H., Nurnberg, P., Tariq, M., Jamal, S. Z., Erdmann, J. & Ahmad, I. Clin Genet (2023).

Plasma viscosity, immunoglobulins and risk of cardiovascular disease and mortality: new data and meta-analyses. Lowe, G. D. O., Harris, K., Koenig, W., Ben-Shlomo, Y., Thorand, B., Peters, A., Meisinger, C., Imhof, A., Tunstall-Pedoe, H., Peters, S. A. E. & Woodward, M. J Clin Pathol (2023).

Definition of age-dependent reference values for the diameter of the common bile duct and pancreatic duct on MRCP: a population-based, cross-sectional cohort study. Beyer, G., Kasprowicz, F., Hannemann, A., Aghdassi, A., Thamm, P., Volzke, H., Lerch, M. M., Kuhn, J. P. & Mayerle, J. Gut (2023).

Surgical prehabilitation in older and frail individuals: a scoping review. Sadlonova, M., Katz, N. B., Jurayj, J. S., Flores, L., Celano, C. M., von Arnim, C. A. F. & Silver, J. K. Int Anesthesiol Clin 61, 34-46 (2023).

Aquaporin-2 is not alone. Klussmann, E. Kidney Int 103, 458-460 (2023).

Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism. Grammatika Pavlidou, N., Dobrev, S., Beneke, K., Reinhardt, F., Pecha, S., Jacquet, E., Abu-Taha, I. H., Schmidt, C., Voigt, N., Kamler, M., Schnabel, R. B., Baczko, I., Garnier, A., Reichenspurner, H., Nikolaev, V. O., Dobrev, D. & Molina, C. E. Eur Heart J (2023).

Coronary artery restenosis treatment with plain balloon, drug-coated balloon, or drug-eluting stent: 10-year outcomes of the ISAR-DESIRE 3 trial. Giacoppo, D., Alvarez-Covarrubias, H. A., Koch, T., Cassese, S., Xhepa, E., Kessler, T., Wiebe, J., Joner, M., Hochholzer, W., Laugwitz, K. L., Schunkert, H., Kastrati, A. & Kufner, S. Eur Heart J (2023).

On the role of benchmarking data sets and simulations in method comparison studies. Friedrich, S. & Friede, T. Biom J, e2200212 (2023).

Resilience and stability of the CF- intestinal and respiratory microbiome during nutritional and exercise intervention. Knoll, R. L., Jarquin-Diaz, V. H., Klopp, J., Kemper, A., Hilbert, K., Hillen, B., Pfirrmann, D., Simon, P., Bahner, V., Nitsche, O., Gehring, S., Marko, L., Forslund, S. K. & Poplawska, K. BMC Microbiol 23, 44 (2023).

Erratum: Whole-Mount Immunofluorescence Staining, Confocal Imaging and 3D Reconstruction of the Sinoatrial and Atrioventricular Node in the Mouse. J Vis Exp (2023).

Pirfenidone affects human cardiac fibroblast proliferation and cell cycle activity in 2D cultures and engineered connective tissues. Meyer, F. E. U., Santos, G. L., Doan, T. P., DeGrave, A. N., Bues, B. & Lutz, S. Naunyn Schmiedebergs Arch Pharmacol (2023).

Addressing current challenges in optimization of lipid management following an ACS event: Outcomes of the ACS EuroPath III initiative. Catapano, A. L., De Caterina, R., Jukema, J. W., Klempfner, R., Landmesser, U., Schiele, F. & Sionis, A. Clin Cardiol (2023).

Urinary Marker Profiles in Heart Failure with Reduced Versus Preserved Ejection Fraction. Streng, K. W., Hillege, H. L., Ter Maaten, J. M., van Veldhuisen, D. J., Dickstein, K., Samani, N. J., Ng, L. L., Metra, M., Filippatos, G. S., Ponikowski, P., Zannad, F., Anker, S. D., van der Meer, P., Lang, C. C., Voors, A. A. & Damman, K. J Cardiovasc Transl Res (2023).

Title: Association of aldosterone with mortality in the general population. Then, C., Herder, C., Heier, M., Meisinger, C., Koenig, W., Rathmann, W., Sujana, C., Roden, M., Bidlingmaier, M., Seissler, J., Thorand, B., Peters, A. & Reincke, M. Exp Clin Endocrinol Diabetes (2023).

High on-aspirin treatment platelet reactivity and restenosis after percutaneous coronary intervention: results of the Intracoronary Stenting and Antithrombotic Regimen-ASpirin and Platelet Inhibition (ISAR-ASPI) Registry. Mayer, K., Ndrepepa, G., Schroeter, M., Emmer, C., Bernlochner, I., Schupke, S., Gewalt, S., Hilz, R., Coughlan, J. J., Aytekin, A., Heyken, C., Morath, T., Schunkert, H., Laugwitz, K. L., Sibbing, D. & Kastrati, A. Clin Res Cardiol (2023).

Acute procedural efficacy and safety of a novel cryoballoon for the treatment of paroxysmal atrial fibrillation: results from the POLAR ICE study. Martin, C. A., Tilz, R. R. R., Anic, A., Defaye, P., Luik, A., Asmundis, C., Champ-Rigot, L., Iacopino, S., Sommer, P., Albrecht, E. M., Raybuck, J. D., Richards, E., Cielen, N., Yap, S. C. & Investigators, P. I. J Cardiovasc Electrophysiol (2023).

Derivation and validation of the ISAR score to predict the risk of repeat percutaneous coronary intervention for recurrent drug-eluting stent restenosis. Coughlan, J. J., Aytekin, A., Lahu, S., Scalamogna, M., Wiebe, J., Pinieck, S., Kufner, S., Xhepa, E., Joner, M., Kuna, C., Voll, F., Laugwitz, K. L., Schunkert, H., Kastrati, A. & Cassese, S. EuroIntervention (2023).

Use of mechanical circulatory support in patients with non-ischemic cardiogenic shock. Schrage, B., Sundermeyer, J., Beer, B. N., Bertoldi, L., Bernhardt, A., Blankenberg, S., Dauw, J., Dindane, Z., Eckner, D., Eitel, I., Graf, T., Horn, P., Kirchhof, P., Kluge, S., Linke, A., Landmesser, U., Luedike, P., Lusebrink, E., Mangner, N., Maniuc, O., Winkler, S. M., Nordbeck, P., Orban, M., Pappalardo, F., Pauschinger, M., Pazdernik, M., Proudfoot, A., Kelham, M., Rassaf, T., Reichenspurner, H., Scherer, C., Schulze, P. C., Schwinger, R. H. G., Skurk, C., Sramko, M., Tavazzi, G., Thiele, H., Villanova, L., Morici, N., Wechsler, A., Westenfeld, R., Winzer, E. & Westermann, D. Eur J Heart Fail (2023).

Bone status in men with heart failure: results from the Studies Investigating Co-morbidities Aggravating Heart Failure. Loncar, G., Garfias-Veitl, T., Valentova, M., Vatic, M., Lainscak, M., Obradovic, D., Dschietzig, T. B., Doehner, W., Jankowska, E. A., Anker, S. D. & von Haehling, S. Eur J Heart Fail (2023).

Sex Differences in 10-Year Outcomes After Percutaneous Coronary Intervention With Drug-Eluting Stents: Insights From the DECADE Cooperation. Coughlan, J. J., Raber, L., Brugaletta, S., Kufner, S., Maeng, M., Jensen, L. O., Ortega-Paz, L., Bar, S., Laugwitz, K. L., Madsen, M., Heg, D., Aytekin, A., Windecker, S., Olesen, K. K. W., Sabate, M., Kastrati, A. & Cassese, S. Circulation 147, 575-585 (2023).

The MyoPulser field stimulator, a do it yourself programmable electronic pacemaker for contracting cells and tissues. Ott, C. & Jung, T. Sci Rep 13, 2461 (2023).

An Early Indication of Higher In-Hospital Mortality Risk Among Patients with SARS-CoV-2 Pneumonia. Dandel, M. J Am Soc Echocardiogr (2023).

Evaluation of right atrial function by two-dimensional echocardiography and strain imaging in patients with RCA CTO recanalization. Blessing, R., Drosos, I., Munzel, T., Wenzel, P., Gori, T. & Dimitriadis, Z. BMC Cardiovasc Disord 23, 85 (2023).

Effects of empagliflozin on left ventricular diastolic function in addition to usual care in individuals with type 2 diabetes mellitus-results from the randomized, double-blind, placebo-controlled EmDia trial. Prochaska, J. H., Junger, C., Schulz, A., Arnold, N., Muller, F., Heidorn, M. W., Baumkotter, R., Zahn, D., Koeck, T., Trobs, S. O., Lackner, K. J., Daiber, A., Binder, H., Shah, S. J., Gori, T., Munzel, T. & Wild, P. S. Clin Res Cardiol (2023).

Regional extracellular volume within late gadolinium enhancement-positive myocardium to differentiate cardiac sarcoidosis from myocarditis of other etiology: a cardiovascular magnetic resonance study. Treiber, J., Novak, D., Fischer-Rasokat, U., Wolter, J. S., Kriechbaum, S., Weferling, M., von Jeinsen, B., Hain, A., Rieth, A. J., Siemons, T., Keller, T., Hamm, C. W. & Rolf, A. J Cardiovasc Magn Reson25, 8 (2023).

Aberrant phase separation and nucleolar dysfunction in rare genetic diseases. Mensah, M. A., Niskanen, H., Magalhaes, A. P., Basu, S., Kircher, M., Sczakiel, H. L., Reiter, A. M. V., Elsner, J., Meinecke, P., Biskup, S., Chung, B. H. Y., Dombrowsky, G., Eckmann-Scholz, C., Hitz, M. P., Hoischen, A., Holterhus, P. M., Hulsemann, W., Kahrizi, K., Kalscheuer, V. M., Kan, A., Krumbiegel, M., Kurth, I., Leubner, J., Longardt, A. C., Moritz, J. D., Najmabadi, H., Skipalova, K., Snijders Blok, L., Tzschach, A., Wiedersberg, E., Zenker, M., Garcia-Cabau, C., Buschow, R., Salvatella, X., Kraushar, M. L., Mundlos, S., Caliebe, A., Spielmann, M., Horn, D. & Hnisz, D. Nature (2023).

Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo. Kulaj, K., Harger, A., Bauer, M., Caliskan, O. S., Gupta, T. K., Chiang, D. M., Milbank, E., Reber, J., Karlas, A., Kotzbeck, P., Sailer, D. N., Volta, F., Lutter, D., Prakash, S., Merl-Pham, J., Ntziachristos, V., Hauner, H., Pfaffl, M. W., Tschop, M. H., Muller, T. D., Hauck, S. M., Engel, B. D., Gerdes, J. M., Pfluger, P. T., Krahmer, N. & Stemmer, K. Nat Commun 14, 709 (2023).

Robotic stereotactic body radiotherapy for localized prostate cancer: final analysis of the German HYPOSTAT trial. Krug, D., Imhoff, D., Haidenberger, A., Hessler, N., Schafer, J., Huttenlocher, S., Chatzikonstantinou, G., Furweger, C., Ramm, U., Konig, I. R., Chun, F., Staehler, M., Rodel, C., Muacevic, A., Vonthein, R., Dunst, J. & Blanck, O. Strahlenther Onkol (2023).

Quantification of physical activity with prospective activity tracking after transfemoral aortic valve replacement. Haum, M., Humpfer, F., Steffen, J., Fischer, J., Stocker, T. J., Sadoni, S., Theiss, H., Braun, D., Orban, M., Rizas, K., Massberg, S., Hausleiter, J. & Deseive, S. Int J Cardiol (2023).

High glucose leads to redistribution of the proteasomal system. Grune, T., Schnell, V. & Jung, T.Biofactors (2023).

DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice. de Boer, M., Te Lintel Hekkert, M., Chang, J., van Thiel, B. S., Martens, L., Bos, M. M., de Kleijnen, M. G. J., Ridwan, Y., Octavia, Y., van Deel, E. D., Blonden, L. A., Brandt, R. M. C., Barnhoorn, S., Bautista-Nino, P. K., Krabbendam-Peters, I., Wolswinkel, R., Arshi, B., Ghanbari, M., Kupatt, C., de Windt, L. J., Danser, A. H. J., van der Pluijm, I., Remme, C. A., Stoll, M., Pothof, J., Roks, A. J. M., Kavousi, M., Essers, J., van der Velden, J., Hoeijmakers, J. H. J. & Duncker, D. J. Aging Cell, e13768 (2023).

Effects of Remote Patient Management on Self-Care Behaviour in Heart Failure Patients: Results from the randomised TIM-HF2 Trial. Deckwart, O., Koehler, K., Lezius, S., Prescher, S., Koehler, F. & Winkler, S. Eur J Cardiovasc Nurs (2023).

European Society of Cardiology quality indicators for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Aktaa, S., Tzeis, S., Gale, C. P., Ackerman, M. J., Arbelo, E., Behr, E. R., Crotti, L., d'Avila, A., de Chillou, C., Deneke, T., Figueiredo, M., Friede, T., Leclercq, C., Merino, J. L., Semsarian, C., Verstrael, A., Zeppenfeld, K., Tfelt-Hansen, J. & Reichlin, T. Europace 25, 199-210 (2023).

How can we improve the evidence base for the treatment and care for patients with congenital heart disease? Uebing, A. & Hitz, M. P. Eur Heart J (2023).

Translating principles of quality control to cardiovascular magnetic resonance: assessing quantitative parameters of the left ventricle in a large cohort. Riazy, L., Dauber, S., Lange, S., Viezzer, D. S., Ott, S., Wiesemann, S., Blaszczyk, E., Muhlberg, F., Zange, L. & Schulz-Menger, J. Sci Rep 13, 2205 (2023).

Cardiac radioablation of incessant ventricular tachycardia in patients with terminal heart failure under permanent left ventricular assist device therapy-description of two cases. Mehrhof, F., Bergengruen, P., Gerds-Li, J. H., Jahn, A., Kluge, A. K., Parwani, A., Zips, D., Boldt, L. H. & Schonrath, F.Strahlenther Onkol (2023).

Comparison of plug-based versus suture-based vascular closure for large-bore arterial access: a collaborative meta-analysis of observational and randomized studies. Dumpies, O., Jobs, A., Obradovic, D., van Wiechen, M., Hartung, P., Rotta Detto Loria, J., Wilde, J., Majunke, N., Kiefer, P., Noack, T., Thiele, H., van Mieghem, N., Desch, S. & Abdel-Wahab, M. Clin Res Cardiol (2023).

Immunodeficiency is prevalent in congenital heart disease and associated with increased risk of emergency admissions and death. Diller, G. P., Lammers, A. E., Fischer, A., Orwat, S., Nienhaus, K., Schmidt, R., Radke, R. M., De-Torres-Alba, F., Kaleschke, G., Marschall, U., Bauer, U. M., Roth, J., Gerss, J., Bormann, E. & Baumgartner, H. Eur Heart J (2023).

Introduction of a cascaded segmentation pipeline for parametric T1 mapping in cardiovascular magnetic resonance to improve segmentation performance. Viezzer, D., Hadler, T., Ammann, C., Blaszczyk, E., Fenski, M., Grandy, T. H., Wetzl, J., Lange, S. & Schulz-Menger, J. Sci Rep 13, 2103 (2023).

Expert opinion: How to treat type IA endoleakage. Peterss, S., Stana, J., Rantner, B., Buech, J., Radner, C., Konstantinou, N., Hagl, C., Pichlmaier, M. & Tsilimparis, N. Asian Cardiovasc Thorac Ann, 2184923231154742 (2023).

Angiotensin Deficient FVB/N Mice are Normotensive. Rodrigues, A. F., Todiras, M., Qadri, F., Alenina, N. & Bader, M. Br J Pharmacol (2023).

Spironolactone effect on circulating procollagen type I carboxy-terminal propeptide: Pooled analysis of three randomized trials. Ferreira, J. P., Cleland, J. G., Girerd, N., Rossignol, P., Pellicori, P., Cosmi, F., Mariottoni, B., Gonzalez, A., Diez, J., Solomon, S. D., Claggett, B., Pfeffer, M. A., Pitt, B., Petutschnigg, J., Pieske, B., Edelmann, F. & Zannad, F. Int J Cardiol (2023).

Machine learning identifies pathophysiologically and prognostically informative phenotypes among patients with mitral regurgitation undergoing transcatheter edge-to-edge repair. Trenkwalder, T., Lachmann, M., Stolz, L., Fortmeier, V., Covarrubias, H. A. A., Rippen, E., Schurmann, F., Presch, A., von Scheidt, M., Ruff, C., Hesse, A., Gercek, M., Mayr, N. P., Ott, I., Schuster, T., Harmsen, G., Yuasa, S., Kufner, S., Hoppmann, P., Kupatt, C., Schunkert, H., Kastrati, A., Laugwitz, K. L., Rudolph, V., Joner, M., Hausleiter, J. & Xhepa, E. Eur Heart J Cardiovasc Imaging (2023).

Population-based reference values for 4D flow MRI derived aortic blood flow parameters. Schafstedde, M., Jarmatz, L., Bruning, J., Hullebrand, M., Nordmeyer, S., Harloff, A. & Hennemuth, A.Physiol Meas 44 (2023).

Circulating cardiac biomarkers, structural brain changes, and dementia: Emerging insights and perspectives. Jensen, M., Zeller, T., Twerenbold, R. & Thomalla, G. Alzheimers Dement (2023).

North and East African mitochondrial genetic variation needs further characterization towards precision medicine. Fahnrich, A., Stephan, I., Hirose, M., Haarich, F., Awadelkareem, M. A., Ibrahim, S., Busch, H. & Wohlers, I. J Adv Res (2023).

New Cerebral Microbleeds After Catheter-Based Structural Heart Interventions: An Exploratory Analysis. Braemswig, T. B., Kusserow, M., Bellmann, B., Beckhoff, F., Reinthaler, M., von Rennenberg, R., Erdur, H., Scheitz, J. F., Galinovic, I., Villringer, K., Leistner, D. M., Audebert, H. J., Endres, M., Landmesser, U., Haeusler, K. G., Fiebach, J. B., Lauten, A., Rillig, A. & Nolte, C. H. J Am Heart Assoc 12, e8189 (2023).

Predictive model of transcriptional elongation control identifies trans regulatory factors from chromatin signatures. Akcan, T. S., Vilov, S. & Heinig, M. Nucleic Acids Res (2023).

Epigenetic aging in patients diagnosed with coronary artery disease: results of the LipidCardio study. Banszerus, V. L., Konig, M., Landmesser, U., Vetter, V. M. & Demuth, I. Clin Epigenetics 15, 16 (2023).

Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9. Weihs, A., Chaker, L., Martin, T. C., Braun, K. V. E., Campbell, P. J., Cox, S. R., Fornage, M., Gieger, C., Grabe, H. J., Grallert, H., Harris, S. E., Kuhnel, B., Marioni, R. E., Martin, N. G., McCartney, D. L., McRae, A. F., Meisinger, C., van Meurs, J. B. J., Nano, J., Nauck, M., Peters, A., Prokisch, H., Roden, M., Selvin, E., Beekman, M., van Heemst, D., Slagboom, E. P., Swenson, B. R., Tin, A., Tsai, P. C., Uitterlinden, A., Visser, W. E., Volzke, H., Waldenberger, M., Walsh, J. P., Kottgen, A., Wilson, S. G., Peeters, R. P., Bell, J. T., Medici, M. & Teumer, A. Thyroid (2023).

Impact of ferric carboxymaltose for iron deficiency at discharge after heart failure hospitalisation: A European multinational economic evaluation. McEwan, P., Harrison, C., Binnie, R., Lewis, R. D., Cohen-Solal, A., Lund, L. H., Ohlsson, M., von Haehling, S., Comin-Colet, J., Pascual-Figal, D. A., Wachter, S., Dorigotti, F., de Arellano, A. R., Ponikowski, P. & Jankowska, E. A. Eur J Heart Fail (2023).

Eligibility for sotagliflozin in a real-world heart failure population based on the SOLOIST-WHF trial enrolment criteria: Data from the swedish heart failure registry. Becher, P. M., Savarese, G., Benson, L., Dahlstrom, U., Karlstrom, P., Mol, P. G. M., Metra, M., Bhatt, D. L., Pitt, B. & Lund, L. H. Eur Heart J Cardiovasc Pharmacother (2023).

Myocardial Characterization with Extracellular Volume Mapping with a First-Generation Photon-counting Detector CT with MRI Reference. Aquino, G. J., O'Doherty, J., Schoepf, U. J., Ellison, B., Byrne, J., Fink, N., Zsarnoczay, E., Wolf, E. V., Allmendinger, T., Schmidt, B., Flohr, T., Baruah, D., Suranyi, P., Varga-Szemes, A. & Emrich, T. Radiology, 222030 (2023).


Paper of the Month

Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation. DZHK authors: Carina Mauersberger, Hendrik Sager, Tan An Dang, Laura Lambrecht, Heribert Schunkert, Thorsten Kessler. Nat Cardiovasc Res (2022). doi: 10.1038/s44161-022-00175-w

A step towards disentangling the complex relationship between vitamin D and kidney function. Teumer, A. & Rebholz, C. M. J Clin Endocrinol Metab (2023).  

Single-cell RNA-based phenotyping reveals a pivotal role of thyroid hormone receptor alpha for hypothalamic development. Sreenivasan, V. K. A., Dore, R., Resch, J., Maier, J., Dietrich, C., Henck, J., Balachandran, S., Mittag, J. & Spielmann, M. Development 150 (2023).  

Prevalence and patterns of in-stent neoatherosclerosis in lower extremity artery disease. Muller, A., Bradaric, C., Kafka, A., Joner, M., Cassese, S., Xhepa, E., Kufner, S., Kastrati, A., Laugwitz, K. L., Ibrahim, T. & Koppara, T. EuroIntervention (2023).  

DNA methylation analysis identifies novel genetic loci associated with circulating fibrinogen levels in blood. Hahn, J., Bressler, J., Domingo-Relloso, A., Chen, M. H., McCartney, D. L., Teumer, A., van Dongen, J., Kleber, M. E., Aissi, D., Swenson, B. R., Yao, J., Zhao, W., Huang, J., Xia, Y., Brown, M. R., Costeira, R., de Geus, E. J. C., Delgado, G. E., Dobson, D. A., Elliott, P. et al. J Thromb Haemost (2023).  

CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2. Cachorro, E., Gunscht, M., Schubert, M., Sadek, M. S., Siegert, J., Dutt, F., Bauermeister, C., Quickert, S., Berning, H., Nowakowski, F., Lammle, S., Firneburg, R., Luo, X., Kunzel, S. R., Klapproth, E., Mirtschink, P., Mayr, M., Dewenter, M., Vettel, C., Heijman, J. et al. Circ Res (2023).  

Iliofemoral artery predilation prior to transfemoral transcatheter aortic valve implantation in patients with aortic valve stenosis and advanced peripheral artery disease. Alvarez-Covarrubias, H. A., Joner, M., Cassese, S., Warmbrunn, M., Lutz, J., Trenkwalder, T., Seguchi, M., Aytekin, A., Presch, A., Pellegrini, C., Rheude, T., Patrick Mayr, N., Kufner, S., Schunkert, H., Kastrati, A. & Xhepa, E. Catheter Cardiovasc Interv (2023).  

Effects of a 2-year exercise training on neuromuscular system health in older individuals with low muscle function. Monti, E., Tagliaferri, S., Zampieri, S., Sarto, F., Sirago, G., Franchi, M. V., Ticinesi, A., Longobucco, Y., Adorni, E., Lauretani, F., Von Haehling, S., Marzetti, E., Calvani, R., Bernabei, R., Cesari, M., Maggio, M. & Narici, M. V. J Cachexia Sarcopenia Muscle (2023).  

Interaction of polystyrene nanoparticles with supported lipid bilayers: Impact of nanoparticle size and protein corona. Meesaragandla, B., Blessing, D. O., Karanth, S., Rong, A., Geist, N. & Delcea, M. Macromol Biosci, e2200464 (2023).  

Aircraft noise exposure induces pro-inflammatory vascular conditioning and amplifies vascular dysfunction and impairment of cardiac function after myocardial infarction. Molitor, M., Jimenez, M. T. B., Hahad, O., Witzler, C., Finger, S., Garlapati, V. S., Rajlic, S., Knopp, T., Bieler, T., Aluia, M., Wild, J., Lagrange, J., Blessing, R., Rapp, S., Schulz, A., Kleinert, H., Karbach, S., Steven, S., Ruf, W., Wild, P. et al.Cardiovasc Res (2023).  

FOXO3A acts as immune response modulator in human virus-negative inflammatory cardiomyopathy. Makrutzki-Zlotek, K., Escher, F., Karadeniz, Z., Aleshcheva, G., Pietsch, H., Kuchler, K., Schultheiss, H. P., Heidecker, B., Poller, W., Landmesser, U., Scheibenbogen, C., Thevathasan, T. & Skurk, C. Heart (2023).  

Increase of c-FOS promoter transcriptional activity by the dual leucine zipper kinase. Koster, K. A., Duque Escobar, J., Fietkau, A., Toledo, R. & Oetjen, E. Naunyn Schmiedebergs Arch Pharmacol (2023).  

miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus. Hulshoff, M. S., Schellinger, I. N., Xu, X., Fledderus, J., Rath, S. K., Wong, F. C., Maamari, S., Haunschild, J., Krenning, G., Raaz, U. & Zeisberg, E. M. Diabetol Metab Syndr 15, 11 (2023).  

The endothelial-enriched lncRNA LINC00607 mediates angiogenic function. Boos, F., Oo, J. A., Warwick, T., Gunther, S., Izquierdo Ponce, J., Lopez, M., Rafii, D., Buchmann, G., Pham, M. D., Msheik, Z. S., Li, T., Seredinski, S., Haydar, S., Kashefiolasl, S., Plate, K. H., Behr, R., Mietsch, M., Krishnan, J., Pullamsetti, S. S., Bibli, S. I. et al. Basic Res Cardiol 118, 5 (2023).  

[Interventional treatment of heart failure : Stents and valves]. Becher, P. M. & Seiffert, M. Herz (2023).  

Staging Heart Failure Patients With Secondary Mitral Regurgitation Undergoing Transcatheter Edge-to-Edge Repair. Stolz, L., Doldi, P. M., Orban, M., Karam, N., Puscas, T., Wild, M. G., Popescu, A., von Bardeleben, R. S., Iliadis, C., Baldus, S., Adamo, M., Thiele, H., Besler, C., Unterhuber, M., Ruf, T., Pfister, R., Higuchi, S., Koell, B., Giannini, C., Petronio, A. et al. JACC Cardiovasc Interv 16, 140-151 (2023).  

How arrhythmias weaken the ventricle: an often underestimated vicious cycle. Kortl, T., Schach, C. & Sossalla, S. Herz (2023).  

First case report of fully robotically assisted lithotripsy in heavily calcified left main stenosis. Hofmann, F. J., Dorr, O., Blachutzik, F., Boeder, N. F., Elsasser, A., Mollmann, H. & Nef, H. M. Eur Heart J Case Rep 7, ytac427 (2023).  

Concomitant latent pulmonary vascular disease leads to impaired global cardiac performance in HFpEF. Schuster, A., Schulz, A., Lange, T., Evertz, R., Hartmann, F., Kowallick, J. T., Hellenkamp, K., Uecker, M., Seidler, T., Hasenfuss, G. & Backhaus, S. J. Eur J Heart Fail (2023).  

Safety of Stress Cardiac Magnetic Resonance in Patients With Moderate to Severe Aortic Valve Stenosis. Salatzki, J., Ochs, A., Kirchgassner, N., Heins, J., Seitz, S., Hund, H., Mereles, D., Friedrich, M. G., Katus, H. A., Frey, N., Andre, F. & Ochs, M. M. J Cardiovasc Imaging 31, 26-38 (2023).  

When too much is too much: noncoding duplications in skin disorders. Yumiceba, V. & Spielmann, M. Br J Dermatol 188, e2-e3 (2023).  

Early sudden distal conductor fracture of a stylet-driven lead implanted for left bundle branch area pacing. Thaler, R., Sinner, M. F., Joghetaei, N. & Fichtner, S. HeartRhythm Case Rep 9, 28-30 (2023).  

Women physicians in cardiovascular magnetic resonance: Past, present, and future. Sierra-Galan, L. M., Aggarwal, N. R., Stojanovska, J., Raman, S. V., Han, Y., Ferreira, V. M., Thomas, K., Seiberlich, N., Parwani, P., Bucciarelli-Ducci, C., Baldassarre, L. A., Mavrogeni, S., Ordovas, K., Schulz-Menger, J. & Bandettini, W. P. Front Cardiovasc Med 9, 984326 (2022).  

Editorial: Insights in cardiovascular imaging: 2021. Parasa, R., Weiss, K. J., Bourantas, C. V., Petersen, S. E., Kelle, S. & Thomson, R. J. Front Cardiovasc Med 9, 1061337 (2022).  

Mitral valve transcatheter edge-to-edge repair. Hausleiter, J., Stocker, T. J., Adamo, M., Karam, N., Swaans, M. J. & Praz, F. EuroIntervention 18, 957-976 (2023).

CMR detects decreased myocardial deformation in asymptomatic patients at risk for heart failure. Hashemi, D., Doeblin, P., Blum, M., Weiss, K. J., Schneider, M., Korosoglou, G., Beyer, R. E., Pieske, B., Edelmann, F. & Kelle, S. Front Cardiovasc Med 9, 1091768 (2022).  

Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution. Fleischer, J. R., Schmitt, A. M., Haas, G., Xu, X., Zeisberg, E. M., Bohnenberger, H., Kuffer, S., Teuwen, L. A., Karras, P. J., Beissbarth, T., Bleckmann, A., Planque, M., Fendt, S. M., Vermeulen, P., Ghadimi, M., Kalucka, J., De Oliveira, T. & Conradi, L. C. Mol Cancer 22, 17 (2023).  

Left atrial appendage closure in end-stage renal disease and hemodialysis: Data from a German multicenter registry. Fink, T., Paitazoglou, C., Bergmann, M. W., Sano, M., Keelani, A., Sciacca, V., Saad, M., Eitel, C., Heeger, C. H., Skurk, C., Landmesser, U., Thiele, H., Stiermaier, T., Fuernau, G., Reil, J. C., Frey, N., Kuck, K. H., Tilz, R. R., Sandri, M. & Eitel, I. Catheter Cardiovasc Interv (2023).  

The Greifswald Post COVID Rehabilitation Study and Research (PoCoRe)-Study Design, Characteristics and Evaluation Tools. Steinmetz, A., Bahlmann, S., Bergelt, C., Broker, B. M., Ewert, R., Felix, S. B., Floel, A., Fleischmann, R., Hoffmann, W., Holtfreter, S., Nauck, M., Riemann, K., Scheer, C., Stahl, D., Vogelgesang, A., Volker, U., Wiesmann, U., Klinger-Konig, J., Walk, R., Grabe, H. J. et al. J Clin Med 12(2023).  

Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling. Schoger, E., Bleckwedel, F., Germena, G., Rocha, C., Tucholla, P., Sobitov, I., Mobius, W., Sitte, M., Lenz, C., Samak, M., Hinkel, R., Varga, Z. V., Giricz, Z., Salinas, G., Gross, J. C. & Zelarayan, L. C. Commun Biol 6, 79 (2023).  

Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants. Rinne, S., Oertli, A., Nagel, C., Tomsits, P., Jenewein, T., Kaab, S., Kauferstein, S., Loewe, A., Beckmann, B. M. & Decher, N. Int J Mol Sci 24 (2023).  

Resting membrane potential is less negative in trabeculae from right atrial appendages of women, but action potential duration does not shorten with age. Pecha, S., Ismaili, D., Geelhoed, B., Knaut, M., Reichenspurner, H., Eschenhagen, T., Schnabel, R. B., Christ, T. & Ravens, U. J Mol Cell Cardiol 176, 1-10 (2023).  

Long-term risk associated with clonal hematopoiesis in patients with severe aortic valve stenosis undergoing TAVR. Mas-Peiro, S., Pergola, G., Berkowitsch, A., Meggendorfer, M., Rieger, M. A., Vasa-Nicotera, M., Dimmeler, S. & Zeiher, A. M. Clin Res Cardiol (2023).  

Macrophages: From Simple Phagocyte to an Integrative Regulatory Cell for Inflammation and Tissue Regeneration-A Review of the Literature. Mamilos, A., Winter, L., Schmitt, V. H., Barsch, F., Grevenstein, D., Wagner, W., Babel, M., Keller, K., Schmitt, C., Gurtler, F., Schreml, S., Niedermair, T., Rupp, M., Alt, V. & Brochhausen, C. Cells 12 (2023).  

Serum Starvation Accelerates Intracellular Metabolism in Endothelial Cells. Lorenz, M., Fritsche-Guenther, R., Bartsch, C., Vietzke, A., Eisenberger, A., Stangl, K., Stangl, V. & Kirwan, J. A. Int J Mol Sci 24(2023).  

New Insights into the Basic and Translational Aspects of AMPK Signaling. Ladilov, Y. & Aslam, M. Cells12 (2023).  

Deciphering the Effect of Different Genetic Variants on Hippocampal Subfield Volumes in the General Population. Kirchner, K., Garvert, L., Wittfeld, K., Ameling, S., Bulow, R., Meyer Zu Schwabedissen, H., Nauck, M., Volzke, H., Grabe, H. J. & Van der Auwera, S. Int J Mol Sci 24 (2023).  

Effects of Exercise and Omega-3-Supplemented, High-Protein Diet on Inflammatory Markers in Serum, on Gene Expression Levels in PBMC, and after Ex Vivo Whole-Blood LPS Stimulation in Old Adults. Hass, U., Heider, S., Kochlik, B., Herpich, C., Pivovarova-Ramich, O. & Norman, K. Int J Mol Sci 24(2023).  

Intestinal Barrier Dysfunction and Microbial Translocation in Patients with First-Diagnosed Atrial Fibrillation. Blobaum, L., Witkowski, M., Wegner, M., Lammel, S., Schencke, P. A., Jakobs, K., Puccini, M., Reissner, D., Steffens, D., Landmesser, U., Rauch, U. & Friebel, J. Biomedicines 11 (2023).  

Metabolomic Profiling in Patients with Different Hemodynamic Subtypes of Severe Aortic Valve Stenosis. Bengel, P., Elkenani, M., Beuthner, B. E., Pietzner, M., Mohamed, B. A., Pollok-Kopp, B., Kratzner, R., Toischer, K., Puls, M., Fischer, A., Binder, L., Hasenfuss, G. & Schnelle, M. Biomolecules 13 (2023).  

Radiomics in Cardiac Computed Tomography. Ayx, I., Froelich, M. F., Baumann, S., Papavassiliu, T. & Schoenberg, S. O. Diagnostics (Basel) 13 (2023).  

Endothelial Glycocalyx and Cardiomyocyte Damage Is Prevented by Recombinant Syndecan-1 in Acute Myocardial Infarction. Vahldieck, C., Cianflone, E., Fels, B., Loning, S., Depelmann, P., Sabatino, J., Salerno, N., Karsten, C. M., Torella, D., Weil, J., Sun, D., Goligorsky, M. S. & Kusche-Vihrog, K. Am J Pathol(2023).  

Is only-child status associated with a higher blood pressure in adolescence? An observational study. Pantke, P. M., Herrmann-Lingen, C., Rothenberger, A., Poustka, L. & Meyer, T. Eur J Pediatr (2023).  

Sex-specific associations between systolic, diastolic and pulse pressure and hemostatic parameters in the population-based KORA-Fit study: a cross-sectional study. Vogel von Falckenstein, J., Freuer, D., Peters, A., Heier, M., Linseisen, J. & Meisinger, C. Thromb J 21, 7 (2023).  

Kidney outcome after mild to moderate COVID-19. Schmidt-Lauber, C., Hanzelmann, S., Schunk, S., Petersen, E. L., Alabdo, A., Lindenmeyer, M., Hausmann, F., Kuta, P., Renne, T., Twerenbold, R., Zeller, T., Blankenberg, S., Fliser, D. & Huber, T. B. Nephrol Dial Transplant (2023).  

Reduction of permanent pacemaker implantation by using the cusp overlap technique in transcatheter aortic valve replacement: a meta-analysis. Rawish, E., Macherey, S., Jurczyk, D., Patz, T., Jose, J., Stiermaier, T., Eitel, I., Frerker, C. & Schmidt, T. Clin Res Cardiol (2023).  

Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial. Hohneck, A., Meissner, R., Reyser, C., Heinemann, L., Christians, K., Merx, K., Weingartner, S., Mavratzas, A., Schulte, N., Burkholder, I., Hofmann, W. K. & Hofheinz, R. D. Oncol Res Treat 46, 1-10 (2023).  

Prognostic impact and diagnostic value of invasively derived hemodynamic measures in patients with severe aortic stenosis undergoing TAVI. Grundmann, D., Gossling, A., Schmidt, L., Voigtlaender, L., Ludwig, S., Linder, M., Waldschmidt, L., Demal, T., Bhadra, O. D., Schaefer, A., Reichenspurner, H., Blankenberg, S., Conradi, L., Westermann, D., Seiffert, M. & Schofer, N. Clin Res Cardiol (2023).  

Association of cerebrospinal fluid brain-binding autoantibodies with cognitive impairment in post-COVID-19 syndrome. Franke, C., Boesl, F., Goereci, Y., Gerhard, A., Schweitzer, F., Schroeder, M., Foverskov-Rasmussen, H., Heine, J., Quitschau, A., Kandil, F. I., Schild, A. K., Finke, C., Audebert, H. J., Endres, M., Warnke, C. & Pruss, H. Brain Behav Immun 109, 139-143 (2023).  

Predictive value of late gadolinium enhancement cardiovascular magnetic resonance in patients with persistent atrial fibrillation: dual-centre validation of a standardized method. Althoff, T. F., Eichenlaub, M., Padilla-Cueto, D., Lehrmann, H., Garre, P., Schoechlin, S., Ferro, E., Invers, E., Ruile, P., Hein, M., Schlett, C., Figueras, I. V. R. M., Prat-Gonzalez, S., Mueller-Edenborn, B., Bohnen, M., Porta-Sanchez, A., Tolosana, J. M., Guasch, E., Roca-Luque, I., Arbelo, E. et al. Eur Heart J Open 3, oeac085 (2023).  

Prognostic impact of age and gender on patients with electrical storm. Weidner, K. J., Schupp, T., Rusnak, J., Muller, J., Taton, G., Reiser, L., Bollow, A., Reichelt, T., Ellguth, D., Engelke, N., Barre, M., Grosse Meininghaus, D., Hoppner, J., El-Battrawy, I., Mashayekhi, K., Akin, I. & Behnes, M. Cardiol J (2023).  

Cardiac splicing as a diagnostic and therapeutic target. Gotthardt, M., Badillo-Lisakowski, V., Parikh, V. N., Ashley, E., Furtado, M., Carmo-Fonseca, M., Schudy, S., Meder, B., Grosch, M., Steinmetz, L., Crocini, C. & Leinwand, L. Nat Rev Cardiol (2023).  

Imaging Targets to Visualize the Cardiac Immune Landscape in Heart Failure. Wienecke, L. M., Leid, J. M., Leuschner, F. & Lavine, K. J. Circ Cardiovasc Imaging 16, e014071 (2023).   

Glycolytic side pathways regulating macrophage inflammatory phenotypes and functions. Dionisio, F., Tomas, L. & Schulz, C. Am J Physiol Cell Physiol (2023).  

Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform. Bojkova, D., Reus, P., Panosch, L., Bechtel, M., Rothenburger, T., Kandler, J. D., Pfeiffer, A., Wagner, J. U. G., Shumliakivska, M., Dimmeler, S., Olmer, R., Martin, U., Vondran, F. W. R., Toptan, T., Rothweiler, F., Zehner, R., Rabenau, H. F., Osman, K. L., Pullan, S. T., Carroll, M. W. et al. iScience26, 105944 (2023).  

Type D personality as a risk factor for adverse outcome in patients with cardiovascular disease: an individual patient data meta-analysis. Lodder, P., Wicherts, J. M., Antens, M., Albus, C., Bessonov, I. S., Conden, E., Dulfer, K., Gostoli, S., Grande, G., Hedberg, P., Herrmann-Lingen, C., Jaarsma, T., Koo, M., Lin, P., Lin, T. K., Meyer, T., Pushkarev, G., Rafanelli, C., Raykh, O. I., de Quadros, A. S. et al. Psychosom Med(2023).  

Trans-fatty acid blood levels of industrial but not natural origin are associated with cardiovascular risk factors in patients with HFpEF: a secondary analysis of the Aldo-DHF trial. Lechner, K., Bock, M., von Schacky, C., Scherr, J., Lorenz, E., Lechner, B., Haller, B., Krannich, A., Halle, M., Wachter, R., Duvinage, A. & Edelmann, F. Clin Res Cardiol (2023).  

DeepSom: a CNN-based approach to somatic variant calling in WGS samples without a matched normal. Vilov, S. & Heinig, M. Bioinformatics 39 (2023).

Preclinical evaluation of the degradation kinetics of third-generation resorbable magnesium scaffolds. Seguchi, M., Baumann-Zumstein, P., Fubel, A., Waksman, R., Haude, M., Galli, S. & Joner, M. EuroIntervention (2023).  

Economic Evaluation of a Mobile Stroke Unit Service in Germany. Oliveira Goncalves, A. S., Rohmann, J. L., Piccininni, M., Kurth, T., Ebinger, M., Endres, M., Freitag, E., Harmel, P., Lorenz-Meyer, I., Rohrpasser-Napierkowski, I., Busse, R. & Audebert, H. J. Ann Neurol (2023).  

CTA-determined tricuspid annular dilatation is associated with persistence of tricuspid regurgitation after transcatheter aortic valve replacement. Low, K., Steffen, J., Theiss, H., Orban, M., Rizas, K. D., Haum, M., Doldi, P. M., Stolz, L., Gmeiner, J., Hagl, C., Massberg, S., Hausleiter, J., Braun, D. & Deseive, S. Clin Res Cardiol (2023).  

Impact of preoperative mitral regurgitation on LVAD patients: propensity-score matched analysis of the EUROMACS dataset. Loforte, A., Nersesian, G., Lewin, D., Lanmueller, P., Gliozzi, G., Stein, J., Cavalli, G. G., Schoenrath, F., Netuka, I., Zimpfer, D., de By, T., Gummert, J., Falk, V., Meyns, B., Faerber, G., Pacini, D. & Potapov, E. Eur J Cardiothorac Surg (2023).  

Multiple pkd and piezo gene family members are required for atrioventricular valve formation.Juan, T., Ribeiro da Silva, A., Cardoso, B., Lim, S., Charteau, V. & Stainier, D. Y. R. Nat Commun 14, 214 (2023).  

Diabetes, Sports and Exercise. Esefeld, K., Kress, S., Behrens, M., Zimmer, P., Stumvoll, M., Thurm, U., Gehr, B., Halle, M. & Brinkmann, C. Exp Clin Endocrinol Diabetes (2023).  

Genome-wide association studies of cardiovascular disease. Walsh, R., Jurgens, S. J., Erdmann, J. & Bezzina, C. R. Physiol Rev (2023).    

Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro. Sych, K., Nold, S. P., Pfeilschifter, J., Vutukuri, R., Meisterknecht, J., Wittig, I., Frank, S. & Goren, I. J Mol Med (Berl) (2023).  

Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid. Silva, R. V., Biskup, K., Zabala-Jouvin, J. K., Batzdorf, C. S., Stellmach, C., Morr, A. S., Sack, I., Ludwig, A., Blanchard, V. & Infante-Duarte, C. Int J Biol Macromol 230, 123214 (2023).  

Effect of Spironolactone on QRS Duration in Patients at Risk for Heart Failure (from the HOMAGE Trial). Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Rossignol, P. & Zannad, F. Am J Cardiol 191, 39-42 (2023).  

Prevalence of peripheral arterial disease, abdominal aortic aneurysm, and risk factors in the Hamburg City Health Study: A Cross-Sectional Analysis. Behrendt, C. A., Thomalla, G., Rimmele, D. L., Petersen, E. L., Twerenbold, R., Debus, E. S., Kolbel, T., Blankenberg, S., Schmidt-Lauber, C., Peters, F. & Zyriax, B. C. Eur J Vasc Endovasc Surg (2023).    

Characterisation of patients referred to a tertiary-level inherited cardiac condition clinic with suspected arrhythmogenic right ventricular cardiomyopathy (ARVC). Aljehani, A., Kew, T., Baig, S., Cox, H., Sommerfeld, L. C., Ensam, B., Kalla, M., Steeds, R. P. & Fabritz, L. BMC Cardiovasc Disord 23, 14 (2023).  

In-Hospital ECG Findings, Changes in Medical Management, and Cardiovascular Outcomes in Patients With Acute Stroke or Transient Ischemic Attack. Olma, M. C., Tutuncu, S., Fiessler, C., Kunze, C., Kramer, M., Steindorf-Sabath, L., Jawad-Ul-Qamar, M., Kirchhof, P., Laufs, U., Schurig, J., Kraft, P., Rother, J., Gunther, A., Thomalla, G., Dimitrijeski, B., Nabavi, D. G., Veltkamp, R., Heuschmann, P. U., Haeusler, K. G., Endres, M. et al. J Am Heart Assoc 12, e027149 (2023).  

Tryptophan catabolites and depression in the general population: results from the Gutenberg Health Study. Michal, M., Schulz, A., Wild, P. S., Koeck, T., Munzel, T., Schuster, A. K., Strauch, K., Lackner, K., Sussmuth, S. D., Niessen, H. G., Borta, A., Allers, K. A., Zahn, D. & Beutel, M. E. BMC Psychiatry 23, 27 (2023).  

Thrombosis and Haemostasis 2022 Editors' Choice Papers. Weber, C., Blanchet, X. & Lip, G. Y. H. Thromb Haemost 123, 123-130 (2023).  

Disease- and sex-specific differences in patients with heart valve disease: a proteome study. Nordmeyer, S., Kraus, M., Ziehm, M., Kirchner, M., Schafstedde, M., Kelm, M., Niquet, S., Stephen, M. M., Baczko, I., Knosalla, C., Schapranow, M. P., Dittmar, G., Gotthardt, M., Falcke, M., Regitz-Zagrosek, V., Kuehne, T. & Mertins, P. Life Sci Alliance 6 (2023).  

A Happy New Year 2023 from Thrombosis and Haemostasis. Lip, G. Y. H., Rigby, A. & Weber, C. Thromb Haemost 123, 1-5 (2023).  

Long-term efficacy and safety of inclisiran in patients with high cardiovascular risk and elevated LDL cholesterol (ORION-3): results from the 4-year open-label extension of the ORION-1 trial. Ray, K. K., Troquay, R. P. T., Visseren, F. L. J., Leiter, L. A., Scott Wright, R., Vikarunnessa, S., Talloczy, Z., Zang, X., Maheux, P., Lesogor, A. & Landmesser, U. Lancet Diabetes Endocrinol 11, 109-119 (2023).  

A Tedious Journey: Cardiomyocyte Proliferation Requires More Than S-Phase Entry and Loss of Polyploidization. Ding, D. & Braun, T. Circulation 147, 154-157 (2023).  

"Very low attenuated plaque on CT appearing as a cyst-like structure in IVUS". Abdelwahed, Y. S., Siegrist, P. T., Skurk, C. & Landmesser, U. Int J Cardiovasc Imaging (2023).  

Lower Aldosterone Concentrations are Associated with a Smaller and Thinner Heart in the General Population - The Study of Health in Pomerania (SHIP). Santana, C. C., Hannemann, A., Ittermann, T., Gross, S., Pierdant, G., Schielke, J., Bahls, M., Volzke, H., Friedrich, N., Felix, S. B., Steinhagen-Thiessen, E., Dorr, M. & Markus, M. R. P. Eur J Prev Cardiol (2023).  

Innate Immunity in Cardiovascular Diseases-Identification of Novel Molecular Players and Targets. Poller, W., Heidecker, B., Ammirati, E., Kuss, A. W., Tzvetkova, A., Poller, W. C., Skurk, C. & Haghikia, A. J Clin Med 12 (2023).  

Heparin-Induced Thrombocytopenia in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation. Lusebrink, E., Scherer, C., Binzenhofer, L., Hoffmann, S., Hopler, J., Kellnar, A., Thienel, M., Joskowiak, D., Peterss, S., Petzold, T., Deseive, S., Hein, R., Brunner, S., Kaab, S., Braun, D., Theiss, H., Hausleiter, J., Hagl, C., Massberg, S. & Orban, M. J Clin Med 12 (2023).  

Anxiety and Depression Levels in Parents after Counselling for Fetal Heart Disease. Erbas, G. S., Herrmann-Lingen, C., Ostermayer, E., Kovacevic, A., Oberhoffer-Fritz, R., Ewert, P. & Wacker-Gussmann, A. J Clin Med 12 (2023).  

Exploring the incremental utility of circulating biomarkers for robust risk prediction of incident atrial fibrillation in European cohorts using regressions and modern machine learning methods. Toprak, B., Brandt, S., Brederecke, J., Gianfagna, F., Vishram-Nielsen, J. K. K., Ojeda, F. M., Costanzo, S., Borschel, C. S., Soderberg, S., Katsoularis, I., Camen, S., Vartiainen, E., Donati, M. B., Kontto, J., Bobak, M., Mathiesen, E. B., Linneberg, A., Koenig, W., Lochen, M. L., Di Castelnuovo, A. et al. Europace (2023).  

Generation of two CRISPR/Cas edited human induced pluripotent stem cell lines (DHMi005-A-3 and DHMi005-A-4) carrying a FLAG-tag after exon 9 of the TBX5 gene. Lahm, H., Stieglbauer, S., Neb, I., Doppler, S. A., Schneider, S., Dzilic, E., Lange, R., Krane, M. & Dressen, M. Stem Cell Res 66, 103011 (2023).  

Powered tooth brushes are beneficial for long-term oral health: Results from the Study of Health in Pomerania (SHIP-TREND). Sager, P., Kocher, T., Pitchika, V., Samietz, S., Volzke, H., Walter, C. & Holtfreter, B. J Clin Periodontol (2023).  

The gut microbiota in multiple sclerosis varies with disease activity. Thirion, F., Sellebjerg, F., Fan, Y., Lyu, L., Hansen, T. H., Pons, N., Levenez, F., Quinquis, B., Stankevic, E., Sondergaard, H. B., Dantoft, T. M., Poulsen, C. S., Forslund, S. K., Vestergaard, H., Hansen, T., Brix, S., Oturai, A., Sorensen, P. S., Ehrlich, S. D. & Pedersen, O. Genome Med 15, 1 (2023).  

Abnormalities in pulmonary function and volumes in patients with CHD?: a systematic review. Hock, J., Willinger, L., Pozza, R. D., Ewert, P. & Hager, A. Cardiol Young, 1-13 (2023).  

Risk prediction of atrial fibrillation and its complications in the community using hs troponin I. Borschel, C. S., Geelhoed, B., Niiranen, T., Camen, S., Donati, M. B., Havulinna, A. S., Gianfagna, F., Palosaari, T., Jousilahti, P., Kontto, J., Vartiainen, E., Ojeda, F. M., den Ruijter, H. M., Costanzo, S., de Gaetano, G., Di Castelnuovo, A., Linneberg, A., Vishram-Nielsen, J. K., Lochen, M. L., Koenig, W. et al. Eur J Clin Invest, e13950 (2023).  

Little at a time: trying to understand the battery of benefits of sodium-glucose contransporter 2 inhibitors in heart failure. von Haehling, S., Sato, R., Butler, J. & Anker, S. D. Eur J Heart Fail (2023).  

Biomarker signature and pathophysiological pathways in patients with chronic heart failure and metabolic syndrome. van der Hoef, C. C. S., Boorsma, E. M., Emmens, J. E., van Essen, B. J., Metra, M., Ng, L. L., Anker, S. D., Dickstein, K., Mordi, I. R., Dihoum, A., Lang, C. C., van Veldhuisen, D. J., Lam, C. S. P. & Voors, A. A. Eur J Heart Fail (2023).  

The neurovasculature as a target in temporal lobe epilepsy. Reiss, Y., Bauer, S., David, B., Devraj, K., Fidan, E., Hattingen, E., Liebner, S., Melzer, N., Meuth, S. G., Rosenow, F., Ruber, T., Willems, L. M. & Plate, K. H. Brain Pathol, e13147 (2023).  

Transcatheter edge-to-edge repair for secondary mitral regurgitation with third-generation devices in heart failure patients - results from the Global EXPAND Post-Market study. Orban, M., Rottbauer, W., Williams, M., Mahoney, P., von Bardeleben, R. S., Price, M. J., Grasso, C., Lurz, P., Zamorano, J. L., Asch, F. M., Maisano, F., Kar, S. & Hausleiter, J. Eur J Heart Fail (2023).  

Characterization of the Remote Noninfarcted Myocardium by Cardiac Magnetic Resonance for Postinfarction Risk Prediction: Ready for Primetime? Eitel, I. & Stiermaier, T. JACC Cardiovasc Imaging16, 60-62 (2023).  

Inappropriate Shock Rates and Long-Term Complications due to Subcutaneous Implantable Cardioverter Defibrillators in Patients With and Without Heart Failure: Results From a Multicenter, International Registry. Schiavone, M., Gasperetti, A., Laredo, M., Breitenstein, A., Vogler, J., Palmisano, P., Gulletta, S., Pignalberi, C., Lavalle, C., Pisano, E., Ricciardi, D., Curnis, A., Dello Russo, A., Tondo, C., Badenco, N., Di Biase, L., Kuschyk, J., Biffi, M., Tilz, R., Forleo, G. B. et al. Circ Arrhythm Electrophysiol 16, e011404 (2023).  

Longitudinal In Vivo Monitoring of Atheroprogression in Hypercholesterolemic Mice Using Photoacoustic Imaging. Ferraro, B., Giustetto, P., Schengel, O., Weckbach, L. T., Maegdefessel, L. & Soehnlein, O. Thromb Haemost (2023).  

Impact of diastolic pulmonary gradient and pulmonary artery pulse index on outcomes in heart transplant patients-Results from the Eurotransplant database. Wagner, T., Magnussen, C., Bernhardt, A., Smits, J. M., Steinbach, K., Reichenspurner, H., Kirchhof, P. & Grahn, H. Front Cardiovasc Med 9, 1036547 (2022).  

The year in cardiovascular medicine 2022: the top 10 papers in interventional cardiology. Barbato, E., McEntegart, M. & Gori, T. Eur Heart J 44, 259-261 (2023).

The challenge of managing patients with coronary and peripheral arterial disease - The ridge walk between bleeding and ischaemia. Doldi, P. M. & Deseive, S. Int J Cardiol 376, 24-25 (2023).