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A leaking mitral valve can be repaired surgically or with catheter-based techniques. A so-called mitral valve prolapse is particularly common, in which part of the valve protrudes (prolapses) into the left atrium. The American PRIMARY study investigates which method is most...

This is what ideal medicine would look like: Doctors could specifically alter molecular processes in diseased cells in the body and thus causally cure patients. This is the goal of the German Centers for Health Research (DZG) in the project "Cell type specific targeting for...

DZHK scientists in Mainz have confirmed this assumption in both mice and humans. If humans and animals were exposed to noise pollution in the past, a heart attack suffered later in life healed more poorly.

Evolutionarily young miniproteins are unique in humans, and researchers have recently discovered thousands of them. Writing in Molecular Cell, Norbert Hübner and colleagues from the BIH and other institutions describe the origins of these tiny proteins and explain that they...

Four teams of leading scientists from the UK, Germany and the Netherlands will collaborate on projects to accelerate progress in the detection and treatment of cardiovascular diseases. The British Heart Foundation (BHF), the German Centre for Cardiovascular Research (DZHK) and...

The so-called "gene scissors" CRISPR/Cas9 can be used to specifically modify DNA: Researchers worldwide hope to be able to use it to better combat cancer and hereditary diseases such as congenital heart defects. Scientists at Heidelberg University have now succeeded in optimizing...

For young researchers, leading their junior research group is an important step towards scientific independence. Heart-lung specialist Dr. Jana Grune of the German Heart Center at Charité in Berlin and molecular biologist Dr. Pieterjan Dierickx from the Max Planck Institute for...

A DZHK research team at the University Medical Center Mainz has discovered a new signaling pathway of the coagulation system that controls scar formation after a heart attack. If this signaling pathway could be inhibited, heart attacks could heal with less subsequent damage.

Prof. Benjamin Meder has accepted the call to the W3 professorship "Precision Digital Health" at Heidelberg University. Within the framework of the research professorship, his focus is on molecular and digital biomarkers, the use of artificial intelligence in everyday clinical...

The German Center for Cardiovascular Research is centralizing its biospecimens collections, which are currently stored at 60 sites. Therefore, it is looking for two biobanks as scientific cooperation partners. Applications are now open to all German biobanks.