All research projects that work with data and biosamples from the DZHK Heart Bank and that have been approved to date can be found here. You can search for the resource you are using or do a full text search.
A genomic perspective on the spread of farming to Germany
The adoption of farming by Neolithic populations is one of the most dramatic and influential ecological shifts in the recent history of our species. Recent ancient DNA (aDNA) studies have clarified longstanding questions concerning the Neolithization of Western Eurasia. By sequencing the genomes of early farmers ...
Proteomic exploration of disease mechanisms related to the novel biomarker CCN1 for prediction of death in patients with dilated cardiomyopathy
Phenotyping in heart failure using a proteomic approach constitutes the next frontier and may enable the identification of novel biomarkers and new therapeutic targets.
Epigenetic and RNA-based biomarker validation in Cardiomypathies
Diseases of the heart muscle (cardiomyopathies) are common heart diseases that often have a severe course, up to and including heart failure.
Proteogenomic discovery of endothelium-derived microproteins in cardiovascular disease
Cardiac disease causative mutations in the Eph/ephrin signalling pathway
This project will study patients with dilated or hypertrophic cardiomyopathy that present mutations in the Eph/ephrin signaling pathway.
Identification of circulatory proteins reflecting myocardial processes relevant to disease progression in heart failure
The role of urinary Dickkopf-3 in cardiorenal syndrome
Impaired renal function is common in patients with heart failure. Up to 50 percent of patients show chronic kidney disease (CKD), associated with worse outcomes and complicates pharmacological management.
Computational assessment of genetic regulatory effects on RNA life using the DZHK OMICS resource
Characterisation and risk stratification of patient subgroups in dilated cardiomyopathy by utilisation of an inflammatory 47-plex-biomarker panel
Methylation profile of circulating cell-free DNA as a diagnostic tool for heart disease stratification
Characterization of lipidome dynamics in anthracycline-induced cardiotoxicity
Discovery and systematical characterization of Splicing Variation in Coronary Artery Disease
Genome-wide association studies (GWAS) have successfully identified over 300 gene loci contributing to the risk of coronary artery disease (CAD).
No entries found for search criteria