Prof. Dr. Christoph Knosalla

Research areas: heart transplantation, heart surgery, heart failure

• Cardiac MRI&CT Update2013 Poster Award bronze (Senior author, 2015)
• American Association of Thoracic Surgeons (Member, 2014)
• Cardiac MRI&CT Update2013 Poster Award silver (Senior author, 2013)
• Finalist Philip K. Caves Award-International Society for Heart and Lung Transplantation (Senior author, 2009)
• Hancock Research Award – German Society of Thoracic and Cardiovascular Surgery (2006)
• Finalist Poster Award der German Society of Transplantation Medicine (2002)
• Travel Grant der American Society of Transplantation „Fellows Symposium 2001“ (2001)
• Travel Grant der International Xenotransplantation  Association „VI Congress of the International Xenotransplantation Association 2001“ (2001)
• Young Investigator Award International Xenotransplantation Association (Co-author, 2001)
• Young Investigator Award der American Society of Transplantation (Co-author, 2001)
• Research fellowship of the Deutsche Forschungsgemeinschaft (2000-2002)
• Rudolf Stich Award – German Society of Thoracic and Cardiovascular Surgery (1998)
• Fellowship of the Airlift Memorial Fundation (Stiftung Luftbrückendank, 1996)
• Honorable mention „Young Investigator Award 1991“ - North American Society of Pacing and Electrophysiology (results of the MD-Thesis, 1991)

[Translate to English:] Hegemann N, Sang P, Kim JH, Kocana C, Momin N, Klages J, Kucherenko MM, Knosalla C, O'Brien B, Simmons S, Nahrendorf M, Kuebler WM and Grune J. Ultrasonographic assessment of pulmonary and Central venous congestion in experimental heart failure. Am J Physiol Heart Circ Physiol. 2024;326:H433-H440. PMID: 38099848

Kucherenko MM, Sang P, Yao J, Gransar T, Dhital S, Grune J, Simmons S, Michalick L, Wulsten D, Thiele M, Shomroni O, Hennig F, Yeter R, Solowjowa N, Salinas G, Duda GN, Falk V, Vyavahare NR, Kuebler WM and Knosalla C. Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease. Nat Commun. 2023;14:4416. PMID: 37479718

Solowjowa N, Nemchyna O, Hrytsyna Y, Meyer A, Hennig F, Falk V and Knosalla C. Surgical Restoration of Antero-Apical Left Ventricular Aneurysms: Cardiac Computed Tomography for Therapy Planning. Front Cardiovasc Med. 2022;9:763073. PMID: 35419444

Nemchyna O, Solowjowa N, Dandel M, Hrytsyna Y, Stein J, Knierim J, Schoenrath F, Hennig F, Falk V and Knosalla C. Predictive Value of Two-Dimensional Speckle-Tracking Echocardiography in Patients Undergoing Surgical Ventricular Restoration. Front Cardiovasc Med. 2022;9:824467. PMID: 35387444

von Haehling S, Birner C, Dworatzek E, Frantz S, Hellenkamp K, Israel CW, Kempf T, Klein HH, Knosalla C, Laufs U, Raake P, Wachter R and Hasenfuss G. Travelling with heart failure: risk assessment and practical recommendations. Nat Rev Cardiol. 2022;19:302-313. PMID: 34992256

Ullah I, Busch JF, Rabien A, Ergun B, Stamm C, Knosalla C, Hippenstiel S, Reinke P and Kurtz A. Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC-Derived Embryonic Stage Mesodermal Precursor Cells. Adv Sci (Weinh). 2020;7. PMID: 32154066

van Heesch S, Witte F, Schneider-Lunitz V, Schulz JF, Adami E, Faber AB, Kirchner M, Maatz H, Blachut S, Sandmann CL, Kanda M, Worth CL, Schafer S, Calviello L, Merriott R, Patone G, Hummel O, Wyler E, Obermayer B, Mucke MB, Lindberg EL, Trnka F, Memczak S, Schilling M, Felkin LE, Barton PJR, Quaife NM, Vanezis K, Diecke S, Mukai M, Mah N, Oh SJ, Kurtz A, Schramm C, Schwinge D, Sebode M, Harakalova M, Asselbergs FW, Vink A, de Weger RA, Viswanathan S, Widjaja AA, Gartner-Rommel A, Milting H, Dos Remedios C, Knosalla C, Mertins P, Landthaler M, Vingron M, Linke WA, Seidman JG, Seidman CE, Rajewsky N, Ohler U, Cook SA and Hubner N. The Translational Landscape of the Human Heart. Cell. 2019;178:242-260 e29. PMID: 31155234

Goldenberg NM, Hu Y, Hu X, Volchuk A, Zhao YD, Kucherenko MM, Knosalla C, de Perrot M, Tracey KJ, Al-Abed Y, Steinberg BE and Kuebler WM. Therapeutic Targeting of High-Mobility Group Box-1 in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2019;199:1566-1569.

Bacher P, Hohnstein T, Beerbaum E, Rocker M, Blango MG, Kaufmann S, Rohmel J, Eschenhagen P, Grehn C, Seidel K, Rickerts V, Lozza L, Stervbo U, Nienen M, Babel N, Milleck J, Assenmacher M, Cornely OA, Ziegler M, Wisplinghoff H, Heine G, Worm M, Siegmund B, Maul J, Creutz P, Tabeling C, Ruwwe-Glosenkamp C, Sander LE, Knosalla C, Brunke S, Hube B, Kniemeyer O, Brakhage AA, Schwarz C and Scheffold A. Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans. Cell. 2019;176:1340-1355 e15. PMID: 30799037

Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos Diez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Leseche G, Thomas P, Tudorache I, Kuhn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calabrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A and Ardehali A. Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study. Lancet Respir Med. 2018;6:357-367. PMID: 29650408

Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kroller-Schon S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Munzel T and Daiber A. CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice. Cardiovasc Res. 2018;114:312-323. PMID: 29036612