Metabolic control of vascular diseases (Stammzellplattform)

The Stem Cell platform of the DZHK in Berlin was established to provide stem cell specific services to scientists of the DZHK to overcome technical obstacles in a field of reprogramming, differentiation and genome editing rapidly growing and full of spectacular innovations.The stem cell platform already established feeder free cultivation system of hiPSC using homemade chemical defined media and different endothelial and cardiac, differentiation protocols in cooperation with the DZHK affiliated groups of Prof. Willnow, Hübner, Sperling, Gerhardt. The stem cell platform also performed genome engineering experiments using Crispr/Cas9 or TALEN mediated gene targeting and derived different disease and non- disease specific patient iPSC lines using different reprogramming techniques.