DZHK Paper of the month

With the Paper of the month the Board of Directors rewards a recent scientific publication of DZHK researchers.

February 2020

Loss of ADAMTS19 causes progressive non-syndromic heart valve disease. Nat Genet (2019), DZHK authors: Philipp Hofmann, Kirstin Hoff, Enrique Audain, Hans-Heiner Kramer, Marc-Phillip Hitz

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January 2020

CRISPR-Mediated Activation of Endogenous Gene Expression in the Postnatal Heart. Circulation Research. DZHK authors: Eric Schoger, Lavanya M. Iyer, Claudia Noack, Shirin Doroudgar, Wolfram-H. Zimmermann, Laura C. Zelarayan,

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December 2019

Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. The Lancet. DZHK authors: Fabian J. Brunner, Christoph Waldeyer, David M. Leistner, Ulf Landmesser, Stefan Blankenberg

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November 2019

Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes. New England Journal of Medicine. DZHK authors: Stefanie Schüpke, Franz-Josef Neumann, Isabell Bernlochner, Christoph Liebetrau, Ibrahim Akin, Ulf Landmesser, Hugo A. Katus, Dirk Sibbing, Marion Janisch, Erion...

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October 2019

Cardiac alpha-Actin (ACTC1) Gene Mutation Causes Atrial-Septal Defects Associated With Late-Onset Dilated Cardiomyopathy. Circulation. Genomic and precision medicine. DZHK authors: Derk Frank, Ashraf Y. Rangrez, Alexander Bernt, Ankush Borlepawar, Wolfram-Hubertus Zimmermann,...

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September 2019

TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation. EMBO Mol Med. DZHK authors: A. Grund, M. Malek Mohammadi, F. A. Trogisch, E. Riechert, M. Völkers, S. Doroudgar, A. Jungmann, H. A. Katus, O. J. Müller, J. Heineke

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August 2019

Application of High-Sensitivity Troponin in Suspected Myocardial Infarction. N Engl J Med. DZHK authors: J.T. Neumann, N.A. Sörensen, M. Mueller‐Hennessen, T. Gori, C. Liebetrau, C. Hamm, H.A. Katus, T. Münzel, U. Landmesser, B. Thorand, A. Peters, T. Keller, P. Wild, E....

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July 2019

Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease. N Engl J Med. DZHK authors: Nagel, Puntmann, Schulz-Menger

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June 2019

The Translational Landscape of the Human Heart. Cell. DZHK authors: van Heesch, Schulz, Faber, Mücke, Diecke, Knosalla, Linke, Rajewsky, Hübner

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May 2019

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature. DZHK authors: Silvestre-Roig, Braster, Froese, Ortega-Gómez, Schumski, Winter, Maegdefessel, Nikolaev, Weber, Soehnlein

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