Publications 2022
Here you will find publications of the DZHK in chronological order. First authors in grey are members of the Young DZHK. For more publications, please also check out the websites of the individual research institutions that participate in the DZHK.
Januar
Paper of the Month
Association of renin and aldosterone with glucose metabolism in a Western European population: the KORA F4/FF4 study. Then, C., Ritzel, K., Herder, C., Then, H., Sujana, C., Heier, M., Meisinger, C., Peters, A., Koenig, W., Rathmann, W., Roden, M., Maalmi, H., Stumvoll, M., Meitinger, T., Bidlingmaier, M., Seissler, J., Thorand, B. & Reincke, M. BMJ Open Diabetes Res Care 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35086943
Intraocular Pressure and Its Relation to Ocular Geometry: Results From the Gutenberg Health Study. Hoffmann, E. M., Aghayeva, F., Wagner, F. M., Fiess, A., Nagler, M., Munzel, T., Wild, P. S., Beutel, M. E., Schmidtmann, I., Lackner, K. J., Pfeiffer, N. & Schuster, A. K. Invest Ophthalmol Vis Sci 63, 40 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089330
Stroke and Thromboembolism in Patients with Heart Failure and Sinus Rhythm: A Matter of Risk Stratification? Rivas, A., Lauw, M. N., Schnabel, R. B., Crowther, M. & Van Spall, H. G. C. Thromb Haemost122, 871-878 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35045579
Thrombosis and Haemostasis 2021 Editors' Choice Papers. Weber, C., Rigby, A. & Lip, G. Y. H. Thromb Haemost 122, 163-170 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35038760
A Rollercoaster Plunge into 2022. Lip, G. Y. H., Rigby, A. & Weber, C. Thromb Haemost 122, 1-4 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35038759
Epigenetic scores for the circulating proteome as tools for disease prediction. Gadd, D. A., Hillary, R. F., McCartney, D. L., Zaghlool, S. B., Stevenson, A. J., Cheng, Y., Fawns-Ritchie, C., Nangle, C., Campbell, A., Flaig, R., Harris, S. E., Walker, R. M., Shi, L., Tucker-Drob, E. M., Gieger, C., Peters, A., Waldenberger, M., Graumann, J., McRae, A. F., Deary, I. J. et al. Elife 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35023833
Carbon-mixed dental cement for fixing fiber optic ferrules prevents visually triggered locomotive enhancement in mice upon optogenetic stimulation. Araragi, N., Alenina, N. & Bader, M. Heliyon 8, e08692 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35024491
Physical Performance and Non-Esterified Fatty Acids in Men and Women after Transcatheter Aortic Valve Implantation (TAVI). Hardrich, M., Haase-Fielitz, A., Fielitz, J., Boschmann, M., Pivovarova-Ramich, O., Pfeiffer, A. F. H., Rudovich, N., Weylandt, K. H. & Butter, C. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35011078
Risk prediction in patients with low-flow, low-gradient aortic stenosis and reduced ejection fraction undergoing TAVI. Ludwig, S., Gossling, A., Seiffert, M., Westermann, D., Sinning, J. M., Sugiura, A., Adam, M., Mauri, V., Frank, D., Seoudy, H., Rudolph, T., Potratz, M., Conradi, L. & Schofer, N. Open Heart9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34987075
[Care of adults with congenital heart diseases in Germany-Leading role by internal medicine specialists and general practitioners]. Kaemmerer, H., Freilinger, S., Neidenbach, R., Achenbach, S., Andonian, C., Ewert, P., de Haan, F., Nagdyman, N., Schelling, J., Hofbeck, M., Bauer, U., Huntgeburth, M. & Meinertz, T. Internist (Berl) 63, 95-102 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34985563
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function. Hawe, J. S., Wilson, R., Schmid, K. T., Zhou, L., Lakshmanan, L. N., Lehne, B. C., Kuhnel, B., Scott, W. R., Wielscher, M., Yew, Y. W., Baumbach, C., Lee, D. P., Marouli, E., Bernard, M., Pfeiffer, L., Matias-Garcia, P. R., Autio, M. I., Bourgeois, S., Herder, C., Karhunen, V. et al. Nat Genet 54, 18-29 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34980917
Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar-capillary barrier function during influenza infection. McGrath, J. J. C., Vanderstocken, G., Dvorkin-Gheva, A., Cass, S. P., Afkhami, S., Fantauzzi, M. F., Thayaparan, D., Reihani, A., Wang, P., Beaulieu, A., Shen, P., Morissette, M., Jimenez-Saiz, R., Revill, S. D., Tabuchi, A., Zabini, D., Lee, W. L., Richards, C. D., Miller, M. S., Ask, K. et al. Eur Respir J 60 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35058252
Access Route and Clinical Outcomes After Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndrome Undergoing Invasive Treatment Strategy. Hemetsberger, R., Richardt, G., Lahu, S., Valina, C., Menichelli, M., Abdelghani, M., Wohrle, J., Toelg, R., Witzenbichler, B., Mankerious, N., Liebetrau, C., Bernlochner, I., Hamm, C. W., Allali, A., Joner, M., Fusaro, M., Xhepa, E., Hapfelmeier, A., Kufner, S., Sager, H. B. et al. Cardiovasc Revasc Med 41, 122-128 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35045943
Redox Regulatory Changes of Circadian Rhythm by the Environmental Risk Factors Traffic Noise and Air Pollution. Daiber, A., Frenis, K., Kuntic, M., Li, H., Wolf, E., Kilgallen, A. B., Lecour, S., Van Laake, L. W., Schulz, R., Hahad, O. & Munzel, T. Antioxid Redox Signal (2022). https://www.ncbi.nlm.nih.gov/pubmed/35088601
Association of thyroid function with insulin resistance: data from two population-based studies. Spira, D., Buchmann, N., Dorr, M., Markus, M. R. P., Nauck, M., Schipf, S., Spranger, J., Demuth, I., Steinhagen-Thiessen, E., Volzke, H. & Ittermann, T. Eur Thyroid J 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35085102
Detection and analysis of cerebral aneurysms based on X-ray rotational angiography - the CADA 2020 challenge. Ivantsits, M., Goubergrits, L., Kuhnigk, J. M., Huellebrand, M., Bruening, J., Kossen, T., Pfahringer, B., Schaller, J., Spuler, A., Kuehne, T., Jia, Y., Li, X., Shit, S., Menze, B., Su, Z., Ma, J., Nie, Z., Jain, K., Liu, Y., Lin, Y. et al. Med Image Anal 77, 102333 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34998111
Pulsed-field ablation combined with ultrahigh-density mapping in patients undergoing catheter ablation for atrial fibrillation: Practical and electrophysiological considerations. Gunawardene, M. A., Schaeffer, B. N., Jularic, M., Eickholt, C., Maurer, T., Akbulak, R. O., Flindt, M., Anwar, O., Pape, U. F., Maasberg, S., Gessler, N., Hartmann, J. & Willems, S. J Cardiovasc Electrophysiol 33, 345-356 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34978360
Circulating Interleukin-6 Levels and Incident Ischemic Stroke: A Systematic Review and Meta-analysis of Prospective Studies. Papadopoulos, A., Palaiopanos, K., Bjorkbacka, H., Peters, A., de Lemos, J. A., Seshadri, S., Dichgans, M. & Georgakis, M. K. Neurology 98, e1002-e1012 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34969940
Right atriotomy closure with modified ventricular assist device ring. Lanmuller, P., Eulert-Grehn, J. J., Starck, C., Falk, V. & Potapov, E. J Card Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35094449
Evaluation of systemic inflammation in response to remote ischemic preconditioning in patients undergoing transcatheter aortic valve replacement (TAVR). Zhang, K., Troeger, W., Kuhn, M., Wiedemann, S., Ibrahim, K., Pfluecke, C., Sveric, K. M., Winzer, R., Fedders, D., Ruf, T. F., Strasser, R. H., Linke, A., Quick, S. & Heidrich, F. M. Rev Cardiovasc Med 23, 20 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092212
Human-Device Interaction in the Life Science Laboratory. Soldner, R., Rheinlander, S., Meyer, T., Olszowy, M. & Austerjost, J. Adv Biochem Eng Biotechnol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35091814
HFA-PEFF score: prognosis in patients with preserved ejection fraction after transcatheter aortic valve implantation. Seoudy, H., von Eberstein, M., Frank, J., Thomann, M., Puehler, T., Lutter, G., Lutz, M., Bramlage, P., Frey, N., Saad, M. & Frank, D. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092186
Generation of homozygous Nav1.8 knock-out iPSC lines by CRISPR Cas9 genome editing to investigate a potential new antiarrhythmic strategy. Maurer, W., Hartmann, N., Argyriou, L., Sossalla, S. & Streckfuss-Bomeke, K. Stem Cell Res 60, 102677 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092938
Progressive Hereditary Transthyretin-Related Amyloidosis (ATTRv) Aggravated by ATTR Wild-Type and Complement Activation. Mattig, I., Heidecker, B., Tschope, C., Messroghli, D., Eurich, D., Kleefeld, F., Gaedeke, J., Stenzel, W., Schmidt, H. H., Rocken, C., Knebel, F. & Hahn, K. J Neuropathol Exp Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092287
Controlled-Level EVERolimus in Acute Coronary Syndrome (CLEVER-ACS) - A phase II, randomized, double-blind, multi-center, placebo-controlled trial. Klingenberg, R., Stahli, B. E., Heg, D., Denegri, A., Manka, R., Kapos, I., von Eckardstein, A., Carballo, D., Hamm, C. W., Vietheer, J., Rolf, A., Landmesser, U., Mach, F., Moccetti, T., Jung, C., Kelm, M., Munzel, T., Pedrazzini, G., Raber, L., Windecker, S. et al. Am Heart J(2022). https://www.ncbi.nlm.nih.gov/pubmed/35092722
Motion-compensated fat-water imaging for 3D cardiac MRI at ultra-high fields. Dietrich, S., Aigner, C. S., Mayer, J., Kolbitsch, C., Schulz-Menger, J., Schaeffter, T. & Schmitter, S. Magn Reson Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35092090
Telemedical cardiac risk assessment by implantable cardiac monitors in patients after myocardial infarction with autonomic dysfunction (SMART-MI-DZHK9): a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial. Bauer, A., Sappler, N., von Stulpnagel, L., Klemm, M., Schreinlechner, M., Wenner, F., Schier, J., Al Tawil, A., Dolejsi, T., Krasniqi, A., Eiffener, E., Bongarth, C., Stuhlinger, M., Huemer, M., Gori, T., Wakili, R., Sahin, R., Schwinger, R., Lutz, M., Luik, A. et al. Lancet Digit Health 4, e105-e116 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35090674
A practical guide to setting up pig models for cardiovascular catheterization, electrophysiological assessment and heart disease research. Schuttler, D., Tomsits, P., Bleyer, C., Vlcek, J., Pauly, V., Hesse, N., Sinner, M., Merkus, D., Hamers, J., Kaab, S. & Clauss, S. Lab Anim (NY) 51, 46-67 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35087256
Accuracy and Acute Efficacy of the Novel Injection-Based Occlusion Algorithm in Cryoballoon Pulmonary Vein Isolation Guided by Dielectric Imaging. Rottner, L., Moser, F., Weimann, J., Moser, J., Schleberger, R., Lemoine, M., Munkler, P., Dinshaw, L., Risius, T., Kirchhof, P., Ouyang, F., Reissmann, B., Metzner, A. & Rillig, A. Circ Arrhythm Electrophysiol 15, e010174 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089058
Where the Action Is-Leukocyte Recruitment in Atherosclerosis. Mauersberger, C., Hinterdobler, J., Schunkert, H., Kessler, T. & Sager, H. B. Front Cardiovasc Med 8, 813984 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35087886
[Ocular manifestations in patients with COVID-19]. Hosel, K., von der Burchard, C., Schunk, D., Franzenburg, J., Bahmer, T., Frank, D., Dargvainiene, J. & Roider, J. B. Ophthalmologe, 1-6 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089415
Immune Mechanisms of Plaque Instability. Gerhardt, T., Haghikia, A., Stapmanns, P. & Leistner, D. M. Front Cardiovasc Med 8, 797046 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35087883
Social Equity in the Efficacy of Computer-Based and In-Person Brief Alcohol Interventions Among General Hospital Patients With At-Risk Alcohol Use: A Randomized Controlled Trial. Freyer-Adam, J., Baumann, S., Bischof, G., Staudt, A., Goeze, C., Gaertner, B. & John, U. JMIR Ment Health 9, e31712 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089156
Patterned Illumination Techniques in Optogenetics: An Insight Into Decelerating Murine Hearts. Diaz-Maue, L., Steinebach, J. & Richter, C. Front Physiol 12, 750535 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35087413
Serum creatinine baseline fluctuation and acute kidney injury after intravenous or intra-arterial contrast agent administration - an intraindividual comparison as part of a randomized controlled trial. Bosserdt, M., Martus, P., Tauber, R., Dreger, H., Dewey, M. & Schonenberger, E. Nephrol Dial Transplant (2022). https://www.ncbi.nlm.nih.gov/pubmed/35090035
Interpretation and actionability of genetic variants in cardiomyopathies: a position statement from the European Society of Cardiology Council on cardiovascular genomics. Arbustini, E., Behr, E. R., Carrier, L., van Duijn, C., Evans, P., Favalli, V., van der Harst, P., Haugaa, K. H., Jondeau, G., Kaab, S., Kaski, J. P., Kavousi, M., Loeys, B., Pantazis, A., Pinto, Y., Schunkert, H., Di Toro, A., Thum, T., Urtis, M., Waltenberger, J. et al. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35089333
Impact of inferior vena cava entry characteristics on tricuspid annular access during transcatheter interventions. Ranard, L. S., Vahl, T. P., Chung, C. J., Sadri, S., Khalique, O. K., Hamid, N., Nazif, T., George, I., Ng, V., Patel, A., Rezende, C. P., Reisman, M., Latib, A., Hausleiter, J., Sorajja, P., Bapat, V. N., Tang, G. H. L., Davidson, C. J., Zahr, F., Makkar, R. et al. Catheter Cardiovasc Interv (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084803
Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive Cardiology. Piepoli, M. F., Adamo, M., Barison, A., Bestetti, R. B., Biegus, J., Bohm, M., Butler, J., Carapetis, J., Ceconi, C., Chioncel, O., Coats, A., Crespo-Leiro, M. G., de Simone, G., Drexel, H., Emdin, M., Farmakis, D., Halle, M., Heymans, S., Jaarsma, T., Jankowska, E. et al. Eur J Prev Cardiol 29, 275-300 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35083485
Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells. Pavez-Giani, M. G. & Cyganek, L. Front Cell Dev Biol 9, 800529 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35083221
Optimization of contrast material administration for coronary CT angiography using a software-based test-bolus evaluation algorithm. Fischer, A. M., Decker, J. A., Schoepf, J., Varga-Szemes, A., Flohr, T., Schmidt, B., Gutjahr, R., Sahbaee, P., Giovagnoli, D. A., Emrich, T., Martinez, J. D., Lari, K. B., Bayer, R. R., 2nd & Martin, S. S. Br J Radiol, 20201456 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084228
Comparative analysis of common alignment tools for single-cell RNA sequencing. Bruning, R. S., Tombor, L., Schulz, M. H., Dimmeler, S. & John, D. Gigascience 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084033
Human engineered heart tissue transplantation in a guinea pig chronic injury model. von Bibra, C., Shibamiya, A., Geertz, B., Querdel, E., Kohne, M., Studemann, T., Starbatty, J., Schmidt, F. N., Hansen, A., Hiebl, B., Eschenhagen, T. & Weinberger, F. J Mol Cell Cardiol 166, 1-10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35081367
Cardiac fibroblast activation detected by (68)Gallium-FAPI-46 positron emission tomography-magnetic resonance imaging as a sign of chronic activity in cardiac sarcoidosis. Siebermair, J., Kessler, L., Kupusovic, J., Rassaf, T. & Rischpler, C. Eur Heart J Case Rep 6, ytac005 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35079689
Real-time radial tagging for quantification of left ventricular torsion. Mohammadi, E., Nasiraei-Moghaddam, A. & Uecker, M. Magn Reson Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35081262
Population-based cohort imaging: skeletal muscle mass by magnetic resonance imaging in correlation to bioelectrical-impedance analysis. Kiefer, L. S., Fabian, J., Rospleszcz, S., Lorbeer, R., Machann, J., Kraus, M. S., Fischer, M., Roemer, F., Rathmann, W., Meisinger, C., Heier, M., Nikolaou, K., Peters, A., Storz, C., Schlett, C. L. & Bamberg, F. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35080141
Medication for patient-athletes-the therapeutic use exemption procedure. Fiorentini, C., Esefeld, K. & Halle, M. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35080612
Trends and predictors of radiation exposure in percutaneous coronary intervention: the PROTECTION VIII study. Stocker, T. J., Abdel-Wahab, M., Mollmann, H., Deseive, S., Massberg, S. & Hausleiter, J. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/35076020
Evaluation of a rapid deployment prosthesis strategy for the treatment of aortic valve endocarditis. Belyaev, S., Herrmann, F. E. M., Dashkevich, A., Wenke, K., Vlachea, P., von der Linden, J., Banafsche, R., Hagl, C. & Juchem, G. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35076056
Myocardial Deformation in the Pediatric Age Group: Normal Values for Strain and Strain Rate Using 2D Magnetic Resonance Feature Tracking. Voges, I., Negwer, I., Caliebe, A., Boroni Grazioli, S., Daubeney, P. E. F., Uebing, A., Pennell, D. J. & Krupickova, S. J Magn Reson Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35072310
Prognostic value of beta-blocker doses in patients with ventricular tachyarrhythmias. Schupp, T., Ziyadova, S., Reinhardt, J., Sag, Y. U., von Zworowsky, M., Reiser, L., Abumayyaleh, M., Weidner, K., Saleh, A., Mashayekhi, K., Bertsch, T., Abba, M. L., Akin, I. & Behnes, M. Heart Vessels (2022). https://www.ncbi.nlm.nih.gov/pubmed/35072762
Exercise and Carotid Properties in the Young-The KiGGS-2 Study. Konigstein, K., Buschges, J. C., Sarganas, G., Krug, S., Neuhauser, H. & Schmidt-Trucksass, A. Front Cardiovasc Med 8, 767025 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35071349
A cytosolic disulfide bridge-supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A. Voss, M., Kleinau, G., Gimber, N., Janek, K., Bredow, C., Thery, F., Impens, F., Schmoranzer, J., Scheerer, P., Kloetzel, P. M. & Beling, A. FEBS J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35066984
Diagnostic Accuracy of High-Sensitive Troponin for the Identification of Myocardial Infarction in Patients Presenting with Acute Heart Failure. Ledwoch, J., Schneider, A., Leidgschwendner, K., Kraxenberger, J., Krauth, A., Schneider, V., Martens, E., Muller, A., Laugwitz, K. L. & Kupatt, C. J Emerg Med(2022). https://www.ncbi.nlm.nih.gov/pubmed/35065860
Cascaded neural network-based CT image processing for aortic root analysis. Kruger, N., Meyer, A., Tautz, L., Hullebrand, M., Wamala, I., Pullig, M., Kofler, M., Kempfert, J., Sundermann, S., Falk, V. & Hennemuth, A. Int J Comput Assist Radiol Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35066774
Disturbed lipid and amino acid metabolisms in COVID-19 patients. Masoodi, M., Peschka, M., Schmiedel, S., Haddad, M., Frye, M., Maas, C., Lohse, A., Huber, S., Kirchhof, P., Nofer, J. R. & Renne, T. J Mol Med (Berl), 1-14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35064792
Prognostic value of epicardial adipose tissue volume in combination with coronary plaque and flow assessment for the prediction of major adverse cardiac events. Brandt, V., Bekeredjian, R., Schoepf, U. J., Varga-Szemes, A., Emrich, T., Aquino, G. J., Decker, J., Bayer, R. R., 2nd, Ellis, L., Ebersberger, U. & Tesche, C. Eur J Radiol 148, 110157 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35063819
Tissue-specific multi-omics analysis of atrial fibrillation. Assum, I., Krause, J., Scheinhardt, M. O., Muller, C., Hammer, E., Borschel, C. S., Volker, U., Conradi, L., Geelhoed, B., Zeller, T., Schnabel, R. B. & Heinig, M. Nat Commun 13, 441 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35064145
Tissue Engineered Transcatheter Pulmonary Valved Stent Implantation: Current State and Future Prospect. Zhang, X., Puehler, T., Seiler, J., Gorb, S. N., Sathananthan, J., Sellers, S., Haneya, A., Hansen, J. H., Uebing, A., Muller, O. J., Frank, D. & Lutter, G. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35054905
Cardiohepatic Syndrome Is Associated With Poor Prognosis in Patients Undergoing Tricuspid Transcatheter Edge-to-Edge Valve Repair. Stolz, L., Orban, M., Besler, C., Kresoja, K. P., Braun, D., Doldi, P., Orban, M., Hagl, C., Rommel, K. P., Mayerle, J., Hausleiter, S., Low, K., Higuchi, S., Wild, M., Unterhuber, M., Massberg, S., Nabauer, M., Thiele, H., Lurz, P. & Hausleiter, J. JACC Cardiovasc Interv 15, 179-189 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35057989
Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study. Metzner, T., Leitner, D. R., Mellitzer, K., Beck, A., Sourij, H., Stojakovic, T., Reishofer, G., Marz, W., Landmesser, U., Scharnagl, H., Toplak, H. & Silbernagel, G. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35052871
Short-Term Treatment with Alirocumab, Flow-Dependent Dilatation of the Brachial Artery and Use of Magnetic Resonance Diffusion Tensor Imaging to Evaluate Vascular Structure: An Exploratory Pilot Study. Metzner, T., Leitner, D. R., Dimsity, G., Gunzer, F., Opriessnig, P., Mellitzer, K., Beck, A., Sourij, H., Stojakovic, T., Deutschmann, H., Marz, W., Landmesser, U., Brodmann, M., Reishofer, G., Scharnagl, H., Toplak, H. & Silbernagel, G. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35052831
Increased Salt Intake Decreases Diet-Induced Thermogenesis in Healthy Volunteers: A Randomized Placebo-Controlled Study. Mahler, A., Klamer, S., Maifeld, A., Bartolomaeus, H., Marko, L., Chen, C. Y., Forslund, S. K., Boschmann, M., Muller, D. N. & Wilck, N. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35057434
Association between thyroid function and assessment of hepatic fat and iron contents by magnetic resonance imaging. Ittermann, T., Khattak, R. M., Markus, M. R. P., Kuhn, J. P., Kromrey, M. L., Targher, G., Steveling, A., Nauck, M. & Volzke, H. Endocr Connect 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35060922
Biomarkers-in-Cardiology 8 RE-VISITED-Consistent Safety of Early Discharge with a Dual Marker Strategy Combining a Normal hs-cTnT with a Normal Copeptin in Low-to-Intermediate Risk Patients with Suspected Acute Coronary Syndrome-A Secondary Analysis of the Randomized Biomarkers-in-Cardiology 8 Trial. Giannitsis, E., Garfias-Veitl, T., Slagman, A., Searle, J., Muller, C., Blankenberg, S., von Haehling, S., Katus, H. A., Hamm, C. W., Huber, K., Vollert, J. O. & Mockel, M. Cells 11(2022). https://www.ncbi.nlm.nih.gov/pubmed/35053326
Aurora Kinase A Is Involved in Controlling the Localization of Aquaporin-2 in Renal Principal Cells. Baltzer, S., Bulatov, T., Schmied, C., Kramer, A., Berger, B. T., Oder, A., Walker-Gray, R., Kuschke, C., Zuhlke, K., Eichhorst, J., Lehmann, M., Knapp, S., Weston, J., von Kries, J. P., Sussmuth, R. D. & Klussmann, E. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35054947
Hybrid Surgery for Severe Mitral Valve Calcification: Limitations and Caveats for an Open Transcatheter Approach. Bagaev, E., Ali, A., Saha, S., Sadoni, S., Orban, M., Naebauer, M., Mehilli, J., Massberg, S., Oberbach, A. & Hagl, C. Medicina (Kaunas) 58 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35056401
Emerging Role of cAMP/AMPK Signaling. Aslam, M. & Ladilov, Y. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35053423
Exercise-dependent changes in ventricular-arterial coupling and aortopulmonary collateral flow in Fontan patients: a real-time CMR study. Latus, H., Hofmann, L., Gummel, K., Khalil, M., Yerebakan, C., Waschulzik, B., Schranz, D., Voges, I., Jux, C. & Reich, B. Eur Heart J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35045176
Association of Telomere Length With Risk of Disease and Mortality. Schneider, C. V., Schneider, K. M., Teumer, A., Rudolph, K. L., Hartmann, D., Rader, D. J. & Strnad, P. JAMA Intern Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35040871
Stepwise approach for diagnosis and management of Takotsubo syndrome with cardiac imaging tools. Santoro, F., Mallardi, A., Leopizzi, A., Vitale, E., Stiermaier, T., Trambaiolo, P., Di Biase, M., Eitel, I. & Brunetti, N. D. Heart Fail Rev (2022). https://www.ncbi.nlm.nih.gov/pubmed/35040000
MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium. Kremer, V., Bink, D. I., Stanicek, L., van Ingen, E., Gimbel, T., Hilderink, S., Gunther, S., Nossent, A. Y. & Boon, R. A. Sci Rep 12, 843 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35039572
Does Age Matter? Pulmonary Endarterectomy in the Elderly Patient with CTEPH. Wiedenroth, C. B., Bandorski, D., Ariobi, K., Ghofrani, H. A., Lankeit, M., Liebetrau, C., Pruefer, D., Mayer, E., Kriechbaum, S. D. & Guth, S. Thorac Cardiovasc Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35038757
Refining imaging tools to detect advanced fibrosis: could liver surface nodularity address an unmet need in the NAFLD epidemic? Schattenberg, J. M. & Emrich, T. Eur Radiol 32, 1757-1759 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35084517
Apolipoprotein E derived from CD11c(+) cells ameliorates atherosclerosis. Sauter, M., Sauter, R. J., Nording, H., Lin, C., Olbrich, M., Autenrieth, S., Gleissner, C., Thunemann, M., Otero, N., Lutgens, E., Aherrahrou, Z., Wolf, D., Zender, L., Meuth, S., Feil, R. & Langer, H. F. iScience 25, 103677 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35036868
Additive value of epicardial adipose tissue quantification to coronary CT angiography-derived plaque characterization and CT fractional flow reserve for the prediction of lesion-specific ischemia. Brandt, V., Decker, J., Schoepf, U. J., Varga-Szemes, A., Emrich, T., Aquino, G., Bayer, R. R., 2nd, Carson, L., Sullivan, A., Ellis, L., von Knebel Doeberitz, P. L., Ebersberger, U., Bekeredjian, R. & Tesche, C. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35037968
Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors. Becker, J., Stanifer, M. L., Leist, S. R., Stolp, B., Maiakovska, O., West, A., Wiedtke, E., Borner, K., Ghanem, A., Ambiel, I., Tse, L. V., Fackler, O. T., Baric, R. S., Boulant, S. & Grimm, D. Mol Ther (2022). https://www.ncbi.nlm.nih.gov/pubmed/35038579
Prognostic impact of high-sensitive troponin on 30-day mortality in patients with acute heart failure and different classes of left ventricular ejection fraction. Ledwoch, J., Kraxenberger, J., Krauth, A., Schneider, A., Leidgschwendner, K., Schneider, V., Muller, A., Laugwitz, K. L., Kupatt, C. & Martens, E. Heart Vessels (2022). https://www.ncbi.nlm.nih.gov/pubmed/35034171
Establishment of an induced pluripotent stem cell line DHMi005-A from a healthy male proband. Dressen, M., Luzius, T., Lahm, H., Neb, I., Doppler, S. A., Schneider, S., Dzilic, E., Lange, R. & Krane, M. Stem Cell Res 59, 102662 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35033855
A junctional cAMP compartment regulates rapid Ca(2+) signaling in atrial myocytes. Brandenburg, S., Pawlowitz, J., Steckmeister, V., Subramanian, H., Uhlenkamp, D., Scardigli, M., Mushtaq, M., Amlaz, S. I., Kohl, T., Wegener, J. W., Arvanitis, D. A., Sanoudou, D., Sacconi, L., Hasenfuss, G., Voigt, N., Nikolaev, V. O. & Lehnart, S. E. J Mol Cell Cardiol 165, 141-157 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35033544
Robustness of outcomes in trials evaluating sodium-glucose co-transporter 2 inhibitors for heart failure. Usman, M. S., Khan, M. S., Fonarow, G. C., Greene, S. J., Friede, T., Vaduganathan, M., Filippatos, G., Coats, A. J. S., Anker, S. D. & Butler, J. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35029056
Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations. Rhoden, A., Schulze, T., Pietsch, N., Christ, T., Hansen, A. & Eschenhagen, T. Am J Physiol Heart Circ Physiol 322, H373-H385 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35030072
[The new ESC guidelines 2021 on prevention of cardiovascular diseases : Appeal for prevention]. Fegers-Wustrow, I., Wimbauer, F. & Halle, M. Herz 47, 55-62 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35029736
Assessment of frailty prior to TAVI: Can it now be measured objectively? Renker, M. & Kim, W. K. Int J Cardiol 350, 104-105 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35026339
Endothelial Retargeting of AAV9 In Vivo. Bozoglu, T., Lee, S., Ziegler, T., Jurisch, V., Maas, S., Baehr, A., Hinkel, R., Hoenig, A., Hariharan, A., Kim, C. I., Decker, S., Sami, H., Koppara, T., Oellinger, R., Muller, O. J., Frank, D., Megens, R., Nelson, P., Weber, C., Schnieke, A. et al. Adv Sci (Weinh), e2103867 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35023328
Low cardiopulmonary fitness is associated with higher liver fat content and higher gamma-glutamyltransferase concentrations in the general population - "The Sedentary's Liver". Zinterl, I., Ittermann, T., Schipf, S., Gross, S., Anspieler, H., Kim, S., Ewert, R., Bulow, R., Kuhn, J. P., Lerch, M. M., Volzke, H., Felix, S. B., Bahls, M., Targher, G., Dorr, M. & Markus, M. R. P. Liver Int (2022). https://www.ncbi.nlm.nih.gov/pubmed/35020966
Acceptance and safety of femoral versus radial access for percutaneous coronary intervention (PCI): results from a large monitor-controlled German registry (QuIK). Reifart, J., Gohring, S., Albrecht, A., Haerer, W., Levenson, B., Ringwald, G., Gartner, P. & Reifart, N. BMC Cardiovasc Disord 22, 7 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35016644
Meconium Microbiome of Very Preterm Infants across Germany. Klopp, J., Ferretti, P., Meyer, C. U., Hilbert, K., Haiss, A., Marissen, J., Henneke, P., Hudalla, H., Pirr, S., Viemann, D., Zemlin, M., Forslund, S. K., Hartel, C., Bork, P., Gehring, S., Van Rossum, T. & and the, P. C. mSphere 7, e0080821 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35019670
Single-center experience of ultra-high-density mapping guided catheter ablation of focal atrial tachycardia. Kellnar, A., Fichtner, S., Mehr, M., Czermak, T., Sinner, M. F., Lackermair, K. & Estner, H. L. Clin Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35019172
MicroRNA-365 regulates human cardiac action potential duration. Esfandyari, D., Idrissou, B. M. G., Hennis, K., Avramopoulos, P., Dueck, A., El-Battrawy, I., Gruter, L., Meier, M. A., Nager, A. C., Ramanujam, D., Dorn, T., Meitinger, T., Hagl, C., Milting, H., Borggrefe, M., Fenske, S., Biel, M., Dendorfer, A., Sassi, Y., Moretti, A. et al. Nat Commun 13, 220 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35017523
Simultaneous [18F]fluoride and gadobutrol enhanced coronary positron emission tomography/magnetic resonance imaging for in vivo plaque characterization. Wurster, T. H., Landmesser, U., Abdelwahed, Y. S., Skurk, C., Morguet, A., Leistner, D. M., Frohlich, G., Haghikia, A., Engel, L. C., Schuster, A., Noutsias, M., Schulze, D., Hamm, B., Furth, C., Brenner, W., Botnar, R. M., Bigalke, B. & Makowski, M. R. Eur Heart J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35015852
Synthesis of C-Oligosaccharides through Versatile C(sp(3) )-H Glycosylation of Glycosides. Wu, J., Kopp, A. & Ackermann, L. Angew Chem Int Ed Engl, e202114993 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35015329
Skeletal muscle derived Musclin protects the heart during pathological overload. Szaroszyk, M., Kattih, B., Martin-Garrido, A., Trogisch, F. A., Dittrich, G. M., Grund, A., Abouissa, A., Derlin, K., Meier, M., Holler, T., Korf-Klingebiel, M., Volker, K., Garfias Macedo, T., Pablo Tortola, C., Boschmann, M., Huang, N., Froese, N., Zwadlo, C., Malek Mohammadi, M., Luo, X. et al. Nat Commun 13, 149 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35013221
Education and certification on heart failure of the Heart Failure Association of the European Society of Cardiology. Mullens, W., Coats, A., Seferovic, P., Metra, M., Mebazaa, A., Ruschitzka, F., Filippatos, G., Volterrani, M., Ponikowski, P., Jankowska, E. A., Chioncel, O., McDonagh, T. A., Piepoli, M. F., Milicic, D., Thum, T., Hill, L., Abdelhamid, M., Adamopoulos, S., Belenkov, Y., Gal, T. B. et al. Eur J Heart Fail(2022). https://www.ncbi.nlm.nih.gov/pubmed/35014132
Biodegradable Poly-epsilon-Caprolactone Scaffolds with ECFCs and iMSCs for Tissue-Engineered Heart Valves. Lutter, G., Puehler, T., Cyganek, L., Seiler, J., Rogler, A., Herberth, T., Knueppel, P., Gorb, S. N., Sathananthan, J., Sellers, S., Muller, O. J., Frank, D. & Haben, I. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35008953
Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients. Haberbosch, L., Maurer, L., Sandforth, A., Wernicke, C., Spranger, J., Mai, K. & Jumpertz von Schwartzenberg, R. Endocr Relat Cancer 29, 121-128 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35014973
[ESC guidelines 2021 on cardiac pacing and cardiac resynchronization therapy : What's new?]. Vogler, J., Keelani, A., Traub, A. & Tilz, R. R. Herz 47, 31-40 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35006289
The Role of Junctophilin Proteins in Cellular Function. Lehnart, S. E. & Wehrens, X. H. T. Physiol Rev(2022). https://www.ncbi.nlm.nih.gov/pubmed/35001666
First Transfemoral TAV-in-TAV Implantation of an ACURATE Neo2 Into a Degenerated Lotus Prosthesis. Kim, W. K., Charitos, E. I., Choi, Y. H. & Hamm, C. W. Can J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35007707
Sparse 3D contrast-enhanced whole-heart imaging for coronary artery evaluation. Ansari, U., Janssen, S., Baumann, S., Borggrefe, M., Waldeck, S., Schonberg, S., Papavassiliu, T. & Overhoff, D. Herz(2022). https://www.ncbi.nlm.nih.gov/pubmed/35006290
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart. van der Velden, J., Asselbergs, F. W., Bakkers, J., Batkai, S., Bertrand, L., Bezzina, C. R., Bot, I., Brundel, B., Carrier, L., Chamuleau, S., Ciccarelli, M., Dawson, D., Davidson, S. M., Dendorfer, A., Duncker, D. J., Eschenhagen, T., Fabritz, L., Falcao-Pires, I., Ferdinandy, P., Giacca, M. et al. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/34999816
Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme. Petersen, E. L., Gossling, A., Adam, G., Aepfelbacher, M., Behrendt, C. A., Cavus, E., Cheng, B., Fischer, N., Gallinat, J., Kuhn, S., Gerloff, C., Koch-Gromus, U., Harter, M., Hanning, U., Huber, T. B., Kluge, S., Knobloch, J. K., Kuta, P., Schmidt-Lauber, C., Lutgehetmann, M. et al.Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/34999762
Polygenic Risk Scores for Predicting Adverse Outcomes After Coronary Revascularization. Aittokallio, J., Kauko, A., Vaura, F., Salomaa, V., Kiviniemi, T., FinnGen, Schnabel, R. B. & Niiranen, T. Am J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/34998506
Effects of whole-body MRI on outpatient health service costs: a general-population prospective cohort study in Mecklenburg-Vorpommern, Germany. Schmidt, C. O., Sierocinski, E., Baumeister, S., Hegenscheid, K., Volzke, H. & Chenot, J. F. BMJ Open 12, e056572 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34996801
Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension. Dahale, S., Ruiz-Orera, J., Silhavy, J., Hubner, N., van Heesch, S., Pravenec, M. & Atanur, S. S. Life Sci Alliance5 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34996843
Travelling with heart failure: risk assessment and practical recommendations. von Haehling, S., Birner, C., Dworatzek, E., Frantz, S., Hellenkamp, K., Israel, C. W., Kempf, T., Klein, H. H., Knosalla, C., Laufs, U., Raake, P., Wachter, R. & Hasenfuss, G. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/34992256
Comparison of feasibility and results of frailty assessment methods prior to left ventricular assist device implantation. Roehrich, L., Sundermann, S. H., Just, I. A., Kopp Fernandes, L., Stein, J., Solowjowa, N., Mulzer, J., Mueller, M., Hummel, M., Knierim, J., Potapov, E., Falk, V. & Schoenrath, F. ESC Heart Fail(2022). https://www.ncbi.nlm.nih.gov/pubmed/34994094
The Gutenberg health study: a five-year prospective analysis of psychosocial working conditions using COPSOQ (Copenhagen psychosocial Questoinnaire) and ERI (effort-reward imbalance). Nuebling, M., Hegewald, J., Starke, K. R., Lincke, H. J., Jankowiak, S., Liebers, F., Latza, U., Letzel, S., Riechmann-Wolf, M., Gianicolo, E., Beutel, M., Pfeiffer, N., Lackner, K., Munzel, T., Wild, P. S. & Seidler, A. BMC Public Health 22, 24 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34991529
Management of patients with mitral regurgitation ineligible for standard therapy undergoing TMVI screening. Ludwig, S., Sedighian, R., Weimann, J., Koell, B., Waldschmidt, L., Schafer, A., Seiffert, M., Westermann, D., Reichenspurner, H., Blankenberg, S., Schofer, N., Lubos, E., Conradi, L. & Kalbacher, D. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/34992049
A Novel Transcatheter Heart Valve for an Overcrowded TAVR Market: What Should We Focus On?Lange, R. & Vitanova, K. JACC Cardiovasc Interv 15, 105-106 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34991815
Evidence-based cardiovascular magnetic resonance cost-effectiveness calculator for the detection of significant coronary artery disease. Pandya, A., Yu, Y. J., Ge, Y., Nagel, E., Kwong, R. Y., Bakar, R. A., Grizzard, J. D., Merkler, A. E., Ntusi, N., Petersen, S. E., Rashedi, N., Schwitter, J., Selvanayagam, J. B., White, J. A., Carr, J., Raman, S. V., Simonetti, O. P., Bucciarelli-Ducci, C., Sierra-Galan, L. M., Ferrari, V. A. et al. J Cardiovasc Magn Reson 24, 1 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34986851
Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome. Meier, A. B., Raj Murthi, S., Rawat, H., Toepfer, C. N., Santamaria, G., Schmid, M., Mastantuono, E., Schwarzmayr, T., Berutti, R., Cleuziou, J., Ewert, P., Gorlach, A., Klingel, K., Laugwitz, K. L., Seidman, C. E., Seidman, J. G., Moretti, A. & Wolf, C. M. iScience 25, 103596 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34988410
Left atrial strain predicts exercise capacity in heart failure independently of left ventricular ejection fraction. Maffeis, C., Rossi, A., Cannata, L., Zocco, C., Belyavskiy, E., Radhakrishnan, A. K., Feuerstein, A., Morris, D. A., Pieske-Kraigher, E., Pieske, B., Edelmann, F. & Temporelli, P. L. ESC Heart Fail(2022). https://www.ncbi.nlm.nih.gov/pubmed/34989138
Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study. Gar, C., Thorand, B., Herder, C., Sujana, C., Heier, M., Meisinger, C., Peters, A., Koenig, W., Rathmann, W., Roden, M., Stumvoll, M., Maalmi, H., Meitinger, T., Then, H., Seissler, J. & Then, C. PLoS One 17, e0262330 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34990470
Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure. Ceelen, D., Voors, A. A., Tromp, J., van Veldhuisen, D. J., Dickstein, K., de Boer, R. A., Lang, C. C., Anker, S. D., Ng, L. L., Metra, M., Ponikowski, P. & Figarska, S. M. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/34989084
Early benefit with empagliflozin in heart failure with preserved ejection fraction: insights from the EMPEROR-Preserved trial. Butler, J., Siddiqi, T. J., Filippatos, G., Ferreira, J. P., Pocock, S. J., Zannad, F. & Anker, S. D. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/34989083
"Precision-CT(O)": CTO-lesions unraveled by multimodality cardiac imaging. Abdelwahed, Y. S., Blum, E., Landmesser, U., Werner, G. S. & Leistner, D. M. Int J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/34982310
Implication of proliferation gene biomarkers in pulmonary hypertension. Yan, Y., Jiang, R., Yuan, P., Wen, L., Pang, X. B., Jing, Z. C., He, Y. Y. & Han, Z. Y. Animal Model Exp Med 4, 369-380 (2021). https://www.ncbi.nlm.nih.gov/pubmed/34977488
Anatomical suitability and off-label use of contemporary transcatheter heart valves. Werner, N., Renker, M., Dorr, O., Bauer, T., Nef, H., Choi, Y. H., Hamm, C. W., Zahn, R. & Kim, W. K. Int J Cardiol 350, 96-103 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34979147
State-of-the-art: Insights from the Ross Registry. Fujita, B., Aboud, A., Sievers, H. H. & Ensminger, S. JTCVS Tech 10, 396-400 (2021). https://www.ncbi.nlm.nih.gov/pubmed/34977764
The year in cardiovascular medicine 2021: interventional cardiology. Escaned, J., Jaffer, F. A., Mehilli, J. & Mehran, R. Eur Heart J 43, 377-386 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34974613
Circulating Interleukin-6 Levels and Incident Ischemic Stroke: A Systematic Review and Meta-analysis of Prospective Studies. Papadopoulos, A., Palaiopanos, K., Bjorkbacka, H., Peters, A., de Lemos, J. A., Seshadri, S., Dichgans, M. & Georgakis, M. K. Neurology (2021). https://www.ncbi.nlm.nih.gov/pubmed/34969940
Histopathology-Based Deep-Learning Predicts Atherosclerotic Lesions in Intravascular Imaging. Holmberg, O., Lenz, T., Koch, V., Alyagoob, A., Utsch, L., Rank, A., Sabic, E., Seguchi, M., Xhepa, E., Kufner, S., Cassese, S., Kastrati, A., Marr, C., Joner, M. & Nicol, P. Front Cardiovasc Med 8, 779807 (2021). https://www.ncbi.nlm.nih.gov/pubmed/34970608
PET/MR Technology: Advancement and Challenges. Bogdanovic, B., Solari, E. L., Villagran Asiares, A., McIntosh, L., van Marwick, S., Schachoff, S. & Nekolla, S. G. Semin Nucl Med (2021). https://www.ncbi.nlm.nih.gov/pubmed/34969520
Remote Speech Analysis in the Evaluation of Hospitalized Patients With Acute Decompensated Heart Failure. Amir, O., Abraham, W. T., Azzam, Z. S., Berger, G., Anker, S. D., Pinney, S. P., Burkhoff, D., Shallom, I. D., Lotan, C. & Edelman, E. R. JACC Heart Fail 10, 41-49 (2022). https://www.ncbi.nlm.nih.gov/pubmed/34969496
Februar
Paper of the Month
Transcriptional Alterations in X-Linked Dystonia-Parkinsonism Caused by the SVA Retrotransposon. Pozojevic, J., Algodon, S. M., Cruz, J. N., Trinh, J., Bruggemann, N., Lass, J., Grutz, K., Schaake, S., Tse, R., Yumiceba, V., Kruse, N., Schulz, K., Sreenivasan, V. K. A., Rosales, R. L., Jamora, R. D. G., Diesta, C. C. E., Matschke, J., Glatzel, M., Seibler, P., Handler, K. et al. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35216353
Induction of Hepatitis E Virus Anti-ORF3 Antibodies from Systemic Administration of a Muscle-Specific Adeno-Associated Virus (AAV) Vector. Maurer, L., El Andari, J., Rapti, K., Spreyer, L., Steinmann, E., Grimm, D. & Dao Thi, V. L. Viruses 14 (2022). www.ncbi.nlm.nih.gov/pubmed/35215859
Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration. Li, W., Luo, X., Poetsch, M. S., Oertel, R., Nichani, K., Schneider, M., Strano, A., Hasse, M., Steiner, R. P., Cyganek, L., Hettwer, K., Uhlig, S., Simon, K., Guan, K. & Schubert, M. Pharmaceuticals (Basel) 15 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35215332
Trends and Risk Factors of In-Hospital Mortality of Patients with COVID-19 in Germany: Results of a Large Nationwide Inpatient Sample. Hobohm, L., Sagoschen, I., Barco, S., Schmidtmann, I., Espinola-Klein, C., Konstantinides, S., Munzel, T. & Keller, K. Viruses 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35215869
Takotsubo Syndrome: Translational Implications and Pathomechanisms. Fan, X., Yang, G., Kowitz, J., Akin, I., Zhou, X. & El-Battrawy, I. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35216067
The Spontaneous Course of Human Herpesvirus 6 DNA-Associated Myocarditis and the Effect of Immunosuppressive Intervention. Elsanhoury, A., Kuhl, U., Stautner, B., Klein, O., Krannich, A., Morris, D., Willner, M., Jankowska, E., Klingel, K., Van Linthout, S. & Tschope, C. Viruses 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35215893
A Non-Canonical Link between Non-Coding RNAs and Cardiovascular Diseases. Natarelli, L. & Weber, C. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35203652
LMNA Mutation in a Family with a Strong History of Sudden Cardiac Death. Keil, L., Berisha, F., Knappe, D., Kubisch, C., Shoukier, M., Kirchhof, P., Fabritz, L., Hellenbroich, Y., Woitschach, R. & Magnussen, C. Genes (Basel) 13 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35205214
Depletion of Homeostatic Antibodies against Malondialdehyde-Modified Low-Density Lipoprotein Correlates with Adverse Events in Major Vascular Surgery. Hartley, A., Pradeep, M., Van den Berg, V., Khan, A. H. A., Shah, H. A., Allaf, M., Chow, A., Caga-Anan, M., Shalhoub, J., Koenig, W., Fisher, M., Haskard, D. O. & Khamis, R. Y. Antioxidants (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35204154
New Tricks with Old Dogs: Computational Identification and Experimental Validation of New miRNA-mRNA Regulation in hiPSC-CMs. Bencun, M., Britto-Borges, T., Eschenbach, J. & Dieterich, C. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35203600
Enhanced Cardiac CaMKII Oxidation and CaMKII-Dependent SR Ca Leak in Patients with Sleep-Disordered Breathing. Arzt, M., Drzymalski, M. A., Ripfel, S., Meindl, S., Biedermann, A., Durczok, M., Keller, K., Mustroph, J., Katz, S., Tafelmeier, M., Lebek, S., Florchinger, B., Camboni, D., Wittmann, S., Backs, J., Schmid, C., Maier, L. S. & Wagner, S. Antioxidants (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35204213
It Is Not Carved in Stone-The Need for a Genetic Reevaluation of Variants in Pediatric Cardiomyopathies. Westphal, D. S., Pollmann, K., Marschall, C., Wacker-Gussmann, A., Oberhoffer-Fritz, R., Laugwitz, K. L., Ewert, P. & Wolf, C. M. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35200695
Home-Based Long-Term Physical Endurance and Inspiratory Muscle Training for Children and Adults With Fontan Circulation-Initial Results From a Prospective Study. Dirks, S., Kramer, P., Schleiger, A., Speck, H. M., Wolfarth, B., Thouet, T., Berger, F., Sallmon, H. & Ovroutski, S. Front Cardiovasc Med 8, 784648 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35198605
Impact of the 2009 ESC Guideline Change on Surgically Treated Infective Endocarditis. Weber, C., Luehr, M., Petrov, G., Misfeld, M., Akhyari, P., Tugtekin, S. M., Diab, M., Saha, S., Elderia, A., Lichtenberg, A., Hagl, C., Doenst, T., Matschke, K., Borger, M. A. & Wahlers, T. Ann Thorac Surg 114, 1349-1356 (2022).
Pre-admission antiplatelet therapy and treatment effect of ticagrelor vs. prasugrel in patients with acute coronary syndromes-a subgroup analysis of the ISAR-REACT 5 trial. Lahu, S., Ndrepepa, G., Neumann, F. J., Menichelli, M., Bernlochner, I., Richardt, G., Wöhrle, J., Witzenbichler, B., Hemetsberger, R., Mayer, K., Akin, I., Cassese, S., Gewalt, S., Xhepa, E., Kufner, S., Valina, C., Sager, H. B., Joner, M., Ibrahim, T., Laugwitz, K. L. et al. Eur Heart J Cardiovasc Pharmacother 8, 687-694 (2022).
Interventional Procedures for Left Ventricular Assist Device-Associated Complications. Lanmueller, P., Eulert-Grehn, J. J., Unbehaun, A., Klein, C., Hommel, M., Kofler, M., Kempfert, J., Hoermandinger, C., Kaufmann, F., Stawowy, P., Dreysse, S., Mulzer, J., Mueller, M., Falk, V., Schoenrath, F., Potapov, E. & Just, I. A. ASAIO J 68, 1332-1338 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35184090
Changes in Endocan and Dermatan Sulfate Are Associated with Biomechanical Properties of Abdominal Aortic Wall during Aneurysm Expansion and Rupture. Metschl, S., Bruder, L., Paloschi, V., Jakob, K., Reutersberg, B., Reeps, C., Maegdefessel, L., Gee, M., Eckstein, H. H. & Pelisek, J. Thromb Haemost122, 1513-1523 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170008
The Role of Epigenetic Clocks in Explaining Educational Inequalities in Mortality: A Multicohort Study and Meta-analysis. Fiorito, G., Pedron, S., Ochoa-Rosales, C., McCrory, C., Polidoro, S., Zhang, Y., Dugue, P. A., Ratliff, S., Zhao, W. N., McKay, G. J., Costa, G., Solinas, M. G., Harris, K. M., Tumino, R., Grioni, S., Ricceri, F., Panico, S., Brenner, H., Schwettmann, L., Waldenberger, M. et al. J Gerontol A Biol Sci Med Sci77, 1750-1759 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35172329
Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide-Based Hybrid Compounds against SARS-CoV-2 and Cancer. Herrmann, L., Yaremenko, I. A., Çapcı, A., Struwe, J., Tailor, D., Dheeraj, A., Hodek, J., Belyakova, Y. Y., Radulov, P. S., Weber, J., Malhotra, S. V., Terent'ev, A. O., Ackermann, L. & Tsogoeva, S. B. ChemMedChem 17, e202200005 (2022).
Hypothalamic Galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop. Corradi, L., Bruzzone, M., Maschio, M. D., Sawamiphak, S. & Filosa, A. Curr Biol 32, 1497-1510 e1495 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35219430
Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial. Diab, M., Lehmann, T., Bothe, W., Akhyari, P., Platzer, S., Wendt, D., Deppe, A. C., Strauch, J., Hagel, S., Gunther, A., Faerber, G., Sponholz, C., Franz, M., Scherag, A., Velichkov, I., Silaschi, M., Fassl, J., Hofmann, B., Lehmann, S., Schramm, R. et al. Circulation 145, 959-968 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35213213
Redox-dependent loss of flavin by mitochondria complex I is different in brain and heart. Yoval-Sanchez, B., Ansari, F., James, J., Niatsetskaya, Z., Sosunov, S., Filipenko, P., Tikhonova, I. G., Ten, V., Wittig, I., Rafikov, R. & Galkin, A. Redox Biol 51, 102258 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35189550
A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome. Widjaja, A. A., Shekeran, S. G., Adami, E., Ting, J. G. W., Tan, J., Viswanathan, S., Lim, S. Y., Tan, P. H., Hubner, N., Coffman, T. & Cook, S. A. J Am Soc Nephrol 33, 718-730 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35140116
Computed tomographic assessment of right ventricular long axis strain for prognosis after transcatheter aortic valve replacement. Aquino, G. J., Decker, J. A., Schoepf, U. J., Carson, L., Fiegel, M., Paladugu, N., Brandt, V., Yacoub, B., Emrich, A. L., Kroencke, T., Burt, J. R., Bayer, R., 2nd, Emrich, T. & Varga-Szemes, A. Eur J Radiol 149, 110212 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35220197
Impact of the 2009 ESC Guideline Change on Surgically Treated Infective Endocarditis. Weber, C., Luehr, M., Petrov, G., Misfeld, M., Akhyari, P., Tugtekin, S. M., Diab, M., Saha, S., Elderia, A., Lichtenberg, A., Hagl, C., Doenst, T., Matschke, K., Borger, M. A., Wahlers, T. & Clinical, M. P. o. A. o. I. E. i. G. S. G. Ann Thorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35216990
Interferon-beta Suppresses Transcriptionally Active Parvovirus B19 Infection in Viral Cardiomyopathy: A Subgroup Analysis of the BICC-Trial. Schultheiss, H. P., Bock, C. T., Aleshcheva, G., Baumeier, C., Poller, W. & Escher, F. Viruses 14 (2022). www.ncbi.nlm.nih.gov/pubmed/35216037
A potential future Fontan modification: preliminary in vitro data of a pressure-generating tube from engineered heart tissue. Kohne, M., Behrens, C. S., Studemann, T., Bibra, C. V., Querdel, E., Shibamiya, A., Geertz, B., Olfe, J., Huners, I., Jockenhovel, S., Hubler, M., Eschenhagen, T., Sachweh, J. S., Weinberger, F. & Biermann, D. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35218664
Phenotypic spectrum of BLM- and RMI1-related Bloom syndrome. Gonenc, II, Elcioglu, N. H., Martinez Grijalva, C., Aras, S., Grossmann, N., Praulich, I., Altmuller, J., Kaulfuss, S., Li, Y., Nurnberg, P., Burfeind, P., Yigit, G. & Wollnik, B. Clin Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35218564
Symptom Severity and Health-Related Quality of Life in Patients with Atrial Fibrillation: Findings from the Observational ARENA Study. Sadlonova, M., Senges, J., Nagel, J., Celano, C., Klasen-Max, C., Borggrefe, M., Akin, I., Thomas, D., Schwarzbach, C. J., Kleeman, T., Schneider, S., Hochadel, M., Suselbeck, T., Schwacke, H., Alonso, A., Haass, M., Ladwig, K. H. & Herrmann-Lingen, C. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35207412
Improving adaptive seamless designs through Bayesian optimization. Richter, J., Friede, T. & Rahnenfuhrer, J. Biom J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35212423
Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel. Puccini, M., Rauch, C., Jakobs, K., Friebel, J., Hassanein, A., Landmesser, U. & Rauch, U. Cardiovasc Drugs Ther (2022). https://www.ncbi.nlm.nih.gov/pubmed/35211819
Of hypes and paradigms in the search of the ideal valved conduit in the young. Peterss, S., Hagl, C. & Pichlmaier, M. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35213693
Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells. Muller, N., Warwick, T., Noack, K., Malacarne, P. F., Cooper, A. J. L., Weissmann, N., Schroder, K., Brandes, R. P. & Rezende, F. Antioxidants (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35204316
Intracranial haemorrhage in adult patients on venoarterial extracorporeal membrane oxygenation. Lusebrink, E., Zimmer, S., Schrage, B., Dabboura, S., Majunke, N., Scherer, C., Aksoy, A., Krogmann, A., Hoffmann, S., Szczanowicz, L., Binzenhofer, L., Peterss, S., Kuhn, C., Hagl, C., Massberg, S., Schafer, A., Thiele, H., Westermann, D., Orban, M. & Group, I.-V.-E. I. Eur Heart J Acute Cardiovasc Care(2022). https://www.ncbi.nlm.nih.gov/pubmed/35213724
Polygenic risk score: a tool ready for clinical use? Kavousi, M. & Schunkert, H. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35211747
Polycystic ovarian syndrome increases prevalence of concentric hypertrophy in normotensive obese women. De Jong, K. A., Berisha, F., Naderpoor, N., Appelbe, A., Kotowicz, M. A., Cukier, K., McGee, S. L. & Nikolaev, V. O. PLoS One 17, e0263312 (2022).
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Barc, J., Tadros, R., Glinge, C., Chiang, D. Y., Jouni, M., Simonet, F., Jurgens, S. J., Baudic, M., Nicastro, M., Potet, F., Offerhaus, J. A., Walsh, R., Choi, S. H., Verkerk, A. O., Mizusawa, Y., Anys, S., Minois, D., Arnaud, M., Duchateau, J., Wijeyeratne, Y. D.et al. Nat Genet 54, 232-239 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35210625
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection. Pekayvaz, K., Leunig, A., Kaiser, R., Joppich, M., Brambs, S., Janjic, A., Popp, O., Nixdorf, D., Fumagalli, V., Schmidt, N., Polewka, V., Anjum, A., Knottenberg, V., Eivers, L., Wange, L. E., Gold, C., Kirchner, M., Muenchhoff, M., Hellmuth, J. C., Scherer, C. et al. Nat Commun 13, 1018 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35197461
Influence of ejection fraction on biomarker expression and response to spironolactone in people at risk of heart failure: findings from the HOMAGE trial. Ferreira, J. P., Verdonschot, J. A. J., Girerd, N., Bozec, E., Pellicori, P., Collier, T., Mariottoni, B., Cosmi, F., Hazebroek, M., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelman, F., Clark, A. L., Diez, J., Gonzalez, A., Rossignol, P., Cleland, J. G. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35199421
Percutaneous coronary intervention for chronic total occlusion in octogenarians: a propensity score study. Blessing, R. R. L., Ahoopai, M., Geyer, M., Brandt, M., Zeiher, A. M., Vasa-Nicotera, M., Munzel, T., Wenzel, P., Gori, T. & Dimitriadis, Z. Sci Rep 12, 3073 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35197506
Renin, aldosterone, the aldosterone-to-renin ratio, and incident hypertension among normotensive subjects from the general population. Arnold, N., Hermanns, I. M., Schulz, A., Hahad, O., Schmitt, V. H., Panova-Noeva, M., Prochaska, J. H., Binder, H., Pfeiffer, N., Beutel, M., Lackner, K. J., Munzel, T. & Wild, P. S. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35199135
Role of TRPC6 in kidney damage after acute ischemic kidney injury. Zheng, Z., Tsvetkov, D., Bartolomaeus, T. U. P., Erdogan, C., Krugel, U., Schleifenbaum, J., Schaefer, M., Nurnberg, B., Chai, X., Ludwig, F. A., N'Diaye, G., Kohler, M. B., Wu, K., Gollasch, M. & Marko, L. Sci Rep 12, 3038 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35194063
Effects of Atrial Fibrillation on the Human Ventricle. Pabel, S., Knierim, M., Stehle, T., Alebrand, F., Paulus, M., Sieme, M., Herwig, M., Barsch, F., Kortl, T., Poppl, A., Wenner, B., Ljubojevic-Holzer, S., Molina, C. E., Dybkova, N., Camboni, D., Fischer, T. H., Sedej, S., Scherr, D., Schmid, C., Brochhausen, C. et al. Circ Res, CIRCRESAHA121319718 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35193397
Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging: From Basic Concepts to Emerging Methods. Holtackers, R. J., Emrich, T., Botnar, R. M., Kooi, M. E., Wildberger, J. E. & Kreitner, K. F. Rofo (2022). https://www.ncbi.nlm.nih.gov/pubmed/35196714
Surgery for infective endocarditis following low-intermediate risk transcatheter aortic valve replacement-a multicentre experience. Saha, S., Joskowiak, D., Marin-Cuartas, M., Diab, M., Schwaiger, B. M., Sandoval-Boburg, R., Popov, A. F., Weber, C., Varghese, S., Martens, A., Cebotari, S., Scherner, M., Eichinger, W., Holzhey, D., Dohle, D. S., Wahlers, T., Doenst, T., Misfeld, M., Mehilli, J., Massberg, S. et al. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35190828
Effect of Sunitinib Treatment on Skin Sodium Accumulation in Patients With Renal Cancer: a Pilot Study. Marko, L., Dorr, A., Linz, P., van den Meiracker, A. H., Garrelds, I. M., Kuehne, T., Dechend, R., Danser, A. H. J., Florcken, A. & Muller, D. N. Hypertension, HYPERTENSIONAHA12219079 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35189705
Preadmission antiplatelet therapy and treatment effect of ticagrelor versus prasugrel in patients with acute coronary syndromes - a subgroup analysis of the ISAR-REACT 5 trial. Lahu, S., Ndrepepa, G., Neumann, F. J., Menichelli, M., Bernlochner, I., Richardt, G., Wohrle, J., Witzenbichler, B., Hemetsberger, R., Mayer, K., Akin, I., Cassese, S., Gewalt, S., Xhepa, E., Kufner, S., Valina, C., Sager, H. B., Joner, M., Ibrahim, T., Laugwitz, K. L. et al. Eur Heart J Cardiovasc Pharmacother (2022). https://www.ncbi.nlm.nih.gov/pubmed/35191982
Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study. Kaura, A., Hartley, A., Panoulas, V., Glampson, B., Shah, A. S. V., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Thursz, M. R., Elliott, P., Hemmingway, H., Williams, B., Asselbergs, F. W., O'Sullivan, M., Lord, G. M., Trickey, A., Sterne, J. A., Haskard, D. O. et al. PLoS Med 19, e1003911 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35192610
Predictors of cardiopulmonary fitness in cancer-affected and -unaffected women with a pathogenic germline variant in the genes BRCA1/2 (LIBRE-1). Berling-Ernst, A., Yahiaoui-Doktor, M., Kiechle, M., Engel, C., Lammert, J., Grill, S., Dukatz, R., Rhiem, K., Baumann, F. T., Bischoff, S. C., Erickson, N., Schmidt, T., Niederberger, U., Siniatchkin, M. & Halle, M. Sci Rep 12, 2907 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35190584
QRS micro-fragmentation as a mortality predictor. Hnatkova, K., Andrsova, I., Novotny, T., Britton, A., Shipley, M., Vandenberk, B., Sprenkeler, D. J., Junttila, J., Reichlin, T., Schlogl, S., Vos, M. A., Friede, T., Bauer, A., Huikuri, H. V., Willems, R., Schmidt, G., Franz, M. R., Sticherling, C., Zabel, M. & Malik, M. Eur Heart J(2022). https://www.ncbi.nlm.nih.gov/pubmed/35187560
MRI-Detected Brain Lesions and Cognitive Function in Patients With Atrial Fibrillation Undergoing Left Atrial Catheter Ablation in the Randomized AXAFA-AFNET 5 Trial. Haeusler, K. G., Eichner, F. A., Heuschmann, P. U., Fiebach, J. B., Engelhorn, T., Blank, B., Callans, D., Elvan, A., Grimaldi, M., Hansen, J., Hindricks, G., Al-Khalidi, H. R., Mont, L., Nielsen, J. C., Piccini, J. P., Schotten, U., Themistoclakis, S., Vijgen, J., Di Biase, L. & Kirchhof, P. Circulation 145, 906-915 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35135308
Neurofilament proteins as a potential biomarker in chemotherapy-induced polyneuropathy. Huehnchen, P., Schinke, C., Bangemann, N., Dordevic, A. D., Kern, J., Maierhof, S. K., Hew, L., Nolte, L., Kortvelyessy, P., Gopfert, J. C., Ruprecht, K., Somps, C. J., Blohmer, J. U., Sehouli, J., Endres, M. & Boehmerle, W. JCI Insight 7 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35133982
Severe heart failure in the setting of inflammatory cardiomyopathy with likely pathogenic titin variant. Mueller, M., Zwinger, L., Klaassen, S., Poller, W., Monserrat Iglesias, L., Pablo Ochoa, J., Klingel, K., Landmesser, U. & Heidecker, B. Int J Cardiol Heart Vasc 39, 100969 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35198726
Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy. Huang, M., Yang, Z., Li, Y., Lan, H., Cyganek, L., Yuecel, G., Lang, S., Bieback, K., El-Battrawy, I., Zhou, X., Borggrefe, M. & Akin, I. Frontiers in Cardiovascular Medicine 8, 777463 (2022).
Bacteriophage therapy as a treatment option for complex cardiovascular implant infection: The German Heart Center Berlin experience. Tkhilaishvili, T., Potapov, E., Starck, C., Mulzer, J., Falk, V., Trampuz, A. & Schoenrath, F. The Journal of Heart and Lung Transplantation (2022).
Interventional Procedures for Left Ventricular Assist Device-Associated Complications. Lanmueller, P., Eulert-Grehn, J.-J., Unbehaun, A., Klein, C., Hommel, M., Kofler, M., Kempfert, J., Hoermandinger, C., Kaufmann, F., Stawowy, P., Dreysse, S., Mulzer, J., Mueller, M., Falk, V., Schoenrath, F., Potapov, E. & Just, I. A. ASAIO Journal Publish Ahead of Print (2022).
Coronary angiography in acute ischemic stroke patients: frequency and determinants of pathological findings in a multicenter cohort study. Litmeier, S., Meinel, T. R., von Rennenberg, R., Kniepert, J. U., Audebert, H. J., Endres, M., Jung, S., Scheitz, J. F. & Nolte, C. H. J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35182178
Conduction disturbances following transcatheter aortic valve implantation: Any room for improvement? Charitos, E. & Kim, W. K. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35182652
Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease. Talmor-Barkan, Y., Bar, N., Shaul, A. A., Shahaf, N., Godneva, A., Bussi, Y., Lotan-Pompan, M., Weinberger, A., Shechter, A., Chezar-Azerrad, C., Arow, Z., Hammer, Y., Chechi, K., Forslund, S. K., Fromentin, S., Dumas, M. E., Ehrlich, S. D., Pedersen, O., Kornowski, R. & Segal, E. Nat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35177859
Nationwide Registry-Based Analysis of Infective Endocarditis Risk After Pulmonary Valve Replacement. Stammnitz, C., Huscher, D., Bauer, U. M. M., Urban, A., Nordmeyer, J., Schubert, S., Photiadis, J., Berger, F., Klaassen, S. & German Competence Network for Congenital Heart Defects, I. J Am Heart Assoc, e022231 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35179045
Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis. Pappritz, K., Lin, J., El-Shafeey, M., Fechner, H., Kuhl, U., Alogna, A., Spillmann, F., Elsanhoury, A., Schulz, R., Tschope, C. & Van Linthout, S. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35178861
Microbiome and metabolome features of the cardiometabolic disease spectrum. Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. et al. Nat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35177860
Not only lungs: COVID-19 hits platelets as well. Bongiovanni, D., Klug, M., Valgimigli, M. & Bernlochner, I. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35178570
The Association of Depression and All-Cause Mortality: Explanatory Factors and the Influence of Gender. Wicke, F. S., Ernst, M., Otten, D., Werner, A., Dreier, M., Brahler, E., Tibubos, A. N., Reiner, I., Michal, M., Wiltink, J., Munzel, T., Lackner, K. J., Pfeiffer, N., Konig, J., Wild, P. S. & Beutel, M. E. J Affect Disord(2022). https://www.ncbi.nlm.nih.gov/pubmed/35176339
Rodent models for gait network disorders in Parkinson's disease - a translational perspective. Wenger, N., Vogt, A., Skrobot, M., Garulli, E. L., Kabaoglu, B., Salchow-Hommen, C., Schauer, T., Kroneberg, D., Schuhmann, M., Ip, C. W., Harms, C., Endres, M., Isaias, I., Tovote, P. & Blum, R. Exp Neurol, 114011 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176273
Evaluation of the spline reconstruction technique for preclinical PET imaging. Vrachliotis, A., Kastis, G. A., Protonotarios, N. E., Fokas, A. S., Nekolla, S. G., Anagnostopoulos, C. D., Costaridou, L. & Gaitanis, A. Comput Methods Programs Biomed 217, 106668 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176596
CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes. Stathopoulou, K., Schnittger, J., Raabe, J., Fleischer, F., Mangels, N., Piasecki, A., Findlay, J., Hartmann, K., Krasemann, S., Schlossarek, S., Uebeler, J., Wixler, V., Blake, D. J., Baillie, G. S., Carrier, L., Ehler, E. & Cuello, F. FEBS J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176204
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes. Li, L., Chen, Z., von Scheidt, M., Li, S., Steiner, A., Guldener, U., Koplev, S., Ma, A., Hao, K., Pan, C., Lusis, A. J., Pang, S., Kessler, T., Ermel, R., Sukhavasi, K., Ruusalepp, A., Gagneur, J., Erdmann, J., Kovacic, J. C., Bjorkegren, J. L. M. et al. Basic Res Cardiol 117, 6 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35175464
Deep breathing couples CSF and venous flow dynamics. Kollmeier, J. M., Gurbuz-Reiss, L., Sahoo, P., Badura, S., Ellebracht, B., Keck, M., Gartner, J., Ludwig, H. C., Frahm, J. & Dreha-Kulaczewski, S. Sci Rep 12, 2568 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35173200
Neutrophil-Platelet Interactions as Novel Treatment Targets in Cardiovascular Disease. Kaiser, R., Escaig, R., Erber, J. & Nicolai, L. Front Cardiovasc Med 8, 824112 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35174225
Prognostic Implications of a Second Peak of High-Sensitivity Troponin T After Myocardial Infarction. Hartikainen, T. S., Gossling, A., Sorensen, N. A., Lehmacher, J., Neumann, J. T., Blankenberg, S. & Westermann, D. Front Cardiovasc Med 8, 780198 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35174220
A novel Troponin I mutation associated with severe restrictive cardiomyopathy-a case report of a 27-year-old woman with fatigue. Gerhardt, T., Monserrat, L., Landmesser, U. & Poller, W. Eur Heart J Case Rep 6, ytac053 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35174310
Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development. Frenis, K., Kalinovic, S., Ernst, B. P., Kvandova, M., Al Zuabi, A., Kuntic, M., Oelze, M., Stamm, P., Bayo Jimenez, M. T., Kij, A., Keppeler, K., Klein, V., Strohm, L., Ubbens, H., Daub, S., Hahad, O., Kroller-Schon, S., Schmeisser, M. J., Chlopicki, S., Eckrich, J. et al. Front Mol Biosci 8, 814921 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35174211
Treatment standards for direct oral anticoagulants in patients with acute ischemic stroke and non-valvular atrial fibrillation: A survey among German stroke units. Fastner, C., Szabo, K., Samartzi, M., Kruska, M., Akin, I., Platten, M., Baumann, S. & Alonso, A. PLoS One 17, e0264122 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35176109
Muscarinic receptor activation reduces force and arrhythmias in human atria independent of IK,ACh. Petersen, J., Castro, L., Pedersen Bengaard, A. K., Pecha, S., Ismaili, D., Schulz, C., Sahni, J., Steenpass, A., Meier, C., Reichenspurner, H., Jespersen, T., Eschenhagen, T. & Christ, T. J Cardiovasc Pharmacol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170489
Distribution and prognostic impact of coronary artery disease and nonischemic cardiomyopathies in patients with electrical storm. Muller, J., Behnes, M., Ellguth, D., Schupp, T., Taton, G., Reiser, L., Engelke, N., Borggrefe, M., Reichelt, T., Bollow, A., Kim, S. H., Barth, C., Weidner, K., Battrawy, I. E., Ansari, U., Akin, M., Grosse Meininghaus, D., Mashayekhi, K. & Akin, I. Coron Artery Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170551
Patient profile and outcomes associated with follow-up in specialty vs. primary care in heart failure. Lindberg, F., Lund, L. H., Benson, L., Schrage, B., Edner, M., Dahlstrom, U., Linde, C., Rosano, G. & Savarese, G. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170237
Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I. Kamynina, A., Guttzeit, S., Eaton, P. & Cuello, F. Hypertension, HYPERTENSIONAHA12218756 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35168371
One-year results following PASCAL-based or MitraClip-based mitral valve transcatheter edge-to-edge repair. Geis, N. A., Schlegel, P., Heckmann, M. B., Katus, H. A., Frey, N., Crespo Lopez, P. & Raake, P. W. J. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35170230
The role of epigenetic clocks in explaining educational inequalities in mortality: a multi-cohort study and meta-analysis. Fiorito, G., Pedron, S., Ochoa-Rosales, C., McCrory, C., Polidoro, S., Zhang, Y., Dugue, P. A., Ratliff, S., Zhao, W. N., McKay, G. J., Costa, G., Solinas, M. G., Mullan Harris, K., Tumino, R., Grioni, S., Ricceri, F., Panico, S., Brenner, H., Schwettmann, L., Waldenberger, M. et al. J Gerontol A Biol Sci Med Sci (2022). https://www.ncbi.nlm.nih.gov/pubmed/35172329
Reply to Van den Eyde et al. Voges, I. & Gabbert, D. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35167668
Tackling postoperative sudden cardiac death in high-risk cardiac surgical patients-role of wearable cardioverter defibrillators. Starck, C., Kaemmel, J. & Falk, V. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35165712
Iron Deficiency and Reduced Muscle Strength in Patients with Acute and Chronic Ischemic Stroke. Scherbakov, N., Sandek, A., Valentova, M., Mayer, A., von Haehling, S., Jankowska, E., Anker, S. D. & Doehner, W. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35160047
Population-based screening in children for early diagnosis and treatment of familial hypercholesterolemia: design of the VRONI study. Sanin, V., Schmieder, R., Ates, S., Schlieben, L. D., Wiehler, J., Sun, R., Decker, M., Sander, M., Holdenrieder, S., Kohlmayer, F., Friedmann, A., Mall, V., Feiler, T., Dressler, A., Strom, T. M., Prokisch, H., Meitinger, T., von Scheidt, M., Koenig, W., Leipold, G. et al. Eur J Public Health (2022). https://www.ncbi.nlm.nih.gov/pubmed/35165720
Association between Duration of Deep Hypothermic Circulatory Arrest and Surgical Outcome in Patients with Acute Type A Aortic Dissection: A Large Retrospective Cohort Study. Salehi Ravesh, M., Friedrich, C., Schoettler, J., Hummitzsch, L., Elke, G., Salem, M., Lutter, G., Puehler, T., Cremer, J. & Haneya, A. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35160094
Longitudinal association of Apolipoprotein E polymorphism with lipid profile, type 2 diabetes and metabolic syndrome: Results from a 15 year follow-up study. Pitchika, A., Ricardo Paulista Markus, M., Schipf, S., Teumer, A., Van der Auwera, S., Nauck, M., Dorr, M., Felix, S., Jorgen Grabe, H., Volzke, H. & Ittermann, T. Diabetes Res Clin Pract 185, 109778 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35167921
Switching in the expression pattern of actin isoforms marks the onset of contractility and distinct mechanodynamic behavior during cardiomyocyte differentiation. Pires, R. H., Dau, T. H., Manu, E., Shree, N. & Otto, O. Physiol Rep 10, e15171 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35166060
Soluble ST2 Receptor: Biomarker of Left Ventricular Impairment and Functional Status in Patients with Inflammatory Cardiomyopathy. Obradovic, D. M., Buttner, P., Rommel, K. P., Blazek, S., Loncar, G., von Haehling, S., von Roeder, M., Lucke, C., Gutberlet, M., Thiele, H., Lurz, P. & Besler, C. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35159224
The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure. Kubin, T., Gajawada, P., Bramlage, P., Hein, S., Berge, B., Cetinkaya, A., Burger, H., Schonburg, M., Schaper, W., Choi, Y. H. & Richter, M. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35163735
Improving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data. Gheorghita, B. A., Itu, L. M., Sharma, P., Suciu, C., Wetzl, J., Geppert, C., Ali, M. A. A., Lee, A. M., Piechnik, S. K., Neubauer, S., Petersen, S. E., Schulz-Menger, J. & Chitiboi, T. Sci Rep 12, 2391 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35165324
Iron deficiency is related to low functional outcome in patients at early rehabilitation after acute stroke. Doehner, W., Scherbakov, N., Schellenberg, T., Jankowska, E. A., Scheitz, J. F., von Haehling, S. & Joebges, M. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35166066
Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants. Speck, D., Kleinau, G., Meininghaus, M., Erbe, A., Einfeldt, A., Szczepek, M., Scheerer, P. & Putter, V. Front Pharmacol 12, 826112 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35153771
Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19. Sala, L., Leonov, V., Mura, M., Giannetti, F., Khudiakov, A., Moretti, A., Crotti, L., Gnecchi, M. & Schwartz, P. J. Front Physiol 12, 730127 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35153806
Paracrine Interleukin 6 Induces Cerebral Remodeling at Early Stages After Unilateral Common Carotid Artery Occlusion in Mice. Kuffner, M. T. C., Koch, S. P., Kirchner, M., Mueller, S., Lips, J., An, J., Mertins, P., Dirnagl, U., Endres, M., Boehm-Sturm, P., Harms, C. & Hoffmann, C. J. Front Cardiovasc Med 8, 805095 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35155612
Stroke events after transcatheter aortic valve implantation: Temporal relationships and affected brain regions. Linder, M., Higgen, F. L., Voigtlander, L., Weimann, J., Ludwig, S., Waldschmidt, L., Focke, C., Bhadra, O., Grundmann, D., Demal, T., von Zastrow, A., Schafer, A., Schirmer, J., Reichenspurner, H., Blankenberg, S., Westermann, D., Schofer, N., Conradi, L., Thomalla, G. & Seiffert, M. Am Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35149038
The European Registry for Patients with Mechanical Circulatory Support of the European Association for Cardio-Thoracic Surgery: third report. de By, T., Schoenrath, F., Veen, K. M., Mohacsi, P., Stein, J., Alkhamees, K. M. M., Anastasiadis, K., Berhnardt, A., Beyersdorf, F., Caliskan, K., Reineke, D., Damman, K., Fiane, A., Gkouziouta, A., Gollmann-Tepekoylu, C., Finn, G., Hulman, M., Iacovoni, A., Loforte, A., Merkely, B. et al. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35150247
Impact of prenatal and childhood adversity effects around World War II on multimorbidity: results from the KORA-Age study. Arshadipour, A., Thorand, B., Linkohr, B., Rospleszcz, S., Ladwig, K. H., Heier, M. & Peters, A. BMC Geriatr 22, 115 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35148691
Target and non-target vessel related events at 10 years post percutaneous coronary intervention. Coughlan, J. J., Aytekin, A., Xhepa, E., Cassese, S., Joner, M., Koch, T., Wiebe, J., Lenz, T., Rheude, T., Pellegrini, C., Gewalt, S., Ibrahim, T., Laugwitz, K. L., Schunkert, H., Kastrati, A. & Kufner, S. Clin Res Cardiol(2022). https://www.ncbi.nlm.nih.gov/pubmed/35147767
Ticagrelor after Acute Coronary Syndrome: One For All or Part of Personalized Medicine? Akin, I. & Nienaber, C. A. Lancet Reg Health Eur 14, 100309 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35146475
Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies. Rodriguez-Polo, I. & Behr, R. Neural Regen Res 17, 1867-1874 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35142660
Serum Calcification Propensity and Calcification of the Abdominal Aorta in Patients With Primary Aldosteronism. Kantauskaite, M., Bolten, K., Boschheidgen, M., Schmidt, C., Kolb, T., Eckardt, K. U., Pasch, A., Schimmoller, L., Rump, L. C., Voelkl, J. & Stegbauer, J. Front Cardiovasc Med 9, 771096 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35141300
Functional improvement following direct interventional leaflet repair of severe tricuspid regurgitation. Volz, M. J., Hoerbrand, I., Konstandin, M. H., Mereles, D., Weiss, C., Warnecke, G., Frey, N., Aurich, M. & Raake, P. W. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137567
The additional use of strain measurements for timing of treatment in severe aortic regurgitation. Sinning, C. Int J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35138473
Feasibility and preliminary efficacy of perioperative interventions in patients undergoing coronary artery bypass grafting: the randomized controlled I-COPE trial. Sadlonova, M., Nagel, J., Becker, S., Neumann, S., Staab, J., Meyer, T., Celano, C. M., Amonoo, H. L., Fangauf, S. V., Herrmann-Lingen, C., Kutschka, I. & Friedrich, M. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137022
Thyroid Function and the Risk of Prediabetes and Type 2 Diabetes. Roa Duenas, O. H., Van der Burgh, A. C., Ittermann, T., Ligthart, S., Ikram, M. A., Peeters, R. & Chaker, L. J Clin Endocrinol Metab (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137143
Atrial fibrillation in patients on left ventricular assist device support-to treat or not to treat. Potapov, E. V. & Schoenrath, F. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35137027
Targeted proteomics improves cardiovascular risk prediction in secondary prevention. Nurmohamed, N. S., Belo Pereira, J. P., Hoogeveen, R. M., Kroon, J., Kraaijenhof, J. M., Waissi, F., Timmerman, N., Bom, M. J., Hoefer, I. E., Knaapen, P., Catapano, A. L., Koenig, W., de Kleijn, D., Visseren, F. L. J., Levin, E., Stroes, E. S. G. & Group, U.-S. S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35139537
Prognostic impact of secondary prevention after coronary artery bypass grafting-insights from the TiCAB trial. Heer, T., von Scheidt, M., Boening, A., Heyken, C., Gusmini, F., de Waha, A., Kuna, C., Fach, A., Grothusen, C., Oberhoffer, M., Knosalla, C., Walther, T., Danner, B. C., Misfeld, M., Wimmer-Greinecker, G., Siepe, M., Grubitzsch, H., Joost, A., Schaefer, A., Conradi, L. et al. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35138350
MRI-Detected Brain Lesions and Cognitive Function in Atrial Fibrillation Patients Undergoing Left Atrial Catheter Ablation in the Randomized AXAFA-AFNET 5 Trial. Hausler, K. G., Eichner, F. A., Heuschmann, P. U., Fiebach, J. B., Engelhorn, T., Blank, B., Callans, D., Elvan, A., Grimaldi, M., Hansen, J., Hindricks, G., Al-Khalidi, H. R., Mont, L., Nielsen, J. C., Piccini, J. P., Schotten, U., Themistoclakis, S., Vijgen, J., Di Biase, L. & Kirchhof, P. Circulation (2022). https://www.ncbi.nlm.nih.gov/pubmed/35135308
Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques. Edsfeldt, A., Swart, M., Singh, P., Dib, L., Sun, J., Cole, J. E., Park, I., Al-Sharify, D., Persson, A., Nitulescu, M., Das Neves Borges, P., Kassiteridi, C., Goddard, M. E., Lee, R., Volkov, P., Orho-Melander, M., Maegdefessel, L., Nilsson, J., Udalova, I., Goncalves, I. et al. Eur Heart J(2022). https://www.ncbi.nlm.nih.gov/pubmed/35139193
J wave syndromes in patients with spinal and bulbar muscular atrophy. Steinmetz, K., Rudic, B., Borggrefe, M., Muller, K., Siebert, R., Rottbauer, W., Ludolph, A., Buckert, D. & Rosenbohm, A. J Neurol(2022). https://www.ncbi.nlm.nih.gov/pubmed/35132468
Birth weight and heart failure: hindsight as an exact science? Fonseca, G., Garfias-Veitl, T. & von Haehling, S. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35134156
Myogenic Vasoconstriction Requires Canonical Gq/11 Signaling of the Angiotensin II Type 1 Receptor. Cui, Y., Kassmann, M., Nickel, S., Zhang, C., Alenina, N., Anistan, Y. M., Schleifenbaum, J., Bader, M., Welsh, D. G., Huang, Y. & Gollasch, M. J Am Heart Assoc 11, e022070 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35132870
Teleproctoring for Training in Structural Heart Interventions: Initial Real-World Experience During the COVID-19 Pandemic. Beyhoff, N., Zhu, M., Zanders, L., Leistner, D. M., Nobles, A., Schroeder, M., Barbieri, F., Landmesser, U. & Reinthaler, M. J Am Heart Assoc 11, e023757 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35132869
[Drop in oxygen saturation and blood pressure as well as increase in central venous pressure during mitral valve clipping in an 81-year-old female patient]. Volz, M. J., Aurich, M., Konstandin, M., Katus, H. A., Frey, N., Kreusser, M. M. & Raake, P. W. Internist (Berl) (2022). https://www.ncbi.nlm.nih.gov/pubmed/35129621
Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement. Sun, X., Hao, Y., Sebastian Kiekenap, J. F., Emeis, J., Steitz, M., Breitenstein-Attach, A., Berger, F. & Schmitt, B. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35129181
Recommendations in pre-procedural imaging assessment for TAVI intervention: SIC-SIRM position paper part 2 (CT and MR angiography, standard medical reporting, future perspectives). Marano, R., Pontone, G., Agricola, E., Alushi, B., Bartorelli, A., Cameli, M., Carrabba, N., Esposito, A., Faletti, R., Francone, M., Galea, N., Golino, P., Guglielmo, M., Palmisano, A., Petronio, S., Petulla, M., Pradella, S., Ribichini, F., Romeo, F., Russo, V. et al. Radiol Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35129758
Different Rates of Bioprosthetic Aortic Valve Failure With Perimount and Trifecta Bioprostheses. Lange, R., Alalawi, Z., Voss, S., Boehm, J., Krane, M. & Vitanova, K. Front Cardiovasc Med 8, 822893 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35127875
Phosphodiesterases S-sulfhydration contributes to human skeletal muscle function. Vellecco, V., Panza, E., Bibli, S. I., Casillo, G. M., Raucci, F., Manzo, O. L., Smimmo, M., Villani, R., Cavezza, M. R., Fleming, I., d'Emmanuele di Villa Bianca, R., Maione, F., Cirino, G. & Bucci, M. Pharmacol Res 177, 106108 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35121122
Stable patients with suspected myocardial ischemia: comparison of machine-learning computed tomography-based fractional flow reserve and stress perfusion cardiovascular magnetic resonance imaging to detect myocardial ischemia. Lossnitzer, D., Klenantz, S., Andre, F., Goerich, J., Schoepf, U. J., Pazzo, K. L., Sommer, A., Brado, M., Guckel, F., Sokiranski, R., Becher, T., Akin, I., Buss, S. J. & Baumann, S. BMC Cardiovasc Disord 22, 34 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35120459
Generation of a CRISPR/Cas edited human induced pluripotent stem cell line DHMi005-A-1 carrying a patient-specific disease-causing point mutation in the TBX5 gene. Lahm, H., Heinrich, P., Zierler, E., Dzilic, E., Neb, I., Luzius, T., Doppler, S. A., Schneider, S., Lange, R., Krane, M. & Dressen, M. Stem Cell Res 60, 102691 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35121196
Case Report: Cytomegalovirus Reactivation and Pericarditis Following ChAdOx1 nCoV-19 Vaccination Against SARS-CoV-2. Pluss, M., Mese, K., Kowallick, J. T., Schuster, A., Tampe, D. & Tampe, B. Front Immunol 12, 784145 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35116025
Effects of sacubitril/valsartan versus valsartan on renal function in patients with and without diabetes and heart failure with preserved ejection fraction: insights from PARAGON-HF. Peikert, A., Vaduganathan, M., Mc Causland, F., Claggett, B. L., Chatur, S., Packer, M., Pfeffer, M. A., Zannad, F., Lefkowitz, M. P., Pieske, B., Dungen, H. D., McMurray, J. J. V. & Solomon, S. D. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35119183
Early risk stratification in patients with cardiogenic shock irrespective of the underlying cause - the Cardiogenic Shock Score. Beer, B. N., Jentzer, J. C., Weimann, J., Dabboura, S., Yan, I., Sundermeyer, J., Kirchhof, P., Blankenberg, S., Schrage, B. & Westermann, D. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35119176
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels. S, O. B., Holmes, A. P., Johnson, D. M., Kabir, S. N., C, O. S., M, O. R., Avezzu, A., Reyat, J. S., Hall, A. W., Apicella, C., Ellinor, P. T., Niederer, S., Tucker, N. R., Fabritz, L., Kirchhof, P. & Pavlovic, D. J Mol Cell Cardiol 166, 23-35 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35114252
Impact of thyroid dysfunction on short-term outcomes and long-term mortality in patients with pulmonary embolism. Pohl, K. R., Hobohm, L., Krieg, V. J., Sentler, C., Rogge, N. I. J., Steimke, L., Ebner, M., Lerchbaumer, M., Hasenfuss, G., Konstantinides, S., Lankeit, M. & Keller, K. Thromb Res 211, 70-78 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35114459
Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor. Daugherty, A., Hegele, R. A., Lu, H. S., Mackman, N., Rader, D. J. & Weber, C. Arterioscler Thromb Vasc Biol, ATVBAHA122317426 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35109675
Interactions Between Atrial Fibrillation and Natriuretic Peptide in Predicting Heart Failure Hospitalization or Cardiovascular Death. Brady, P. F., Chua, W., Nehaj, F., Connolly, D. L., Khashaba, A., Purmah, Y. J. V., Ul-Qamar, M. J., Thomas, M. R., Varma, C., Schnabel, R. B., Zeller, T., Fabritz, L. & Kirchhof, P. F. J Am Heart Assoc 11, e022833 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35112889
Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators. Wesseler, F., Riege, D., Puthanveedu, M., Halver, J., Muller, E., Bertrand, J., Antonchick, A. P., Sievers, S., Waldmann, H. & Schade, D. J Med Chem (2022). https://www.ncbi.nlm.nih.gov/pubmed/35108017
Diffusion-Weighted Imaging and Fluid-Attenuated Inversion Recovery Quantification to Predict Diffusion-Weighted Imaging-Fluid-Attenuated Inversion Recovery Mismatch Status in Ischemic Stroke With Unknown Onset. Scheldeman, L., Wouters, A., Dupont, P., Christensen, S., Boutitie, F., Cheng, B., Ebinger, M., Endres, M., Fiebach, J. B., Gerloff, C., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Thijs, V., Thomalla, G. & Lemmens, R. Stroke, STROKEAHA121036871 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35105179
A quantitative RT-PCR protocol to adapt and quantify RBM20-dependent exon splicing of targets at the human locus. Rebs, S., Buchwald, T. A. & Streckfuss-Bomeke, K. STAR Protoc 3, 101117 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35106501
Successfully implemented artificial intelligence and machine learning applications in cardiology: State-of-the-art review. Van den Eynde, J., Lachmann, M., Laugwitz, K. L., Manlhiot, C. & Kutty, S. Trends Cardiovasc Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35101642
Prediction of risk for bleeding, myocardial infarction and mortality after percutaneous coronary intervention in patients with acute coronary syndromes. Ndrepepa, G., Neumann, F. J., Menichelli, M., Richardt, G., Cassese, S., Xhepa, E., Kufner, S., Lahu, S., Aytekin, A., Sager, H. B., Joner, M., Ibrahim, T., Muller, A., Fusaro, M., Hapfelmeier, A., Laugwitz, K. L., Schunkert, H., Kastrati, A. & Kasel, M. Coron Artery Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35102066
Mental Health-Related Risk Factors and Interventions in Patients with Heart Failure. A Position Paper endorsed by the European Association of Preventive Cardiology (EAPC). Ladwig, K. H., Baghai, T. C., Doyle, F., Hamer, M., Herrmann-Lingen, C., Kunschitz, E., Lemogne, C., Beresnevaite, M., Compare, A., von Kanel, R., Sager, H. B. & Kop, W. J. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35104845
Improved Quantification of Cell Density in the Arterial Wall-A Novel Nucleus Splitting Approach Applied to 3D Two-Photon Laser-Scanning Microscopy. van der Laan, K. W. F., Reesink, K. D., van der Bruggen, M. M., Jaminon, A. M. G., Schurgers, L. J., Megens, R. T. A., Huberts, W., Delhaas, T. & Spronck, B. Front Physiol 12, 814434 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35095571
Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine. Schoger, E., Lelek, S., Panakova, D. & Zelarayan, L. C. Front Cardiovasc Med 8, 783072 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35097003
Atrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration. Rivard, L., Friberg, L., Conen, D., Healey, J. S., Berge, T., Boriani, G., Brandes, A., Calkins, H., Camm, A. J., Yee Chen, L., Lluis Clua Espuny, J., Collins, R., Connolly, S., Dagres, N., Elkind, M. S. V., Engdahl, J., Field, T. S., Gersh, B. J., Glotzer, T. V., Hankey, G. J. et al. Circulation 145, 392-409 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35100023
Coronary Artery Disease in Patients Presenting With Acute Ischemic Stroke or Transient Ischemic Attack and Elevated Troponin Levels. Kruska, M., Kolb, A., Fastner, C., Mildenberger, I., Hetjens, S., Kittel, M., Bail, K., Behnes, M., Akin, I., Borggrefe, M., Szabo, K. & Baumann, S. Front Neurol 12, 781553 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35095727
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures. Gonenc, II, Wolff, A., Schmidt, J., Zibat, A., Muller, C., Cyganek, L., Argyriou, L., Raschle, M., Yigit, G. & Wollnik, B. Hum Mol Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35099000
Muscle Mass and Inflammation in Older Adults: Impact of the Metabolic Syndrome. Buchmann, N., Fielitz, J., Spira, D., Konig, M., Norman, K., Pawelec, G., Goldeck, D., Demuth, I. & Steinhagen-Thiessen, E. Gerontology, 1-10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35100595
März
Paper of the Month
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection.
DZHK authors: Kami Pekayvaz, Alexander Leunig, Rainer Kaiser, Clemens Scherer, Kathrin Saar, Lukas Tomas, Christian Schulz, Norbert Hubner, Steffen Massberg, Konstantin Stark, Leo Nicolai, Nat Commun (2022).
Pulmonary Embolism and Pregnancy-Challenges in Diagnostic and Therapeutic Decisions in High-Risk Patients. Hobohm, L., Farmakis, I. T., Munzel, T., Konstantinides, S. & Keller, K. Front Cardiovasc Med9, 856594 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35350540
Novel Nongenetic Murine Model of Hyperglycemia and Hyperlipidemia-Associated Aggravated Atherosclerosis. Gaul, S., Shahzad, K., Medert, R., Gadi, I., Mader, C., Schumacher, D., Wirth, A., Ambreen, S., Fatima, S., Boeckel, J. N., Khawaja, H., Haas, J., Brune, M., Nawroth, P. P., Isermann, B., Laufs, U. & Freichel, M. Front Cardiovasc Med 9, 813215 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35350534
Pak2 Regulation of Nrf2 Serves as a Novel Signaling Nexus Linking ER Stress Response and Oxidative Stress in the Heart. Binder, P., Nguyen, B., Collins, L., Zi, M., Liu, W., Christou, F., Luo, X., Hille, S. S., Frey, N., Cartwright, E. J., Chernoff, J., Muller, O. J., Guan, K. & Wang, X. Front Cardiovasc Med 9, 851419 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35350536
Molecular consequences of SARS-CoV-2 liver tropism. Wanner, N., Andrieux, G., Badia, I. M. P., Edler, C., Pfefferle, S., Lindenmeyer, M. T., Schmidt-Lauber, C., Czogalla, J., Wong, M. N., Okabayashi, Y., Braun, F., Lutgehetmann, M., Meister, E., Lu, S., Noriega, M. L. M., Gunther, T., Grundhoff, A., Fischer, N., Brauninger, H., Lindner, D. et al. Nat Metab 4, 310-319 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35347318
Severe Acute Respiratory Distress Syndrome (ARDS) or Severely Increased Chest Wall Elastance?Lindner, S., Durschmied, D., Akin, I. & Britsch, S. Cureus 14, e22541 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35345704
Requirement of Na+/H+ Exchanger NHE1 for Vasopressin-Induced Osteogenic Signaling and Calcification in Human Aortic Smooth Muscle Cells. Zhu, X., Ma, K., Zhou, K., Pan, X., Liu, J., Nurnberg, B., Alesutan, I., Volkl, J. & Lang, F. Kidney Blood Press Res 47, 399-409 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35339998
Immuno-PET Imaging of Atherosclerotic Plaques with [(89)Zr]Zr-Anti-CD40 mAb-Proof of Concept. Poels, K., Schreurs, M., Jansen, M., Vugts, D. J., Seijkens, T. T. P., van Dongen, G., Lutgens, E. & Beaino, W. Biology (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35336782
Boosting targeted genome editing using the hei-tag. Thumberger, T., Tavhelidse-Suck, T., Gutierrez-Triana, J. A., Cornean, A., Medert, R., Welz, B., Freichel, M. & Wittbrodt, J. Elife 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35333175
Decreased Intrathecal Concentrations of Free Light Chains Kappa in Multiple Sclerosis Patients Taking Very High Effective Disease-Modifying Treatment. Susse, M., Konen, F. F., Schwenkenbecher, P., Budde, K., Nauck, M., Grothe, M., Hannich, M. J. & Skripuletz, T. Diagnostics (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35328273
Mechanistic Insights into Inorganic Nitrite-Mediated Vasodilation of Isolated Aortic Rings under Oxidative/Hypertensive Conditions and S-Nitros(yl)ation of Proteins in Germ-Free Mice. Stamm, P., Kalinovic, S., Oelze, M., Steven, S., Czarnowski, A., Kvandova, M., Bayer, F., Reinhardt, C., Munzel, T. & Daiber, A. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35327532
Repair of Mitral Valves with Severe Annular Dilatation and Abundant Leaflet Tissue Using a Prosthetic Ring with a Large Anterior-Posterior Diameter. Sideris, K., Burri, M., Bordne, J., Vitanova, K., Voss, B., Krane, M. & Lange, R. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35330034
Association of Plasma Methylglyoxal Increase after Myocardial Infarction and the Left Ventricular Ejection Fraction. Heber, S., Haller, P. M., Kiss, A., Jager, B., Huber, K. & Fischer, M. J. M. Biomedicines 10(2022). https://www.ncbi.nlm.nih.gov/pubmed/35327407
Transcatheter Aortic Valve Replacement with the Self-Expandable Core Valve Evolut Prosthesis Using the Cusp-Overlap vs. Tricusp-View. Doldi, P. M., Stolz, L., Escher, F., Steffen, J., Gmeiner, J., Roden, D., Linnemann, M., Low, K., Deseive, S., Stocker, T. J., Orban, M., Theiss, H., Rizas, K., Curta, A., Sadoni, S., Buech, J., Joskowiak, D., Peterss, S., Hagl, C., Massberg, S. et al. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35329887
Lipoprotein(a) and Metabolic Syndrome. Buchmann, N., Ittermann, T., Demuth, I., Markus, M. R. P., Volzke, H., Dorr, M., Friedrich, N., Lerch, M. M., Santos, R. D., Schipf, S. & Steinhagen-Thiessen, E. Dtsch Arztebl Int 119, 270-276 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35331368
Soluble ST2 as a Potential Biomarker for Risk Assessment of Pulmonary Hypertension in Patients Undergoing TAVR? Boxhammer, E., Mirna, M., Baz, L., Bacher, N., Topf, A., Sipos, B., Franz, M., Kretzschmar, D., Hoppe, U. C., Lauten, A. & Lichtenauer, M. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35330140
Effects of Artificial Intelligence-Derived Body Composition on Kidney Graft and Patient Survival in the Eurotransplant Senior Program. Beetz, N. L., Geisel, D., Shnayien, S., Auer, T. A., Globke, B., Ollinger, R., Trippel, T. D., Schachtner, T. & Fehrenbach, U. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35327356
Cardiovascular Inflammaging: Mechanisms and Translational Aspects. Barcena, M. L., Aslam, M., Pozdniakova, S., Norman, K. & Ladilov, Y. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35326461
Somatostatin Primes Endothelial Cells for Agonist-Induced Hyperpermeability and Angiogenesis In Vitro. Aslam, M., Idrees, H., Ferdinandy, P., Helyes, Z., Hamm, C. & Schulz, R. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35328517
Glucose Counteracts Isoprenaline Effects on Ion Channel Functions in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Qiao, L., Fan, X., Yang, Z., El-Battrawy, I., Zhou, X. & Akin, I. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35323624
Pleiotropic Effects of PCSK9: Focus on Thrombosis and Haemostasis. Puccini, M., Landmesser, U. & Rauch, U. Metabolites 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35323669
A Case Series of Concomitant Cardiac Electrical Disease among Takotsubo Syndrome Patients and Literature Review. El-Battrawy, I., Erath, J. W., Vamos, M., Aweimer, A., Mugge, A., Lang, S., Ansari, U., Gietzen, T. & Akin, I. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35323627
Disruptors of AKAP-Dependent Protein-Protein Interactions. Walker-Gray, R., Pallien, T., Miller, D. C., Oder, A., Neuenschwander, M., von Kries, J. P., Diecke, S. & Klussmann, E. Methods Mol Biol 2483, 117-139 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35286673
Generation of Transgenic Mice Expressing Cytosolic and Targeted FRET Biosensors for cAMP and cGMP. Kurelic, R. & Nikolaev, V. O. Methods Mol Biol 2483, 241-254 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35286680
Live Cell Imaging of Cyclic Nucleotides in Human Cardiomyocytes. Beneke, K. & Molina, C. E. Methods Mol Biol 2483, 195-204 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35286677
The Ketogenic Diet: Is It an Answer for Sarcopenic Obesity? Ilyas, Z., Perna, S., T, A. A., Zahid, M. N., Spadaccini, D., Gasparri, C., Peroni, G., Faragli, A., Alogna, A., La Porta, E., Ali Redha, A., Negro, M., Cerullo, G., D'Antona, G. & Rondanelli, M. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35276979
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing. Kogan, P. S., Wirth, F., Tomar, A., Darr, J., Teperino, R., Lahm, H., Dressen, M., Puluca, N., Zhang, Z., Neb, I., Beck, N., Luzius, T., de la Osa de la Rosa, L., Gartner, K., Huls, C., Zeidler, R., Ramanujam, D., Engelhardt, S., Wenk, C., Holdt, L. M. et al. Basic Res Cardiol 117, 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35258704
Relevance of Cor Pulmonale in COPD With and Without Pulmonary Hypertension: A Retrospective Cohort Study. Yogeswaran, A., Kuhnert, S., Gall, H., Faber, M., Krauss, E., Rako, Z. A., Keranov, S., Grimminger, F., Ghofrani, H. A., Naeije, R., Seeger, W., Richter, M. J. & Tello, K. Front Cardiovasc Med 9, 826369 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35252399
Dysregulated Immunity in Pulmonary Hypertension: From Companion to Composer. Funk-Hilsdorf, T. C., Behrens, F., Grune, J. & Simmons, S. Front Physiol 13, 819145 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35250621
Midwall Fibrosis and Cardiac Mechanics: Rigid Body Rotation Is a Novel Marker of Disease Severity in Pediatric Primary Dilated Cardiomyopathy. Al-Wakeel-Marquard, N., Seidel, F., Kuhnisch, J., Kuehne, T., Berger, F., Messroghli, D. R. & Klaassen, S. Front Cardiovasc Med 8, 810005 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35252369
Minimally invasive approach to the treatment of atrial fibrillation: Concomitant Convergent and LARIAT procedure. Van Praet, K. M., Nersesian, G., Kofler, M., Heil, E., Unbehaun, A., Klein, C., Kempfert, J., Falk, V., Gerds-Li, J. H. & Starck, C. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35245005
COVID-19 and the Vasculature: Current Aspects and Long-Term Consequences. Martinez-Salazar, B., Holwerda, M., Studle, C., Piragyte, I., Mercader, N., Engelhardt, B., Rieben, R. & Doring, Y. Front Cell Dev Biol10, 824851 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35242762
Editorial: Metabolic Regulation of Cardiac and Vascular Cell Function: Physiological and Pathophysiological Implications. Khan, M., Volkers, M. & Wende, A. R. Front Physiol 13, 849869 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35242056
Laser Capture Microdissection-Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research. Zhang, X., Wang, Z., Zhang, C., Li, Y., Lu, S., Steffens, S., Mohanta, S., Weber, C., Habenicht, A. & Yin, C. Methods Mol Biol 2419, 715-726 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35237997
Combined Single-Cell RNA and Single-Cell alpha/beta T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis. Wang, Z., Zhang, X., Zhang, C., Li, Y., Lu, S., Mohanta, S., Weber, C., Habenicht, A. & Yin, C. Methods Mol Biol 2419, 727-746 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35237998
Tissue Clearing Approaches in Atherosclerosis. Sun, T., Li, Y., Forstera, B., Stanic, K., Lu, S., Steffens, S., Yin, C., Erturk, A., Megens, R. T. A., Weber, C., Habenicht, A. & Mohanta, S. K. Methods Mol Biol 2419, 747-763 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35237999
Three-Dimensional Visualization of Atherosclerotic Vessels by Tissue Clearing and Light-Sheet Fluorescence Microscopy. Becher, T., Riascos-Bernal, D. F., Chi, J., Cohen, P. & Sibinga, N. E. S. Methods Mol Biol 2419, 841-851 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35238005
Circulating microRNAs in the prediction of BAV aortopathy: do the expression patterns correlate between blood and aortic tissue? Naito, S., Sequeira-Gross, T., Petersen, J., Detlef, I., Sachse, M., Zeller, T., Reichenspurner, H. & Girdauskas, E. Rev Cardiovasc Med 23, 47 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35229538
Relationship between plasma Neuregulin-1 and cardiac function in patients with ST-elevation myocardial infarction. Haller, P. M., Goncalves, I. F., Acar, E., Jager, B., Pilz, P. M., Wojta, J., Huber, K., Kiss, A. & Podesser, B. K. Rev Cardiovasc Med 23, 63 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35229554
Iron Deficiency Impacts Diastolic Function, Aerobic Exercise Capacity, and Patient Phenotyping in Heart Failure With Preserved Ejection Fraction: A Subanalysis of the OptimEx-Clin Study. Gevaert, A. B., Mueller, S., Winzer, E. B., Duvinage, A., Van de Heyning, C. M., Pieske-Kraigher, E., Beckers, P. J., Edelmann, F., Wisloff, U., Pieske, B., Adams, V., Halle, M., Van Craenenbroeck, E. M. & OptimEx-Clin Study, G. Front Physiol 12, 757268 (2021). https://www.ncbi.nlm.nih.gov/pubmed/35222057
Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: A Position Paper from the ESC Working Group on Thrombosis, in collaboration with the European Heart Rhythm Association, the Association for Acute CardioVascular Care and the Asia-Pacific Heart Rhythm Society. Gorog, D. A., Gue, Y. X., Chao, T. F., Fauchier, L., Ferreiro, J. L., Huber, K., Konstantinidis, S. V., Lane, D. A., Marin, F., Oldgren, J., Potpara, T., Roldan, V., Rubboli, A., Sibbing, D., Tse, H. F., Vilahur, G. & Lip, G. Y. H. Europace 24, 1844-1871 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35323922
The epigenetic enzyme DOT1L orchestrates vascular smooth muscle cell-monocyte crosstalk and protects against atherosclerosis via the NF-kappaB pathway. Farina, F. M., Serio, S., Hall, I. F., Zani, S., Cassanmagnago, G. A., Climent, M., Civilini, E., Condorelli, G., Quintavalle, M. & Elia, L. Eur Heart J 43, 4562-4576 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35292818
Heart-Type Fatty Acid Binding Protein, Cardiovascular Outcomes, and Death: Findings From the German CKD Cohort Study. Schneider, M. P., Schmid, M., Nadal, J., Wanner, C., Krane, V., Floege, J., Saritas, T., Busch, M., Sitter, T., Friedrich, N., Stockmann, H., Meiselbach, H., Nauck, M., Kronenberg, F. & Eckardt, K. U. Am J Kidney Dis 80, 483-494.e481 (2022).
Animal models of pulmonary hypertension due to left heart disease. Liu, S. F. & Yan, Y. Animal Model Exp Med 5, 197-206 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35234367
Multicenter comparison of latest-generation balloon-expandable versus self-expanding transcatheter heart valves: Ultra versus Evolut. Rheude, T., Pellegrini, C., Allali, A., Bleiziffer, S., Kim, W. K., Neuser, J., Landt, M., Rudolph, T., Renker, M., Widder, J. D., Qu, L., Alvarez-Covarrubias, H. A., Mayr, N. P., Richardt, G., Xhepa, E. & Joner, M. Int J Cardiol 357, 115-120 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35337936
Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects. Dyck, J. R. B., Sossalla, S., Hamdani, N., Coronel, R., Weber, N. C., Light, P. E. & Zuurbier, C. J. J Mol Cell Cardiol 167, 17-31 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35331696
P2Y12-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction. Seung, H., Wrobel, J., Wadle, C., Buhler, T., Chiang, D., Rettkowski, J., Cabezas-Wallscheid, N., Hechler, B., Stachon, P., Maier, A., Weber, C., Wolf, D., Duerschmied, D., Idzko, M., Bode, C., von Zur Muhlen, C., Hilgendorf, I. & Heidt, T. Basic Res Cardiol 117, 16 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35353230
Comparison of cardiac volumetry using real-time MRI during free-breathing with standard cine MRI during breath-hold in children. Rower, L. M., Radke, K. L., Hussmann, J., Malik, H., Uelwer, T., Voit, D., Frahm, J., Wittsack, H. J., Harmeling, S., Pillekamp, F. & Klee, D. Pediatr Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35353211
Increased cardiovascular risk in boys born with hypospadias: intriguing observations and remaining questions. Krankel, N. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35352117
Detection of cardiac apoptosis by [(18)F]ML-10 in a mouse model of permanent LAD ligation. Fischer, M., Olivier, J., Lindner, S., Zacherl, M. J., Massberg, S., Bartenstein, P., Ziegler, S., Brendel, M., Lehner, S., Boening, G. & Todica, A. Mol Imaging Biol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35352214
Hemodynamic Effects of Sacubitril/Valsartan in Patients with Reduced Left Ventricular Ejection Fraction Over 24 Months: A Retrospective Study. Abumayyaleh, M., Demmer, J., Krack, C., Pilsinger, C., El-Battrawy, I., Behnes, M., Aweimer, A., Mugge, A., Lang, S. & Akin, I. Am J Cardiovasc Drugs (2022). https://www.ncbi.nlm.nih.gov/pubmed/35353351
Cohort Profile Update: The Study of Health in Pomerania (SHIP). Volzke, H., Schossow, J., Schmidt, C. O., Jurgens, C., Richter, A., Werner, A., Werner, N., Radke, D., Teumer, A., Ittermann, T., Schauer, B., Henck, V., Friedrich, N., Hannemann, A., Winter, T., Nauck, M., Dorr, M., Bahls, M., Felix, S. B., Stubbe, B. et al. Int J Epidemiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35348705
Long-term impact of the metabolic status on weight loss-induced health benefits. Soll, D., Gawron, J., Pletsch-Borba, L., Spranger, J. & Mai, K. Nutr Metab (Lond) 19, 25 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35346256
[Long-term course of heart disease: How can psychosocial care be improved?]. Ladwig, K. H., Lurz, J. & Lukaschek, K. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65, 481-487 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35347347
Feasibility, Acceptability, and Preliminary Efficacy of a Positive Psychology Intervention in Patients With Coronary Heart Disease: A Randomized Controlled Trial. Sadlonova, M., Kermani, M. B., Huffman, J. C., Nikrahan, G. R., Sadeghi, M. & Celano, C. M. J Acad Consult Liaison Psychiatry (2022). https://www.ncbi.nlm.nih.gov/pubmed/35342036
[Analytical Quality of Glucose Measurements in Germany]. Freckmann, G., Heinemann, L., Pleus, S., Petersmann, A., Kaiser, P. & Nauck, M. Dtsch Med Wochenschr 147, 407-413 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35345048
Transcatheter mitral valve implantation in the ongoing structural heart revolution. Sa, M. P., Ramlawi, B., Gray, W. A., Malin, J. H., Van den Eynde, J., Sicouri, S., Torregrossa, G., Klein, C., Heil, E., Sundermann, S. H., Emmerich, A., Kempfert, J., Kofler, M., Falk, V., Unbehaun, A. & Van Praet, K. M. J Card Surg 37, 1691-1704 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35340080
COVID-19-associated cardiac pathology at post-mortem evaluation: A Collaborative systematic Review. Almamlouk, R., Kashour, T., Obeidat, S., Bois, M. C., Maleszewski, J. J., Omrani, O. A., Tleyjeh, R., Berbari, E., Chakhachiro, Z., Zein-Sabatto, B., Gerberi, D., Tleyjeh, I. M. & Cardiac Autopsy in, C.-S. G. Clin Microbiol Infect (2022). https://www.ncbi.nlm.nih.gov/pubmed/35339672
Characteristics and outcomes of patients screened for transcatheter mitral valve implantation: 1-year results from the CHOICE-MI registry. Ben Ali, W., Ludwig, S., Duncan, A., Weimann, J., Nickenig, G., Tanaka, T., Coisne, A., Vincentelli, A., Makkar, R., Webb, J. G., Akodad, M., Muller, D. W. M., Praz, F., Wild, M. G., Hausleiter, J., Goel, S. S., von Ballmoos, M. W., Denti, P., Chehab, O., Redwood, S. et al. Eur J Heart Fail(2022). https://www.ncbi.nlm.nih.gov/pubmed/35338542
Effects of Apolipoprotein E polymorphism on carotid intima-media thickness, incident myocardial infarction and incident stroke. Pitchika, A., Markus, M. R. P., Schipf, S., Teumer, A., Van der Auwera, S., Nauck, M., Dorr, M., Felix, S., Grabe, H. J., Volzke, H. & Ittermann, T. Sci Rep 12, 5142 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35332187
Fractal analysis of 4D dynamic myocardial stress-CT perfusion imaging differentiates micro- and macrovascular ischemia in a multi-center proof-of-concept study. Michallek, F., Nakamura, S., Ota, H., Ogawa, R., Shizuka, T., Nakashima, H., Wang, Y. N., Ito, T., Sakuma, H., Dewey, M. & Kitagawa, K. Sci Rep 12, 5085 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35332236
Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice. Jensen, M., Muller, C., Hubner, N., Patone, G., Saar, K., Choe, C. U., Schwedhelm, E. & Zeller, T. Sci Rep 12, 5108 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35332188
Cardiac remodelling - Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology. Gonzalez, A., Richards, A. M., de Boer, R. A., Thum, T., Arfsten, H., Hulsmann, M., Falcao-Pires, I., Diez, J., Foo, R. S. Y., Chan, M. Y., Aimo, A., Anene-Nzelu, C. G., Abdelhamid, M., Adamopoulos, S., Anker, S. D., Belenkov, Y., Gal, T. B., Cohen-Solal, A., Bohm, M., Chioncel, O. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35334137
Responder analysis for improvement in 6-min walk test with ferric carboxymaltose in patients with heart failure with reduced ejection fraction and iron deficiency. Anker, S. D., Ponikowski, P., Khan, M. S., Friede, T., Jankowska, E. A., Fabien, V., Goehring, U. M., Metra, M., Pina, I. L., Coats, A. J. S., Rosano, G., Dorigotti, F., Comin-Colet, J., Van Veldhuisen, D. J., Filippatos, G. S. & Butler, J. Eur J Heart Fail(2022). https://www.ncbi.nlm.nih.gov/pubmed/35334136
Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor. Warwick, T., Schulz, M. H., Gilsbach, R., Brandes, R. P. & Seuter, S. Nucleic Acids Res 50, 3745-3763 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35325193
Risk-related short-term clinical outcomes after transcatheter aortic valve implantation and their impact on early mortality: an analysis of claims-based data from Germany. Schofer, N., Jeschke, E., Kroger, J., Baberg, H., Falk, V., Gummert, J. F., Hamm, C. W., Mockel, M., Gossling, A., Malzahn, J., Gunster, C. & Blankenberg, S. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35325270
Brugada Syndrome: Different Experimental Models and the Role of Human Cardiomyocytes From Induced Pluripotent Stem Cells. Li, Y., Lang, S., Akin, I., Zhou, X. & El-Battrawy, I. J Am Heart Assoc 11, e024410 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35322667
Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts premature death in acute coronary syndromes. Kraler, S., Wenzl, F. A., Georgiopoulos, G., Obeid, S., Liberale, L., von Eckardstein, A., Muller, O., Mach, F., Raber, L., Losdat, S., Schmiady, M. O., Stellos, K., Stamatelopoulos, K., Camici, G. G., Srdic, A., Paneni, F., Akhmedov, A. & Luscher, T. F. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35325132
Risk Factors, Subsequent Disease Onset, and Prognostic Impact of Myocardial Infarction and Atrial Fibrillation. Camen, S., Csengeri, D., Geelhoed, B., Niiranen, T., Gianfagna, F., Vishram-Nielsen, J. K., Costanzo, S., Soderberg, S., Vartiainen, E., Borschel, C. S., Donati, M. B., Lochen, M. L., Ojeda, F. M., Kontto, J., Mathiesen, E. B., Jensen, S., Koenig, W., Kee, F., de Gaetano, G., Zeller, T. et al. J Am Heart Assoc 11, e024299 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35322680
Weight loss did not modify macronutrient specific response of hormones and satiety in overweight and obese people without metabolic disease - results from a clinical trial. Li, L., Decker, A. M., Stobaus, N., Beer, F., Grittner, U., Spranger, J. & Mai, K. Clin Nutr 41, 948-957 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35303516
Predicting visceral adipose tissue in older adults: A pilot clinical study. Perna, S., Faragli, A., Spadaccini, D., Peroni, G., Gasparri, C., Al-Mannai, M. A., Casali, P. M., La Porta, E., Kelle, S., Alogna, A. & Rondanelli, M. Clin Nutr 41, 810-816 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35263690
Role of Reticulated Platelets in Cardiovascular Disease. Bongiovanni, D., Han, J., Klug, M., Kirmes, K., Viggiani, G., von Scheidt, M., Schreiner, N., Condorelli, G., Laugwitz, K. L. & Bernlochner, I. Arterioscler Thromb Vasc Biol, ATVBAHA121316244 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35321562
TAVI in patients with low-flow low-gradient aortic stenosis-short-term and long-term outcomes. Steffen, J., Reissig, N., Andreae, D., Beckmann, M., Haum, M., Fischer, J., Theiss, H., Braun, D., Orban, M., Rizas, K., Sadoni, S., Nabauer, M., Peterss, S., Hausleiter, J., Massberg, S. & Deseive, S. Clin Res Cardiol(2022). https://www.ncbi.nlm.nih.gov/pubmed/35320407
Progressive machine-based resistance training for prevention and treatment of sarcopenia in the oldest old: A systematic review and meta-analysis. Mende, E., Moeinnia, N., Schaller, N., Weiss, M., Haller, B., Halle, M. & Siegrist, M. Exp Gerontol, 111767 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35318104
Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study. Just, I. A., Fries, D., Loewe, S., Falk, V., Cesarovic, N., Edelmann, F., Feuerstein, A., Haufe, F. L., Xiloyannis, M., Riener, R. & Schoenrath, F. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35320878
Sample size calculation for the augmented logrank test in randomized clinical trials. Hattori, S., Komukai, S. & Friede, T. Stat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35319100
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS). Haffke, M., Freitag, H., Rudolf, G., Seifert, M., Doehner, W., Scherbakov, N., Hanitsch, L., Wittke, K., Bauer, S., Konietschke, F., Paul, F., Bellmann-Strobl, J., Kedor, C., Scheibenbogen, C. & Sotzny, F. J Transl Med 20, 138 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35317812
Challenges in the conduct of randomised controlled trials in cardiogenic shock complicating acute myocardial infarction. Freund, A., Desch, S. & Thiele, H. J Geriatr Cardiol 19, 125-129 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35317398
In vivo and ex vivo electrophysiological study of the mouse heart to characterize the cardiac conduction system, including atrial and ventricular vulnerability. Hennis, K., Rotzer, R. D., Rilling, J., Wu, Y., Thalhammer, S. B., Biel, M., Wahl-Schott, C. & Fenske, S. Nat Protoc (2022). https://www.ncbi.nlm.nih.gov/pubmed/35314849
Different activation of MAPKs and Akt/GSK3beta after preload vs. afterload elevation. Hartmann, N., Preuss, L., Mohamed, B. A., Schnelle, M., Renner, A., Hasenfuss, G. & Toischer, K. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35315235
Empagliflozin in patients with type 2 diabetes mellitus and chronic obstructive pulmonary disease. Anker, S. D., Sander, L. E., Fitchett, D. H., Zinman, B., Pernille Ofstad, A., Wanner, C., Vedin, O., Lauer, S., Verma, S., Yaggi, H. K. & Inzucchi, S. E. Diabetes Res Clin Pract, 109837 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35314257
The Role of Glutamine and Glutaminase in Pulmonary Hypertension. Wang, S., Yan, Y., Xu, W. J., Gong, S. G., Zhong, X. J., An, Q. Y., Zhao, Y. L., Liu, J. M., Wang, L., Yuan, P. & Jiang, R. Front Cardiovasc Med 9, 838657 (2022).
Platelets, Thromboinflammation and Neurovascular Disease. Sun, Y. & Langer, H. F. Front Immunol 13, 843404 (2022).
A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats. Sang, P., Kucherenko, M. M., Yao, J., Li, Q., Simmons, S., Kuebler, W. M. & Knosalla, C. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35311828
Targeting platelet-derived CXCL12 impedes arterial thrombosis. Leberzammer, J., Agten, S. M., Blanchet, X., Duan, R., Ippel, H., Megens, R. T. A., Schulz, C., Aslani, M., Duchene, J., Doring, Y., Jooss, N. J., Zhang, P., Brandl, R., Stark, K., Siess, W., Jurk, K., Heemskerk, J. W. M., Hackeng, T. M., Mayo, K. H., Weber, C. et al. Blood (2022). https://www.ncbi.nlm.nih.gov/pubmed/35313337
Coronary artery disease, left ventricular function and cardiac biomarkers determine all-cause mortality in cancer patients-a large monocenter cohort study. Finke, D., Heckmann, M. B., Wilhelm, S., Entenmann, L., Hund, H., Bougatf, N., Katus, H. A., Frey, N. & Lehmann, L. H. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35312818
Stroke after transcatheter aortic valve replacement: A severe complication with low predictability. Eschenbach, L. K., Erlebach, M., Deutsch, M. A., Ruge, H., Bleiziffer, S., Holzer, L., Krane, M., Voss, S., Lange, R. & Burri, M. Catheter Cardiovasc Interv (2022). https://www.ncbi.nlm.nih.gov/pubmed/35312220
Svep1 stabilises developmental vascular anastomosis in reduced flow conditions. Coxam, B., Collins, R. T., Hussmann, M., Huisman, Y., Meier, K., Jung, S., Bartels-Klein, E., Szymborska, A., Finotto, L., Helker, C. S. M., Stainier, D. Y. R., Schulte-Merker, S. & Gerhardt, H. Development 149 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35312765
Genetically determined reproductive aging and coronary heart disease: a bidirectional two-sample Mendelian Randomization. Dam, V., Onland-Moret, N. C., Burgess, S., Chirlaque, M. D., Peters, S. A. E., Schuit, E., Tikk, K., Weiderpass, E., Oliver-Williams, C., Wood, A. M., Tjonneland, A., Dahm, C. C., Overvad, K., Boutron-Ruault, M. C., Schulze, M. B., Trichopoulou, A., Ferrari, P., Masala, G., Krogh, V., Tumino, R. et al. J Clin Endocrinol Metab (2022). https://www.ncbi.nlm.nih.gov/pubmed/35306566
Clinical characteristics and outcome of biopsy-proven myocarditis in children - Results of the German prospective multicentre registry "MYKKE". Seidel, F., Opgen-Rhein, B., Rentzsch, A., Boehne, M., Wannenmacher, B., Boecker, D., Reineker, K., Grafmann, M., Wiegand, G., Hecht, T., Kiski, D., Fischer, M., Papakostas, K., Ruf, B., Kramp, J., Khalil, M., Kaestner, M., Steinmetz, M., Fischer, G., Ozcan, S. et al. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304189
Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Santovito, D. & Weber, C. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304600
Does social support prevent suicidal ideation in women and men? Gender-sensitive analyses of an important protective factor within prospective community cohorts. Otten, D., Ernst, M., Tibubos, A. N., Brahler, E., Fleischer, T., Schomerus, G., Wild, P. S., Zoller, D., Binder, H., Kruse, J., Johar, H., Atasoy, S., Grabe, H. J., Ladwig, K. H., Munzel, T., Volzke, H., Konig, J. & Beutel, M. E. J Affect Disord 306, 157-166 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304236
Single-centre outcome of extracorporeal membrane oxygenation after the neonatal Norwood procedure. Mayr, B., Kido, T., Holder, S., Wallner, M., Vodiskar, J., Strbad, M., Ruf, B., Hager, A., Ewert, P., Horer, J., Lange, R. & Ono, M. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35304610
Sudden cardiac death while waiting: do we need the wearable cardioverter-defibrillator? Israel, C., Staudacher, I., Leclercq, C., Botto, G. L., Scherr, D., Fach, A., Duru, F., Zylla, M. M., Katus, H. A. & Thomas, D. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35305126
MicroRNAs Regulate TASK-1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation. Wiedmann, F., Kraft, M., Kallenberger, S., Buscher, A., Paasche, A., Blochberger, P. L., Seeger, T., Javorszky, N., Warnecke, G., Arif, R., Kremer, J., Karck, M., Frey, N. & Schmidt, C. J Am Heart Assoc, e023472 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35301863
Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus-specific. Muehleman, D. L., Crocini, C., Swearingen, A. R., Ozeroff, C. D. & Leinwand, L. A. Am J Physiol Heart Circ Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35302880
Impact of Right Ventricular Pressure Load After Repair of Tetralogy of Fallot. Latus, H., Stammermann, J., Voges, I., Waschulzik, B., Gutberlet, M., Diller, G. P., Schranz, D., Ewert, P., Beerbaum, P., Kuhne, T., Sarikouch, S. & German Competence Network for Congenital Heart Defects Investigators. J Am Heart Assoc, e022694 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35301850
The normalized slope conductance as a tool for quantitative analysis of current-voltage relations. Hermann, C., Treder, A., Naher, M., Geiseler, R., Gudermann, T., Mederos, Y. S. M. & Storch, U. Biophys J(2022). https://www.ncbi.nlm.nih.gov/pubmed/35300969
Association of MRI-based adrenal gland volume and impaired glucose metabolism in a population-based cohort study. Askani, E., Rospleszcz, S., Lorbeer, R., Kulka, C., von Kruchten, R., Muller-Peltzer, K., Hasic, D., Kellner, E., Reisert, M., Rathmann, W., Peters, A., Schlett, C. L., Bamberg, F. & Storz, C. Diabetes Metab Res Rev, e3528 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35303389
Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and skeletal muscle contractility. Adams, V., Schauer, A., Augstein, A., Kirchhoff, V., Draskowski, R., Jannasch, A., Goto, K., Lyall, G., Mannel, A., Barthel, P., Mangner, N., Winzer, E. B., Linke, A. & Labeit, S. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35301823
Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets. Wolf, R., Grammbauer, S., Palankar, R., Tolksdorf, C., Moritz, E., Bohm, A., Hasan, M., Hafkemeyer, A., Greinacher, A., Tzvetkov, M. V., Rauch, B. H. & Jedlitschky, G. Haematologica (2022). https://www.ncbi.nlm.nih.gov/pubmed/35295075
A systematic review and meta-analysis of the cerebrovascular event incidence after transcatheter aortic valve implantation. Meertens, M. M., Macherey, S., Asselberghs, S., Lee, S., Schipper, J. H., Mees, B., Eitel, I., Baldus, S., Frerker, C. & Schmidt, T. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35298700
TAVR or SAVR? What can we learn from a pooled meta-analysis of reconstructed time to event data? Lange, R., Vitanova, K. & Ruge, H. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35298634
Dronedarone for the Treatment of Atrial Fibrillation with Concomitant Heart Failure with Preserved and Mildly Reduced Ejection Fraction: Post-Hoc Analysis of the ATHENA Trial. Vaduganathan, M., Piccini, J. P., Camm, A. J., Crijns, H., Anker, S. D., Butler, J., Stewart, J., Braceras, R., Albuquerque, A. P., Wieloch, M. & Hohnloser, S. H. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35293087
Simultaneous assessment of spontaneous cage activity and voluntary wheel running in group-housed mice. Reuser, A., Wenzel, K., Felix, S. B., Dorr, M., Bahls, M. & Konemann, S. Sci Rep 12, 4444 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35292692
Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure. Pagnesi, M., Adamo, M., Sama, I. E., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., Inciardi, R. M., Lang, C. C., Lombardi, C. M., Ng, L. L., Ponikowski, P., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Voors, A. A. & Metra, M. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35294624
Mind and body interventions in cardiology : The importance of the brain-heart connection. Lurz, J. & Ladwig, K. H. Herz 47, 103-109 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35292838
A system for real-time multivariate feature combination of endoscopic mitral valve simulator training data. Fuchs, R., Van Praet, K. M., Bieck, R., Kempfert, J., Holzhey, D., Kofler, M., Borger, M. A., Jacobs, S., Falk, V. & Neumuth, T. Int J Comput Assist Radiol Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35294716
The epigenetic enzyme DOT1L orchestrates vascular smooth muscle cell-monocyte crosstalk and protects against atherosclerosis via the NF-kappaB pathway. Farina, F. M., Serio, S., Hall, I. F., Zani, S., Cassanmagnago, G. A., Climent, M., Civilini, E., Condorelli, G., Quintavalle, M. & Elia, L. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35292818
Heart-Type Fatty Acid Binding Protein, Cardiovascular Outcomes, and Death: Findings From the German CKD Cohort Study. Schneider, M. P., Schmid, M., Nadal, J., Wanner, C., Krane, V., Floege, J., Saritas, T., Busch, M., Sitter, T., Friedrich, N., Stockmann, H., Meiselbach, H., Nauck, M., Kronenberg, F., Eckardt, K. U. & Investigators, G. S. Am J Kidney Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35288215
Determination of scar area using native and post-contrast T1 mapping: Agreement with late gadolinium enhancement. Kolentinis, M., Carerj, L. M., Vidalakis, E., Giokoglu, E., Martin, S., Arendt, C., Vogl, T. J., Nagel, E. & Puntmann, V. O. Eur J Radiol 150, 110242 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35290909
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver. Kaltenbacher, T., Loprich, J., Maresch, R., Weber, J., Muller, S., Oellinger, R., Gross, N., Griger, J., de Andrade Kratzig, N., Avramopoulos, P., Ramanujam, D., Brummer, S., Widholz, S. A., Barthel, S., Falcomata, C., Pfaus, A., Alnatsha, A., Mayerle, J., Schmidt-Supprian, M., Reichert, M. et al. Nat Protoc (2022). https://www.ncbi.nlm.nih.gov/pubmed/35288718
Plasma circulating micro-RNAs associated with alexithymia reflect a high overlap on neuropsychiatric outcomes. Van der Auwera, S., Ameling, S., Nauck, M., Volzke, H., Volker, U. & Grabe, H. J. J Affect Disord 305, 206-212 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35283179
Recommendations in pre-procedural imaging assessment for transcatheter aortic valve implantation intervention: Italian Society of Cardiology (SIC)-Italian Society of Medical and Interventional Radiology (SIRM) position paper part 1 (Clinical Indication and Basic Technical Aspects, Heart Team, Role of Echocardiography). Pontone, G., Marano, R., Agricola, E., Alushi, B., Bartorelli, A., Cameli, M., Carrabba, N., Esposito, A., Faletti, R., Francone, M., Galea, N., Golino, P., Guglielmo, M., Palmisano, A., Petronio, S., Petulla, M., Pradella, S., Ribichini, F., Romeo, F., Russo, V. et al. J Cardiovasc Med (Hagerstown) 23, 216-227 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35287156
Association between hepatic iron overload assessed by magnetic resonance imaging and glucose intolerance states in the general population. Naeem, M., Schipf, S., Bulow, R., Werner, N., Dorr, M., Lerch, M. M., Kuhn, J. P., Rathmann, W., Nauck, M., Paulista Markus, M. R., Targher, G., Ittermann, T. & Volzke, H. Nutr Metab Cardiovasc Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35282980
Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy. Kaur, N., Ruiz-Velasco, A., Raja, R., Howell, G., Miller, J. M., Abouleisa, R. R. E., Ou, Q., Mace, K., Hille, S. S., Frey, N., Binder, P., Smith, C. P., Fachim, H., Soran, H., Swanton, E., Mohamed, T. M. A., Muller, O. J., Wang, X., Chernoff, J., Cartwright, E. J. et al. iScience 25, 103973 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35281739
Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication. Froese, N., Cordero, J., Abouissa, A., Trogisch, F. A., Grein, S., Szaroszyk, M., Wang, Y., Gigina, A., Korf-Klingebiel, M., Bosnjak, B., Davenport, C. F., Wiehlmann, L., Geffers, R., Riechert, E., Jurgensen, L., Boileau, E., Lin, Y., Dieterich, C., Forster, R., Bauersachs, J. et al. iScience 25, 103965 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35281736
Chronic isoprenaline/phenylephrine vs. exclusive isoprenaline stimulation in mice: critical contribution of alpha1-adrenoceptors to early cardiac stress responses. Dewenter, M., Pan, J., Knodler, L., Tzschockel, N., Henrich, J., Cordero, J., Dobreva, G., Lutz, S., Backs, J., Wieland, T. & Vettel, C. Basic Res Cardiol 117, 15 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35286475
Transcatheter Tricuspid Valve Replacement With the EVOQUE System: 1-Year Outcomes of a Multicenter, First-in-Human Experience. Webb, J. G., Chuang, A. M., Meier, D., von Bardeleben, R. S., Kodali, S. K., Smith, R. L., Hausleiter, J., Ong, G., Boone, R., Ruf, T., George, I., Szerlip, M., Nabauer, M., Ali, F. M., Moss, R., Kreidel, F., Bapat, V., Schnitzler, K., Ye, J., Wild, M. et al. JACC Cardiovasc Interv 15, 481-491 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35272772
Effect of Leisure Sports on Exercise Capacity and Quality of Life in Patients with a Fontan Circulation. Niemann, A., Rinne, K., Hansen, J. H., Scheewe, J., Uebing, A. & Voges, I. Am J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35279276
Health Status Improvement with Ferric Carboxymaltose in Heart Failure with Reduced Ejection Fraction and Iron Deficiency. Butler, J., Khan, M. S., Friede, T., Jankowska, E. A., Fabien, V., Goehring, U. M., Dorigotti, F., Metra, M., Pina, I. L., Coats, A. J., Rosano, G., Comin-Colet, J., Van Veldhuisen, D. J., Filippatos, G. S., Anker, S. D. & Ponikowski, P. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35279929
Use of evidence-based therapy in heart failure with reduced ejection fraction across age strata. Stolfo, D., Lund, L. H., Becher, P. M., Orsini, N., Thorvaldsen, T., Benson, L., Hage, C., Dahlstrom, U., Sinagra, G. & Savarese, G. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35278267
Surrogate markers of gut dysfunction are related to heart failure severity and outcome - from the BIOSTAT-CHF consortium. Israr, M. Z., Zhan, H., Salzano, A., Voors, A. A., Cleland, J. G., Anker, S. D., Metra, M., van Veldhuisen, D. J., Lang, C. C., Zannad, F., Samani, N. J., Ng, L. L., Suzuki, T. & investigators, B.-C. Am Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35278373
Endoaortic Balloon Occlusion During Minimally Invasive Mitral Valve Surgery. Van Praet, K. M., Kofler, M., Sundermann, S. H. & Kempfert, J. Innovations (Phila), 15569845221083047 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35275021
To quantify or not to quantify, that is the question: Semi-quantitative vs. visual analysis of Rb-82 myocardial perfusion imaging PET. Rischpler, C., Kersting, D. & Nekolla, S. G. J Nucl Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35274212
H-ABC- and dystonia-causing TUBB4A mutations show distinct pathogenic effects. Krajka, V., Vulinovic, F., Genova, M., Tanzer, K., Jijumon, A. S., Bodakuntla, S., Tennstedt, S., Mueller-Fielitz, H., Meier, B., Janke, C., Klein, C. & Rakovic, A. Sci Adv 8, eabj9229 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35275727
Retraction notice to "Astragalus polysaccharide ameliorates lipopolysaccharide-induced cell injury in ATDC5 cells via miR-92a/KLF4 mediation" [Biomed. Pharmacother. 118 (2019) 109180]. Fan, L., Li, M., Cao, F. Y., Zeng, Z. W., Li, X. B., Ma, C., Ru, J. T. & Wu, X. J. Biomed Pharmacother 148, 112780 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35272895
Regulation of Ion Channel Function in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Cancer Cell Secretion Through DNA Methylation. Zhong, R., Zhang, F., Yang, Z., Li, Y., Xu, Q., Lan, H., Lang, S., Cyganek, L., Burgermeister, E., El-Battrawy, I., Zhou, X., Akin, I. & Borggrefe, M. Front Cardiovasc Med 9, 839104 (2022).
Tph2 Gene Expression Defines Ethanol Drinking Behavior in Mice. Zaniewska, M., Mosienko, V., Bader, M. & Alenina, N. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35269497
Chrono-pharmacology-based antiplatelet therapy for acute myocardial infarction. Tual-Chalot, S. & Stellos, K. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35266001
Mitral valve prolapse: will genetics finally solve the puzzle? Trenkwalder, T. & Krane, M. Eur Heart J(2022). https://www.ncbi.nlm.nih.gov/pubmed/35265976
Impact of energy drink versus coffee consumption on periodic repolarization dynamics: an interventional study. Schuttler, D., Rudi, W. S., Bauer, A., Hamm, W. & Brunner, S. Eur J Nutr (2022). https://www.ncbi.nlm.nih.gov/pubmed/35266046
Angiotensin Converting Enzyme Inhibitors versus Receptor Blockers in Patients with Ventricular Tachyarrhythmias. Schupp, T., Behnes, M., Abumayyaleh, M., Weidner, K., Mashayekhi, K., Bertsch, T. & Akin, I. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35268553
Cardiac Myxomas Resembling Malignant Neoplasia: Incidentally Diagnosed vs. Cerebral Embolized Myxomas. Salem, M., Hillmer, J., Friedrich, C., Panholzer, B., Saad, M., Salem, M., Frank, D., Ernst, M., Maetzler, W., Puehler, T., Lutter, G., Schoeneich, F., Haneya, A., Cremer, J. & Schoettler, J. Cancers (Basel) 14(2022). https://www.ncbi.nlm.nih.gov/pubmed/35267419
Imaging of arrhythmia: Real-time cardiac magnetic resonance imaging in atrial fibrillation. Laubrock, K., von Loesch, T., Steinmetz, M., Lotz, J., Frahm, J., Uecker, M. & Unterberg-Buchwald, C. Eur J Radiol Open 9, 100404 (2022).
Local dose rate effects in implantable cardioverter-defibrillators with flattening filter free and flattened photon radiation. Gauter-Fleckenstein, B., Tulumen, E., Rudic, B., Borggrefe, M., Polednik, M. & Fleckenstein, J. Strahlenther Onkol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35267050
Extracorporeal Membrane Oxygenation in Infarct-Related Cardiogenic Shock. Freund, A., Desch, S., Poss, J., Sulimov, D., Sandri, M., Majunke, N. & Thiele, H. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35268347
A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. El-Sammak, H., Yang, B., Guenther, S., Chen, W., Marin-Juez, R. & Stainier, D. Y. R. Circ Res, CIRCRESAHA121319929 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35264012
Single-cell technologies to decipher cardiovascular diseases. Abplanalp, W. T., Tucker, N. & Dimmeler, S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35265972
Impact of baseline left ventricular ejection fraction on long-term outcomes in cardiac contractility modulation therapy. Yucel, G., Fastner, C., Hetjens, S., Toepel, M., Schmiel, G., Yazdani, B., Husain-Syed, F., Liebe, V., Rudic, B., Akin, I., Borggrefe, M. & Kuschyk, J. Pacing Clin Electrophysiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35262210
The effects of common genetic variation in 96 genes involved in thyroid hormone regulation on TSH and FT4 concentrations. Sterenborg, R., Galesloot, T. E., Teumer, A., Netea-Maier, R. T., Speed, D., Meima, M. E., Visser, W. E., Smit, J. W. A., Peeters, R. P. & Medici, M. J Clin Endocrinol Metab (2022). https://www.ncbi.nlm.nih.gov/pubmed/35262175
A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease. Shomroni, O., Sitte, M., Schmidt, J., Parbin, S., Ludewig, F., Yigit, G., Zelarayan, L. C., Streckfuss-Bomeke, K., Wollnik, B. & Salinas, G. Sci Rep 12, 4091 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35260714
Pharmacological treatment options for heart failure with reduced ejection fraction: A 2022 update. Hellenkamp, K., Nolte, K. & von Haehling, S. Expert Opin Pharmacother, 1-8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35260016
Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients. Haupt, L. P., Rebs, S., Maurer, W., Hubscher, D., Tiburcy, M., Pabel, S., Maus, A., Kohne, S., Tappu, R., Haas, J., Li, Y., Sasse, A., Santos, C. C. X., Dressel, R., Wojnowski, L., Bunt, G., Mobius, W., Shah, A. M., Meder, B., Wollnik, B. et al. Basic Res Cardiol 117, 13 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35260914
Evolution of Artificial Intelligence-Powered Technologies in Biomedical Research and Healthcare. Diaz-Flores, E., Meyer, T. & Giorkallos, A. Adv Biochem Eng Biotechnol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35262750
Clinical frailty, and not features of acute infection, is associated with late mortality in COVID-19: a retrospective cohort study. Vlachogiannis, N. I., Baker, K. F., Georgiopoulos, G., Lazaridis, C., van der Loeff, I. S., Hanrath, A. T., Sopova, K., Tual-Chalot, S., Gatsiou, A., Spyridopoulos, I., Stamatelopoulos, K., Duncan, C. J. A. & Stellos, K. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35257497
Missense Variant E1295K of Sodium Channel SCN5A Associated With Recurrent Ventricular Fibrillation and Myocardial Inflammation. Poller, W., Escher, F., Haas, J., Heidecker, B., Schultheiss, H. P., Attanasio, P., Skurk, C., Haghikia, A., Meder, B. & Klaassen, S. JACC Case Rep 4, 280-286 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35257103
Carotid Intima-Media Thickness Percentiles in Adolescence and Young Adulthood and Their Association With Obesity and Hypertensive Blood Pressure in a Population Cohort. Neuhauser, H. K., Buschges, J., Schaffrath Rosario, A., Schienkiewitz, A., Sarganas, G., Konigstein, K., Schweizer, D. & Schmidt-Trucksass, A. Hypertension, HYPERTENSIONAHA12118521 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35255707
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing. Kogan, P. S., Wirth, F., Tomar, A., Darr, J., Teperino, R., Lahm, H., Dressen, M., Puluca, N., Zhang, Z., Neb, I., Beck, N., Luzius, T., de la Osa de la Rosa, L., Gartner, K., Huls, C., Zeidler, R., Ramanujam, D., Engelhardt, S., Wenk, C., Holdt, L. M. et al. Basic Res Cardiol 117, 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35258704
How many molecules of mitochondrial complex I are in a cell? Ansari, F., Yoval, B., Niatsetskaya, Z., Ten, V., Wittig, I. & Galkin, A. Anal Biochem, 114646 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35259403
Targeting the CCL2-CCR2 axis for atheroprotection. Georgakis, M. K., Bernhagen, J., Heitman, L. H., Weber, C. & Dichgans, M. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35253053
Generation of heterozygous (MRli003-A-3) and homozygous (MRli003-A-4) TRPM4 knockout human iPSC lines. Zhang, F., Meier, A. B., Lipp, P., Laugwitz, K. L., Dorn, T. & Moretti, A. Stem Cell Res 60, 102731 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35245852
Isotropic 3D compressed sensing (CS) based sequence is comparable to 2D-LGE in left ventricular scar quantification in different disease entities. Fenski, M., Grandy, T. H., Viezzer, D., Kertusha, S., Schmidt, M., Forman, C. & Schulz-Menger, J. Int J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35243574
[Morphological and functional diagnostics of coronary artery disease by computed tomography]. Baumann, S., Overhoff, D., Tesche, C., Korosoglou, G., Kelle, S., Nassar, M., Buss, S. J., Andre, F., Renker, M., Schoepf, U. J., Akin, I., Waldeck, S., Schoenberg, S. O. & Lossnitzer, D. Herz (2022). https://www.ncbi.nlm.nih.gov/pubmed/35244729
Durability of benefit after transcatheter tricuspid valve intervention: insights from actigraphy. Stocker, T. J., Cohen, D. J., Arnold, S. V., Sommer, S., Braun, D., Stolz, L., Hertell, H., Weckbach, L. T., Wild, M. G., Doldi, P., Orban, M., Orban, M., Deseive, S., Higuchi, S., Massberg, S., Nabauer, M. & Hausleiter, J. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35239253
CT or Invasive Coronary Angiography in Stable Chest Pain. Group, D. T., Maurovich-Horvat, P., Bosserdt, M., Kofoed, K. F., Rieckmann, N., Benedek, T., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Stechovsky, C., Sakalyte, G., Cemerlic Adic, N., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M. et al. N Engl J Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35240010
Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques. Egea, V., Megens, R. T. A., Santovito, D., Wantha, S., Brandl, R., Siess, W., Khani, S., Soehnlein, O., Bartelt, A., Weber, C. & Ries, C. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35238350
Visceral and renal malperfusion syndromes in acute aortic dissection type A: the fate of the branch vessel. Buech, J., Radner, C., Fabry, T. G., Horke, K. M., Ali, A., Saha, S., Hagl, C., Pichlmaier, M. A. & Peterss, S. J Cardiovasc Surg (Torino) (2022). https://www.ncbi.nlm.nih.gov/pubmed/35238524
Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study. Portilla-Fernandez, E., Klarin, D., Hwang, S. J., Biggs, M. L., Bis, J. C., Weiss, S., Rospleszcz, S., Natarajan, P., Hoffmann, U., Rogers, I. S., Truong, Q. A., Volker, U., Dorr, M., Bulow, R., Criqui, M. H., Allison, M., Ganesh, S. K., Yao, J., Waldenberger, M., Bamberg, F. et al. Hum Mol Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35234888
Links between ectopic and abdominal fat and systemic inflammation: New insights from the SHIP-Trend study. Ponce-de-Leon, M., Hannemann, A., Linseisen, J., Nauck, M., Lerch, M. M., Bulow, R., Volzke, H., Friedrich, N., Kassubek, J., Muller, H. P., Baumeister, S. E. & Meisinger, C. Dig Liver Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35232676
From atherosclerosis to myocardial infarction - a process-oriented model investigating the role of risk factors. Simonetto, C., Heier, M., Peters, A., Kaiser, J. C. & Rospleszcz, S. Am J Epidemiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35231928
DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. Seredinski, S., Boos, F., Gunther, S., Oo, J. A., Warwick, T., Izquierdo Ponce, J., Lillich, F. F., Proschak, E., Knapp, S., Gilsbach, R., Pfluger-Muller, B., Brandes, R. P. & Leisegang, M. S. Mol Ther Nucleic Acids 27, 1023-1035 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35228897
Short-term effects of cold spells on plasma viscosity: Results from the KORA cohort study in Augsburg, Germany. Ni, W., Schneider, A., Wolf, K., Zhang, S., Chen, K., Koenig, W., Peters, A. & Breitner, S. Environ Pollut 302, 119071 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35231540
RGS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes. Levay, M. K., Krobert, K. A., Vogt, A., Ahmad, A., Jungmann, A., Neuber, C., Pasch, S., Hansen, A., Muller, O. J., Lutz, S. & Wieland, T. Basic Res Cardiol 117, 8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35230541
Thrombus formation at the inflow cannula of continuous-flow left ventricular assist devices-A systematic analysis. Kaufmann, F., Hormandinger, C., Knosalla, C., Falk, V. & Potapov, E. Artif Organs(2022). https://www.ncbi.nlm.nih.gov/pubmed/35230721
Ticagrelor Monotherapy or Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation: Per-Protocol Analysis of the GLOBAL LEADERS Trial. Gragnano, F., Zwahlen, M., Vranckx, P., Heg, D., Schmidlin, K., Hamm, C., Steg, P. G., Gargiulo, G., McFadden, E. P., Onuma, Y., Chichareon, P., Benit, E., Mollmann, H., Janssens, L., Leonardi, S., Zurakowski, A., Arrivi, A., Van Geuns, R. J., Huber, K., Slagboom, T.et al. J Am Heart Assoc, e024291 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35229616
Thyroid function, pernicious anemia, and erythropoiesis: a two-sample Mendelian randomization study. Kjaergaard, A. D., Teumer, A., Marouli, E., Deloukas, P., Kus, A., Sterenborg, R., Asvold, B. O., Medici, M. & Ellervik, C. Hum Mol Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35225327
April
Paper of the Month
Do it "RIGHT": HeartMate 3 as Destination Therapy Right Ventricular Assist Device in a Patient With Arrhythmogenic Right Ventricular Cardiomyopathy. Hanuna, M., Kaab, S., Hagl, C. & Mueller, C. S. ASAIO J 69, e46-e48 (2023). www.ncbi.nlm.nih.gov/pubmed/35471649
Endoaortic balloon occlusion in minimally invasive mitral valve surgery. Van Praet, K. M., Nersesian, G., Montagner, M., Akansel, S., Eggert-Doktor, D., Kofler, M., Sundermann, S., Falk, V. & Kempfert, J. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35467092
Percutaneous transseptal transcatheter mitral valve-in-valve implantation under endovascular cerebral protection. Van Praet, K. M., Nersesian, G., Kukucka, M., Heil, E., Kofler, M., Falk, V., Kempfert, J., Klein, C. & Unbehaun, A. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35467091
Case Series of Potential Cardiac Inflammation Associated With Various SARS-CoV-2 Vaccinations Assessed by Cardiac MRI. Jahnke, C., Doeblin, P., Tanacli, R., Witt, U., Schneider, M., Stehning, C., Pieske, B. & Kelle, S. Front Cardiovasc Med 9, 829392 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35463791
Platelet Subtypes in Inflammatory Settings. Hamad, M. A., Krauel, K., Schanze, N., Gauchel, N., Stachon, P., Nuehrenberg, T., Zurek, M. & Duerschmied, D. Front Cardiovasc Med 9, 823549 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35463762
Stroke Complications in Patients Requiring Durable Mechanical Circulatory Support Systems After Extracorporeal Life Support. Saeed, D., Loforte, A., Morshuis, M., Schibilsky, D., Zimpfer, D., Riebandt, J., Pappalardo, F., Attisani, M., Rinaldi, M., Haneya, A., Ramjankhan, F., Donker, D. W., Jorde, U. P., Pacini, D., Otto, W., Stein, J., Lewin, D., Jawad, K., Wieloch, R., Ayala, R. et al. ASAIO J 69, 145-150 (2023). https://www.ncbi.nlm.nih.gov/pubmed/35438667
Formation and Maintenance of the Natural Bypass Vessels of the Brain. Perovic, T., Harms, C. & Gerhardt, H. Front Cardiovasc Med 9, 778773 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35391845
CT-Based Simulation of Left Ventricular Hemodynamics: A Pilot Study in Mitral Regurgitation and Left Ventricle Aneurysm Patients. Obermeier, L., Vellguth, K., Schlief, A., Tautz, L., Bruening, J., Knosalla, C., Kuehne, T., Solowjowa, N. & Goubergrits, L. Front Cardiovasc Med 9, 828556 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35391837
Predictive Value of Two-Dimensional Speckle-Tracking Echocardiography in Patients Undergoing Surgical Ventricular Restoration. Nemchyna, O., Solowjowa, N., Dandel, M., Hrytsyna, Y., Stein, J., Knierim, J., Schoenrath, F., Hennig, F., Falk, V. & Knosalla, C. Front Cardiovasc Med 9, 824467 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35387444
Case Report: Residual Atrial Shunt Lesions in Aging Adults With Congenital Heart Disease: An Underestimated Risk of Stroke? Schneider, M., Dannenberg, V., Opgen-Rhein, B., Berger, F., Pieske, B., Gabriel, H. & Boldt, L. H. Front Cardiovasc Med 9, 847244 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35369334
Acculturation and Anger Expression Among Iranian Migrants in Germany. Gilan, D., Werner, A. M., Hahad, O., Lieb, K., Frankenberg, E. & Bongard, S. Front Psychol 13, 715152 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35369188
A Mixed-Methods Investigation of Medical Follow-Up in Long-Term Childhood Cancer Survivors: What Are the Reasons for Non-Attendance? Ernst, M., Brahler, E., Faber, J., Wild, P. S., Merzenich, H. & Beutel, M. E. Front Psychol 13, 846671 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35369241
Cascaded learning in intravascular ultrasound: coronary stent delineation in manual pullbacks. Wissel, T., Riedl, K. A., Schaefers, K., Nickisch, H., Brunner, F. J., Schnellbaecher, N. D., Blankenberg, S., Seiffert, M. & Grass, M. J Med Imaging (Bellingham) 9, 025001 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360417
Manual Compression versus Suture-Mediated Closure Device Technique for VA-ECMO Decannulation. Scherer, C., Stremmel, C., Lusebrink, E., Stocker, T. J., Stark, K., Schonegger, C., Kellnar, A., Kleeberger, J., Hanuna, M., Petzold, T., Peterss, S., Braun, D., Hausleiter, J., Hagl, C., Massberg, S. & Orban, M. J Interv Cardiol 2022, 9915247 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360094
A Mathematical Model for Electrical Activity in Pig Atrial Tissue. Peris-Yague, V., Rubio, T., Fakuade, F. E., Voigt, N., Luther, S. & Majumder, R. Front Physiol 13, 812535 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360247
A Multimodal Score Accurately Classifies Fontan Failure and Late Mortality in Adult Fontan Patients. Kramer, P., Schleiger, A., Schafstedde, M., Danne, F., Nordmeyer, J., Berger, F. & Ovroutski, S. Front Cardiovasc Med 9, 767503 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360016
Disease Severity in Moderate-to-Severe COVID-19 Is Associated With Platelet Hyperreactivity and Innate Immune Activation. Jakobs, K., Reinshagen, L., Puccini, M., Friebel, J., Wilde, A. B., Alsheik, A., Rroku, A., Landmesser, U., Haghikia, A., Krankel, N. & Rauch-Krohnert, U. Front Immunol 13, 844701 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35359931
A Collaborative Approach for the Development and Application of Machine Learning Solutions for CMR-Based Cardiac Disease Classification. Huellebrand, M., Ivantsits, M., Tautz, L., Kelle, S. & Hennemuth, A. Front Cardiovasc Med 9, 829512 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360025
Editorial: Advances in the Prevention and Rehabilitation of Cardiovascular Diseases via Aerobic Exercise. Cao, R. Y., Kelle, S. & Yang, J. Front Cardiovasc Med 9, 858785 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360019
Identification of Specific Coronary Artery Disease Phenotypes Implicating Differential Pathophysiologies. Krohn, J. B., Nguyen, Y. N., Akhavanpoor, M., Erbel, C., Domschke, G., Linden, F., Kleber, M. E., Delgado, G., Marz, W., Katus, H. A. & Gleissner, C. A. Front Cardiovasc Med 9, 778206 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35355960
Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration. Nicolai, L., Leunig, A., Pekayvaz, K., Esefeld, M., Anjum, A., Rath, J., Riedlinger, E., Ehreiser, V., Mader, M., Eivers, L., Hoffknecht, M. L., Zhang, Z., Kugelmann, D., Rossaro, D., Escaig, R., Kaiser, R., Polewka, V., Titova, A., Petzold, T., Spiekermann, K. et al. Blood 140, 478-490 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35486845
Adult congenital heart disease patients undergoing mechanical circulatory support: Not all patients are the same. Csengeri, D., Bernhardt, A. M. & Sinning, C. J Heart Lung Transplant 41, 896-897 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35474250
Variability of biomarkers used for the classification of metabolic syndrome: A repeated measurements study. Ittermann, T., Dorr, M., Markus, M. R. P., Nauck, M., Jurgens, C., Schipf, S., Schmidt, C. O., Volzke, H. & Richter, A. Nutr Metab Cardiovasc Dis 32, 1693-1702 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35469729
Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study. Valerio, L., Mavromanoli, A. C., Barco, S., Abele, C., Becker, D., Bruch, L., Ewert, R., Faehling, M., Fistera, D., Gerhardt, F., Ghofrani, H. A., Grgic, A., Grunig, E., Halank, M., Held, M., Hobohm, L., Hoeper, M. M., Klok, F. A., Lankeit, M., Leuchte, H. H., Martin, N., Mayer, E., Meyer, F. J., Neurohr, C., Opitz, C., Schmidt, K. H., Seyfarth, H. J., Wachter, R., Wilkens, H., Wild, P. S., Konstantinides, S. V., Rosenkranz, S. & Investigators, F. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35484821
Establishing a robotic-assisted PCI program: experiences at a large tertiary referral center. Brunner, F. J., Waldeyer, C., Zengin-Sahm, E., Kondziella, C., Schrage, B., Clemmensen, P., Westermann, D., Blankenberg, S. & Seiffert, M. Heart Vessels (2022). https://www.ncbi.nlm.nih.gov/pubmed/35487996
Computational and experimental methods for classifying variants of unknown clinical significance. Spielmann, M. & Kircher, M. Cold Spring Harb Mol Case Stud 8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35483875
Neuroimmune cardiovascular interfaces control atherosclerosis. Mohanta, S. K., Peng, L., Li, Y., Lu, S., Sun, T., Carnevale, L., Perrotta, M., Ma, Z., Forstera, B., Stanic, K., Zhang, C., Zhang, X., Szczepaniak, P., Bianchini, M., Saeed, B. R., Carnevale, R., Hu, D., Nosalski, R., Pallante, F., Beer, M., Santovito, D., Erturk, A., Mettenleiter, T. C., Klupp, B. G., Megens, R. T. A., Steffens, S., Pelisek, J., Eckstein, H. H., Kleemann, R., Habenicht, L., Mallat, Z., Michel, J. B., Bernhagen, J., Dichgans, M., D'Agostino, G., Guzik, T. J., Olofsson, P. S., Yin, C., Weber, C., Lembo, G., Carnevale, D. & Habenicht, A. J. R. Nature 605, 152-159 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35477759
A machine learning algorithm for electrocardiographic fQRS quantification validated on multi-center data. Villa, A., Vandenberk, B., Kentta, T., Ingelaere, S., Huikuri, H. V., Zabel, M., Friede, T., Sticherling, C., Tuinenburg, A., Malik, M., Van Huffel, S., Willems, R. & Varon, C. Sci Rep 12, 6783 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35474073
Periprocedural myocardial injury according to optical characteristics of neointima and treatment modality of in-stent restenosis. Nano, N., Aytekin, A., Ndrepepa, G., Seguchi, M., Bresha, J., Alvarez Covarrubias, H. A., Nicol, P., Lenz, T., Lahu, S., Gewalt, S., Voll, F., Rheude, T., Wiebe, J., Schunkert, H., Kufner, S., Cassese, S., Joner, M., Kastrati, A. & Xhepa, E. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35476138
Effect of obesity on the associations of 25-hydroxyvitamin D with prevalent and incident distal sensorimotor polyneuropathy: population-based KORA F4/FF4 study. Maalmi, H., Herder, C., Huth, C., Rathmann, W., Bonhof, G. J., Heier, M., Koenig, W., Roden, M., Peters, A., Ziegler, D. & Thorand, B. Int J Obes (Lond) 46, 1366-1374 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35474356
Serial Assessment of Right Ventricular Deformation in Patients With Hypoplastic Left Heart Syndrome: A Cardiovascular Magnetic Resonance Feature Tracking Study. Kanngiesser, L. M., Freitag-Wolf, S., Boroni Grazioli, S., Gabbert, D. D., Hansen, J. H., Uebing, A. S. & Voges, I. J Am Heart Assoc 11, e025332 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35475354
Exome sequencing in individuals with cardiovascular laterality defects identifies potential candidate genes. Breuer, K., Riedhammer, K. M., Muller, N., Schaidinger, B., Dombrowsky, G., Dittrich, S., Zeidler, S., Bauer, U. M. M., Westphal, D. S., Meitinger, T., Dakal, T. C., Hitz, M. P., Breuer, J., Reutter, H., Hilger, A. C. & Hoefele, J. Eur J Hum Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35474353
Stent Optimization Using Optical Coherence Tomography and Its Prognostic Implications After Percutaneous Coronary Intervention. Rai, H., Harzer, F., Otsuka, T., Abdelwahed, Y. S., Antuna, P., Blachutzik, F., Koppara, T., Raber, L., Leistner, D. M., Alfonso, F., Nef, H., Seguchi, M., Aytekin, A., Xhepa, E., Kufner, S., Cassese, S., Laugwitz, K. L., Byrne, R. A., Kastrati, A. & Joner, M. J Am Heart Assoc 11, e02393 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35470682
Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI. Kaiser, R., Escaig, R., Kranich, J., Hoffknecht, M. L., Anjum, A., Polewka, V., Mader, M., Hu, W., Belz, L., Gold, C., Titova, A., Lorenz, M., Pekayvaz, K., Kaab, S., Gaertner, F., Stark, K., Brocker, T., Massberg, S. & Nicolai, L.Blood (2022). https://www.ncbi.nlm.nih.gov/pubmed/35472164
Towards lower radiation and contrast media dose CT angiography of the aorta by artificial intelligence-supported iterative reconstructions. Halfmann, M. C. & Emrich, T. Eur J Radiol 151, 110327 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35472648
Which patients with aortic stenosis should be referred to surgery rather than transcatheter aortic valve implantation? Windecker, S., Okuno, T., Unbehaun, A., Mack, M., Kapadia, S. & Falk, V. Eur Heart J(2022). https://www.ncbi.nlm.nih.gov/pubmed/35466382
Cardiac Cachexia Revisited: The Role of Wasting in Heart Failure. Valentova, M., Anker, S. D. & von Haehling, S. Cardiol Clin 40, 199-207 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35465894
[Cost-benefit analysis of new lipid-lowering agents]. Blaum, C., Arnold, N. & Waldeyer, C. Herz 47, 236-243 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35467096
Temporary mechanical circulatory support: Devices, outcomes, and future directions. Baran, D. A., Jaiswal, A., Hennig, F. & Potapov, E. J Heart Lung Transplant 41, 678-691 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35461760
Clinical Profile, Arrhythmias, and Adverse Cardiac Outcomes in Emery-Dreifuss Muscular Dystrophies: A Systematic Review of the Literature. Valenti, A. C., Albini, A., Imberti, J. F., Vitolo, M., Bonini, N., Lattanzi, G., Schnabel, R. B. & Boriani, G. Biology (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35453731
Treatment of Transthyretin Amyloid Cardiomyopathy: The Current Options, the Future, and the Challenges. Tschope, C. & Elsanhoury, A. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35456241
Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations. Spehlmann, M. E., Rangrez, A. Y., Dhotre, D. P., Schmiedel, N., Chavan, N., Bang, C., Muller, O. J., Shouche, Y. S., Franke, A., Frank, D. & Frey, N. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35453559
Therapeutic Alternatives in Diabetic Foot Patients without an Option for Revascularization: A Narrative Review. Ruemenapf, G., Morbach, S. & Sigl, M. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35456247
Validation of the 30-Year Framingham Risk Score in a German Population-Based Cohort. Rospleszcz, S., Starnecker, F., Linkohr, B., von Scheidt, M., Gieger, C., Schunkert, H., Peters, A. & DigiMed Bayern, C. Diagnostics (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35454012
Prediction of Successful Pharmacological Cardioversion in Acute Symptomatic Atrial Fibrillation: The Successful Intravenous Cardioversion for Atrial Fibrillation (SIC-AF) Score. Niederdockl, J. D., Simon, A., Buchtele, N., Schutz, N., Cacioppo, F., Oppenauer, J., Gupta, S., Lutnik, M., Schnaubelt, S., Spiel, A., Roth, D., Wimbauer, F., Fegers-Wustrow, I., Esefeld, K., Halle, M., Scharhag, J., Laschitz, T., Herkner, H., Domanovits, H. & Schwameis, M. J Pers Med 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35455660
Straightforward Analysis of Sulfated Glycosaminoglycans by MALDI-TOF Mass Spectrometry from Biological Samples. Kruger, L., Biskup, K., Karampelas, V., Ludwig, A., Kasper, A. S., Poller, W. C. & Blanchard, V. Biology (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35453706
Simultaneous Quantification and Pharmacokinetic Characterization of Doxapram and 2-Ketodoxapram in Porcine Plasma and Brain Tissue. Kraft, M., Foerster, K. I., Wiedmann, F., Sauter, M., Paasche, A., Blochberger, P. L., Yesilgoz, B., L'Hoste, Y., Frey, N., Haefeli, W. E., Burhenne, J. & Schmidt, C. Pharmaceutics 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35456597
The Structural and the Functional Aspects of Intercellular Communication in iPSC-Cardiomyocytes. Kiss, E., Fischer, C., Sauter, J. M., Sun, J. & Ullrich, N. D. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35457277
Introduction of Lazy Luna an automatic software-driven multilevel comparison of ventricular function quantification in cardiovascular magnetic resonance imaging. Hadler, T., Wetzl, J., Lange, S., Geppert, C., Fenski, M., Abazi, E., Groschel, J., Ammann, C., Wenson, F., Topper, A., Dauber, S. & Schulz-Menger, J. Sci Rep 12, 6629 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35459270
Pooled Analysis of Complications with Transvenous ICD Compared to Subcutaneous ICD in Patients with Catecholaminergic Polymorphic Ventricular Arrhythmia. Eckert, H., El-Battrawy, I., Veith, M., Roterberg, G., Kowitz, J., Lang, S., Zhou, X., Akin, I., Mugge, A. & Aweimer, A. J Pers Med 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35455651
Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay. Wallmeroth, D., Lackmann, J. W., Kueckelmann, S., Altmuller, J., Dieterich, C., Boehm, V. & Gehring, N. H. EMBO J, e109191 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451084
Definition, Classification and Diagnosis of Diabetes Mellitus. Schleicher, E., Gerdes, C., Petersmann, A., Muller-Wieland, D., Muller, U. A., Freckmann, G., Heinemann, L., Nauck, M. & Landgraf, R. Exp Clin Endocrinol Diabetes (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451038
Microbiota-derived tryptophan metabolites in vascular inflammation and cardiovascular disease. Paeslack, N., Mimmler, M., Becker, S., Gao, Z., Khuu, M. P., Mann, A., Malinarich, F., Regen, T. & Reinhardt, C. Amino Acids (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451695
Assessment of Myocardial Microstructure in a Murine Model of Obesity-Related Cardiac Dysfunction by Diffusion Tensor Magnetic Resonance Imaging at 7T. Lohr, D., Thiele, A., Stahnke, M., Braun, V., Smeir, E., Spranger, J., Brachs, S., Klopfleisch, R., Foryst-Ludwig, A., Schreiber, L. M., Kintscher, U. & Beyhoff, N. Front Cardiovasc Med 9, 839714 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35449873
Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK-STAT signaling in macrophages by perturbing lipid raft structures. Hammoud, M. K., Dietze, R., Pesek, J., Finkernagel, F., Unger, A., Bieringer, T., Nist, A., Stiewe, T., Bhagwat, A. M., Nockher, W. A., Reinartz, S., Muller-Brusselbach, S., Graumann, J. & Muller, R. Mol Oncol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451191
Background calcium influx in arrhythmia: lead actor or extra? Fakuade, F. E., Fauconnier, J. & Voigt, N. J Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35451079
Optical coherence tomography in coronary atherosclerosis assessment and intervention. Araki, M., Park, S. J., Dauerman, H. L., Uemura, S., Kim, J. S., Di Mario, C., Johnson, T. W., Guagliumi, G., Kastrati, A., Joner, M., Holm, N. R., Alfonso, F., Wijns, W., Adriaenssens, T., Nef, H., Rioufol, G., Amabile, N., Souteyrand, G., Meneveau, N., Gerbaud, E., Opolski, M. P., Gonzalo, N., Tearney, G. J., Bouma, B., Aguirre, A. D., Mintz, G. S., Stone, G. W., Bourantas, C. V., Raber, L., Gili, S., Mizuno, K., Kimura, S., Shinke, T., Hong, M. K., Jang, Y., Cho, J. M., Yan, B. P., Porto, I., Niccoli, G., Montone, R. A., Thondapu, V., Papafaklis, M. I., Michalis, L. K., Reynolds, H., Saw, J., Libby, P., Weisz, G., Iannaccone, M., Gori, T., Toutouzas, K., Yonetsu, T., Minami, Y., Takano, M., Raffel, O. C., Kurihara, O., Soeda, T., Sugiyama, T., Kim, H. O., Lee, T., Higuma, T., Nakajima, A., Yamamoto, E., Bryniarski, K. L., Di Vito, L., Vergallo, R., Fracassi, F., Russo, M., Seegers, L. M., McNulty, I., Park, S., Feldman, M., Escaned, J., Prati, F., Arbustini, E., Pinto, F. J., Waksman, R., Garcia-Garcia, H. M., Maehara, A., Ali, Z., Finn, A. V., Virmani, R., Kini, A. S., Daemen, J., Kume, T., Hibi, K., Tanaka, A., Akasaka, T., Kubo, T., Yasuda, S., Croce, K., Granada, J. F., Lerman, A., Prasad, A., Regar, E., Saito, Y., Sankardas, M. A., Subban, V., Weissman, N. J., Chen, Y., Yu, B., Nicholls, S. J., Barlis, P., West, N. E. J., Arbab-Zadeh, A., Ye, J. C., Dijkstra, J., Lee, H., Narula, J., Crea, F., Nakamura, S., Kakuta, T., Fujimoto, J., Fuster, V. & Jang, I. K. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35449407
Antiarrhythmic Effects of Vernakalant in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Short QT Syndrome Type 1. Xu, Q., Huang, X., Meng, Z., Li, Y., Zhong, R., Li, X., Cyganek, L., El-Battrawy, I., Akin, I., Zhou, X. & Lan, H. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35448088
Heart failure in the general population and impact of the 2021 European Society of Cardiology Heart Failure Guidelines. Wenzel, J. P., Nikorowitsch, J., Bei der Kellen, R., Magnussen, C., Bonin-Schnabel, R., Westermann, D., Twerenbold, R., Kirchhof, P., Blankenberg, S. & Schrage, B. ESC Heart Fail(2022). https://www.ncbi.nlm.nih.gov/pubmed/35445582
Quantitative Flow Ratio or Angiography for the Assessment of Non-culprit Lesions in Acute Coronary Syndromes: Protocol of the Randomized Trial QUOMODO. Ullrich, H., Olschewski, M., Belhadj, K. A., Munzel, T. & Gori, T. Front Cardiovasc Med 9, 815434 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35445090
Depressive symptoms predict the incidence of common chronic diseases in women and men in a representative community sample. Otten, D., Ernst, M., Werner, A. M., Tibubos, A. N., Reiner, I., Brahler, E., Wiltink, J., Michal, M., Nagler, M., Wild, P. S., Munzel, T., Konig, J., Lackner, K. J., Peiffer, N. & Beutel, M. E. Psychol Med, 1-9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35443907
Assessment of sex- and age-dependency of risk factors for intimal hyperplasia in heart transplant patients using the high resolution of optical coherence tomography. Orban, M., Dietl, M., Dischl, D., von Samson-Himmelstjerna, P., Neubarth-Mayer, J., Struven, A., Tengler, A., Jakob, A., Fischer, M., Rizas, K., Petzold, T., Orban, M., Braun, D., Hausleiter, J., Hagl, C., Haas, N. A., Mehilli, J., Pozza, R. D., Massberg, S. & Ulrich, S. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35447273
Ablation Lesion Assessment with MRI. Mont, L., Roca-Luque, I. & Althoff, T. F. Arrhythm Electrophysiol Rev11, e02 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35444808
Lipopolysaccharide Modifies Sodium Current Kinetics through ROS and PKC Signalling in Induced Pluripotent Stem-Derived Cardiomyocytes from Brugada Syndrome Patient. Liao, Z., Li, Y., Fan, X., Yang, Z., El-Battrawy, I., Zhou, X. & Akin, I. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35448095
Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis. Liang, G., Wang, S., Shao, J., Jin, Y., Xu, L., Yan, Y., Gunther, S., Wang, L. & Offermanns, S. Circ Res, 101161CIRCRESAHA121320694 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35443807
NMR Metabolomics Reveal Urine Markers of Microbiome Diversity and Identify Benzoate Metabolism as a Mediator between High Microbial Alpha Diversity and Metabolic Health. Hertel, J., Fassler, D., Heinken, A., Weiss, F. U., Ruhlemann, M., Bang, C., Franke, A., Budde, K., Henning, A. K., Petersmann, A., Volker, U., Volzke, H., Thiele, I., Grabe, H. J., Lerch, M. M., Nauck, M., Friedrich, N. & Frost, F. Metabolites 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35448495
Treatment of the Aortic Root in Acute Aortic Dissection Type A: Insights from the German Registry for Acute Aortic Dissection Type A (GERAADA) Registry. Kallenbach, K., Busch, C., Rylski, B., Dohle, D. S., Kruger, T., Holubec, T., Brickwedel, J., Poling, J., Noack, T., Hagl, C., Jawny, P., Boning, A., Chalabi, K., Karck, M. & Arif, R. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35441677
Effects of renin-angiotensin system inhibitor type and dosage on survival after transcatheter aortic valve implantation. Fischer-Rasokat, U., Bansch, C., Renker, M., Rolf, A., Charitos, E. I., Weferling, M., Liebetrau, C., Herrmann, E., Choi, Y. H., Hamm, C. W. & Kim, W. K. Eur Heart J Cardiovasc Pharmacother(2022). https://www.ncbi.nlm.nih.gov/pubmed/35441662
Movement therapy in lung transplantation candidates assisted by a lightweight wearable robot. Just, I. A., Fries, D., Loewe, S., Falk, V., Cesarovic, N., Kemper, D., Edelmann, F., Feuerstein, A., Haufe, F. L., Xiloyannis, M., Riener, R. & Schoenrath, F. Assist Technol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35438604
Frontiers in CardioVascular Biomedicine (FCVB) 2022 Budapest is on in person! The excellent programme proves that scientists won against COVID-19. Ferdinandy, P., Koller, Á., Weber, C., Wojta, J. & Waltenberger, J. Cardiovasc Res 118, e59-e61 (2022).
Frontiers of CardioVascular Biomedicine 2022 Budapest is on in person! The excellent program proves that scientists won against Covid-19. Ferdinandy, P., Koller, A., Weber, C., Wojta, J. & Waltenberger, J. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35438746
Ten-year patterns of stent thrombosis after percutaneous coronary intervention with new- versus early-generation drug-eluting stents: insights from the DECADE cooperation. Coughlan, J. J., Maeng, M., Raber, L., Brugaletta, S., Aytekin, A., Okkels Jensen, L., Bar, S., Ortega-Paz, L., Laugwitz, K. L., Madsen, M., Heg, D., Sabate, M., Kufner, S., Warnakula Olesen, K. K., Kastrati, A., Windecker, S. & Cassese, S. Rev Esp Cardiol (Engl Ed) (2022). https://www.ncbi.nlm.nih.gov/pubmed/35437213
Machine learning-based identification of risk-factor signatures for undiagnosed atrial fibrillation in primary prevention and post-stroke in clinical practice. Schnabel, R. B., Witt, H., Walker, J., Ludwig, M., Geelhoed, B., Kossack, N., Schild, M., Miller, R. & Kirchhof, P. Eur Heart J Qual Care Clin Outcomes (2022). https://www.ncbi.nlm.nih.gov/pubmed/35436783
Targeting Cell-Specific Molecular Mechanisms of Innate Immunity in Atherosclerosis. Sauter, M. & Langer, H. F. Front Physiol 13, 802990 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35432000
Prognostic Power of Pulmonary Arterial Compliance Is Boosted by a Hemodynamic Unloading Test With Glyceryl Trinitrate in Heart Failure Patients With Post-capillary Pulmonary Hypertension. Rieth, A. J., Grun, D., Zarogiannis, G., Kriechbaum, S. D., Wolter, S., Richter, M. J., Tello, K., Kruger, U., Mitrovic, V., Rosenkranz, S., Hamm, C. W. & Keller, T. Front Cardiovasc Med 9, 838898 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35433862
The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice. Nickel, L., Sunderhauf, A., Rawish, E., Stolting, I., Derer, S., Thorns, C., Matschl, U., Othman, A., Sina, C. & Raasch, W. Front Pharmacol 13, 815353 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35431918
Micro-dislodgement of a self-expanding transcatheter heart valve: Incidence, predictors, and outcomes. Kim, W. K., Renker, M., Dorr, O., Nef, H., Fischer-Rasokat, U., Choi, Y. H., Hamm, C. W. & Charitos, E. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35436560
Ruthenaelectro-catalyzed C-H acyloxylation for late-stage tyrosine and oligopeptide diversification. Hou, X., Kaplaneris, N., Yuan, B., Frey, J., Ohyama, T., Messinis, A. M. & Ackermann, L. Chem Sci 13, 3461-3467 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35432858
Cellular Chitchatting: Exploring the Role of Exosomes as Cardiovascular Risk Factors. Germena, G., Zelarayan, L. C. & Hinkel, R. Front Cell Dev Biol 10, 860005 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35433670
Transmitral Gradients Following Transcatheter Edge-to-Edge Repair: Are Mean Gradients Meaningful? Hahn, R. T. & Hausleiter, J. JACC Cardiovasc Interv (2022). https://www.ncbi.nlm.nih.gov/pubmed/35430172
Severe low-gradient aortic stenosis: impact of inadequate left ventricular responses to high afterload on diagnosis and therapeutic decision-making. Dandel, M. & Hetzer, R. Heart Fail Rev (2022). https://www.ncbi.nlm.nih.gov/pubmed/35430696
Proteome-wide quantitative RNA-interactome capture identifies phosphorylation sites with regulatory potential in RBM20. Vieira-Vieira, C. H., Dauksaite, V., Sporbert, A., Gotthardt, M. & Selbach, M. Mol Cell (2022). https://www.ncbi.nlm.nih.gov/pubmed/35427468
Clinical implications of low estimated protein intake in patients with heart failure. Streng, K. W., Hillege, H. L., Ter Maaten, J. M., van Veldhuisen, D. J., Dickstein, K., Ng, L. L., Samani, N. J., Metra, M., Ponikowski, P., Cleland, J. G., Anker, S. D., Romaine, S. P. R., Damman, K., van der Meer, P., Lang, C. C. & Voors, A. A. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35426256
Not the classical serendipity: does doxapram treat atrial fibrillation? Liutkute, A., Brundel, B. J. & Voigt, N. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35425974
Generation of heterozygous (MRli003-A-5) and homozygous (MRli003-A-6) voltage-sensing knock-in human iPSC lines by CRISPR/Cas9 editing of the AAVS1 locus. Zhang, F., Meier, A. B., Sinnecker, D., Engelhardt, S., Lipp, P., Laugwitz, K. L., Dorn, T. & Moretti, A. Stem Cell Res 61, 102785 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35421847
Symptom burden, psychosocial distress and palliative care needs in heart failure - A cross-sectional explorative pilot study. Strangl, F., Ischanow, E., Ullrich, A., Oechsle, K., Fluschnik, N., Magnussen, C., Knappe, D., Grahn, H., Blankenberg, S., Bokemeyer, C., Kirchhof, P. & Rybczynski, M. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420358
Surgical Restoration of Antero-Apical Left Ventricular Aneurysms: Cardiac Computed Tomography for Therapy Planning. Solowjowa, N., Nemchyna, O., Hrytsyna, Y., Meyer, A., Hennig, F., Falk, V. & Knosalla, C. Front Cardiovasc Med 9, 763073 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35419444
Four decades of experience of prosthetic valve endocarditis reflect a high variety of diverse pathogens. Oberbach, A., Schlichting, N., Hagl, C., Lehmann, S., Kullnick, Y., Friedrich, M., Kohl, U., Horn, F., Kumbhari, V., Loffler, B., Schmidt, F., Joskowiak, D., Born, F., Saha, S. & Bagaev, E. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420122
Prediction of disability-free survival in healthy older people. Neumann, J. T., Thao, L. T. P., Murray, A. M., Callander, E., Carr, P. R., Nelson, M. R., Wolfe, R., Woods, R. L., Reid, C. M., Shah, R. C., Newman, A. B., Williamson, J. D., Tonkin, A. M., McNeil, J. J. & investigators, A. Geroscience 44, 1641-1655 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420334
Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Melendez, E., Chondronasiou, D., Mosteiro, L., Martinez de Villarreal, J., Fernandez-Alfara, M., Lynch, C. J., Grimm, D., Real, F. X., Alcami, J., Climent, N., Pietrocola, F. & Serrano, M. Development 149 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35420133
Targeting the adipose tissue: heart crosstalk in pressure overload-induced heart failure. Tual-Chalot, S. & Stellos, K. Cardiovasc Res 118, 1854-1856 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35416985
The Polyscore of autonomic parameters predicts mortality and identifies low-risk individuals among diabetic survivors of acute myocardial infarction. Steger, A., Dommasch, M., Muller, A., Barthel, P., Sinnecker, D., Wieg, L., Hapfelmeier, A., Heidegger, H. H., Huster, K. M., Martens, E., Laugwitz, K. L., Schmidt, G. & Dirschinger, R. Sci Rep 12, 6069 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35414085
CARMA: what goes around, comes around for the heart. Juni, R. P. & Boon, R. A. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35416964
Patient related outcomes of mechanical lead extraction techniques (PROMET) study: A comparison of two professions. Akhtar, Z., Gallagher, M. M., Elbatran, A. I., Starck, C. T., Gonzalez, E., Al-Razzo, O., Mazzone, P., Delnoy, P. P., Breitenstein, A., Steffel, J., Eulert-Grehn, J., Lanmuller, P., Melillo, F., Marzi, A., Leung, L. W., Domenichini, G. & Sohal, M. Pacing Clin Electrophysiol 45, 658-665 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35417049
The Evolution of Complex Muscle Cell In Vitro Models to Study Pathomechanisms and Drug Development of Neuromuscular Disease. Zschuntzsch, J., Meyer, S., Shahriyari, M., Kummer, K., Schmidt, M., Kummer, S. & Tiburcy, M. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35406795
C-Reactive Protein to Albumin Ratio in Patients Undergoing Transcatheter Aortic Valve Replacement. Seoudy, H., Shamekhi, J., Voigtlander, L., Ludwig, S., Frank, J., Kujat, T., Bramlage, P., Al-Kassou, B., Sugiura, A., Rangrez, A. Y., Schofer, N., Puehler, T., Lutter, G., Seiffert, M., Nickenig, G., Conradi, L., Frey, N., Westermann, D., Sinning, J. M. & Frank, D. Mayo Clin Proc 97, 931-940 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35410750
A High-Protein and Low-Glycemic Formula Diet Improves Blood Pressure and Other Hemodynamic Parameters in High-Risk Individuals. Rohling, M., Kempf, K., Banzer, W., Braumann, K. M., Fuhrer-Sakel, D., Halle, M., McCarthy, D., Martin, S., Scholze, J., Toplak, H., Berg, A., Predel, H. G. & Acoorh Study, G. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35406053
Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation. Philippe, A., Kleinau, G., Gruner, J. J., Wu, S., Postpieszala, D., Speck, D., Heidecke, H., Dowell, S. J., Riemekasten, G., Hildebrand, P. W., Kamhieh-Milz, J., Catar, R., Szczepek, M., Dragun, D. & Scheerer, P. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35409344
Interdependence of Angiogenesis and Arteriogenesis in Development and Disease. le Noble, F. & Kupatt, C. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35409246
Elevation of cardiac biomarkers in stroke is associated with pathological findings on cardiac MRI-results of the HEart and BRain interfaces in Acute Stroke study. von Rennenberg, R., Herm, J., Krause, T., Hellwig, S., Stengl, H., Scheitz, J. F., Elgeti, T., Nagel, S. N., Endres, M., Haeusler, K. G. & Nolte, C. H. Int J Stroke, 17474930221095698 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35403503
Combining 3D-Printing and Electrospinning to Manufacture Biomimetic Heart Valve Leaflets. Freystetter, B., Grab, M., Grefen, L., Bischof, L., Isert, L., Mela, P., Bezuidenhout, D., Hagl, C. & Thierfelder, N. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35404357
Validity of a multidimensional comprehensive psychosocial screening instrument based on the ESC cardiovascular prevention guidelines - Evidence from the general and cardiovascular patient population. van den Houdt, S., Albus, C., Herrmann-Lingen, C., Widdershoven, J. & Kupper, N. J Psychosom Res 157, 110791 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35398675
TAVR - From inoperable to younger, lower-risk patients: A slippery slope? Unbehaun, A., Abdullah, M., Hooda, A., Gedela, M., Kempfert, J., Klein, C. & Tang, G. H. L. Prog Cardiovasc Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35398162
Rapid shear stress-dependent ENaC membrane insertion is mediated by the endothelial glycocalyx and the mineralocorticoid receptor. Cosgun, Z. C., Sternak, M., Fels, B., Bar, A., Kwiatkowski, G., Pacia, M. Z., Herrnbock, L., Lindemann, M., Stegbauer, J., Hoges, S., Chlopicki, S. & Kusche-Vihrog, K. Cell Mol Life Sci79, 235 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35397686
Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1. Bauer, A., Puglisi, M., Nagl, D., Schick, J. A., Werner, T., Klingl, A., El Andari, J., Hornung, V., Kessler, H., Gotz, M., Grimm, D. & Brack-Werner, R. Adv Sci (Weinh) 9, e2104979 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35398994
UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment. Bastian, L., Hartmann, A. M., Beder, T., Hanzelmann, S., Kassens, J., Bultmann, M., Hoeppner, M. P., Franzenburg, S., Wittig, M., Franke, A., Nagel, I., Spielmann, M., Reimer, N., Busch, H., Schwartz, S., Steffen, B., Viardot, A., Dohner, K., Kondakci, M., Wulf, G., Wendelin, K., Renzelmann, A., Kiani, A., Trautmann, H., Neumann, M., Gokbuget, N., Bruggemann, M. & Baldus, C. D. Leukemia 36, 1676-1680 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35397658
Matched comparison of 3 cerebral perfusion strategies in open zone-0 anastomosis for acute type A aortic dissection. Montagner, M., Kofler, M., Pitts, L., Heck, R., Buz, S., Kurz, S., Falk, V. & Kempfert, J. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35396839
Generation of two human iPSC lines, HMGUi003-A and MRIi028-A, carrying pathogenic biallelic variants in the PPCS gene. Iuso, A., Zhang, F., Rusha, E., Campbell, B., Dorn, T., Zanuttigh, E., Haas, D., Anikster, Y., Lederer, G., Pertek, A., Nteli, P., Laugwitz, K. L. & Moretti, A. Stem Cell Res 61, 102773 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35397396
Non-robotic minimally invasive mitral valve repair: a 20-year single-centre experience. Feirer, N., Kornyeva, A., Lang, M., Sideris, K., Voss, B., Krane, M., Lange, R. & Vitanova, K. Eur J Cardiothorac Surg(2022). https://www.ncbi.nlm.nih.gov/pubmed/35396837
Pediatric heart transplantation in infants and small children under 3 years of age: Single center experience - "Early and long-term results". Rosenthal, L. L., Ulrich, S. M., Zimmerling, L., Brenner, P., Muller, C., Michel, S., Horer, J., Netz, H., Haas, N. A. & Hagl, C. Int J Cardiol 356, 45-50 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395286
Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells. Peng, Y., Du, J., Gunther, S., Guo, X., Wang, S., Schneider, A., Zhu, L. & Braun, T. Redox Biol 52, 102309 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395625
Cardiac remodeling in patients with centrifugal left ventricular assist devices assessed by serial echocardiography. Mulzer, J., Krastev, H., Hoermandinger, C., Merke, N., Alhaloush, M., Schoenrath, F., Falk, V., Potapov, E. & Knierim, J. Echocardiography 39, 667-677 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35393693
Dysregulated diurnal cortisol patterns are associated with cardiovascular mortality: Findings from the KORA-F3 study. Karl, S., Johar, H., Ladwig, K. H., Peters, A. & Lederbogen, F. Psychoneuroendocrinology141, 105753 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395560
Galectin-3 inhibitors as novel antithrombotic drugs with almost no bleeding risk: wishful thinking or a realistic vision? Jakobs, K. & Rauch, U. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35393607
Transcatheter implantation of covered stents serving as extravascular conduits-Proof of a CT-based approach in three cases. Ewert, P., Eicken, A., Tanase, D., Georgiev, S., Will, A., Pankalla, C., Nagdyman, N., Meierhofer, C. & Horer, J. Catheter Cardiovasc Interv 99, 2054-2063 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35395135
Pharmacological Targeting of the CCL2/CCR2 Axis for Atheroprotection: A Meta-Analysis of Preclinical Studies. Zivkovic, L., Asare, Y., Bernhagen, J., Dichgans, M. & Georgakis, M. K. Arterioscler Thromb Vasc Biol 42, e131-e144 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35387476
Biomarker changes as surrogate endpoints in early-phase trials in heart failure with reduced ejection fraction. Savarese, G., Uijl, A., Ouwerkerk, W., Tromp, J., Anker, S. D., Dickstein, K., Hage, C., Lam, C. S. P., Lang, C. C., Metra, M., Ng, L. L., Orsini, N., Samani, N. J., van Veldhuisen, D. J., Cleland, J. G. F., Voors, A. A. & Lund, L. H. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35388650
Endocrine and molecular factors of increased female reproductive performance in the Dummerstorf high-fertility mouse line FL1. Ludwig, C. L. M., Bohleber, S., Rebl, A., Wirth, E. K., Venuto, M. T., Langhammer, M., Schweizer, U., Weitzel, J. M. & Michaelis, M. J Mol Endocrinol 69, 285-298 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35388794
Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation - A proof-of-concept study. Jebran, A. F., Tiburcy, M., Biermann, D., Balfanz, P., Didie, M., Karikkineth, B. C., Schondube, F., Kutschka, I. & Zimmermann, W. H. J Mol Cell Cardiol 168, 3-12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35390437
A Family and a Genome-Wide Polygenic Risk Score Are Independently Associated With Stroke in a Population-Based Study. Hammerle, M., Forer, L., Schonherr, S., Peters, A., Grallert, H., Kronenberg, F., Gieger, C. & Lamina, C. Stroke 53, 2331-2339 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35387493
Cardio-oncology imaging tools at the translational interface. Yaros, K., Eksi, B., Chandra, A., Agusala, K., Lehmann, L. H. & Zaha, V. G. J Mol Cell Cardiol 168, 24-32 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35385715
Attentive follow-up to counter alarmism. Twerenbold, R., Cavus, E. & Blankenberg, S. Eur Heart J 43, 1994 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35383357
ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. Rohlfing, A. K., Kolb, K., Sigle, M., Ziegler, M., Bild, A., Munzer, P., Sudmann, J., Dicenta, V., Harm, T., Manke, M. C., Geue, S., Kremser, M., Chatterjee, M., Liang, C., von Eysmondt, H., Dandekar, T., Heinzmann, D., Gunter, M., von Ungern-Sternberg, S., Buttcher, M., Castor, T., Mencl, S., Langhauser, F., Sies, K., Ashour, D., Beker, M. C., Lammerhofer, M., Autenrieth, S. E., Schaffer, T. E., Laufer, S., Szklanna, P., Maguire, P., Heikenwalder, M., Muller, K. A. L., Hermann, D. M., Kilic, E., Stumm, R., Ramos, G., Kleinschnitz, C., Borst, O., Langer, H. F., Rath, D. & Gawaz, M. Nat Commun 13, 1823 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35383158
New ESC/EACTS guideline recommendations for the treatment of secondary mitral regurgitation: reflections on the evidence. Frerker, C., Karam, N., Hahn, R. T., Thiele, H., Stone, G. W., Treede, H. & Hausleiter, J. Eur J Heart Fail 24, 746-749 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35385192
Adverse events and stroke prevention by interventional left atrial appendage occlusion in patients with low CHA2 DS2 -VASc score-results from the multicenter German LAARGE registry. Fastner, C., Brachmann, J., Lewalter, T., Zeymer, U., Sievert, H., Ledwoch, J., Geist, V., Hochadel, M., Schneider, S., Senges, J., Akin, I. & Ansari, U. Catheter Cardiovasc Interv 99, 2064-2070 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35384249
The everlasting challenge to identify deep vein thrombosis in both clinical practice and research. Behrendt, C. A., Twerenbold, R. & Blankenberg, S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35383353
Clinical implementation of RNA sequencing for Mendelian disease diagnostics. Yepez, V. A., Gusic, M., Kopajtich, R., Mertes, C., Smith, N. H., Alston, C. L., Ban, R., Beblo, S., Berutti, R., Blessing, H., Ciara, E., Distelmaier, F., Freisinger, P., Haberle, J., Hayflick, S. J., Hempel, M., Itkis, Y. S., Kishita, Y., Klopstock, T., Krylova, T. D., Lamperti, C., Lenz, D., Makowski, C., Mosegaard, S., Muller, M. F., Munoz-Pujol, G., Nadel, A., Ohtake, A., Okazaki, Y., Procopio, E., Schwarzmayr, T., Smet, J., Staufner, C., Stenton, S. L., Strom, T. M., Terrile, C., Tort, F., Van Coster, R., Vanlander, A., Wagner, M., Xu, M., Fang, F., Ghezzi, D., Mayr, J. A., Piekutowska-Abramczuk, D., Ribes, A., Rotig, A., Taylor, R. W., Wortmann, S. B., Murayama, K., Meitinger, T., Gagneur, J. & Prokisch, H. Genome Med 14, 38 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35379322
Effects of caloric restriction on the gut microbiome are linked with immune senescence. Sbierski-Kind, J., Grenkowitz, S., Schlickeiser, S., Sandforth, A., Friedrich, M., Kunkel, D., Glauben, R., Brachs, S., Mai, K., Thurmer, A., Radonic, A., Drechsel, O., Turnbaugh, P. J., Bisanz, J. E., Volk, H. D., Spranger, J. & von Schwartzenberg, R. J. Microbiome 10, 57 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35379337
Analytical interference of 33 different hemoglobin variants on HbA1c measurements comparing high-performance liquid chromatography with whole blood enzymatic assay: A multi-center study. Zechmeister, B., Erden, T., Kreutzig, B., Weber, M., Joly, P., Erdmann, J., Brockmann-Honig, C., Fischer, A. & Eidizadeh, A. Clin Chim Acta 531, 145-151 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35378091
Transcatheter aortic valve-in-valve implantation under cerebral protection in a patient with a deteriorated 19-mm rapid-deployment bioprosthetic valve. Van Praet, K. M., Nersesian, G., Kukucka, M., Heil, E., Kofler, M., Falk, V., Klein, C., Kempfert, J. & Unbehaun, A. Multimed Man Cardiothorac Surg 2022(2022). https://www.ncbi.nlm.nih.gov/pubmed/35377972
Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction. Cornean, A., Gierten, J., Welz, B., Mateo, J. L., Thumberger, T. & Wittbrodt, J. Elife 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35373735
Selective optogenetic control of Gq signaling using human Neuropsin. Wagdi, A., Malan, D., Sathyanarayanan, U., Beauchamp, J. S., Vogt, M., Zipf, D., Beiert, T., Mansuroglu, B., Dusend, V., Meininghaus, M., Schneider, L., Kalthof, B., Wiegert, J. S., Konig, G. M., Kostenis, E., Patejdl, R., Sasse, P. & Bruegmann, T. Nat Commun 13, 1765 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35365606
Computed tomography predictors of structural valve degeneration in patients undergoing transcatheter aortic valve implantation with balloon-expandable prostheses. Guglielmo, M., Fusini, L., Muratori, M., Tamborini, G., Mantegazza, V., Andreini, D., Annoni, A., Babbaro, M., Baggiano, A., Conte, E., Carriero, S., Formenti, A., Guaricci, A. I., Mancini, E., Mollace, R., Muscogiuri, G., Mushtaq, S., Ricci, F., Rossi, A., Scafuri, S., Alushi, B., Cau, C., Cau, R., Cesarano, M., Saba, L., Rabbat, M., Pepi, M. & Pontone, G. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35364711
Partial ring annuloplasty in the management of mitral annular calcification. Akansel, S., Kofler, M., Sundermann, S. H., Van Praet, K. M., Falk, V. & Kempfert, J. J Card Surg 37, 1749-1752 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35366352
Cardiac disease and prognosis associated with ventricular tachyarrhythmias in young adults and adults. Weidner, K., Behnes, M., Schupp, T., Hoppner, J., El-Battrawy, I., Ansari, U., Saleh, A., Taton, G., Reiser, L., Bollow, A., Reichelt, T., Ellguth, D., Engelke, N., Bertsch, T., Grosse Meininghaus, D., Hoffmann, U. & Akin, I. BMC Cardiovasc Disord 22, 136 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361107
High resolution optical mapping of cardiac electrophysiology in pre-clinical models. O'Shea, C., Winter, J., Kabir, S. N., O'Reilly, M., Wells, S. P., Baines, O., Sommerfeld, L. C., Correia, J., Lei, M., Kirchhof, P., Holmes, A. P., Fabritz, L., Rajpoot, K. & Pavlovic, D. Sci Data 9, 135 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361792
An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form. Menon, P. R., Staab, J., Gregus, A., Wirths, O. & Meyer, T. Cell Commun Signal 20, 42 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361236
Frailty, Guideline-Directed Medical Therapy, and Outcomes in HFrEF: From the GUIDE-IT Trial. Khan, M. S., Segar, M. W., Usman, M. S., Singh, S., Greene, S. J., Fonarow, G. C., Anker, S. D., Felker, G. M., Januzzi, J. L., Jr., Butler, J. & Pandey, A. JACC Heart Fail 10, 266-275 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361446
Comparison of American and European Guidelines for Primary Prevention of Cardiovascular Disease: JACC Guideline Comparison. Fegers-Wustrow, I., Gianos, E., Halle, M. & Yang, E. J Am Coll Cardiol 79, 1304-1313 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35361353
Surgical treatment of tricuspid valve dysplasia in children. Cleuziou, J., Pringsheim, M., Stroh, A., Burri, M., Lange, R. & Horer, J. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35362523
Synthetic Extracellular Volume in Cardiac Magnetic Resonance Without Blood Sampling: a Reliable Tool to Replace Conventional Extracellular Volume. Chen, W., Doeblin, P., Al-Tabatabaee, S., Klingel, K., Tanacli, R., Jakob Weiss, K., Stehning, C., Patel, A. R., Pieske, B., Zou, J. & Kelle, S. Circ Cardiovasc Imaging 15, e013745 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35360924
Impact of machine-learning-based coronary computed tomography angiography-derived fractional flow reserve on decision-making in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. Brandt, V., Schoepf, U. J., Aquino, G. J., Bekeredjian, R., Varga-Szemes, A., Emrich, T., Bayer, R. R., 2nd, Schwarz, F., Kroencke, T. J., Tesche, C. & Decker, J. A. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35359166
Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Malacarne, P. F., Ratiu, C., Gajos-Draus, A., Muller, N., Lopez, M., Pfluger-Muller, B., Ding, X., Warwick, T., Oo, J., Siragusa, M., Angioni, C., Gunther, S., Weigert, A., Geisslinger, G., Lutjohann, D., Schunck, W. H., Fleming, I., Brandes, R. P. & Rezende, F. Hypertension 79, 1216-1226 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35354305
Serum starvation induces sexual dimorphisms in secreted proteins of human umbilical vein endothelial cells (HUVECs) from twin pairs. Lorenz, M., Witt, E., Volker, U., Stangl, K., Stangl, V. & Hammer, E. Proteomics, e2100168 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35357760
Comparison of transient and permanent LAD ligation in mice using 18F-FDG PET imaging. Fischer, M., Weinberger, T., Messerer, D., Zacherl, M. J., Schulz, C., Massberg, S., Bartenstein, P., Lehner, S., Boening, G. & Todica, A. Ann Nucl Med 36, 533-543 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35355159
Mai
Paper of the Month
MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice. Peters, L. J. F., Baaten, C., Maas, S. L., Lu, C., Nagy, M., Jooss, N. J., Bidzhekov, K., Santovito, D., Moreno-Andres, D., Jankowski, J., Biessen, E. A. L., Doring, Y., Heemskerk, J. W. M., Weber, C., Kuijpers, M. J. E. & van der Vorst, E. P. C. Biomedicines 10(2022). https://www.ncbi.nlm.nih.gov/pubmed/35625720
Dual-Positive MPO- and PR3-ANCA-Associated Vasculitis Following SARS-CoV-2 mRNA Booster Vaccination: A Case Report and Systematic Review. Baier, E., Olgemoller, U., Biggemann, L., Buck, C. & Tampe, B. Vaccines (Basel) 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35632410
Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart Repair. Tiburcy, M., Meyer, T., Satin, P. L. & Zimmermann, W. H. Methods Mol Biol 2485, 213-225 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35618908
Human-Engineered Atrial Tissue for Studying Atrial Fibrillation. Krause, J., Lemme, M., Mannhardt, I., Eder, A., Ulmer, B., Eschenhagen, T. & Stenzig, J. Methods Mol Biol 2485, 159-173 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35618905
Lung cell toxicity of co-exposure to airborne particulate matter and extremely low-frequency magnetic field. Panjali, Z., Abdolmaleki, P., Hajipour-Verdom, B., Hahad, O. & Zendehdel, R. Xenobiotica52, 370-379 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35608272
Incidence and Outcome of Patients with Cardiogenic Shock and Detection of Herpes Simplex Virus in the Lower Respiratory Tract. Scherer, C., Lusebrink, E., Binzenhofer, L., Stocker, T. J., Kupka, D., Chung, H. P., Stambollxhiu, E., Alemic, A., Kellnar, A., Deseive, S., Stark, K., Petzold, T., Hagl, C., Hausleiter, J., Massberg, S. & Orban, M. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35566477
Structural Analysis of Mitochondrial Dynamics-From Cardiomyocytes to Osteoblasts: A Critical Review. Mendelsohn, D. H., Schnabel, K., Mamilos, A., Sossalla, S., Pabel, S., Duerr, G. D., Keller, K., Schmitt, V. H., Barsch, F., Walter, N., Wong, R. M. Y., El Khassawna, T., Niedermair, T., Alt, V., Rupp, M. & Brochhausen, C. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35562962
Artificial Intelligence Enabled Fully Automated CMR Function Quantification for Optimized Risk Stratification in Patients Undergoing Transcatheter Aortic Valve Replacement. Evertz, R., Lange, T., Backhaus, S. J., Schulz, A., Beuthner, B. E., Topci, R., Toischer, K., Puls, M., Kowallick, J. T., Hasenfuss, G. & Schuster, A. J Interv Cardiol 2022, 1368878 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35539443
Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Taub, M. A., Conomos, M. P., Keener, R., Iyer, K. R., Weinstock, J. S., Yanek, L. R., Lane, J., Miller-Fleming, T. W., Brody, J. A., Raffield, L. M., McHugh, C. P., Jain, D., Gogarten, S. M., Laurie, C. A., Keramati, A., Arvanitis, M., Smith, A. V., Heavner, B., Barwick, L., Becker, L. C. et al. Cell Genom 2 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35530816
Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting. Speck, D., Kleinau, G., Szczepek, M., Kwiatkowski, D., Catar, R., Philippe, A. & Scheerer, P. Front Endocrinol (Lausanne) 13, 880002 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35518926
Hemodynamic Changes During Physiological and Pharmacological Stress Testing in Patients With Heart Failure: A Systematic Review and Meta-Analysis. Bingel, A., Messroghli, D., Weimar, A., Runte, K., Salcher-Konrad, M., Kelle, S., Pieske, B., Berger, F., Kuehne, T., Goubergrits, L., Fuerstenau, D. & Kelm, M. Front Cardiovasc Med 9, 718114 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35514442
Magnetic resonance imaging-based diagnosis of aortitis preceding development of a thoracic aneurysm in a patient with giant cell arteritis: a case report. Lutter, G., Puehler, T., Rocken, C. & Both, M. Eur Heart J Case Rep 6, ytac152 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35505863
CILP1 as a biomarker for right ventricular dysfunction in patients with ischemic cardiomyopathy. Keranov, S., Jafari, L., Haen, S., Vietheer, J., Kriechbaum, S., Dorr, O., Liebetrau, C., Troidl, C., Rutsatz, W., Rieth, A., Hamm, C. W., Nef, H., Rolf, A. & Keller, T. Pulm Circ 12, e12062 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35506075
Transcatheter Caval Valve Implantation for Tricuspid Regurgitation After Single Leaflet Device Attachment. Rroku, A., Barbieri, F., Landmesser, U., Skurk, C., Kasner, M. & Reinthaler, M. JACC Case Rep4, 481-485 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35493801
Sex disparities in patients with suspected COVID-19 presenting at an emergency department in Switzerland. Arslani, K., Eken, C., Tschudin-Sutter, S., Gebhard, C. E., Zellweger, N., Bassetti, S., Bingisser, R., Lampart, M., Osswald, S., Kuster, G. M., Twerenbold, R. & investigators, C. Swiss Med Wkly 152 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35633632
Effect of Thrombin on the Metabolism and Function of Murine Macrophages. Ukan, U., Delgado Lagos, F., Kempf, S., Gunther, S., Siragusa, M., Fisslthaler, B. & Fleming, I. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35626753
Structured, Harmonized, and Interoperable Integration of Clinical Routine Data to Compute Heart Failure Risk Scores. Sommer, K. K., Amr, A., Bavendiek, U., Beierle, F., Brunecker, P., Dathe, H., Eils, J., Ertl, M., Fette, G., Gietzelt, M., Heidecker, B., Hellenkamp, K., Heuschmann, P., Hoos, J. D. E., Kesztyus, T., Kerwagen, F., Kindermann, A., Krefting, D., Landmesser, U., Marschollek, M. et al. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35629415
Atherosclerosis and Its Impact on the Outcomes of Patients with Deep Venous Thrombosis. Keller, K., Prochaska, J. H., Coldewey, M., Gobel, S., Schmitt, V. H., Hahad, O., Ullmann, A., Nagler, M., Lamparter, H., Espinola-Klein, C., Munzel, T. & Wild, P. S. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35629401
Pulmonary Artery Pressure-Guided Telemonitoring Reduced Pulmonary Artery Pressure but Did Not Result in Higher Doses of Guideline-Directed Medical Therapy-Observations from an Advanced Elderly German Heart Failure Cohort. Herrmann, E. J., Raghavan, B., Eissing, N., Fichtlscherer, S., Hamm, C. W. & Assmus, B. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35629432
Metabolomic Profiling in Patients with Heart Failure and Exercise Intolerance: Kynurenine as a Potential Biomarker. Bekfani, T., Bekhite, M., Neugebauer, S., Derlien, S., Hamadanchi, A., Nisser, J., Hilse, M. S., Haase, D., Kretzschmar, T., Wu, M. F., Lichtenauer, M., Kiehntopf, M., von Haehling, S., Schlattmann, P., Lehmann, G., Franz, M., Mobius-Winkler, S. & Schulze, C. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35626711
Right Antero-Lateral Mini-Thoracotomy Surgical Aortic Valve Replacement. Van Praet, K. M., Nersesian, G., Kofler, M., Sundermann, S. H., Unbehaun, A., Falk, V. & Kempfert, J. Surg Technol Int 41(2022). https://www.ncbi.nlm.nih.gov/pubmed/35623038
David Procedure as Valve-Sparing Root Replacement. Pitts, L., Van Praet, K. M., Montagner, M., Kofler, M., Falk, V. & Kempfert, J. Surg Technol Int 41 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35623037
Rac1 regulates lipid droplets formation, nanomechanical, and nanostructural changes induced by TNF in vascular endothelium in the isolated murine aorta. Pacia, M. Z., Chorazy, N., Sternak, M., Fels, B., Pacia, M., Kepczynski, M., Kusche-Vihrog, K. & Chlopicki, S. Cell Mol Life Sci 79, 317 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35622139
The Relationship Between Vitamin D and Postoperative Atrial Fibrillation: A Prospective Cohort Study. Ohlrogge, A. H., Brederecke, J., Ojeda, F. M., Pecha, S., Borschel, C. S., Conradi, L., Rimkus, V., Blankenberg, S., Zeller, T. & Schnabel, R. B. Front Nutr 9, 851005 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35619954
Clinical utility of inflammatory biomarkers in COVID-19 in direct comparison to other respiratory infections-A prospective cohort study. Lampart, M., Zellweger, N., Bassetti, S., Tschudin-Sutter, S., Rentsch, K. M., Siegemund, M., Bingisser, R., Osswald, S., Kuster, G. M. & Twerenbold, R. PLoS One 17, e0269005 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35622838
Understanding the Role of SERCA2a Microdomain Remodeling in Heart Failure Induced by Obesity and Type 2 Diabetes. Lai, P., Nikolaev, V. O. & De Jong, K. A. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35621874
Generalizability of the EAST-AFNET 4 Trial: Assessing Outcomes of Early Rhythm-Control Therapy in Patients With Atrial Fibrillation. Dickow, J., Kirchhof, P., Van Houten, H. K., Sangaralingham, L. R., Dinshaw, L. H. W., Friedman, P. A., Packer, D. L., Noseworthy, P. A. & Yao, X. J Am Heart Assoc 11, e024214 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35621202
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity. Batlle, D., Monteil, V., Garreta, E., Hassler, L., Wysocki, J., Chandar, V., Schwartz, R. E., Mirazimi, A., Montserrat, N., Bader, M. & Penninger, J. M. Cell 185, 1837-1839 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35623327
Remote control of the heart and beyond. Zimmermann, W. H. Science 376, 917-918 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35617399
Stand-alone Focal Impulse and Rotor Modulation (FIRM) ablation versus second-generation cryoballoon pulmonary vein isolation for paroxysmal atrial fibrillation. Tilz, R. R., Yalin, K., Lyan, E., Heeger, C. H., Schluter, M., Fink, T., Sciacca, V., Liosis, S., Kuck, K. H., Popescu, S. S., Mortensen, K., Meyer-Saraei, R., Eitel, C. & Vogler, J. J Cardiovasc Electrophysiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35615939
Hidden Agenda - The Involvement of Endoplasmic Reticulum Stress and Unfolded Protein Response in Inflammation-Induced Muscle Wasting. Kny, M. & Fielitz, J. Front Immunol 13, 878755 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35615361
Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction. Kleist, C. J., Choe, C. U., Atzler, D., Schonhoff, M., Boger, R., Schwedhelm, E. & Wicha, S. G. Amino Acids 54, 889-896 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35618975
Gender Differences in Takotsubo Syndrome. Arcari, L., Nunez Gil, I. J., Stiermaier, T., El-Battrawy, I., Guerra, F., Novo, G., Musumeci, B., Cacciotti, L., Mariano, E., Caldarola, P., Parisi, G., Montisci, R., Vitale, E., Sclafani, M., Volpe, M., Corbi-Pasqual, M., Martinez-Selles, M., Almendro-Delia, M., Sionis, A., Uribarri, A. et al. J Am Coll Cardiol 79, 2085-2093 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35618345
Implementation of a Clinical Trial Recruitment Support System Based on Fast Healthcare Interoperability Resources (FHIR) in a Cardiology Department. Scherer, C., Endres, S., Orban, M., Kaab, S., Massberg, S., Winter, A. & Lobe, M. Stud Health Technol Inform 294, 440-444 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35612118
Patient Characteristics, Procedural Characteristics, and Outcomes in Patients Having Lead Extraction in a High-Volume Center. O'Connor, M., Schmidt, P., Knoll, K., Schaarschmidt, C., Bock, M., Bahlke, F., Georgi, M., Frohlich, R., Sonne, C., Kottmaier, M., Reents, T., Bourier, F., Hessling, G., Deisenhofer, I., Kolb, C. & Lennerz, C. Am J Cardiol 176, 51-57 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35613955
The long non-coding RNA MEG8 induces an endothelial barrier through regulation of microRNA-370 and -494 processing. Kremer, V., Stanicek, L., van Ingen, E., Bink, D. I., Hilderink, S., Tijsen, A. J., Wittig, I., Magdefessel, L., Nossent, A. Y. & Boon, R. A. J Cell Sci 135 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35611612
Serotonin limits generation of chromaffin cells during adrenal organ development. Kameneva, P., Melnikova, V. I., Kastriti, M. E., Kurtova, A., Kryukov, E., Murtazina, A., Faure, L., Poverennaya, I., Artemov, A. V., Kalinina, T. S., Kudryashov, N. V., Bader, M., Skoda, J., Chlapek, P., Curylova, L., Sourada, L., Neradil, J., Tesarova, M., Pasqualetti, M., Gaspar, P. et al. Nat Commun 13, 2901 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35614045
Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors. Bayo Jimenez, M. T., Frenis, K., Hahad, O., Steven, S., Cohen, G., Cuadrado, A., Munzel, T. & Daiber, A. Free Radic Biol Med 187, 72-91 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35613665
Virtual reality in cardiac interventions-New tools or new toys? Sundermann, S. H., Hennemuth, A. & Kempfert, J. J Card Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35610730
Safety and performance of a novel cerebral embolic protection device for transcatheter aortic valve implantation: the PROTEMBO C Trial. Jagielak, D., Targonski, R., Frerker, C., Abdel-Wahab, M., Wilde, J., Werner, N., Lauterbach, M., Leick, J., Grygier, M., Misterski, M., Erglis, A., Narbute, I., Witkowski, A. R., Adam, M., Frank, D., Gatto, F., Schmidt, T. & Lansky, A. J. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/35608032
Insulin-Like Growth Factor, Inflammation, and MRI Markers of Alzheimer's Disease in Predominantly Middle-Aged Adults. Wittfeld, K., Raman, M. R., Conner, S. C., Aslam, A., Teumer, A., Nauck, M., Hosten, N., Habes, M., DeCarli, C., Vasan, R. S., Beiser, A. S., Himali, J. J., Seshadri, S., Grabe, H. J. & Satizabal, C. L. J Alzheimers Dis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35599493
Real-Time Electrocardiogram Monitoring during Treadmill Training in Mice. Tomsits, P., Sharma Chivukula, A., Raj Chataut, K., Simahendra, A., Weckbach, L. T., Brunner, S. & Clauss, S. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35604201
Drug-coated balloons in below-the-knee arteries. Stoll, F., Uslu, R., Blessing, E., Frey, N., Katus, H. A., Erbel, C., Heilmeier, B. & Muller, O. J. Vasa (2022). https://www.ncbi.nlm.nih.gov/pubmed/35604329
Lived experiences of patients implanted with left ventricular assist devices. Inyom, C., Haese, T., Schoenrath, F., Potapov, E. & Knierim, J. Heart Lung 55, 155-161 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35605356
Inflammatory Mediators in Atherosclerotic Vascular Remodeling. Evans, B. R., Yerly, A., van der Vorst, E. P. C., Baumgartner, I., Bernhard, S. M., Schindewolf, M. & Doring, Y. Front Cardiovasc Med 9, 868934 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35600479
Awareness of sex and gender dimensions among physicians: the European federation of internal medicine assessment of gender differences in Europe (EFIM-IMAGINE) survey. Biskup, E., Marra, A. M., Ambrosino, I., Barbagelata, E., Basili, S., de Graaf, J., Gonzalvez-Gasch, A., Kaaja, R., Karlafti, E., Lotan, D., Kautzky-Willer, A., Perticone, M., Politi, C., Schenck-Gustafsson, K., Vilas-Boas, A., Roeters van Lennep, J., Gans, E. A., Regitz-Zagrosek, V., Pilote, L., Proietti, M. et al. Intern Emerg Med 17, 1395-1404 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35604515
Outcomes with empagliflozin in heart failure with preserved ejection fraction using DELIVER-like endpoint definitions. Anker, S. D., Siddiqi, T. J., Filippatos, G., Zannad, F., Ferreira, J. P., Pocock, S. J., Brueckmann, M., Zeller, C., Packer, M. & Butler, J. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35604680
Maternal socioeconomic and lifestyle factors and life dissatisfaction associated with a small for gestational age infant. The Survey of Neonates in Pomerania (SNiP). Pierdant, G., Ittermann, T., Freyer-Adam, J., Siewert-Markus, U., Grabe, H. J., Dorr, M., Heckmann, M., Zygmunt, M., Lange, A. E. & Markus, M. R. P. Arch Gynecol Obstet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35599250
Infective endocarditis due to Staphylococcus aureus in adults with congenital heart disease: The next challenge. Tutarel, O. Int J Cardiol 362, 74-75 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35597497
Distinct pathophysiological pathways in women and men with heart failure. Ravera, A., Santema, B. T., de Boer, R. A., Anker, S. D., Samani, N. J., Lang, C. C., Ng, L., Cleland, J. G. F., Dickstein, K., Lam, C. S. P., Van Spall, H. G. C., Filippatos, G., van Veldhuisen, D. J., Metra, M., Voors, A. A. & Sama, I. E. Eur J Heart Fail(2022). https://www.ncbi.nlm.nih.gov/pubmed/35596674
Intranasal application of adeno-associated viruses: a systematic review. Gadenstaetter, A. J., Schmutzler, L., Grimm, D. & Landegger, L. D. Transl Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35597541
Resting heart rate and incident atrial fibrillation: A stratified Mendelian randomization in the AFGen consortium. Siland, J. E., Geelhoed, B., Roselli, C., Wang, B., Lin, H. J., Weiss, S., Trompet, S., van den Berg, M. E., Soliman, E. Z., Chen, L. Y., Ford, I., Jukema, J. W., Macfarlane, P. W., Kornej, J., Lin, H., Lunetta, K. L., Kavousi, M., Kors, J. A., Ikram, M. A., Guo, X. et al. PLoS One 17, e0268768 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35594314
Midterm Follow-up of the Transatrial-to-Left Ventricle Cannulation for Acute Type A Dissection. Puehler, T., Friedrich, C., Lutter, G., Frank, D., Saad, M., Seoudy, H., Salem, M., Schoettler, J., Cremer, J. & Haneya, A. Ann Thorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35595088
Association of early electrical changes with cardiovascular outcomes in immune checkpoint inhibitor myocarditis. Power, J. R., Alexandre, J., Choudhary, A., Ozbay, B., Hayek, S. S., Asnani, A., Tamura, Y., Aras, M., Cautela, J., Thuny, F., Gilstrap, L., Arangalage, D., Ewer, S., Huang, S., Deswal, A., Palaskas, N. L., Finke, D., Lehmann, L. H., Ederhy, S., Moslehi, J. et al. Arch Cardiovasc Dis 115, 315-330 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35595646
Empagliflozin in patients post myocardial infarction rationale and design of the EMPACT-MI trial. Harrington, J., Udell, J. A., Jones, W. S., Anker, S. D., Bhatt, D. L., Petrie, M. C., Vedin, O., Sumin, M., Zwiener, I., Hernandez, A. F. & Butler, J. Am Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35595091
Inflammation and remodeling pathways and risk of cardiovascular events in patients with ischemic heart failure and reduced ejection fraction. Girerd, N., Cleland, J., Anker, S. D., Byra, W., Lam, C. S. P., Lapolice, D., Mehra, M. R., van Veldhuisen, D. J., Bresso, E., Lamiral, Z., Greenberg, B. & Zannad, F. Sci Rep 12, 8574 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35595781
Sodium Glucose Cotransporter-2 Inhibition for Acute Myocardial Infarction: JACC Review Topic of the Week. Udell, J. A., Jones, W. S., Petrie, M. C., Harrington, J., Anker, S. D., Bhatt, D. L., Hernandez, A. F. & Butler, J. J Am Coll Cardiol 79, 2058-2068 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35589167
The erythropoietin-derived peptide ARA 284 reduces tissue wasting and improves survival in a rat model of cancer cachexia. Palus, S., Elkina, Y., Braun, T., von Haehling, S., Dohner, W., Anker, S. D., Cerami, A., Brines, M. & Springer, J. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/35586884
Clinical Features and Natural History of Preadolescent Nonsyndromic Hypertrophic Cardiomyopathy. Norrish, G., Cleary, A., Field, E., Cervi, E., Boleti, O., Ziolkowska, L., Olivotto, I., Khraiche, D., Limongelli, G., Anastasakis, A., Weintraub, R., Biagini, E., Ragni, L., Prendiville, T., Duignan, S., McLeod, K., Ilina, M., Fernandez, A., Marrone, C., Bokenkamp, R. et al. J Am Coll Cardiol 79, 1986-1997 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35589160
Characterization of critically ill patients with septic shock and sepsis-associated cardiomyopathy using cardiovascular MRI. Muehlberg, F., Blaszczyk, E., Will, K., Wilczek, S., Brederlau, J. & Schulz-Menger, J. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35587684
Obesity and Its Impact on Adverse In-Hospital Outcomes in Hospitalized Patients With COVID-19. Keller, K., Sagoschen, I., Schmitt, V. H., Sivanathan, V., Espinola-Klein, C., Lavie, C. J., Munzel, T. & Hobohm, L. Front Endocrinol (Lausanne) 13, 876028 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35586628
Adjunctive Left Atrial Posterior Wall Isolation in Treating Atrial Fibrillation: Insight From a Large Secondary Analysis. Jiang, X., Liao, J., Ling, Z., Meyer, C., Sommer, P., Futyma, P., Martinek, M., Schratter, A., Acou, W. J., Wang, J., Zhu, L., Kiuchi, M. G., Purerfellner, H., Schmidt, B., Chun, J. K. R., Yin, Y. & Chen, S. JACC Clin Electrophysiol 8, 605-618 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35589173
Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening. Flitsch, L. J., Borner, K., Stullein, C., Ziegler, S., Sonntag-Buck, V., Wiedtke, E., Semkova, V., Au Yeung, S. W. C., Schlee, J., Hajo, M., Mathews, M., Ludwig, B. S., Kossatz, S., Kessler, H., Grimm, D. & Brustle, O. Sci Rep 12, 8356 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35589936
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state. Bosmans, L. A., van Tiel, C. M., Aarts, S., Willemsen, L., Baardman, J., van Os, B. W., den Toom, M., Beckers, L., Ahern, D. J., Levels, J. H. M., Jongejan, A., Moerland, P. D., Verberk, S. G. S., van den Bossche, J., de Winther, M., Weber, C., Atzler, D., Monaco, C., Gerdes, N., Shami, A. et al. Cardiovasc Res(2022). https://www.ncbi.nlm.nih.gov/pubmed/35587037
Impact of cardiac amyloidosis on outcomes of patients hospitalized with heart failure. Sebastian, G., Lukas, H., Alexander, D., Tommaso, G., Thomas, M., Rapezzi, C., Philip, W. & Karsten, K. Eur J Intern Med(2022). https://www.ncbi.nlm.nih.gov/pubmed/35584975
Impact of cardiac amyloidosis on outcomes of patients hospitalized with heart failure. Gobel, S., Hobohm, L., Desuki, A., Gori, T., Munzel, T., Claudio, R., Wenzel, P. & Keller, K. Eur J Intern Med 102, 88-96 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35584975
New remote cerebral microbleeds in acute ischemic stroke: an analysis of the randomized, placebo-controlled WAKE-UP trial. Braemswig, T. B., Vynckier, J., Jensen, M., Boutitie, F., Galinovic, I., Simonsen, C. Z., Cheng, B., Cho, T. H., Scheitz, J. F., Fiehler, J., Puig, J., Thijs, V., Fiebach, J. B., Muir, K. W., Nighoghossian, N., Ebinger, M., Pedraza, S., Thomalla, G., Gerloff, C., Endres, M. et al. J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35585334
Epicutaneous application of Imiquimod to model psoriasis-like skin disease induces water-saving aestivation motifs and vascular inflammation. Wild, J., Ringen, J., Bieler, T., Knopp, T., Lagrange, J., Molitor, M., Sies, K., Kropp, A., Keller, K., Daiber, A., Munzel, T., Rauh, M., Waisman, A., Wenzel, P., Titze, J. & Karbach, S. J Invest Dermatol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35580696
The interplay between genetic variation and gene expression of the glucocorticoid receptor gene NR3C1 and blood cortisol levels on verbal memory and hippocampal volumes. Van der Auwera, S., Klinger-Konig, J., Wittfeld, K., Terock, J., Hannemann, A., Bulow, R., Nauck, M., Volker, U., Volzke, H. & Grabe, H. J. Eur Arch Psychiatry Clin Neurosci (2022). https://www.ncbi.nlm.nih.gov/pubmed/35579746
The need for increased pragmatism in cardiovascular clinical trials. Usman, M. S., Van Spall, H. G. C., Greene, S. J., Pandey, A., McGuire, D. K., Ali, Z. A., Mentz, R. J., Fonarow, G. C., Spertus, J. A., Anker, S. D., Butler, J., James, S. K. & Khan, M. S. Nat Rev Cardiol, 1-14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35581337
Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes. Kloth, B., Mearini, G., Weinberger, F., Stenzig, J., Geertz, B., Starbatty, J., Lindner, D., Schumacher, U., Reichenspurner, H., Eschenhagen, T. & Hirt, M. N. Sci Rep 12, 8193 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35581325
Carotid ultrasonography improves residual risk stratification in guidelines-defined high cardiovascular risk patients. Georgiopoulos, G., Mavraganis, G., Delialis, D., Georgiou, S., Aivalioti, E., Patras, R., Petropoulos, I., Dimopoulou, M. A., Angelidakis, L., Sianis, A., Bampatsias, D., Dimoula, A., Maneta, E., Kosmopoulos, M., Vardavas, C., Stellos, K. & Stamatelopoulos, K. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35580589
Head-to-head comparison between recommendations by the ESC and ACC/AHA/HFSA heart failure guidelines. Bayes-Genis, A., Aimo, A., Metra, M., Anker, S., Seferovic, P., Rapezzi, C., Castiglione, V., Nunez, J., Emdin, M., Rosano, G. & Coats, A. J. S. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35579428
Increased Concentrations of Circulating Interleukins following Non-Invasive Vagus Nerve Stimulation: Results from a Randomized, Sham-Controlled, Crossover Study in Healthy Subjects. Veiz, E., Kieslich, S. K., Czesnik, D., Herrmann-Lingen, C., Meyer, T. & Staab, J. Neuroimmunomodulation, 1-10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35576915
The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen. Spada, S., Luke, B. & Danckwardt, S. Front Genet 13, 854907 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35571036
Compensatory Upregulation of Anti-Beta-Adrenergic Receptor Antibody Levels Might Prevent Heart Failure Presentation in Pediatric Myocarditis. Seidel, F., Scheibenbogen, C., Heidecke, H., Opgen-Rhein, B., Pickardt, T., Klingel, K., Berger, F., Messroghli, D. & Schubert, S. Front Pediatr 10, 881208 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35573966
RNA modification mapping with JACUSA2. Piechotta, M., Naarmann-de Vries, I. S., Wang, Q., Altmuller, J. & Dieterich, C. Genome Biol 23, 115 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35578346
Very-high-power short-duration ablation for treatment of premature ventricular contractions - The FAST-AND-FURIOUS PVC study. Heeger, C. H., Popescu, S. S., Kirstein, B., Hatahet, S., Traub, A., Phan, H. L., Feher, M., G, D. A., Keelani, A., Schluter, M., Vogler, J., Eitel, C., Kuck, K. H. & Tilz, R. R. Int J Cardiol Heart Vasc 40, 101042 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35573650
Case Report: Transient Increase of CMR T1 Mapping Indices in a Patient With COVID-19 mRNA Vaccine Induced Acute Myocarditis. Ansari, U., Britsch, S., Rogowski, S., Duerschmied, D. & Papavassiliu, T. Front Cardiovasc Med 9, 880717 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35571183
Gender-Specific Performance of One- Compared to Two-Catheter Concepts in Transradial Coronary Angiography - Insights From the Randomized UDDC-Radial-Trial. Schneider, V. S., Lubking, L., Stahli, B. E., Skurk, C., Lauten, A., Mochmann, H. C., Schauerte, P., Riedel, M., Steinbeck, L., Rauch-Krohnert, U., Klotsche, J., Landmesser, U., Frohlich, G. & Leistner, D. M. Cardiovasc Revasc Med 43, 49-54 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35570153
Association between bone turnover markers and periodontitis: A population-based cross-sectional study. Reckelkamm, S. L., Hannemann, A., Kocher, T., Nauck, M., Volzke, H., Ehmke, B., Rauner, M., Alayash, Z., Baumeister, S. E., Nolde, M. & Holtfreter, B. J Clin Periodontol 49, 633-641 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35569034
Whole blood transcriptomic profiling identifies molecular pathways related to cardiovascular mortality in heart failure. Nath, M., Romaine, S. P. R., Koekemoer, A., Hamby, S., Webb, T. R., Nelson, C. P., Castellanos-Uribe, M., Papakonstantinou, M., Anker, S. D., Lang, C. C., Metra, M., Zannad, F., Filippatos, G., van Veldhuisen, D. J., Cleland, J. G., Ng, L. L., May, S. T., Marelli-Berg, F., Voors, A. A., Timmons, J. A. et al.Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35570197
Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis. Elkenani, M., Barakat, A. Z., Held, T., Rodrigues, D. M., Mobarak, S., Swarnka, S., Adham, I. M. & Mohamed, B. A. J Transl Med 20, 229 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35568953
Surgical aortic valve replacement in patients aged 50-69 years-insights from the German Aortic Valve Registry (GARY). Vogt, F., Santarpino, G., Fujita, B., Frerker, C., Bauer, T., Beckmann, A., Bekeredjian, R., Bleiziffer, S., Mollmann, H., Walther, T., Beyersdorf, F., Hamm, C., Boning, A., Baldus, S., Ensminger, S., Fischlein, T., Eckner, D. & Board, G. E. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35567484
Behavioral Health Risk Factors and Motivation to Change among Cardiovascular General Hospital Patients Aged 50 to 79 Years. Siewert-Markus, U., Ulbricht, S., Gaertner, B., Zyriax, B. C., Dorr, M., Tobschall, S., Baumann, S., John, U. & Freyer-Adam, J. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35565928
Comparable Analysis of Acute Changes in Vascular Tone after Coffee versus Energy Drink Consumption. Schuttler, D., Hamm, W., Kellnar, A., Brunner, S. & Stremmel, C. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35565863
Peripheral Serotonin Deficiency Affects Anxiety-like Behavior and the Molecular Response to an Acute Challenge in Rats. Sbrini, G., Hanswijk, S. I., Brivio, P., Middelman, A., Bader, M., Fumagalli, F., Alenina, N., Homberg, J. R. & Calabrese, F. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35563331
Overexpression of Renin-B Induces Warburg-like Effects That Are Associated with Increased AKT/mTOR Signaling. Golchert, J., Staar, D., Bennewitz, J., Hartmann, M., Hoffmann, N., Ameling, S., Volker, U., Peters, J. & Wanka, H. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35563765
Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques. Edsfeldt, A., Swart, M., Singh, P., Dib, L., Sun, J., Cole, J. E., Park, I., Al-Sharify, D., Persson, A., Nitulescu, M., Borges, P. D. N., Kassiteridi, C., Goddard, M. E., Lee, R., Volkov, P., Orho-Melander, M., Maegdefessel, L., Nilsson, J., Udalova, I., Goncalves, I. et al. Eur Heart J 43, 1864-1877 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35567557
In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using (68) Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages. Varasteh, Z., Braeuer, M., Mohanta, S., Steinsiek, A. L., Habenicht, A., Omidvari, N., Topping, G. J., Rischpler, C., Weber, W. A., Sager, H. B., Raes, G., Hernot, S. & Schwaiger, M. Front Cardiovasc Med 9, 889963 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35548425
Anticoagulation for Percutaneous Ventricular Assist Device-Supported Cardiogenic Shock: JACC Review Topic of the Week. Vandenbriele, C., Arachchillage, D. J., Frederiks, P., Giustino, G., Gorog, D. A., Gramegna, M., Janssens, S., Meyns, B., Polzin, A., Scandroglio, M., Schrage, B., Stone, G. W., Tavazzi, G., Vanassche, T., Vranckx, P., Westermann, D., Price, S. & Chieffo, A. J Am Coll Cardiol 79, 1949-1962 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35550692
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors. Poch, C. M., Foo, K. S., De Angelis, M. T., Jennbacken, K., Santamaria, G., Bahr, A., Wang, Q. D., Reiter, F., Hornaschewitz, N., Zawada, D., Bozoglu, T., My, I., Meier, A., Dorn, T., Hege, S., Lehtinen, M. L., Tsoi, Y. L., Hovdal, D., Hyllner, J., Schwarz, S. et al. Nat Cell Biol 24, 659-671 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35550611
Letter to the Editor. Response to "Diagnosis of CAV in OCT Scans From Heart Transplanted Patients". Orban, M. & Massberg, S. Transplant Direct 8, e1326 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35557990
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rueger, S., Speidel, L., Kim, Y. J., Horikoshi, M., Mercader, J. M., Taliun, D., Moon, S., Kwak, S. H., Robertson, N. R., Rayner, N. W., Loh, M., Kim, B. J., Chiou, J. et al. Nat Genet 54, 560-572 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35551307
Integrated care for optimizing the management of stroke and associated heart disease: a position paper of the European Society of Cardiology Council on Stroke. Lip, G. Y. H., Lane, D. A., Lenarczyk, R., Boriani, G., Doehner, W., Benjamin, L. A., Fisher, M., Lowe, D., Sacco, R. L., Schnabel, R., Watkins, C., Ntaios, G. & Potpara, T. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35552401
Periprocedural Strategies for Stroke Prevention in Patients Undergoing Transcatheter Aortic Valve Implantation. Linder, M. & Seiffert, M. Front Cardiovasc Med 9, 892956 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35557539
Paediatric inflammatory multisystem syndrome - temporally associated with SARS-CoV-2 (PIMS-TS) - a German single centre real-life evaluation of the Swiss and UK consensus statements. Jenke, A. & Steinmetz, M. Cardiol Young, 1-5 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35546290
Integrative analysis of clinical and epigenetic biomarkers of mortality. Huan, T., Nguyen, S., Colicino, E., Ochoa-Rosales, C., Hill, W. D., Brody, J. A., Soerensen, M., Zhang, Y., Baldassari, A., Elhadad, M. A., Toshiko, T., Zheng, Y., Domingo-Relloso, A., Lee, D. H., Ma, J., Yao, C., Liu, C., Hwang, S. J., Joehanes, R., Fornage, M. et al. Aging Cell 21, e13608 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35546478
Zfp580 Regulates Paracrine and Endocrine Igf1 and Igfbp3 Differently in the Brain and Blood After a Murine Stroke. Hoffmann, C. J., Kuffner, M. T. C., Lips, J., Lorenz, S., Endres, M. & Harms, C. Front Physiol13, 887180 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35557964
Paradigm shift: new concepts for HCN4 function in cardiac pacemaking. Hennis, K., Biel, M., Fenske, S. & Wahl-Schott, C. Pflugers Arch 474, 649-663 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35556164
Rapid Inflammasome Activation Is Attenuated in Post-Myocardial Infarction Monocytes. Giral, H., Franke, V., Moobed, M., Muller, M. F., Lubking, L., James, D. M., Hartung, J., Kuschnerus, K., Meteva, D., Seppelt, C., Jakob, P., Klingenberg, R., Krankel, N., Leistner, D., Zeller, T., Blankenberg, S., Zimmermann, F., Haghikia, A., Luscher, T. F., Akalin, A. et al. Front Immunol 13, 857455 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35558073
The Increasing Role of Rhythm Control in Patients With Atrial Fibrillation: JACC State-of-the-Art Review. Camm, A. J., Naccarelli, G. V., Mittal, S., Crijns, H., Hohnloser, S. H., Ma, C. S., Natale, A., Turakhia, M. P. & Kirchhof, P. J Am Coll Cardiol 79, 1932-1948 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35550691
Graded lower body negative pressure induces intraventricular negative pressures and incremental diastolic suction: a pressure-volume study in a porcine model. Berboth, L., Zirngast, B., Manninger, M., Steendijk, P., Tschope, C., Scherr, D., Hinghofer-Szalkay, H. G., Goswami, N., Petersen, L. G., Machler, H. & Alogna, A. J Appl Physiol (1985) 133, 20-26 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35546125
Molybdenum Cofactor Catabolism Unravels the Physiological Role of the Drug Metabolizing Enzyme Thiopurine S-Methyltransferase. Pristup, J., Schaeffeler, E., Arjune, S., Hofmann, U., Angel Santamaria-Araujo, J., Leuthold, P., Friedrich, N., Nauck, M., Mayr, S., Haag, M., Muerdter, T., Marner, F. J., Relling, M. V., Evans, W. E., Schwarz, G. & Schwab, M. Clin Pharmacol Ther (2022). https://www.ncbi.nlm.nih.gov/pubmed/35538648
Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project). Bernabei, R., Landi, F., Calvani, R., Cesari, M., Del Signore, S., Anker, S. D., Bejuit, R., Bordes, P., Cherubini, A., Cruz-Jentoft, A. J., Di Bari, M., Friede, T., Gorostiaga Ayestaran, C., Goyeau, H., Jonsson, P. V., Kashiwa, M., Lattanzio, F., Maggio, M., Mariotti, L., Miller, R. R. et al. BMJ 377, e068788 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35545258
Reference Values for Pediatric Atrial Volumes Assessed by Steady-State Free-Precession Magnetic Resonance Imaging Using Monoplane and Biplane Area-Length Methods. Voges, I., Caliebe, A., Hinz, S., Boroni Grazioli, S., Gabbert, D. D., Wegner, P., Uebing, A. S., Daubeney, P. E. F., Pennell, D. J. & Krupickova, S. J Magn Reson Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35535720
Association of C-Terminal Pro-Endothelin-1 with Mortality in the Population-Based KORA F4 Study. Then, C., Sujana, C., Herder, C., Then, H., Heier, M., Meisinger, C., Peters, A., Koenig, W., Rathmann, W., Maalmi, H., Ritzel, K., Roden, M., Stumvoll, M., Thorand, B. & Seissler, J. Vasc Health Risk Manag 18, 335-346 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35535305
Intravenous immunoglobulins for treatment of severe COVID-19-related acute encephalopathy.Huo, S., Ferse, C., Bosl, F., Reincke, S. M., Enghard, P., Hinrichs, C., Treskatsch, S., Angermair, S., Eckardt, K. U., Audebert, H. J., Ploner, C. J., Endres, M., Pruss, H., Franke, C. & Scheibe, F. J Neurol, 1-8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35538168
Sphingosine-1-phosphate and vascular disease in the general population. Rotheudt, L., Moritz, E., Markus, M. R. P., Albrecht, D., Volzke, H., Friedrich, N., Schwedhelm, E., Daum, G., Schminke, U., Felix, S. B., Rauch, B. H., Dorr, M. & Bahls, M. Atherosclerosis 350, 73-81 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35533519
Combined Oral Triglyceride and Glucose Tolerance Test After Acute Ischemic Stroke to Predict Recurrent Vascular Events: The Berlin "Cream&Sugar" Study. Nave, A. H., Kaynak, N., Mai, K., Siegerink, B., Laufs, U., Heuschmann, P. U., Liman, T. G., Ebinger, M. & Endres, M. Stroke, 101161STROKEAHA122038732 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35531780
Long noncoding RNAs in cardiometabolic disorders. Juni, R. P., t Hart, K. C., Houtkooper, R. H. & Boon, R. A. FEBS Lett 596, 1367-1387 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35531641
The splicing-regulatory lncRNA NTRAS sustains vascular integrity. Fouani, Y., Kirchhof, L., Stanicek, L., Luxan, G., Heumuller, A. W., Knau, A., Fischer, A., Devraj, K., John, D., Neumann, P., Bindereif, A., Boon, R. A., Liebner, S., Wittig, I., Mogler, C., Karimova, M., Dimmeler, S. & Jae, N. EMBO Rep 23, e54157 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35527520
Propofol versus midazolam sedation in patients with cardiogenic shock - an observational propensity-matched study. Scherer, C., Kleeberger, J., Kellnar, A., Binzenhofer, L., Lusebrink, E., Stocker, T. J., Berghoff, S. A., Keutner, A., Thienel, M., Deseive, S., Stark, K., Braun, D., Orban, M., Petzold, T., Brunner, S., Hagl, C., Hausleiter, J., Massberg, S. & Orban, M. J Crit Care 71, 154051 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35526506
Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study. Steinbrenner, I., Sekula, P., Kotsis, F., von Cube, M., Cheng, Y., Nadal, J., Schmid, M., Schneider, M. P., Krane, V., Nauck, M., Eckardt, K. U., Schultheiss, U. T. & investigators, G. Nephrol Dial Transplant (2022). https://www.ncbi.nlm.nih.gov/pubmed/35524694
Association of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis. Kuramatsu, J. B., Gerner, S. T., Ziai, W., Bardutzky, J., Sembill, J. A., Sprugel, M. I., Mrochen, A., Kolbl, K., Ram, M., Avadhani, R., Falcone, G. J., Selim, M. H., Lioutas, V. A., Endres, M., Zweynert, S., Vajkoczy, P., Ringleb, P. A., Purrucker, J. C., Volkmann, J., Neugebauer, H. et al. Stroke 53, 2876-2886 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35521958
A prospective case-control validation of procalcitonin as a biomarker diagnosing pacemaker and implantable cardioverter defibrillator pocket infection. Knoll, K., O'Connor, M., Chouchane, A., Haller, B., Schaarschmidt, C., Bock, M., Forschner, L., Frohlich, R., Kottmaier, M., Bourier, F., Reents, T., Hessling, G., Deisenhofer, I., Kolb, C. & Lennerz, C. Kardiol Pol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35521718
The Atrial Fibrillation Heart Team-guiding therapy in left atrial appendage occlusion with increasingly complex patients and little evidence. Kany, S., Metzner, A., Lubos, E. & Kirchhof, P. Eur Heart J 43, 1691-1692 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35523426
Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes. Schade, D., Drowley, L., Wang, Q. D., Plowright, A. T. & Greber, B. Bioorg Med Chem 65, 116782 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35512484
Heart Sweet Heart - Cardiac long-term effects of sugar kisses. Markus, M. R. P. & Dorr, M. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35512424
Long-Term Outcomes of Patients With Elevated Mitral Valve Pressure Gradient After Mitral Valve Edge-to-Edge Repair. Koell, B., Ludwig, S., Weimann, J., Waldschmidt, L., Hildebrandt, A., Schofer, N., Schirmer, J., Westermann, D., Reichenspurner, H., Blankenberg, S., Conradi, L., Lubos, E. & Kalbacher, D. JACC Cardiovasc Interv 15, 922-934 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35512916
Treatment of the aortic root in acute aortic dissection type A: insights from the German Registry for Acute Aortic Dissection Type A. Kallenbach, K., Busch, C., Rylski, B., Dohle, D. S., Kruger, T., Holubec, T., Brickwedel, J., Poling, J., Noack, T., Hagl, C., Jawny, P., Boning, A., Chalabi, K., Karck, M. & Arif, R. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35511255
Treating depression in patients with heart failure: what is (not) recommended? Herrmann-Lingen, C. Eur J Prev Cardiol 29, 2137-2139 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35512436
Perceived vs. objective frailty in patients with atrial fibrillation and impact on anticoagulant dosing: an ETNA-AF-Europe sub-analysis. Diemberger, I., Fumagalli, S., Mazzone, A. M., Bakhai, A., Reimitz, P. E., Pecen, L., Manu, M. C., Gordillo de Souza, J. A., Kirchhof, P. & De Caterina, R. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/35512229
Course of disease and risk factors for hospitalization in outpatients with a SARS-CoV-2 infection. Schafer, E., Scheer, C., Salje, K., Fritz, A., Kohlmann, T., Hubner, N. O., Napp, M., Fiedler-Lacombe, L., Stahl, D., Rauch, B., Nauck, M., Volker, U., Felix, S., Lucchese, G., Floel, A., Engeli, S., Hoffmann, W., Hahnenkamp, K. & Tzvetkov, M. V. Sci Rep 12, 7249 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35508524
Right on target: The next class of efficient, safe, and specific RNAi triggers. Becker, J., Fischer, N. & Grimm, D. Mol Ther Nucleic Acids 28, 363-365 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35505965
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. Wielscher, M., Mandaviya, P. R., Kuehnel, B., Joehanes, R., Mustafa, R., Robinson, O., Zhang, Y., Bodinier, B., Walton, E., Mishra, P. P., Schlosser, P., Wilson, R., Tsai, P. C., Palaniswamy, S., Marioni, R. E., Fiorito, G., Cugliari, G., Karhunen, V., Ghanbari, M., Psaty, B. M. et al. Nat Commun 13, 2408 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35504910
Cerebral oxygen saturation as outcome predictor after transfemoral transcatheter aortic valve implantation. Seppelt, P. C., Mas-Peiro, S., Van Linden, A., Iken, S., Zacharowski, K., Walther, T., Fichtlscherer, S. & Vasa-Nicotera, M. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35505123
Predictors of primary prevention implantable cardioverter-defibrillator use in heart failure with reduced ejection fraction: impact of the predicted risk of sudden cardiac death and all-cause mortality. Schrage, B., Lund, L. H., Benson, L., Dahlstrom, U., Shadman, R., Linde, C., Braunschweig, F., Levy, W. C. & Savarese, G. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35502681
Myeloid differentiation factor-2 activates monocytes in patients with dilated cardiomyopathy. Feldtmann, R., Kummel, A., Chamling, B., Strohbach, A., Lehnert, K., Gross, S., Loerzer, L., Riad, A., Lindner, D., Westermann, D., Fielitz, J., Dorr, M. & Felix, S. B. Immunology 167, 40-53 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35502635
Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathy. Jung, P., Seibertz, F., Fakuade, F. E., Ignatyeva, N., Sampathkumar, S., Ritter, M., Li, H., Mason, F. E., Ebert, A. & Voigt, N. Basic Res Cardiol 117, 5 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35499658
Association Between the Acidemia, Lactic Acidosis, and Shock Severity With Outcomes in Patients With Cardiogenic Shock. Jentzer, J. C., Schrage, B., Patel, P. C., Kashani, K. B., Barsness, G. W., Holmes, D. R., Jr., Blankenberg, S., Kirchhof, P. & Westermann, D. J Am Heart Assoc 11, e024932 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35491996
Diagnostic role of echocardiography for patients with heart failure symptoms and preserved left ventricular ejection fraction. Hagendorff, A., Stobe, S., Kandels, J., de Boer, R. & Tschope, C. Herz (2022). https://www.ncbi.nlm.nih.gov/pubmed/35499562
ExomeChip-based rare variant association study in restless legs syndrome. Tilch, E., Schormair, B., Zhao, C., Hogl, B., Stefani, A., Berger, K., Trenkwalder, C., Bachmann, C. G., Hornyak, M., Fietze, I., Muller-Nurasyid, M., Peters, A., Herms, S., Nothen, M. M., Muller-Myhsok, B., Oexle, K. & Winkelmann, J. Sleep Med94, 26-30 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35489115
Up next: The dawn of systems biology in HFpEF research. Bode, D., Sotomayor-Flores, C. & Schiattarella, G. G. J Mol Cell Cardiol 168, 96-97 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35489386
Cardiac remodelling - Part 2: Clinical, imaging and laboratory findings. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology. Aimo, A., Vergaro, G., Gonzalez, A., Barison, A., Lupon, J., Delgado, V., Richards, A. M., de Boer, R. A., Thum, T., Arfsten, H., Hulsmann, M., Falcao-Pires, I., Diez, J., Foo, R. S. Y., Chan, M. Y. Y., Anene-Nzelu, C. G., Abdelhamid, M., Adamopoulos, S., Anker, S. D., Belenkov, Y. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35488811
Juni
Paper of the Month
Diagnostic Value of sST2, VCAM-1, and Adiponectin in Patients with Breast Cancer to Predict Anti-Tumour Treatment-Related Cardiac Events: A Pilot Study. Rosenkaimer, S. L., Winter, L., Sieburg, T., Maier, S., Mavratzas, A., Hofmann, W. K., Akin, I., Duerschmied, D., Hofheinz, R. D. & Hohneck, A. Oncol Res Treat 45, 598-607 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35764064
Immunometabolic Mechanisms of Heart Failure with Preserved Ejection Fraction. Schiattarella, G. G., Alcaide, P., Condorelli, G., Gillette, T. G., Heymans, S., Jones, E. A. V., Kallikourdis, M., Lichtman, A., Marelli-Berg, F., Shah, S., Thorp, E. B. & Hill, J. A. Nat Cardiovasc Res 1, 211-222 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35755006
Validation of Cardiovascular Risk Prediction by the Arriba Instrument. Angelow, A., Klotzer, C., Donner-Banzhoff, N., Haasenritter, J., Schmidt, C. O., Dorr, M. & Chenot, J. F. Dtsch Arztebl Int 119, 476-482 (2022). www.ncbi.nlm.nih.gov/pubmed/35635438
Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF). Schulze, P. C., Bogoviku, J., Westphal, J., Aftanski, P., Haertel, F., Grund, S., von Haehling, S., Schumacher, U., Mobius-Winkler, S. & Busch, M. Circulation 146, 289-298 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35766022
First clinical experience of high-power ablation of atrial fibrillation with a novel contact force-sensing gold-tip catheter. Parwani, A. S., Jayanata, A., Kraft, R., Lacour, P., Blaschke, F., Pieske, B. & Boldt, L. H. Cardiol J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35762071
Empagliflozin for Heart Failure With Preserved Left Ventricular Ejection Fraction With and Without Diabetes. Filippatos, G., Butler, J., Farmakis, D., Zannad, F., Ofstad, A. P., Ferreira, J. P., Green, J. B., Rosenstock, J., Schnaidt, S., Brueckmann, M., Pocock, S. J., Packer, M., Anker, S. D., Committees, E. M.-P. T. & Investigators. Circulation 146, 676-686 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35762322
Association of birth weight with corneal aberrations in adulthood – Results from a population-based study. Fieß, A., Urschitz, M. S., Nagler, M., Nickels, S., Marx-Groß, S., Münzel, T., Wild, P. S., Beutel, M. E., Lackner, K. J., Pfeiffer, N. & Schuster, A. K. Journal of Optometry (2022).
Endothelin B Receptor Immunodynamics in Pulmonary Arterial Hypertension. Tabeling, C., Gonzalez Calera, C. R., Lienau, J., Hoppner, J., Tschernig, T., Kershaw, O., Gutbier, B., Naujoks, J., Herbert, J., Opitz, B., Gruber, A. D., Hocher, B., Suttorp, N., Heidecke, H., Burmester, G. R., Riemekasten, G., Siegert, E., Kuebler, W. M. & Witzenrath, M. Front Immunol 13, 895501 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35757687
LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide. Quaife, N. M., Chothani, S., Schulz, J. F., Lindberg, E. L., Vanezis, K., Adami, E., O'Fee, K., Greiner, J., Litvinukova, M., van Heesch, S., Whiffin, N., Hubner, N., Schafer, S., Rackham, O., Cook, S. A. & Barton, P. J. R. J Cardiovasc Transl Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35759180
Targeted Analysis of circRNA Expression in Patient Samples by Lexo-circSeq. Naarmann-de Vries, I. S., Eschenbach, J., Schudy, S., Meder, B. & Dieterich, C. Front Mol Biosci 9, 875805 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35755822
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model. Hao, Y., Sun, X., Kiekenap, J. F. S., Emeis, J., Steitz, M., Breitenstein-Attach, A., Berger, F. & Schmitt, B. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35758699
Respiratory and heart rate dynamics during peripheral chemoreceptor deactivation compared to targeted sympathetic and sympathetic/parasympathetic (co-)activation. Apelt-Glitz, K., Alken, F. A., Jungen, C., Scherschel, K., Klocker, N. & Meyer, C. Auton Neurosci 241, 103009 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35753247
Prevention of sudden death in heart failure with reduced ejection fraction: Do we still need ICD for primary prevention? Abdelhamid, M., Rosano, G., Metra, M., Adamopoulos, S., Bohm, M., Chioncel, O., Filippatos, G., Jankowska, E. A., Lopatin, Y., Lund, L., Milicic, D., Moura, B., Ben Gal, T., Ristic, A., Rakisheva, A., Savarese, G., Mullens, W., Piepoli, M., Bayes-Genis, A., Thum, T. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35753058
Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood-brain barrier in acute ischemic stroke. Spitzer, D., Guerit, S., Puetz, T., Khel, M. I., Armbrust, M., Dunst, M., Macas, J., Zinke, J., Devraj, G., Jia, X., Croll, F., Sommer, K., Filipski, K., Freiman, T. M., Looso, M., Gunther, S., Di Tacchio, M., Plate, K. H., Reiss, Y., Liebner, S. et al. Acta Neuropathol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35752654
ClearCNV: CNV calling from NGS panel data in the presence of ambiguity and noise. May, V., Koch, L., Fischer-Zirnsak, B., Horn, D., Gehle, P., Kornak, U., Beule, D. & Holtgrewe, M. Bioinformatics (2022). https://www.ncbi.nlm.nih.gov/pubmed/35751599
Riociguat attenuates left ventricular proteome and microRNA profile changes after experimental aortic stenosis in mice. Benkner, A., Rudebusch, J., Nath, N., Hammer, E., Grube, K., Gross, S., Dhople, V. M., Eckstein, G., Meitinger, T., Kaderali, L., Volker, U., Fielitz, J. & Felix, S. B. Br J Pharmacol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35751875
Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor. Behrendsen, L. S., Menon, P. R., Khan, M. J., Gregus, A., Wirths, O., Meyer, T. & Staab, J. BMC Mol Cell Biol 23, 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35752777
In Vivo Inhibition of TRPC6 by SH045 Attenuates Renal Fibrosis in a New Zealand Obese (NZO) Mouse Model of Metabolic Syndrome. Zheng, Z., Xu, Y., Krugel, U., Schaefer, M., Grune, T., Nurnberg, B., Kohler, M. B., Gollasch, M., Tsvetkov, D. & Marko, L. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35743312
Transcatheter Mitral Valve Repair or Replacement: Competitive or Complementary? Xiling, Z., Puehler, T., Sondergaard, L., Frank, D., Seoudy, H., Mohammad, B., Muller, O. J., Sellers, S., Meier, D., Sathananthan, J. & Lutter, G. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35743448
Measurement of Tetrahydrobiopterin in Animal Tissue Samples by HPLC with Electrochemical Detection-Protocol Optimization and Pitfalls. Vujacic-Mirski, K., Oelze, M., Kuntic, I., Kuntic, M., Kalinovic, S., Li, H., Zielonka, J., Munzel, T. & Daiber, A. Antioxidants (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35740082
Impact of different training modalities on high-density lipoprotein function in HFpEF patients: a substudy of the OptimEx trial. Sowa, P. W., Winzer, E. B., Hommel, J., Mannel, A., van Craenenbroeck, E. M., Wisloff, U., Pieske, B., Halle, M., Linke, A. & Adams, V. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35747946
Surgery for Aortic Prosthetic Valve Endocarditis in the Transcatheter Era. Saha, S., Ali, A., Schnackenburg, P., Horke, K. M., Oberbach, A., Schlichting, N., Sadoni, S., Rizas, K., Braun, D., Luehr, M., Bagaev, E., Hagl, C. & Joskowiak, D. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35743488
Exploring the Potential of Symmetric Exon Deletion to Treat Non-Ischemic Dilated Cardiomyopathy by Removing Frameshift Mutations in TTN. Rodriguez-Polo, I. & Behr, R. Genes (Basel) 13 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35741855
Platelets and the Role of P2X Receptors in Nociception, Pain, Neuronal Toxicity and Thromboinflammation. Rawish, E. & Langer, H. F. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35743029
Modulation of Rxralpha Expression in Mononuclear Phagocytes Impacts on Cardiac Remodeling after Ischemia-Reperfusion Injury. Rauber, S., Fischer, M., Messerer, D., Wimmler, V., Konda, K., Todica, A., Lorenz, M., Titova, A., Schulz, C. & Weinberger, T. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35740296
Early and Strong Leptin Reduction Is Predictive for Long-Term Weight Loss during High-Protein, Low-Glycaemic Meal Replacement-A Subanalysis of the Randomised-Controlled ACOORH Trial. Kempf, K., Rohling, M., Banzer, W., Braumann, K. M., Halle, M., Schaller, N., McCarthy, D., Predel, H. G., Schenkenberger, I., Tan, S., Toplak, H., Martin, S., Berg, A. & Acoorh Study, G. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35745267
NADPH Oxidases in Pain Processing. Kallenborn-Gerhardt, W., Schroder, K. & Schmidtko, A. Antioxidants (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35740059
Clinical implications of left atrial changes after optimization of medical therapy in patients with heart failure. Inciardi, R. M., Pagnesi, M., Lombardi, C. M., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., Lang, C. C., Ng, L. L., Pellicori, P., Ponikowski, P., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Solomon, S. D., Voors, A. A. & Metra, M. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35748048
Ethyl Hydroxyethyl Cellulose-A Biocompatible Polymer Carrier in Blood. Eckelt, A., Wichmann, F., Bayer, F., Eckelt, J., Gross, J., Opatz, T., Jurk, K., Reinhardt, C. & Kiouptsi, K. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35742876
Molecular Detection of Venous Thrombosis in Mouse Models Using SPECT/CT. Dickhout, A., Van de Vijver, P., Bitsch, N., van Hoof, S. J., Thomassen, S., Massberg, S., Timmerman, P., Verhaegen, F., Koenen, R. R., Dijkgraaf, I. & Hackeng, T. M. Biomolecules 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35740954
Blinded by the Lights: OCT-Guidance for Implantation of Magnesium-Based Bioresorbable Scaffolds? Seguchi, M. & Joner, M. Cardiovasc Revasc Med 40, 111-112 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35738727
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs. Kokot, K. E., Kneuer, J. M., John, D., Rebs, S., Mobius-Winkler, M. N., Erbe, S., Muller, M., Andritschke, M., Gaul, S., Sheikh, B. N., Haas, J., Thiele, H., Muller, O. J., Hille, S., Leuschner, F., Dimmeler, S., Streckfuss-Bomeke, K., Meder, B., Laufs, U. & Boeckel, J. N. Basic Res Cardiol 117, 32 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35737129
Kidney Failure among Patients with Takotsubo Syndrome or Myocardial Infarction: A Retrospective Analysis. Bill, V., El-Battrawy, I., Kummer, M., Mugge, A., Aweimer, A., Behnes, M. & Akin, I. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35735815
Side effects and treatment initiation barriers of SGLT2 inhibitors in heart failure: A systematic review and meta-analysis. Vukadinovic, D., Abdin, A., Anker, S. D., Rosano, G. M., Mahfoud, F., Packer, M., Butler, J. & Bohm, M. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35730422
Clonal haematopoiesis is associated with higher mortality in patients with cardiogenic shock. Scolari, F. L., Abelson, S., Brahmbhatt, D. H., Medeiros, J. J. F., Fan, C. S., Fung, N. L., Mihajlovic, V., Anker, M. S., Otsuki, M., Lawler, P. R., Ross, H. J., Luk, A. C., Anker, S., Dick, J. E. & Billia, F. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35729851
German Cardiac Arrest Registry: rationale and design of G-CAR. Poss, J., Sinning, C., Schreiner, I., Apfelbacher, C., Drewitz, K. P., Hosler, N., Schneider, S., Pieske, B., Bottiger, B. W., Ewen, S., Wienbergen, H., Kelm, M., Bock, D., Graf, T., Adler, C., Dutzmann, J., Knie, W., Orban, M., Zeymer, U., Michels, G. et al. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35729429
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy. Perea-Gil, I., Seeger, T., Bruyneel, A. A. N., Termglinchan, V., Monte, E., Lim, E. W., Vadgama, N., Furihata, T., Gavidia, A. A., Arthur Ataam, J., Bharucha, N., Martinez-Amador, N., Ameen, M., Nair, P., Serrano, R., Kaur, B., Feyen, D. A. M., Diecke, S., Snyder, M. P., Metallo, C. M. et al. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35728000
A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth. Ong, Y. T., Andrade, J., Armbruster, M., Shi, C., Castro, M., Costa, A. S. H., Sugino, T., Eelen, G., Zimmermann, B., Wilhelm, K., Lim, J., Watanabe, S., Guenther, S., Schneider, A., Zanconato, F., Kaulich, M., Pan, D., Braun, T., Gerhardt, H., Efeyan, A. et al. Nat Metab 4, 672-682 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35726026
Elucidation of the genetic causes of bicuspid aortic valve disease. Gehlen, J., Stundl, A., Debiec, R., Fontana, F., Krane, M., Sharipova, D., Nelson, C. P., Al-Kassou, B., Giel, A. S., Sinning, J. M., Bruenger, C. M., Zelck, C. F., Koebbe, L. L., Braund, P. S., Webb, T. R., Hetherington, S., Ensminger, S., Fujita, B., Mohamed, S. A., Shrestha, M. et al. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35727948
Feasible approaches and implementation challenges to atrial fibrillation screening: a qualitative study of stakeholder views in 11 European countries. Engler, D., Hanson, C. L., Desteghe, L., Boriani, G., Diederichsen, S. Z., Freedman, B., Pala, E., Potpara, T. S., Witt, H., Heidbuchel, H., Neubeck, L., Schnabel, R. B. & investigators, A.-E. BMJ Open 12, e059156 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35728895
Blood flow meets mitophagy. Akmeric, E. B. & Gerhardt, H. J Cell Biol 221 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35727256
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes. Weninger, G., Pochechueva, T., El Chami, D., Luo, X., Kohl, T., Brandenburg, S., Urlaub, H., Guan, K., Lenz, C. & Lehnart, S. E. Sci Rep 12, 10387 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35725601
Variation in Mean Arterial Pressure Increases Falls Risk in Elderly Physically Frail and Prefrail Individuals Treated With Antihypertensive Medication. Hussain, S. M., Ernst, M. E., Barker, A. L., Margolis, K. L., Reid, C. M., Neumann, J. T., Tonkin, A. M., Phuong, T. L. T., Beilin, L. J., Pham, T., Chowdhury, E. K., Cicuttini, F. M., Gilmartin-Thomas, J., Carr, P. R. & McNeil, J. J. Hypertension, 101161HYPERTENSIONAHA12219356 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35722878
Preparation of Human Myocardial Tissue for Long-term Cultivation. Hamers, J., Sen, P., Merkus, D., Seidel, T., Lu, K. & Dendorfer, A. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/35723462
Predictors of post-stroke delirium incidence and duration: Results of a prospective observational study using high-frequency delirium screening. Fleischmann, R., Andrasch, T., Warwas, S., Kunz, R., Gross, S., Witt, C., Ruhnau, J., Vogelgesang, A., Ulm, L., Mengel, A. & von Sarnowski, B. Int J Stroke, 17474930221109353 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35722813
Serum anti-NMDA-receptor antibodies and cognitive function after ischemic stroke (PROSCIS-B). Sperber, P. S., Gebert, P., Broersen, L. H. A., Huo, S., Piper, S. K., Teegen, B., Heuschmann, P. U., Pruss, H., Endres, M., Liman, T. G. & Siegerink, B. J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35718820
Closing the gap or the beauty of alleviating our patients' symptoms. Petutschnigg, J. & Edelmann, F. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35717602
Treatment Planning for Cardiac Radioablation: Multicenter Multiplatform Benchmarking for the XXX Trial. Kluge, A., Ehrbar, S., Grehn, M., Fleckenstein, J., Baus, W. W., Siebert, F. A., Schweikard, A., Andratschke, N., Mayinger, M. C., Boda-Heggemann, J., Buergy, D., Celik, E., Krug, D., Kovacs, B., Saguner, A. M., Rudic, B., Bergengruen, P., Boldt, L. H., Stauber, A., Zaman, A. et al. Int J Radiat Oncol Biol Phys (2022). https://www.ncbi.nlm.nih.gov/pubmed/35716847
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. Gorski, M., Rasheed, H., Teumer, A., Thomas, L. F., Graham, S. E., Sveinbjornsson, G., Winkler, T. W., Gunther, F., Stark, K. J., Chai, J. F., Tayo, B. O., Wuttke, M., Li, Y., Tin, A., Ahluwalia, T. S., Arnlov, J., Asvold, B. O., Bakker, S. J. L., Banas, B., Bansal, N. et al. Kidney Int(2022). https://www.ncbi.nlm.nih.gov/pubmed/35716955
TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy. Zhang, L., Dietsche, F., Seitaj, B., Rojas-Charry, L., Latchman, N., Tomar, D., Wust, R. C., Nickel, A., Frauenknecht, K. B., Schoser, B., Schumann, S., Schmeisser, M. J., Vom Berg, J., Buch, T., Finger, S., Wenzel, P., Maack, C., Elrod, J. W., Parys, J. B., Bultynck, G. et al. Life Sci Alliance 5 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35715207
Pediatric Cardiac Magnetic Resonance Reference Values for Biventricular Volumes Derived From Different Contouring Techniques. Voges, I., Caliebe, A., Hinz, S., Boroni Grazioli, S., Gabbert, D. D., Daubeney, P. E. F., Uebing, A. S., Pennell, D. J. & Krupickova, S. J Magn Reson Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35713958
Heterogeneity in coronary heart disease risk. Simonetto, C., Rospleszcz, S., Kaiser, J. C. & Furukawa, K. Sci Rep 12, 10131 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35710917
Management of pericardial tamponade in the electrophysiology laboratory: results from a national survey. Metzner, A., Reubold, S. D., Schonhofer, S., Reissmann, B., Ouyang, F., Rottner, L., Schleberger, R., Dinshaw, L., Moser, J., Moser, F., Lemoine, M., Munkler, P., Kany, S., Steven, D., Sommer, P., Kirchhof, P. & Rillig, A. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35713695
Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension. Liu, Y., Shi, J. Z., Jiang, R., Liu, S. F., He, Y. Y., van der Vorst, E. P. C., Weber, C., Doring, Y. & Yan, Y. Front Pharmacol 13, 908783 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35712711
Brief Research Report: Quantitative Analysis of Potential Coronary Microvascular Disease in Suspected Long-COVID Syndrome. Doeblin, P., Steinbeis, F., Scannell, C. M., Goetze, C., Al-Tabatabaee, S., Erley, J., Faragli, A., Propper, F., Witzenrath, M., Zoller, T., Stehning, C., Gerhardt, H., Sanchez-Gonzalez, J., Alskaf, E., Kuhne, T., Pieske, B., Tschope, C., Chiribiri, A. & Kelle, S. Front Cardiovasc Med 9, 877416 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35711381
Minimally-invasive mitral valve surgery after failed transcatheter mitral valve repair in an intermediate-risk cohort. Akansel, S., Kofler, M., Van Praet, K. M., Unbehaun, A., Sundermann, S. H., Jacobs, S., Falk, V. & Kempfert, J. Interact Cardiovasc Thorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35713519
Spatial profiling of early primate gastrulation in utero. Bergmann, S., Penfold, C. A., Slatery, E., Siriwardena, D., Drummer, C., Clark, S., Strawbridge, S. E., Kishimoto, K., Vickers, A., Tewary, M., Kohler, T. N., Hollfelder, F., Reik, W., Sasaki, E., Behr, R. & Boroviak, T. E. Nature (2022). https://www.ncbi.nlm.nih.gov/pubmed/35709828
Impact of COVID-19 on young healthcare professionals. Bahls, M., Gaber, M. H., Jorstad, H. T., Mouine, N., Scherrenberg, M. & Marques-Sule, E. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35708732
Impact of Artificial Intelligence Assistance on Chest CT Interpretation Times: A Prospective Randomized Study. Yacoub, B., Varga-Szemes, A., Schoepf, U. J., Kabakus, I. M., Baruah, D., Burt, J. R., Aquino, G. J., Sullivan, A. K., J, O. D., Hoelzer, P., Sperl, J. & Emrich, T. AJR Am J Roentgenol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35703413
The association between markers of type I collagen synthesis and echocardiographic response to spironolactone in patients at risk of heart failure: findings from the HOMAGE trial. Kobayashi, M., Girerd, N., Ferreira, J. P., Kevin, D., Huttin, O., Gonzalez, A., Bozec, E., Clark, A. L., Cosmi, F., Cuthbert, J., Diez, J., Edelmann, F., Hazebroek, M., Heymans, S., Mariottoni, B., Pellicori, P., Petutschnigg, J., Pieske, B., Staessen, J. A., Verdonschot, J. A. J. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35703355
Patient-Centered Outcomes in a Randomized Trial Investigating a Multimodal Prevention Program After Transient Ischemic Attack or Minor Stroke: The INSPiRE-TMS Trial. Ihl, T., Ahmadi, M., Laumeier, I., Steinicke, M., Ferse, C., Klyscz, P., Endres, M., Hastrup, S., Poppert, H., Palm, F., Kandil, F. I., Weber, J. E., von Weitzel-Mudersbach, P., Wimmer, M. L. J. & Audebert, H. J. Stroke, 101161STROKEAHA120037503 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35703097
COVID-19 Knowledge, Attitudes, and Preventive Measures of University Students in Bahrain. Perna, S., Bahar, K., Alalwan, T. A., Zahid, M. N., Gasparri, C., Peroni, G., Faragli, A., La Porta, E., Ali Redha, A., Janahi, E. M., Ibrahim, S. & Rondanelli, M. Ann Ig 34, 398-409 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35700030
Dose Reduction and Image Quality in Photon-counting Detector High-resolution Computed Tomography of the Chest: Routine Clinical Data. Graafen, D., Emrich, T., Halfmann, M. C., Mildenberger, P., Duber, C., Yang, Y., Othman, A. E., J, O. D., Muller, L. & Kloeckner, R. J Thorac Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35699680
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J. F., Sieber, K. B., Horn, K., Li, M., Scholz, M., Cocca, M., Wuttke, M. et al. Commun Biol 5, 580 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35697829
Sotrovimab in pediatric cardiac transplant recipients with SARS-CoV2 infection. Weber, S. C., Danne, F., Kieslich, M., Krauss, A., Berger, F. & Sallmon, H. J Heart Lung Transplant (2022). https://www.ncbi.nlm.nih.gov/pubmed/35697603
Ablation of Outflow Tract Arrhythmias in Patients With and Without Structural Heart Disease-A Comparative Analysis. Schleberger, R., Riess, J., Brauer, A., Pinnschmidt, H. O., Rottner, L., Moser, F., Moser, J., Kany, S., My, I., Lemoine, M. D., Reissmann, B., Meyer, C., Metzner, A., Ouyang, F., Kirchhof, P. & Rillig, A. Front Cardiovasc Med 9, 910042 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35694678
Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis. Pallares Robles, A., Ten Cate, V., Schulz, A., Prochaska, J. H., Rapp, S., Koeck, T., Panova-Noeva, M., Heitmeier, S., Schwers, S., Leineweber, K., Seyfarth, H. J., Opitz, C. F., Spronk, H., Espinola-Klein, C., Lackner, K. J., Munzel, T., Andrade-Navarro, M. A., Konstantinides, S. V., Ten Cate, H. & Wild, P. S. Sci Rep 12, 9761 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35697739
Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels. Cecon, E., Fernandois, D., Renault, N., Coelho, C. F. F., Wenzel, J., Bedart, C., Izabelle, C., Gallet, S., Le Poder, S., Klonjkowski, B., Schwaninger, M., Prevot, V., Dam, J. & Jockers, R. Cell Mol Life Sci 79, 361 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35697820
Complications of balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: Impact on the outcome. Wiedenroth, C. B., Deissner, H., Adameit, M. S. D., Kriechbaum, S. D., Ghofrani, H. A., Breithecker, A., Haas, M., Roller, F., Rolf, A., Hamm, C. W., Mayer, E., Guth, S. & Liebetrau, C. J Heart Lung Transplant (2022). https://www.ncbi.nlm.nih.gov/pubmed/35690560
Alkaline phosphatase and prognosis in patients with diabetes mellitus and ischemic heart disease. Ndrepepa, G., Holdenrieder, S., Xhepa, E., Cassese, S., Lahu, S., Kufner, S. & Kastrati, A. Clin Chim Acta 533, 1-7 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35690085
Beyond the 10-year horizon: Mitral valve repair solely with chordal replacement and annuloplasty. Lang, M., Vitanova, K., Voss, B., Feirer, N., Rheude, T., Krane, M., Gunther, T. & Lange, R. Ann Thorac Surg(2022). https://www.ncbi.nlm.nih.gov/pubmed/35690138
Human cardiac organoids to model COVID-19 cytokine storm induced cardiac injuries. Arhontoulis, D. C., Kerr, C. M., Richards, D., Tjen, K., Hyams, N., Jones, J. A., Deleon-Pennell, K., Menick, D., Brauninger, H., Lindner, D., Westermann, D. & Mei, Y. J Tissue Eng Regen Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35689600
The Transcription Factor EB (TFEB) Sensitizes the Heart to Chronic Pressure Overload. Wundersitz, S., Pablo Tortola, C., Schmidt, S., Oliveira Vidal, R., Kny, M., Hahn, A., Zanders, L., Katus, H. A., Sauer, S., Butter, C., Luft, F. C., Muller, O. J. & Fielitz, J. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35682624
Associations of the vasoactive peptides CT-proET-1 and MR-proADM with incident type 2 diabetes: results from the BiomarCaRE Consortium. Sujana, C., Salomaa, V., Kee, F., Seissler, J., Jousilahti, P., Neville, C., Then, C., Koenig, W., Kuulasmaa, K., Reinikainen, J., Blankenberg, S., Zeller, T., Herder, C., Mansmann, U., Peters, A., Thorand, B. & BiomarCa, R. E. C. Cardiovasc Diabetol 21, 99 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35681200
Practical Guidance for Diagnosing and Treating Iron Deficiency in Patients with Heart Failure: Why, Who and How? Sindone, A., Doehner, W., Manito, N., McDonagh, T., Cohen-Solal, A., Damy, T., Nunez, J., Pfister, O., van der Meer, P. & Comin-Colet, J. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35683366
Hypoxia Differentially Affects Healthy Men and Women During a Daytime Nap With a Dose-Response Relationship: a Randomized, Cross-Over Pilot Study. Riveros-Rivera, A., Penzel, T., Gunga, H. C., Opatz, O., Paul, F., Klug, L., Boschmann, M. & Mahler, A. Front Physiol 13, 899636 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35685284
Epoxyeicosatrienoic Acid and Prostanoid Crosstalk at the Receptor and Intracellular Signaling Levels to Maintain Vascular Tone. Malacarne, P. F., Bezzenberger, J., Lopez, M., Warwick, T., Muller, N., Brandes, R. P. & Rezende, F. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35682616
Real-Time Optical Mapping of Contracting Cardiac Tissues With GPU-Accelerated Numerical Motion Tracking. Lebert, J., Ravi, N., Kensah, G. & Christoph, J. Front Cardiovasc Med 9, 787627 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35686036
Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes. Jakobi, T., Gross, J., Cyganek, L. & Doroudgar, S. Front Cardiovasc Med 9, 844441 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35686037
Empagliflozin and serum potassium in heart failure: an analysis from EMPEROR-Pooled. Ferreira, J. P., Zannad, F., Butler, J., Filipattos, G., Ritter, I., Schuler, E., Kraus, B. J., Pocock, S. J., Anker, S. D. & Packer, M. Eur Heart J 43, 2984-2993 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35687107
SRF: a seriously responsible factor in cardiac development and disease. Deshpande, A., Shetty, P. M. V., Frey, N. & Rangrez, A. Y. J Biomed Sci 29, 38 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35681202
Comparison of PCWP and LVEDP Measurements in Patients with Severe Aortic Stenosis Undergoing TAVI-Same Same but Different? Boxhammer, E., Mirna, M., Baz, L., Alushi, B., Franz, M., Kretzschmar, D., Hoppe, U. C., Lauten, A. & Lichtenauer, M. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35683367
Neo to Neo2: A Tiny Detail With Considerable Impact. Kim, W. K. & Mollmann, H. JACC Cardiovasc Interv15, 1111-1112 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35680189
Clinician approach to cardiopulmonary exercise testing for exercise prescription in patients at risk of and with cardiovascular disease. D'Ascenzi, F., Cavigli, L., Pagliaro, A., Focardi, M., Valente, S., Cameli, M., Mandoli, G. E., Mueller, S., Dendale, P., Piepoli, M., Wilhelm, M., Halle, M., Bonifazi, M. & Hansen, D. Br J Sports Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35680397
Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background. van Paridon, P. C. S., Panova-Noeva, M., van Oerle, R., Schulz, A., Prochaska, J. H., Arnold, N., Schmidtmann, I., Beutel, M., Pfeiffer, N., Munzel, T., Lackner, K. J., Ten Cate, H., Wild, P. S. & Spronk, H. M. H. Thromb J 20, 32 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35676710
Finerenone Reduces Renal RORgammat gammadelta T Cells and Protects against Cardiorenal Damage. Luettges, K., Bode, M., Diemer, J. N., Schwanbeck, J., Wirth, E. K., Klopfleisch, R., Kappert, K., Thiele, A., Ritter, D., Foryst-Ludwig, A., Kolkhof, P., Wenzel, U. O. & Kintscher, U. Am J Nephrol, 1-13 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35675794
Cross-sectional analysis of the association of periodontitis with carotid intima media thickness and atherosclerotic plaque in the Hamburg City health study. Lamprecht, R., Rimmele, D. L., Schnabel, R. B., Heydecke, G., Seedorf, U., Walther, C., Mayer, C., Struppek, J., Borof, K., Behrendt, C. A., Cheng, B., Gerloff, C., Debus, S., Smeets, R., Beikler, T., Blankenberg, S., Zeller, T., Karakas, M., Thomalla, G. & Aarabi, G. J Periodontal Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35675038
Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. Klockner, I., Schutt, C., Gerhardt, T., Boettger, T. & Braun, T. Nat Commun 13, 3180 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35676269
Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium. Gencer, S., Doring, Y., Jansen, Y., Bayasgalan, S., Yan, Y., Bianchini, M., Cimen, I., Muller, M., Peters, L. J. F., Megens, R. T. A., von Hundelshausen, P., Duchene, J., Lemnitzer, P., Soehnlein, O., Weber, C. & van der Vorst, E. P. C. Basic Res Cardiol 117, 30 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35674847
Subtotal obstruction of the left coronary ostium by chronic neo-intimal ingrowth. Friedrich, A., Pasic, M. & Falk, V. Eur Heart J 43, 2816 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35673900
Comorbidities in heart failure with preserved ejection fraction. Deichl, A., Wachter, R. & Edelmann, F. Herz 47, 301-307 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35674774
Long-term effects of discontinuing renin-angiotensin system inhibitors in COVID-19. Theurl, F., Sappler, N., Rizas, K. D., Massberg, S., Bauer, A. & Schreinlechner, M. Respirology (2022). https://www.ncbi.nlm.nih.gov/pubmed/35672267
Extracellular Inflammasome Particles Are Released After Marathon Running and Induce Proinflammatory Effects in Endothelial Cells. Kogel, A., Fikenzer, S., Uhlmann, L., Opitz, L., Kneuer, J. M., Haeusler, K. G., Endres, M., Kratzsch, J., Schwarz, V., Werner, C., Kalwa, H., Gaul, S. & Laufs, U. Front Physiol13, 866938 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35669577
Pig models for Duchenne muscular dystrophy - from disease mechanisms to validation of new diagnostic and therapeutic concepts. Stirm, M., Fonteyne, L. M., Shashikadze, B., Stockl, J. B., Kurome, M., Kessler, B., Zakhartchenko, V., Kemter, E., Blum, H., Arnold, G. J., Matiasek, K., Wanke, R., Wurst, W., Nagashima, H., Knieling, F., Walter, M. C., Kupatt, C., Frohlich, T., Klymiuk, N., Blutke, A. et al. Neuromuscul Disord (2022). https://www.ncbi.nlm.nih.gov/pubmed/35659494
TAVI Under Pressure: Intra-balloon Pressure Profiles During Balloon-Expandable TAVR-First Data from a Feasibility Study. Noterdaeme, T., Marx, N., Theiss, H., Orban, M., Roden, D., Massberg, S. & Braun, D. J Cardiovasc Transl Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35668315
Expert proposal to characterize cardiac diseases with normal or preserved left ventricular ejection fraction and symptoms of heart failure by comprehensive echocardiography. Hagendorff, A., Helfen, A., Brandt, R., Altiok, E., Breithardt, O., Haghi, D., Knierim, J., Lavall, D., Merke, N., Sinning, C., Stobe, S., Tschope, C., Knebel, F. & Ewen, S. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35660948
Atrial fibrillation progression and the importance of early treatment for improving clinical outcomes. Gunawardene, M. A. & Willems, S. Europace 24, ii22-ii28 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35661866
Remnant cholesterol and atherosclerotic disease in high cardiovascular risk patients. Beyond LDL cholesterol and hypolipidemic treatment. Delialis, D., Georgiopoulos, G., Aivalioti, E., Mavraganis, G., Dimopoulou, A. M., Sianis, A., Aggelidakis, L., Patras, R., Petropoulos, I., Ioannou, S., Syrigou, R., Chatzidou, S., Kanakakis, I., Stellos, K. & Stamatelopoulos, K. Hellenic J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35667617
Management of in-stent restenosis. Alfonso, F., Coughlan, J. J., Giacoppo, D., Kastrati, A. & Byrne, R. A. EuroIntervention 18, e103-e123 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35656726
Atrial fibrillation and heart failure: novel insights into the chicken and egg dilemma. Pabel, S. & Sossalla, S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35653688
SUMOylation in peripheral tissues under low perfusion-related pathological states. Oliveira, F., Soares, E. S., Harms, C., Cimarosti, H. I. & Sordi, R. J Cell Biochem (2022). https://www.ncbi.nlm.nih.gov/pubmed/35652521
Prognostic markers of all-cause mortality in patients with atrial fibrillation: data from the prospective long-term registry of the German Atrial Fibrillation NETwork (AFNET): Authors' reply. Nabauer, M., Gerth, A., Wegscheider, K., Buchholz, A., Haeusler, K. G., Ravens, U., Sprenger, C., Tebbe, U., Kirchhof, P., Breithardt, G. & Steinbeck, G. Europace 24, 1872-1873 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35655121
Acute Decompensated Heart Failure in the Setting of Acute Coronary Syndrome. Harrington, J., Jones, W. S., Udell, J. A., Hannan, K., Bhatt, D. L., Anker, S. D., Petrie, M. C., Vedin, O., Butler, J. & Hernandez, A. F. JACC Heart Fail 10, 404-414 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35654525
Vascular aging in the young: New carotid stiffness centiles and association with general and abdominal obesity - The KIGGS cohort. Buschges, J., Schaffrath Rosario, A., Schienkiewitz, A., Konigstein, K., Sarganas, G., Schmidt-Trucksass, A. & Neuhauser, H. Atherosclerosis (2022). https://www.ncbi.nlm.nih.gov/pubmed/35654616
SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress. Tangos, M., Budde, H., Kolijn, D., Sieme, M., Zhazykbayeva, S., Lodi, M., Herwig, M., Gomori, K., Hassoun, R., Robinson, E. L., Meister, T. L., Jaquet, K., Kovacs, A., Mustroph, J., Evert, K., Babel, N., Fagyas, M., Lindner, D., Puschel, K., Westermann, D. et al. Int J Cardiol 362, 196-205 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35643215
Response to AJE-00301-2022 Invited Commentary "Mechanistic and biologically based models in epidemiology; a powerful underutilized tool" by Rafael Meza & Jihyoun Jeon. Simonetto, C., Heier, M., Peters, A., Kaiser, J. C. & Rospleszcz, S. Am J Epidemiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35650119
The impact of ultra-high-density mapping on long-term outcome after catheter ablation of ventricular tachycardia. Schleberger, R., Schwarzl, J. M., Moser, J., Nies, M., Holler, A., Munkler, P., Dinshaw, L., Jungen, C., Lemoine, M. D., Maury, P., Sacher, F., Martin, C. A., Wong, T., Estner, H. L., Jais, P., Willems, S., Eickholt, C. & Meyer, C. Sci Rep 12, 9139 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35650230
Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. Naeem, Z., Zukunft, S., Gunther, S., Liebner, S., Weigert, A., Hammock, B. D., Fromel, T. & Fleming, I. Pflugers Arch (2022). https://www.ncbi.nlm.nih.gov/pubmed/35648219
MicroRNAs as therapeutic targets in cardiovascular disease. Laggerbauer, B. & Engelhardt, S. J Clin Invest 132 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35642640
Left Atrial Volume Index and Outcome after Transcatheter Edge-to-edge Valve Repair for Secondary Mitral Regurgitation. Iliadis, C., Kalbacher, D., Lurz, P., Petrescu, A. M., Orban, M., Puscas, T., Lupi, L., Stazzoni, L., Pires-Morais, G., Koell, B., Besler, C., Ruf, T. F., Stolz, L., Tence, N., Adamo, M., Giannini, C., Guerreiro, C., Hellmich, M., Baldus, S., Schofer, N. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35642951
Lack of correlation between different congestion markers in acute decompensated heart failure. Haag, S., Jobs, A., Stiermaier, T., Fichera, C. F., Paitazoglou, C., Eitel, I., Desch, S. & Thiele, H. Clin Res Cardiol(2022). https://www.ncbi.nlm.nih.gov/pubmed/35648271
Multi-national survey on the methods, efficacy, and safety on the post-approval clinical use of pulsed field ablation (MANIFEST-PF). Ekanem, E., Reddy, V. Y., Schmidt, B., Reichlin, T., Neven, K., Metzner, A., Hansen, J., Blaauw, Y., Maury, P., Arentz, T., Sommer, P., Anic, A., Anselme, F., Boveda, S., Deneke, T., Willems, S., van der Voort, P., Tilz, R., Funasako, M., Scherr, D. et al. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/35647644
Heart failure with normal LVEF in BIOSTAT-CHF. Baumhove, L., Tromp, J., Figarska, S., van Essen, B. J., Anker, S. D., Dickstein, K., Cleland, J. G., Lang, C. C., Filippatos, G., Ng, L. L., Samani, N. J., Metra, M., van Veldhuisen, D. J., Lam, C. S. P., Voors, A. A. & van der Meer, P. Int J Cardiol 364, 85-90 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35649488
AFM-based nanoindentation indicates an impaired cortical stiffness in the AAV-PCSK9(DY) atherosclerosis mouse model. Achner, L., Klersy, T., Fels, B., Reinberger, T., Schmidt, C. X., Gross, N., Hille, S., Muller, O. J., Aherrahrou, Z., Kusche-Vihrog, K. & Raasch, W. Pflugers Arch 474, 993-1002 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35648220
Systolic or diastolic CT image acquisition for transcatheter aortic valve replacement - An outcome analysis. Steffen, J., Beckmann, M., Haum, M., Fischer, J., Andreae, D., Orban, M., Rizas, K., Braun, D., Orban, M., Curta, A., Hagl, C., Theiss, H. D., Mehilli, J., Massberg, S., Deseive, S. & Hausleiter, J. J Cardiovasc Comput Tomogr (2022). https://www.ncbi.nlm.nih.gov/pubmed/35637128
Association between a polygenic and family risk score on the prevalence and incidence of myocardial infarction in the KORA-F3 study. Schnitzer, F., Forer, L., Schonherr, S., Gieger, C., Grallert, H., Kronenberg, F., Peters, A. & Lamina, C. Atherosclerosis 352, 10-17 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35636145
Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance. Schlautmann, L. P., Lackmann, J. W., Altmuller, J., Dieterich, C., Boehm, V. & Gehring, N. H. Nucleic Acids Res 50, 5899-5918 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35640609
Adverse Cardiovascular Effects of Anti-tumor Therapies in Patients With Breast Cancer: A Single-center Cross-sectional Analysis. Rosenkaimer, S., Sieburg, T., Winter, L., Mavratzas, A., Hofmann, W. K., Hofheinz, R. D., Akin, I., Duerschmied, D. & Hohneck, A. Anticancer Res 42, 3075-3084 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35641278
Evaluation of a pneumatic tube system carrier prototype with fixing mechanism allowing for automated unloading. Martens, C. M., Schopfel, J., Bollmann, S., Hannemann, A., Zylla, S., Dahl, M. B., Gauss, F., Schedl, J., Nauck, M. & Petersmann, A. Clin Chem Lab Med 60, 1202-1210 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35635785
Tooth loss in periodontally treated patients: A registry- and observation-based analysis. Kocher, T., Holtfreter, B., Priess, H. W., Graetz, C., Jablonowski, L., Grabe, H. J., Volzke, H., Raedel, M. & Walter, M. H. J Clin Periodontol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35634709
Cerebral consequences of environmental noise exposure. Hahad, O., Bayo Jimenez, M. T., Kuntic, M., Frenis, K., Steven, S., Daiber, A. & Munzel, T. Environ Int 165, 107306 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35635962
Juli
Paper of the Month
3,5-T2-an Endogenous Thyroid Hormone Metabolite as Promising Lead Substance in Anti-Steatotic Drug Development? Sane, R., Wirth, E. K. & Kohrle, J. Metabolites 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35888706
Intravital calcium imaging in myeloid leukocytes identifies calcium frequency spectra as indicators of functional states. Mehari, F. T., Miller, M., Pick, R., Bader, A., Pekayvaz, K., Napoli, M., Uhl, B., Reichel, C. A., Sperandio, M., Walzog, B., Schulz, C., Massberg, S. & Stark, K. Sci Signal 15, eabe6909 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35881691
Edoxaban for stroke prevention in atrial fibrillation and age-adjusted predictors of clinical outcomes in routine clinical care. Kirchhof, P., Pecen, L., Bakhai, A., de Asmundis, C., de Groot, J. R., Deharo, J. C., Kelly, P., Levy, P., Lopez-de-Sa, E., Monteiro, P., Steffel, J., Waltenberger, J., Weiss, T. W., Laeis, P., Manu, M. C., Souza, J. & De Caterina, R. Eur Heart J Cardiovasc Pharmacother 9, 47-57 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35881467
Impact of ischaemic aetiology on the efficacy of intravenous ferric carboxymaltose in patients with iron deficiency and acute heart failure: insights from the AFFIRM-AHF trial. Metra, M., Jankowska, E. A., Pagnesi, M., Anker, S. D., Butler, J., Dorigotti, F., Fabien, V., Filippatos, G., Kirwan, B. A., Macdougall, I. C., Rosano, G., Ruschitzka, F., Tomasoni, D., van der Meer, P., Ponikowski, P. & Investigators, A.-A. Eur J Heart Fail 24, 1928-1939 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35869741
A cross-sectional analysis of post-acute COVID-19 symptoms. Perna, S., Abdulsattar, S., Alalwan, T. A., Zahid, M. N., Gasparri, C., Peroni, G., Faragli, A., La Porta, E., Ali Redha, A., Janahi, E. M. & Rondanelli, M. Ann Ig 34, 478-489 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35861720
Cardiac Macrophages and Their Effects on Arrhythmogenesis. Xia, R., Tomsits, P., Loy, S., Zhang, Z., Pauly, V., Schuttler, D. & Clauss, S. Front Physiol 13, 900094 (2022). www.ncbi.nlm.nih.gov/pubmed/35812333
Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp. Rosholm, K. R., Badone, B., Karatsiompani, S., Nagy, D., Seibertz, F., Voigt, N. & Bell, D. C. Front Mol Neurosci 15, 898717 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35813069
Health-Related Quality of Life following Surgery for Native and Prosthetic Valve Infective Endocarditis. Saha, S., Mladenova, R., Radner, C., Horke, K. M., Buech, J., Schnackenburg, P., Ali, A., Peterss, S., Juchem, G., Luehr, M., Hagl, C. & Joskowiak, D. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35806881
Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case Series. Baumeier, C., Aleshcheva, G., Harms, D., Gross, U., Hamm, C., Assmus, B., Westenfeld, R., Kelm, M., Rammos, S., Wenzel, P., Munzel, T., Elsasser, A., Gailani, M., Perings, C., Bourakkadi, A., Flesch, M., Kempf, T., Bauersachs, J., Escher, F. & Schultheiss, H. P. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35805941
Three-component carboacylation of alkenes via cooperative nickelaphotoredox catalysis. Wang, D. & Ackermann, L. Chem Sci 13, 7256-7263 (2022). www.ncbi.nlm.nih.gov/pubmed/35799820
The Seasonal Fluctuation of Fatigue in Multiple Sclerosis. Grothe, M., Gross, S., Susse, M., Strauss, S. & Penner, I. K. Front Neurol 13, 900792 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35785351
A Method to Combine Neurofilament Light Measurements From Blood Serum and Plasma in Clinical and Population-Based Studies. Rubsamen, N., Willemse, E. A. J., Leppert, D., Wiendl, H., Nauck, M., Karch, A., Kuhle, J. & Berger, K. Front Neurol 13, 894119 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35775045
Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors. Mann, A. M., Schafer, W., Adriouch, S., Borner, K., Grimm, D., Braren, I. & Koch-Nolte, F. Methods Mol Biol 2510, 129-144 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35776323
Association of White Blood Cell Count With Clinical Outcome Independent of Treatment With Alteplase in Acute Ischemic Stroke. Barow, E., Quandt, F., Cheng, B., Gelderblom, M., Jensen, M., Konigsberg, A., Boutitie, F., Nighoghossian, N., Ebinger, M., Endres, M., Fiebach, J. B., Thijs, V., Lemmens, R., Muir, K. W., Pedraza, S., Simonsen, C. Z., Gerloff, C. & Thomalla, G. Front Neurol 13, 877367 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35769368
Impact of open-irrigated radiofrequency catheter with contact force measurement on the efficacy and safety of atrial fibrillation ablation: a single-center direct comparison. Schlogl, S., Schlogl, K. S., Bengel, P., Bergau, L., Haarmann, H., Rasenack, E., Hasenfuss, G. & Zabel, M. J Interv Card Electrophysiol 65, 685-693 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35907108
The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics. Schons, M., Pilgram, L., Reese, J. P., Stecher, M., Anton, G., Appel, K. S., Bahmer, T., Bartschke, A., Bellinghausen, C., Bernemann, I., Brechtel, M., Brinkmann, F., Brunn, C., Dhillon, C., Fiessler, C., Geisler, R., Hamelmann, E., Hansch, S., Hanses, F., Hanss, S. et al. Eur J Epidemiol, 1-22 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35904671
TRPC1 channels regulate the activation of pancreatic stellate cells through ERK1/2 and SMAD2 pathways and perpetuate their pressure-mediated activation. Radoslavova, S., Fels, B., Petho, Z., Gruner, M., Ruck, T., Meuth, S. G., Folcher, A., Prevarskaya, N., Schwab, A. & Ouadid-Ahidouch, H. Cell Calcium 106, 102621 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35905654
Outcome after surgical embolectomy for acute pulmonary embolism. Panholzer, B., Gravert, H., Borzikowsky, C., Huenges, K., Schoettler, J., Schoeneich, F., Attmann, T., Haneya, A., Frank, D., Cremer, J. & Grothusen, C. J Cardiovasc Med (Hagerstown) 23, 519-523 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35905002
Dual ProGlide versus ProGlide and FemoSeal for vascular access haemostasis after transcatheter aortic valve implantation. Gmeiner, J. M. D., Linnemann, M., Steffen, J., Scherer, C., Orban, M., Theiss, H., Mehilli, J., Sadoni, S., Peterss, S., Joskowiak, D., Hagl, C., Tsilimparis, N., Curta, A., Maurus, S., Doldi, P. M., Low, K., Haum, M., Roden, D., Hausleiter, J., Massberg, S. et al. EuroIntervention 18, 812-819 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35903846
Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage. Avery, E. G., Bartolomaeus, H., Rauch, A., Chen, C. Y., N'Diaye, G., Lober, U., Bartolomaeus, T. U. P., Fritsche-Guenther, R., Rodrigues, A. F., Yarritu, A., Zhong, C., Fei, L., Tsvetkov, D., Todiras, M., Park, J. K., Marko, L., Maifeld, A., Patzak, A., Bader, M., Kempa, S. et al. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35904261
Remote Patient Management May Reduce All-Cause Mortality in Patients With Heart-Failure and Renal Impairment. Naik, M. G., Budde, K., Koehler, K., Vettorazzi, E., Pigorsch, M., Arkossy, O., Stuard, S., Duettmann, W., Koehler, F. & Winkler, S. Front Med (Lausanne) 9, 917466 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35899216
Early coronary angiography in patients after out-of-hospital cardiac arrest without ST-segment elevation: Meta-analysis of randomized controlled trials. Freund, A., van Royen, N., Kern, K. B., Jobs, A., Thiele, H., Lemkes, J. S., Desch, S., Tomahawk, P. & investigators, C. Catheter Cardiovasc Interv (2022). https://www.ncbi.nlm.nih.gov/pubmed/35900214
From novel discovery tools and biomarkers to precision medicine - basic cardiovascular science highlights of 2021/2022. Evans, P. C., Davidson, S. M., Wojta, J., Back, M., Bollini, S., Brittan, M., Catapano, A. L., Chaudhry, B., Cluitmans, M., Gnecchi, M., Guzik, T. J., Hoefer, I., Madonna, R., Monteiro, J. P., Morawietz, H., Osto, E., Padro, T., Sluimer, J. C., Tocchetti, C. G., Van der Heiden, K. et al. Cardiovasc Res(2022). https://www.ncbi.nlm.nih.gov/pubmed/35899362
A framework of deep learning networks provides expert-level accuracy for the detection and prognostication of pulmonary arterial hypertension. Diller, G. P., Benesch Vidal, M. L., Kempny, A., Kubota, K., Li, W., Dimopoulos, K., Arvanitaki, A., Lammers, A. E., Wort, S. J., Baumgartner, H., Orwat, S. & Gatzoulis, M. A. Eur Heart J Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35900292
Patiromer for the management of hyperkalemia in heart failure with reduced ejection fraction: the DIAMOND trial. Butler, J., Anker, S. D., Lund, L. H., Coats, A. J. S., Filippatos, G., Siddiqi, T. J., Friede, T., Fabien, V., Kosiborod, M., Metra, M., Pina, I. L., Pinto, F., Rossignol, P., van der Meer, P., Bahit, C., Belohlavek, J., Bohm, M., Brugts, J. J., Cleland, J. G., Ezekowitz, J. et al. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35900838
Calcium-Controlled Reactive Oxygen Species Afterburner Perpetuates Endothelial Damage After Radiation Therapy. Brandes, R. P. & Wittig, I. Arterioscler Thromb Vasc Biol 42, 1137-1138 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35899615
Epigenetic mechanism of L-type calcium channel beta-subunit downregulation in short QT human induced pluripotent stem cell-derived cardiomyocytes with CACNB2 mutation. Zhong, R., Zhang, F., Yang, Z., Li, Y., Xu, Q., Lan, H., Cyganek, L., El-Battrawy, I., Zhou, X., Akin, I. & Borggrefe, M. Europace 24, 2028-2036 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35894107
Case-Fatality and Temporal Trends in Patients with Psoriasis and End-Stage Renal Disease. Wild, J., Keller, K., Karbach, S., Weinmann-Menke, J., Munzel, T. & Hobohm, L. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35893416
In Prostate Cancer Cells Cytokines Are Early Responders to Gravitational Changes Occurring in Parabolic Flights. Schulz, H., Dietrichs, D., Wehland, M., Corydon, T. J., Hemmersbach, R., Liemersdorf, C., Melnik, D., Hubner, N., Saar, K., Infanger, M. & Grimm, D. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35887223
Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference. Schnabel, R. B., Marinelli, E. A., Arbelo, E., Boriani, G., Boveda, S., Buckley, C. M., Camm, A. J., Casadei, B., Chua, W., Dagres, N., de Melis, M., Desteghe, L., Diederichsen, S. Z., Duncker, D., Eckardt, L., Eisert, C., Engler, D., Fabritz, L., Freedman, B., Gillet, L. et al. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/35894842
Ex-vivo evaluation of the Ozaki procedure in comparison with the native aortic valve and prosthetic valves. Saisho, H., Scharfschwerdt, M., Schaller, T., Sadat, N., Aboud, A., Ensminger, S. & Fujita, B. Interact Cardiovasc Thorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35895002
Baseline Splenic Volume Outweighs Immuno-Modulated Size Changes with Regard to Survival Outcome in Patients with Hepatocellular Carcinoma under Immunotherapy. Muller, L., Gairing, S. J., Kloeckner, R., Foerster, F., Weinmann, A., Mittler, J., Stoehr, F., Emrich, T., Duber, C., Galle, P. R. & Hahn, F. Cancers (Basel) 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35892833
Weight loss-induced improvement of body weight and insulin sensitivity is not amplified by a subsequent 12-month weight maintenance intervention but is predicted by adaption of adipose atrial natriuretic peptide system: 48-month results of a randomized controlled trial. Li, L., Soll, D., Leupelt, V., Spranger, J. & Mai, K. BMC Med 20, 238 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35897098
Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study. Lange, T., Backhaus, S. J., Beuthner, B. E., Topci, R., Rigorth, K. R., Kowallick, J. T., Evertz, R., Schnelle, M., Ravassa, S., Diez, J., Toischer, K., Seidler, T., Puls, M., Hasenfuss, G. & Schuster, A. J Cardiovasc Magn Reson 24, 45 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35897100
Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort. Konig, E., Rainer, J., Hernandes, V. V., Paglia, G., Del Greco, M. F., Bottigliengo, D., Yin, X., Chan, L. S., Teumer, A., Pramstaller, P. P., Locke, A. E. & Fuchsberger, C. Metabolites 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35888728
The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm. Kirchhof, L., Fouani, Y., Knau, A., Aslan, G. S., Heumuller, A. W., Wittig, I., Muller-McNicoll, M., Dimmeler, S. & Jae, N. Noncoding RNA 8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35893232
Simultaneous LC-ESI-MS/MS Quantification of Levosimendan and Its Metabolites for Therapeutic Drug Monitoring of Cardiac Surgery Patients. Kipka, H., Tomasi, R., Hubner, M., Liebchen, U., Hagl, C., Wanner, K. T., Mannell, H. & Hofner, G. Pharmaceutics 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35890349
Anosmia Testing as Early Detection of SARS-CoV-2 Positivity; A Prospective Study under Screening Conditions. Jungbauer, F., Gerhards, C., Thiaucourt, M., Behnes, M., Rotter, N., Schell, A., Haselmann, V., Neumaier, M. & Kittel, M. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35888058
Association between Usual Dietary Intake of Food Groups and DNA Methylation and Effect Modification by Metabotype in the KORA FF4 Cohort. Hellbach, F., Baumeister, S. E., Wilson, R., Wawro, N., Dahal, C., Freuer, D., Hauner, H., Peters, A., Winkelmann, J., Schwettmann, L., Rathmann, W., Kronenberg, F., Koenig, W., Meisinger, C., Waldenberger, M. & Linseisen, J. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35888152
Thrombelastography Compared with Multiple Impedance Aggregometry to Assess High On-Clopidogrel Reactivity in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention. Gjermeni, D., Vetter, H., Szabo, S., Anfang, V., Leggewie, S., Hesselbarth, D., Duerschmied, D., Trenk, D. & Olivier, C. B. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35888001
APOE epsilon4 in Depression-Associated Memory Impairment-Evidence from Genetic and MicroRNA Analyses. Bonk, S., Kirchner, K., Ameling, S., Garvert, L., Volzke, H., Nauck, M., Volker, U., Grabe, H. J. & Van der Auwera, S. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35884866
Fantastic AAV Gene Therapy Vectors and How to Find Them-Random Diversification, Rational Design and Machine Learning. Becker, J., Fakhiri, J. & Grimm, D. Pathogens 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35890005
Edoxaban for stroke prevention in atrial fibrillation and age-adjusted predictors of clinical outcomes in routine clinical care. Kirchhof, P., Pecen, L., Bakhai, A., de Asmundis, C., de Groot, J. R., Deharo, J. C., Kelly, P., Levy, P., Lopez-de-Sa, E., Monteiro, P., Steffel, J., Waltenberger, J., Weiss, T. W., Laeis, P., Manu, M. C., Souza, J. & De Caterina, R. Eur Heart J Cardiovasc Pharmacother (2022). https://www.ncbi.nlm.nih.gov/pubmed/35881467
TAVR for All? The Surgical Perspective. Zhang, X., Puehler, T., Frank, D., Sathananthan, J., Sellers, S., Meier, D., Both, M., Blanke, P., Seoudy, H., Saad, M., Muller, O. J., Sondergaard, L. & Lutter, G. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35877585
Peak Oxygen Uptake on Cardiopulmonary Exercise Test Is a Predictor for Severe Arrhythmic Events during Three-Year Follow-Up in Patients with Complex Congenital Heart Disease. von Sanden, F., Ptushkina, S., Hock, J., Fritz, C., Horer, J., Hessling, G., Ewert, P., Hager, A. & Wolf, C. M. J Cardiovasc Dev Dis 9(2022). https://www.ncbi.nlm.nih.gov/pubmed/35877577
Pathogenic Variants in Cardiomyopathy Disorder Genes Underlie Pediatric Myocarditis-Further Impact of Heterozygous Immune Disorder Gene Variants? Seidel, F., Laser, K. T., Klingel, K., Dartsch, J., Theisen, S., Pickardt, T., Holtgrewe, M., Gartner, A., Berger, F., Beule, D., Milting, H., Schubert, S., Klaassen, S. & Kuhnisch, J. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35877578
Evidence for correlations between BMI-associated SNPs and circRNAs. Rajcsanyi, L. S., Diebels, I., Pastoors, L., Kanber, D., Peters, T., Volckmar, A. L., Zheng, Y., Grosse, M., Dieterich, C., Hebebrand, J., Kaiser, F. J., Horsthemke, B. & Hinney, A. Sci Rep 12, 12643 (2022). www.ncbi.nlm.nih.gov/pubmed/35879369
Left Ventricular Noncompaction in Children: The Role of Genetics, Morphology, and Function for Outcome. Klaassen, S., Kuhnisch, J., Schultze-Berndt, A. & Seidel, F. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35877568
Cardiovascular Safety Reporting in Contemporary Breast Cancer Clinical Trials. Hamid, A., Anker, M. S., Ruckdeschel, J. C., Khan, M. S., Tharwani, A., Oshunbade, A. A., Kipchumba, R. K., Thigpen, S. C., Anker, S. D., Fonarow, G. C., Hall, M. E. & Butler, J. J Am Heart Assoc 11, e025206 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35876414
Long COVID and the cardiovascular system - elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: A joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial & Pericardial Diseases. Gyongyosi, M., Alcaide, P., Asselbergs, F. W., Brundel, B., Camici, G. G., da Costa Martins, P., Ferdinandy, P., Fontana, M., Girao, H., Gnecchi, M., Gollmann-Tepekoylu, C., Kleinbongard, P., Krieg, T., Madonna, R., Paillard, M., Pantazis, A., Perrino, C., Pesce, M., Schiattarella, G. G., Sluijter, J. P. G. et al. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35875883
Cerebral small vessel disease burden and cognitive and functional outcomes after stroke: A multicenter prospective cohort study. Georgakis, M. K., Fang, R., During, M., Wollenweber, F. A., Bode, F. J., Stosser, S., Kindlein, C., Hermann, P., Liman, T. G., Nolte, C. H., Kerti, L., Ikenberg, B., Bernkopf, K., Poppert, H., Glanz, W., Perosa, V., Janowitz, D., Wagner, M., Neumann, K., Speck, O. et al. Alzheimers Dement(2022). https://www.ncbi.nlm.nih.gov/pubmed/35876563
Telemedicine acceptance and efficacy in the context of preventive cardiology interventions: A systematic review. Gass, F., Halle, M. & Mueller, S. Digit Health 8, 20552076221114186 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35874861
Severity, predictors and clinical correlates of post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study. Bahmer, T., Borzikowsky, C., Lieb, W., Horn, A., Krist, L., Fricke, J., Scheibenbogen, C., Rabe, K. F., Maetzler, W., Maetzler, C., Laudien, M., Frank, D., Ballhausen, S., Hermes, A., Muljukov, O., Haeusler, K. G., Mokhtari, N. E. E., Witzenrath, M., Vehreschild, J. J., Krefting, D. et al. EClinicalMedicine 51, 101549 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35875815
SGLT2 Inhibitors: From Antihyperglycemic Agents to All-Around Heart Failure Therapy. Anker, S. D., Usman, M. S. & Butler, J. Circulation 146, 299-302 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35877834
Impact of medication adherence on the efficacy of Baroreflex activation therapy. Schafer, A. C., Muller, D., Born, E., Muhlhaus, M., Luders, S., Wallbach, M. & Koziolek, M. J. J Clin Hypertens (Greenwich) 24, 1051-1058 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35870124
Aortic valve neocuspidization using autologous pericardium compared to surgical aortic valve replacement. Boehm, J., Vitanova, K., Prinzing, A., Krane, M. & Lange, R. J Card Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35870166
Effects of BNP and Sacubitrilat/Valsartan on Atrial Functional Reserve and Arrhythmogenesis in Human Myocardium. Primessnig, U., Deissler, P. M., Wakula, P., Tran, K. L., Hohendanner, F., von Lewinski, D., Blaschke, F., Knosalla, C., Falk, V., Pieske, B., Grubitzsch, H. & Heinzel, F. R. Front Cardiovasc Med 9, 859014 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35865376
CT-Based Analysis of Left Ventricular Hemodynamics Using Statistical Shape Modeling and Computational Fluid Dynamics. Goubergrits, L., Vellguth, K., Obermeier, L., Schlief, A., Tautz, L., Bruening, J., Lamecker, H., Szengel, A., Nemchyna, O., Knosalla, C., Kuehne, T. & Solowjowa, N. Front Cardiovasc Med 9, 901902 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35865389
Mineralocorticoid receptor-antagonism prevents COVID-19-dependent glycocalyx damage. Fels, B., Acharya, S., Vahldieck, C., Graf, T., Kading, N., Rupp, J. & Kusche-Vihrog, K. Pflugers Arch, 1-8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35867189
Minimising multi-centre radiomics variability through image normalisation: a pilot study. Campello, V. M., Martin-Isla, C., Izquierdo, C., Guala, A., Palomares, J. F. R., Vilades, D., Descalzo, M. L., Karakas, M., Cavus, E., Raisi-Estabragh, Z., Petersen, S. E., Escalera, S., Segui, S. & Lekadir, K. Sci Rep 12, 12532 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35869125
Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system. Peischard, S., Moller, M., Disse, P., Ho, H. T., Verkerk, A. O., Strutz-Seebohm, N., Budde, T., Meuth, S. G., Schweizer, P. A., Morris, S., Mucher, L., Eisner, V., Thomas, D., Klingel, K., Busch, K. & Seebohm, G. Cell Mol Life Sci 79, 440 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35864219
Hemodynamic stress-induced cardiac remodelling is not modulated by ablation of phosphodiesterase 4D interacting protein. Mohamed, B. A., Elkenani, M., Mobarak, S., Marques Rodrigues, D., Annamalai, K., Schnelle, M., Bader, M., Hasenfuss, G. & Toischer, K. J Cell Mol Med 26, 4440-4452 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35860864
Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation. Meyer-Lindemann, U., Mauersberger, C., Schmidt, A. C., Moggio, A., Hinterdobler, J., Li, X., Khangholi, D., Hettwer, J., Grasser, C., Dutsch, A., Schunkert, H., Kessler, T. & Sager, H. B. Front Immunol 13, 898690 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35860249
Restoration of Cardiomyogenesis in Aged Mouse Hearts by Voluntary Exercise. Lerchenmuller, C., Vujic, A., Mittag, S., Wang, A., Rabolli, C. P., Hess, C., Betge, F., Rangrez, A. Y., Chaklader, M., Guillermier, C., Gyngard, F., Roh, J. D., Li, H., Steinhauser, M. L., Frey, N., Rothermel, B., Dieterich, C., Rosenzweig, A. & Lee, R. T. Circulation 146, 412-426 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35862076
Origin and function of activated fibroblast states during zebrafish heart regeneration. Hu, B., Lelek, S., Spanjaard, B., El-Sammak, H., Simoes, M. G., Mintcheva, J., Aliee, H., Schafer, R., Meyer, A. M., Theis, F., Stainier, D. Y. R., Panakova, D. & Junker, J. P. Nat Genet 54, 1227-1237 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35864193
Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles. Hosen, M. R., Goody, P. R., Zietzer, A., Xiang, X., Niepmann, S. T., Sedaghat, A., Tiyerili, V., Chennupati, R., Moore, J. B. t., Boon, R. A., Uchida, S., Sinning, J. M., Zimmer, S., Latz, E., Werner, N., Nickenig, G. & Jansen, F. Circulation 146, 1836-1854 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35862223
Presenting Pattern of Atrial Fibrillation and Outcomes of Early Rhythm Control Therapy. Goette, A., Borof, K., Breithardt, G., Camm, A. J., Crijns, H., Kuck, K. H., Wegscheider, K., Kirchhof, P. & Investigators, E.-A. J Am Coll Cardiol 80, 283-295 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35863844
Autoimmunity to Sphingosine-1-Phosphate-Receptors in Systemic Sclerosis and Pulmonary Arterial Hypertension. Gluschke, H., Siegert, E., Minich, W. B., Hackler, J., Riemekasten, G., Kuebler, W. M., Simmons, S. & Schomburg, L. Front Immunol 13, 935787 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35860272
Active multi-task learning with uncertainty weighted loss for coronary calcium scoring. Follmer, B., Biavati, F., Wald, C., Stober, S., Ma, J., Dewey, M. & Samek, W. Med Phys (2022). https://www.ncbi.nlm.nih.gov/pubmed/35861655
Telomere Shortening in Hypertensive Heart Disease Depends on Oxidative DNA Damage and Predicts Impaired Recovery of Cardiac Function in Heart Failure. Brandt, M., Dorschmann, H., Khraisat, S., Knopp, T., Ringen, J., Kalinovic, S., Garlapati, V., Siemer, S., Molitor, M., Gobel, S., Stauber, R., Helena Karbach, S., Munzel, T., Daiber, A. & Wenzel, P. Hypertension, 101161HYPERTENSIONAHA12118935 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35862118
Analysis of epidemiological association patterns of serum thyrotropin by combining random forests and Bayesian networks. Becker, A. K., Ittermann, T., Dorr, M., Felix, S. B., Nauck, M., Teumer, A., Volker, U., Volzke, H., Kaderali, L. & Nath, N. PLoS One 17, e0271610 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35862421
Mosaic loss of Y chromosome during aging. Zeiher, A. & Braun, T. Science 377, 266-267 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35857599
Impaired AMP-Activated Protein Kinase Signaling in Heart Failure With Preserved Ejection Fraction-Associated Atrial Fibrillation. Tong, D., Schiattarella, G. G., Jiang, N., Daou, D., Luo, Y., Link, M. S., Lavandero, S., Gillette, T. G. & Hill, J. A. Circulation 146, 73-76 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35858165
Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome: the dal-GenE trial. Tardif, J. C., Pfeffer, M. A., Kouz, S., Koenig, W., Maggioni, A. P., McMurray, J. J. V., Mooser, V., Waters, D. D., Gregoire, J. C., L'Allier, P. L., Jukema, W. J., White, H. D., Heinonen, T., Black, D. M., Laghrissi-Thode, F., Levesque, S., Guertin, M. C., Dube, M. P. & dal-Gen, E. I. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35856777
Spacemake: processing and analysis of large-scale spatial transcriptomics data. Sztanka-Toth, T. R., Jens, M., Karaiskos, N. & Rajewsky, N. Gigascience 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35852420
The Spectrum of Central Nervous System Involvement in Whipple's Disease. Mecklenburg, J., Moos, V., Moter, A., Siebert, E., Nave, A. H., Schneider, T., Ruprecht, K. & Euskirchen, P. Eur J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35852414
Particular Challenges in the Use of Pulmonary Vasodilating Therapy for Patients with Pulmonary Hypertension Secondary to Left Heart Diseases. Dandel, M. & Hetzer, R. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35853842
Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Ralpha. Cai, Z., Tian, S., Klein, T., Tu, L., Geenen, L. W., Koudstaal, T., van den Bosch, A. E., de Rijke, Y. B., Reiss, I. K. M., Boersma, E., van der Ley, C., Van Faassen, M., Kema, I., Duncker, D. J., Boomars, K. A., Tran-Lundmark, K., Guignabert, C. & Merkus, D. Sci Rep 12, 12326 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35853948
Artificial intelligence fully automated myocardial strain quantification for risk stratification following acute myocardial infarction. Backhaus, S. J., Aldehayat, H., Kowallick, J. T., Evertz, R., Lange, T., Kutty, S., Bigalke, B., Gutberlet, M., Hasenfuss, G., Thiele, H., Stiermaier, T., Eitel, I. & Schuster, A. Sci Rep 12, 12220 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35851282
How COVID-19 affects microvessels in the brain. Wenzel, J. & Schwaninger, M. Brain 145, 2242-2244 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35848856
Bestform-F - Best Function of Range of Motion: A Feasibility Study of a Multimodal Exercise Training Program for Older Adults in Retirement Homes. Schaller, N., Krusemark, H., Mende, E., Weiss, M., Spanier, B., Zelger, O., Bischof, J., Haller, B., Halle, M. & Siegrist, M. Clin Interv Aging 17, 1069-1080 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35846178
CDK4/6 blockade provides an alternative approach for treatment of mismatch-repair deficient tumors. Salewski, I., Henne, J., Engster, L., Krone, P., Schneider, B., Redwanz, C., Lemcke, H., Henze, L., Junghanss, C. & Maletzki, C. Oncoimmunology 11, 2094583 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35845723
Systemic gene therapy with thymosin beta4 alleviates glomerular injury in mice. Mason, W. J., Jafree, D. J., Pomeranz, G., Kolatsi-Joannou, M., Rottner, A. K., Pacheco, S., Moulding, D. A., Wolf, A., Kupatt, C., Peppiatt-Wildman, C., Papakrivopoulou, E., Riley, P. R., Long, D. A. & Vasilopoulou, E. Sci Rep 12, 12172 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35842494
Transcatheter Mitral Valve Repair in Patients With Atrial Functional Mitral Regurgitation. Doldi, P., Stolz, L., Orban, M., Karam, N., Praz, F., Kalbacher, D., Lubos, E., Braun, D., Adamo, M., Giannini, C., Melica, B., Nabauer, M., Higuchi, S., Wild, M., Neuss, M., Butter, C., Kassar, M., Petrescu, A., Pfister, R., Iliadis, C. et al. JACC Cardiovasc Imaging (2022). https://www.ncbi.nlm.nih.gov/pubmed/35842361
Peak O2 -pulse predicts exercise training-induced changes in peak VO2 in heart failure with preserved ejection fraction. Mueller, S., Haller, B., Feuerstein, A., Winzer, E. B., Beckers, P., Haykowsky, M. J., Gevaert, A. B., Hommel, J., Azevedo, L. F., Duvinage, A., Esefeld, K., Fegers-Wustrow, I., Christle, J. W., Pieske-Kraigher, E., Belyavskiy, E., Morris, D. A., Kropf, M., Aravind-Kumar, R., Edelmann, F., Linke, A. et al.ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35840541
Fast acquisition of left and right ventricular function parameters applying cardiovascular magnetic resonance in clinical routine - validation of a 2-shot compressed sensing cine sequence. Groschel, J., Ammann, C., Zange, L., Viezzer, D., Forman, C., Schmidt, M., Blaszczyk, E. & Schulz-Menger, J. Scand Cardiovasc J 56, 266-275 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35836407
Response to the clinical commentary 'Telemedical monitoring by an implanted loop recorder: gateway to personalized medicine? Results of the SMART-MI study'. Rizas, K. D., Kaab, S., Massberg, S. & Bauer, A. Cardiovasc Res 118, e81 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35834784
Non-monotonous dose response function of the termination of spiral wave chaos. Lilienkamp, T., Parlitz, U. & Luther, S. Sci Rep 12, 12043 (2022). www.ncbi.nlm.nih.gov/pubmed/35835979
Eligibility for early rhythm control in patients with atrial fibrillation in the UK Biobank. Kany, S., Cardoso, V. R., Bravo, L., Williams, J. A., Schnabel, R., Fabritz, L., Gkoutos, G. V. & Kirchhof, P. Heart (2022). https://www.ncbi.nlm.nih.gov/pubmed/35835543
Spatial correction improves accuracy of catheter positioning during ablation of premature ventricular contractions: differences between ventricular outflow tracts and other localizations. Nies, M., Schleberger, R., Dinshaw, L., Klatt, N., Muenkler, P., Jungen, C., Rottner, L., Lemoine, M. D., Reissmann, B., Rillig, A., Metzner, A., Kirchhof, P. & Meyer, C. BMC Cardiovasc Disord 22, 312 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35831801
Standardized annotation of translated open reading frames. Mudge, J. M., Ruiz-Orera, J., Prensner, J. R., Brunet, M. A., Calvet, F., Jungreis, I., Gonzalez, J. M., Magrane, M., Martinez, T. F., Schulz, J. F., Yang, Y. T., Alba, M. M., Aspden, J. L., Baranov, P. V., Bazzini, A. A., Bruford, E., Martin, M. J., Calviello, L., Carvunis, A. R., Chen, J. et al. Nat Biotechnol 40, 994-999 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35831657
UFO procedure: Two small surgical details. Wert, L. & Pasic, M. J Card Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35819132
Pathophysiological insights with relevant impact on the prognostic assessment and clinical management of patients with pulmonary arterial hypertension. Dandel, M. J Physiol 600, 3633-3634 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35818117
Protein O-GlcNAcylation in cardiovascular diseases. Wang, H. F., Wang, Y. X., Zhou, Y. P., Wei, Y. P., Yan, Y., Zhang, Z. J. & Jing, Z. C. Acta Pharmacol Sin (2022). https://www.ncbi.nlm.nih.gov/pubmed/35817809
Reduction of contrast agent volume utilization for cardiac catheterization in current clinical practice. Stocker, T. J., Massberg, S. & Hausleiter, J. Int J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35817203
[Implantation of mechanical circulatory support systems and heart transplantation in patients with end-stage heart failure : Consensus paper of the DGK, DGTHG]. Schulze, P. C., Barten, M. J., Boeken, U., Farber, G., Hagl, C. M., Jung, C., Leistner, D., Potapov, E., Bauersachs, J., Raake, P., Reiss, N., Saeed, D., Schibilsky, D., Stork, S., Veltmann, C., Rieth, A. J. & Gummert, J. Med Klin Intensivmed Notfmed(2022). https://www.ncbi.nlm.nih.gov/pubmed/35816214
Nox4 promotes endothelial differentiation through chromatin remodeling. Hahner, F., Moll, F., Warwick, T., Hebchen, D. M., Buchmann, G. K., Epah, J., Abplanalp, W., Schader, T., Gunther, S., Gilsbach, R., Brandes, R. P. & Schroder, K. Redox Biol 55, 102381 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35810713
Role of Gpnmb in atherosclerosis of female mice. Nickl, B., Qadri, F. & Bader, M. Biochem Biophys Res Commun 621, 20-24 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35809343
The arch remodelling stent for DeBakey I acute aortic dissection: experience with 100 implantations. Montagner, M., Kofler, M., Seeber, F., Pitts, L., Starck, C., Sundermann, S. H., Kurz, S., Grubitzsch, H., Falk, V. & Kempfert, J. Eur J Cardiothorac Surg 62 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35809065
VARS2 Depletion Leads to Activation of the Integrated Stress Response and Disruptions in Mitochondrial Fatty Acid Oxidation. Kayvanpour, E., Wisdom, M., Lackner, M. K., Sedaghat-Hamedani, F., Boeckel, J. N., Muller, M., Eghbalian, R., Dudek, J., Doroudgar, S., Maack, C., Frey, N. & Meder, B. Int J Mol Sci23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35806332
Quantification of right atrial fibrosis by cardiac magnetic resonance: verification of the method to standardize thresholds. Gunturiz-Beltran, C., Borras, R., Alarcon, F., Garre, P., Ventura, R., Benito, E. M., Caixal, G., Althoff, T. F., Maria Tolosana, J., Arbelo, E., Roca, I., Prat-Gonzalez, S., Perea, R. J., Brugada, J., Sitges, M., Guasch, E. & Mont, L. Rev Esp Cardiol (Engl Ed) (2022). https://www.ncbi.nlm.nih.gov/pubmed/35809892
Restenosis after Coronary Stent Implantation: Cellular Mechanisms and Potential of Endothelial Progenitor Cells (A Short Guide for the Interventional Cardiologist). Gori, T. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35805178
Improved Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pacemaker Cells Using Novel Differentiation Protocols. Darche, F. F., Ullrich, N. D., Huang, Z., Koenen, M., Rivinius, R., Frey, N. & Schweizer, P. A. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35806319
miR-29c Increases Protein Synthesis in Skeletal Muscle Independently of AKT/mTOR. Alves, P. K. N., Cruz, A., Silva, W. J., Labeit, S. & Moriscot, A. S. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35806204
Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1. Rot, A., Gutjahr, J. C., Biswas, A., Aslani, M., Hub, E., Thiriot, A., von Andrian, U. H., Megens, R. T. A., Weber, C. & Duchene, J. Cell Stem Cell 29, 1013-1015 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35803222
Surgical explantation of failed transcatheter heart valves: indications and results. Muensterer, A., Puluca, N., Ruge, H., Vitanova, K. & Lange, R. Heart Vessels 37, 2083-2092 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35802181
The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins alpha9beta1 and alpha4beta1. Morris, G. E., Denniff, M. J., Karamanavi, E., Andrews, S. A., Kostogrys, R. B., Bountziouka, V., Ghaderi-Najafabadi, M., Shamkhi, N., McConnell, G., Kaiser, M. A., Carleton, L., Schofield, C., Kessler, T., Rainbow, R. D., Samani, N. J. & Webb, T. R. Br J Pharmacol 179, 4958-4973 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35802072
SVEP1 regulates GPCR-mediated vasoconstriction via integrin alpha9beta1 and alpha4beta1. Morris, G. E., Denniff, M. J., Karamanavi, E., Andrews, S. A., Kostogrys, R. B., Bountziouka, V., Ghaderi-Najafabadi, M., Shamkhi, N., McConnell, G., Kaiser, M. A., Carleton, L., Schofield, C., Kessler, T., Rainbow, R. D., Samani, N. J. & Webb, T. R. Br J Pharmacol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35802072
Performance of an electronic health record-based predictive model to identify patients with atrial fibrillation across countries. Mokgokong, R., Schnabel, R., Witt, H., Miller, R. & Lee, T. C. PLoS One 17, e0269867 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35802569
Informed Consent before coronary angiography and percutaneous coronary intervention from the patient's perspective: A picture is worth a thousand words. Brand, A., Crayen, C., Hamann, A., Martineck, S., Gao, L., Brand, H., Squier, S. M., Stangl, K., Kendel, F. & Stangl, V. Int J Cardiol Heart Vasc 41, 101076 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35800041
Multi-center study of inter-rater reproducibility, image quality, and diagnostic accuracy of CZT versus conventional SPECT myocardial perfusion imaging. Mansour, N., Nekolla, S. G., Reyes, E., Angelidis, G., Georgoulias, P., Anagnostopoulos, C., Bravo, P., Bruno, I., Flotats, A., Fuentes-Ocampo, F., Sciagra, R., Keng, F., Kessler, L., Papathanasiou, M., Soman, P. & Rischpler, C. J Nucl Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35799039
Serial Changes in Coronary Plaque Formation Using CT Angiography in Patients Undergoing PCSK9-Inhibitor Therapy With 1-year Follow-up. Baumann, S., Kettel, L., Stach, K., Ozdemir, G. H., Renker, M., Tesche, C., Becher, T., Hetjens, S., Schoepf, U. J., Akin, I., Borggrefe, M., Kramer, B. K., Schoenberg, S. O., Janssen, S., Overhoff, D. & Lossnitzer, D. J Thorac Imaging 37, 285-291 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35797638
Transcatheter edge-to-edge mitral valve repair in mitral regurgitation: current status and future prospects. Stolz, L., Braun, D., Higuchi, S., Orban, M., Doldi, P. M., Stocker, T. J., Weckbach, L. T., Wild, M. G., Hagl, C., Massberg, S., Nabauer, M., Hausleiter, J. & Orban, M. Expert Rev Med Devices, 1-10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35791872
Guideline-directed medical therapy in patients undergoing transcatheter edge-to-edge repair for secondary mitral regurgitation. Higuchi, S., Orban, M., Adamo, M., Giannini, C., Melica, B., Karam, N., Praz, F., Kalbacher, D., Koell, B., Stolz, L., Braun, D., Nabauer, M., Wild, M., Doldi, P., Neuss, M., Butter, C., Kassar, M., Ruf, T., Petrescu, A., Ludwig, S. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35791663
Assessment and Mitigation of Bleeding Risk in Atrial Fibrillation and Venous Thromboembolism: Executive Summary of a European and Asia-Pacific Expert Consensus Paper. Gorog, D. A., Gue, Y. X., Chao, T. F., Fauchier, L., Ferreiro, J. L., Huber, K., Konstantinidis, S. V., Lane, D. A., Marin, F., Oldgren, J., Potpara, T., Roldan, V., Rubboli, A., Sibbing, D., Tse, H. F., Vilahur, G. & Lip, G. Y. H. Thromb Haemost (2022). https://www.ncbi.nlm.nih.gov/pubmed/35793691
Elevated blood pressure in pregnant women with gestational diabetes according to the WHO criteria: importance of overweight. Birukov, A., Glintborg, D., Schulze, M. B., Jensen, T. K., Kuxhaus, O., Andersen, L. B., Kraker, K., Polemiti, E., Jensen, B. L., Jorgensen, J. S., Dechend, R. & Andersen, M. S. J Hypertens 40, 1614-1623 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35792096
Common electrocardiogram measures are not associated with telomere length. von Falkenhausen, A. S., Freudling, R., Waldenberger, M., Gieger, C., Peters, A., Muller-Nurasyid, M., Kaab, S. & Sinner, M. F. Aging (Albany NY) 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35787517
Blood circulating miR-28-5p and let-7d-5p associate with premature ageing in Down syndrome. Morsiani, C., Bacalini, M. G., Collura, S., Moreno-Villanueva, M., Breusing, N., Burkle, A., Grune, T., Franceschi, C., De Eguileor, M. & Capri, M. Mech Ageing Dev 206, 111691 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35780970
High-Mobility Group Box Protein 1 Is an Independent Prognostic Marker for All-Cause Mortality in Patients With Dilated Cardiomyopathy. Kummel, A., Gross, S., Feldtmann, R., Chamling, B., Strohbach, A., Lehnert, K., Bahls, M., Loerzer, L., Moormann, K., Witte, J., Riad, A., Dorr, M., Fielitz, J. & Felix, S. B. Am J Cardiol 178, 119-123 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35787339
The need for a subsequent transvenous system in patients implanted with subcutaneous implantable cardioverter-defibrillator. Gasperetti, A., Schiavone, M., Vogler, J., Laredo, M., Fastenrath, F., Palmisano, P., Ziacchi, M., Angeletti, A., Mitacchione, G., Kaiser, L., Compagnucci, P., Breitenstein, A., Arosio, R., Vitali, F., De Bonis, S., Picarelli, F., Casella, M., Santini, L., Pignalberi, C., Lavalle, C. et al. Heart Rhythm 19, 1958-1964 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35781042
Surgical treatment of isolated tricuspid valve endocarditis: Midterm data. Dzilic, E., Nobauer, C., Burri, M., Voss, S., Krane, M., Lange, R. & Vitanova, K. J Card Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35790024
WARS1 and SARS1: Two tRNA synthetases implicated in autosomal recessive microcephaly. Bogershausen, N., Krawczyk, H. E., Jamra, R. A., Lin, S. J., Yigit, G., Huning, I., Polo, A. M., Vona, B., Huang, K., Schmidt, J., Altmuller, J., Luppe, J., Platzer, K., Dorgeloh, B. B., Busche, A., Biskup, S., Mendes, M. I., Smith, D. E. C., Salomons, G. S., Zibat, A. et al. Hum Mutat (2022). https://www.ncbi.nlm.nih.gov/pubmed/35790048
Ticagrelor or prasugrel in patients with acute coronary syndrome with off-hour versus on-hour presentation: a subgroup analysis of the ISAR-REACT 5 trial. Behnes, M., Lahu, S., Ndrepepa, G., Menichelli, M., Mayer, K., Wohrle, J., Bernlochner, I., Gewalt, S., Witzenbichler, B., Hochholzer, W., Sibbing, D., Cassese, S., Angiolillo, D. J., Hemetsberger, R., Valina, C., Muller, A., Kufner, S., Hamm, C. W., Xhepa, E., Hapfelmeier, A. et al. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35789430
Minimally Clinically Important Difference in Health Status Scores in Patients With HFrEF vs HFpEF. Butler, J., Shahzeb Khan, M., Lindenfeld, J., Abraham, W. T., Savarese, G., Salsali, A., Zeller, C., Peil, B., Filippatos, G., Ponikowski, P. & Anker, S. D. JACC Heart Fail 10, 651-661 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35780032
Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial. Barco, S., Voci, D., Held, U., Sebastian, T., Bingisser, R., Colucci, G., Duerschmied, D., Frenk, A., Gerber, B., Gotschi, A., Konstantinides, S. V., Mach, F., Robert-Ebadi, H., Rosemann, T., Simon, N. R., Spechbach, H., Spirk, D., Stortecky, S., Vaisnora, L., Righini, M. et al. Lancet Haematol 9, e585-e593 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35779558
Assessment of the association of exposure to polycyclic aromatic hydrocarbons, oxidative stress, and inflammation: A cross-sectional study in Augsburg, Germany. Wu, X., Cao, X., Lintelmann, J., Peters, A., Koenig, W., Zimmermann, R., Schneider, A., Wolf, K. & group, K. O.-S. Int J Hyg Environ Health 244, 113993 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35777219
ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver. Schmid, C. D., Olsavszky, V., Reinhart, M., Weyer, V., Trogisch, F. A., Sticht, C., Winkler, M., Kurschner, S. W., Hoffmann, J., Ola, R., Staniczek, T., Heineke, J., Straub, B. K., Mittler, J., Schledzewski, K., Ten Dijke, P., Richter, K., Dooley, S., Geraud, C., Goerdt, S. et al. Hepatology(2022). https://www.ncbi.nlm.nih.gov/pubmed/35776660
Cardio-respiratory motion-corrected 3D cardiac water-fat MRI using model-based image reconstruction. Mayer, J., Blaszczyk, E., Cipriani, A., Ferrazzi, G., Schulz-Menger, J., Schaeffter, T. & Kolbitsch, C. Magn Reson Med 88, 1561-1574 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35775790
Exercise Testing in HFpEF: an Appraisal Through Diagnosis, Pathophysiology and Therapy A Clinical Consensus Statement of the Heart Failure Association (HFA) and European Association of Preventive Cardiology (EAPC) of the European Society of Cardiology (ESC). Marco Guazzi, M., Wilhelm, M., Halle, M., Van Craenenbroeck, E., Kemps, H., de Boer, R. A., Coats, A. J., Lund, L., Mancini, D., Borlaug, B., Filippatos, G. & Pieske, B. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35775383
The baroreceptor reflex brought to life outside the classroom - an e-learning based asynchronous laboratory class using a non-supervised modified Active Standing Test. Heinrich, T., Sehner, S., Wageringel, I., Ehmke, H. & Schwoerer, A. P. BMC Med Educ 22, 515 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35778720
The association of smoking and smoking cessation with prevalent and incident symptoms of depression, anxiety, and sleep disturbance in the general population. Hahad, O., Beutel, M., Gilan, D. A., Michal, M., Schulz, A., Pfeiffer, N., Konig, J., Lackner, K., Wild, P., Daiber, A. & Munzel, T. J Affect Disord313, 100-109 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35777492
Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy - A clinical consensus statement of the Heart Failure Association and European Association of Preventive Cardiology of the European Society of Cardiology. Guazzi, M., Wilhelm, M., Halle, M., Van Craenenbroeck, E., Kemps, H., de Boer, R. A., Coats, A. J. S., Lund, L., Mancini, D., Borlaug, B., Filippatos, G. & Pieske, B. Eur J Heart Fail 24, 1327-1345 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35775383
Identification of risk factors for delirium, cognitive decline, and dementia after cardiac surgery (FINDERI-find delirium risk factors): a study protocol of a prospective observational study. Sadlonova, M., Vogelgsang, J., Lange, C., Gunther, I., Wiesent, A., Eberhard, C., Ehrentraut, J., Kirsch, M., Hansen, N., Esselmann, H., Timaus, C., Asendorf, T., Breitling, B., Chebbok, M., Heinemann, S., Celano, C., Kutschka, I., Wiltfang, J., Baraki, H. & von Arnim, C. A. F. BMC Cardiovasc Disord 22, 299 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35773648
Fibrotic plaques in heart transplanted patients and their association with insulin resistance syndrome and Lp(a). Orban, M., Kuehl, A., Dischl, D., Muller, C., Ulrich, S., Petzold, T., Rizas, K. D., Orban, M., Braun, D., Hausleiter, J., Hagl, C., Mehilli, J. & Massberg, S. Int J Cardiol 363, 218-224 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35772579
Soil and water pollution and human health: what should cardiologists worry about? Munzel, T., Hahad, O., Daiber, A. & Landrigan, P. J. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35772469
Genetics and Epigenetics in Personalized Nutrition: Evidence, Expectations, and Experiences. Holzapfel, C., Waldenberger, M., Lorkowski, S., Daniel, H. & Working Group "Personalized Nutrition" of the German Nutrition, S. Mol Nutr Food Res 66, e2200077 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35770348
August
Paper of the Month
AAV-Mediated Somatic Gene Editing for Cardiac and Skeletal Muscle in a Large Animal Model. Ziegler, T., Bozoglu, T. & Kupatt, C. Methods Mol Biol 2573, 63-74 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36040587
Enhancing Cardiomyocyte Transcription Using In Vivo CRISPR/Cas9 Systems. Schoger, E. & Zelarayan, L. C. Methods Mol Biol 2573, 53-61 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36040586
Cardiac Gene Delivery in Large Animal Models: Selective Retrograde Venous Injection. Schlegel, P. & Raake, P. W. J. Methods Mol Biol 2573, 171-177 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36040594
Concomitant cardiovascular malformations in isolated bicuspid aortic valve disease: a retrospective cross-sectional study and meta-analysis. Szocs, K., Toprak, B., Schon, G., Rybczynski, M., Brinken, T., Mahlmann, A., Girdauskas, E., Blankenberg, S. & von Kodolitsch, Y. Cardiovasc Diagn Ther 12, 400-414 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36033227
Rationale and design of the AXIOMATIC-SSP phase II trial: Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events for Secondary Stroke Prevention. Sharma, M., Molina, C. A., Toyoda, K., Bereczki, D., Kasner, S. E., Lutsep, H. L., Tsivgoulis, G., Ntaios, G., Czlonkowska, A., Shuaib, A., Amarenco, P., Endres, M., Diener, H. C., Gailani, D., Kahl, A., Donovan, M., Perera, V., Li, D. & Hankey, G. J. J Stroke Cerebrovasc Dis 31, 106742 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36037679
Rationale and design of the prevention of paclitaxel-related neurological side effects with lithium trial - Protocol of a multicenter, randomized, double-blind, placebo- controlled proof-of-concept phase-2 clinical trial. Huehnchen, P., Bangemann, N., Lischewski, S., Marschenz, S., Paul, F., Schmitz-Hubsch, T., Blohmer, J. U., Eberhardt, C., Rauch, G., Floel, A., Adam, S., Schwenkenbecher, P., Meinhold-Heerlein, I., Hoffmann, O., Ziemssen, T., Endres, M. & Boehmerle, W. Front Med (Lausanne) 9, 967964 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36035422
Neutrophils incite and macrophages avert electrical storm after myocardial infarction. Grune, J.,Lewis, A. J. M., Yamazoe, M., Hulsmans, M., Rohde, D., Xiao, L., Zhang, S., Ott, C., Calcagno, D. M., Zhou, Y., Timm, K., Shanmuganathan, M., Pulous, F. E., Schloss, M. J., Foy, B. H., Capen, D., Vinegoni, C., Wojtkiewicz, G. R., Iwamoto, Y., Grune, T. et al. Nat Cardiovasc Res 1, 649-664 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36034743
Characteristics and Prognostic Relevance of Ventricular Arrhythmia in Patients with Myocarditis. Kahle, A. K., Gude, R., Schwarzl, J. M., Munkler, P., Akbulak, R. O., Jahnke, C., Bohnen, S., Wurger, T., Schwarzl, M., Willems, S., Radunski, U. K. & Meyer, C. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36005407
The pleiotropic benefits of statins include the ability to reduce CD47 and amplify the effect of pro-efferocytic therapies in atherosclerosis. Jarr, K. U., Ye, J., Kojima, Y., Ye, Z., Gao, H., Schmid, S., Luo, L., Baylis, R. A., Lotfi, M., Lopez, N., Eberhard, A. V., Smith, B. R., Weissman, I. L., Maegdefessel, L. & Leeper, N. J. Nat Cardiovasc Res 1, 253-262 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35990913
Longer leukocyte telomere length is associated with myeloid inflammation and increased mortality after transcatheter aortic valve replacement. Hoffmann, J., Tabata, N., Mas-Peiro, S., Spyridopoulos, I., Sinning, J. M., Berkowitsch, A., Martin-Ruiz, C., Al-Kassou, B., Herrmann, E., Dimmeler, S., Zeiher, A. M. & Vasa-Nicotera, M. Eur Heart J Open 2, oeac045 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35983406
Mechanical thrombectomy in ischemic stroke after cardiovascular procedures: a propensity-matched cohort analysis. Bay, B., Gloyer, N. O., Remmel, M., Schell, M., Zelenak, K., Seiffert, M., Brunner, F. J., Clemmensen, P., Reichenspurner, H., Blankenberg, S., Thomalla, G., Fiehler, J., Conradi, L., Waldeyer, C. & Flottmann, F. J Neurointerv Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35985838
Step-by-step diagnosis and management of the nocebo/drucebo effect in statin-associated muscle symptoms patients: a position paper from the International Lipid Expert Panel (ILEP). Penson, P. E., Bruckert, E., Marais, D., Reiner, Z., Pirro, M., Sahebkar, A., Bajraktari, G., Mirrakhimov, E., Rizzo, M., Mikhailidis, D. P., Sachinidis, A., Gaita, D., Latkovskis, G., Mazidi, M., Toth, P. P., Pella, D., Alnouri, F., Postadzhiyan, A., Yeh, H. I., Mancini, G. B. J. et al. J Cachexia Sarcopenia Muscle 13, 1596-1622 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35969116
Left ventricle- and skeletal muscle-derived fibroblasts exhibit a differential inflammatory and metabolic responsiveness to interleukin-6. Matz, I., Pappritz, K., Springer, J. & Van Linthout, S. Front Immunol 13, 947267 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35967380
A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells. Zhong, R., Schimanski, T., Zhang, F., Lan, H., Hohn, A., Xu, Q., Huang, M., Liao, Z., Qiao, L., Yang, Z., Li, Y., Zhao, Z., Li, X., Rose, L., Albers, S., Maywald, L., Muller, J., Dinkel, H., Saguner, A., Janssen, J. W. G. et al. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35955449
High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome-A Subanalysis of the Randomised-Controlled ACOORH Trial. Kempf, K., Rohling, M., Banzer, W., Braumann, K. M., Halle, M., Schaller, N., McCarthy, D., Predel, H. G., Schenkenberger, I., Tan, S., Toplak, H., Martin, S., Berg, A. & On Behalf Of The Acoorh Study, G. Nutrients14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35956337
Cardiovascular risk factors, exercise capacity and health literacy in patients with chronic ischaemic heart disease and type 2 diabetes mellitus in Germany: Baseline characteristics of the Lifestyle Intervention in Chronic Ischaemic Heart Disease and Type 2 Diabetes study. Dinges, S. M., Krotz, J., Gass, F., Treitschke, J., Fegers-Wustrow, I., Geisberger, M., Esefeld, K., von Korn, P., Duvinage, A., Edelmann, F., Wolfram, O., Brandts, J., Winzer, E. B., Wolfarth, B., Freigang, F., Neubauer, S., Nebling, T., Hackenberg, B., Amelung, V., Mueller, S. et al. Diab Vasc Dis Res 19, 14791641221113781 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35953083
Valve embolization during transcatheter aortic valve implantation: Incidence, risk factors and follow-up by computed tomography. Frumkin, D., Pietron, M., Kind, A., Brand, A., Knebel, F., Laule, M., Leistner, D. M., Landmesser, U., Krackhardt, F., Sherif, M., Sundermann, S. H., Grubitzsch, H., Lembcke, A., Niehues, S. M., Stangl, K. & Dreger, H. Front Cardiovasc Med 9, 928740 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35935663
Full-Length Spatial Transcriptomics Reveals the Unexplored Isoform Diversity of the Myocardium Post-MI. Boileau, E., Li, X., Naarmann-de Vries, I. S., Becker, C., Casper, R., Altmuller, J., Leuschner, F. & Dieterich, C. Front Genet 13, 912572 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35937994
Platelets in Myocardial Ischemia/Reperfusion Injury. Schanze, N., Hamad, M. A., Nuhrenberg, T. G., Bode, C. & Duerschmied, D. Hamostaseologie (2022). https://www.ncbi.nlm.nih.gov/pubmed/35913081
Editorial: Impact of the gut microbiota on cardiovascular medicine. Haghikia, A., van Mens, T. E., Pontarollo, G. & Reinhardt, C. Front Med (Lausanne) 9, 939890 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35911413
Different Impacts on the Heart After COVID-19 Infection and Vaccination: Insights From Cardiovascular Magnetic Resonance. Groschel, J., Bhoyroo, Y., Blaszczyk, E., Trauzeddel, R. F., Viezzer, D., Saad, H., Fenski, M. & Schulz-Menger, J. Front Cardiovasc Med 9, 916922 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35911510
Congestion in heart failure: a circulating biomarker-based perspective. A review from the Biomarkers Working Group of the Heart Failure Association, European Society of Cardiology. Nunez, J., de la Espriella, R., Rossignol, P., Voors, A. A., Mullens, W., Metra, M., Chioncel, O., Januzzi, J. L., Mueller, C., Richards, A. M., de Boer, R. A., Thum, T., Arfsten, H., Gonzalez, A., Abdelhamid, M., Adamopoulos, S., Anker, S. D., Gal, T. B., Biegus, J., Cohen-Solal, A. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36039656
A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming. Lyra-Leite, D. M., Gutierrez-Gutierrez, O., Wang, M., Zhou, Y., Cyganek, L. & Burridge, P. W. STAR Protoc 3, 101560 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36035804
Putting the puzzle together: SGLT2 inhibitors from prevention to treatment of heart failure. Harrington, J., Anker, S. & Butler, J. Eur Heart J 43, 4433-4435 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36036745
Attaining sinus rhythm mediates improved outcome with early rhythm control therapy of atrial fibrillation: the EAST - AFNET 4 trial. Eckardt, L., Sehner, S., Suling, A., Borof, K., Breithardt, G., Crijns, H., Goette, A., Wegscheider, K., Zapf, A., Camm, A. J., Metzner, A. & Kirchhof, P. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36036648
Sodium-glucose cotransporter 2 inhibitor treatment lowers serum uric acid in patients with heart failure with reduced ejection fraction - lessons from clinical trials. Letter regarding the article 'Dapagliflozin reduces uric acid concentration, an independent predictor of adverse outcomes in DAPA-HF'. Doehner, W. & Packer, M. Eur J Heart Fail (2022).
[Hypertrophic cardiomyopathies and ATTR amyloidosis - a current review for clinical practice]. Tschope, C., Elsanhoury, A., Diekmann, S. & Kuhl, U. Dtsch Med Wochenschr 147, 1127-1134 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36030786
Smartphone-based screening for atrial fibrillation: a pragmatic randomized clinical trial. Rizas, K. D., Freyer, L., Sappler, N., von Stülpnagel, L., Spielbichler, P., Krasniqi, A., Schreinlechner, M., Wenner, F. N., Theurl, F., Behroz, A., Eiffener, E., Klemm, M. P., Schneidewind, A., Zens, M., Dolejsi, T., Mansmann, U., Massberg, S. & Bauer, A. Nature Medicine (2022).
Coronary artery disease and revascularization associated with immune checkpoint blocker myocarditis: Report from an international registry. Nowatzke, J., Guedeney, P., Palaskas, N., Lehmann, L., Ederhy, S., Zhu, H., Cautela, J., Francis, S., Courand, P. Y., Deswal, A., Ewer, S. M., Aras, M., Arangalage, D., Ghafourian, K., Fenioux, C., Finke, D., Peretto, G., Zaha, V., Itzhaki Ben Zadok, O., Tajiri, K. et al. Eur J Cancer177, 197-205 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36030143
'Normal Weight' Is Really Not Normal in Chronic Disease. Anker, S. D., Usman, M. S. & Butler, J. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36029317
Effect of Empagliflozin on Circulating Proteomics in Heart Failure: Mechanistic Insights from the EMPEROR Program. Zannad, F., Ferreira, J. P., Butler, J., Filippatos, G., Januzzi, J. L., Sumin, M., Zwick, M., Saadati, M., Pocock, S. J., Sattar, N., Anker, S. D. & Packer, M. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36017745
Retinol and Retinol Binding Protein 4 Levels and Cardiometabolic Disease Risk. Schiborn, C., Weber, D., Grune, T., Biemann, R., Jager, S., Neu, N., Muller von Blumencron, M., Fritsche, A., Weikert, C., Schulze, M. B. & Wittenbecher, C. Circ Res, 101161CIRCRESAHA122321295 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36017698
High-sensitivity troponin I with or without ultra-sensitive copeptin for the instant rule-out of acute myocardial infarction. Ricci, F., Neumann, J. T., Rubsamen, N., Sorensen, N. A., Ojeda, F., Cataldo, I., Zeller, T., Schafer, S., Hartikainen, T. S., Golato, M., Palermi, S., Zimarino, M., Blankenberg, S., Westermann, D. & De Caterina, R. Front Cardiovasc Med 9, 895421 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36017085
A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation. Reininghaus, N., Paisdzior, S., Hopfner, F., Jyrch, S., Cetindag, C., Scheerer, P., Kuhnen, P. & Biebermann, H. Biomolecules 12(2022). https://www.ncbi.nlm.nih.gov/pubmed/36009013
AVNeo Improves Early Hemodynamics In Regurgitant Bicuspid Aortic Valves Compared To Aortic Valve Repair. Prinzing, A., Bohm, J., Sideris, K., Vitanova, K., Lange, R. & Krane, M. Interact Cardiovasc Thorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/36018270
Harmful Impact of Tobacco Smoking and Alcohol Consumption on the Atrial Myocardium. Ohlrogge, A. H., Frost, L. & Schnabel, R. B. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36010652
Mobile Access to Medical Records in Heart Transplantation Aftercare: Mixed-Methods Study Assessing Usability, Feasibility and Effects of a Mobile Application. Muller, J., Weinert, L., Svensson, L., Rivinius, R., Kreusser, M. M. & Heinze, O. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36013383
Novel cryoballoon ablation system for pulmonary vein isolation: multicenter assessment of efficacy and safety-ANTARCTICA study. Heeger, C. H., Pott, A., Sohns, C., Riesinger, L., Sommer, P., Gasperetti, A., Tondo, C., Fassini, G., Moser, F., Lucas, P., Weinmann, K., Bohnen, J. E., Dahme, T., Rillig, A., Kuck, K. H., Wakili, R., Metzner, A. & Tilz, R. R. Europace 24, 1917-1925 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36026521
Periostin Augments Vascular Smooth Muscle Cell Calcification via beta-Catenin Signaling. Alesutan, I., Henze, L. A., Boehme, B., Luong, T. T. D., Zickler, D., Pieske, B., Eckardt, K. U., Pasch, A. & Voelkl, J. Biomolecules 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36009051
Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly. Tas, K., Volta, B. D., Lindner, C., El Bounkari, O., Hille, K., Tian, Y., Puig-Bosch, X., Ballmann, M., Hornung, S., Ortner, M., Prem, S., Meier, L., Rammes, G., Haslbeck, M., Weber, C., Megens, R. T. A., Bernhagen, J. & Kapurniotu, A. Nat Commun 13, 5004 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36008417
Neointimal hyperplasia in systemic-to-pulmonary shunts of children with complex cyanotic congenital heart disease. Kottmann, P., Cleuziou, J., Lemmer, J., Eildermann, K., Vitanova, K., von-Stumm, M., Lehmann, L., Horer, J., Ewert, P., Sigler, M. & Wolf, C. M. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/36005853
Inverse relationship between IL-6 and sodium levels in patients with COVID-19 and other respiratory tract infections: data from the COVIVA study. Atila, C., Monnerat, S., Bingisser, R., Siegemund, M., Lampart, M., Rueegg, M., Zellweger, N., Osswald, S., Rentsch, K., Christ-Crain, M. & Twerenbold, R. Endocr Connect 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36006851
Intravascular molecular imaging: translating pathophysiology of atherosclerosis into human disease conditions. Seguchi, M., Aytekin, A., Lenz, T., Nicol, P., Klosterman, G. R., Beele, A., Sabic, E., Utsch, L., Alyaqoob, A., Gorpas, D., Ntziachristos, V., Jaffer, F. A., Rauschendorfer, P. & Joner, M. Eur Heart J Cardiovasc Imaging 24, e1-e16 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36002376
NGS-driven molecular diagnosis of heterogeneous hereditary neurological disorders reveals novel and known variants in disease-causing genes. Khan, A., Tian, S., Tariq, M., Khan, S., Safeer, M., Ullah, N., Akbar, N., Javed, I., Asif, M., Ahmad, I., Ullah, S., Satti, H. S., Khan, R., Naeem, M., Ali, M., Rendu, J., Faure, J., Dieterich, K., Latypova, X., Baig, S. M. et al. Mol Genet Genomics (2022). https://www.ncbi.nlm.nih.gov/pubmed/36002593
ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7. Garcia-Gonzalez, C., Dieterich, C., Maroli, G., Wiesnet, M., Wietelmann, A., Li, X., Yuan, X., Graumann, J., Stellos, K., Kubin, T., Schneider, A. & Braun, T. Circ Res, 101161CIRCRESAHA122320839 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36000401
Association of In-Hospital Hemoglobin Drop With Decreased Myocardial Salvage and Increased Long-Term Mortality in Patients With Acute ST-Segment-Elevation Myocardial Infarction. Dutsch, A., Graesser, C., Voll, F., Novacek, S., Eggerstedt, R., Armbruster, N. L., Laugwitz, K. L., Cassese, S., Schunkert, H., Ndrepepa, G., Kastrati, A., Kessler, T. & Sager, H. B. J Am Heart Assoc, e024857 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36000430
Left ventricular assist device related infections and the risk of cerebrovascular accidents: a EUROMACS study. Zijderhand, C. F., Antonides, C. F. J., Veen, K. M., Verkaik, N. J., Schoenrath, F., Gummert, J., Nemec, P., Merkely, B., Musumeci, F., Meyns, B., de By, T., Bogers, A. & Caliskan, K. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35997578
ARDS in the Time of Corona: Context and Perspective. Voelkel, N. F., Bogaard, H. J. & Kuebler, W. M. Am J Physiol Lung Cell Mol Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35997290
Boosters for adeno-associated virus vector (AAV) (r)evolution. Szumska, J. & Grimm, D. Cytotherapy(2022). https://www.ncbi.nlm.nih.gov/pubmed/35999132
The sound of drug delivery: optoacoustic imaging in pharmacology. Liu, N., Mishra, K., Stiel, A. C., Gujrati, V. & Ntziachristos, V. Adv Drug Deliv Rev, 114506 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35998826
Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols. Schildknecht, S., von Kriegsheim, A., Vujacic-Mirski, K., Di Lisa, F., Ullrich, V. & Daiber, A. Redox Biol 56, 102439 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35995009
Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle. Munkler, P., Klatt, N., Scherschel, K., Kuklik, P., Jungen, C., Cavus, E., Eickholt, C., Christoph, J., Lemoine, M. D., Christ, T., Willems, S., Riedel, R., Kirchhof, P. & Meyer, C. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/35989424
Two-Faced Janus: CCR2-Expressing Macrophages and Their Dual Role in Allograft Rejection of the Transplanted Heart. Farina, F. M., Santovito, D. & Weber, C. Circulation 146, 639-642 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35994560
Use of intravascular ultrasound for optimal vessel sizing in chronic total occlusion percutaneous coronary intervention. Blessing, R., Buono, A., Ahoopai, M., Geyer, M., Knorr, M., Brandt, M., Steven, S., Drosos, I., Muenzel, T., Wenzel, P., Gori, T. & Dimitriadis, Z. Front Cardiovasc Med 9, 922366 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35990972
Effective high-density lipoprotein cholesterol is associated with carotid intima-media thickness and vascular events after acute ischemic stroke. Schwedhelm, E., Tiedt, S., Lezius, S., Wolfer, T. A., Jensen, M., Schulz, R., Boger, R., Gerloff, C., Thomalla, G. & Choe, C. U. Atherosclerosis 357, 9-13 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35988315
Genetic and modifiable risk factors combine multiplicatively in common disease. Pang, S., Yengo, L., Nelson, C. P., Bourier, F., Zeng, L., Li, L., Kessler, T., Erdmann, J., Magi, R., Lall, K., Metspalu, A., Mueller-Myhsok, B., Samani, N. J., Visscher, P. M. & Schunkert, H. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35987817
Quality of life of patients with coronary heart disease treated with the bioresorbable vascular scaffold (ABSORB): 2-year results from the GABI-R-registry. Pahmeier, K., Neusser, S., Hamm, C., Kastner, J., Wohrle, J., Zahn, R., Achenbach, S., Mehilli, J., Gori, T., Naber, C., Nef, H., Neumann, T., Richardt, G., Schmermund, A., Claas, C., Riemer, T., Biermann-Stallwitz, J. & Group, G.-R. S. BMC Cardiovasc Disord 22, 379 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35987601
Venting during venoarterial extracorporeal membrane oxygenation. Lusebrink, E., Binzenhofer, L., Kellnar, A., Muller, C., Scherer, C., Schrage, B., Joskowiak, D., Petzold, T., Braun, D., Brunner, S., Peterss, S., Hausleiter, J., Zimmer, S., Born, F., Westermann, D., Thiele, H., Schafer, A., Hagl, C., Massberg, S. & Orban, M. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35986750
Blinded sample size recalculation in adaptive enrichment designs. Placzek, M. & Friede, T. Biom J(2022). https://www.ncbi.nlm.nih.gov/pubmed/35983952
Prognostic value of De Ritis ratio in patients with acute myocardial infarction. Ndrepepa, G., Holdenrieder, S. & Kastrati, A. Clin Chim Acta 535, 75-81 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35985502
Inflammation in Children with CKD Linked to Gut Dysbiosis and Metabolite Imbalance. Holle, J., Bartolomaeus, H., Lober, U., Behrens, F., Bartolomaeus, T. U. P., Anandakumar, H., Wimmer, M. I., Vu, D. L., Kuhring, M., Bruning, U., Maifeld, A., Geisberger, S., Kempa, S., Schumacher, F., Kleuser, B., Bufler, P., Querfeld, U., Kitschke, S., Engler, D., Kuhrt, L. D. et al. J Am Soc Nephrol 33, 2259-2275 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35985814
Biventricular strain assessment indicates progressive impairment of myocardial contractility in phenotypically negative patients with Fabry's disease. Halfmann, M. C., Benz, S., Schoepf, U. J., Hennermann, J. B., Kreitner, K. F., Lollert, A., Dueber, C., Altmann, S., Varga-Szemes, A., Kampmann, C. & Emrich, T. Eur J Radiol 155, 110471 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35985091
Concomitant mitral regurgitation in patients with low-gradient aortic stenosis: an analysis from the German Aortic Valve Registry. Alushi, B., Ensminger, S., Herrmann, E., Balaban, U., Bauer, T., Beckmann, A., Bleiziffer, S., Mollmann, H., Walther, T., Bekeredjian, R., Hamm, C., Beyersdorf, F., Baldus, S., Boening, A., Falk, V., Thiele, H., Frerker, C. & Lauten, A. Clin Res Cardiol 111, 1377-1386 (2022). www.ncbi.nlm.nih.gov/pubmed/35984497
Thromboinflammation in cardiovascular disease: lessons learned for the management of hypertension, heart failure, and aortic valve stenosis. Wenzel, P. Eur Heart J 43, 4611-4613 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35979817
Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization. Tappu, R., Haas, J., Lehmann, D. H., Sedaghat-Hamedani, F., Kayvanpour, E., Keller, A., Katus, H. A., Frey, N. & Meder, B. PLoS One 17, e0272093 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35980883
Ticagrelor with and without aspirin in patients with a prior coronary artery bypass graft undergoing percutaneous coronary intervention: the TWILIGHT-CABG study. Sardella, G., Beerkens, F. J., Dangas, G., Cao, D., Baber, U., Sartori, S., Cohen, D. J., Briguori, C., Gil, R., Nicolas, J., Zhang, Z., Dudek, D., Kunadian, V., Kornowski, R., Weisz, G., Claessen, B., Marx, S. O., Escaned, J., Huber, K., Collier, T. et al.EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/35979636
Nitric oxide metabolites: associations with cardiovascular biomarkers and clinical parameters in patients with HFpEF. Piatek, K., Feuerstein, A., Zach, V., Rozados da Conceicao, C., Beblo, A., Belyavskiy, E., Pieske-Kraigher, E., Krannich, A., Schwedhelm, E., Hinz, S., Pieske, B. & Edelmann, F. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/35979962
COVID-19 infection and its impact on case-fatality in patients with pulmonary embolism. Hobohm, L., Sagoschen, I., Barco, S., Farmakis, I. T., Fedeli, U., Koelmel, S., Gori, T., Espinola-Klein, C., Munzel, T., Konstantinides, S. & Keller, K. Eur Respir J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35981745
Why do we climb mountains? An exploration of features of behavioural addiction in mountaineering and the association with stress-related psychiatric disorders. Habelt, L., Kemmler, G., Defrancesco, M., Spanier, B., Henningsen, P., Halle, M., Sperner-Unterweger, B. & Hufner, K. Eur Arch Psychiatry Clin Neurosci (2022). https://www.ncbi.nlm.nih.gov/pubmed/35980451
Impact of genetic deletion of MrgD or Mas receptors in depressive-like behavior in mice. Becari, L., Fonseca, M. L. A., Goncalves, S. C. A., Bader, M., Santos, R. A. S., Campagnole-Santos, M. J. & Kangussu, L. M. Acta Neuropsychiatr, 1-24 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35979816
PrEdictive value of coMbined pre-test proBability and blOod gas anaLysis In pulmonary emboliSM-the EMBOLISM study. Meusel, M., Patz, T., Gruber, K., Kupp, S., Jensch, P. J., Saraei, R., Furschke, A., Sayk, F., Eitel, I. & Wolfrum, S. Intern Emerg Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/35976533
Inhibitory Effect of Epigallocatechin Gallate-Silver Nanoparticles and Their Lysozyme Bioconjugates on Biofilm Formation and Cytotoxicity. Meesaragandla, B., Hayet, S., Fine, T., Janke, U., Chai, L. & Delcea, M. ACS Appl Bio Mater (2022). https://www.ncbi.nlm.nih.gov/pubmed/35977081
Clinical characteristics, causes and predictors of outcomes in patients with in-hospital cardiac arrest: results from the SURVIVE-ARREST study. Hannen, L. E. M., Toprak, B., Weimann, J., Mahmoodi, B., Fluschnik, N., Schrage, B., Roedl, K., Soffker, G., Kluge, S., Issleib, M., Blankenberg, S., Kirchhof, P., Clemmensen, P., Sinning, C., Zengin-Sahm, E. & Becher, P. M. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/35978110
Clonal hematopoiesis confers an increased mortality risk in orthotopic heart transplant recipients. Scolari, F. L., Brahmbhatt, D. H., Abelson, S., Medeiros, J. J. F., Anker, M. S., Fung, N. L., Otsuki, M., Calvillo-Arguelles, O., Lawler, P. R., Ross, H. J., Luk, A. C., Anker, S., Dick, J. E. & Billia, F. Am J Transplant 22, 3078-3086 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35971851
Imaging of heart disease in women: review and case presentation. Mikail, N., Rossi, A., Bengs, S., Haider, A., Stahli, B. E., Portmann, A., Imperiale, A., Treyer, V., Meisel, A., Pazhenkottil, A. P., Messerli, M., Regitz-Zagrosek, V., Kaufmann, P. A., Buechel, R. R. & Gebhard, C. Eur J Nucl Med Mol Imaging 50, 130-159 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35974185
Dataset of ileum bacterial diversity in mice after heart failure due to pressure overload. Spehlmann, M. E., Dhotre, D. P., Schmiedel, N., Chavan, N., Bang, C. & Rangrez, A. Y. Data Brief 44, 108498 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35966944
Outcomes of aortic valve repair: early results from the German Aortic Valve Registry. Girdauskas, E., Petersen, J., Balaban, U., Herrmann, E., Bauer, T., Beckmann, A., Bekeredjian, R., Ensminger, S., Frerker, C., Mollmann, H., Walther, T. & Bleiziffer, S. Eur J Cardiothorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/35962722
Thyroid hormones as a disease modifier and therapeutic target in nonalcoholic steatohepatitis. Wirth, E. K., Puengel, T., Spranger, J. & Tacke, F. Expert Rev Endocrinol Metab 17, 425-434 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35957531
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes. Shi, J. Z., Zheng, X. M., Zhou, Y. F., Yun, L. Y., Luo, D. M., Hao, J. J., Liu, P. F., Zhang, W. K., Xu, J. K., Yan, Y., Xie, X. M., He, Y. Y. & Pang, X. B. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35956355
Regulation of APD and Force by the Na(+)/Ca(2+) Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue. Ismaili, D., Gurr, K., Horvath, A., Yuan, L., Lemoine, M. D., Schulz, C., Sani, J., Petersen, J., Reichenspurner, H., Kirchhof, P., Jespersen, T., Eschenhagen, T., Hansen, A., Koivumaki, J. T. & Christ, T. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35954268
Serum of Post-COVID-19 Syndrome Patients with or without ME/CFS Differentially Affects Endothelial Cell Function In Vitro. Flaskamp, L., Roubal, C., Uddin, S., Sotzny, F., Kedor, C., Bauer, S., Scheibenbogen, C. & Seifert, M. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35954219
Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells. Fan, X., Cyganek, L., Nitschke, K., Uhlig, S., Nuhn, P., Bieback, K., Duerschmied, D., El-Battrawy, I., Zhou, X. & Akin, I. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35955642
Time's up: mutation rate and lifespan. Cremer, A., Abplanalp, W. T. & Rieger, M. A. Signal Transduct Target Ther 7, 282 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35961971
The beneficial therapeutic effects of plant-derived natural products for the treatment of sarcopenia. Bagherniya, M., Mahdavi, A., Shokri-Mashhadi, N., Banach, M., Von Haehling, S., Johnston, T. P. & Sahebkar, A. J Cachexia Sarcopenia Muscle 13, 2772-2790 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35961944
Limited evidence for blood eQTLs in human sexual dimorphism. Porcu, E., Claringbould, A., Weihs, A., Lepik, K., Consortium, B., Richardson, T. G., Volker, U., Santoni, F. A., Teumer, A., Franke, L., Reymond, A. & Kutalik, Z. Genome Med 14, 89 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35953856
Identification of novel genes whose expression in adipose tissue affects body fat mass and distribution: an RNA-Seq and Mendelian Randomization study. Konigorski, S., Janke, J., Patone, G., Bergmann, M. M., Lippert, C., Hubner, N., Kaaks, R., Boeing, H. & Pischon, T. Eur J Hum Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/35953519
The multifaceted actions of the lncRNA H19 in cardiovascular biology and diseases. Busscher, D., Boon, R. A. & Juni, R. P. Clin Sci (Lond) 136, 1157-1178 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35946958
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI. Yang, Y., Knol, M. J., Wang, R., Mishra, A., Liu, D., Luciano, M., Teumer, A., Armstrong, N., Bis, J. C., Jhun, M. A., Li, S., Adams, H. H. H., Aziz, N. A., Bastin, M. E., Bourgey, M., Brody, J. A., Frenzel, S., Gottesman, R. F., Hosten, N., Hou, L. et al. Brain (2022). https://www.ncbi.nlm.nih.gov/pubmed/35943854
Safety and usefulness of left ventricular endomyocardial biopsy in new- onset acute heart failure requiring mechanical support by an Impella(R) device. Tschope, C., Nelki, V., Trippel, T. D., Klingel, K., Abawi, D. & Alogna, A. Int J Cardiol 368, 49-52 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35944774
Hypverventilation strain CMR imaging in patients with acute chest pain. Siry, D., Riffel, J. H., Salatzki, J., Andre, F., Ochs, M., Weberling, L. D., Giannitsis, E., Katus, H. A. & Friedrich, M. G. Sci Rep 12, 13584 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35945332
Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption. Mackert, O., Wirth, E. K., Sun, R., Winkler, J., Liu, A., Renko, K., Kunz, S., Spranger, J. & Brachs, S. Mol Metab64, 101563 (2022).
Impact of moderate or severe left ventricular outflow tract calcification on clinical outcomes of patients with severe aortic stenosis undergoing transcatheter aortic valve implantation with self- and balloon-expandable valves: a post hoc analysis from the SOLVE-TAVI trial. Farhan, S., Stachel, G., Desch, S., Kurz, T., Feistritzer, H. J., Hartung, P., Eitel, I., Nef, H., Doerr, O., Lauten, A., Landmesser, U., Sandri, M., Holzhey, D., Borger, M., Ince, H., Oner, A., Meyer-Saraei, R., Wienbergen, H., Fach, A., Frey, N. et al. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/35942626
Magnetic resonance imaging in a patient with cardiac resynchronization therapy-defibrillator and two abandoned leads. Lusebrink, E., Kaab, S. & Fichtner, S. J Arrhythm 38, 672-673 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35936043
Transcatheter Aortic Valve Replacement in a Patient With Criss-Cross Heart. Lewin, D., Van Praet, K. M., Nersesian, G., Kelm, M., Kofler, M., Baumgartner, M., Kempfert, J., Falk, V., Klein, C. & Unbehaun, A. JACC Case Rep 4, 934-940 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35935152
The effect of probiotic and synbiotic supplementation on lipid parameters among patients with cardiometabolic risk factors: a systematic review and meta-analysis of clinical trials. Ghorbani, Z., Kazemi, A., Bartolomaeus, T. U. P., Martami, F., Noormohammadi, M., Salari, A., Lober, U., Balou, H. A., Forslund, S. K. & Mahdavi-Roshan, M. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/35934838
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency. Sundaram, S. M., Arrulo Pereira, A., Muller-Fielitz, H., Kopke, H., De Angelis, M., Muller, T. D., Heuer, H., Korbelin, J., Krohn, M., Mittag, J., Nogueiras, R., Prevot, V. & Schwaninger, M. Brain145, 4264-4274 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35929549
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H., Ntalla, I., Hui, Q., Klarin, D. et al. Am J Hum Genet 109, 1366-1387 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35931049
Plasma levels of thrombin and activated protein C in patients with acute myocardial Infarction: An observational study. Becher, T., Schimanski, R., Muller, J., Baumann, S., Klenantz, S., Potzsch, B. & Lossnitzer, D. Int J Cardiol Heart Vasc 42, 101097 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35928794
Atrial functional assessment at rest and during exercise stress in left ventricular diastolic dysfunction. Backhaus, S. J. & Schuster, A. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35929610
Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies. Reichart, D., Lindberg, E. L., Maatz, H., Miranda, A. M. A., Viveiros, A., Shvetsov, N., Gartner, A., Nadelmann, E. R., Lee, M., Kanemaru, K., Ruiz-Orera, J., Strohmenger, V., DeLaughter, D. M., Patone, G., Zhang, H., Woehler, A., Lippert, C., Kim, Y., Adami, E., Gorham, J. M. et al. Science 377, eabo1984 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35926050
Coronary Access Following Redo TAVR: Impact of THV Design, Implant Technique, and Cell Misalignment. Meier, D., Akodad, M., Landes, U., Barlow, A. M., Chatfield, A. G., Lai, A., Tzimas, G., Tang, G. H. L., Puehler, T., Lutter, G., Leipsic, J. A., Sondergaard, L., Wood, D. A., Webb, J. G., Sellers, S. L. & Sathananthan, J. JACC Cardiovasc Interv 15, 1519-1531 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35926919
Neuro-oncological Ventral Antigen 2 Regulates Splicing of Vascular Endothelial Growth Factor Receptor 1 and Is Required for Endothelial Function. Kremer, V., Oppelaar, J. J., Gimbel, T., Koziarek, S., Ganzevoort, W., van Pampus, M. G., van den Born, B. J., Vogt, L., de Groot, C. & Boon, R. A. Reprod Sci(2022). https://www.ncbi.nlm.nih.gov/pubmed/35927413
Activation of an accessory pathway of glucose metabolism to treat dilated cardiomyopathy. Eschenhagen, T. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35923092
Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. Specker, E., Matthes, S., Wesolowski, R., Schutz, A., Grohmann, M., Alenina, N., Pleimes, D., Mallow, K., Neuenschwander, M., Gogolin, A., Weise, M., Pfeifer, J., Ziebart, N., Heinemann, U., von Kries, J. P., Nazare, M. & Bader, M. J Med Chem 65, 11126-11149 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35921615
Advanced diagnostics in inflammatory cardiomyopathy for personalized therapeutic decision-making. Schultheiss, H. P. & Escher, F. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35920154
A biomathematical model of atherosclerosis in mice. Schirm, S., Haghikia, A., Brack, M., Ahnert, P., Nouailles, G., Suttorp, N., Loeffler, M., Witzenrath, M. & Scholz, M. PLoS One 17, e0272079 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35921269
Le Coeur en Sabot: shape associations with adverse events in repaired tetralogy of Fallot. Mira, A., Lamata, P., Pushparajah, K., Abraham, G., Mauger, C. A., McCulloch, A. D., Omens, J. H., Bissell, M. M., Blair, Z., Huffaker, T., Tandon, A., Engelhardt, S., Koehler, S., Pickardt, T., Beerbaum, P., Sarikouch, S., Latus, H., Greil, G., Young, A. A. & Hussain, T. J Cardiovasc Magn Reson 24, 46 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35922806
Cardiac sarcoidosis: growing evidence in risk stratification. Meder, B. & Koelemen, J. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/35920166
Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients. Grunow, J. J., Reiher, K., Carbon, N. M., Engelhardt, L. J., Mai, K., Koch, S., Schefold, J. C., Z'Graggen, W., Schaller, S. J., Fielitz, J., Spranger, J., Weber-Carstens, S. & Wollersheim, T. Crit Care 26, 237 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35922829
Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities. Francis, C. M., Futschik, M. E., Huang, J., Bai, W., Sargurupremraj, M., Teumer, A., Breteler, M. M. B., Petretto, E., Ho, A. S. R., Amouyel, P., Engelter, S. T., Bulow, R., Volker, U., Volzke, H., Dorr, M., Imtiaz, M. A., Aziz, N. A., Lohner, V., Ware, J. S., Debette, S. et al. Nat Commun 13, 4505 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35922433
Follow-up of Patients With Stroke, Based on Opt-Out Choice Potential Approach for Acute Care Quality Registries or Observational Studies. Napierkowski, I., Lorenz-Meyer, I., Hille, A., Ebinger, M., Freitag, E., Harmel, P., Endres, M., Hagemann, G., Koennecke, H. C., Mackert, B. M., Siegerink, B., Audebert, H. J. & Berlin - Specific Acute Treatment in Ischemic or hAemorrhagic Stroke with Long-term follow-up, r. Neurology (2022). https://www.ncbi.nlm.nih.gov/pubmed/35918161
Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans. Lemmela, S., Wigmore, E. M., Benner, C., Havulinna, A. S., Ong, R. M. Y., Kempf, T., Wollert, K. C., Blankenberg, S., Zeller, T., Peters, J. E., Salomaa, V., Fritsch, M., March, R., Palotie, A., Daly, M., Butterworth, A. S., Kinnunen, M., Paul, D. S. & Matakidou, A. Elife 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35916366
Association of immune cell recruitment and BPD development. Heydarian, M., Schulz, C., Stoeger, T. & Hilgendorff, A. Mol Cell Pediatr 9, 16 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35917002
Percutaneous left atrial appendage occlusion in a frail, high-risk, octogenarian patient population, after having undergone transcatheter aortic valve implantation. Drosos, I., De Rosa, R., Cremer, S., Seppelt, P. C., Hemmann, K., Oppermann, J., Blessing, R., Mas-Peiro, S., Vasa-Nicotera, M., Zeiher, A. M. & Dimitriadis, Z. BMC Cardiovasc Disord 22, 349 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35918658
Beta-secretase-1 antisense RNA is associated with vascular ageing and atherosclerotic cardiovascular disease. Bampatsias, D., Mavroeidis, I., Tual-Chalot, S., Vlachogiannis, N. L., Bonini, F., Sachse, M., Mavraganis, G., Mareti, A., Kritsioti, C., Laina, A., Delialis, D., Ciliberti, G., Sopova, K., Gatsiou, A., Martelli, F., Georgiopoulos, G., Stellos, K. & Stamatelopoulos, K. Thromb Haemost (2022). https://www.ncbi.nlm.nih.gov/pubmed/35915966
Role of plant-based diets in promoting health and longevity. Herpich, C., Muller-Werdan, U. & Norman, K. Maturitas 165, 47-51 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35914402
Bail-Out Implantation of an Embolized Balloon-Expandable Transcatheter Heart Valve in the Aortic Arch Using Self-Expandable Stents. Dreger, H., Sundermann, S., Niehues, S. M. & Landmesser, U. Am J Cardiol 180, 163-164 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35914970
Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues. Santos, G. L., DeGrave, A. N., Rehman, A., Al Disi, S., Xhaxho, K., Schroder, H., Bao, G., Meyer, T., Tiburcy, M., Dworatzek, E., Zimmermann, W. H. & Lutz, S. Biomater Adv 139, 213041 (2022). https://www.ncbi.nlm.nih.gov/pubmed/35909053
September
Paper of the Month
(Epi)transcriptomics in cardiovascular and neurological complications of COVID-19. Jusic, A., Stellos, K., Ferreira, L., Baker, A. H. & Devaux, Y. J Mol Cell Cardiol Plus 1, 100013 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36164464
Effect of transcatheter edge-to-edge repair device position on diastolic hemodynamic parameters: An echocardiography-based simulation study. Vellguth, K., Barbieri, F., Reinthaler, M., Kasner, M., Landmesser, U., Kuehne, T., Hennemuth, A., Walczak, L. & Goubergrits, L. Front Cardiovasc Med 9, 915074 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36093164
Spinal Stroke: Outcome Attenuation by Erythropoietin and Carbamylated Erythropoietin and Its Prediction by Sphingosine-1-Phosphate Serum Levels in Mice. Koepke, L. G., Schwedhelm, E., Ibing, W., Oberhuber, A., Daum, G., Vcelar, B., Schelzig, H. & Simon, F. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36076955
SGLT2 Inhibitor Empagliflozin Modulates Ion Channels in Adult Zebrafish Heart. Karpushev, A. V., Mikhailova, V. B., Klimenko, E. S., Kulikov, A. N., Ivkin, D. Y., Kaschina, E. & Okovityi, S. V. Int J Mol Sci 23(2022). https://www.ncbi.nlm.nih.gov/pubmed/36076956
Cardiovascular magnetic resonance imaging patterns of acute COVID-19 mRNA vaccine-associated myocarditis in young male patients: A first single-center experience. Evertz, R., Schulz, A., Lange, T., Backhaus, S. J., Vollmann, D., Kowallick, J. T., von Haehling, S., Hasenfuss, G. & Schuster, A. Front Cardiovasc Med 9, 965512 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36082124
Assessment of the Consistency of Categorical Features Within the DZHK Biobanking Basic Set. Yusuf, K., Tahar, K., Sax, U., Hoffmann, W. & Krefting, D. Stud Health Technol Inform 296, 98-106 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36073494
Right ventricular dysfunction predicts outcome after transcatheter mitral valve repair for primary mitral valve regurgitation. Doldi, P. M., Stolz, L., Kalbacher, D., Koll, B., Geyer, M., Ludwig, S., Orban, M., Braun, D., Weckbach, L. T., Stocker, T. J., Nabauer, M., Higuchi, S., Ruf, T., Da Rocha, E. S. J., Wild, M., Tence, N., Unterhuber, M., Schofer, N., Petrescu, A., Thiele, H. et al. Eur J Heart Fail 24, 2162-2171 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36054557
Reference Interval for Serum L-Homoarginine Determined with Enzyme-Linked Immunosorbent Assay in the Population-Based Study of Health in Pomerania. Schwedhelm, E., Cordts, K., Moritz, E., Wesemann, R., Choe, C. U., Boger, R., Ittermann, T., Dorr, M., Friedrich, N. & Bahls, M. J Appl Lab Med 7, 1272-1282 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36172979
Aging-regulated TUG1 is dispensable for endothelial cell function. Gimbel, A. T., Koziarek, S., Theodorou, K., Schulz, J. F., Stanicek, L., Kremer, V., Ali, T., Günther, S., Kumar, S., Jo, H., Hübner, N., Maegdefessel, L., Dimmeler, S., van Heesch, S. & Boon, R. A. PLoS One 17, e0265160 (2022).
The developing epicardium regulates cardiac chamber morphogenesis by promoting cardiomyocyte growth. Boezio, G. L. M., Zhao, S., Gollin, J., Priya, R., Mansingh, S., Guenther, S., Fukuda, N., Gunawan, F. & Stainier, D. Y. R. Dis Model Mech 16 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36172839
Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial. Wolfrum, S., Roedl, K., Hanebutte, A., Pfeifer, R., Kurowski, V., Riessen, R., Daubmann, A., Braune, S., Soffker, G., Bibiza-Freiwald, E., Wegscheider, K., Schunkert, H., Thiele, H., Kluge, S. & Hypothermia After In-Hospital Cardiac Arrest Study, G. Circulation 146, 1357-1366 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36168956
Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations. Thareja, G., Belkadi, A., Arnold, M., Albagha, O. M. E., Graumann, J., Schmidt, F., Grallert, H., Peters, A., Gieger, C., Consortium, T. & Suhre, K. Hum Mol Genet (2022).
Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes. Mendez, P. L., Obendorf, L., Jatzlau, J., Burdzinski, W., Reichenbach, M., Nageswaran, V., Haghikia, A., Stangl, V., Hiepen, C. & Knaus, P. BMC Biol 20, 210 (2022).
Engineered CRISPR prime editors with compact, untethered reverse transcriptases. Grünewald, J., Miller, B. R., Szalay, R. N., Cabeceiras, P. K., Woodilla, C. J., Holtz, E. J. B., Petri, K. & Joung, J. K. Nat Biotechnol(2022).
Short-term effects of ultrafine particles on heart rate variability: A systematic review and meta-analysis. Zhang, S., Breitner, S., Pickford, R., Lanki, T., Okokon, E., Morawska, L., Samoli, E., Rodopoulou, S., Stafoggia, M., Renzi, M., Schikowski, T., Zhao, Q., Schneider, A. & Peters, A. Environ Pollut 314, 120245 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36162563
D(3) -Creatine dilution for body composition assessment: A direct take on the matter. Prado, C. M. & von Haehling, S. J Cachexia Sarcopenia Muscle 13, 2593-2594 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36156465
Characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis: A retrospective multicentre cohort study. Müller-Jensen, L., Zierold, S., Versluis, J. M., Boehmerle, W., Huehnchen, P., Endres, M., Mohr, R., Compter, A., Blank, C. U., Hagenacker, T., Meier, F., Reinhardt, L., Gesierich, A., Salzmann, M., Hassel, J. C., Ugurel, S., Zimmer, L., Banks, P., Spain, L., Soon, J. A. et al. European Journal of Cancer 175, 224-235 (2022).
[Use of a hypoglossal nerve stimulator during analgosedation in transcatheter aortic valve implantation]. Mayr, N. P., Pellegrini, C., Rheude, T. & Joner, M. Anaesthesiologie 71, 945-948 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36156159
Comparison of the predictive value of four insulin resistance surrogates for the prevalence of hypertension: a population-based study. Cheng, W., Kong, F. & Chen, S. Diabetology & Metabolic Syndrome 14, 137 (2022).
Sensitivity analyses for data missing at random versus missing not at random using latent growth modelling: a practical guide for randomised controlled trials. Staudt, A., Freyer-Adam, J., Ittermann, T., Meyer, C., Bischof, G., John, U. & Baumann, S. BMC Medical Research Methodology 22, 250 (2022).
The marantic kiss: potential novel pathognomonic echocardiographic sign of non-bacterial thrombotic endocarditis. Schneider, M., Frydas, A., Grubitzsch, H., Pieske, B. & Morris, D. A. Eur Heart J Cardiovasc Imaging 24, e19 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36151865
Methionine restriction - Association with redox homeostasis and implications on aging and diseases. Jelleschitz, J., Zhang, Y., Grune, T., Chen, W., Zhao, Y., Jia, M., Wang, Y., Liu, Z. & Hohn, A. Redox Biol 57, 102464 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36152485
Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT and is associated with pulmonary hypertension. Tian, S., Cai, Z., Sen, P., van Uden, D., van de Kamp, E., Thuillet, R., Tu, L., Guignabert, C., Boomars, K., Van der Heiden, K., Brandt, M. M. & Merkus, D. Am J Physiol Heart Circ Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36149769
Cardiovalve in mitral valve position-Additional solution for valve replacement. Sherif, M., Sundermann, S. H., Maisano, F., Pieske-Kraigher, E., Riess, J., Reinthaler, M., Mai, G. & Trippel, T. D. Front Cardiovasc Med 9, 960849 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36148056
Temporal trends in patients with peripheral artery disease influenced by diabetes mellitus in Germany. Schmitt, V. H., Hobohm, L., Vosseler, M., Brochhausen, C., Münzel, T., Espinola-Klein, C. & Keller, K. J Diabetes 14, 670-684 (2022).
In Vivo Skin Regeneration and Wound Healing Using Cell Micro-Transplantation. Nanic, L., Cedilak, A., Vidacek, N. S., Gruber, F., Huzak, M., Bader, M. & Rubelj, I. Pharmaceutics 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36145701
SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA. Maharana, S., Kretschmer, S., Hunger, S., Yan, X., Kuster, D., Traikov, S., Zillinger, T., Gentzel, M., Elangovan, S., Dasgupta, P., Chappidi, N., Lucas, N., Maser, K. I., Maatz, H., Rapp, A., Marchand, V., Chang, Y. T., Motorin, Y., Hubner, N., Hartmann, G. et al. Mol Cell (2022). https://www.ncbi.nlm.nih.gov/pubmed/36150385
Saturated Fatty Acid Blood Levels and Cardiometabolic Phenotype in Patients with HFpEF: A Secondary Analysis of the Aldo-DHF Trial. Lechner, K., von Schacky, C., Scherr, J., Lorenz, E., Bock, M., Lechner, B., Haller, B., Krannich, A., Halle, M., Wachter, R., Duvinage, A. & Edelmann, F. Biomedicines 10(2022). https://www.ncbi.nlm.nih.gov/pubmed/36140396
Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor. Fels, B., Beyer, A., Cazana-Perez, V., Giraldez, T., Navarro-Gonzalez, J. F., de la Rosa, D. A., Schaefer, F., Bayazit, A. K., Obrycki, L., Ranchin, B., Holle, J., Querfeld, U. & Kusche-Vihrog, K. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36142571
Performance of Marmoset Monkeys as Embryo Donors Is Reflected by Different Stress-Related Parameters. Drummer, C., Munzker, J., Heistermann, M., Becker, T., Missbach, S. & Behr, R. Animals (Basel)12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36139275
Association between the fatty liver index and chronic kidney disease: the population-based KORA study. Cai, X., Thorand, B., Hohenester, S., Koenig, W., Rathmann, W., Peters, A. & Nano, J. Nephrol Dial Transplant (2022). https://www.ncbi.nlm.nih.gov/pubmed/36150717
Albuminuria as a marker of systemic congestion in patients with heart failure. Boorsma, E. M., Ter Maaten, J. M., Damman, K., van Essen, B. J., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Dickstein, K., Metra, M., Filippatos, G., Lang, C. C., Ng, L., Anker, S. D., Cleland, J. G., Pellicori, P., Gansevoort, R. T., Heerspink, H. J. L., Voors, A. A. & Emmens, J. E. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36148485
Identification of the Transcription Factor ATF3 as a Direct and Indirect Regulator of the LDLR. Bauer, S., Eigenmann, J., Zhao, Y., Fleig, J., Hawe, J. S., Pan, C., Bongiovanni, D., Wengert, S., Ma, A., Lusis, A. J., Kovacic, J. C., Bjorkegren, J. L. M., Maegdefessel, L., Schunkert, H. & von Scheidt, M. Metabolites 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36144244
Impact of Elevated LDH on Cystatin C-Based Glomerular Filtration Rate Estimates in Patients with Cancer. Aydilek, E., Wallbach, M., Koziolek, M., Wulf, G. G. & Brokers, N. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36143104
Rotational Atherectomy or Balloon-Based Techniques to Prepare Severely Calcified Coronary Lesions. Rheude, T., Fitzgerald, S., Allali, A., Mashayekhi, K., Gori, T., Cuculi, F., Kufner, S., Hemetsberger, R., Sulimov, D. S., Rai, H., Ayoub, M., Bossard, M., Xhepa, E., Fusaro, M., Toelg, R., Joner, M., Byrne, R. A., Richardt, G., Kastrati, A., Cassese, S. et al. JACC Cardiovasc Interv 15, 1864-1874 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36137691
Obesity and cardiovascular disease: beyond body weight and energy balance. Lechner, K. & Krauss, R. M. Eur J Prev Cardiol 29, 2216-2217 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36136860
Incidence and impact of venous thromboembolism in hospitalized patients with Crohn's disease. Keller, K., Sivanathan, V., Schmitt, V. H., Ostad, M. A., Munzel, T., Espinola-Klein, C. & Hobohm, L. Thromb Res 219, 77-85 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36137330
No Matter How Slowly You Go as Long as You Do Not Stop. Kastrati, A. & Dibra, A. JACC Cardiovasc Interv 15, 1861-1863 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36137690
Fatigue and cognitive impairment after COVID-19: A prospective multicentre study. Hartung, T. J., Neumann, C., Bahmer, T., Chaplinskaya-Sobol, I., Endres, M., Geritz, J., Haeusler, K. G., Heuschmann, P. U., Hildesheim, H., Hinz, A., Hopff, S., Horn, A., Krawczak, M., Krist, L., Kudelka, J., Lieb, W., Maetzler, C., Mehnert-Theuerkauf, A., Montellano, F. A., Morbach, C. et al. EClinicalMedicine 53, 101651 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36133318
Conundrum of Classifying Subtypes of Pulmonary Hypertension-Introducing a Novel Approach to Classify "Borderline" Patients in a Population with Severe Aortic Stenosis Undergoing TAVI. Boxhammer, E., Gharibeh, S. X., Wernly, B., Kelm, M., Franz, M., Kretzschmar, D., Hoppe, U. C., Lauten, A. & Lichtenauer, M. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36135439
Lack of L-type amino acid transporter 2 in murine thyroid tissue induces autophagy. Venugopalan, V., Rehders, M., Weber, J., Rodermund, L., Al-Hashimi, A., Bargmann, T., Golchert, J., Reinecke, V., Homuth, G., Volker, U., Verrey, F., Kirstein, J., Heuer, H., Schweizer, U., Braun, D., Wirth, E. K. & Brix, K. J Mol Endocrinol 70 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36129170
Permanent pacemaker implantation and left bundle branch block with self-expanding valves - a SCOPE 2 subanalysis. Pellegrini, C., Garot, P., Morice, M. C., Tamburino, C., Bleiziffer, S., Thiele, H., Scholtz, S., Schramm, R., Cockburn, J., Cunnington, M., Wolf, A., Barbanti, M., Tchetche, D., Pagnotta, P., Gilard, M., Bedogni, F., Van Belle, E., Vasa-Nicotera, M., Chieffo, A., Bogaerts, K. et al. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/36128956
Pulsed-field ablation-based pulmonary vein isolation: acute safety, efficacy and short-term follow-up in a multi-center real world scenario. Lemoine, M. D., Fink, T., Mencke, C., Schleberger, R., My, I., Obergassel, J., Bergau, L., Sciacca, V., Rottner, L., Moser, J., Kany, S., Moser, F., Munkler, P., Dinshaw, L., Kirchhof, P., Reissmann, B., Ouyang, F., Sommer, P., Sohns, C., Rillig, A. et al. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36131138
Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders. El Andari, J., Renaud-Gabardos, E., Tulalamba, W., Weinmann, J., Mangin, L., Pham, Q. H., Hille, S., Bennett, A., Attebi, E., Bourges, E., Leborgne, C., Guerchet, N., Fakhiri, J., Kramer, C., Wiedtke, E., McKenna, R., Guianvarc'h, L., Toueille, M., Ronzitti, G., Hebben, M. et al. Sci Adv 8, eabn4704 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36129972
Catheter Ablation of Atrial Fibrillation in Patients With Heart Failure and Preserved Ejection Fraction. Zylla, M. M., Leiner, J., Rahm, A. K., Hoffmann, T., Lugenbiel, P., Schweizer, P., Scholz, E., Mereles, D., Kronsteiner, D., Kieser, M., Katus, H. A., Frey, N. & Thomas, D. Circ Heart Fail 15, e009281 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36126143
Atrial Functional Tricuspid Regurgitation: Novel Definition and Impact on Prognosis. Schlotter, F., Dietz, M. F., Stolz, L., Kresoja, K. P., Besler, C., Sannino, A., Rommel, K. P., Unterhuber, M., von Roeder, M., Delgado, V., Thiele, H., Hausleiter, J., Bax, J. J. & Lurz, P. Circ Cardiovasc Interv 15, e011958 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36126130
Modulatory role of gut microbiota in cholesterol and glucose metabolism: Potential implications for atherosclerotic cardiovascular disease. Roessler, J., Leistner, D. M., Landmesser, U. & Haghikia, A. Atherosclerosis 359, 1-12 (2022).
Non-invasive assessment of pulmonary vein isolation durability using late gadolinium enhancement magnetic resonance imaging. Padilla-Cueto, D., Ferro, E., Garre, P., Prat, S., Guichard, J. B., Perea, R. J., Tolosana, J. M., Guasch, E., Arbelo, E., Porta-Sanchez, A., Roca-Luque, I., Sitges, M., Brugada, J., Mont, L. & Althoff, T. F. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/36125227
Role of Cardiac Contractility Modulation in Heart Failure with a Higher Ejection Fraction. Talha, K. M., Anker, S. D., Burkhoff, D., Filippatos, G., Lam, C. S. P., Stone, G., Wazni, O. & Butler, J. J Card Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36122819
Challenges of the newer generation of resorbable magnesium scaffolds: Lessons from failure mechanisms of the past generation. Seguchi, M., Aytekin, A., Lenz, T., Nicol, P., Alvarez-Covarrubias, H. A., Xhepa, E., Klosterman, G. R., Beele, A., Sabic, E., Utsch, L., Alyaqoob, A. & Joner, M. J Cardiol 81, 179-188 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36122642
Association of Carotid Plaque and Flow Velocity With White Matter Integrity in a Middle-aged to Elderly Population. Rimmele, D. L., Petersen, E. L., Schlemm, E., Kessner, S. S., Petersen, M., Mayer, C., Cheng, B., Zeller, T., Waldeyer, C., Behrendt, C. A., Gerloff, C. & Thomalla, G. Neurology (2022). https://www.ncbi.nlm.nih.gov/pubmed/36123124
Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study. Kiel, M., Grabitz, S. D., Hopf, S., Koeck, T., Wild, P. S., Schmidtmann, I., Lackner, K. J., Munzel, T., Beutel, M. E., Pfeiffer, N. & Schuster, A. K. J Ophthalmol 2022, 9520512 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36119137
Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement. Kapadia, S. R., Makkar, R., Leon, M., Abdel-Wahab, M., Waggoner, T., Massberg, S., Rottbauer, W., Horr, S., Sondergaard, L., Karha, J., Gooley, R., Satler, L., Stoler, R. C., Messe, S. R., Baron, S. J., Seeger, J., Kodali, S., Krishnaswamy, A., Thourani, V. H., Harrington, K. et al. N Engl J Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/36121045
No evidence for age-related alterations in the marmoset retina. Haverkamp, S., Reinhard, K., Peichl, L. & Mietsch, M. Front Neuroanat 16, 945295 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36120100
Sex-specific impact of anthropometric parameters on outcomes after transcatheter edge-to-edge repair for secondary mitral regurgitation. Higuchi, S., Orban, M., Adamo, M., Giannini, C., Melica, B., Karam, N., Praz, F., Kalbacher, D., Lubos, E., Stolz, L., Braun, D., Nabauer, M., Wild, M., Doldi, P., Neuss, M., Butter, C., Kassar, M., Ruf, T., Petrescu, A., Schofer, N. et al. Int J Cardiol 371, 312-318 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36115443
Calcium in peroxisomes: An essential messenger in an essential cell organelle. Sargsyan, Y., Kalinowski, J. & Thoms, S. Front Cell Dev Biol 10, 992235 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36111338
Heart failure during the COVID-19 pandemic: clinical, diagnostic, management, and organizational dilemmas. Palazzuoli, A., Metra, M., Collins, S. P., Adamo, M., Ambrosy, A. P., Antohi, L. E., Ben Gal, T., Farmakis, D., Gustafsson, F., Hill, L., Lopatin, Y., Tramonte, F., Lyon, A., Masip, J., Miro, O., Moura, B., Mullens, W., Radu, R. I., Abdelhamid, M., Anker, S. et al. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36111511
Cross-sectional study on the association of periodontitis with arterial hypertension in the Hamburg City Health Study. Konnecke, H., Schnabel, R. B., Walther, C., Lamprecht, R., Heydecke, G., Seedorf, U., Jagodzinski, A., Borof, K., Zeller, T., Beikler, T., Smeets, R., Gosau, M., Behrendt, C. A., Wenzel, U., Borschel, C. S., Karakas, M., Blankenberg, S. & Aarabi, G. Eur J Med Res 27, 181 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36114562
Sex-specific associations of cardiorespiratory fitness and galectin-3 in the general population. Haid, M. E., Zylla, S., Paulista Markus, M. R., Friedrich, N., Ewert, R., Glaser, S., Felix, S. B., Dorr, M. & Bahls, M. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36113868
Comparison of hemodynamics in biological surgical aortic valve replacement and transcatheter aortic valve implantation - an in-silico study. Franke, B., Schlief, A., Walczak, L., Sundermann, S., Unbehaun, A., Kempfert, J., Solowjowa, N., Kuhne, T. & Goubergrits, L. Artif Organs (2022). www.ncbi.nlm.nih.gov/pubmed/36114598
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes. Seibertz, F., Rapedius, M., Fakuade, F. E., Tomsits, P., Liutkute, A., Cyganek, L., Becker, N., Majumder, R., Clauss, S., Fertig, N. & Voigt, N. Commun Biol 5, 969 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36109584
Photon-counting detector CT improves quality of arterial phase abdominal scans: A head-to-head comparison with energy-integrating CT. Graafen, D., Muller, L., Halfmann, M., Duber, C., Hahn, F., Yang, Y., Emrich, T. & Kloeckner, R. Eur J Radiol 156, 110514 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36108479
Association between periodontitis and heart failure in the general population. Walther, C., Wenzel, J. P., Schnabel, R. B., Heydecke, G., Seedorf, U., Beikler, T., Borof, K., Nikorowitsch, J., Schrage, B., Blankenberg, S., Twerenbold, R., Zeller, T., Magnussen, C. & Aarabi, G. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36101477
Early effect of thrombolysis on structural brain network organisation after anterior-circulation stroke in the randomized WAKE-UP trial. Schlemm, E., Jensen, M., Kuceyeski, A., Jamison, K., Ingwersen, T., Mayer, C., Konigsberg, A., Boutitie, F., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Galinovic, I., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Puig, J., Simonsen, C. Z., Thijs, V. et al. Hum Brain Mapp 43, 5053-5065 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36102287
Percutaneous Left Atrial Appendage Closure with the LAmbre Device Protected by a Cerebral Protection System in a 76-Year-Old Man with Persistent Left Atrial Appendage Thrombus. Popescu, S. S., Heeger, C. H., Keelani, A. & Tilz, R. R. Am J Case Rep 23, e937063 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36101478
The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function. Nitz, K., Lacy, M., Bianchini, M., Wichapong, K., Kucukgoze, I. A., Bonfiglio, C. A., Migheli, R., Wu, Y., Burger, C., Li, Y., Forne, I., Ammar, C., Janjic, A., Mohanta, S., Duchene, J., Heemskerk, J. W. M., Megens, R. T. A., Schwedhelm, E., Huveneers, S., Lygate, C. A. et al. Circ Res, 101161CIRCRESAHA122321094 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36102188
Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease. Wollenhaupt, J., Frisch, J., Harlacher, E., Wong, D. W. L., Jin, H., Schulte, C., Vondenhoff, S., Moellmann, J., Klinkhammer, B. M., Zhang, L., Baleanu-Curaj, A., Liehn, E. A., Speer, T., Kazakov, A., Werner, C., van der Vorst, E. P. C., Selejan, S. R., Hohl, M., Bohm, M., Kramann, R. et al. Redox Biol 56, 102459 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36099852
How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from the European Association of Preventive Cardiology (EAPC). Pedretti, R. F. E., Hansen, D., Ambrosetti, M., Back, M., Berger, T., Ferreira, M. C., Cornelissen, V., Davos, C. H., Doehner, W., de Pablo, Y. Z. C., Frederix, I., Greco, A., Kurpas, D., Michal, M., Osto, E., Pedersen, S., Salvador, R. E., Simonenko, M., Steca, P., Thompson, D. R.et al. Eur J Prev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36098041
Discrepancy of echocardiography and computed tomography in initial assessment and 2-year follow-up for monitoring Marfan syndrome and related disorders. Beetz, N. L., Trippel, T. D., Philipp, K., Maier, C., Walter-Rittel, T., Shnayien, S. & Gehle, P. Sci Rep 12, 15333 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36097197
Comparison of cine cardiac magnetic resonance and echocardiography derived diameters of the aortic root in a large population-based cohort. Wenzel, J. P., Nikorowitsch, J., Bei der Kellen, R., Dohm, L., Girdauskas, E., Lund, G., Bannas, P., Blankenberg, S., Kolbel, T., Cavus, E., Mullerleile, K., Kaul, M. G., Adam, G. & Weinrich, J. M. Sci Rep 12, 15307 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36096919
CXCR4 and CD74 together enhance cell survival in response to macrophage migration-inhibitory factor in chronic lymphocytic leukemia. Thavayogarajah, T., Sinitski, D., El Bounkari, O., Torres-Garcia, L., Lewinsky, H., Harjung, A., Chen, H. R., Panse, J., Vankann, L., Shachar, I., Bernhagen, J. & Koschmieder, S. Exp Hematol 115, 30-43 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36096455
Temporal trends in incidence, patient characteristics, microbiology and in-hospital mortality in patients with infective endocarditis: a contemporary analysis of 86,469 cases between 2007 and 2019. Becher, P. M., Gossling, A., Fluschnik, N., Schrage, B., Seiffert, M., Schofer, N., Blankenberg, S., Kirchhof, P., Westermann, D. & Kalbacher, D. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36094574
Insulin-like growth factor binding protein 7 (IGFBP7), a link between heart failure and senescence. Bracun, V., van Essen, B., Voors, A. A., van Veldhuisen, D. J., Dickstein, K., Zannad, F., Metra, M., Anker, S., Samani, N. J., Ponikowski, P., Filippatos, G., Cleland, J. G. F., Lang, C. C., Ng, L. L., Shi, C., de Wit, S., Aboumsallem, J. P., Meijers, W. C., Klip, I. T., van der Meer, P. et al. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36088651
Heart failure outcomes according to heart rate and effects of empagliflozin in patients of the EMPEROR-Preserved Trial. Bohm, M., Butler, J., Mahfoud, F., Filippatos, G., Ferreira, J. P., Pocock, S. J., Slawik, J., Brueckmann, M., Linetzky, B., Schuler, E., Wanner, C., Zannad, F., Packer, M., Anker, S. D., Committees, E. M.-P. T. & Investigators. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36087309
PCSK9 Inhibitor Wars: How Does Inclisiran Fit in with Current Monoclonal Antibody Inhibitor Therapy? Considerations for Patient Selection. Arnold, N. & Koenig, W. Curr Cardiol Rep (2022). https://www.ncbi.nlm.nih.gov/pubmed/36087240
ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes. Zech, A. T. L., Prondzynski, M., Singh, S. R., Pietsch, N., Orthey, E., Alizoti, E., Busch, J., Madsen, A., Behrens, C. S., Meyer-Jens, M., Mearini, G., Lemoine, M. D., Kramer, E., Mosqueira, D., Virdi, S., Indenbirken, D., Depke, M., Salazar, M. G., Volker, U., Braren, I. et al. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36078153
Distress-Mediated Remodeling of Cardiac Connexin-43 in a Novel Cell Model for Arrhythmogenic Heart Diseases. Wahl, C. M., Schmidt, C., Hecker, M. & Ullrich, N. D. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36077591
European Stroke Organisation (ESO) guideline on screening for subclinical atrial fibrillation after stroke or transient ischaemic attack of undetermined origin. Rubiera, M., Aires, A., Antonenko, K., Lemeret, S., Nolte, C. H., Putaala, J., Schnabel, R. B., Tuladhar, A. M., Werring, D. J., Zeraatkar, D. & Paciaroni, M. Eur Stroke J 7, VI (2022). https://www.ncbi.nlm.nih.gov/pubmed/36082257
Quantitative Phosphoproteomics of the Angiotensin AT(2)-Receptor Signaling Network Identifies HDAC1 (Histone-Deacetylase-1) and p53 as Mediators of Antiproliferation and Apoptosis. Peluso, A. A. B., Kempf, S. J., Verano-Braga, T., Rodrigues-Ribeiro, L., Johansen, L. E., Hansen, M. R., Kitlen, G., Haugaard, A. H., Sumners, C., Ditzel, H. J., Santos, R. A., Bader, M., Larsen, M. R. & Steckelings, U. M. Hypertension, 101161hypertensionaha12118620 (2022).
Reciprocal abrogation of PKM isoforms: contradictory outcomes and differing impact of splicing signal on CRISPR/Cas9 mediates gene editing in keratinocytes. Nold, S. P., Sych, K., Imre, G., Fuhrmann, D. C., Pfeilschifter, J., Vutukuri, R., Schnutgen, F., Wittig, I., Meisterknecht, J., Frank, S. & Goren, I. FEBS J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36083715
Mediterranean Diet and Atrial Fibrillation: Lessons Learned from the AFHRI Case-Control Study. Neumann, F. A., Jagemann, B., Makarova, N., Borschel, C. S., Aarabi, G., Gutmann, F., Schnabel, R. B. & Zyriax, B. C. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36079872
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis. Brandenburg, S., Drews, L., Schonberger, H. L., Jacob, C. F., Paulke, N. J., Beuthner, B. E., Topci, R., Kohl, T., Neuenroth, L., Kutschka, I., Urlaub, H., Kuck, F., Leha, A., Friede, T., Seidler, T., Jacobshagen, C., Toischer, K., Puls, M., Hasenfuss, G., Lenz, C. et al. J Mol Cell Cardiol 173, 1-15 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36084744
Exercise for Primary and Secondary Prevention of Cardiovascular Disease: JACC Focus Seminar 1/4. Tucker, W. J., Fegers-Wustrow, I., Halle, M., Haykowsky, M. J., Chung, E. H. & Kovacic, J. C. J Am Coll Cardiol80, 1091-1106 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36075680
Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury. Studemann, T., Rossinger, J., Manthey, C., Geertz, B., Srikantharajah, R., von Bibra, C., Shibamiya, A., Kohne, M., Wiehler, A., Wiegert, J. S., Eschenhagen, T. & Weinberger, F. Circulation, 101161CIRCULATIONAHA122060124 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36073365
Individual Patient Data Meta-analysis of Drug-eluting Versus Bare-metal Stents for Percutaneous Coronary Intervention in Chronic Versus Acute Coronary Syndromes. Piccolo, R., Bonaa, K. H., Efthimiou, O., Varenne, O., Baldo, A., Urban, P., Kaiser, C., de Belder, A., Lemos, P. A., Wilsgaard, T., Reifart, J., Ribeiro, E. E., Serruys, P. W., Byrne, R. A., de la Torre Hernandez, J. M., Esposito, G., Wijns, W., Juni, P., Windecker, S., Valgimigli, M. et al. Am J Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36075755
Fractal Analysis of Dynamic Stress CT-Perfusion Imaging for Detection of Hemodynamically Relevant Coronary Artery Disease. Michallek, F., Nakamura, S., Kurita, T., Ota, H., Nishimiya, K., Ogawa, R., Shizuka, T., Nakashima, H., Wang, Y., Ito, T., Sakuma, H., Dewey, M. & Kitagawa, K. JACC Cardiovasc Imaging 15, 1591-1601 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36075619
Propensity matched comparison of TAVI and SAVR in intermediate-risk patients with severe aortic stenosis and moderate-to-severe chronic kidney disease: a subgroup analysis from the German Aortic Valve Registry. Mas-Peiro, S., Faerber, G., Bon, D., Herrmann, E., Bauer, T., Bleiziffer, S., Bekeredjian, R., Boning, A., Frerker, C., Beckmann, A., Mollmann, H., Ensminger, S., Hamm, C. W., Beyersdorf, F., Fichtlscherer, S., Walther, T. & Board, G. A.-E. Clin Res Cardiol 111, 1387-1395 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36074270
Protein Tyrosine Phosphatase 1B Deficiency in Vascular Smooth Muscle Cells Promotes Perivascular Fibrosis following Arterial Injury. Gogiraju, R., Gachkar, S., Velmeden, D., Bochenek, M. L., Zifkos, K., Hubert, A., Munzel, T., Offermanns, S. & Schafer, K. Thromb Haemost 122, 1814-1826 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36075234
Biomarkers in heart failure clinical trials. A review from the Biomarkers Working Group of the Heart Failure Association of the European Society of Cardiology. Bayes-Genis, A., Aimo, A., Jhund, P., Richards, M., de Boer, R. A., Arfsten, H., Fabiani, I., Lupon, J., Anker, S. D., Gonzalez, A., Castiglione, V., Metra, M., Mueller, C., Nunez, J., Rossignol, P., Barison, A., Butler, J., Teerlink, J., Filippatos, G., Ponikowski, P. et al. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36073112
Multimodality Imaging to Assess Leaflet Height in Mitral Bioprosthetic Valves: Implications for Mitral Valve-in-Valve Procedure. Akodad, M., Sathananthan, J., Tzimas, G., Salcudean, H., Hensey, M., Gulsin, G. S., Meier, D., Anthony Chuang, M. Y., Chatfield, A. G., Landes, U., Blanke, P., Sondergaard, L., Payne, G. W., Lutter, G., Puehler, T., Wood, D. A., Webb, J. G., Leipsic, J. A. & Sellers, S. L. JACC Cardiovasc Imaging 15, 1663-1665 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36075626
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. et al. Nat Genet 54, 1332-1344 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36071172
Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Li, X., Delerue, T., Schottker, B., Holleczek, B., Grill, E., Peters, A., Waldenberger, M., Thorand, B. & Brenner, H. Nat Commun 13, 5269 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36071044
Survival benefit of overweight patients undergoing MitraClip(R) procedure in comparison to normal-weight patients. Keller, K., Geyer, M., Hobohm, L., Tamm, A. R., Kreidel, F., Ruf, T. F., Hell, M., Schmitt, V. H., Bachmann, K., Born, S., Schulz, E., Munzel, T. & von Bardeleben, R. S. Clin Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36070481
Evaluation of the HFA-PEFF Score: results from the prospective DIAST-CHF cohort. Hashemi, D., Mende, M., Trippel, T. D., Petutschnigg, J., Hasenfuss, G., Nolte, K., Herrmann-Lingen, C., Feuerstein, A., Langhammer, R., Tschope, C., Pieske, B., Wachter, R. & Edelmann, F. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36070881
European Society of Cardiology Quality Indicators for the Cardiovascular Preoperative Assessment and Management of patients considered for non-cardiac surgery. Developed in collaboration with the European Society of Anaesthesiology & Intensive Care. Gencer, B., Gale, C. P., Aktaa, S., Halvorsen, S., Beska, B., Abdelhamid, M., Mueller, C., Tutarel, O., McGreavy, P., Schirmer, H., Geissler, T., Sillesen, H., Niessner, A., Zacharowski, K., Mehilli, J. & Potpara, T. Eur Heart J Qual Care Clin Outcomes (2022). https://www.ncbi.nlm.nih.gov/pubmed/36069905
Targeting innate immunity-driven inflammation in CKD and cardiovascular disease. Speer, T., Dimmeler, S., Schunk, S. J., Fliser, D. & Ridker, P. M. Nat Rev Nephrol 18, 762-778 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36064794
In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice. Rovai, A., Chung, B., Hu, Q., Hook, S., Yuan, Q., Kempf, T., Schmidt, F., Grimm, D., Talbot, S. R., Steinbruck, L., Gotting, J., Bohne, J., Krooss, S. A. & Ott, M. Nat Commun 13, 5215 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36064805
Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions. Paulus, M. G., Renner, K., Nickel, A. G., Brochhausen, C., Limm, K., Zugner, E., Baier, M. J., Pabel, S., Wallner, S., Birner, C., Luchner, A., Magnes, C., Oefner, P. J., Stark, K. J., Wagner, S., Maack, C., Maier, L. S., Streckfuss-Bomeke, K., Sossalla, S. & Dietl, A. Basic Res Cardiol 117, 45 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36068416
Dyskalemia in people at increased risk for heart failure: findings from the heart 'OMics' in AGEing (HOMAGE) trial. Monzo, L., Ferreira, J. P., Cleland, J. G. F., Pellicori, P., Mariottoni, B., Hazebroek, M. R., Collier, T. J., Cuthbert, J. J., Pieske, B., Petutschnigg, J., Ahmed, F. Z., Girerd, N., Clark, A. L., Cosmi, F., Staessen, J. A., Heymans, S., Rossignol, P. & Zannad, F. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36065795
Chronic cigarette smoking is associated with increased arterial stiffness in men and women: evidence from a large population-based cohort. Hahad, O., Schmitt, V. H., Arnold, N., Keller, K., Prochaska, J. H., Wild, P. S., Schulz, A., Lackner, K. J., Pfeiffer, N., Schmidtmann, I., Michal, M., Schattenberg, J. M., Tuscher, O., Daiber, A. & Munzel, T. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36068365
Forebrain corticosteroid receptors promote post-myocardial infarction depression and mortality. Bruns, B., Daub, R., Schmitz, T., Hamze-Sinno, M., Spaich, S., Dewenter, M., Schwale, C., Gass, P., Vogt, M., Katus, H., Herzog, W., Friederich, H. C., Frey, N., Schultz, J. H. & Backs, J. Basic Res Cardiol 117, 44 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36068417
The Role of Sex and Age in Moderating the Outcome of In-Person and Computer-Based Brief Alcohol Interventions at General Hospitals: Reanalysis of a Brief Intervention Study. Baumann, S., Gaertner, B., Bischof, G., Krolo, F., John, U. & Freyer-Adam, J. Eur Addict Res, 1-7 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36067728
A head-to-head comparison of fast-SENC and feature tracking to LV long axis strain for assessment of myocardial deformation in chest pain patients. Siry, D., Riffel, J., Salatzki, J., Andre, F., Weberling, L. D., Ochs, M., Atia, N. A., Hillier, E., Albert, D., Katus, H. A., Giannitsis, E., Frey, N. & Friedrich, M. G. BMC Med Imaging 22, 159 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36064332
Long-term cardiac pathology in individuals with mild initial COVID-19 illness. Puntmann, V. O., Martin, S., Shchendrygina, A., Hoffmann, J., Ka, M. M., Giokoglu, E., Vanchin, B., Holm, N., Karyou, A., Laux, G. S., Arendt, C., De Leuw, P., Zacharowski, K., Khodamoradi, Y., Vehreschild, M., Rohde, G., Zeiher, A. M., Vogl, T. J., Schwenke, C. & Nagel, E. Nat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/36064600
Paediatric familial hypercholesterolaemia screening in Europe: public policy background and recommendations. Gidding, S. S., Wiegman, A., Groselj, U., Freiberger, T., Peretti, N., Dharmayat, K. I., Daccord, M., Bedlington, N., Sikonja, J., Ray, K. K., Santos, R. D., Halle, M., Tokgozoglu, L., Gutierrez-Ibarluzea, I., Pinto, F. J. & Geanta, M. Eur J Prev Cardiol 29, 2301-2311 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36059237
Sleep apnea predicts cardiovascular death in patients with Marfan syndrome: a cohort study. Gessler, N., Wohlmuth, P., Anwar, O., Debus, E. S., Eickholt, C., Gunawardene, M. A., Hakmi, S., Heitmann, K., Rybczynski, M., Schueler, H., Sheikhzadeh, S., Tigges, E., Wiest, G. H., Willems, S., Adam, E. & von Kodolitsch, Y. EPMA J 13, 451-460 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36061830
Cardiac screening prior to return to play after SARS-CoV-2 infection: focus on the child and adolescent athlete: A Clinical Consensus Statement of the Task Force for Childhood Health of the European Association of Preventive Cardiology. D'Ascenzi, F., Castelletti, S., Adami, P. E., Cavarretta, E., Sanz-de la Garza, M., Maestrini, V., Biffi, A., Kantor, P., Pieles, G., Verhagen, E., Tiberi, M., Hanssen, H., Papadakis, M., Niebauer, J. & Halle, M. Eur J Prev Cardiol 29, 2120-2124 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36059208
Circadian cardiac NAD(+) metabolism, from transcriptional regulation to healthy aging. Carpenter, B. J. & Dierickx, P. Am J Physiol Cell Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36062878
Stroke-Heart Syndrome: Recent Advances and Challenges. Scheitz, J. F., Sposato, L. A., Schulz-Menger, J., Nolte, C. H., Backs, J. & Endres, M. J Am Heart Assoc 11, e026528 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36056731
Identification of risk loci for primary aldosteronism in genome-wide association studies. Le Floch, E., Cosentino, T., Larsen, C. K., Beuschlein, F., Reincke, M., Amar, L., Rossi, G. P., De Sousa, K., Baron, S., Chantalat, S., Saintpierre, B., Lenzini, L., Frouin, A., Giscos-Douriez, I., Ferey, M., Abdellatif, A. B., Meatchi, T., Empana, J. P., Jouven, X., Gieger, C. et al. Nat Commun 13, 5198 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36057693
Should HFrEF patients with NYHA class II expect benefit from CCM therapy? Results from the MAINTAINED observational study. Fastner, C., Yuecel, G., Hetjens, S., Rudic, B., Schmiel, G., Toepel, M., Liebe, V., Kruska, M., Borggrefe, M., Burkhoff, D., Akin, I., Duerschmied, D. & Kuschyk, J. Clin Res Cardiol 111, 1286-1294 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36056955
Looking into the future of ACS patients through the small OCT window. Aytekin, A. & Kastrati, A. Rev Esp Cardiol (Engl Ed) (2022). https://www.ncbi.nlm.nih.gov/pubmed/36057426
The dawn has come for new therapeutics to treat atherosclerosis: Targeting neuroimmune cardiovascular interfaces in artery brain circuits. Mohanta, S. K., Weber, C., Yin, C. & Habenicht, A. J. R. Clin Transl Med 12, e1040 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36052959
Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement. Kaiyrzhanov, R., Mohammed, S. E. M., Maroofian, R., Husain, R. A., Catania, A., Torraco, A., Alahmad, A., Dutra-Clarke, M., Gronborg, S., Sudarsanam, A., Vogt, J., Arrigoni, F., Baptista, J., Haider, S., Feichtinger, R. G., Bernardi, P., Zulian, A., Gusic, M., Efthymiou, S., Bai, R.et al. Am J Hum Genet 109, 1692-1712 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36055214
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J. W., Haessler, J., Lyytikainen, L. P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S. et al. Nat Commun 13, 5144 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36050321
Cathepsin S Levels and Survival Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes. Stamatelopoulos, K., Mueller-Hennessen, M., Georgiopoulos, G., Lopez-Ayala, P., Sachse, M., Vlachogiannis, N. I., Sopova, K., Delialis, D., Bonini, F., Patras, R., Ciliberti, G., Vafaie, M., Biener, M., Boeddinghaus, J., Nestelberger, T., Koechlin, L., Tual-Chalot, S., Kanakakis, I., Gatsiou, A., Katus, H. et al. J Am Coll Cardiol 80, 998-1010 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36049808
Mammalian Target of Rapamycin Inhibition in Patients With ST-Segment Elevation Myocardial Infarction. Stahli, B. E., Klingenberg, R., Heg, D., Branca, M., Manka, R., Kapos, I., Muggler, O., Denegri, A., Kesterke, R., Berger, F., Stehli, J., Candreva, A., von Eckardstein, A., Carballo, D., Hamm, C., Landmesser, U., Mach, F., Moccetti, T., Jung, C., Kelm, M. et al. J Am Coll Cardiol 80, 1802-1814 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36049557
Monitoring for atrial fibrillation prior to patent foramen ovale closure after cryptogenic stroke. Diener, H. C., Wachter, R., Wong, A., Thijs, V., Schnabel, R. B., Ntaios, G., Kasner, S., Rothwell, P. M., Passman, R., Saver, J. L., Albers, B. A. & Bernstein, R. A. Int J Stroke, 17474930221124412 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36050817
Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. Mattonet, K., Riemslagh, F. W., Guenther, S., Prummel, K. D., Kesavan, G., Hans, S., Ebersberger, I., Brand, M., Burger, A., Reischauer, S., Mosimann, C. & Stainier, D. Y. R. Sci Adv 8, eabn2082 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36044573
Effects of homoarginine supplementation on heart and skeletal muscle of rats with heart failure with preserved ejection fraction. Buttner, P., Adams, V., Werner, S., Ossmann, S., Besler, C., Schwedhelm, E. & Thiele, H. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36043453
Oktober
Paper of the Month
Cardiac Thrombogenicity in Stroke: Mechanisms and Evaluation. Back, M. & Doehner, W. Eur J Vasc Endovasc Surg 64, 150-152 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36309461
The C1q-ApoE complex: A new hallmark pathology of viral hepatitis and nonalcoholic fatty liver disease. Habenicht, L. K. L., Wang, Z., Zhang, X., Li, Y., Mogler, C., Huspenina, J. S., Schmid, R. M., Weber, C., Mohanta, S. K., Ma, Z. & Yin, C. Front Immunol 13, 970938 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36304458
Editorial: Cardiac optogenetics: Using light to observe and excite the heart. Bruegmann, T., Smith, G. L. & Lehnart, S. E. Front Physiol 13, 1031062 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36304575
Reduction in SOCE and Associated Aggregation in Platelets from Mice with Platelet-Specific Deletion of Orai1. Yang, L., Ottenheijm, R., Worley, P., Freichel, M. & Camacho Londono, J. E. Cells 11(2022). https://www.ncbi.nlm.nih.gov/pubmed/36291093
Mobilization of CD11b(+)/Ly6c(hi) monocytes causes multi organ dysfunction syndrome in acute pancreatitis. Wilden, A., Glaubitz, J., Otto, O., Biedenweg, D., Nauck, M., Mack, M., Ribback, S., Broker, B. M., von Rheinbaben, S. F., Lerch, M. M., Aghdassi, A. A., Weiss, F. U. & Sendler, M. Front Immunol 13, 991295 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36300116
Intraocular Pressure-Induced Endothelial Dysfunction of Retinal Blood Vessels Is Persistent, but Does Not Trigger Retinal Ganglion Cell Loss. Wang, M., Liu, H., Xia, N., Li, H., van Beers, T., Gericke, A. & Prokosch, V. Antioxidants (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36290587
High Temporal Resolution Dual-Source Photon-Counting CT for Coronary Artery Disease: Initial Multicenter Clinical Experience. Soschynski, M., Hagen, F., Baumann, S., Hagar, M. T., Weiss, J., Krauss, T., Schlett, C. L., von Zur Muhlen, C., Bamberg, F., Nikolaou, K., Greulich, S., Froelich, M. F., Riffel, P., Overhoff, D., Papavassiliu, T., Schoenberg, S. O., Faby, S., Ulzheimer, S., Ayx, I. & Krumm, P. J Clin Med 11(2022). https://www.ncbi.nlm.nih.gov/pubmed/36294324
Genotype Complements the Phenotype: Identification of the Pathogenicity of an LMNA Splice Variant by Nanopore Long-Read Sequencing in a Large DCM Family. Sedaghat-Hamedani, F., Rebs, S., Kayvanpour, E., Zhu, C., Amr, A., Muller, M., Haas, J., Wu, J., Steinmetz, L. M., Ehlermann, P., Streckfuss-Bomeke, K., Frey, N. & Meder, B. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36293084
Left Ventricular Assist Device Implantation in Cancer-Therapy-Related Heart Failure. Mulzer, J., Muller, M., Schoenrath, F., Falk, V., Potapov, E. & Knierim, J. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36294920
Blockade of Wnt Secretion Attenuates Myocardial Ischemia-Reperfusion Injury by Modulating the Inflammatory Response. Meyer, I. S., Li, X., Meyer, C., Voloshanenko, O., Pohl, S., Boutros, M., Katus, H. A., Frey, N. & Leuschner, F. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36293109
COVID-19 Infections in Adults with Congenital Heart Disease-A Prospective Single-Center Study in an Outpatient Setting. Langes, N., Meierhofer, C., Nagdyman, N., Maurer, S. J., Bourier, F., Halle, M., Holdenrieder, S., Ewert, P. & Tutarel, O. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36294426
Long-Term Psychosocial Consequences of Whole-Body Magnetic Resonance Imaging and Reporting of Incidental Findings in a Population-Based Cohort Study. Korbmacher-Bottcher, D., Bamberg, F., Peters, A., Linkohr, B., Ladwig, K. H., Schwettmann, L., Weckbach, S., Schlett, C. L. & Rospleszcz, S. Diagnostics (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36292045
Cluster Analysis Statistical Spectroscopy for the Identification of Metabolites in (1)H NMR Metabolomics. Heinzmann, S. S., Waldenberger, M., Peters, A. & Schmitt-Kopplin, P. Metabolites 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36295894
Effects of an Omega-3 Supplemented, High-Protein Diet in Combination with Vibration and Resistance Exercise on Muscle Power and Inflammation in Old Adults: A Pilot Randomized Controlled Trial. Hass, U., Kochlik, B., Herpich, C., Rudloff, S. & Norman, K. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36296958
Frequency, Risk Factors, and Clinical Outcomes of Late-Onset Atrial Flutter in Patients after Heart Transplantation. Rahm, A. K., Reinhardt, S., Helmschrott, M., Darche, F. F., Bruckner, T., Lugenbiel, P., Thomas, D., Ehlermann, P., Sommer, W., Warnecke, G., Frey, N. & Rivinius, R. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36286289
Iatrogenic atrial septal defects after transseptal puncture for percutaneous left atrial appendage occlusion and their hemodynamic effects. Drosos, I., Rosa, R., Seppelt, P. C., Cremer, S., Mas-Peiro, S., Hemmann, K., Oppermann, J., Blessing, R., Vasa-Nicotera, M., Zeiher, A. M. & Dimitriadis, Z. J Geriatr Cardiol19, 675-684 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36284683
High-throughput optical action potential recordings in hiPSC-derived cardiomyocytes with a genetically encoded voltage indicator in the AAVS1 locus. Zhang, F., Meier, A. B., Poch, C. M., Tian, Q., Engelhardt, S., Sinnecker, D., Lipp, P., Laugwitz, K. L., Moretti, A. & Dorn, T. Front Cell Dev Biol 10, 1038867 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36274846
Microcephaly is associated with impaired educational development in children with congenital heart disease. Pfitzer, C., Sievers, L. K., Hutter, A., Khaliq, H. A., Poryo, M., Berger, F., Bauer, U. M. M., Helm, P. C. & Schmitt, K. R. L. Front Cardiovasc Med 9, 917507 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36277771
Pulmonary hypertension: Linking inflammation and pulmonary arterial stiffening. Liu, S. F., Nambiar Veetil, N., Li, Q., Kucherenko, M. M., Knosalla, C. & Kuebler, W. M. Front Immunol 13, 959209 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36275740
A mechanistic framework for cardiometabolic and coronary artery diseases. Koplev, S., Seldin, M., Sukhavasi, K., Ermel, R., Pang, S., Zeng, L., Bankier, S., Di Narzo, A., Cheng, H., Meda, V., Ma, A., Talukdar, H., Cohain, A., Amadori, L., Argmann, C., Houten, S. M., Franzen, O., Mocci, G., Meelu, O. A., Ishikawa, K. et al.Nat Cardiovasc Res 1, 85-100 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36276926
Left-atrial long-axis shortening allows effective quantification of atrial function and optimized risk prediction following acute myocardial infarction. Backhaus, S. J., Rosel, S. F., Stiermaier, T., Schmidt-Rimpler, J., Evertz, R., Schulz, A., Lange, T., Kowallick, J. T., Kutty, S., Bigalke, B., Gutberlet, M., Hasenfuss, G., Thiele, H., Eitel, I. & Schuster, A. Eur Heart J Open 2, oeac053 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36268539
Empagliflozin Preserves Skeletal Muscle Function in a HFpEF Rat Model. Winzer, E. B., Schauer, A., Langner, E., Augstein, A., Goto, K., Mannel, A., Barthel, P., Jannasch, A., Labeit, S., Mangner, N., Linke, A. & Adams, V. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36232292
Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro. Heuschkel, M. A., Babler, A., Heyn, J., van der Vorst, E. P. C., Steenman, M., Gesper, M., Kappel, B. A., Magne, D., Goueffic, Y., Kramann, R., Jahnen-Dechent, W., Marx, N., Quillard, T. & Goettsch, C. Front Cardiovasc Med 9, 959457 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36204585
Developmental errors in the common marmoset retina. Haverkamp, S., Mietsch, M. & Briggman, K. L. Front Neuroanat 16, 1000693 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36204677
Methylation status of VTRNA2-1/nc886 is stable across populations, monozygotic twin pairs and in majority of tissues. Marttila, S., Tamminen, H., Rajic, S., Mishra, P. P., Lehtimaki, T., Raitakari, O., Kahonen, M., Kananen, L., Jylhava, J., Hagg, S., Delerue, T., Peters, A., Waldenberger, M., Kleber, M. E., Marz, W., Luoto, R., Raitanen, J., Sillanpaa, E., Laakkonen, E. K., Heikkinen, A. et al. Epigenomics 14, 1105-1124 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36200237
Serial measurements of protein and microRNA biomarkers to specify myocardial infarction subtypes. Schulte, C., Singh, B., Theofilatos, K., Sorensen, N. A., Lehmacher, J., Hartikainen, T., Haller, P. M., Westermann, D., Zeller, T., Blankenberg, S., Neumann, J. T. & Mayr, M. J Mol Cell Cardiol Plus 1, None (2022). https://www.ncbi.nlm.nih.gov/pubmed/36185590
Induced pluripotent stem cell-derived brain organoids as potential human model system for chemotherapy induced CNS toxicity. Scholz, S., Lewis, K., Saulich, F., Endres, M., Boehmerle, W. & Huehnchen, P. Front Mol Biosci 9, 1006497 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36188215
Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice. Schweizer, U., Wirth, E. K., Klopstock, T., Holter, S. M., Becker, L., Moskovitz, J., Grune, T., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Kohrle, J. & Schomburg, L. Redox Biol 57, 102490 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36182809
Integration of Hi-C with short and long-read genome sequencing reveals the structure of germline rearranged genomes. Schopflin, R., Melo, U. S., Moeinzadeh, H., Heller, D., Laupert, V., Hertzberg, J., Holtgrewe, M., Alavi, N., Klever, M. K., Jungnitsch, J., Comak, E., Turkmen, S., Horn, D., Duffourd, Y., Faivre, L., Callier, P., Sanlaville, D., Zuffardi, O., Tenconi, R., Kurtas, N. E. et al. Nat Commun 13, 6470 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36309531
Effect of Mobile Stroke Unit Dispatch in all Patients with Acute Stroke or TIA. Rohmann, J. L., Piccininni, M., Ebinger, M., Wendt, M., Weber, J. E., Schwabauer, E., Geisler, F., Freitag, E., Harmel, P., Lorenz-Meyer, I., Rohrpasser-Napierkowski, I., Nolte, C. H., Nabavi, D. G., Schmehl, I., Ekkernkamp, A., Endres, M. & Audebert, H. J. Ann Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36309933
Optimized definition of right ventricular dysfunction on computed tomography for risk stratification of pulmonary embolism. Lerchbaumer, M. H., Aviram, G., Ebner, M., Ritter, C. O., Steimke, L., Rozenbaum, Z., Adam, S. Z., Granot, Y., Hasenfuss, G., Lotz, J., Hamm, B., Konstantinides, S. V. & Lankeit, M. Eur J Radiol 157, 110554 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36308850
TAVI for patients with normal-flow low-gradient compared to high-gradient aortic stenosis. Steffen, J., Andreae, D., Nabauer, M., Reissig, N., Doldi, P. M., Haum, M., Orban, M., Theiss, H., Rizas, K., Braun, D., Peterss, S., Hausleiter, J., Massberg, S. & Deseive, S. Int J Cardiol 371, 299-304 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36306951
Detection of apoptosis by [(18)F]ML-10 after cardiac ischemia-reperfusion injury in mice. Fischer, M., Zacherl, M. J., Olivier, J., Lindner, S., Massberg, S., Bartenstein, P., Grawe, F., Ziegler, S., Brendel, M., Lehner, S., Boening, G. & Todica, A. Ann Nucl Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/36306025
Spironolactone effect on cardiac structure and function of patients with heart failure and preserved ejection fraction: a pooled analysis of three randomized trials. Ferreira, J. P., Cleland, J. G., Girerd, N., Bozec, E., Rossignol, P., Pellicori, P., Cosmi, F., Mariottoni, B., Solomon, S. D., Pitt, B., Pfeffer, M. A., Shah, A. M., Petutschnigg, J., Pieske, B., Edelmann, F. & Zannad, F. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36303266
First steps taken, but many more ahead. Beer, B. N. & Schrage, B. Eur Heart J Acute Cardiovasc Care 11, 904-905 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36306402
Catheter ablation of supraventricular tachycardias-a success story. Althoff, T. F. & Mont, L. Europace(2022). https://www.ncbi.nlm.nih.gov/pubmed/36305555
Fatty Acid Amide Hydrolase Deficiency Is Associated with Deleterious Cardiac Effects after Myocardial Ischemia and Reperfusion in Mice. Rajlic, S., Surmann, L., Zimmermann, P., Weisheit, C. K., Bindila, L., Treede, H., Velten, M., Daiber, A. & Duerr, G. D. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36293543
Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation. Ortiz-Zapater, E., Bagley, D. C., Hernandez, V. L., Roberts, L. B., Maguire, T. J. A., Voss, F., Mertins, P., Kirchner, M., Peset-Martin, I., Woszczek, G., Rosenblatt, J., Gotthardt, M., Santis, G. & Parsons, M. Nat Commun 13, 6407 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36302767
Patient-Reported Quality of Life After Intravenous Alteplase for Stroke in the WAKE-UP Trial. Jensen, M., Sehner, S., Cheng, B., Schlemm, E., Quandt, F., Barow, E., Wegscheider, K., Boutitie, F., Ebinger, M., Endres, M., Fiebach, J., Thijs, V., Lemmens, R., Muir, K., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Thomalla, G. & Gerloff, C. Neurology (2022). https://www.ncbi.nlm.nih.gov/pubmed/36302662
Image Quality Improvement Techniques and Assessment Adequacy in Clinical Optoacoustic Imaging: A Systematic Review. Dimaridis, I., Sridharan, P., Ntziachristos, V., Karlas, A. & Hadjileontiadis, L. Biosensors (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36291038
Sequences and proteins that influence mRNA processing in Trypanosoma brucei: Evolutionary conservation of SR-domain and PTB protein functions. Waithaka, A., Maiakovska, O., Grimm, D., do Nascimento, L. M. & Clayton, C. PLoS Negl Trop Dis 16, e0010876 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36288402
Targeted Temperature Management in Postresuscitation Care After Incorporating Results of the TTM2 Trial. Lusebrink, E., Binzenhofer, L., Kellnar, A., Scherer, C., Schier, J., Kleeberger, J., Stocker, T. J., Peterss, S., Hagl, C., Stark, K., Petzold, T., Fichtner, S., Braun, D., Kaab, S., Brunner, S., Theiss, H., Hausleiter, J., Massberg, S. & Orban, M. J Am Heart Assoc 11, e026539 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36285786
Standard Transfemoral Transcatheter Aortic Valve Replacement. Van Praet, K. M., Nersesian, G., Kukucka, M., Heil, E., Kofler, M., Wert, L., Falk, V., Kempfert, J., Klein, C. & Unbehaun, A. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36282201
Iron deficiency and cardiovascular disease. Savarese, G., von Haehling, S., Butler, J., Cleland, J. G., Ponikowski, P. & Anker, S. D. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36282723
Association of epicardial adipose tissue with coronary CT angiography plaque parameters on cardiovascular outcome in patients with and without diabetes mellitus. Tesche, C., Bauer, M. J., Straube, F., Rogowski, S., Baumann, S., Renker, M., Fink, N., Schoepf, U. J., Hoffmann, E. & Ebersberger, U. Atherosclerosis 363, 78-84 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36280469
Early and late renal function changes with spironolactone in patients at risk of developing heart failure: findings from the HOMAGE trial. Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Zannad, F. & Rossignol, P. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36279002
Subtype-specific plasma signatures of platelet-related protein releasate in acute pulmonary embolism. Baidildinova, G., Ten Cate, V., Nagler, M., Panova-Noeva, M., Rapp, S., Kock, T., Prochaska, J. H., Heitmeier, S., Gerdes, C., Schwers, S., Konstantinides, S. V., Munzel, T., Espinola-Klein, C., Lackner, K. J., Spronk, H. M. N., Ten Cate, H., van der Meijden, P. E. J., Leineweber, K., Wild, P. S. & Jurk, K. Thromb Res 220, 75-87 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36274391
Angiotensin 1-7 increases fiber cross-sectional area and force in juvenile mouse skeletal muscle. Albadrani, H., Ammar, T., Rajgara, R., Bader, M., Wiper-Bergeron, N. & Renaud, J. M. Am J Physiol Cell Physiol323, C1681-C1696 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36280388
Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease. Petzold, T., Zhang, Z., Ballesteros, I., Saleh, I., Polzin, A., Thienel, M., Liu, L., Ul Ain, Q., Ehreiser, V., Weber, C., Kilani, B., Mertsch, P., Gotschke, J., Cremer, S., Fu, W., Lorenz, M., Ishikawa-Ankerhold, H., Raatz, E., El-Nemr, S., Gorlach, A. et al. Immunity 55, 2285-2299 e2287 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36272416
Use of serial changes in biomarkers vs. baseline levels to predict left ventricular remodelling after STEMI. Klingenberg, R., Holtkamp, F., Grun, D., Frey, A., Jahns, V., Jahns, R., Gassenmaier, T., Hamm, C. W., Frantz, S. & Keller, T. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36271665
Fasting intervention and its clinical effects on the human host and microbiome. Forslund, S. K. J Intern Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/36271842
D-dopachrome tautomerase in cardiovascular and inflammatory diseases-A new kid on the block or just another MIF? Zan, C., Yang, B., Brandhofer, M., El Bounkari, O. & Bernhagen, J. FASEB J 36, e22601 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36269019
Role of CD40(L)-TRAF signaling in inflammation and resolution-a double-edged sword. Strohm, L., Ubbens, H., Münzel, T., Daiber, A. & Daub, S. Front Pharmacol 13, 995061 (2022).
Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals. Ripplinger, C. M., Glukhov, A. V., Kay, M. W., Boukens, B. J., Chiamvimonvat, N., Delisle, B. P., Fabritz, L., Hund, T. J., Knollmann, B. C., Li, N., Murray, K. T., Poelzing, S., Quinn, T. A., Remme, C. A., Rentschler, S. L., Rose, R. A. & Posnack, N. G. Am J Physiol Heart Circ Physiol 323, H1137-H1166 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36269644
The mega COMBO collaboration: An individual patient data pooled analysis of patients undergoing PCI with COMBO stent. Nardin, M., Pivato, C. A., Cao, D., Sartori, S., Zhang, Z., Vogel, B., Nicolas, J., Chiarito, M., Qiu, H., Chandrasekhar, J., Spirito, A., Abizaid, A., Christiansen, E. H., Colombo, A., de Winter, R. J., Haude, M., Jakobsen, L., Jensen, L. O., Krucoff, M. W., Landmesser, U. et al. Int J Cardiol 370, 149-155 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36270496
Genomic risk scores, biomolecules, and clinical conditions to predict atrial fibrillation: time to integrate what we can measure. Kaab, S., Holm, H. & Kirchhof, P. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36269625
Quadrivalvular nonbacterial thrombotic endocarditis in a patient with clear cell cervical cancer. Gabelmann, V., Grabs, F., Diestelmeier, S., Heindl, F., Vosseler, M., Münzel, T., Sagoschen, I. & Wild, J. Clin Case Rep 10, e6434 (2022).
Successful treatment of doxorubicin-induced cardiomyopathy with low-dose sacubitril/valsartan: a case report. Bell, E., Desuki, A., Karbach, S. & Göbel, S. Eur Heart J Case Rep 6, ytac396 (2022).
Comparison of Predicted and Confirmed Neo-Left Ventricular Outflow Tract After Transcatheter Mitral Valve Replacement. Puehler, T., Blanke, P., Seoudy, H., Sathananthan, J., Sellers, S. L., Meier, D., Both, M., Saad, M., Frank, D., Sondergaard, L. & Lutter, G. JACC Cardiovasc Interv 15, e219-e221 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36265952
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart. Muller, M., Eghbalian, R., Boeckel, J. N., Frese, K. S., Haas, J., Kayvanpour, E., Sedaghat-Hamedani, F., Lackner, M. K., Tugrul, O. F., Ruppert, T., Tappu, R., Martins Bordalo, D., Kneuer, J. M., Piekarek, A., Herch, S., Schudy, S., Keller, A., Grammes, N., Bischof, C., Klinke, A. et al. Nat Commun 13, 6209 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36266340
3D model-based super-resolution motion-corrected cardiac T1 mapping. Hufnagel, S., Metzner, S., Kerkering, K. M., Aigner, C. S., Kofler, A., Schulz-Menger, J., Schaeffter, T. & Kolbitsch, C. Phys Med Biol 67(2022). https://www.ncbi.nlm.nih.gov/pubmed/36265478
Diagnostic and prognostic value of the AST/ALT ratio in patients with sepsis and septic shock. Schupp, T., Weidner, K., Rusnak, J., Jawhar, S., Forner, J., Dulatahu, F., Brück, L. M., Hoffmann, U., Bertsch, T., Weiß, C., Akin, I. & Behnes, M. Scand J Gastroenterol, 1-11 (2022).
Sarcopenia and Frailty in Heart Failure: Is There a Biomarker Signature? Sato, R., Vatic, M., da Fonseca, G. W. P. & von Haehling, S. Curr Heart Fail Rep 19, 400-411 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36261756
Hospital intervention volume affects outcomes of emergency transcatheter aortic valve implantations in Germany. Oettinger, V., Heidenreich, A., Kaier, K., Zehender, M., Bode, C., Duerschmied, D., von Zur Mühlen, C., Westermann, D. & Stachon, P. Sci Rep 12, 17483 (2022).
Artificial intelligence-enabled phenotyping of patients with severe aortic stenosis: on the recovery of extra-aortic valve cardiac damage after transcatheter aortic valve replacement. Lachmann, M., Rippen, E., Schuster, T., Xhepa, E., von Scheidt, M., Trenkwalder, T., Pellegrini, C., Rheude, T., Hesse, A., Stundl, A., Harmsen, G., Yuasa, S., Schunkert, H., Kastrati, A., Laugwitz, K. L., Joner, M. & Kupatt, C. Open Heart 9 (2022).
Pulsed field ablation in patients with complex consecutive atrial tachycardia in conjunction with ultra-high density mapping: proof of concept. Gunawardene, M. A., Schaeffer, B. N., Jularic, M., Eickholt, C., Akbulak, R., Hedenus, K., Wahedi, R., Anwar, O., Gessler, N., Hartmann, J. & Willems, S. J Cardiovasc Electrophysiol (2022).
Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage. Ercu, M., Mucke, M. B., Pallien, T., Marko, L., Sholokh, A., Schachterle, C., Aydin, A., Kidd, A., Walter, S., Esmati, Y., McMurray, B. J., Lato, D. F., Yumi Sunaga-Franze, D., Dierks, P. H., Flores, B. I. M., Walker-Gray, R., Gong, M., Merticariu, C., Zuhlke, K., Russwurm, M. et al. Circulation 146, 1758-1778 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36259389
Development and External Validation of a Multivariable Prediction Model to Identify Nondiabetic Hyperglycemia and Undiagnosed Type 2 Diabetes: Diabetes Risk Assessment in Dentistry Score (DDS). Yonel, Z., Kocher, T., Chapple, I. L. C., Dietrich, T., Völzke, H., Nauck, M., Collins, G., Gray, L. J. & Holtfreter, B. J Dent Res, 220345221129807 (2022).
Riociguat and balloon pulmonary angioplasty improve prognosis in patients with inoperable chronic thromboembolic pulmonary Hypertension. Wiedenroth, C. B., Rolf, A., Steinhaus, K., Adameit, M. S. D., Kriechbaum, S. D., Haas, M., Roller, F., Hamm, C. W., Ghofrani, H. A., Mayer, E., Breithecker, A., Guth, S. & Liebetrau, C. J Heart Lung Transplant 42, 134-139 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36257870
Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy. Shahriyari, M., Islam, M. R., Sakib, S. M., Rinn, M., Rika, A., Kruger, D., Kaurani, L., Gisa, V., Winterhoff, M., Anandakumar, H., Shomroni, O., Schmidt, M., Salinas, G., Unger, A., Linke, W. A., Zschuntzsch, J., Schmidt, J., Bassel-Duby, R., Olson, E. N., Fischer, A. et al. J Cachexia Sarcopenia Muscle 13, 3106-3121 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36254806
Ticagrelor or Prasugrel in Patients With Acute Coronary Syndrome and High Bleeding Risk. Lahu, S., Presch, A., Ndrepepa, G., Menichelli, M., Valina, C., Hemetsberger, R., Witzenbichler, B., Bernlochner, I., Joner, M., Xhepa, E., Hapfelmeier, A., Kufner, S., Rifatov, N., Sager, H. B., Mayer, K., Kessler, T., Laugwitz, K. L., Richardt, G., Schunkert, H., Neumann, F. J. et al. Circ Cardiovasc Interv 15, e012204 (2022).
Deep, deep learning with BART. Blumenthal, M., Luo, G., Schilling, M., Holme, H. C. M. & Uecker, M. Magn Reson Med 89, 678-693 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36254526
Cardiac phase-resolved late gadolinium enhancement imaging. Weingärtner, S., Demirel Ö, B., Gama, F., Pierce, I., Treibel, T. A., Schulz-Menger, J. & Akçakaya, M. Front Cardiovasc Med 9, 917180 (2022).
Low ankle-brachial index and cognitive function after stroke-the PROSpective with Incident Stroke Berlin (PROSCIS-B). Stillfried, M. R. V., Sperber, P. S., Broersen, L. H. A., Huo, S., Piper, S. K., Heuschmann, P. U., Endres, M., Siegerink, B. & Liman, T. G. Front Neurol 13, 963262 (2022).
Novel insights into mouse models of ectopic proplatelet release. Spindler, M., Bergmeier, W., Stradal, T. E. B., Zhang, J., Siminovitch, K. A., Nicolai, L., Reinhold, A. & Bender, M. Blood Adv 6, 6135-6139 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36251748
ACURATE neo2 versus SAPIEN 3 Ultra for transcatheter aortic valve implantation. Pellegrini, C., Rheude, T., Renker, M., Wolf, A., Wambach, J. M., Alvarez-Covarrubias, H. A., Dörr, O., Singh, P., Charitos, E. I., Xhepa, E., Joner, M. & Kim, W. K. EuroIntervention (2022).
Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease. Nissen, S. E., Wolski, K., Cho, L., Nicholls, S. J., Kastelein, J., Leitersdorf, E., Landmesser, U., Blaha, M., Lincoff, A. M., Morishita, R., Tsimikas, S., Liu, J., Manning, B., Kozlovski, P., Lesogor, A., Thuren, T., Shibasaki, T., Matei, F., Silveira, F. S., Meunch, A. et al. Open Heart 9 (2022).
Assessing spatial learning and memory in mice: Classic radial maze versus a new animal-friendly automated radial maze allowing free access and not requiring food deprivation. Kohler, J., Mei, J., Banneke, S., Winter, Y., Endres, M. & Emmrich, J. V. Front Behav Neurosci 16, 1013624 (2022).
Patient Selection for Protected Percutaneous Coronary Intervention: Who Benefits the Most? Kim, S. H., Baumann, S., Behnes, M., Borggrefe, M. & Akin, I. Interv Cardiol Clin 11, 455-464 (2022).
A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA-DNA interactions. Warwick, T., Seredinski, S., Krause, N. M., Bains, J. K., Althaus, L., Oo, J. A., Bonetti, A., Dueck, A., Engelhardt, S., Schwalbe, H., Leisegang, M. S., Schulz, M. H. & Brandes, R. P. Brief Bioinform 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36239395
Proportion of stroke types in Madagascar: A tertiary-level hospital-based case series. Riedmann, J., Solonavalona, A. F., Rakotozafy, A. R., Ralamboson, S., Endres, M., Siegerink, B., Siebert, E., Knauss, S. & Emmrich, J. V. PLoS One 17, e0276199 (2022).
Sphingolipids in Atherosclerosis: Chimeras in Structure and Function. Peters, L., Kuebler, W. M. & Simmons, S. Int J Mol Sci 23 (2022).
Vascular and Liver Homeostasis in Juvenile Mice Require Endothelial Cyclic AMP-Dependent Protein Kinase A. Nedvetsky, P. I., Cornelissen, I., Mathivet, T., Bouleti, C., Ou, P., Baatsen, P., Zhao, X., Schuit, F., Stanchi, F., Mostov, K. E. & Gerhardt, H. Int J Mol Sci 23 (2022).
Frequency of subclavian artery stenosis in patients with mammarian artery coronary bypass and suspected coronary artery disease progression. Müller, A. M., Bertram, J., Bradaric, C., Koppara, T., Cassese, S., Xhepa, E., Heilmeier, B., Ott, I., Kastrati, A., Laugwitz, K. L., Ibrahim, T. & Dirschinger, R. J. Clin Res Cardiol (2022).
Influence of Shear Stress, Inflammation and BRD4 Inhibition on Human Endothelial Cells: A Holistic Proteomic Approach. Jarausch, J., Neuenroth, L., Andag, R., Leha, A., Fischer, A., Asif, A. R., Lenz, C. & Eidizadeh, A. Cells 11 (2022).
The Effect of Dextrose or Protein Ingestion on Circulating Growth Differentiation Factor 15 and Appetite in Older Compared to Younger Women. Herpich, C., Lehmann, S., Kochlik, B., Kleinert, M., Klaus, S., Müller-Werdan, U. & Norman, K. Nutrients 14 (2022).
[New mapping tools for catheter ablation of atrial fibrillation]. Delgado-Lopez, M., Heeger, C. H. & Tilz, R. R. Herzschrittmacherther Elektrophysiol 33, 380-385 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36239817
Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup-analysis. Chung, D. U., Burger, H., Kaiser, L., Osswald, B., Bärsch, V., Nägele, H., Knaut, M., Reichenspurner, H., Gessler, N., Willems, S., Butter, C., Pecha, S. & Hakmi, S. Heart Rhythm (2022).
Echocardiographic evaluation of left ventricular function using an automated analysis algorithm is feasible for beginners and experts: comparison with invasive and non-invasive methods. Nicol, P., Rank, A., Lenz, T., Schürmann, F., Syryca, F., Trenkwalder, T., Reinhard, W., Adolf, R., Hadamitzky, M., Kastrati, A., Joner, M., Schunkert, H. & Engel, L. C. J Echocardiogr (2022).
AntiSplodge: a neural-network-based RNA-profile deconvolution pipeline designed for spatial transcriptomics. Lund, J. B., Lindberg, E. L., Maatz, H., Pottbaecker, F., Hubner, N. & Lippert, C. NAR Genom Bioinform 4, lqac073 (2022). www.ncbi.nlm.nih.gov/pubmed/36225530
[MINOCA-myocardial infarction with nonobstructive coronary arteries]. Kowallick, J. T., Scholz, M., Schuster, A. & Lotz, J. Radiologie (Heidelb) 62, 912-919 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36227368
Autoimmune activation and hypersensitization of the AT1 and ETA receptors contributes to vascular injury in scleroderma renal crisis. Hegner, B., Kretzschmar, T., Zhu, N., Kleinau, G., Zhao, H., Kamhieh-Milz, J., Hilger, J., Schindler, R., Scheerer, P., Riemekasten, G., Philippe, A. & Catar, R. Rheumatology (Oxford) (2022). https://pubmed.ncbi.nlm.nih.gov/36227102/
A saturated map of common genetic variants associated with human height. Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S. H., Ferreira, T., Highland, H. H., Ji, Y. et al. Nature (2022). https://pubmed.ncbi.nlm.nih.gov/36224396/
Sex-specific and hormone-related differences in vascular remodelling in atherosclerosis. Yerly, A., van der Vorst, E. P. C., Baumgartner, I., Bernhard, S. M., Schindewolf, M. & Doring, Y. Eur J Clin Invest 53, e13885 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36219492
Identification and management of cancer cachexia in patients: Assessment of healthcare providers' knowledge and practice gaps. Baracos, V. E., Coats, A. J., Anker, S. D., Sherman, L., Klompenhouwer, T., International Advisory, B., Regional Advisory Boards for North America, E. & Japan. J Cachexia Sarcopenia Muscle 13, 2683-2696 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36218155
Emergency TAVI for acute heart failure due to severe aortic stenosis in critically ill patients with or without cardiogenic shock. Steffen, J., Stocker, A., Scherer, C., Haum, M., Fischer, J., Doldi, P. M., Theiss, H., Braun, D., Rizas, K., Peterß, S., Hausleiter, J., Massberg, S., Orban, M. & Deseive, S. Eur Heart J Acute Cardiovasc Care (2022).
SGLT2 Inhibitors and Peripheral Vascular Events: A Review of the Literature. Marchiori, E., Rodionov, R. N., Peters, F., Magnussen, C., Nordanstig, J., Gombert, A., Spanos, K., Jarzebska, N. & Behrendt, C. A. Heart Fail Clin 18, 609-623 (2022).
Determination of AAV properties by single amino acids: Go(o)d is in the details. Maiakovska, O., Baumgartl, C. & Grimm, D. Mol Ther Methods Clin Dev 27, 93-95 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36212908
Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease. Khera, A. V., Wang, M., Chaffin, M., Emdin, C. A., Samani, N. J., Schunkert, H., Watkins, H., McPherson, R., Erdmann, J., Elosua, R., Boerwinkle, E., Ardissino, D., Butterworth, A. S., Di Angelantonio, E., Naheed, A., Danesh, J., Chowdhury, R., Krumholz, H. M., Sheu, W. H., Rich, S. S. et al. Circ Genom Precis Med, 101161circgen121003598 (2022). https://pubmed.ncbi.nlm.nih.gov/36215124/
Progressive and Simultaneous Right and Left Atrial Remodeling Uncovered by a Comprehensive Magnetic Resonance Assessment in Atrial Fibrillation. Gunturiz-Beltrán, C., Nuñez-Garcia, M., Althoff, T. F., Borràs, R., Figueras, I. V. R. M., Garre, P., Caixal, G., Prat-González, S., Perea, R. J., Benito, E. M., Tolosana, J. M., Arbelo, E., Roca-Luque, I., Brugada, J., Sitges, M., Mont, L. & Guasch, E. J Am Heart Assoc 11, e026028 (2022).
Prevention of Oxidative Damage in Spinal Cord Ischemia Upon Aortic Surgery: First-In-Human Results of Shock Wave Therapy Prove Safety and Feasibility. Graber, M., Nägele, F., Röhrs, B. T., Hirsch, J., Pölzl, L., Moriggl, B., Mayr, A., Troger, F., Kirchmair, E., Wagner, J. F., Nowosielski, M., Mayer, L., Voelkl, J., Tancevski, I., Meyer, D., Grimm, M., Knoflach, M., Holfeld, J. & Gollmann-Tepeköylü, C. J Am Heart Assoc 11, e026076 (2022).
A novel MAP3K20 mutation causing centronuclear myopathy-6 with fiber-type disproportion in a Pakistani family. Ahmad, I., Khan, A., Noor Ul Ayan, H., Budde, B., Altmüller, J., Korejo, A. A., Nürnberg, G., Thiele, H., Tariq, M., Nürnberg, P. & Erdmann, J. J Hum Genet (2022).
Exercise MR-proANP unmasks latent right heart failure in CTEPH. Kriechbaum, S. D., Birmes, J., Wiedenroth, C. B., Adameit, M. S. D., Gruen, D., Vietheer, J., Richter, M. J., Guth, S., Roller, F. C., Rademann, M., Fischer-Rasokat, U., Rolf, A., Liebetrau, C., Hamm, C. W., Keller, T. & Rieth, A. J. J Heart Lung Transplant41, 1819-1830 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36210266
Inflammatory plasma proteins predict short-term mortality in patients with an acute myocardial infarction. Schmitz, T., Harmel, E., Heier, M., Peters, A., Linseisen, J. & Meisinger, C. J Transl Med 20, 457 (2022).
Future temperature-related mortality considering physiological and socioeconomic adaptation: a modelling framework. Rai, M., Breitner, S., Wolf, K., Peters, A., Schneider, A. & Chen, K. Lancet Planet Health 6, e784-e792 (2022).
CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research. Kotecha, D., Asselbergs, F. W., Achenbach, S., Anker, S. D., Atar, D., Baigent, C., Banerjee, A., Beger, B., Brobert, G., Casadei, B., Ceccarelli, C., Cowie, M. R., Crea, F., Cronin, M., Denaxas, S., Derix, A., Fitzsimons, D., Fredriksson, M., Gale, C. P., Gkoutos, G. V. et al. Eur Heart J 43, 3578-3588 (2022).
Kinin B1 receptor modulates mitochondrial activity responsivity in fasting and voluntary exercise. Arruda, A. C., Budu, A., de Menezes, T. N., Bader, M., Araujo, R. C. & Freitas-Lima, L. C. Life Sci 309, 121034 (2022).
Serum dihydrotestosterone is associated with adverse myocardial remodeling in patients with Aortic Valve Stenosis before and after Aortic Valve Replacement. Schafstedde, M., Nordmeyer, J., Berger, F., Knosalla, C., Mertins, P., Regitz-Zagrosek, V., Kuehne, T., Kraus, M. & Nordmeyer, S. Am J Physiol Heart Circ Physiol (2022).
Integrated control of coronary blood flow in exercising swine by adenosine, nitric oxide, and K(ATP) channels. Duncker, D. J., Sorop, O., van de Wouw, J., Fen, G., de Beer, V. J., Taverne, Y. J., de Graaff, H. J. D. & Merkus, D. Am J Physiol Heart Circ Physiol 323, H1080-H1090 (2022). www.ncbi.nlm.nih.gov/pubmed/36206049
Impact of Different Training Modalities on Molecular Alterations in Skeletal Muscle of Patients With Heart Failure With Preserved Ejection Fraction: A Substudy of the OptimEx Trial. Winzer, E. B., Augstein, A., Schauer, A., Mueller, S., Fischer-Schaepmann, T., Goto, K., Hommel, J., van Craenenbroeck, E. M., Wisløff, U., Pieske, B., Halle, M., Linke, A. & Adams, V. Circ Heart Fail 15, e009124 (2022).
Machine learning evaluation of LV outflow obstruction in hypertrophic cardiomyopathy using three-chamber cardiovascular magnetic resonance. Sahota, M., Saraskani, S. R., Xu, H., Li, L., Majeed, A. W., Hermida, U., Neubauer, S., Desai, M., Weintraub, W., Desvigne-Nickens, P., Schulz-Menger, J., Kwong, R. Y., Kramer, C. M., Young, A. A., Lamata, P. & investigators, H. Int J Cardiovasc Imaging 38, 2695-2705 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36201099
Psychosocial Characteristics of Patients Evaluated for Kidney, Liver, or Heart Transplantation. Gronewold, N., Schunn, F., Ihrig, A., Mayer, G., Wohnsland, S., Wagenlechner, P., Leuschner, M., Kreusser, M. M., Sommerer, C., Rupp, C., Friederich, H. C., Schultz, J. H. & Bruns, B. Psychosom Med 85, 98-105 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36201770
Determinants of mammography screening participation-a cross-sectional analysis of the German population-based Gutenberg Health Study (GHS). Pokora, R. M., Büttner, M., Schulz, A., Schuster, A. K., Merzenich, H., Teifke, A., Michal, M., Lackner, K., Münzel, T., Zeissig, S. R., Wild, P. S., Singer, S. & Wollschläger, D. PLoS One 17, e0275525 (2022).
The impact of cell culture media on the interaction of biopolymer-functionalized gold nanoparticles with cells: mechanical and toxicological properties. Meesaragandla, B., Komaragiri, Y., Schlüter, R., Otto, O. & Delcea, M. Sci Rep 12, 16643 (2022).
ECG performance in simultaneous recordings of five wearable devices using a new morphological noise-to-signal index and Smith-Waterman-based RR interval comparisons. Bläsing, D., Buder, A., Reiser, J. E., Nisser, M., Derlien, S. & Vollmer, M. PLoS One 17, e0274994 (2022).
Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues. Reed, E., Fellows, A., Lu, R., Rienks, M., Schmidt, L., Yin, X., Duregotti, E., Brandt, M., Krasemann, S., Hartmann, K., Barallobre-Barreiro, J., Addison, O., Cuello, F., Hansen, A. & Mayr, M. Matrix Biol Plus 16, 100122 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36193159
Prediction of activity-related energy expenditure under free-living conditions using accelerometer-derived physical activity. Jeran, S., Steinbrecher, A., Haas, V., Mähler, A., Boschmann, M., Westerterp, K. R., Brühmann, B. A., Steindorf, K. & Pischon, T. Sci Rep 12, 16578 (2022).
Data standards for transcatheter aortic valve implantation: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart). Aktaa, S., Batra, G., James, S. K., Blackman, D. J., Ludman, P. F., Mamas, M. A., Abdel-Wahab, M., Angelini, G. D., Czerny, M., Delgado, V., De Luca, G., Eustachio, A., Foldager, D., Hamm, C. W., Iung, B., Mangner, N., Mehilli, J., Murphy, G. J., Mylotte, D., Parma, R. et al. Eur Heart J Qual Care Clin Outcomes (2022).
Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis. Zernecke, A., Erhard, F., Weinberger, T., Schulz, C., Ley, K., Saliba, A. E. & Cochain, C. Cardiovasc Res (2022).
Optimisation of individual cardiovascular risk assessment in a German coronary artery disease cohort using a commercial test for genetic polymorphisms - a pilot study. Krohn, J. B., Neubauer, C., Fischer, S., Oberkanins, C., Katus, H. A. & Gleissner, C. A. Acta Cardiol, 1-11 (2022).
Depression predicts equivalized income five years later, but not vice versa: Results from the prospective Gutenberg Health Study. Wicke, F. S., Schmidt, P., Petersen, J., Ernst, M., Krakau, L., Brahler, E., Tibubos, A. N., Otten, D., Reiner, I., Michal, M., Schulz, A., Munzel, T., Wild, P. S., Konig, J., Lackner, K. J., Pfeiffer, N. & Beutel, M. E. Soc Sci Med 313, 115395 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36183523
Biomarker profiles in heart failure with preserved vs. reduced ejection fraction: results from the DIAST-CHF study. Eidizadeh, A., Schnelle, M., Leha, A., Edelmann, F., Nolte, K., Werhahn, S. M., Binder, L. & Wachter, R. ESC Heart Fail (2022).
Using pERK immunostaining to quantify neuronal activity induced by stress in zebrafish larvae. Corradi, L., Zaupa, M., Sawamiphak, S. & Filosa, A. STAR Protoc 3, 101731 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36183255
NOX4 mRNA correlates with plaque stability in patients with carotid artery stenosis. Hofmann, A., Frank, F., Wolk, S., Busch, A., Klimova, A., Sabarstinski, P., Gerlach, M., Egorov, D., Kopaliani, I., Weinert, S., Hamann, B., Poitz, D. M., Brunssen, C., Morawietz, H., Schröder, K. & Reeps, C. Redox Biol 57, 102473 (2022).
Value of PET ECG gating in a cross-validation study of cardiac function assessment by PET/MR imaging. Villagran Asiares, A., Vitadello, T., Bogdanovic, B., Solari, E. L., McIntosh, L., Schachoff, S., Ibrahim, T. & Nekolla, S. G. J Nucl Cardiol (2022).
The Angiotensin AT(2) Receptor: From a Binding Site to a Novel Therapeutic Target. Steckelings, U. M., Widdop, R. E., Sturrock, E. D., Lubbe, L., Hussain, T., Kaschina, E., Unger, T., Hallberg, A., Carey, R. M. & Sumners, C. Pharmacol Rev 74, 1051-1135 (2022).
Systematic review and meta-analysis of intravenous iron-carbohydrate complexes in HFrEF patients with iron deficiency. Sindone, A., Doehner, W. & Comin-Colet, J. ESC Heart Fail (2022).
Association of general and abdominal adiposity with postural changes in systolic blood pressure: results from the NAKO pretest and MetScan studies. Moreno Velasquez, I., Jaeschke, L., Steinbrecher, A., Boeing, H., Keil, T., Janke, J. & Pischon, T. Hypertens Res 45, 1964-1976 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36180592
Stroke genetics informs drug discovery and risk prediction across ancestries. Mishra, A., Malik, R., Hachiya, T., Jurgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., Parodi, L. et al. Nature 611, 115-123 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36180795
Cardiovascular and metabolic determinants of quality of life in patients with cancer. Evertz, R., Gödde, K., Diehl, C., Valentova, M., Garfias-Veitl, T., Braulke, F., Wulf, G. G., Overbeck, T. R., Bleckmann, A., König, A. O., Weinländer, P., Potthoff, S., Hadzibegovic, S., Lena, A., Keller, U., Landmesser, U., Schuster, A., Anker, M. S., Hasenfuß, G. & von Haehling, S. ESC Heart Fail (2022).
November
Paper of the Month
Why Angiotensin II is a Poor Choice for Circulatory Support of Ventilated COVID-19 Patients Compared to Vasopressin. Speth, R. C. & Bader, M. Med Res Arch 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36438606
REACT DX registry: Real world REACTion to atrial high rate episodes detected in implantable cardioverter-defibrillator recipients with a DX lead. O'Connor, M., Kolb, C., Klein, N., Rauwolf, T., Kuster, S., Kaab, S., Tilz, R. R., Bansch, D., Ince, H., Belke, R., Hauser, T., Rietsch, K., Kramer, J. F., Wessel, N. & Lennerz, C. Technol Health Care (2022). https://www.ncbi.nlm.nih.gov/pubmed/36442163
B lymphocyte-deficiency in mice promotes venous thrombosis. Hasselwander, S., Xia, N., Mimmler, M., Ascher, S., Knopp, T., Reifenberg, G., Karbach, S., Ruf, W., Reinhardt, C. & Li, H. Heliyon 8, e11740 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36439760
Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus (AAV) Capsid Variants. Rapti, K., Maiakovska, O., Becker, J., Szumska, J., Zayas, M., Bubeck, F., Liu, J., Gerstmann, E., Kramer, C., Wiedtke, E. & Grimm, D. J Vis Exp (2022). https://www.ncbi.nlm.nih.gov/pubmed/36342179
Treatment of advanced heart failure in adults with congenital heart disease: a narrative review and clinical cases. Sinning, C., Huntgeburth, M., Fukushima, N., Tompkins, R., Huh, J., Tataneo, S., Diller, G. P., Chen, Y. S., Zengin, E., Magnussen, C., Kaemmerer, A. S., Cho, Y. H., Blankenberg, S., Rickers, C., Harig, F., Weyand, M., Hubler, M., von Kodolitsch, Y., Oto, O., Zuckermann, A. et al. Cardiovasc Diagn Ther 12, 727-743 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36329959
Hemodynamic markers of pulmonary vasculopathy for prediction of early right heart failure and mortality after heart transplantation. Rieth, A. J., Rivinius, R., Luhring, T., Grun, D., Keller, T., Grinninger, C., Schuttler, D., Bara, C. L., Helmschrott, M., Frey, N., Sandhaus, T., Schulze, C., Kriechbaum, S., Vietheer, J., Sindermann, J., Welp, H., Lichtenberg, A., Choi, Y. H., Richter, M., Tello, K. et al. J Heart Lung Transplant(2022). https://www.ncbi.nlm.nih.gov/pubmed/36333208
SARS-CoV-2 infection causes prolonged cardiomyocyte swelling and inhibition of HIF1alpha translocation in an animal model COVID-19. Daems, M., Liesenborghs, L., Boudewijns, R., Simmonds, S. J., Kraisin, S., Van Wauwe, J., Cuijpers, I., Raman, J., Geuens, N., Buyten, T. V., Lox, M., Verhamme, P., Van Linthout, S., Martinod, K., Heymans, S., Tschope, C., Neyts, J. & Jones, E. A. V. Front Cardiovasc Med 9, 964512 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36324747
Right ventricular function in transcatheter mitral and tricuspid valve edge-to-edge repair. Stolz, L., Doldi, P. M., Weckbach, L. T., Stocker, T. J., Braun, D., Orban, M., Wild, M. G., Hagl, C., Massberg, S., Nabauer, M., Hausleiter, J. & Orban, M. Front Cardiovasc Med 9, 993618 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36312295
Verapamil inhibits Kir2.3 channels by binding to the pore and interfering with PIP(2) binding. Xynogalos, P., Rahm, A. K., Fried, S., Chasan, S., Scherer, D., Seyler, C., Katus, H. A., Frey, N. & Zitron, E. Naunyn Schmiedebergs Arch Pharmacol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36445385
Defining terms commonly used in sarcopenia research: a glossary proposed by the Global Leadership in Sarcopenia (GLIS) Steering Committee. Cawthon, P. M., Visser, M., Arai, H., Avila-Funes, J. A., Barazzoni, R., Bhasin, S., Binder, E., Bruyere, O., Cederholm, T., Chen, L. K., Cooper, C., Duque, G., Fielding, R. A., Guralnik, J., Kiel, D. P., Kirk, B., Landi, F., Sayer, A. A., Von Haehling, S., Woo, J. et al. Eur Geriatr Med 13, 1239-1244 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36445639
Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4. Ni, W., Wolf, K., Breitner, S., Zhang, S., Nikolaou, N., Ward-Caviness, C. K., Waldenberger, M., Gieger, C., Peters, A. & Schneider, A. Environ Sci Technol 56, 17815-17824 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36442845
Association between Platelet Count and Treatment Effect of Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes. Koch, T., Lahu, S., Coughlan, J. J., Cassese, S., Voll, F., Ndrepepa, G., Menichelli, M., Valina, C. M., Hemetsberger, R., Witzenbichler, B., Bernlochner, I., Joner, M., Xhepa, E., Mayer, K., Kessler, T., Laugwitz, K. L., Richardt, G., Schunkert, H., Angiolillo, D., Sibbing, D. et al. Thromb Haemost (2022). https://www.ncbi.nlm.nih.gov/pubmed/36442805
Septal myocardial scar burden predicts the response to cardiac contractility modulation in patients with heart failure. Ansari, U., Overhoff, D., Burkhoff, D., Fastner, C., Yucel, G., Roger, S., Rudic, B., Liebe, V., Borggrefe, M., Akin, I., Kuschyk, J., Papavassiliu, T. & Tulumen, E. Sci Rep 12, 20504 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36443407
Repression of the iron exporter ferroportin may contribute to hepatocyte iron overload in individuals with type 2 diabetes. Qiu, R., Alikhanyan, K., Volk, N., Marques, O., Mertens, C., Agarvas, A. R., Singh, S., Pepperkok, R., Altamura, S. & Muckenthaler, M. U. Mol Metab, 101644 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36436807
Fractal dimension of the aortic annulus: a novel predictor of paravalvular leak after transcatheter aortic valve implantation. Stachel, G., Abdel-Wahab, M., de Waha-Thiele, S., Desch, S., Feistritzer, H. J., Kitamura, M., Farhan, S., Eitel, I., Kurz, T. & Thiele, H. Int J Cardiovasc Imaging 38, 2469-2478 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36434335
Improving Survival in Cardiogenic Shock-A Propensity Score-Matched Analysis of the Impact of an Institutional Allocation Protocol to Short-Term Mechanical Circulatory Support. Ott, S., Lewin, D., Nersesian, G., Stein, J., Just, I. A., Hommel, M., Schoenrath, F., Starck, C. T., O'Brien, B., Falk, V., Potapov, E. & Lanmueller, P. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36431066
Coronary plaque characterization assessed by delayed enhancement dual-layer spectral CT angiography and optical coherence tomography. Nadjiri, J., Koppara, T., Kafka, A., Weis, F., Rasper, M., Gassert, F. G., von Schacky, C. E., Pfeiffer, D., Laugwitz, K. L., Makowski, M. R. & Ibrahim, T. Int J Cardiovasc Imaging 38, 2491-2500 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36434331
Generation of induced pluripotent stem cells from three individuals with Huntington's disease. Miller, D. C., Lisowski, P., Lickfett, S., Mlody, B., Bunning, M., Genehr, C., Ulrich, C., Wanker, E. E., Diecke, S., Priller, J. & Prigione, A. Stem Cell Res 65, 102976 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36434993
TREML2 Gene Expression and Its Missense Variant rs3747742 Associate with White Matter Hyperintensity Volume and Alzheimer's Disease-Related Brain Atrophy in the General Population. Kuhn, A. L., Frenzel, S., Teumer, A., Wittfeld, K., Garvert, L., Weihs, A., Homuth, G., Prokisch, H., Bulow, R., Nauck, M., Volker, U., Volzke, H., Grabe, H. J. & Van der Auwera, S. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36430248
Association between Alcohol Consumption and Health-Related Quality of Life among Hospital and Ambulatory Care Patients with Past Year Depressive Symptoms. Krause, K., Guertler, D., Moehring, A., Batra, A., Eck, S., Rumpf, H. J., Bischof, G., Buchholz, M., John, U. & Meyer, C. Int J Environ Res Public Health19 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36429382
Transgenic rat with overproduction of ubiquitous angiotensin-(1-7) presents neuroprotection in a model of ischemia and reperfusion. Kangussu, L. M., Almeida-Santos, A. F., Fernandes, L. F., Alenina, N., Bader, M., Santos, R. A. S., Massensini, A. R. & Campagnole-Santos, M. J. Brain Res Bull 192, 184-191 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36435363
Evolving Role of Catheter Ablation for Atrial Fibrillation: Early and Effective Rhythm Control. Chen, S., Yin, Y., Ling, Z., Meyer, C., Purerfellner, H., Martinek, M., Kiuchi, M. G., Futyma, P., Zhu, L., Schratter, A., Wang, J., Acou, W. J., Sommer, P., Ouyang, F., Liu, S., Chun, J. K. R. & Schmidt, B. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36431348
The Effect of a Prasugrel- versus a Ticagrelor-based Strategy on Total Ischemic and Bleeding Events in Patients with Acute Coronary Syndromes. Aytekin, A., Coughlan, J. J., Ndrepepa, G., Cassese, S., Lahu, S., Kufner, S., Mayer, K., Xhepa, E., Gewalt, S., Joner, M., Hapfelmeier, A., Angiolillo, D. J., Menichelli, M., Richardt, G., Neumann, F. J., Schunkert, H. & Kastrati, A. Eur Heart J Cardiovasc Pharmacother (2022). https://www.ncbi.nlm.nih.gov/pubmed/36434779
Genetic and phenotypic spectrum in the NONO-associated syndromic disorder. Roessler, F., Beck, A. E., Susie, B., Tobias, B., Begtrup, A., Biskup, S., Caluseriu, O., Delanty, N., Frohlich, C., Greally, M. T., Karnstedt, M., Klockner, C., Kurtzberg, J., Schubert, S., Schulze, M., Weidenbach, M., Westphal, D. S., White, M., Wolf, C. M., Zyskind, J. et al. Am J Med Genet A (2022). https://www.ncbi.nlm.nih.gov/pubmed/36426740
Dataset of a retrospective multicenter cohort study on characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis. Muller-Jensen, L., Zierold, S., Versluis, J. M., Boehmerle, W., Huehnchen, P., Endres, M., Mohr, R., Compter, A., Blank, C. U., Hagenacker, T., Meier, F., Reinhardt, L., Gesierich, A., Salzmann, M., Hassel, J. C., Ugurel, S., Zimmer, L., Banks, P., Spain, L., Soon, J. A. et al. Data Brief 45, 108649 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36426082
Editorial: Extracellular vesicles in cardiovascular inflammation and calcification. Krohn, J. B., Aikawa, E., Aikawa, M., Hutcheson, J. D., Sahoo, S. & Fish, J. E. Front Cardiovasc Med 9, 1077124 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36426218
Parental mutations influence wild-type offspring via transcriptional adaptation. Jiang, Z., El-Brolosy, M. A., Serobyan, V., Welker, J. M., Retzer, N., Dooley, C. M., Jakutis, G., Juan, T., Fukuda, N., Maischein, H. M., Balciunas, D. & Stainier, D. Y. R. Sci Adv 8, eabj2029 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36427314
Case Fatality of Hospitalized Patients with COVID-19 Infection Suffering from Acute Respiratory Distress Syndrome in Germany. Sagoschen, I., Keller, K., Wild, J., Munzel, T. & Hobohm, L. Viruses 14(2022). https://www.ncbi.nlm.nih.gov/pubmed/36423124
Integrating Mechanisms in Thrombotic Peripheral Arterial Disease. Nagy, M., van der Meijden, P. E. J., Glunz, J., Schurgers, L., Lutgens, E., Ten Cate, H., Heitmeier, S. & Spronk, H. M. H. Pharmaceuticals (Basel) 15(2022). https://www.ncbi.nlm.nih.gov/pubmed/36422558
A New Laboratory Workflow Integrating the Free Light Chains Kappa Quotient into Routine CSF Analysis. Hannich, M. J., Abdullah, M. R., Budde, K., Petersmann, A., Nauck, M., Dressel, A. & Susse, M. Biomolecules 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36421703
Atrial Fibrillation and Transvenous Lead Extraction-A Comprehensive Subgroup Analysis of the GermAn Laser Lead Extraction RegistrY (GALLERY). Chung, D. U., Pecha, S., Burger, H., Anwar, O., Eickholt, C., Nagele, H., Reichenspurner, H., Gessler, N., Willems, S., Butter, C., Hakmi, S. & Investigators, G. Medicina (Kaunas) 58 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36422224
Hemodynamic force assessment by cardiovascular magnetic resonance in HFpEF: A case-control substudy from the HFpEF stress trial. Backhaus, S. J., Uzun, H., Rosel, S. F., Schulz, A., Lange, T., Crawley, R. J., Evertz, R., Hasenfuss, G. & Schuster, A. EBioMedicine 86, 104334 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36423376
Myocardial extracellular volume is a non-invasive tissue marker of heart failure in patients with transposition of the great arteries and systemic right ventricle. Al-Wakeel-Marquard, N., Ferreira da Silva, T., Berger, F., Kuehne, T. & Messroghli, D. R. Frontiers in Pediatrics 10, 949078 (2022).
Changes in miRNA expression in patients with peripheral arterial vascular disease during moderate- and vigorous-intensity physical activity. Sieland, J., Niederer, D., Engeroff, T., Vogt, L., Troidl, C., Schmitz-Rixen, T., Banzer, W. & Troidl, K. Eur J Appl Physiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36418750
Fin ray branching is defined by TRAP(+) osteolytic tubules in zebrafish. Cardeira-da-Silva, J., Bensimon-Brito, A., Tarasco, M., Brandao, A. S., Rosa, J. T., Borbinha, J., Almeida, P. J., Jacinto, A., Cancela, M. L., Gavaia, P. J., Stainier, D. Y. R. & Laize, V. Proc Natl Acad Sci U S A 119, e2209231119 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36417434
E-cigarette exposure augments murine abdominal aortic aneurysm development: role of Chil1. Mulorz, J., Spin, J. M., Mulorz, P., Wagenhauser, M., Deng, A., Mattern, K., Rhee, Y. H., Toyama, K., Adam, M., Schelzig, H., Maegdefessel, L. & Tsao, P. S. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/36413508
Impact of cryoballoon application abortion due to phrenic nerve injury on reconnection rates: a YETI subgroup analysis. Heeger, C. H., Popescu, S. S., Sohns, C., Pott, A., Metzner, A., Inaba, O., Straube, F., Kuniss, M., Aryana, A., Miyazaki, S., Cay, S., Ehrlich, J. R., El-Battrawy, I., Martinek, M., Saguner, A. M., Tscholl, V., Yalin, K., Lyan, E., Su, W., Papiashvili, G. et al. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/36414239
3 Tesla magnetic resonance imaging in patients with cardiac implantable electronic devices: a single centre experience. Fluschnik, N., Tahir, E., Erley, J., Mullerleile, K., Metzner, A., Wenzel, J. P., Guerreiro, H., Adam, G., Blankenberg, S., Kirchhof, P., Tonnis, T. & Nikorowitsch, J. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/36413601
Free-breathing myocardial T(1) mapping using inversion-recovery radial FLASH and motion-resolved model-based reconstruction. Wang, X., Rosenzweig, S., Roeloffs, V., Blumenthal, M., Scholand, N., Tan, Z., Holme, H. C. M., Unterberg-Buchwald, C., Hinkel, R. & Uecker, M. Magn Reson Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/36404631
Impact of time between thrombolysis and endovascular thrombectomy on outcomes in patients with acute ischaemic stroke. Wagner, L., Mohrbach, D., Ebinger, M., Endres, M., Nolte, C. H., Harmel, P., Audebert, H. J., Rohmann, J. L. & Siegerink, B. Front Neurol 13, 1018630 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36408513
Early myocardial oedema can predict subsequent cardiomyopathy in high-dose anthracycline therapy. Muehlberg, F., Kornfeld, M., Zange, L., Ghani, S., Reichardt, A., Reichardt, P. & Schulz-Menger, J. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36404640
Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study. Yao, Y., Schneider, A., Wolf, K., Zhang, S., Wang-Sattler, R., Peters, A. & Breitner, S. Environ Int 170, 107632 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36402035
A managed care system with telemedicine support for neurological emergencies. Erdur, H., Weber, J. E., Angermaier, A., Kinze, S., Sotoodeh, A., Gorski, C., Bollweg, K., Ernst, S., Kandil, F. I., Behrens, J., Ganeshan, R., Keysers, A., Kotlarz-Bottcher, M., Peters, D., Schlemm, L., Stangenberg-Gliss, K., Witt, C., Hennig, B., Reber, K. C., Schneider, U. et al. Ann Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36401341
Comparative single-cell analysis of the adult heart and coronary vasculature. Balachandran, S., Pozojevic, J., Sreenivasan, V. K. A. & Spielmann, M. Mamm Genome (2022). https://www.ncbi.nlm.nih.gov/pubmed/36401619
Analysis of the adiponectin paradox in healthy older people. Walowski, C. O., Herpich, C., Enderle, J., Braun, W., Both, M., Hasler, M., Muller, M. J., Norman, K. & Bosy-Westphal, A. J Cachexia Sarcopenia Muscle(2022). https://www.ncbi.nlm.nih.gov/pubmed/36401062
How slimming regulatory T cells limit atherosclerosis: Mechanistic insights into T cell lipid metabolism. van der Vorst, E. P. C. & Doring, Y. Atherosclerosis 362, 23-25 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36400604
A specific new biomarker for atrial fibrillation and its sequelae? Sinner, M. F. & von Falkenhausen, A. S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36399389
Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide). Zeidler, J. D., Chini, C. C. S., Kanamori, K. S., Kashyap, S., Espindola-Netto, J. M., Thompson, K., Warner, G., Cabral, F. S., Peclat, T. R., Gomez, L. S., Lopez, S. A., Wandersee, M. K., Schoon, R. A., Reid, K., Menzies, K., Beckedorff, F., Reid, J. M., Brachs, S., Meyer, R. G., Meyer-Ficca, M. L. et al. iScience 25, 105431 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36388973
Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial. Voci, D., Gotschi, A., Held, U., Bingisser, R., Colucci, G., Duerschmied, D., Fumagalli, R. M., Gerber, B., Hasse, B., Keller, D. I., Konstantinides, S. V., Mach, F., Rampini, S. K., Righini, M., Robert-Ebadi, H., Rosemann, T., Roth-Zetzsche, S., Sebastian, T., Simon, N. R., Spirk, D. et al. Thromb Res 221, 157-163 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36396519
Preliminary results of the cross-sectional associations of sedentary behavior and physical activity with serum brain-derived neurotrophic factor in adults with coronary heart disease. Ullrich, A., Wenzel, K., Bahls, M., Voigt, L., Konemann, S., Dorr, M., Wurm, S. & Ulbricht, S. Sci Rep 12, 19685 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36385629
Assessment of health-related quality of life in individuals with depressive symptoms: validity and responsiveness of the EQ-5D-3L and the SF-6D. Stolz, M., Albus, C., Beutel, M. E., Deter, H. C., Fritzsche, K., Herrmann-Lingen, C., Michal, M., Petrowski, K., Ronel, J., Schultz, J. H., Sollner, W., Weber, C., de Zwaan, M. & Krauth, C. Eur J Health Econ (2022). https://www.ncbi.nlm.nih.gov/pubmed/36385438
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Oo, J. A., Palfi, K., Warwick, T., Wittig, I., Prieto-Garcia, C., Matkovic, V., Tomaskovic, I., Boos, F., Izquierdo Ponce, J., Teichmann, T., Petriukov, K., Haydar, S., Maegdefessel, L., Wu, Z., Pham, M. D., Krishnan, J., Baker, A. H., Gunther, S., Ulrich, H. D., Dikic, I. et al. Cell Rep 41, 111670 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36384122
Discovery of novel eGFR-associated multiple independent signals using a quasi-adaptive method. Ghasemi, S., Becker, T., Grabe, H. J. & Teumer, A. Front Genet 13, 997302 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36386835
Regularization approaches in clinical biostatistics: A review of methods and their applications. Friedrich, S., Groll, A., Ickstadt, K., Kneib, T., Pauly, M., Rahnenfuhrer, J. & Friede, T. Stat Methods Med Res, 9622802221133557 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36384320
Incidence, recurrence and management of electrical storm in Brugada syndrome. El-Battrawy, I., Roterberg, G., Kowitz, J., Aweimer, A., Lang, S., Mugge, A., Zhou, X. & Akin, I. Front Cardiovasc Med 9, 981715 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36386327
Development and validation of a prognostic model for the early identification of COVID-19 patients at risk of developing common long COVID symptoms. Deforth, M., Gebhard, C. E., Bengs, S., Buehler, P. K., Schuepbach, R. A., Zinkernagel, A. S., Brugger, S. D., Acevedo, C. T., Patriki, D., Wiggli, B., Twerenbold, R., Kuster, G. M., Pargger, H., Schefold, J. C., Spinetti, T., Wendel-Garcia, P. D., Hofmaenner, D. A., Gysi, B., Siegemund, M., Heinze, G. et al. Diagn Progn Res 6, 22 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36384641
The relationship between Alzheimer's-related brain atrophy patterns and sleep macro-architecture. Weihs, A., Frenzel, S., Garvert, L., Kuhn, L., Wittfeld, K., Ewert, R., Fietze, I., Penzel, T., Stubbe, B., Szentkiralyi, A., Wulms, N., Volzke, H. & Grabe, H. J. Alzheimers Dement (Amst) 14, e12371 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36381559
Lower levels of vWF are associated with lower risk of cardiovascular disease. van Paridon, P. C. S., Panova-Noeva, M., van Oerle, R., Schulz, A., Prochaska, J. H., Arnold, N., Schmidtmann, I., Beutel, M., Pfeiffer, N., Munzel, T., Lackner, K. J., Ten Cate, H., Wild, P. S. & Spronk, H. M. H. Res Pract Thromb Haemost6, e12797 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36381288
Frailty is characterized by biomarker patterns reflecting inflammation or muscle catabolism in multi-morbid patients. Kochlik, B., Franz, K., Henning, T., Weber, D., Wernitz, A., Herpich, C., Jannasch, F., Aykac, V., Muller-Werdan, U., Schulze, M. B., Grune, T. & Norman, K. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/36377255
Letter to the editor "Cardiac function in critically ill patients with severe COVID: A prospective cross-sectional study in mechanically ventilated patients". Dandel, M. J Crit Care 73, 154217 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36379138
Replication collisions induced by de-repressed S-phase transcription are connected with malignant transformation of adult stem cells. Zhang, T., Kunne, C., Ding, D., Gunther, S., Guo, X., Zhou, Y., Yuan, X. & Braun, T. Nat Commun 13, 6907 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36376321
Atrial Fibrillation Risk Assessment after Embolic Stroke of Undetermined Source. von Falkenhausen, A. S., Feil, K., Sinner, M. F., Schonecker, S., Muller, J., Wischmann, J., Eiffener, E., Clauss, S., Poli, S., Poli, K., Zuern, C. S., Ziemann, U., Berrouschot, J., Kitsiou, A., Schabitz, W. R., Dieterich, M., Massberg, S., Kaab, S. & Kellert, L. Ann Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36373166
Pharmacologic treatment of delirium symptoms: A systematic review. Sadlonova, M., Duque, L., Smith, D., Madva, E. N., Amonoo, H. L., Vogelsang, J., Staton, S. C., von Arnim, C. A. F., Huffman, J. C. & Celano, C. M. Gen Hosp Psychiatry 79, 60-75 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36375344
Cardiac fibroblasts and mechanosensation in heart development, health and disease. Pesce, M., Duda, G. N., Forte, G., Girao, H., Raya, A., Roca-Cusachs, P., Sluijter, J. P. G., Tschope, C. & Van Linthout, S. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36376437
Higher short-term mortality of Evolut versus Sapien 3: A piece of the puzzle? Kim, W. K. & Abdel-Wahab, M. Int J Cardiol 370, 351-352 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36375596
Atrial fibrillation screening perspectives after STROKESTOP and LOOP. Freedman, B. & Schnabel, R. B. Nat Rev Cardiol 20, 1-2 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36376431
Prediction of liver-related mortality in a community setting. Schneider, C. V., Gross, S. & Strnad, P. J Hepatol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36370952
Prognostic value of De Ritis ratio with aspartate aminotransferase and alanine aminotransferase within the reference range. Ndrepepa, G., Holdenrieder, S. & Kastrati, A. Clinica Chimica Acta 538, 46-52 (2023).
Complete Left-Atrial Lesion Set versus Pulmonary Vein Isolation Only in Patients with Paroxysmal AF Undergoing CABG or AVR. Yildirim, Y., Petersen, J., Aydin, A., Alassar, Y., Reichenspurner, H. & Pecha, S. Medicina (Kaunas) 58 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36363563
Small Molecule BRD4 Inhibitors Apabetalone and JQ1 Rescues Endothelial Cells Dysfunction, Protects Monolayer Integrity and Reduces Midkine Expression. Shahid, S., Pantakani, M., Binder, L., Fischer, A., Pantakani, K. & Asif, A. R. Molecules 27 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36364277
Prevalence and Treatment Outcomes of Arrhythmias in Patients with Single Ventricle Physiology over the Age of 40 Years. Pujol, C., Hessling, G., Telishevska, M., Schiele, S., Deisenhofer, I., Ewert, P. & Tutarel, O. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36362800
Deep phenotyping of two preclinical mouse models and a cohort of RBM20 mutation carriers reveals no sex-dependent disease severity in RBM20 cardiomyopathy. Lennermann, D. C., Pepin, M. E., Grosch, M., Konrad, L., Kemmling, E., Hartmann, J., Nolte, J. L., Clauder-Munster, S., Kayvanpour, E., Sedaghat-Hamedani, F., Haas, J., Meder, B., van den Boogaard, M., Amin, A. S., Dewenter, M., Kruger, M., Steinmetz, L. M., Backs, J. & van den Hoogenhof, M. M. G. Am J Physiol Heart Circ Physiol 323, H1296-H1310 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36367695
Temporal Trends in Patients with Peripheral Artery Disease Influenced by COVID-19 Pandemic. Keller, K., Schmitt, V. H., Hobohm, L. M. A., Brochhausen, C., Munzel, T. & Espinola-Klein, C. J Clin Med 11(2022). https://www.ncbi.nlm.nih.gov/pubmed/36362660
Evaluation of Pharmacological Rescue of Melanocortin-4 Receptor Nonsense Mutations by Aminoglycoside. Hopfner, F., Paisdzior, S., Reininghaus, N., Sohail, I., Scheerer, P., Annibale, P., Biebermann, H. & Kuhnen, P. Life (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36362948
Acute Exposure to Simulated Nocturnal Train Noise Leads to Impaired Sleep Quality and Endothelial Dysfunction in Young Healthy Men and Women: A Sex-Specific Analysis. Hahad, O., Herzog, J., Roosli, M., Schmidt, F. P., Daiber, A. & Munzel, T. Int J Environ Res Public Health 19 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36360723
Negative Impact of the UEFA European Soccer Championship on Central Hemodynamics and Arterial Stiffness: A Multicenter Study. Franzen, K. F., Mortensen, K., Ott, C., Herber, K., Busse, M., Soling, C., Schneppe, D., Lassig, S., Dorr, M., Tilz, R., Dromann, D., Schunkert, H. & Reppel, M. Life (Basel) 12(2022). https://www.ncbi.nlm.nih.gov/pubmed/36362851
Cardiac Troponin I Reveals Diagnostic and Prognostic Superiority to Aminoterminal Pro-B-Type Natriuretic Peptide in Sepsis and Septic Shock. Forner, J., Schupp, T., Weidner, K., Rusnak, J., Jawhar, S., Dulatahu, F., Bruck, L. M., Behnes, M., Hoffmann, U., Bertsch, T., Kittel, M. & Akin, I. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36362826
Effect of sulfasalazine on endothelium-dependent vascular response by the activation of Nrf2 signalling pathway. Sonmez, M. I., Shahzadi, A., Kose, C., Sonmez, H., Ozyazgan, S. & Akkan, A. G. Front Pharmacol 13, 979300 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36353481
GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation. Guillamat-Prats, R., Hering, D., Derle, A., Rami, M., Hardtner, C., Santovito, D., Rinne, P., Bindila, L., Hristov, M., Pagano, S., Vuilleumier, N., Schmid, S., Janjic, A., Enard, W., Weber, C., Maegdefessel, L., Faussner, A., Hilgendorf, I. & Steffens, S. Nature Cardiovascular Research (2022).
The impact of the PCSK-9/VLDL-Receptor axis on inflammatory cell polarization. Barcena, M. L., Estepa, M., Marx, L., Breiter, A., Haritonow, N. & Stawowy, P. Cytokine 161, 156077 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36356495
Sex differences in imaging and clinical characteristics of patients from the WAKE-UP trial. Wouters, A., Scheldeman, L., Liessens, H., Dupont, P., Boutitie, F., Cheng, B., Ebinger, M., Endres, M., Fiebach, J. B., Gerloff, C., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Thijs, V., Thomalla, G. & Lemmens, R. Eur J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36349887
Pan-claudin family interactome analysis reveals shared and specific interactions. Suarez-Artiles, L., Breiderhoff, T., Girardello, R., Gonschior, H., Rodius, S., Lesur, A., Reimer, U., Ramberger, E., Perez-Hernandez, D., Muller, D., Mertins, P. & Dittmar, G. Cell Rep 41, 111588 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36351382
Properdin (factor P) as a new target cleaved by factor XIa: Intrinsic coagulation at the crossroads with inflammation. Luo, Q. & Wenzel, P. Res Pract Thromb Haemost 6, e12835 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36349265
Inducible over-expression of cardiac Nos1ap causes short QT syndrome in transgenic mice. Jansch, M., Lubomirov, L. T., Trum, M., Williams, T., Schmitt, J., Schuh, K., Qadri, F., Maier, L. S., Bader, M. & Ritter, O. FEBS Open Bio (2022). https://www.ncbi.nlm.nih.gov/pubmed/36352324
The atypical beta-blocker S-oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model. Yuan, L., Springer, J., Palus, S., Busquets, S., Jove, Q., Alves de Lima Junior, E., Anker, M. S., von Haehling, S., Alvarez Ladron, N., Millman, O., Oosterlee, A., Szymczyk, A., Lopez-Soriano, F. J., Anker, S. D., Coats, A. J. S. & Argiles, J. M. J Cachexia Sarcopenia Muscle (2022). https://www.ncbi.nlm.nih.gov/pubmed/36346141
Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype. Wesseler, F., Lohmann, S., Riege, D., Halver, J., Roth, A., Pichlo, C., Weber, S., Takamiya, M., Muller, E., Ketzel, J., Flegel, J., Gihring, A., Rastegar, S., Bertrand, J., Baumann, U., Knippschild, U., Peifer, C., Sievers, S., Waldmann, H. & Schade, D. J Med Chem 65, 15263-15281 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36346705
Magnetique: an interactive web application to explore transcriptome signatures of heart failure. Britto-Borges, T., Ludt, A., Boileau, E., Gjerga, E., Marini, F. & Dieterich, C. J Transl Med 20, 513 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36345035
Mid-term performance of decellularized equine pericardium in congenital heart surgery. Weixler, V. H. M., Kuschnerus, K., Romanchenko, O., Ovroutski, S., Cho, M. Y., Berger, F., Sigler, M., Sinzobahamvya, N., Photiadis, J. & Murin, P. Interact Cardiovasc Thorac Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/36342192
Morphological characteristics of lesions with thin cap fibroatheroma-a substudy from the COMBINE (OCT-FFR) trial. Roleder-Dylewska, M., Gasior, P., Hommels, T. M., Roleder, T., Berta, B., Ang, H. Y., Ng, J. C. K., Hermanides, R. S., Fabris, E., AJJ, I. J., Kauer, F., Alfonso, F., von Birgelen, C., Escaned, J., Camaro, C., Kennedy, M. W., Pereira, B., Magro, M., Nef, H., Reith, S. et al. Eur Heart J Cardiovasc Imaging(2022). https://www.ncbi.nlm.nih.gov/pubmed/36342269
Brain network architecture constrains age-related cortical thinning. Petersen, M., Nagele, F. L., Mayer, C., Schell, M., Rimmele, D. L., Petersen, E., Kuhn, S., Gallinat, J., Hanning, U., Fiehler, J., Twerenbold, R., Gerloff, C., Thomalla, G. & Cheng, B. Neuroimage 264, 119721 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36341953
Rapid estimation of 2D relative B1+ -maps from localizers in the human heart at 7T using deep learning. Krueger, F., Aigner, C. S., Hammernik, K., Dietrich, S., Lutz, M., Schulz-Menger, J., Schaeffter, T. & Schmitter, S. Magn Reson Med 89, 1002-1015 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36336877
Network reconstruction for trans acting genetic loci using multi-omics data and prior information. Hawe, J. S., Saha, A., Waldenberger, M., Kunze, S., Wahl, S., Muller-Nurasyid, M., Prokisch, H., Grallert, H., Herder, C., Peters, A., Strauch, K., Theis, F. J., Gieger, C., Chambers, J., Battle, A. & Heinig, M. Genome Med14, 125 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36344995
Unravelling the impact of aging on the human endothelial lncRNA transcriptome. Drekolia, M. K., Talyan, S., Cordellini Emidio, R., Boon, R. A., Guenther, S., Looso, M., Dumbovic, G. & Bibli, S. I. Front Genet13, 1035380 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36338971
A Randomized Controlled Trial Comparing Apixaban to the Vitamin K-antagonist Phenprocoumon in Patients on Chronic Hemodialysis: The AXADIA-AFNET 8 study. Reinecke, H., Engelbertz, C., Bauersachs, R., Breithardt, G., Echterhoff, H. H., Gerbeta, J., Haeusler, K. G., Hewing, B., Hoyer, J., Juergensmeyer, S., Klingenheben, T., Knapp, G., Rump, L. C., Schmidt-Guertler, H., Wanner, C., Kirchhof, P. & Goerlich, D. Circulation (2022). https://www.ncbi.nlm.nih.gov/pubmed/36335915
Diagnostic and Therapeutic Decision-Making Problems Evoked by Mitral Regurgitation in Heart Failure With Preserved Left Ventricular Ejection Fraction. Dandel, M. Am J Cardiol 186, 244 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36336521
Lamin A/C-dependent chromatin architecture safeguards naive pluripotency to prevent aberrant cardiovascular cell fate and function. Wang, Y., Elsherbiny, A., Kessler, L., Cordero, J., Shi, H., Serke, H., Lityagina, O., Trogisch, F. A., Mohammadi, M. M., El-Battrawy, I., Backs, J., Wieland, T., Heineke, J. & Dobreva, G. Nat Commun 13, 6663 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36333314
Population-Level Implications of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Preserved Ejection Fraction in the US. Talha, K. M., Butler, J., Greene, S. J., Aggarwal, R., Anker, S. D., Claggett, B. L., Solomon, S. D., McMurray, J. J. V., Vaduganathan, M. & Fonarow, G. C. JAMA Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36334258
Inclisiran and cardiovascular events: a patient-level analysis of phase III trials. Ray, K. K., Raal, F. J., Kallend, D. G., Jaros, M. J., Koenig, W., Leiter, L. A., Landmesser, U., Schwartz, G. G., Lawrence, D., Friedman, A., Garcia Conde, L., Wright, R. S. & investigators, O. P. I. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36331326
Effect of inclisiran on lipids in primary prevention: the ORION-11 trial. Ray, K. K., Kallend, D., Leiter, L. A., Raal, F. J., Koenig, W., Jaros, M. J., Schwartz, G. G., Landmesser, U., Garcia Conde, L., Wright, R. S. & Investigators, O.-. Eur Heart J 43, 5047-5057 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36331315
Minimal Clinically Important Difference for Six-minute Walk Test in Patients with HFrEF and Iron Deficiency. Khan, M. S., Anker, S. D., Friede, T., Jankowska, E. A., Metra, M., Pina, I. L., Coats, A. J., Rosano, G., Roubert, B., Goehring, U. M., Dorigotti, F., Comin-Colet, J., Van Veldhuisen, D. J., Filippatos, G. S., Ponikowski, P. & Butler, J. J Card Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36332897
Low-density lipoprotein cholesterol goal attainment in patients with clinical evidence of familial hypercholesterolemia and elevated Lp(a). Schwarz, A., Demuth, I., Landmesser, U., Haghikia, A., Konig, M. & Steinhagen-Thiessen, E. Lipids Health Dis 21, 114 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36324160
HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Leisegang, M. S., Bains, J. K., Seredinski, S., Oo, J. A., Krause, N. M., Kuo, C. C., Gunther, S., Senturk Cetin, N., Warwick, T., Cao, C., Boos, F., Izquierdo Ponce, J., Haydar, S., Bednarz, R., Valasarajan, C., Fuhrmann, D. C., Preussner, J., Looso, M., Pullamsetti, S. S., Schulz, M. H. et al. Nat Commun 13, 6563 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36323673
Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients. Bauer, A., Pachl, E., Hellmuth, J. C., Kneidinger, N., Heydarian, M., Frankenberger, M., Stubbe, H. C., Ryffel, B., Petrera, A., Hauck, S. M., Behr, J., Kaiser, R., Scherer, C., Deng, L., Teupser, D., Ahmidi, N., Muenchhoff, M., Schubert, B. & Hilgendorff, A. Biochim Biophys Acta Mol Basis Dis 1869, 166592 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36328146
Weight change and clinical outcomes in heart failure with reduced ejection fraction: insights from EMPEROR-Reduced. Anker, S. D., Khan, M. S., Butler, J., Ofstad, A. P., Peil, B., Pfarr, E., Doehner, W., Sattar, N., Coats, A. J. S., Filippatos, G., Ferreira, J. P., Zannad, F., Pocock, S. & Packer, M. Eur J Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36325584
Hormonal therapies up-regulate MANF and overcome female susceptibility to immune checkpoint inhibitor myocarditis. Zhang, Y., Sun, C., Li, Y., Qin, J., Amancherla, K., Jing, Y., Hu, Q., Liang, K., Zhang, Z., Ye, Y., Huang, L. A., Nguyen, T. K., Egranov, S. D., Zhao, Z., Wu, A., Xi, Y., Yao, J., Hung, M. C., Calin, G. A., Cheng, J. et al. Sci Transl Med 14, eabo1981 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36322628
Association of spermidine plasma levels with brain aging in a population-based study. Wortha, S. M., Frenzel, S., Bahls, M., Habes, M., Wittfeld, K., Van der Auwera, S., Bulow, R., Zylla, S., Friedrich, N., Nauck, M., Volzke, H., Grabe, H. J., Schwarz, C. & Floel, A. Alzheimers Dement (2022). https://www.ncbi.nlm.nih.gov/pubmed/36321615
Left atrial strain correlates with severity of cardiac involvement in Anderson-Fabry disease. Halfmann, M. C., Altmann, S., Schoepf, U. J., Reichardt, C., Hennermann, J. B., Kreitner, K. F., Kloeckner, R., Hahn, F., Dueber, C., Varga-Szemes, A., Kampmann, C. & Emrich, T. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36322192
[Treat calcified stenoses correctly]. Blessing, R. & Gori, T. Herz 47, 503-512 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36322196
[Cardiac pacing – new devices, new techniques]. Reincke, S., Delgado, M., Vogler, J. & Tilz, R. R. Dtsch Med Wochenschr 147, 1469-1476 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36318910
Protective behavior and SARS-CoV-2 infection risk in the population - Results from the Gutenberg COVID-19 study. Baumkotter, R., Yilmaz, S., Zahn, D., Fenzl, K., Prochaska, J. H., Rossmann, H., Schmidtmann, I., Schuster, A. K., Beutel, M. E., Lackner, K. J., Munzel, T. & Wild, P. S. BMC Public Health 22, 1993 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36316662
Single-Center Experience With a Self-Expandable Venous Cannula During Minimally Invasive Cardiac Surgery. Van Praet, K. M., Kofler, M., Meyer, A., Sundermann, S. H., Hommel, M., Falk, V. & Kempfert, J. Innovations (Phila), 15569845221131534 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36314445
Neutrophils in aging and aging-related pathologies. Van Avondt, K., Strecker, J. K., Tulotta, C., Minnerup, J., Schulz, C. & Soehnlein, O. Immunol Rev (2022). https://www.ncbi.nlm.nih.gov/pubmed/36315403
Intermittent Chest Pain in a 46-Year-Old Patient. Plappert, C., Sherif, M. & Oeing, C. JAMA 328, 2058-2059 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36315193
Mechanical recovery plug for left ventricular assist device explantation. Loforte, A., Gliozzi, G., Nersesian, G., Votano, D., Potapov, E. & Pacini, D. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36315037
Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses. Gaziano, L., Sun, L., Arnold, M., Bell, S., Cho, K., Kaptoge, S. K., Song, R. J., Burgess, S., Posner, D. C., Mosconi, K., Robinson-Cohen, C., Mason, A. M., Bolton, T. R., Tao, R., Allara, E., Schubert, P., Chen, L., Staley, J. R., Staplin, N., Altay, S. et al. Circulation 146, 1507-1517 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36314129
Dezember
Paper of the Month
A multicenter evaluation of external outflow graft obstruction with a fully magnetically levitated left ventricular assist device. Wert, L., Stewart, G. C., Mehra, M. R., Milwidsky, A., Jorde, U. P., Goldstein, D. J., Selzman, C. H., Stehlik, J., Alshamdin, F. D., Khaliel, F. H., Gustafsson, F., Boschi, S., Loforte, A., Ajello, S., Scandroglio, A. M., Tucanova, Z., Netuka, I., Schloglhofer, T., Zimpfer, D., Zijderhand, C. F. et al. J Thorac Cardiovasc Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/36562497
Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond. Khan, E. S. & Danckwardt, S. Genes (Basel) 13 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36553448
Endothelial Cell GATA2 Modulates the Cardiomyocyte Stress Response through the Regulation of Two Long Non-Coding RNAs. Froese, N., Szaroszyk, M., Korf-Klingebiel, M., Koch, K., Schmitto, J. D., Geffers, R., Hilfiker-Kleiner, D., Riehle, C., Wollert, K. C., Bauersachs, J. & Heineke, J. Biology (Basel) 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36552246
A Simplified Approach to Pulmonary Vein Visualization during Cryoballoon Ablation of Atrial Fibrillation. Anwar, O., Chung, D. U., Gunawardene, M. A., Jungen, C., Hartmann, J., Meyer, C., Gessler, N., Willems, S., Hakmi, S. & Eickholt, C. Medicina (Kaunas) 58 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36556902
Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-beta1 driven fibrotic remodeling in ischemic heart failure. Garlapati, V., Molitor, M., Michna, T., Harms, G. S., Finger, S., Jung, R., Lagrange, J., Efentakis, P., Wild, J., Knorr, M., Karbach, S., Wild, S., Vujacic-Mirski, K., Munzel, T., Daiber, A., Brandt, M., Gori, T., Milting, H., Tenzer, S., Ruf, W. et al. J Clin Invest (2022). https://www.ncbi.nlm.nih.gov/pubmed/36548062
Editorial: Nanodomain regulation of muscle physiology and alterations in disease. Louch, W. E., Ullrich, N. D., Navedo, M. F. & Macquaide, N. Front Physiol 13, 1092304 (2022). www.ncbi.nlm.nih.gov/pubmed/36523550
Hypothermia and its role in patients with ST-segment-elevation myocardial infarction and cardiac arrest. Keller, K., Sagoschen, I., Schmitt, V. H., Munzel, T., Gori, T. & Hobohm, L. Front Cardiovasc Med 9, 1051978 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36523354
Editorial: Modeling of cardiovascular systems. Wang, Y., Majumder, R., Tian, F. B. & Gao, X. Front Physiol13, 1094146 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36518103
An electrochemical nitric oxide generator for in-home inhalation therapy in pulmonary artery hypertension. Liu, Y., Zhu, Y., Jiang, C., Su, Z., Yan, Y., Feng, B., Mao, W., Zhang, Y., Wang, X., Xu, Z. & Zhang, H. BMC Med 20, 481 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36522645
Diagnostic and Prognostic Significance of the Prothrombin Time/International Normalized Ratio in Sepsis and Septic Shock. Schupp, T., Weidner, K., Rusnak, J., Jawhar, S., Forner, J., Dulatahu, F., Bruck, L. M., Hoffmann, U., Bertsch, T., Muller, J., Weiss, C., Akin, I. & Behnes, M. Clin Appl Thromb Hemost 28, 10760296221137893 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36503298
Temperature-controlled ablation of the mitral isthmus line using the novel DiamondTemp ablation system. Rottner, L., My, I., Schleberger, R., Moser, F., Moser, J., Kirchhof, P., Ouyang, F., Rillig, A., Metzner, A. & Reissmann, B. Front Cardiovasc Med 9, 1046956 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36505349
The burdens of poverty during the COVID-19 pandemic. Petersen, J., Hettich, N., Baumkotter, R., Wild, P. S., Pfeiffer, N., Munzel, T., Konig, J., Lackner, K. J. & Beutel, M. E. Front Sociol 7, 995318 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36505762
Lack of correlation between hip osteoarthritis and anatomical spinopelvic parameters obtained in supine position on MRI. Maurer, E., Lorbeer, R., Hefferman, G., Schlett, C. L., Peters, A., Rospleszcz, S., Kiefer, L. S., Nikolaou, K., Bamberg, F. & Walter, S. S. Injury 54, 525-532 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36503838
Fetal Bradycardia Caused by Monogenic Disorders-A Review of the Literature. Westphal, D. S., Hauser, M., Beckmann, B. M., Wolf, C. M., Hessling, G., Oberhoffer-Fritz, R. & Wacker-Gussmann, A. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36498454
Subclinical Cardiovascular Disease Markers in Relation to Serum and Dietary Magnesium in Individuals from the General Population: The KORA-MRI Study. Shugaa Addin, N., Schlett, C. L., Bamberg, F., Thorand, B., Linseisen, J., Seissler, J., Peters, A. & Rospleszcz, S. Nutrients 14 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36500983
Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation. Mauersberger, C., Sager, H. B., Wobst, J., Dang, T. A., Lambrecht, L., Koplev, S., Stroth, M., Bettaga, N., Schlossmann, J., Wunder, F., Friebe, A., Björkegren, J. L. M., Dietz, L., Maas, S. L., van der Vorst, E. P. C., Sandner, P., Soehnlein, O., Schunkert, H. & Kessler, T. Nature Cardiovascular Research 1, 1174-1186 (2022). https://www.nature.com/articles/s44161-022-00175-w
Safety and Feasibility of Catheter Ablation Procedures in Patients with Bleeding Disorders. Feher, M., Saguner, A. M., Kirstein, B., Vogler, J., Eitel, C., Phan, H. L., Keelani, A., Cimen, T., Hatahet, S., Trajanoski, D., Samara, O., Kuck, K. H., Tilz, R. R. & Heeger, C. H. J Clin Med 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36498531
Posttraumatic growth after childhood cancer: Psychometric evaluation of a five-item short form and associations with mental health. Ernst, M., Werner, A. M., Brahler, E., Wild, P. S., Faber, J., Merzenich, H. & Beutel, M. E. J Psychosom Res 164, 111099 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36481723
Immuno-cardio-oncology: Killing two birds with one stone? Van Linthout, S. & Volk, H. D. Front Immunol 13, 1018772 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36466820
Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum. Schmidt, J., Dreha-Kulaczewski, S., Zafeiriou, M. P., Schreiber, M. K., Wilken, B., Funke, R., Neuhofer, C. M., Altmuller, J., Thiele, H., Nurnberg, P., Biskup, S., Li, Y., Zimmermann, W. H., Kaulfuss, S., Yigit, G. & Wollnik, B. Front Cell Dev Biol 10, 1025332 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36467423
Pregnancy and breast cancer in a patient with complicated Kawasaki Disease, as if one problem was not enough: a case report. Barzen, G., Stangl, K., Blohmer, J. U., Henrich, W., Dorner, T., Lembcke, A. & Stangl, V. Eur Heart J Case Rep 6, ytac435 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36451807 https://www.ncbi.nlm.nih.gov/pubmed/36451807
Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19. Tran, F., Harris, D. M. M., Scharmacher, A., Grasshoff, H., Sterner, K., Schinke, S., Kading, N., Humrich, J. Y., Cabral-Marques, O., Bernardes, J. P., Mishra, N., Bahmer, T., Franzenburg, J., Hoyer, B. F., Gluck, A., Guggeis, M., Ossysek, A., Kuller, A., Frank, D., Lange, C. et al. ERJ Open Res 8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36575710
Early SARS-CoV-2 infection: platelet-neutrophil complexes and platelet function. Rieder, M., Baldus, N., Stallmann, D., Jeserich, M., Goller, I., Wirth, L., Pollmeier, L., Hofmann, M., Bode, C., Busch, H. J., Schmid, B., Gauchel, N., Scharf, R. E., Duerschmied, D., Lother, A. & Krauel, K. Res Pract Thromb Haemost, 100025 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36575689
De Ritis ratio and long-term major cardiovascular adverse events in patients undergoing elective percutaneous coronary intervention. Ndrepepa, G., Holdenrieder, S. & Kastrati, A. Eur J Clin Invest, e13942 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36575818
Brown adipose tissue is not associated with cachexia or increased mortality in a retrospective study of patients with cancer. Eljalby, M., Huang, X., Becher, T., Wibmer, A. G., Jiang, C. S., Vaughan, R., Schoder, H. & Cohen, P. Am J Physiol Endocrinol Metab (2022). https://www.ncbi.nlm.nih.gov/pubmed/36576355
Expanding the spectrum of EEF1D neurodevelopmental disorders: Biallelic variants in the Guanine Exchange Domain. Averdunk, L., Al-Thihli, K., Surowy, H., Ludecke, H. J., Drechsler, M., Yigit, G., Smorag, L., Hallak, B. A., Li, Y., Altmuller, J., Guthoff, T., Wallot, M., Nurnberg, P., Wollnik, B., Abou Jamra, R., Al-Maawali, A. & Wieczorek, D. Clin Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/36576126
Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway. Ying, Z., van Eenige, R., Beerepoot, R., Boon, M. R., Kloosterhuis, N. J., van de Sluis, B., Bartelt, A., Rensen, P. C. N. & Kooijman, S. Pharmacol Res 187, 106634 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36574856
Heart-Focused Anxiety Is Prevalent in Adults With Congenital Heart Disease and Associated With Reduced Exercise Capacity. Willinger, L., Hock, J., Hager, A., Oberhoffer-Fritz, R., Ewert, P. & Muller, J. J Cardiopulm Rehabil Prev (2022). https://www.ncbi.nlm.nih.gov/pubmed/36574070
Have extraction patterns in German adults with severe periodontitis changed between 2000 and 2010? Results from two cohort studies. Rug, J., Holtfreter, B., Volzke, H. & Kocher, T. J Clin Periodontol(2022). https://www.ncbi.nlm.nih.gov/pubmed/36574775
A single-cell RNA labeling strategy for measuring stress response upon tissue dissociation. Neuschulz, A., Bakina, O., Badillo-Lisakowski, V., Olivares-Chauvet, P., Conrad, T., Gotthardt, M., Kettenmann, H. & Junker, J. P. Mol Syst Biol, e11147 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36573354
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. Kanoni, S., Graham, S. E., Wang, Y., Surakka, I., Ramdas, S., Zhu, X., Clarke, S. L., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C. et al. Genome Biol 23, 268 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36575460
Pooled analysis of epigenome-wide association studies of food consumption in KORA, TwinsUK and LLS. Hellbach, F., Sinke, L., Costeira, R., Baumeister, S. E., Beekman, M., Louca, P., Leeming, E. R., Mompeo, O., Berry, S., Wilson, R., Wawro, N., Freuer, D., Hauner, H., Peters, A., Winkelmann, J., Koenig, W., Meisinger, C., Waldenberger, M., Heijmans, B. T., Slagboom, P. E. et al. Eur J Nutr (2022). https://www.ncbi.nlm.nih.gov/pubmed/36571600
Co-exposure to urban particulate matter and aircraft noise adversely impacts the cerebro-pulmonary-cardiovascular axis in mice. Kuntic, M., Kuntic, I., Krishnankutty, R., Gericke, A., Oelze, M., Junglas, T., Bayo Jimenez, M. T., Stamm, P., Nandudu, M., Hahad, O., Keppeler, K., Daub, S., Vujacic-Mirski, K., Rajlic, S., Strohm, L., Ubbens, H., Tang, Q., Jiang, S., Ruan, Y., Macleod, K. G. et al. Redox Biol 59, 102580 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36566737
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause. Khan, M. S., Butler, J., Anker, S. D., Filippatos, G., Ferreira, J. P., Pocock, S. J., Januzzi, J. L., Pina, I. L., Bohm, M., Ponikowski, P., Verma, S., Brueckmann, M., Vedin, O., Zeller, C., Zannad, F. & Packer, M. J Am Heart Assoc, e027652 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36565199
Prognostic Impact of Different Types of Ventricular Tachyarrhythmias Stratified by Underlying Cardiac Disease. Schupp, T., Rusnak, J., Weidner, K., Bertsch, T., Mashayekhi, K., Tajti, P., Akin, I. & Behnes, M. J Pers Med 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36556245
Impact of Lactate on 30-Day All-Cause Mortality in Patients with and without Out-of-Hospital Cardiac Arrest Due to Cardiogenic Shock. Rusnak, J., Schupp, T., Weidner, K., Ruka, M., Egner-Walter, S., Forner, J., Bertsch, T., Kittel, M., Mashayekhi, K., Tajti, P., Ayoub, M., Behnes, M. & Akin, I. J Clin Med 11(2022). https://www.ncbi.nlm.nih.gov/pubmed/36555911
Right Ventricular Strain by Magnetic Resonance Feature Tracking Is Largely Afterload-Dependent and Does Not Reflect Contractility: Validation by Combined Volumetry and Invasive Pressure Tracings. Rolf, A., Keller, T., Wolter, J. S., Kriechbaum, S., Weferling, M., Guth, S., Wiedenroth, C., Mayer, E., Hamm, C. W., Fischer-Rasokat, U. & Treiber, J. Diagnostics (Basel) 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36553190
Genetic Ablation of Ankrd1 Mitigates Cardiac Damage during Experimental Autoimmune Myocarditis in Mice. Rinkunaite, I., Simoliunas, E., Alksne, M., Bartkute, G., Labeit, S., Bukelskiene, V. & Bogomolovas, J. Biomolecules 12 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36551326
Quo Vadis? Immunodynamics of Myeloid Cells after Myocardial Infarction. Moggio, A., Schunkert, H., Kessler, T. & Sager, H. B. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36555456
Body surface scan anthropometrics are related to cardiorespiratory fitness in the general population. Kohler, A., Filges, B., Volzke, H., Felix, S. B., Ewert, R., Stubbe, B., Markus, M. R. P., Gross, S., Dorr, M., Ittermann, T. & Bahls, M. Sci Rep 12, 22185 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36564547
Differential Regulation of MMPs, Apoptosis and Cell Proliferation by the Cannabinoid Receptors CB1 and CB2 in Vascular Smooth Muscle Cells and Cardiac Myocytes. Greiner, B., Sommerfeld, M., Kintscher, U., Unger, T., Kappert, K. & Kaschina, E. Biomedicines 10 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36552027
tRNA-like Transcripts from the NEAT1-MALAT1 Genomic Region Critically Influence Human Innate Immunity and Macrophage Functions. Gast, M., Nageswaran, V., Kuss, A. W., Tzvetkova, A., Wang, X., Mochmann, L. H., Rad, P. R., Weiss, S., Simm, S., Zeller, T., Voelzke, H., Hoffmann, W., Volker, U., Felix, S. B., Dorr, M., Beling, A., Skurk, C., Leistner, D. M., Rauch, B. H., Hirose, T. et al. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36552736
Effect of Metabolic Adaptation by Voluntary Running Wheel Activity and Aldosterone Inhibition on Renal Function in Female Spontaneously Hypertensive Rats. Atmanspacher, F., Schreckenberg, R., Wolf, A., Grgic, I. & Schluter, K. D. Cells 11 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36552716
Effect of baroreflex activation therapy on dipping pattern in patients with resistant hypertension. Wallbach, M., Born, E., Schafer, A. K. & Koziolek, M. J. J Clin Hypertens (Greenwich) (2022). https://www.ncbi.nlm.nih.gov/pubmed/36545753
Heart failure: an update from the last years and a look at the near future. Riccardi, M., Sammartino, A. M., Piepoli, M., Adamo, M., Pagnesi, M., Rosano, G., Metra, M., von Haehling, S. & Tomasoni, D. ESC Heart Fail 9, 3667-3693 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36546712
Successful baroreflex activation therapy in a case of therapy-resistant renovascular hypertension. Nuhn, E. M., Wallbach, M., Elger, F. & Koziolek, M. J. Clin Res Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36547755
Efficacy and Safety of Inclisiran in Patients with Polyvascular Disease: Pooled, Post Hoc Analysis of the ORION-9, ORION-10, and ORION-11 Phase 3 Randomized Controlled Trials. Koenig, W., Conde, L. G., Landmesser, U., Leiter, L. A., Ray, K. K., Schwartz, G. G., Wright, R. S., Han, J. & Raal, F. J. Cardiovasc Drugs Ther (2022). https://www.ncbi.nlm.nih.gov/pubmed/36550348
Very high-power short-duration ablation for pulmonary vein isolation utilizing a very-close protocol-the FAST AND FURIOUS PVI study. Heeger, C. H., Sano, M., Popescu, S. S., Subin, B., Feher, M., Phan, H. L., Kirstein, B., Vogler, J., Eitel, C., Hatahet, S., Kuck, K. H. & Tilz, R. R. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/36546582
Human Macrophage Long Intergenic Noncoding RNA, SIMALR, Suppresses Inflammatory Macrophage Apoptosis via NTN1 (Netrin-1). Cynn, E., Li, D., O'Reilly, M. E., Wang, Y., Bashore, A. C., Jha, A., Foulkes, A., Zhang, H., Winter, H., Maegdefessel, L., Yan, H., Li, M., Ross, L., Xue, C. & Reilly, M. P. Arterioscler Thromb Vasc Biol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36546321
A systematic review and evaluation of statistical methods for group variable selection. Buch, G., Schulz, A., Schmidtmann, I., Strauch, K. & Wild, P. S. Stat Med (2022). https://www.ncbi.nlm.nih.gov/pubmed/36546512
Glucose-Induced Hemodynamic and Metabolic Response of Skeletal Muscle in Heart Failure Patients with Reduced vs. Preserved Ejection Fraction-A Pilot Study. Boschmann, M., Klug, L., Edelmann, F., Sandek, A., von Haehling, S., Dungen, H. D., Springer, J., Anker, S. D., Doehner, W. & Jauert, N. J Cardiovasc Dev Dis 9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36547453
Immature Platelet Fraction Predicts Adverse Events in Patients With Acute Coronary Syndrome: the ISAR-REACT 5 Reticulated Platelet Substudy. Bongiovanni, D., Schreiner, N., Gosetti, R., Mayer, K., Angiolillo, D. J., Sibbing, D., Holdenrieder, S., Anetsberger, A., von Scheidt, M., Schunkert, H., Laugwitz, K. L., Schupke, S., Kastrati, A., Fegers-Wustrow, I. & Bernlochner, I. Arterioscler Thromb Vasc Biol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36546322
Sex-specific associations between serum lipids and hemostatic factors: the cross-sectional population-based KORA-fit study. von Falckenstein, J. V., Freuer, D., Peters, A., Heier, M., Teupser, D., Linseisen, J. & Meisinger, C. Lipids Health Dis 21, 143 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36544148
Coronary artery perforation located in a coronary artery bypass graft treated with new-generation single-layer polytetrafluorethylene-covered stent: results from a multicenter Registry. Voll, F., Koch, T., Lenz, T., Cassese, S., Xhepa, E., Joner, M., Kastrati, A., Kufner, S. & Investigators, R. Coron Artery Dis(2022). https://www.ncbi.nlm.nih.gov/pubmed/36539951
The molecular evolution of spermatogenesis across mammals. Murat, F., Mbengue, N., Winge, S. B., Trefzer, T., Leushkin, E., Sepp, M., Cardoso-Moreira, M., Schmidt, J., Schneider, C., Mossinger, K., Bruning, T., Lamanna, F., Belles, M. R., Conrad, C., Kondova, I., Bontrop, R., Behr, R., Khaitovich, P., Paabo, S., Marques-Bonet, T. et al. Nature (2022). https://www.ncbi.nlm.nih.gov/pubmed/36544022
Mansoor's Self-Report Tool for Cardiovascular Risk Assessment predicts adverse in-hospital events in patients with pulmonary embolism. Keller, K., Schmitt, V. H., Ostad, M. A., Munzel, T., Hobohm, L. & Espinola-Klein, C. Clin Respir J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36544042
Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. Wu, F., Li, X., Looso, M., Liu, H., Ding, D., Gunther, S., Kuenne, C., Liu, S., Weissmann, N., Boettger, T., Atzberger, A., Kolahian, S., Renz, H., Offermanns, S., Gartner, U., Potente, M., Zhou, Y., Yuan, X. & Braun, T. Nat Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/36539616
The effect of probiotic and synbiotic supplementation on appetite-regulating hormones and desire to eat: A systematic review and meta-analysis of clinical trials. Noormohammadi, M., Ghorbani, Z., Lober, U., Mahdavi-Roshan, M., Bartolomaeus, T. U. P., Kazemi, A., Shoaibinobarian, N. & Forslund, S. K. Pharmacol Res 187, 106614 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36538981
Single-cell transcriptomics for the assessment of cardiac disease. Miranda, A. M. A., Janbandhu, V., Maatz, H., Kanemaru, K., Cranley, J., Teichmann, S. A., Hubner, N., Schneider, M. D., Harvey, R. P. & Noseda, M. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36539452
Noise annoyance and risk of prevalent and incident atrial fibrillation-A sex-specific analysis. Hahad, O., Beutel, M. E., Gilan, D. A., Chalabi, J., Schuster, A. K., Gianicolo, E., Lackner, K. J., Lieb, K., Galle, P. R., Wild, P. S., Daiber, A. & Munzel, T. Front Public Health 10, 1061328 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36536776
The impact of extra-valvular cardiac damage on mid-term clinical outcome following transcatheter aortic valve replacement in patients with severe aortic stenosis. Pellegrini, C., Duesmann, C., Rheude, T., Berg, A., Alvarez-Covarrubias, H. A., Trenkwalder, T., Mayr, N. P., Schurmann, F., Nicol, P., Xhepa, E. & Joner, M. Front Cardiovasc Med 9, 1039208 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36531697
Timing of bioprosthetic valve fracture in transcatheter valve-in-valve intervention: impact on valve durability and leaflet integrity. Meier, D., Payne, G. W., Mostaco-Guidolin, L. B., Bouchareb, R., Rich, C., Lai, A., Chatfield, A. G., Akodad, M., Salcudean, H., Lutter, G., Puehler, T., Pibarot, P., Allen, K. B., Chhatriwalla, A. K., Sondergaard, L., Wood, D. A., Webb, J. G., Leipsic, J. A., Sathananthan, J. & Sellers, S. L. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/36534495
Efficient single copy integration via homology-directed repair (scHDR) by 5'modification of large DNA donor fragments in mice. Medert, R., Thumberger, T., Tavhelidse-Suck, T., Hub, T., Kellner, T., Oguchi, Y., Dlugosz, S., Zimmermann, F., Wittbrodt, J. & Freichel, M. Nucleic Acids Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/36533445
Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling. Lopez, M., Malacarne, P. F., Ramanujam, D. P., Warwick, T., Muller, N., Hu, J., Dewenter, M., Weigert, A., Gunther, S., Gilsbach, R., Engelhardt, S., Brandes, R. P. & Rezende, F. Front Physiol 13, 1056369 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36531184
New prospectives on treatment opportunities in RASopathies. Gelb, B. D., Yohe, M. E., Wolf, C. & Andelfinger, G. Am J Med Genet C Semin Med Genet (2022). https://www.ncbi.nlm.nih.gov/pubmed/36533679
3D modeling and printing for complex biventricular repair of double outlet right ventricle. Bruning, J., Kramer, P., Goubergrits, L., Schulz, A., Murin, P., Solowjowa, N., Kuehne, T., Berger, F., Photiadis, J. & Weixler, V. H. Front Cardiovasc Med 9, 1024053 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36531701
Interferon-gamma drives macrophage reprogramming, cerebrovascular remodeling, and cognitive dysfunction in a zebrafish and a mouse model of ion imbalance and pressure overload. Apaydin, D. C., Zakarauskas-Seth, B. I., Carnevale, L., Apaydin, O., Perrotta, M., Carnevale, R., Kotini, M. P., Kotlar-Goldaper, I., Belting, H. G., Carnevale, D., Filosa, A. & Sawamiphak, S. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/36536484
Straight to the Heart: T Cells That Specifically Target Cardiac Tissue. Abplanalp, W. T., Merten, M. & Dimmeler, S. Circulation 146, 1946-1949 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36534731
Results of non-elective withdrawal of continuous-flow left ventricular assist devices in selected patients. Knierim, J., Tsyganenko, D., Stein, J., Mulzer, J., Muller, M., Hrytsyna, Y., Schoenrath, F., Falk, V. & Potapov, E. J Heart Lung Transplant (2022). https://www.ncbi.nlm.nih.gov/pubmed/36529649
Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting. Anttila, V., Saraste, A., Knuuti, J., Hedman, M., Jaakkola, P., Laugwitz, K. L., Krane, M., Jeppsson, A., Sillanmaki, S., Rosenmeier, J., Zingmark, P., Rudvik, A., Garkaviy, P., Watson, C., Pangalos, M. N., Chien, K. R., Fritsche-Danielson, R., Collen, A. & Gan, L. M. Mol Ther (2022). https://www.ncbi.nlm.nih.gov/pubmed/36528793
The '10 commandments' for the 2022 European Society of Cardiology guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery. Mehilli, J. & Halvorsen, S. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36527277
Myocardial epigenetic modifications link chronic kidney disease to coronary microvascular disease. Sen, P., Sorop, O. & Merkus, D. Am J Physiol Heart Circ Physiol 324, H175-H176 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36525479
Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its host. Midha, A., Jarquin-Diaz, V. H., Ebner, F., Lober, U., Hayani, R., Kundik, A., Cardilli, A., Heitlinger, E., Forslund, S. K. & Hartmann, S. Microbiome 10, 229 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36527132
Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy. Juretzko, A., Steinbach, A., Witte, J., Hannemann, A., Miehe, B., Siegerist, F., Wolke, C., Stracke, S. & Rettig, R. Pflugers Arch (2022). https://www.ncbi.nlm.nih.gov/pubmed/36520238
Macrophagic AMPKalpha1 orchestrates regenerative inflammation induced by glucocorticoids. Caratti, G., Desgeorges, T., Juban, G., Stiffel, U., Fessard, A., Koenen, M., Caratti, B., Theret, M., Skurk, C., Chazaud, B., Tuckermann, J. P. & Mounier, R. EMBO Rep, e55363 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36520372
Berlin Registry of Neuroimmunological entities (BERLimmun): protocol of a prospective observational study. Sperber, P. S., Brandt, A. U., Zimmermann, H. G., Bahr, L. S., Chien, C., Rekers, S., Mahler, A., Bottcher, C., Asseyer, S., Duchow, A. S., Bellmann-Strobl, J., Ruprecht, K., Paul, F. & Schmitz-Hubsch, T. BMC Neurol 22, 479 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36517734
Comment to the article: "Consensus statement on the definition of orthostatic hypertension endorsed by the American Autonomic Society and the Japanese Society of Hypertension" by Jordan and colleagues. Moreno Velasquez, I. & Pischon, T. Clin Auton Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/36517690
Prior Myocardial Infarction and Treatment Effect of Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndromes - A Post-hoc Analysis of the ISAR-REACT 5 Trial. Lahu, S., Scalamogna, M., Ndrepepa, G., Menichelli, M., Valina, C., Hemetsberger, R., Witzenbichler, B., Bernlochner, I., Joner, M., Xhepa, E., Hapfelmeier, A., Kufner, S., Sager, H. B., Mayer, K., Kessler, T., Laugwitz, K. L., Richardt, G., Schunkert, H., Neumann, F. J., Kastrati, A. et al. J Am Heart Assoc 11, e027257 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36515247
Early rhythm-control therapy for atrial fibrillation in patients with a history of stroke: a subgroup analysis of the EAST-AFNET 4 trial. Jensen, M., Suling, A., Metzner, A., Schnabel, R. B., Borof, K., Goette, A., Haeusler, K. G., Zapf, A., Wegscheider, K., Fabritz, L., Diener, H. C., Thomalla, G. & Kirchhof, P. Lancet Neurol 22, 45-54 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36517170
Initial experience with transcatheter tricuspid valve repair in patients with cardiac amyloidosis. Hoerbrand, I. A., Volz, M. J., Aus dem Siepen, F., Aurich, M., Schlegel, P., Geis, N. A., Hegenbart, U., Konstandin, M. H., Frey, N. & Raake, P. W. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36514259
Furnishing the cachexia landscape: A year of research in JCSM. Frohlich, A. K., Diek, M., von Haehling, S. & Anker, M. S. J Cachexia Sarcopenia Muscle 13, 2763-2771 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36510825
Long non-coding RNAs at the crossroad of vascular smooth muscle cell phenotypic modulation in atherosclerosis and neointimal formation. Fasolo, F., Paloschi, V. & Maegdefessel, L. Atherosclerosis(2022). https://www.ncbi.nlm.nih.gov/pubmed/36513554
Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment. Betschart, R. O., Thiery, A., Aguilera-Garcia, D., Zoche, M., Moch, H., Twerenbold, R., Zeller, T., Blankenberg, S. & Ziegler, A. Sci Rep 12, 21502 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36513709
Single beta-blocker or combined amiodarone therapy in implantable cardioverter-defibrillator and cardiac resynchronization therapy defibrillator patients - insights from the German DEVICE-registry. Wiedmann, F., Ince, H., Stellbrink, C., Kleemann, T., Eckardt, L., Brachmann, J., Gonska, B. D., Kaab, S., Perings, C. A., Jung, W., Lugenbiel, P., Hochadel, M., Senges, J., Frey, N. & Schmidt, C. Heart Rhythm(2022). https://www.ncbi.nlm.nih.gov/pubmed/36509321
Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide. O'Reilly, M., Sommerfeld, L. C., O'Shea, C., Broadway-Stringer, S., Andaleeb, S., Reyat, J. S., Kabir, S. N., Stastny, D., Malinova, A., Delbue, D., Fortmueller, L., Gehmlich, K., Pavlovic, D., Skryabin, B. V., Holmes, A. P., Kirchhof, P. & Fabritz, L. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/36504385
Impact of observer experience on multi-detector computed tomography aortic valve morphology assessment and valve size selection for transcatheter aortic valve replacement. Evertz, R., Hub, S., Kowallick, J. T., Seidler, T., Danner, B. C., Hasenfuss, G., Toischer, K. & Schuster, A. Sci Rep 12, 21430 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36509862
Cardiac metabolism in HFpEF: from fuel to signalling. Capone, F., Sotomayor-Flores, C., Bode, D., Wang, R., Rodolico, D., Strocchi, S. & Schiattarella, G. G. Cardiovasc Res (2022). https://www.ncbi.nlm.nih.gov/pubmed/36504368
Placental Transcriptome Profiling in Subtypes of Diabetic Pregnancies Is Strongly Confounded by Fetal Sex. Kedziora, S. M., Obermayer, B., Sugulle, M., Herse, F., Kraker, K., Haase, N., Langmia, I. M., Muller, D. N., Staff, A. C., Beule, D. & Dechend, R. Int J Mol Sci 23 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36499721
Telemedical monitoring in patients with inborn cardiac disease - experience of a tertiary care centre. Westphal, D. S., Federle, D., Steger, A., Vodermeier, T., Scheiper-Welling, S., Jenewein, T., Beckmann, B. M., Kauferstein, S., Martens, E. & Hahn, F. Mamm Genome, 1-8 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36481846
Pragmatic screening for heart failure in the general population using an electrocardiogram-based neural network. Surendra, K., Nurnberg, S., Bremer, J. P., Knorr, M. S., Uckert, F., Wenzel, J. P., Bei der Kellen, R., Westermann, D., Schnabel, R. B., Twerenbold, R., Magnussen, C., Kirchhof, P., Blankenberg, S., Neumann, J. & Schrage, B. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36482800
Diagnostic and prognostic role of platelets in patients with sepsis and septic shock. Schupp, T., Weidner, K., Rusnak, J., Jawhar, S., Forner, J., Dulatahu, F., Bruck, L. M., Hoffmann, U., Kittel, M., Bertsch, T., Akin, I. & Behnes, M. Platelets 34, 2131753 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36484263
Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Petter, E., Scheibenbogen, C., Linz, P., Stehning, C., Wirth, K., Kuehne, T. & Kelm, M. J Transl Med 20, 580 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36494667
Sex hormones in SARS-CoV-2 susceptibility: key players or confounders? Lott, N., Gebhard, C. E., Bengs, S., Haider, A., Kuster, G. M., Regitz-Zagrosek, V. & Gebhard, C. Nat Rev Endocrinol, 1-15 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36494595
Impact of age on the prognosis of patients with ventricular tachyarrhythmias and aborted cardiac arrest. Weidner, K., Schupp, T., Rusnak, J., El-Battrawy, I., Ansari, U., Hoppner, J., Mueller, J., Kittel, M., Taton, G., Reiser, L., Bollow, A., Reichelt, T., Ellguth, D., Engelke, N., Grosse Meininghaus, D., Akin, M., Bertsch, T., Akin, I. & Behnes, M. Z Gerontol Geriatr (2022). https://www.ncbi.nlm.nih.gov/pubmed/36480051
Frequency, associated variables, and outcomes of acute myocardial injury according to the fourth Universal Definition of Myocardial Infarction in patients with acute ischemic stroke. Stengl, H., Ganeshan, R., Hellwig, S., Klammer, M. G., von Rennenberg, R., Bohme, S., Audebert, H. J., Nolte, C. H., Endres, M. & Scheitz, J. F. Eur Stroke J 7, 413-420 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36478763
Genetic diversity fuels gene discovery for tobacco and alcohol use. Saunders, G. R. B., Wang, X., Chen, F., Jang, S. K., Liu, M., Wang, C., Gao, S., Jiang, Y., Khunsriraksakul, C., Otto, J. M., Addison, C., Akiyama, M., Albert, C. M., Aliev, F., Alonso, A., Arnett, D. K., Ashley-Koch, A. E., Ashrani, A. A., Barnes, K. C., Barr, R. G. et al. Nature 612, 720-724 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36477530
HeartWare to HeartMate 3 left ventricular assist device exchange via a left lateral thoracotomy. Nersesian, G., Montagner, M., Lanmueller, P., Lewin, D., Van Praet, K. M., Kofler, M., Ott, S., Falk, V. & Potapov, E. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36476648
Fluorescence in situ hybridization and polymerase chain reaction to detect infections of cardiac implantable electronic devices. Just, I. A., Barthel, F., Moter, A., Kikhney, J., Friedrich, A., Wloch, A., Falk, V., Starck, C. & Schoenrath, F. Europace (2022). https://www.ncbi.nlm.nih.gov/pubmed/36477494
Translational opportunities of single-cell biology in atherosclerosis. de Winther, M. P. J., Back, M., Evans, P., Gomez, D., Goncalves, I., Jorgensen, H. F., Koenen, R. R., Lutgens, E., Norata, G. D., Osto, E., Dib, L., Simons, M., Stellos, K., Yla-Herttuala, S., Winkels, H., Bochaton-Piallat, M. L. & Monaco, C. Eur Heart J(2022). https://www.ncbi.nlm.nih.gov/pubmed/36478058
Empagliflozin, irrespective of blood pressure, improves outcomes in heart failure with preserved ejection fraction: the EMPEROR-Preserved trial. Bohm, M., Anker, S., Mahfoud, F., Lauder, L., Filippatos, G., Ferreira, J. P., Pocock, S. J., Brueckmann, M., Saloustros, I., Schuler, E., Wanner, C., Zannad, F., Packer, M. & Butler, J. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36478225
Adipocytes control haematopoiesis and inflammation through CD40 signaling. Reiche, M. E., Poels, K., Bosmans, L. A., Vos, W. G., Van Tiel, C. M., Gijbels, M. J. J., Aarts, S., Den Toom, M., Beckers, L., Weber, C., Atzler, D., Rensen, P. C. N., Kooijman, S. & Lutgens, E. Haematologica (2022). https://www.ncbi.nlm.nih.gov/pubmed/36475519
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants. Aragam, K. G., Jiang, T., Goel, A., Kanoni, S., Wolford, B. N., Atri, D. S., Weeks, E. M., Wang, M., Hindy, G., Zhou, W., Grace, C., Roselli, C., Marston, N. A., Kamanu, F. K., Surakka, I., Venegas, L. M., Sherliker, P., Koyama, S., Ishigaki, K., Asvold, B. O. et al. Nat Genet 54, 1803-1815 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36474045
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease. Widjaja, A. A., Viswanathan, S., Shekeran, S. G., Adami, E., Lim, W. W., Chothani, S., Tan, J., Goh, J. W. T., Chen, H. M., Lim, S. Y., Boustany-Kari, C. M., Hawkins, J., Petretto, E., Hubner, N., Schafer, S., Coffman, T. M. & Cook, S. A. Nat Commun 13, 7497 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36470928
Leaflet-splitting device to prevent coronary artery obstruction in valve-in-valve transcatheter aortic valve implantation. Van Praet, K. M., Klein, C., Kukucka, M., Kempfert, J., Kofler, M., Gerckens, U., Dvir, D., Falk, V. & Unbehaun, A. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36468494
Linking single nucleotide polymorphisms to signaling blueprints in abdominal aortic aneurysms. Lim, C., Pratama, M. Y., Rivera, C., Silvestro, M., Tsao, P. S., Maegdefessel, L., Gallagher, K. A., Maldonado, T. & Ramkhelawon, B. Sci Rep 12, 20990 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36470918
JCAD promotes arterial thrombosis through PI3K/Akt modulation: a translational study. Liberale, L., Puspitasari, Y. M., Ministrini, S., Akhmedov, A., Kraler, S., Bonetti, N. R., Beer, G., Vukolic, A., Bongiovanni, D., Han, J., Kirmes, K., Bernlochner, I., Pelisek, J., Beer, J. H., Jin, Z. G., Pedicino, D., Liuzzo, G., Stellos, K., Montecucco, F., Crea, F. et al. Eur Heart J (2022). https://www.ncbi.nlm.nih.gov/pubmed/36469488
RNA modifications in cardiovascular health and disease. Gatsiou, A. & Stellos, K. Nat Rev Cardiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36471164
Efficacy of empagliflozin in heart failure with preserved versus mid-range ejection fraction: a pre-specified analysis of EMPEROR-Preserved. Anker, S. D., Butler, J., Usman, M. S., Filippatos, G., Ferreira, J. P., Bocchi, E., Bohm, M., Rocca, H. P. B., Choi, D. J., Chopra, V., Chuquiure, E., Giannetti, N., Gomez-Mesa, J. E., Janssens, S., Januzzi, J. L., Gonzalez-Juanatey, J. R., Merkely, B., Nicholls, S. J., Perrone, S. V., Pina, I. L. et al. Nat Med 28, 2512-2520 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36471037
White matter hyperintensities are an independent predictor of cognitive decline 3 years following first-ever stroke-results from the PROSCIS-B study. Ali, H. F., Fast, L., Khalil, A., Siebert, E., Liman, T., Endres, M., Villringer, K. & Kufner, A. J Neurol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36471099
Interleukin-10 -1082 G/A polymorphism and its association with early or severe presentation of coronary artery disease: A systematic review and meta-analysis. Rai, H., Joner, M., Wilson, H., McGovern, L., Richards, G., Colleran, R. & Byrne, R. A. Cytokine 162, 156103 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36463660
Anti-osteopontin therapy leads to improved edema and infarct size in a murine model of ischemic stroke. Spitzer, D., Puetz, T., Armbrust, M., Dunst, M., Macas, J., Croll, F., Plate, K. H., Reiss, Y., Liebner, S., Harter, P. N., Guerit, S. & Devraj, K. Sci Rep 12, 20925 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36463381
Stent imaging on a clinical dual-source photon-counting detector CT system-impact of luminal attenuation and sharp kernels on lumen visibility. Decker, J. A., O'Doherty, J., Schoepf, U. J., Todoran, T. M., Aquino, G. J., Brandt, V., Baruah, D., Fink, N., Zsarnoczay, E., Flohr, T., Schmidt, B., Allmendinger, T., Risch, F., Varga-Szemes, A. & Emrich, T. Eur Radiol (2022). https://www.ncbi.nlm.nih.gov/pubmed/36462045
Hemodynamic Comparison between the Avalus and the Perimount Magna Ease Aortic Bioprosthesis up to 5 Years. Burri, M., Bozini, N., Vitanova, K., Mayr, B., Lange, R. & Gunzinger, R. Thorac Cardiovasc Surg (2022). https://www.ncbi.nlm.nih.gov/pubmed/36462752
Minimally invasive surgical aortic valve replacement via a partial upper ministernotomy. Van Praet, K. M., Nersesian, G., Kukucka, M., Kofler, M., Wert, L., Klein, C., Unbehaun, A., Kempfert, J. & Falk, V. Multimed Man Cardiothorac Surg 2022 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36458810
DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Cattaneo, P., Hayes, M. G. B., Baumgarten, N., Hecker, D., Peruzzo, S., Aslan, G. S., Kunderfranco, P., Larcher, V., Zhang, L., Contu, R., Fonseca, G., Spinozzi, S., Chen, J., Condorelli, G., Dimmeler, S., Schulz, M. H., Heinz, S., Guimaraes-Camboa, N. & Evans, S. M. Nat Commun 13, 7444 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36460641
ACC/AHA/HFSA 2022 and ESC 2021 guidelines on heart failure comparison. Behnoush, A. H., Khalaji, A., Naderi, N., Ashraf, H. & von Haehling, S. ESC Heart Fail (2022). https://www.ncbi.nlm.nih.gov/pubmed/36460629
Targeting Mitochondrial Calcium Handling to Treat Atrial Fibrillation. Voigt, N., Maack, C. & Pronto, J. R. D. J Am Coll Cardiol 80, 2220-2223 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36456052
Pre-procedural oral anticoagulant use is associated with cardiovascular events in women after transcatheter aortic valve replacement: An analysis from the WIN-TAVI cohort. van Bergeijk, K. H., Wykrzykowska, J. J., Sartori, S., Snyder, C., Vogel, B., Tchetche, D., Petronio, A. S., Mehilli, J., Lefevre, T., Presbitero, P., Capranzano, P., Iadanza, A., Sardella, G., Van Mieghem, N. M., Meliga, E., Dumonteil, N., Fraccaro, C., Trabattoni, D., Mikhail, G., Ferrer-Gracia, M. C. et al. Int J Cardiol 372, 40-45 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36455701
Ten-year clinical outcomes of drug-eluting stents with different polymer coating strategies by degree of coronary calcification: a pooled analysis of the ISAR-TEST 4 and 5 randomised trials. Rheude, T., Koch, T., Joner, M., Lenz, T., Xhepa, E., Wiebe, J., Coughlan, J. J., Aytekin, A., Cassese, S., Laugwitz, K. L., Schunkert, H., Kastrati, A. & Kufner, S. EuroIntervention (2022). https://www.ncbi.nlm.nih.gov/pubmed/36453826
Role of phase angle in older adults with focus on the geriatric syndromes sarcopenia and frailty. Norman, K., Herpich, C. & Muller-Werdan, U. Rev Endocr Metab Disord, 1-9 (2022). https://www.ncbi.nlm.nih.gov/pubmed/36456777
Genome Editing in Dyslipidemia and Atherosclerosis. Chen, Z., Lehertshuber, C. & Schunkert, H. Adv Exp Med Biol 1396, 139-156 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36454465
[ESC guidelines 2022 on cardiovascular assessment and management of patients undergoing non-cardiac surgery : What is new?]. Mehilli, J. & Winhard, M. Herz (2022). https://www.ncbi.nlm.nih.gov/pubmed/36449042
Late-stage C-H Functionalization of Tryptophan-Containing Peptides with Thianthrenium Salts: Conjugation and Ligation. Kaplaneris, N., Puet, A., Kallert, F., Pohlmann, J. & Ackermann, L. Angew Chem Int Ed Engl 62, e202216661 (2023). https://www.ncbi.nlm.nih.gov/pubmed/36581584