DZHK Paper of the month

With the Paper of the month the Board of Directors rewards a recent scientific publication of DZHK researchers.

February 2021

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models. Nat Commun 11, 5319 (2020). DZHK authors: Ferdinand le Noble, Rabea Hinkel, Christian Kupatt

Read more

January 2021

Exercise-Stress Real-time Cardiac Magnetic Resonance Imaging for Non-Invasive Characterisation of Heart Failure with Preserved Ejection Fraction: The HFpEF Stress Trial. Circulation. 2021 Jan 21. DZHK authors: Sören J. Backhaus, Torben Lange, Elisabeth F. George, Kristian...

Read more

December 2020

An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility. Circulation (2020), DZHK authors: Alexandra Madsen, Grit Höppner, Julia Krause, Marc N. Hirt, Sandra D. Laufer, Thomas Eschenhagen, Justus Stenzig

Read more

November 2020

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study. European Heart Journal (2020), DZHK authors: David M...

Read more

October 2020

Cells of the adult human heart. Nature 2020, DZHK authors: Henrike Maatz, Daniel Reichart, Barbara McDonough, Norbert Hübner

Read more

September 2020

A Minimal-Invasive Approach for Standardized Induction of Myocardial Infarction in Mice. Circulation Research, DZHK authors: Florian Sicklinger, Yunhang Zhang, Lorenz Lehmann, Mathias H. Konstandin, Hugo A. Katus, Florian Leuschner

Read more

August 2020

Immunothrombotic Dysregulation in COVID-19 Pneumonia is Associated with Respiratory Failure and Coagulopathy. CIRCULATION 28 Jul 2020, DZHK authors: Leo Nicolai, Alexander Leunig, Rainer Kaiser, Tobias Weinberger, Clemens Scherer, Stefan Kääb, Steffen Massberg. Kami Pekayvaz,...

Read more

July 2020

Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis. Science Translational Medicine (2020), DZHK authors: D. Santovito, L. Natarelli, M. Aslani, E. Lutgens, P. von Hundelshausen, S. Steffens, J. Duchene, R.T.A....

Read more

June 2020

Phosphodiesterase 3A and arterial hypertension. Circulation (2020) DZHK authors: M. Ercu*, L. Markó*, C. Schächterle, D. Tsvetkov, T. U. P. Bartolomaeus, N. Hübner, S. K. Forslund, D. N. Müller, M. Gollasch, M. Bader, Friedrich C. Luft** and E. Klussmann**

Read more

May 2020

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy. Nature Medicine, DZHK authors: A. Moretti, P. Hoppmann, A. B. Meier, T. Bozoglu, A. Baehr, C. M. Schneider, D. Sinnecker, K. Klett, F. Abdel Rahman, T....

Read more