News

How the heart maintains its shape and function – and what can go wrong

A team from the DZHK sites in Heidelberg/Mannheim and Berlin has discovered that a single enzyme in the heart plays a key role in determining whether…

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New Reference Map Reveals How Cells Interact in Heart Failure

When the heart loses its pumping power, it’s not just the heart muscle that changes—entire tissue structures are affected. Numerous cell types respond…

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Cystine metabolism: key to vascular regeneration in ageing and injury

The uptake and oxidative degradation of cystine in the cell nucleus promote the growth and repair of blood vessels via nutrient-dependent histone…

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Lipids as key factors in cardiovascular disease

Lipids are not just energy sources and structural components of cell membranes – they also act as molecules that transmit signals within and between…

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As blood vessels age, so does the heart

New study shows where the crucial changes associated with ageing take place in heart tissue.

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The secret of muscle regeneration: the intact cell nucleus

Muscle stem cells ensure repair of muscles after injury a person's lifetime. This ability relies on the stability of the cells themselves. Scientists…

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A potential drug for treating stiff hearts

Michael Gotthardt (DZHK PI) at the Max Delbrück Center and collaborators are developing a drug to treat a common type of heart failure characterized…

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DZHK researchers receive funding from the German Heart Foundation

Five members of the German Centre for Cardiovascular Research (DZHK) are among the twelve researchers who have been awarded a total of over one…

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Genetic changes in the blood – a new risk factor for heart patients

A large study in the European Heart Journal shows that ‘clonal haematopoiesis of indeterminate potential’ (CHIP) is widespread in coronary heart…

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How our genes influence metabolism

Metabolism is as unique as a fingerprint. A better understanding of genetic influences could enable new therapies. Researchers at the Berlin Institute…

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