Functional role of nexilin in dilated cardiomyopathy

Nexilin is one of the key genes, which have recently been identified by our group to play a critical role in cardiomyopathy. Our research interest is the evaluation of the functional role of nexilin in dilated cardiomyopathy (DCM) using constitutive and conditional mouse models as well as cardiomyocytes differentiated from human induced pluripotent stem cells (iPS cells).