Publikationen 2024
Hier finden Sie die Publikationen des DZHK. Bitte informieren Sie sich über weitere Publikationen auch auf den Internetseiten der am DZHK beteiligten Forschungseinrichtungen.
Zu den DZHK Paper of the Month
November
Paper of the Month
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts
DZHK-Autor:innen : Anna Myronova, Eleonora Adami, Wolfram H. Zimmermann, Sebastian Diecke, Norbert Hübner
Design and Rationale of MYOFLAME-19 RCT: MYOcardial protection to reduce inFLAMmatory heart disease due to COVID-19 Infection using CMR Endpoints. Puntmann, V. O., Beitzke, D., Kammerlander, A., Voges, I., Gabbert, D. D., Doerr, M., Chamling, B., Bozkurt, B., Kaski, J. C., Spatz, E., Herrmann, E., Rohde, G., DeLeuw, P., Taylor, L., Windemuth-Kieselbach, C., Harz, C., Santiuste, M., Schoeckel, L., Hirayama, J., Taylor, P. C., Berry, C. & Nagel, E. J Cardiovasc Magn Reson, 101121 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39481808
The age pigment lipofuscin causes oxidative stress, lysosomal dysfunction, and pyroptotic cell death. Baldensperger, T., Jung, T., Heinze, T., Schwerdtle, T., Hohn, A. & Grune, T. Free Radic Biol Med 225, 871-880 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39486751
Quantitative flow ratio versus fractional flow reserve for coronary revascularisation guidance (FAVOR III Europe): a multicentre, randomised, non-inferiority trial. Andersen, B. K., Sejr-Hansen, M., Maillard, L., Campo, G., Ramunddal, T., Stahli, B. E., Guiducci, V., Serafino, L. D., Escaned, J., Santos, I. A., Lopez-Palop, R., Landmesser, U., Dieu, R. S., Mejia-Renteria, H., Koltowski, L., Ziubryte, G., Cetran, L., Adjedj, J., Abdelwahed, Y. S., Liu, T., Mogensen, L. J. H., Eftekhari, A., Westra, J., Lenk, K., Casella, G., Belle, E. V., Biscaglia, S., Olsen, N. T., Knaapen, P., Kochman, J., Santos, R. C., Scarsini, R., Christiansen, E. H. & Holm, N. R. Lancet 404, 1835-1846 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39488224
In-hospital bioimpedance-derived total body water predicts short-term cardiovascular mortality and re-hospitalizations in acute decompensated heart failure patients. Faragli, A., Herrmann, A., Cvetkovic, M., Perna, S., Khorsheed, E., Lo Muzio, F. P., La Porta, E., Fassina, L., Gunther, A. M., Oetvoes, J., Dungen, H. D. & Alogna, A. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39495329
Correction: "Re-evaluation of variants of uncertain significance in patients with hereditary arrhythmogenic disorders". Martin, S., Jenewein, T., Geisen, C., Scheiper-Welling, S. & Kauferstein, S. BMC Cardiovasc Disord 24, 609 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39482628
Regional mechanical dyssynchrony and shortened systole are present in people with Takotsubo syndrome. Reil, J. C., Sequeira, V., Reil, G. H., Steendijk, P., Maack, C., Fink, T., Rawish, E., Eitel, I. & Stiermaier, T. Commun Med (Lond) 4, 223 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39487225
Platelet collagen receptors and their role in modulating platelet adhesion patterns and activation on alternatively processed collagen substrates. Lemmens, T. P., Luo, Q., Wielders, S. J. H., Scheijen, J., Al-Nasiry, S., Koenen, R. R., Wenzel, P. & Cosemans, J. Thromb Res 244, 109201 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39499978
A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds. Muller, M., Ludwig, L., Englert, H., Riedl, K. A., Muller, M. C., Hemkemeyer, S. A., Beerens, M., Mailer, R. K., Renne, T., Lang, S., Baumann-Zumstein, P. & Frye, M. Sci Rep 14, 26691 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39496698
The evolving landscape of cardiometabolic diseases. Eroglu, T., Capone, F. & Schiattarella, G. G. EBioMedicine 109, 105447 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39500010
Real-world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study. Nies, R. J., Ney, S., Kindermann, I., Bewarder, Y., Zimmer, A., Knebel, F., Hahn, K., Spethmann, S., Luedike, P., Michel, L., Rassaf, T., Papathanasiou, M., Stork, S., Cejka, V., Polzin, A., Voss, F., Kelm, M., Unsold, B., Meindl, C., Paulus, M., Yilmaz, A., Chamling, B., Morbach, C. & Pfister, R. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39505353
Amyloid-beta metabolism in age-related neurocardiovascular diseases. Aivalioti, E., Georgiopoulos, G., Tual-Chalot, S., Bampatsias, D., Delialis, D., Sopova, K., Drakos, S. G., Stellos, K. & Stamatelopoulos, K. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39527015
Differential Plin5 response to high-fat diet in cardiomyocytes isolated from young and aged mice. Baumgarten, P., Jung, T., Ott, C. & Grune, T. Mech Ageing Dev 222, 112004 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39510385
Phenotyping patients with chronic obstructive pulmonary disease and heart failure. Becher, P. M., Lindberg, F., Benson, L., Hage, C., Dahlstrom, U., Rosenkranz, S., Cosentino, F., Rosano, G. M. C., Blankenberg, S., Kirchhof, P., Braunschweig, F., Lund, L. H. & Savarese, G. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39509556
Endothelial activation and stress index (EASIX) in coronary artery disease: a simplified measure as a promising biomarker. Finke, D., Hund, H., Frey, N., Luft, T. & Lehmann, L. H. Clin Res Cardiol 113, 1775-1777 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39535591
Association of daily physical activity with pulmonary artery pressure in HFpEF and HFmrEF NYHA class III patients: a pilot trial-feasibility and first results. Herrmann, E. J., Lange, D., Hannig, J., Zimmer, G., Gruen, D., Keller, T., Edegran, A., Johnson, L. S., Sossalla, S., Guckert, M. & Assmus, B. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39508889
Pulmonary hypertension in adults with congenital heart defects (ACHDs) in light of the 2022 ESC PAH guidelines-part II: supportive therapy, special situations (pregnancy, contraception, non-cardiac surgery), targeted pharmacotherapy, organ transplantation, special management (shunt lesion, left ventricular disease, univentricular hearts), interventions, intensive care, ACHD follow-up, future perspective. Kaemmerer, H., Diller, G. P., Dahnert, I., Achenbach, S., Eichstaedt, C. A., Eicken, A., Freiberger, A., Freilinger, S., Geiger, R., Gorenflo, M., Grunig, E., Hager, A., Huntgeburth, M., Kaemmerer-Suleiman, A. S., Kozlik-Feldmann, R., Lammers, A. E., Nagdyman, N., Michel, S., Schmidt, K. H., Suleiman, M., Uebing, A., von Scheidt, F., Herberg, U. & Apitz, C. Cardiovasc Diagn Ther 14, 921-934 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39513142
Pulmonary hypertension in adults with congenital heart defects (ACHDs)-in light of the 2022 ESC PAH guidelines-part I: definition, epidemiology, classification, diagnostics, genetics, risk stratification and follow-up, gender aspects. Kaemmerer, H., Diller, G. P., Dahnert, I., Achenbach, S., Eichstaedt, C. A., Eicken, A., Freiberger, A., Freilinger, S., Geiger, R., Gorenflo, M., Grunig, E., Hager, A., Huntgeburth, M., Kaemmerer-Suleiman, A. S., Kozlik-Feldmann, R., Lammers, A. E., Nagdyman, N., Michel, S., Schmidt, K. H., Suleiman, M., Uebing, A., von Scheidt, F., Herberg, U. & Apitz, C. Cardiovasc Diagn Ther 14, 935-948 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39513141
Does atrial fibrillation ablation prevent cardiovascular death, stroke, and heart failure events? Kirchhof, P., Parwani, A. S. & Schenker, N. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/39515504
Early intermittent cholesterol exposure accelerates atherosclerosis: an oscillating amplifier calling for preemptive control. Kral, M., Doring, Y. & Weber, C. Signal Transduct Target Ther 9, 313 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39511160
Bioimpedance Analysis in CKD and HF Patients: A Critical Review of Benefits, Limitations, and Future Directions. La Porta, E., Faragli, A., Herrmann, A., Lo Muzio, F. P., Estienne, L., Nigra, S. G., Bellasi, A., Deferrari, G., Ricevuti, G., Di Somma, S. & Alogna, A. J Clin Med 13 (2024). www.ncbi.nlm.nih.gov/pubmed/39518641
The rise of cochlear gene therapy. Landegger, L. D., Reisinger, E., Lallemend, F., Hage, S. R., Grimm, D. & Cederroth, C. R. Mol Ther (2024). https://www.ncbi.nlm.nih.gov/pubmed/39520052
Author Correction: Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer's disease. Martinelli, F., Heinken, A., Henning, A. K., Ulmer, M. A., Hensen, T., Gonzalez, A., Arnold, M., Asthana, S., Budde, K., Engelman, C. D., Estaki, M., Grabe, H. J., Heston, M. B., Johnson, S., Kastenmuller, G., Martino, C., McDonald, D., Rey, F. E., Kilimann, I., Peters, O., Wang, X., Spruth, E. J., Schneider, A., Fliessbach, K., Wiltfang, J., Hansen, N., WenzelGlanz, Buerger, K., Janowitz, D., Laske, C., Munk, M. H., Spottke, A., Roy, N., Nauck, M., Teipel, S., Knight, R., Kaddurah-Daouk, R. F., Bendlin, B. B., Hertel, J. & Thiele, I. Sci Rep14, 27692 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39532987
Translating evidence into practice: Managing electrolyte imbalances and iron deficiency in heart failure. Sato, R., Koziolek, M. J. & von Haehling, S. Eur J Intern Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39521682
Preventive catheter ablation for ventricular arrhythmias in patients with end-stage heart failure referred for heart transplantation evaluation: Rationale for and design of the CASTLE-VT trial. Sohns, C., Fink, T., Crijns, H., Costard-Jaeckle, A., Marrouche, N. F., Sossalla, S., Schramm, R., El Hamriti, M., Moersdorf, M., Didenko, M., Braun, M., Sciacca, V., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., Sommer, P. & Investigators, C.-V. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39523910
How the brain impacts the heart: lessons from ischaemic stroke and other neurological disorders. Stengl, H., Poller, W. C., Di Vece, D., Templin, C., Endres, M., Nolte, C. H. & Scheitz, J. F. Heart (2024). https://www.ncbi.nlm.nih.gov/pubmed/39515993
Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis. Sun, T., Monjezi, M. R., Xu, X., Yin, C., Habenicht, A. J. R. & Mohanta, S. K. J Vis Exp (2024). https://www.ncbi.nlm.nih.gov/pubmed/39526611
Long-Term Mortality and Impact of Implantation-Associated Factors on the Incidence of Patient-Prosthesis Mismatch After Transcatheter Aortic Valve Implantation in Patients With Small Annuli. Voigtlander-Buschmann, L., von der Heide, I., Gossling, A., Waldschmidt, L., Hannen, L., Grundmann, D., Ludwig, S., Demal, T., Bhadra, O. D., Schofer, N., Reichenspurner, H., Blankenberg, S., Conradi, L., Schaefer, A. & Seiffert, M. Am J Cardiol 236, 23-29 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39515630
Comparative evaluation of 2 pulsed field ablation systems for atrial fibrillation: insights from real-world clinical implementation and short-term outcomes. Zylla, M. M., Mages, C., Rahm, A. K., Wiedmann, F., Schweizer, P. A., Thomas, D., Frey, N. & Lugenbiel, P. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/39515496
Predictors for length of stay after surgical aortic valve replacement. Arndt, N., Demal, T., Bhadra, O. D., Ludwig, S., Grundmann, D., Voigtlaender-Buschmann, L., Waldschmidt, L., Hannen, L., Blankenberg, S., Kirchhof, P., Conradi, L., Reichenspurner, H., Schofer, N. & Schaefer, A. Thorac Cardiovasc Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39537128
An interactive dashboard for analyzing user interaction patterns in the i2b2 clinical data warehouse. Baum, L., Muller, A., Johns, M., Abu Attieh, H., Halilovic, M., Milicevic, V., Neves, D. T., Otte, K., Pasquier, A., Wirth, F. N., Segelitz, P., Schonrath, K., Weber, J. E. & Prasser, F. BMC Med Inform Decis Mak 24, 333 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39529056
Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases. Cervenka, L., Huskova, Z., Kikerlova, S., Gawrys, O., Vackova, S., Skaroupkova, P., Sadowski, J., Miklovic, M., Molnar, M., Taborsky, M., Melenovsky, V. & Bader, M. Hypertens Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39537982
(Multi-) omics studies of ILC2s in inflammation and metabolic diseases. Kral, M., van der Vorst, E. P. C., Weber, C. & Doring, Y. Front Cell Dev Biol 12, 1473616 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39529633
Emerging Imaging Techniques for Atherosclerosis in Systemic Immune-Mediated Inflammatory Conditions. Markousis-Mavrogenis, G., Habib, M., Huck, D. M., Andre, F., Steen, H., Mukherjee, M., Mavrogeni, S. I. & Weber, B. Arterioscler Thromb Vasc Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39540283
Homozygous splice-site variant in ENPP1 underlies generalized arterial calcification of infancy. Noor Ul Ayan, H., Nitschke, Y., Mughal, A. R., Thiele, H., Malik, N. A., Hussain, I., Haider, S. M. I., Rutsch, F., Erdmann, J., Tariq, M., Aherrahrou, Z. & Ahmad, I. BMC Pediatr 24, 733 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39538190
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy. Prieto-Garcia, C., Matkovic, V., Mosler, T., Li, C., Liang, J., Oo, J. A., Haidle, F., Macinkovic, I., Cabrera-Orefice, A., Berkane, R., Giuliani, G., Xu, F., Jacomin, A. C., Tomaskovic, I., Basoglu, M., Hoffmann, M. E., Rathore, R., Cetin, R., Boutguetait, D., Bozkurt, S., Hernandez Canas, M. C., Keller, M., Busam, J., Shah, V. J., Wittig, I., Kaulich, M., Beli, P., Galej, W. P., Ebersberger, I., Wang, L., Munch, C., Stolz, A., Brandes, R. P., Tse, W. K. F., Eimer, S., Stainier, D. Y. R., Legewie, S., Zarnack, K., Muller-McNicoll, M. & Dikic, I. Science 386, 768-776 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39541449
Editorial: Challenges and future perspectives of transcatheter valve interventions. Sherif, M., Trippel, T. D. & Leistner, D. M. Front Cardiovasc Med 11, 1509679 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39529976
Accelerometer-Measured Sedentary Behavior and Risk of Future Cardiovascular Disease. Ajufo, E., Kany, S., Ramo, J. T., Churchill, T. W., Guseh, J. S., Aragam, K. G., Ellinor, P. T. & Khurshid, S. J Am Coll Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39545903
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases. Byrne, R. A. & Kastrati, A. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39543308
Word of caution: clinically apparent coronary spasm following pulsed field cavotricuspid isthmus ablation despite nitroglycerin prophylaxis - a case report. Gunawardene, M. A., Hartmann, J., Tigges, E., Jezuit, J. & Willems, S. Eur Heart J Case Rep8, ytae553 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39545158
Cardiac arrhythmias during and after thoracic irradiation for malignancies. Heckmann, M. B., Munster, J. P., Finke, D., Hund, H., Schunn, F., Debus, J., Mages, C., Frey, N., Rahm, A. K. & Lehmann, L. H. Cardiooncology 10, 81 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39543778
RUNX2 is stabilised by TAZ and drives pulmonary artery calcification and lung vascular remodelling in pulmonary hypertension due to left heart disease. Liu, S. F., Kucherenko, M. M., Sang, P., Li, Q., Yao, J., Nambiar Veetil, N., Gransar, T., Alesutan, I., Voelkl, J., Salinas, G., Grune, J., Simmons, S., Knosalla, C. & Kuebler, W. M. Eur Respir J 64 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39542509
Renin Is Essential for Angiotensin II Formation in the Brain. Rodrigues, A. F., Domenig, O., Garrelds, I. M., Danser, A. H. J., Alenina, N., Poglitsch, M. & Bader, M. J Am Heart Assoc 13, e034209 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39547965
Right bundle branch block in suspected acute coronary syndromes: Diagnostic challenges, treatment and prognosis. Senftinger, J., Sorensen, N. A., Blankenberg, S. & Clemmensen, P. J Electrocardiol 87, 153824 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39546998
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials. Zhang, J. J., Pogwizd, S. M., Fukuda, K., Zimmermann, W. H., Fan, C., Hare, J. M., Bolli, R. & Menasche, P. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39548233
Atmospheric new particle formation identifier using longitudinal global particle number size distribution data. Kecorius, S., Madueno, L., Lovric, M., Racic, N., Schwarz, M., Cyrys, J., Casquero-Vera, J. A., Alados-Arboledas, L., Conil, S., Sciare, J., Ondracek, J., Hallar, A. G., Gomez-Moreno, F. J., Ellul, R., Kristensson, A., Sorribas, M., Kalivitis, N., Mihalopoulos, N., Peters, A., Gini, M., Eleftheriadis, K., Vratolis, S., Jeongeun, K., Birmili, W., Bergmans, B., Nikolova, N., Dinoi, A., Contini, D., Marinoni, A., Alastuey, A., Petaja, T., Rodriguez, S., Picard, D., Brem, B., Priestman, M., Green, D. C., Beddows, D. C. S., Harrison, R. M., O'Dowd, C., Ceburnis, D., Hyvarinen, A., Henzing, B., Crumeyrolle, S., Putaud, J. P., Laj, P., Weinhold, K., Plauskaite, K. & Bycenkiene, S. Sci Data11, 1239 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39550387
ECG, clinical and novel CT-imaging predictors of necessary pacemaker implantation after transfemoral aortic valve replacement. Klambauer, K., Puhr-Westerheide, D., Fabritius, M. P., Kunz, W. G., Dinkel, J., Schmid-Tannwald, C., Utz, C., Grathwohl, F., Fink, N., Rizas, K. D., Ricke, J., Ingrisch, M., Stuber, A. T. & Curta, A. Eur J Radiol 182, 111835 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39549437
Absence of cardiac impairment in patients after SARS-CoV-2 infection: a long-term follow-up study. Salatzki, J., Ochs, A., Weberling, L. D., Heins, J., Zahlten, M., Whayne, J. G., Stehning, C., Giannitsis, E., Denkinger, C. M., Merle, U., Buss, S. J., Steen, H., Andre, F. & Frey, N. J Cardiovasc Magn Reson, 101124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39549839
Temporal trends in characteristics of patients undergoing transcatheter tricuspid edge-to-edge repair for tricuspid regurgitation. Kresoja, K. P., Stolz, L., Schober, A., Rommel, K., Rosch, S., Schlotter, F., Gercek, M., Pauschinger, C., Rottbauer, W., Kassar, M., Goebel, B., Denti, P., Rassaf, T., Barreiro-Perez, M., Boekstegers, P., Zdanyte, M., Adamo, M., Vincent, F., Schlegel, P., von Bardeleben, R. S., Wild, M. G., Toggweiler, S., Konstandin, M. H., van Belle, E., Metra, M., Geisler, T., Estevez-Loureiro, R., Luedike, P., Maisano, F., Lauten, P., Praz, F., Kessler, M., Ruck, A., Kalbacher, D., Rudolph, V., Iliadis, C., Thiele, H., Hausleiter, J., Lurz, P. & Euro, T. R. I. O. EuroIntervention20, 1442-1446 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39552479
Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification. Narayanan, S., Vuckovic, S., Bergman, O., Wirka, R., Verdezoto Mosquera, J., Chen, Q. S., Baldassarre, D., Tremoli, E., Veglia, F., Lengquist, M., Aherahrrou, R., Razuvaev, A., Gigante, B., Bjorck, H. M., Miller, C. L., Quertermous, T., Hedin, U. & Matic, L. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39552248
Cyclin-dependent kinase 13 is indispensable for normal mouse heart development. Waheed-Ullah, Q., Wilsdon, A., Abbad, A., Rochette, S., Bu'Lock, F., Saed, A. A., Hitz, M. P., Brook, J. D. & Loughna, S. J Anat (2024). https://www.ncbi.nlm.nih.gov/pubmed/39556044
Dietary Diversity, Rather Than Quality, Parallels a Reduction in Metabolic Syndrome and a Favorable Gut Microbiome: The Dietary Diversity Score. Wiese, M. L., Frost, F., Bahls, M., von Rheinbaben, S., Ruhlemann, M., Bang, C., Franke, A., Nauck, M., Bulow, R., Volker, U., Volzke, H., Ittermann, T., Lerch, M. M. & Aghdassi, A. A. J Am Nutr Assoc, 1-11 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39556796
Three-year changes in high-sensitivity cardiac troponin-T and total mortality in older adults. Dallmeier, D., Braisch, J., Denkinger, M., Koenig, W. & Rothenbacher, D. Sci Rep 14, 28412 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39557882
Intermittent Hypoxic-Hyperoxic Training During Inpatient Rehabilitation Improves Exercise Capacity and Functional Outcome in Patients With Long Covid: Results of a Controlled Clinical Pilot Trial. Doehner, W., Fischer, A., Alimi, B., Muhar, J., Springer, J., Altmann, C. & Schueller, P. O. J Cachexia Sarcopenia Muscle (2024). https://www.ncbi.nlm.nih.gov/pubmed/39559920
A Novel 2D Echo View to Determine Right Ventricular Lead Position on the Tricuspid Valve Level. Zach, V., Lacour, P., Alasfar, L., Chitroceanu, A. M., da Conceicao, C. R., Morris, D. A., Dreger, H., Blaschke, F. & Schneider-Reigbert, M. Echocardiography 41, e70033 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39558561
The neo-aortic valve in patients with hypoplastic left heart syndrome is largely preserved: a serial follow-up CMR study. Burleigh, A., Gabbert, D. D., Ide, Y. & Voges, I. Front Cardiovasc Med11, 1466982 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39563942
Effects of sodium-glucose co-transporter inhibitors on individual clinical endpoints and quality of life. Liao, J., Chen, Y., Ling, Z., Purerfellner, H., Martinek, M., Derndorfer, M., Niel, J., Ebrahimi, R., Heukaufer, M., Janschel, S., Di Vece, D., Empen, K., Hummel, A., Chamling, B., Futyma, P., Ebrahimi, F., Kiuchi, M. G., Liu, S., Yin, Y., Schratter, A., Acou, W. J., Sommer, P., Schmidt, B., Chun, J. K. R., Meyer, C., Dorr, M., Templin, C. & Chen, S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39564882
The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors. Teichmann, T., Pfluger-Muller, B., Gimenez, V. M. M., Sailer, F., Dirks, H., Zehr, S., Warwick, T., Brettner, F., Munoz-Tello, P., Zimmer, A., Tegeder, I., Thomas, D., Gurke, R., Gunther, S., Heering, J., Proschak, E., Geisslinger, G., Bibli, I. S., Heringdorf, D. M. Z., Manucha, W., Windbergs, M., Knapp, S., Weigert, A., Leisegang, M. S., Kojetin, D. & Brandes, R. P. Br J Pharmacol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39563075
Erythritol and xylitol and cardiovascular disease risk: a growing concern. Witkowski, M. & Hazen, S. L. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39565321
A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease. Derks, W., Rode, J., Collin, S., Rost, F., Heinke, P., Hariharan, A., Pickel, L., Simonova, I., Lazar, E., Graham, E., Jashari, R., Andra, M., Jeppsson, A., Salehpour, M., Alkass, K., Druid, H., Kyriakopoulos, C. P., Taleb, I., Shankar, T. S., Selzman, C. H., Sadek, H., Jovinge, S., Brusch, L., Frisen, J., Drakos, S. & Bergmann, O. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39569515
S100A1ct: A Synthetic Peptide Derived From S100A1 Protein Improves Cardiac Performance and Survival in Preclinical Heart Failure Models. Kehr, D., Ritterhoff, J., Glaser, M., Jarosch, L., Salazar, R. E., Spaich, K., Varadi, K., Birkenstock, J., Egger, M., Gao, E., Koch, W. J., Sauter, M., Freichel, M., Katus, H. A., Frey, N., Jungmann, A., Busch, C., Mather, P. J., Ruhparwar, A., Busch, M., Volkers, M., Wade, R. C. & Most, P. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39569500
Getting Imaging Right: Multimodal Assessment of Right-Sided Heart Function in Patients Undergoing Tricuspid Repair. Orban, M., Karam, N., Stolz, L., Lurz, P. & Hausleiter, J. J Am Coll Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39570244
Author Correction: Subclassification of obesity for precision prediction of cardiometabolic diseases. Coral, D. E., Smit, F., Farzaneh, A., Gieswinkel, A., Tajes, J. F., Sparso, T., Delfin, C., Bauvin, P., Wang, K., Temprosa, M., De Cock, D., Blanch, J., Fernandez-Real, J. M., Ramos, R., Ikram, M. K., Gomez, M. F., Kavousi, M., Panova-Noeva, M., Wild, P. S., van der Kallen, C., Adriaens, M., van Greevenbroek, M., Arts, I., Le Roux, C., Ahmadizar, F., Frayling, T. M., Giordano, G. N., Pearson, E. R. & Franks, P. W. Nat Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39572748
Trametinib alters contractility of paediatric Noonan syndrome-associated hypertrophic myocardial tissue slices. Hamers, J., Sen, P., Murthi, S. R., Papanakli, L., von Stumm, M., Baessato, F., Cleuziou, J., Meierhofer, C., Ewert, P., Dendorfer, A., Merkus, D. & Wolf, C. M. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39573843
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience. Jurgens, S. J., Ramo, J. T., Kramarenko, D. R., Wijdeveld, L., Haas, J., Chaffin, M. D., Garnier, S., Gaziano, L., Weng, L. C., Lipov, A., Zheng, S. L., Henry, A., Huffman, J. E., Challa, S., Ruhle, F., Verdugo, C. D., Krijger Juarez, C., Kany, S., van Orsouw, C. A., Biddinger, K., Poel, E., Elliott, A. L., Wang, X., Francis, C., Ruan, R., Koyama, S., Beekman, L., Zimmerman, D. S., Deleuze, J. F., Villard, E., Tregouet, D. A., Isnard, R., FinnGen, Program, V. A. M. V., Consortium, H., Boomsma, D. I., de Geus, E. J. C., Tadros, R., Pinto, Y. M., Wilde, A. A. M., Hottenga, J. J., Sinisalo, J., Niiranen, T., Walsh, R., Schmidt, A. F., Choi, S. H., Chang, K. M., Tsao, P. S., Matthews, P. M., Ware, J. S., Lumbers, R. T., van der Crabben, S., Laukkanen, J., Palotie, A., Amin, A. S., Charron, P., Meder, B., Ellinor, P. T., Daly, M., Aragam, K. G. & Bezzina, C. R. Nat Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/39572784
Sociodemographic, lifestyle, and medical factors associated with calculated free testosterone concentrations in men: individual participant data meta-analyses. Narinx, N., Marriott, R. J., Murray, K., Adams, R. J., Ballantyne, C. M., Bauer, D. C., Bhasin, S., Biggs, M. L., Cawthon, P. M., Couper, D. J., Dobs, A. S., Flicker, L., Hankey, G. J., Hannemann, A., Wilkening, R., Martin, S. A., Matsumoto, A. M., Ohlsson, C., O'Neill, T. W., Orwoll, E. S., Shores, M. M., Steveling, A., Travison, T. G., Wittert, G. A., Wu, F. C. W., Antonio, L., Vanderschueren, D. & Yeap, B. B. Eur J Endocrinol 191, 523-534 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39575586
General anaesthesia and deep sedation for monopolar pulsed field ablation using a lattice-tip catheter combined with a novel three-dimensional mapping system. Rillig, A., Hirokami, J., Moser, F., Bordignon, S., Rottner, L., Shota, T., My, I., Urbani, A., Lemoine, M., Kheir, J., Schenker, N., Urbanek, L., Govorov, K., Schaack, D., Obergassel, J., Riess, J., Ismaili, D., Kirchhof, P., Ouyang, F., Schmidt, B., Reissmann, B., Chun, K. J. & Metzner, A. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39576055
State of the art and perspectives of gene therapy in heart failure. A scientific statement of the Heart Failure Association of the ESC, the ESC Council on Cardiovascular Genomics and the ESC Working Group on Myocardial & Pericardial Diseases. Van Linthout, S., Stellos, K., Giacca, M., Bertero, E., Cannata, A., Carrier, L., Garcia-Pavia, P., Ghigo, A., Gonzalez, A., Haugaa, K. H., Imazio, M., Lopes, L. R., Most, P., Pollesello, P., Schunkert, H., Streckfuss-Bomeke, K., Thum, T., Tocchetti, C. G., Tschope, C., van der Meer, P., van Rooij, E., Metra, M., Rosano, G. M. C. & Heymans, S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39576264
Additive effect of high transportation noise exposure and socioeconomic deprivation on stress-associated neural activity, atherosclerotic inflammation, and cardiovascular disease events. Abohashem, S., Aldosoky, W., Hahad, O., Civieri, G., Assefa, A., Lau, H. C., Abi-Karam, K., Khalil, M., Louis-Jame, L., Al-Kindi, S., Tawakol, A. & Osborne, M. T. J Expo Sci Environ Epidemiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39578565
Increase in PUFA and protein, and decrease in carbohydrate intake improves liver fat in 12 months and the role of weight loss as a mediator: A randomized controlled trial. Pletsch-Borba, L., Wernicke, C., Machann, J., Meyer, N. M., Huong Nguyen, T., Pohrt, A., Hornemann, S., Gerbracht, C., Pfeiffer, A. F., Spranger, J. & Mai, K. Clin Nutr 43, 361-369 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39577067
m6A sites in the coding region trigger translation-dependent mRNA decay. Zhou, Y., Corovic, M., Hoch-Kraft, P., Meiser, N., Mesitov, M., Kortel, N., Back, H., Naarmann-de Vries, I. S., Katti, K., Obrdlik, A., Busch, A., Dieterich, C., Vanacova, S., Hengesbach, M., Zarnack, K. & Konig, J. Mol Cell 84, 4576-4593 e4512 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39577428
Intra-individual radiomic analysis of pericoronary adipose tissue: Photon-counting detector vs energy-integrating detector CT angiography. Kravchenko, D., Vecsey-Nagy, M., Varga-Szemes, A., Hagar, M. T., Schoepf, U. J., Gnasso, C., Zsarnoczay, E., O'Doherty, J., Caruso, D., Laghi, A., Emrich, T. & Tremamunno, G. Int J Cardiol 420, 132749 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39579791
An In Vitro Assay to Study Platelet Migration Using RGD-Functionalized Avidin-Biotin Tethers. Fan, S., Raude, B. & Gaertner, F. J Vis Exp (2024). www.ncbi.nlm.nih.gov/pubmed/39584677
Transcatheter Tricuspid Valve Replacement. Hausleiter, J., Stolz, L., Lurz, P., Rudolph, V., Hahn, R., Estevez-Loureiro, R., Davidson, C., Zahr, F., Kodali, S., Makkar, R., Cheung, A., Lopes, R. D., Maisano, F., Fam, N., Latib, A., Windecker, S. & Praz, F. J Am Coll Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39580719
Inter-site comparability of 4D flow cardiovascular magnetic resonance measurements in healthy traveling volunteers-a multi-site and multi-magnetic field strength study. Muller, M., Daud, E., Langer, G., Groschel, J., Viezzer, D., Hadler, T., Jin, N., Giese, D., Schmitter, S., Schulz-Menger, J. & Trauzeddel, R. F. Front Cardiovasc Med 11, 1456814 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39582524
Cutibacterium acnes infective endocarditis- An emerging pathogen. Saha, S., Joskowiak, D., Marin-Cuartas, M., De La Cuesta, M., Weber, C., Luehr, M., Petrov, A., Dzilic, E., Sandoval-Boburg, R., Marinos, S. L., Pfeiffer, P., Horke, K. M., Schnackenburg, P., Hertel, N., Awad, G., Wacker, M., Moter, I., Caldonazo, T., Kyashif, T., Peterssen, J., Sill, B., Moter, A., Eichinger, W., Reichenspurner, H., Dohle, D., Popov, A. F., Krane, M., Matschke, K., Wahlers, T., Doenst, T., Borger, M., Misfeld, M. & Hagl, C. Eur J Cardiothorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39585651
Association of Modifiable Lifestyle Risk Factors with High-Sensitivity Troponin T and I Concentrations and Clinical Outcomes. Bay, B., Pieper, L., Gossling, A., Kaatze, K., Kellner, C., Arnold, N., Blaum, C., Rohde, J., Koster, L., Lorenz, T., Zeller, T., Blankenberg, S., Waldeyer, C. & Brunner, F. J. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39587386
Risk factors for intensive care admission in childhood patients with COVID-19 - Results of the German nationwide inpatient sample. Keller, K., Sagoschen, I., Schmitt, V. H., Sivanathan, V., Farmakis, I. T., Hahad, O., Koelmel, S., Schmidt, F. P., Espinola-Klein, C., Konstantinides, S., Munzel, T., Lurz, P. & Hobohm, L. Respir Med 236, 107880 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39586334
[Elevated blood pressure and hypertension : Focus of the 2024 ESC guidelines on risk reduction]. Schmieder, R. S. & Schunkert, H. Herz (2024). https://www.ncbi.nlm.nih.gov/pubmed/39589443
Catheter ablation of atrial fibrillation in women with heart failure with preserved ejection fraction. Zylla, M. M., Leiner, J., Rahm, A. K., Hoffmann, T., Lugenbiel, P., Schweizer, P., Mages, C., Mereles, D., Kieser, M., Scholz, E., Katus, H. A., Frey, N. & Thomas, D. Front Cardiovasc Med 11, 1463815 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39588067
Impact of Overnight Storage of Human Atrial Myocytes on Intracellular Calcium Homeostasis and Electrophysiological Utility. Aceituno, C., Revuelta, D., Jimenez-Sabado, V., Ginel, A., Molina, C. E. & Hove-Madsen, L. Biomolecules 14 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39595591
Atrial Fibrillation in Patients with Very High Risk for Stroke and Adverse Events-Insights from the Observational ARENA Study. Alonso, A., Akin, I., Hochadel, M., Borggrefe, M., Lesch, H., Grau, A., Zahn, R., Lugenbiel, P., Schwarzbach, C. J., Sueselbeck, T., Senges, J. & Fastner, C. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39597789
New cardiovascular biomarkers in patients with advanced cancer - A prospective study comparing MR-proADM, MR-proANP, copeptin, high-sensitivity troponin T and NT-proBNP. Anker, M. S., Luck, L. C., Khan, M. S., Porthun, J., Hadzibegovic, S., Lena, A., Wilkenshoff, U., Weinlander, P., Evertz, R., Totzeck, M., Mahabadi, A. A., Rassaf, T., Anker, S. D., Bullinger, L., Keller, U., Karakas, M., Landmesser, U., Butler, J. & von Haehling, S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39600145
Impaired Kidney Function and 10-Year Outcome After Percutaneous Coronary Intervention-Interaction with Age, Sex, Diabetic Status and Clinical Presentation. Ndrepepa, G., Kufner, S., Cassese, S., Joner, M., Sager, H. B., Xhepa, E., Laugwitz, K. L., Schunkert, H. & Kastrati, A. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39597977
Subtle signs of atrial cardiomyopathy and left ventricular diastolic dysfunction are associated with reduced cognitive function: results from the Hamburg City Health Study. Ohlrogge, A. H., Camen, S., Nagel, L., Brederecke, J., Jensen, M., Stenmans, E., Engler, D., Schulte, C., Albrecht, J., Csengeri, D., Kirchhof, P., Cheng, B., Petersen, M., Mayer, C., Borschel, C. S., Wenzel, J. P., Blankenberg, S., Kuhn, S., Thomalla, G. & Schnabel, R. B. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39601872
Peptide Receptor Radionuclide Therapy Using (90)Y- and (177)Lu-DOTATATE Modulating Atherosclerotic Plaque Inflammation: Longitudinal Monitoring by (68)Ga-DOTATATE Positron Emissions Tomography/Computer Tomography. Rubinstein, G., Ilhan, H., Bartenstein, P., Lehner, S., Hacker, M., Todica, A., Zacherl, M. J. & Fischer, M. Diagnostics (Basel) 14 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39594152
Palmitic acid and eicosapentaenoic acid supplementation in 3T3 adipocytes: impact on lipid storage and oxidative stress. Bakondi, E., Jung, T., Marg, S., Schnell, V., Weber, D., Schulz, T. J., Grune, T. & Hohn, A. Redox Rep 29, 2430882 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39607809
Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals. de Kort, F. A. S., Vinke, E. J., van der Lelij, E. J., Anblagan, D., Bastin, M. E., Beiser, A., Brodaty, H., Chaturvedi, N., Cheng, B., Cox, S. R., DeCarli, C., Enzinger, C., Fletcher, E., Frayne, R., de Groot, M., Huang, F., Ikram, M. A., Jiang, J., Lam, B. Y. K., Maillard, P., Mayer, C., McCreary, C. R., Mok, V., Maniega, S. M., Petersen, M., Roshchupkin, G., Sachdev, P. S., Schmidt, R., Seiler, S., Seshadri, S., Sudre, C. H., Thomalla, G., Twerenbold, R., Valdes Hernandez, M., Vernooij, M. W., Wardlaw, J. M., Wen, W., Kuijf, H. J., Biessels, G. J. & Biesbroek, J. M. Neurobiol Aging 146, 38-47 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39602940
Impact of Measured and Predicted Prosthesis-Patient Mismatch After Transcatheter Aortic Valve Replacement. Guthoff, H., Abdel-Wahab, M., Kim, W. K., Witberg, G., Wienemann, H., Thurow, M., Shamekhi, J., Eckel, C., von der Heide, I., Veulemans, V., Landt, M., Barbanti, M., Finkelstein, A., Schewel, J., Van Mieghem, N., Adrichem, R., Toggweiler, S., Rheude, T., Nombela-Franco, L., Amat-Santos, I. J., Ruile, P., Estevez-Loureiro, R., Bunc, M., Branca, L., De Backer, O., Tarantini, G., Mylotte, D., Arzamendi, D., Pauly, M., Bleiziffer, S., Renker, M., Al-Kassou, B., Mollmann, H., Ludwig, S., Zeus, T., Tamburino, C., Schmidt, T., Ruck, A., von Stein, P., Thiele, H., Abdelhafez, A., Adam, M., Baldus, S., Rudolph, T., Mauri, V. & Investigators, I. T. JACC Cardiovasc Interv 17, 2626-2635 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39603776
Mechanisms of repair failure after mitral valve repair using chordal replacement. Lang, M., Feirer, N., Voss, B., Geirsson, A., Amabile, A., Krane, M. & Vitanova, K. Ann Thorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39603581
Urinary Dickkopf-3 as a Potential Marker for Estimated Glomerular Filtration Rate Decline in Patients With Heart Failure. Pieper, D., Sandek, A., Schafer, A. K., Dihazi, H., Dihazi, G. H., Leha, A., Zeisberg, M., Luders, S., Koziolek, M. & Wallbach, M. J Am Heart Assoc13, e036637 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39604022
Unraveling the RNA code: a uridine RNA modification drives glycoRNA biogenesis. Sachse, M. & Stellos, K. Signal Transduct Target Ther 9, 334 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39604375
Long-Term Prognosis of Coronary Aneurysms: Insights of CAAR, an International Registry. Sanchez-Sanchez, I., Cerrato, E., Bollati, M., Espejo-Paeres, C., Nombela-Franco, L., Alfonso-Rodriguez, E., Camacho-Freire, S. J., Villablanca, P. A., Amat-Santos, I. J., De la Torre Hernandez, J. M., Pascual, I., Liebetrau, C., Camacho, B., Pavani, M., Albistur, J., Latini, R. A., Varbella, F., Jimenez Diaz, V. A., Piraino, D., Mancone, M., Alfonso, F., Linares, J. A., Rodriguez-Olivares, R., Jimenez-Mazuecos, J. M., Palazuelos Molinero, J., Sanchez-Grande Flecha, A., Gomez-Hospital, J. A., Ielasi, A., Lozano, I., Omede, P., Feltes, G., Ugo, F., Medda, M., Ramakrishna, H., Kala, P., Bautista, D., Alkhouli, M., Fernandez-Ortiz, A., Nunez-Gil, I. J. & Investigators, C. JACC Cardiovasc Interv 17, 2681-2691 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39603781
Acetylation alchemy: how Nat10 shapes vascular health. Warwick, T., Kurian, L. & Brandes, R. P. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39607798
Prevalence trends of type 2 diabetes treatment, dyslipidemia and hepatic steatosis in Northeast Germany. Bashir, A., Volzke, H., Henck, V., Schipf, S., Dorr, M., Nauck, M., Schmidt, C. O., Aghdassi, A., Khattak, M. N. K., Markus, M. R. P. & Ittermann, T. J Public Health (Oxf) (2024). https://www.ncbi.nlm.nih.gov/pubmed/39611572
Tripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca(2+) channel may modulate its beta-adrenergic regulation. Oz, S., Keren-Raifman, T., Sharon, T., Subramaniam, S., Pallien, T., Katz, M., Tsemakhovich, V., Sholokh, A., Watad, B., Tripathy, D. R., Sasson, G., Chomsky-Hecht, O., Vysochek, L., Schulz-Christian, M., Fecher-Trost, C., Zuhlke, K., Bertinetti, D., Herberg, F. W., Flockerzi, V., Hirsch, J. A., Klussmann, E., Weiss, S. & Dascal, N. BMC Biol 22, 276 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39609812
(13)C Stable Isotope Tracing Reveals Distinct Fatty Acid Oxidation Pathways in Proliferative vs. Oxidative Cells. Ritterhoff, J., McMillen, T., Foundas, H., Palkovacs, R., Poschet, G., Caudal, A., Liu, Y., Most, P., Walker, M. & Tian, R. Am J Physiol Cell Physiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39611618
flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response. Wang, Z. Y., Mehra, A., Wang, Q. C., Gupta, S., Ribeiro da Silva, A., Juan, T., Gunther, S., Looso, M., Detleffsen, J., Stainier, D. Y. R. & Marin-Juez, R. Development 151 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39612288
Gadolinium leakage into ocular structures as a marker in stroke: A retrospective analysis of the WAKE-UP trial. Wouters, A., Van Assche, T., Scheldeman, L., Cheng, B., Simonsen, C. Z., Ebinger, M., Nighoghossian, N., Muir, K. W., Endres, M., Fiebach, J. B., Pedraza, S., Gerloff, C., Thijs, V., Thomalla, G. & Lemmens, R. Eur Stroke J, 23969873241301276 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39611442
Authors' Reply: The University Medicine Greifswald's Trusted Third Party Dispatcher: State-of-the-Art Perspective Into Comprehensive Architectures and Complex Research Workflows. Wundisch, E., Hufnagl, P., Brunecker, P., Meier Zu Ummeln, S., Trager, S., Prasser, F. & Weber, J. JMIR Med Inform 12, e67429 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39612473
Progress of angiographic cardiac allograft vasculopathy in long-term transplanted patients: Longitudinal evaluation of its association with dyslipidemia patterns. Grundmann, D., Neubarth-Mayer, J., Muller, C., Becker, F., Reichart, D., Stark, K., Grabmaier, U., Deseive, S., Rizas, K. D., Hausleiter, J., Hagl, C., Mehilli, J., Massberg, S. & Orban, M. Am J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39613280
Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits. Wang, T., Homberg, J. R., Boreggio, L., Samina, M. C. F., Castro, R. C. R., Kolk, S. M., Alenina, N., Bader, M., Dai, J. & Wohr, M. Mol Autism 15, 50 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39614401
Oktober
Paper of the Month
Macrophage-Expressed Coagulation Factor VII Promotes Adverse Cardiac Remodeling
DZHK-Autor:innen : Venkata Garlapati, Qi Luo, Melania Aluia, Michael Molitor, Stefanie Finger, Wolfram Ruf, Philip Wenzel
Exposure to aircraft noise exacerbates cardiovascular and oxidative damage in three mouse models of diabetes. Mihalikova, D., Stamm, P., Kvandova, M., Pednekar, C., Strohm, L., Ubbens, H., Oelze, M., Kuntic, M., Witzler, C., Bayo Jimenez, M. T., Rajlic, S., Frenis, K., Tang, Q., Ruan, Y., Karbach, S., Kleinert, H., Hahad, O., von Kriegsheim, A., Xia, N., Grune, T., Li, H., Kroller-Schon, S., Gericke, A., Ruf, W., Wild, P. S., Lurz, P., Munzel, T., Daiber, A. & Jansen, T. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39351780
Ten-year clinical outcomes after drug-eluting stents implantation according to clinical presentation-Insights from the DECADE cooperation. Starnecker, F., Coughlan, J. J., Jensen, L. O., Bar, S., Kufner, S., Brugaletta, S., Raber, L., Maeng, M., Ortega-Paz, L., Heg, D., Laugwitz, K. L., Sabate, M., Windecker, S., Kastrati, A., Olesen, K. K. W. & Cassese, S. Eur J Clin Invest, e14323 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39351821
Predictors of symptom improvement in patients with chronic coronary syndrome after percutaneous coronary intervention. Wester, M., Koll, F., Luedde, M., Langer, C., Resch, M., Luchner, A., Muller, K., Zeman, F., Koller, M., Maier, L. S. & Sossalla, S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39352518
Multicentre, randomized, double-blind, prospective study on the effects of ImmunoAdSorptiOn on cardiac function in patients with Dilated CardioMyopathy (IASO-DCM): Rationale and design. Dorr, M., Bohm, M., Erdmann, E., Gross, S., Mahabadi, A. A., Nauck, M., Nickening, G., Schultheiss, H. P., Staudt, A., Werdan, K., Waagstein, F., Hjalmarson, A. & Felix, S. B. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39359033
Disentangling Anemia in Frailty: Exploring the role of Inflammation. Herpich, C., Goger, L., Faust, L., Kalymon, M., Ott, C., Walter, S., Lehmkuhl, E., Grune, T., Moskiou, V., Muller-Werdan, U. & Norman, K. J Gerontol A Biol Sci Med Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/39360829
Deep-Learning-Based Disease Classification in Patients Undergoing Cine Cardiac MRI. Jacob, A. J., Chitiboi, T., Schoepf, U. J., Sharma, P., Aldinger, J., Baker, C., Lautenschlager, C., Emrich, T. & Varga-Szemes, A. J Magn Reson Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/39353848
European Association of Cardiothoracic Surgeons future view on robotic cardiac surgery in Europe. Oosterlinck, W., Gianoli, M., Palmen, M., Folliguet, T., Bonatti, J., Agnino, A., Singh, S., Franke, U., Modi, P., Pereda, D., Kempfert, J., Navarra, E., Suwalski, P., Vojacek, J., Casselman, F., Myers, P., Sadaba, J. R., Melfi, F., Hazekamp, M., Bavaria, J., Beyersdorf, F., Milojevics, M., Falk, V. & Cerny, S. Eur J Cardiothorac Surg 66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39353655
Underreporting of complications following AF ablation: Comparison of the manufacturer and user facility device experience FDA database and a voluntary invitation-based registry: The POTTER-AF 3 study. Tilz, R. R., Purerfellner, H., Kuck, K. H., Merino, J. L., Schmidt, V., Vogler, J., Xiang, K., Uzunoglu, E. C., Heeger, C. H., Tandri, H., Assis, F., Steven, D., Veltmann, C., Catanzaro, J. N. & Popescu, S. S. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/39353499
Establishing the TSH reference intervals for healthy adults aged over 70 years: the Australian ASPREE cohort study. Tran, C., Topliss, D. J., Schneider, H. G., Seeman, E., Clayton-Chubb, D., Neumann, J. T., Kakoly, N., Zhou, Z., Hussain, S. M., Rickard, A. J., Clark, D. P. Q., Shah, R. C., Woods, R. L. & McNeil, J. J. Clin Chem Lab Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39358350
SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor. Alnouri, M. W., Roquid, K. A., Bonnavion, R., Cho, H., Heering, J., Kwon, J., Jager, Y., Wang, S., Gunther, S., Wettschureck, N., Geisslinger, G., Gurke, R., Muller, C. E., Proschak, E. & Offermanns, S. Proc Natl Acad Sci U S A 121, e2407130121 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39365815
Acute alcohol consumption and arrhythmias in young adults: the MunichBREW II study. Brunner, S., Krewitz, C., Winter, R., von Falkenhausen, A. S., Kern, A., Brunner, D. & Sinner, M. F. Eur Heart J 45, 4938-4949 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39363568
4D-Flow MRI and Vector Ultrasound in the In-Vitro Evaluation of Surgical Aortic Heart Valves - a Pilot Study. Stephan, H., Grefen, L., Clevert, D., Onkes, M., Ning, J., Thierfelder, N., Mela, P., Hagl, C., Curta, A. & Grab, M. J Cardiovasc Transl Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39365396
Association between Long-Term Exposure to Traffic-Related Air Pollution and Cardio-Metabolic Phenotypes: An MRI Data-Based Analysis. Woeckel, M., Rospleszcz, S., Wolf, K., Breitner-Busch, S., Ingrisch, M., Bamberg, F., Ricke, J., Schlett, C. L., Storz, C., Schneider, A., Stoecklein, S. & Peters, A. Environ Sci Technol 58, 18064-18075 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39365792
Baseline Platelet Count Predicts Infarct Size and Mortality after Acute Myocardial Infarction. Dutsch, A., Graesser, C., Novacek, S., Krefting, J., Schories, V., Niedermeier, B., Voll, F., Kufner, S., Xhepa, E., Joner, M., Cassese, S., Schunkert, H., Ndrepepa, G., Kastrati, A., Kessler, T. & Sager, H. B. Hamostaseologie (2024). https://www.ncbi.nlm.nih.gov/pubmed/39366427
Cardiovascular Events After Chimeric Antigen Receptor T-Cell Therapy for Advanced Hematologic Malignant Neoplasms: A Meta-Analysis. Koeckerling, D., Reddy, R. K., Barker, J., Eichhorn, C., Divall, P., Howard, J. P., Korell, F., Schmitt, M., Dreger, P., Frey, N. & Lehmann, L. H. JAMA Netw Open 7, e2437222 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39374017
Is myocardial accumulation of non-transferrin-bound iron clinically relevant? von Haehling, S., Sato, R. & Anker, S. D. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39374343
Non-Hotspot PIK3CA Variants Have Higher Variant Allele Frequency and are More Common in Syndromic Vascular Malformations. Andreoti, T. A., Maiolo, M., Tuleja, A., Doring, Y., Schaller, A., Vassella, E., Boon, L. M., Baumgartner, I., Bernhard, S. M., Zweier, C., Vikkula, M. & Rossler, J. Am J Med Genet A, e63883 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39376044
Real-world experience in initiation of treatment with the selective cardiomyosin inhibitor mavacamten in an outpatient clinic cohort during the 12-week titration period. Becker, F., Novotny, J., Jansen, N., Clauss, S., Moller-Dyrna, F., Specht, B., Orban, M., Massberg, S., Kaab, S. & Reichart, D. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39377920
TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia. Broker-Lai, J., Rego Terol, J., Richter, C., Mathar, I., Wirth, A., Kopf, S., Moreno-Perez, A., Buttner, M., Tan, L. L., Makke, M., Poschet, G., Hermann, J., Tsvilovskyy, V., Haberkorn, U., Wartenberg, P., Susperreguy, S., Berlin, M., Ottenheijm, R., Philippaert, K., Wu, M., Wiedemann, T., Herzig, S., Belkacemi, A., Levinson, R. T., Agarwal, N., Camacho Londono, J. E., Klebl, B., Dinkel, K., Zufall, F., Nussbaumer, P., Boehm, U., Hell, R., Nawroth, P., Birnbaumer, L., Leinders-Zufall, T., Kuner, R., Zorn, M., Bruns, D., Schwarz, Y. & Freichel, M. EMBO J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39375537
Cardiac arrhythmias: the growing role of autoantibodies in diagnosis and treatment. Fakuade, F. E., Grune, J. & Voigt, N. Eur Heart J 45, 4349-4351 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39378151
Correction: Follicular reconstruction and neo-oogenesis in xenotransplantation of human ovarian isolated cells derived from chemotherapy-induced POF patients. Khaleghi, S., Eivazkhani, F., Tavana, S., Moini, A., Novin, M. G., Stoyan, P., Nazarian, H. & Fathi, R. J Biol Eng 18, 55 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39375722
Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow. Lim, X. R., Abd-Alhaseeb, M. M., Ippolito, M., Koide, M., Senatore, A. J., Plante, C., Hariharan, A., Weir, N., Longden, T. A., Laprade, K. A., Stafford, J. M., Ziemens, D., Schwaninger, M., Wenzel, J., Postnov, D. D. & Harraz, O. F. Nat Commun 15, 8686 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39375369
Inflammation in liver fibrosis and atrial fibrillation: A prospective population-based proteomic study. Boeckmans, J., Michel, M., Gieswinkel, A., Tuscher, O., Konstantinides, S. V., Konig, J., Munzel, T., Lackner, K. J., Kerahrodi, J. G., Schuster, A. K., Wild, P. S., Galle, P. R. & Schattenberg, J. M. JHEP Rep 6, 101171 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39380717
Macrophages enhance sodium channel expression in cardiomyocytes. Bogert, N. V., Therre, M., Din, S., Furkel, J., Zhou, X., El-Battrawy, I., Heineke, J., Schweizer, P. A., Akin, I., Katus, H. A., Frey, N., Leuschner, F. & Konstandin, M. H. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39382673
Insulin oxidation and oxidative modifications alter glucose uptake, cell metabolism, and inflammatory secretion profiles. Clemen, R., Dethloff, W., Berner, J., Schulan, P., Martinet, A., Weltmann, K. D., von Woedtke, T., Grune, T., Wende, K. & Bekeschus, S. Redox Biol77, 103372 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39378614
Hypokalaemia in patients with type 2 diabetes and chronic kidney disease: the effect of finerenone - a FIDELITY analysis. Pitt, B., Agarwal, R., Anker, S. D., Rossing, P., Ruilope, L., Herzog, C. A., Greenberg, B., Pecoits-Filho, R., Lambelet, M., Lawatscheck, R., Scalise, A. & Filippatos, G. Eur Heart J Cardiovasc Pharmacother (2024). https://www.ncbi.nlm.nih.gov/pubmed/39380152
Interleukin 11 therapy causes acute left ventricular dysfunction. Sweeney, M., O'Fee, K., Villanueva-Hayes, C., Rahman, E., Lee, M., Tam, C. N., Pascual-Navarro, E., Maatz, H., Lindberg, E. L., Vanezis, K., Ramachandra, C. J., Andrew, I., Jennings, E. R., Lim, W. W., Widjaja, A. A., Carling, D., Hausenloy, D. J., Hubner, N., Barton, P. J. R. & Cook, S. A. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39383190
2024 EACTS Guidelines on perioperative medication in adult cardiac surgery. Jeppsson, A., Rocca, B., Hansson, E. C., Gudbjartsson, T., James, S., Kaski, J. K., Landmesser, U., Landoni, G., Magro, P., Pan, E., Ravn, H. B., Sandner, S., Sandoval, E., Uva, M. S., Milojevic, M. & Group, E. S. D. Eur J Cardiothorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39385505
Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis. Ofoghi, A., Kotschi, S., Lemmer, I. L., Haas, D. T., Willemsen, N., Bayer, B., Jung, A. S., Moller, S., Haberecht-Muller, S., Kruger, E., Krahmer, N. & Bartelt, A. Cell Death Differ (2024). https://www.ncbi.nlm.nih.gov/pubmed/39384955
Gut microbiota-related modulation of immune mechanisms in post-infarction remodelling and heart failure. Roessler, J., Zimmermann, F., Heidecker, B., Landmesser, U. & Haghikia, A. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39385474
Corrigendum to "Detection and analysis of cerebral aneurysms based on X-ray rotational angiography - the CADA 2020 challenge" [Medical Image Analysis, April 2022, Volume 77, 102333]. Ivantsits, M., Goubergrits, L., Kuhnigk, J. M., Huellebrand, M., Bruening, J., Kossen, T., Pfahringer, B., Schaller, J., Spuler, A., Kuehne, T., Jia, Y., Li, X., Shit, S., Menze, B., Su, Z., Ma, J., Nie, Z., Jain, K., Liu, Y., Lin, Y. & Hennemuth, A. Med Image Anal, 103363 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39389883
[Cardiovascular prevention in Saxony-Anhalt : Necessity and new perspectives]. Muller, P., Herzog, M., Duderstadt, Y., Kunz, M., Lechner, K., Meyer, F., Schmeisser, A., Meissler, S., Ahrens, D., Neumann, K., Mattern, H., Speck, O., Behme, D., Dunay, I. R., Seeland, U., Schreiber, S. & Braun-Dullaeus, R. Inn Med (Heidelb) (2024). https://www.ncbi.nlm.nih.gov/pubmed/39387861
Reduction of Cardiac Allograft Vasculopathy by PCI: Quantification and Correlation With Outcome After Heart Transplantation. Orban, M., Kuehl, A., Pechmajou, L., Muller, C., Sfeir, M., Brunner, S., Braun, D., Hausleiter, J., Bories, M. C., Martin, A. C., Ulrich, S., Dalla Pozza, R., Mehilli, J., Jouven, X., Hagl, C., Karam, N. & Massberg, S. J Card Fail 30, 1222-1230 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39389730
Assessment of psychological resilience in a large cohort of the general population: Validation and norm values of the RS-5. Reinwarth, A. C., Hahad, O., Ghaemi Kerahrodi, J., Brahler, E., Lieb, K., Gilan, D., Zahn, D., Chalabi, J., Schuster, A. K., Schepers, M., Lackner, K. J., Schattenberg, J. M., Ruf, W., Wild, P. S., Daiber, A., Michal, M., Beutel, M. E. & Munzel, T. PLoS One19, e0309197 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39392830
Right Ventricular Dysfunction in Patients Undergoing High-Risk PCI with Impella. Rommel, K. P., Bonnet, G., Bellumkonda, L., Lansky, A. J., Zhao, D., Thompson, J. B., Zhang, Y., Redfors, B., Lurz, P. C., Granada, J. F., Bharadwaj, A. S., Basir, M. B., O'Neill, W. W. & Burkhoff, D. J Card Fail 30, 1244-1254 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39389734
Automatic structuring of radiology reports with on-premise open-source large language models. Woznicki, P., Laqua, C., Fiku, I., Hekalo, A., Truhn, D., Engelhardt, S., Kather, J., Foersch, S., D'Antonoli, T. A., Pinto Dos Santos, D., Baessler, B. & Laqua, F. C. Eur Radiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39390261
Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures. Lenarczyk, R., Proietti, M., Scheitz, J. F., Shah, D., Siebert, E., Gorog, D. A., Kowalczyk, J., Bonaros, N., Ntaios, G., Doehner, W., Van Mieghem, N. M., Nardai, S., Kovac, J., Fiszer, R., Lorusso, R., Navarese, E., Castrejon, S., Rubboli, A., Rivera-Caravaca, J. M., Chieffo, A. & Lip, G. Y. H. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39394524
Periodontitis adversely affects lipoprotein subfractions - results from the cohort study SHIP-TREND: Periodontitis adversely affects lipoprotein subfractions. Basdorf, P., Kocher, T., Baumeister, S. E., Pink, C., Budde, K., Petersmann, A., Friedrich, N., Volzke, H., Nauck, M. & Holtfreter, B. Diabetes Metab 50, 101584 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39396553
Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy. Gao, Z., Dremova, O., Karwot, C., Reinhardt, C. & Kiouptsi, K. J Vis Exp (2024). https://www.ncbi.nlm.nih.gov/pubmed/39400168
Accelerated calciprotein crystallization time (T50) is correlated with impaired lung diffusion capacity in systemic sclerosis. Geroldinger-Simic, M., Sohail, A., Razazian, M., Krennmayr, B., Pernsteiner, V., Putz, T., Lackner, H. K., Pasch, A., Sepp, N., Alesutan, I. & Voelkl, J. Front Immunol 15, 1425885 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39399492
Nutritional strategies for improving sarcopenia outcomes in older adults: A narrative review. Goes-Santos, B. R., Carson, B. P., da Fonseca, G. W. P. & von Haehling, S. Pharmacol Res Perspect 12, e70019 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39400516
A regulatory loop involving the cytochrome P450-soluble epoxide hydrolase axis and TGF-beta signaling. Li, X., Kempf, S., Delgado Lagos, F., Ukan, U., Popp, R., Hu, J., Fromel, T., Gunther, S., Weigert, A. & Fleming, I. iScience 27, 110938 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39398242
A breath of fresh air: targeted non-viral in vivo gene correction in the mammalian lung. Liu, J. & Grimm, D. Signal Transduct Target Ther 9, 286 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39397026
Occlusion of functional high-volume intra-atrial shunts in older patients after embolic stroke of undetermined source. Schrader, H., Boldt, L. H., Parwani, A. S., Blaschke, F., Wiedenhofer, J. M., Trippel, T. D., Hindricks, G., Starck, C., Dreger, H., Sherif, M. & Primessnig, U. Front Cardiovasc Med 11, 1402137 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39399510
Cardiac troponin elevation and mortality in takotsubo syndrome: New insights from the international takotsubo registry. Stahli, B. E., Schindler, M., Schweiger, V., Cammann, V. L., Szawan, K. A., Niederseer, D., Wurdinger, M., Schonberger, A., Schonberger, M., Koleva, I., Mercier, J. C., Petkova, V., Mayer, S., Citro, R., Vecchione, C., Bossone, E., Gili, S., Neuhaus, M., Franke, J., Meder, B., Jaguszewski, M., Noutsias, M., Knorr, M., Jansen, T., D'Ascenzo, F., Dichtl, W., von Lewinski, D., Burgdorf, C., Kherad, B., Tschope, C., Sarcon, A., Shinbane, J., Rajan, L., Michels, G., Pfister, R., Cuneo, A., Jacobshagen, C., Karakas, M., Koenig, W., Pott, A., Meyer, P., Roffi, M., Banning, A., Wolfrum, M., Cuculi, F., Kobza, R., Fischer, T. A., Vasankari, T., Airaksinen, K. E. J., Napp, L. C., Dworakowski, R., MacCarthy, P., Kaiser, C., Osswald, S., Galiuto, L., Chan, C., Bridgman, P., Beug, D., Delmas, C., Lairez, O., Gilyarova, E., Shilova, A., Gilyarov, M., El-Battrawy, I., Akin, I., Polednikova, K., Tousek, P., Winchester, D. E., Massoomi, M., Galuszka, J., Ukena, C., Poglajen, G., Carrilho-Ferreira, P., Hauck, C., Paolini, C., Bilato, C., Kobayashi, Y., Kato, K., Ishibashi, I., Himi, T., Din, J., Al-Shammari, A., Prasad, A., Rihal, C. S., Liu, K., Schulze, P. C., Bianco, M., Jorg, L., Rickli, H., Pestana, G., Nguyen, T. H., Bohm, M., Maier, L. S., Pinto, F. J., Widimsky, P., Felix, S. B., Braun-Dullaeus, R. C., Rottbauer, W., Hasenfuss, G., Pieske, B. M., Schunkert, H., Budnik, M., Opolski, G., Thiele, H., Bauersachs, J., Horowitz, J. D., Di Mario, C., Kong, W., Dalakoti, M., Imori, Y., Liberale, L., Montecucco, F., Munzel, T., Crea, F., Luscher, T. F., Bax, J. J., Ruschitzka, F., Ghadri, J. R., Di Vece, D. & Templin, C. Eur J Clin Invest, e14317 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39397275
The influence of post-processing software on quantitative results in 4D flow cardiovascular magnetic resonance examinations. Trauzeddel, R. F., Muller, M., Demir, A., Wiesemann, S., Daud, E., Schmitter, S., Viezzer, D., Hadler, T. & Schulz-Menger, J. Front Cardiovasc Med 11, 1465554 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39399512
Seroprevalence of binding and neutralizing antibodies against 18 adeno-associated virus types in patients with neuromuscular disorders. Wang, X., Klann, P. J., Wiedtke, E., Sano, Y., Fischer, N., Schiller, L., Elfert, A., Guttsches, A. K., Weyen, U., Grimm, D., Vorgerd, M. & Bayer, W. Front Immunol 15, 1450858 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39399494
Thermomechanical properties of bat and human red blood cells-Implications for hibernation. Fregin, B., Hossain, M. F., Biedenweg, D., Friedrichs, V., Balkema-Buschmann, A., Bokelmann, M., Lehnert, K., Mokbel, D., Aland, S., Scholz, C. C., Lehmann, P., Otto, O. & Kerth, G. Proc Natl Acad Sci U S A 121, e2405169121 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39401351
muCT imaging of a multi-organ vascular fingerprint in rats. Napieczynska, H., Kedziora, S. M., Haase, N., Muller, D. N., Heuser, A., Dechend, R. & Kraker, K. PLoS One19, e0308601 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39401231
Chemotherapy-induced cognitive impairment and its long-term development in patients with breast cancer: results from the observational CICARO study. Kerkmann, A., Schinke, C., Dordevic, A., Kern, J., Bangemann, N., Finck, J., Blohmer, J. U., Ruprecht, K., Gopfert, J. C., Otto, C., Materne, B., Endres, M., Boehmerle, W. & Huehnchen, P. Oncologist (2024). https://www.ncbi.nlm.nih.gov/pubmed/39403794
A validated heart-specific model for splice-disrupting variants in childhood heart disease. Lesurf, R., Breckpot, J., Bouwmeester, J., Hanafi, N., Jain, A., Liang, Y., Papaz, T., Lougheed, J., Mondal, T., Alsalehi, M., Altamirano-Diaz, L., Oechslin, E., Audain, E., Dombrowsky, G., Postma, A. V., Woudstra, O. I., Bouma, B. J., Hitz, M. P., Bezzina, C. R., Blue, G. M., Winlaw, D. S. & Mital, S. Genome Med16, 119 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39402625
Oxidative stress initiates hemodynamic change in CKD-induced heart disease. Sen, P., Hamers, J., Sittig, T., Shashikadze, B., d'Ambrosio, L., Stockl, J. B., Bierschenk, S., Zhang, H., d'Alessio, C., Zandbergen, L. M., Pauly, V., Clauss, S., Wolf, E., Dendorfer, A., Frohlich, T. & Merkus, D. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39404904
Randomized Trial of COBRA PzF Stenting to Reduce the Duration of Triple Therapy: The COBRA-REDUCE Trial. Byrne, R. A., Colleran, R., Coughlan, J. J., Jauhar, R., Maillard, L., De Labriolle, A., Maeng, M., Croft, C., Brunner, M., Leistner, D., Zrenner, B., Kollum, M., Laugwitz, K. L., Xhepa, E., Mayer, K., Lahu, S., Joner, M., Kirtane, A., Mehran, R., Barakat, M., Urban, P., Cutlip, D. E., Kastrati, A. & Investigators, C.-R. Circ Cardiovasc Interv 17, e013735 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39405373
Addressing SARS-CoV-2 viroporins with antiarrhythmic drugs. Bloothooft, M., Voigt, N. & de Boer, T. P. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39412365
ESC/EACTS guideline for chronic coronary syndrome-invasive treatment perspectives important for daily practice. Doenst, T., Borger, M., Falk, V. & Milojevic, M. Eur J Cardiothorac Surg66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39406390
Automated segment-level coronary artery calcium scoring on non-contrast CT: a multi-task deep-learning approach. Follmer, B., Tsogias, S., Biavati, F., Schulze, K., Bosserdt, M., Hovermann, L. G., Stober, S., Samek, W., Kofoed, K. F., Maurovich-Horvat, P., Donnelly, P., Benedek, T., Williams, M. C. & Dewey, M. Insights Imaging 15, 250 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39412613
Propensity score-based comparison of high-risk coronary artery bypass grafting vs. left ventricular assist device implantation in patients with coronary artery disease and advanced heart failure. Nersesian, G., Abd El Al, A., Schoenrath, F., Zittermann, A., Hell, L., Falk, V., de By, T., Fox, H., Schramm, R., Morshuis, M., Gummert, J., Potapov, E. & Rojas, S. V. Front Cardiovasc Med 11, 1430560 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39411171
Aortic and Mitral Valve Endocarditis-Simply Left-Sided Endocarditis or Different Entities Requiring Individual Consideration?-Insights from the CAMPAIGN Database. Weber, C., Marin-Cuartas, M., Tugtekin, S. M., Diab, M., Saha, S., Akhyari, P., Elderia, A., Muench, F., Petrov, A., Aubin, H., Misfeld, M., Lichtenberg, A., Hagl, C., Doenst, T., Matschke, K., Borger, M. A., Wahlers, T., Luehr, M. & Study Group "Clinical, M. P. o. A. o. I. E. i. G. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39407901
A Prospective, Randomized Trial of Bioresorbable Polymer Drug-Eluting Stents versus Fully Bioresorbable Scaffolds in Patients Undergoing Coronary Stenting. Wiebe, J., Byrne, R. A., Bradaric, C., Kuna, C., Kessler, T., Pfleiderer, M., Kufner, S., Xhepa, E., Hoppmann, P., Joner, M., Schunkert, H., Laugwitz, K. L., Kastrati, A. & Cassese, S. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39408009
SARS-CoV-2 ORF 3a-mediated currents are inhibited by antiarrhythmic drugs. Wiedmann, F., Boondej, E., Stanifer, M., Paasche, A., Kraft, M., Pruser, M., Seeger, T., Uhrig, U., Boulant, S. & Schmidt, C. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39412366
Transient High Salt Intake Promotes T-Cell-Mediated Hypertensive Vascular Injury. Yakoub, M., Rahman, M., Kleimann, P., Hoffe, J., Feige, M., Bouvain, P., Alter, C., Kluczny, J. I., Reidel, S., Nederlof, R., Hering, L., Argov, D., Arifaj, D., Kantauskaite, M., Meister, J., Kleinewietfeld, M., Rump, L. C., Jantsch, J., Flogel, U., Muller, D. N., Temme, S. & Stegbauer, J. Hypertension (2024). https://www.ncbi.nlm.nih.gov/pubmed/39411864
Through the patients' eyes: psychometric evaluation of the 64-item version of the Experienced Patient-Centeredness Questionnaire (EPAT-64). Christalle, E., Zeh, S., Fuhres, H., Schellhorn, A., Hahlweg, P., Zill, J. M., Harter, M., Bokemeyer, C., Gallinat, J., Gebhardt, C., Magnussen, C., Muller, V., Schmalstieg-Bahr, K., Strahl, A., Kriston, L. & Scholl, I. BMJ Qual Saf (2024). https://www.ncbi.nlm.nih.gov/pubmed/39414377
Risk factors and clinical significance of post-stroke incident ischemic lesions. Fang, R., Duering, M., Bode, F. J., Stosser, S., Meissner, J. N., Hermann, P., Liman, T. G., Nolte, C. H., Kerti, L., Ikenberg, B., Bernkopf, K., Glanz, W., Janowitz, D., Wagner, M., Neumann, K., Speck, O., Duzel, E., Gesierich, B., Dewenter, A., Spottke, A., Waegemann, K., Gortler, M., Wunderlich, S., Zerr, I., Petzold, G. C., Endres, M., Georgakis, M. K., Dichgans, M. & investigators, D. Alzheimers Dement (2024). https://www.ncbi.nlm.nih.gov/pubmed/39417418
Prognostic Impact of Admission Time in Infarct-Related Cardiogenic Shock: An ECLS-SHOCK Substudy. Schupp, T., Thiele, H., Rassaf, T., Abbas Mahabadi, A., Lehmann, R., Eitel, I., Skurk, C., Clemmensen, P., Hennersdorf, M., Voigt, I., Linke, A., Tigges, E., Nordbeck, P., Jung, C., Lauten, P., Feistritzer, H. J., Poss, J., Ouarrak, T., Schneider, S., Behnes, M., Duerschmied, D., Desch, S., Freund, A., Zeymer, U. & Akin, I. JACC Cardiovasc Interv 17, 2228-2239 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39415381
Normal male fertility in a mouse model of KPNA2 deficiency. Rother, F., Abu Hweidi, D., Hartmann, E. & Bader, M. PLoS One 19, e0304189 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39423201
Site-specific m6A-miR-494-3p, not unmethylated miR-494-3p, compromises blood brain barrier by targeting tight junction protein 1 in intracranial atherosclerosis. Woudenberg, T., van der Bent, M. L., Kremer, V., Waas, I. S. E., Daemen, M., Boon, R. A., Quax, P. H. A. & Nossent, A. Y. Br J Pharmacol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39419283
Computed tomography for the detection of myocardial hypoperfusion in acute myocardial infarction and the associated CT-to-catheter time. Mostafa, K., Seoudy, H., Aludin, S., Schunk, D., Peckolt, H., Wolf, C., Saad, M., Both, M., Jansen, O., Frank, D. & Langguth, P. Sci Rep 14, 24456 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39424899
Left Ventricular Ejection Fraction Change Following Percutaneous Coronary Intervention: Correlates and Association With Prognosis. Ndrepepa, G., Cassese, S., Byrne, R. A., Bevapi, B., Joner, M., Sager, H. B., Kufner, S., Xhepa, E., Ibrahim, T., Laugwitz, K. L., Schunkert, H. & Kastrati, A. J Am Heart Assoc, e035791 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39424424
Design and Rationale of a Pragmatic Randomized Clinical Trial of Early Dronedarone versus Usual Care to Change and Improve Outcomes in Persons with First-Detected Atrial Fibrillation - The CHANGE AFIB Study. Pokorney, S. D., Nemeth, H., Chiswell, K., Albert, C., Allyn, N., Blanco, R., Butler, J., Calkins, H., Elkind, M. S. V., Fonarow, G. C., Fontaine, J. M., Frankel, D. S., Fermann, G. J., Gale, R., Kalscheur, M., Kirchhof, P., Koren, A., Miller, J. B., Rashkin, J., Russo, A. M., Rutan, C., Steinberg, B. & Piccini, J. P. Am Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39423993
NoxO1 regulates EGFR signaling by its interaction with Erbin. Hebchen, D. M., Schader, T., Spaeth, M., Muller, N., Graumann, J. & Schroder, K. Redox Biol 77, 103396 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39426288
Targeting Sphingosine-1-Phosphate Signaling to Prevent the Progression of Aortic Valve Disease. Benkhoff, M., Barcik, M., Mourikis, P., Dahlmanns, J., Kahmann, P., Wollnitzke, P., Hering, M., Huckenbeck, T., Hoppe, J., Semleit, N., Deister-Jonas, J., Zako, S., Seel, J., Coman, C., Barth, M., Cramer, M., Helten, C., Wildeis, L., Hu, H., Al-Kassis, G., Metzen, D., Hesse, J., Weber, J., Dannenberg, L., Akhyari, P., Lichtenberg, A., Quast, C., Gerdes, N., Zeus, T., Borst, O., Kelm, M., Petzold, T., Ahrends, R., Levkau, B. & Polzin, A. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39429140
Mitral valve edge-to-edge repair under scrutiny: what can we learn from transoesophageal echocardiographic follow-up? Hausleiter, J. & Stolz, L. EuroIntervention 20, e1262-e1263 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39432257
Sarcopenia influences clinical outcome in hospitalized patients with peripheral artery disease aged 75 years and older. Schmitt, V. H., Hobohm, L., Brochhausen, C., Espinola-Klein, C., Lurz, P., Munzel, T., Hahad, O. & Keller, K. Ann Vasc Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39427977
Gpr55 deficiency crucially alters cardiomyocyte homeostasis and counteracts angiotensin II induced maladaption in female mice. Schopohl, B., Kohlhaas, M., Nickel, A. G., Schiuma, A. F., Maas, S. L., van der Vorst, E. P. C., Shia, Y. X., Maack, C., Steffens, S. & Puhl, S. L. Br J Pharmacol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39428581
Specific calcium deposition on pre-procedural CCTA at the time of percutaneous coronary intervention predicts in-stent restenosis in symptomatic patients. Adolf, R., Krinke, I., Datz, J., Cassese, S., Kastrati, A., Joner, M., Schunkert, H., Wall, W., Hadamitzky, M. & Engel, L. C. J Cardiovasc Comput Tomogr (2024). https://www.ncbi.nlm.nih.gov/pubmed/39433461
Pharmacological management of heart failure: a patient-centered approach. Fibbi, G., Sato, R., Vatic, M., Genreith, F. P. & von Haehling, S. Expert Opin Pharmacother (2024). https://www.ncbi.nlm.nih.gov/pubmed/39434709
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries. Garcia-Marin, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., Grasby, K. L., Thorp, J. G., Agartz, I., Alhusaini, S., Ames, D., Amouyel, P., Andreassen, O. A., Arfanakis, K., Arias-Vasquez, A., Armstrong, N. J., Athanasiu, L., Bastin, M. E., Beiser, A. S., Bennett, D. A., Bis, J. C., Boks, M. P. M., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Buitelaar, J. K., Burkhardt, R., Cahn, W., Calhoun, V. D., Carmichael, O. T., Chakravarty, M., Chen, Q., Ching, C. R. K., Cichon, S., Crespo-Facorro, B., Crivello, F., Dale, A. M., Smith, G. D., de Geus, E. J. C., De Jager, P. L., de Zubicaray, G. I., Debette, S., DeCarli, C., Depondt, C., Desrivieres, S., Djurovic, S., Ehrlich, S., Erk, S., Espeseth, T., Fernandez, G., Filippi, I., Fisher, S. E., Fleischman, D. A., Fletcher, E., Fornage, M., Forstner, A. J., Francks, C., Franke, B., Ge, T., Goldman, A. L., Grabe, H. J., Green, R. C., Grimm, O., Groenewold, N. A., Gruber, O., Gudnason, V., Haberg, A. K., Haukvik, U. K., Heinz, A., Hibar, D. P., Hilal, S., Himali, J. J., Ho, B. C., Hoehn, D. F., Hoekstra, P. J., Hofer, E., Hoffmann, W., Holmes, A. J., Homuth, G., Hosten, N., Ikram, M. K., Ipser, J. C., Jack, C. R., Jr., Jahanshad, N., Jonsson, E. G., Kahn, R. S., Kanai, R., Klein, M., Knol, M. J., Launer, L. J., Lawrie, S. M., Hellard, S. L., Lee, P. H., Lemaitre, H., Li, S., Liewald, D. C. M., Lin, H., Longstreth, W. T., Jr., Lopez, O. L., Luciano, M., Maillard, P., Marquand, A. F., Martin, N. G., Martinot, J. L., Mather, K. A., Mattay, V. S., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mirza-Schreiber, N., Milaneschi, Y., Mosley, T. H., Muhleisen, T. W., Muller-Myhsok, B., Maniega, S. M., Nauck, M., Nho, K., Niessen, W. J., Nothen, M. M., Nyquist, P. A., Oosterlaan, J., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B., Pike, G. B., Psaty, B. M., Putz, B., Reppermund, S., Rietschel, M. D., Risacher, S. L., Romanczuk-Seiferth, N., Romero-Garcia, R., Roshchupkin, G. V., Rotter, J. I., Sachdev, P. S., Samann, P. G., Saremi, A., Sargurupremraj, M., Saykin, A. J., Schmaal, L., Schmidt, H., Schmidt, R., Schofield, P. R., Scholz, M., Schumann, G., Schwarz, E., Shen, L., Shin, J., Sisodiya, S. M., Smith, A. V., Smoller, J. W., Soininen, H. S., Steen, V. M., Stein, D. J., Stein, J. L., Thomopoulos, S. I., Toga, A. W., Tordesillas-Gutierrez, D., Trollor, J. N., Valdes-Hernandez, M. C., van, T. E. D., van Bokhoven, H., van der Meer, D., van der Wee, N. J. A., Vazquez-Bourgon, J., Veltman, D. J., Vernooij, M. W., Villringer, A., Vinke, L. N., Volzke, H., Walter, H., Wardlaw, J. M., Weinberger, D. R., Weiner, M. W., Wen, W., Westlye, L. T., Westman, E., White, T., Witte, A. V., Wolf, C., Yang, J., Zwiers, M. P., Ikram, M. A., Seshadri, S., Thompson, P. M., Satizabal, C. L., Medland, S. E. & Renteria, M. E. Nat Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/39433889
Hypoxia sensing in resident cardiac macrophages regulates monocyte fate specification following ischemic heart injury. Kadyrov, F. F., Koenig, A. L., Amrute, J. M., Dun, H., Li, W., Weinheimer, C. J., Nigro, J. M., Kovacs, A., Bredemeyer, A. L., Yang, S., Das, S., Penna, V. R., Parvathaneni, A., Lai, L., Hartmann, N., Kopecky, B. J., Kreisel, D. & Lavine, K. J. Nat Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39433910
Mapping lineage-traced cells across time points with moslin. Lange, M., Piran, Z., Klein, M., Spanjaard, B., Klein, D., Junker, J. P., Theis, F. J. & Nitzan, M. Genome Biol 25, 277 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39434128
Procoagulant platelet activation promotes venous thrombosis. Kaiser, R., Dewender, R., Mulkers, M., Stermann, J., Rossaro, D., Di Fina, L., Li, L., Gold, C., Schmid, M., Kaab, L., Eivers, L., Akgol, S., Yue, K., Kammerer, L., Loew, Q., Anjum, A., Escaig, R., Akhalkatsi, A., Laun, L., Kranich, J., Brocker, T., Mueller, T. T., Krachan, A., Gmeiner, J., Pekayvaz, K., Thienel, M., Massberg, S., Stark, K., Kilani, B. & Nicolai, L. Blood 144, 2546-2553 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39440970
Senescent Syncytiotrophoblast Secretion During Early Onset Preeclampsia. Nonn, O., Debnath, O., Valdes, D. S., Sallinger, K., Secener, A. K., Fischer, C., Tiesmeyer, S., Nimo, J., Kuenzer, T., Ulrich, J., Maxian, T., Knofler, M., Karau, P., Bartolomaeus, H., Kroneis, T., Frolova, A., Neuper, L., Haase, N., Malt, A., Muller-Botticher, N., Kraker, K., Kedziora, S., Forstner, D., Eils, R., Schmidt-Ullrich, R., Haider, S., Verlohren, S., Stern, C., Sugulle, M., Jones, S., Thilaganathan, B., Kaitu'u-Lino, T. J., Tong, S., Huppertz, B., El-Heliebi, A., Staff, A. C., Coscia, F., Muller, D. N., Dechend, R., Gauster, M., Ishaque, N. & Herse, F. Hypertension (2024). https://www.ncbi.nlm.nih.gov/pubmed/39440423
Effects of atrial fibrillation ablation on arrhythmia burden and ventricular function in end-stage heart failure: Lessons from CASTLE-HTx. Sciacca, V., Sohns, C., Crijns, H., Marrouche, N. F., Schramm, R., Moersdorf, M., Fink, T., Bergau, L., Hindricks, G., Dagres, N., Sossalla, S., Costard-Jaeckle, A., Fox, H., El Hamriti, M., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., Sommer, P. & Investigators, C. H. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39444312
New-generation single-layer PTFE-covered coronary stent for endovascular repair of iatrogenic arterial side-branch injury in non-coronary lesions for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators. Strauss, L., Gibello, L., Voll, F., Alvarez-Covarrubias, H. A., Lenz, T., Cassese, S., Xhepa, E., Joner, M., Schunkert, H., Kastrati, A., Ruffino, M. A. & Kufner, S. Cardiovasc Revasc Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39443255
Timing of veno-arterial extracorporeal membrane oxygenation support in patients with cardiogenic shock. Sundermeyer, J., Kellner, C., Beer, B. N., Dettling, A., Besch, L., Blankenberg, S., Eitel, I., Frank, D., Frey, N., Graf, T., Kirchhof, P., Krais, J., von Lewinski, D., Mangner, N., Mobius-Winkler, S., Nordbeck, P., Orban, M., Pauschinger, M., Sag, C. M., Scherer, C., Skurk, C., Thiele, H., Westermann, D. & Schrage, B. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39444297
High chloride induces aldosterone resistance in the distal nephron. Vitzthum, H., Hauswald, N., Pham, H., Eckermann-Reimer, L., Meyer-Schwesinger, C. & Ehmke, H. Acta Physiol (Oxf), e14246 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39445859
Time for differential weight management in heart failure. Anker, M. S., Porthun, J., Bayes-Genis, A. & Van Linthout, S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39453399
Subclassification of obesity for precision prediction of cardiometabolic diseases. Coral, D. E., Smit, F., Farzaneh, A., Gieswinkel, A., Tajes, J. F., Sparso, T., Delfin, C., Bauvin, P., Wang, K., Temprosa, M., De Cock, D., Blanch, J., Fernandez-Real, J. M., Ramos, R., Ikram, M. K., Gomez, M. F., Kavousi, M., Panova-Noeva, M., Wild, P. S., van der Kallen, C., Adriaens, M., van Greevenbroek, M., Arts, I., Le Roux, C., Ahmadizar, F., Frayling, T. M., Giordano, G. N., Pearson, E. R. & Franks, P. W. Nat Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39448862
Epigenetic associations with kidney disease in individuals of African ancestry with APOL1 high-risk genotypes and Human Immunodeficiency Virus. Hung, R. K. Y., Costeira, R., Chen, J., Schlosser, P., Grundner-Culemann, F., Booth, J. W., Sharpe, C. C., Bramham, K., Sun, Y. V., Marconi, V. C., Teumer, A., Winkler, C. A., Post, F. A. & Bell, J. T. Nephrol Dial Transplant (2024). https://www.ncbi.nlm.nih.gov/pubmed/39448372
Prognostic utility of mid-regional pro-adrenomedullin and growth differentiation factor 15 in patients undergoing transfemoral transcatheter aortic valve implantation. Piayda, K., Keranov, S., Schulz, L., Arsalan, M., Liebetrau, C., Kim, W. K., Hofmann, F. J., Bauer, P., Voss, S., Troidl, C., Sossalla, S. T., Hamm, C. W., Nef, H. M. & Dorr, O. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39453458
Potential benefits of aortic valve opening in patients with left ventricular assist devices. Romero Dorta, E., Meyn, R., Muller, M., Hoermandinger, C., Schoenrath, F., Falk, V., Meyer, A., Merke, N., Potapov, E., Mulzer, J. & Knierim, J. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/39450776
Plasma Protein Biomarkers and Long-Term Cardiovascular Mortality Risk in Patients With Chronic Coronary Heart Disease. Stewart, R. A. H., Robledo, K. P., Tonkin, A. M., Keech, A., Kritharides, L., Marschner, I., Janus, E., Thompson, P. L., Watts, G. F., Zeller, T., White, H. D. & Simes, J. J Am Heart Assoc 13, e034367 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39450716
SRSF2 safeguards efficient transcription of DNA damage and repair genes. Wagner, R. E., Arnetzl, L., Britto-Borges, T., Heit-Mondrzyk, A., Bakr, A., Sollier, E., Gkatza, N. A., Panten, J., Delaunay, S., Sohn, D., Schmezer, P., Odom, D. T., Muller-Decker, K., Plass, C., Dieterich, C., Lutsik, P., Bornelov, S. & Frye, M. Cell Rep 43, 114869 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39446588
Applicability of heart failure clinical practice guidelines in low- and middle-income countries. Zieroth, S., Giraldo, C. I. S., Pinto, F., Anker, S. D., Abraham, W. T., Atherton, J. J., Butler, J., Chopra, V., Coats, A. J. S., Dean, V., Filippatos, G., Zamorano, J. L., Zhang, Y., Weiskopf, R. B. & Colardelle, Y. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39453685
Comparison of exercise training modalities and change in peak oxygen consumption in heart failure with preserved ejection fraction: a secondary analysis of the OptimEx-Clin trial. Mueller, S., Kabelac, M., Fegers-Wustrow, I., Winzer, E. B., Gevaert, A. B., Beckers, P., Haller, B., Edelmann, F., Christle, J. W., Haykowsky, M. J., Sachdev, V., Kitzman, D. W., Linke, A., Adams, V., Wisloff, U., Pieske, B., van Craenenbroeck, E. & Halle, M. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39453789
Different risk and protective factors predict change of planning ability in middle versus older age. Unterrainer, J. M., Petersen, J., Schmidt, P., Ernst, M., Wirtz, M. A., Reinwarth, A. C., Wicke, F., Ghaemi Kerahrodi, J., Michal, M., Munzel, T., Konig, J., Lackner, K. J., Pfeiffer, N., Tuscher, O., Galle, P. R., Beutel, M. & Wild, P. S. Sci Rep 14, 25275 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39455694
Polygenic risk, aspirin and primary prevention of coronary artery disease. Yu, C., Natarajan, P., Patel, A. P., Bhatia, H. S., Khera, A. V., Neumann, J. T., Tsimikas, S., Wolfe, R., Nicholls, S. J., Reid, C. M., Zoungas, S., Tonkin, A. M., McNeil, J. J. & Lacaze, P. Eur Heart J Cardiovasc Pharmacother (2024). https://www.ncbi.nlm.nih.gov/pubmed/39455425
Aortic valve calcification volume and prognosis in patients undergoing transcatheter aortic valve implantation. Alvarez-Covarrubias, H. A., Altaner, N., Adolf, R., Jurisic, M., Horban, E., Pellegrini, C., Duesmann, C., Lachmann, M., Thilo, C., Syryca, F., Klos, M., Mayr, N. P., Rheude, T., Renker, M., Charitos, E. I., Schunkert, H., Kastrati, A., Xhepa, E., Won-Keun, K. & Joner, M. Rev Esp Cardiol (Engl Ed) (2024). https://www.ncbi.nlm.nih.gov/pubmed/39461471
Deep learning-based whole-brain B(1) (+)-mapping at 7T. Krueger, F., Aigner, C. S., Lutz, M., Riemann, L. T., Degenhardt, K., Hadjikiriakos, K., Zimmermann, F. F., Hammernik, K., Schulz-Menger, J., Schaeffter, T. & Schmitter, S. Magn Reson Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39462473
Subphenotypes of adult-onset diabetes: Data-driven clustering in the population-based KORA cohort. Dong, Q., Xi, Y., Brandmaier, S., Fuchs, M., Huemer, M. T., Waldenberger, M., Niu, J., Herder, C., Rathmann, W., Roden, M., Koenig, W., Bonhof, G. J., Gieger, C., Thorand, B., Peters, A., Rospleszcz, S. & Grallert, H. Diabetes Obes Metab 27, 338-347 (2025). https://www.ncbi.nlm.nih.gov/pubmed/39466719
Physiologists as medical scientists: An early warning from the German academic system. Streckfuss-Bomeke, K., Krankel, N., Maack, C., Schnabel, R. B., Zelarayan, L. C., Frey, N., Jezzard, P., Kruger, M., Lachmann, N., Lutz, S., Noack, C., Schoger, E., Schroder, K., Sommerfeld, L. C., Steffens, S., Winkels, H., Wurtz, C., Zeller, T., Rog-Zielinska, E. A. & Kohl, P. Physiol Rep 12, e70055 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39462686
Transcatheter Valve Repair for Tricuspid Regurgitation: 1-Year Results from a Large European Real-World Registry. Wild, M. G., Stolz, L., Rosch, S., Rudolph, F., Goebel, B., Koll, B., von Stein, P., Rottbauer, W., Rassaf, T., Beucher, H., Kraus, M., Kassar, M., Geisler, T., Ruck, A., Ferreira-Martins, J., Toggweiler, S., Sagmeister, P., Westermann, D., Stocker, T. J., Weckbach, L. T., Nabauer, M., Settergren, M., Dawkins, S., Kister, T., Praz, F., Vorpahl, M., Konstandin, M. H., Ludike, P., Kessler, M., Iliadis, C., Kalbacher, D., Lauten, P., Gercek, M., Besler, C., Lurz, P., Hausleiter, J. & Investigators, P. J Am Coll Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39466215
Implementation of a novel retrograde implantation technique for distal limb perfusion during extracorporeal cardiopulmonary resuscitation. Yildirim, Y., Kluge, S., Reichenspurner, H., Bernhardt, A. M., Pecha, S. & group, E. s. Intensive Care Med 50, 2190-2192 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39466379
Association analysis between an epigenetic alcohol risk score and blood pressure. Bui, H., Keshawarz, A., Wang, M., Lee, M., Ratliff, S. M., Lin, L., Birditt, K. S., Faul, J. D., Peters, A., Gieger, C., Delerue, T., Kardia, S. L. R., Zhao, W., Guo, X., Yao, J., Rotter, J. I., Li, Y., Liu, X., Liu, D., Tavares, J. F., Pehlivan, G., Breteler, M. M. B., Karabegovic, I., Ochoa-Rosales, C., Voortman, T., Ghanbari, M., van Meurs, J. B. J., Nasr, M. K., Dorr, M., Grabe, H. J., London, S. J., Teumer, A., Waldenberger, M., Weir, D. R., Smith, J. A., Levy, D., Ma, J. & Liu, C. Clin Epigenetics 16, 149 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39468603
Association of BMI with adherence and outcome in heart failure patients treated with wearable cardioverter defibrillator. Abumayyaleh, M., Koepsel, K., Erath, J. W., Kuntz, T., Klein, N., Kovacs, B., Duru, F., Saguner, A. M., Blockhaus, C., Shin, D. I., Kreimer, F., Gotzmann, M., Lapp, H., Beiert, T., Aweimer, A., Mugge, A., Weiss, C., El-Battrawy, I. & Akin, I. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39474928
Statistical methods for clinical trials interrupted by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic: A review. Basu, J., Parsons, N., Friede, T. & Stallard, N. Stat Methods Med Res 33, 2131-2143 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39474813
Safety of dobutamine stress cardiovascular magnetic resonance in patients with prior coronary artery bypass grafting. Heins, J., Salatzki, J., Kohrer, A., Ochs, A., Weberling, L. D., Hund, H., Giannitsis, E., Frey, N., Lossnitzer, D., Andre, F. & Steen, H. J Cardiovasc Magn Reson 26, 101119 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39471913
Comparison of strategies for vascular ACCESS closure after transcatheter aortic valve implantation: the ACCESS-TAVI randomized trial. Rheude, T., Ruge, H., Altaner, N., Pellegrini, C., Alvarez Covarrubias, H., Mayr, N. P., Cassese, S., Kufner, S., Taniguchi, Y., Thilo, C., Klos, M., Erlebach, M., Schneider, S., Jurisic, M., Laugwitz, K. L., Lange, R., Schunkert, H., Kastrati, A., Krane, M., Xhepa, E. & Joner, M. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39474906
Transcatheter Repair Versus Surgery for Atrial Versus Ventricular Functional Mitral Regurgitation - a Post-hoc Analysis of the MATTERHORN Trial. Rudolph, F., Geyer, M., Baldus, S., De Luca, V. M., Doenst, T., Pfister, R., Gummert, J., Kessler, M., Boekstegers, P., Lubos, E., Schroder, J., Thiele, H., Walther, T., Kelm, M., Hausleiter, J., Eitel, I., Fischer-Rasokat, U., Bufe, A., Schmeisser, A., Ince, H., Lurz, P., von Bardeleben, R. S., Hagl, C., Noack, T., Reith, S., Beucher, H., Reichenspurner, H., Rottbauer, W., Schulze, P. C., Muller, W., Frank, J., Michalik, C., Hellmich, M., Wahlers, T., Rudolph, V. & Iliadis, C. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39475706
Impact of Pulmonary Hypertension on Outcomes After Transcatheter Tricuspid Valve Edge-to-Edge Repair. Stolz, L., Kresoja, K. P., von Stein, J., Fortmeier, V., Koell, B., Rottbauer, W., Kassar, M., Goebel, B., Denti, P., Achouh, P., Rassaf, T., Barreiro-Perez, M., Boekstegers, P., Ruck, A., Doldi, P. M., Novotny, J., Zdanyte, M., Adamo, M., Vincent, F., Schlegel, P., von Bardeleben, R. S., Stocker, T. J., Weckbach, L. T., Wild, M. G., Besler, C., Brunner, S., Toggweiler, S., Grapsa, J., Patterson, T., Thiele, H., Kister, T., Tarantini, G., Masiero, G., De Carlo, M., Sticchi, A., Konstandin, M. H., Van Belle, E., Metra, M., Geisler, T., Estevez-Loureiro, R., Luedike, P., Karam, N., Maisano, F., Lauten, P., Praz, F., Kessler, M., Kalbacher, D., Rudolph, V., Iliadis, C., Lurz, P., Hausleiter, J. & Euro, T. R. I. JACC Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39474983
Enhanced platelet sensitization is accompanied by increased expression of the transporter MRP4 and elevated plasma S1P levels in mild COVID-19 convalescents. Tolksdorf, C., Seidel, A., Baume, C., Moritz, E., Salje, K., Lehmann, K., Becker, K., Garscha, U., Thiele, T., Schwedhelm, E., von Lucadou, M., Tzvetkov, M. V., Engeli, S., Jedlitschky, G. & Rauch, B. H. Platelets 35, 2413713 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39475058
Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities. von Haehling, S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39474945
Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke. Arlt, F. A., Sperber, P. S., von Rennenberg, R., Gebert, P., Teegen, B., Georgakis, M. K., Fang, R., Dewenter, A., Gortler, M., Petzold, G. C., Wunderlich, S., Zerr, I., Dichgans, M., Pruss, H., Endres, M. & Investigators, D. Mol Psychiatry (2024). https://www.ncbi.nlm.nih.gov/pubmed/39478168
September
Paper of the Month
Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy
DZHK-Autor:innen: Stephan E Lehnart, Sören Brandenburg, Tobias Kohl, Anastasiia Gorshkova, Jasper Wedemeyer, Gerd Hasenfuß, Carolin Fleischhacker, Christof Lenz
Percutaneous Transcatheter Edge-to-Edge Repair for Functional Mitral Regurgitation in Heart Failure: A Meta-Analysis of 3 Randomized Controlled Trials. Anker, M. S., Porthun, J., Schulze, P. C., Rassaf, T. & Landmesser, U. J Am Coll Cardiol 84, 2364-2368 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217568
Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation. Anker, S. D., Friede, T., von Bardeleben, R. S., Butler, J., Khan, M. S., Diek, M., Heinrich, J., Geyer, M., Placzek, M., Ferrari, R., Abraham, W. T., Alfieri, O., Auricchio, A., Bayes-Genis, A., Cleland, J. G. F., Filippatos, G., Gustafsson, F., Haverkamp, W., Kelm, M., Kuck, K. H., Landmesser, U., Maggioni, A. P., Metra, M., Ninios, V., Petrie, M. C., Rassaf, T., Ruschitzka, F., Schafer, U., Schulze, P. C., Spargias, K., Vahanian, A., Zamorano, J. L., Zeiher, A., Karakas, M., Koehler, F., Lainscak, M., Oner, A., Mezilis, N., Theofilogiannakos, E. K., Ninios, I., Chrissoheris, M., Kourkoveli, P., Papadopoulos, K., Smolka, G., Wojakowski, W., Reczuch, K., Pinto, F. J., Wiewiorka, L., Kalarus, Z., Adamo, M., Santiago-Vacas, E., Ruf, T. F., Gross, M., Tongers, J., Hasenfuss, G., Schillinger, W., Ponikowski, P. & Investigators, R.-H. N Engl J Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39216092
Transcatheter Repair versus Mitral-Valve Surgery for Secondary Mitral Regurgitation. Baldus, S., Doenst, T., Pfister, R., Gummert, J., Kessler, M., Boekstegers, P., Lubos, E., Schroder, J., Thiele, H., Walther, T., Kelm, M., Hausleiter, J., Eitel, I., Fischer-Rasokat, U., Bufe, A., Schmeisser, A., Ince, H., Lurz, P., von Bardeleben, R. S., Hagl, C., Noack, T., Reith, S., Beucher, H., Reichenspurner, H., Rottbauer, W., Schulze, P. C., Muller, W., Frank, J., Hellmich, M., Wahlers, T., Rudolph, V. & Investigators, M. N Engl J Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39216093
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is reduced with preeclampsia and small for gestational aged fetuses. Bartho, L. A., Walker, S. P., Cannon, P., Nguyen, T. V., Nguyen, A., Botha, S. M., Hannan, N. J., Tong, S. & Kaitu'u-Lino, T. J. Placenta 156, 10-13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39216164
Non-HDL-cholesterol reduction: the challenges of applying clinical trial results in the real world. De Geest, B. & Van Linthout, S. Eur Heart J 45, 4216-4218 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217498
Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study. Fabritz, L., Al-Taie, C., Borof, K., Breithardt, G., Camm, A. J., Crijns, H., Roth Cardoso, V., Chua, W., van Elferen, S., Eckardt, L., Gkoutos, G., Goette, A., Guasch, E., Hatem, S., Metzner, A., Mont, L., Murukutla, V. A., Obergassel, J., Rillig, A., Sinner, M. F., Schnabel, R. B., Schotten, U., Sommerfeld, L. C., Wienhues-Thelen, U. H., Zapf, A., Zeller, T. & Kirchhof, P. Eur Heart J 45, 5002-5019 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39215973
Impaired glucose metabolism and the risk of vascular events and mortality after ischemic stroke: A systematic review and meta-analysis. Kaynak, N., Kennel, V., Rackoll, T., Schulze, D., Endres, M. & Nave, A. H. Cardiovasc Diabetol 23, 323 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217364
Hospitalization of Symptomatic Patients With Heart Failure and Moderate to Severe Functional Mitral Regurgitation Treated With MitraClip: Insights From RESHAPE-HF2. Ponikowski, P., Friede, T., von Bardeleben, R. S., Butler, J., Shahzeb Khan, M., Diek, M., Heinrich, J., Geyer, M., Placzek, M., Ferrari, R., Abraham, W. T., Alfieri, O., Auricchio, A., Bayes-Genis, A., Cleland, J. G. F., Filippatos, G., Gustafsson, F., Haverkamp, W., Kelm, M., Kuck, K. H., Landmesser, U., Maggioni, A. P., Metra, M., Ninios, V., Petrie, M. C., Rassaf, T., Ruschitzka, F., Schafer, U., Schulze, P. C., Spargias, K., Vahanian, A., Zamorano, J. L., Zeiher, A., Karakas, M., Koehler, F., Lainscak, M., Oner, A., Mezilis, N., Theofilogiannakos, E. K., Ninios, I., Chrissoheris, M., Kourkoveli, P., Papadopoulos, K., Smolka, G., Wojakowski, W., Reczuch, K., Pinto, F. J., Wiewiorka, L., Streb, W., Adamo, M., Santiago-Vacas, E., Friedrich Ruf, T., Gross, M., Tongers, J., Hasenfuss, G., Schillinger, W. & Anker, S. D. J Am Coll Cardiol 84, 2347-2363 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217574
Temporal Trends in Takotsubo Syndrome: Results From the International Takotsubo Registry. Schweiger, V., Cammann, V. L., Crisci, G., Gilhofer, T., Schlenker, R., Niederseer, D., Chen, S., Ebrahimi, R., Wenzl, F., Wurdinger, M., Citro, R., Vecchione, C., Gili, S., Neuhaus, M., Franke, J., Meder, B., Jaguszewski, M., Noutsias, M., Knorr, M., Jansen, T., D'Ascenzo, F., Dichtl, W., von Lewinski, D., Burgdorf, C., Kherad, B., Tschope, C., Sarcon, A., Shinbane, J., Rajan, L., Michels, G., Pfister, R., Cuneo, A., Jacobshagen, C., Karakas, M., Koenig, W., Pott, A., Meyer, P., Roffi, M., Banning, A., Wolfrum, M., Cuculi, F., Kobza, R., Fischer, T. A., Vasankari, T., Airaksinen, K. E. J., Napp, L. C., Dworakowski, R., MacCarthy, P., Kaiser, C., Osswald, S., Galiuto, L., Chan, C., Bridgman, P., Beug, D., Delmas, C., Lairez, O., Gilyarova, E., Shilova, A., Gilyarov, M., El-Battrawy, I., Akin, I., Polednikova, K., Tousek, P., Winchester, D. E., Massoomi, M., Galuszka, J., Ukena, C., Poglajen, G., Carrilho-Ferreira, P., Hauck, C., Paolini, C., Bilato, C., Kobayashi, Y., Kato, K., Ishibashi, I., Himi, T., Din, J., Al-Shammari, A., Prasad, A., Rihal, C. S., Liu, K., Schulze, P. C., Bianco, M., Jorg, L., Rickli, H., Pestana, G., Nguyen, T. H., Bohm, M., Maier, L. S., Pinto, F. J., Widimsky, P., Felix, S. B., Braun-Dullaeus, R. C., Rottbauer, W., Hasenfuss, G., Pieske, B. M., Schunkert, H., Budnik, M., Opolski, G., Thiele, H., Bauersachs, J., Horowitz, J. D., Di Mario, C., Kong, W., Dalakoti, M., Imori, Y., Munzel, T., Liberale, L., Montecucco, F., Bax, J. J., Crea, F., Ruschitzka, F., Luscher, T. F., Ghadri, J. R., Bossone, E., Templin, C. & Di Vece, D. J Am Coll Cardiol 84, 1178-1189 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217551
Sex-specific Prediction of Cardiogenic Shock After Acute Coronary Syndromes: The SEX-SHOCK Score. Wang, Y., Zeller, M., Auffret, V., Georgiopoulos, G., Raber, L., Roffi, M., Templin, C., Muller, O., Liberale, L., Ministrini, S., Stamatelopoulos, K., Stellos, K., Camici, G. G., Montecucco, F., Rickli, H., Maza, M., Radovanovic, D., Cottin, Y., Chague, F., Niederseer, D., Luscher, T. F. & Kraler, S. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217456
Glycoprotein IIb/IIIa inhibitors in acute myocardial infarction and angiographic microvascular obstruction: the REVERSE-FLOW trial. Eitel, I., Saraei, R., Jurczyk, D., Fach, A., Hambrecht, R., Wienbergen, H., Frerker, C., Schmidt, T., Allali, A., Joost, A., Marquetand, C., Kurz, T., Haaf, P., Fahrni, G., Mueller, C., Desch, S., Thiele, H. & Stiermaier, T. Eur Heart J 45, 5058-5067 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217605
Do DanGer-SHOCK-like patients benefit from VA-ECMO treatment in infarct-related cardiogenic shock? results of an individual patient data meta-analysis. Zeymer, U., Freund, A., Hochadel, M., Ostadal, P., Belohlavek, J., Massberg, S., Brunner, S., Flather, M., Adlam, D., Hassager, C., Moeller, J. E., Schneider, S., Desch, S. & Thiele, H. Eur Heart J Acute Cardiovasc Care 13, 658-661 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39217624
Temporal trends and outcomes of acute ischaemic strokes in patients hospitalised for percutaneous coronary intervention. Bay, B., Gossling, A., Remmel, M., Becher, P. M., Schrage, B., Rimmele, D. L., Thomalla, G., Blankenberg, S., Clemmensen, P., Brunner, F. J. & Waldeyer, C. EuroIntervention 20, e1098-e1106 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39219362
Routine extracorporeal life support in infarct-related cardiogenic shock: 1-year results of the ECLS-SHOCK trial. Desch, S., Zeymer, U., Akin, I., Behnes, M., Duerschmied, D., Rassaf, T., Mahabadi, A. A., Lehmann, R., Eitel, I., Graf, T., Seidler, T., Schuster, A., Thevathasan, T., Skurk, C., Clemmensen, P., Hennersdorf, M., Fichtlscherer, S., Voigt, I., Seyfarth, M., John, S., Ewen, S., Linke, A., Tigges, E., Nordbeck, P., Bruch, L., Jung, C., Franz, J., Lauten, P., Noc, M., Fuernau, G., Feistritzer, H. J., Poss, J., Kirchhof, E., Ouarrak, T., Schneider, S., Freund, A. & Thiele, H. Eur Heart J 45, 4200-4203 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39219338
Rare Genetic Variants in LDLR, APOB, and PCSK9 are Associated with Aortic Stenosis. Ramo, J., Jurgens, S. J., Kany, S., Choi, S. H., Wang, X., Smirnov, A. N., Friedman, S. F., Maddah, M., Khurshid, S., Ellinor, P. T. & Pirruccello, J. P. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39222019
Anticoagulation in device-detected atrial fibrillation with or without vascular disease: a combined analysis of the NOAH-AFNET 6 and ARTESiA trials. Schnabel, R. B., Benezet-Mazuecos, J., Becher, N., McIntyre, W. F., Fierenz, A., Lee, S. F., Goette, A., Atar, D., Bertaglia, E., Benz, A. P., Chlouverakis, G., Birnie, D. H., Dichtl, W., Blomstrom-Lundqvist, C., Camm, A. J., Erath, J. W., Simantirakis, E., Kutyifa, V., Lip, G. Y. H., Mabo, P., Marijon, E., Rivard, L., Schotten, U., Alings, M., Sehner, S., Toennis, T., Linde, C., Vardas, P., Granger, C. B., Zapf, A., Lopes, R. D., Healey, J. S. & Kirchhof, P. Eur Heart J 45, 4902-4916 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39222018
The next era of gene-specific clinical care in patients with dilated cardiomyopathy. Verdonschot, J. A. J., Heymans, S. R. B. & Van Linthout, S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39219297
Finerenone and left ventricular hypertrophy in chronic kidney disease and type 2 diabetes. Filippatos, G., Anker, S. D., Bakris, G. L., Rossing, P., Ruilope, L. M., Coats, A. J. S., von Haehling, S., Ponikowski, P., Rosano, G. M. C., Brinker, M., Farjat, A. E., Roberts, L., Pitt, B., Fidelio, D. K. D. & investigators, F.-D. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39226189
Immuno-related cardio-vascular adverse events associated with immuno-oncological treatments: an under-estimated threat for cancer patients. Panuccio, G., Correale, P., d'Apolito, M., Mutti, L., Giannicola, R., Pirtoli, L., Giordano, A., Labate, D., Macheda, S., Carabetta, N., Abdelwahed, Y. S., Landmesser, U., Tassone, P., Tagliaferri, P., De Rosa, S. & Torella, D. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39225869
Investigating the Heterogeneity of "Study Twins". Rover, C. & Friede, T. Biom J66, e202300387 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39223907
Heart Failure Risk Assessment Using Biomarkers in Patients With Atrial Fibrillation: Analysis From COMBINE-AF. Haller, P. M., Jarolim, P., Palazzolo, M. G., Bellavia, A., Antman, E. M., Eikelboom, J., Granger, C. B., Harrington, J., Healey, J. S., Hijazi, Z., Patel, M. R., Patel, S. M., Ruff, C. T., Wallentin, L., Braunwald, E., Giugliano, R. P. & Morrow, D. A. J Am Coll Cardiol 84, 1528-1540 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39230543
Navigating the heart - insights into human coronary artery innervation. Joner, M. & Beele, A. EuroIntervention 20, e1056-e1058 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39229836
Antibodies and complement are key drivers of thrombosis. Stark, K., Kilani, B., Stockhausen, S., Busse, J., Schubert, I., Tran, T. D., Gaertner, F., Leunig, A., Pekayvaz, K., Nicolai, L., Fumagalli, V., Stermann, J., Stephan, F., David, C., Muller, M. B., Heyman, B., Lux, A., da Palma Guerreiro, A., Frenzel, L. P., Schmidt, C. Q., Dopler, A., Moser, M., Chandraratne, S., von Bruhl, M. L., Lorenz, M., Korff, T., Rudelius, M., Popp, O., Kirchner, M., Mertins, P., Nimmerjahn, F., Iannacone, M., Sperandio, M., Engelmann, B., Verschoor, A. & Massberg, S. Immunity57, 2140-2156 e2110 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39226900
An hepatitis B and D virus infection model using human pluripotent stem cell-derived hepatocytes. Chi, H., Qu, B., Prawira, A., Richardt, T., Maurer, L., Hu, J., Fu, R. M., Lempp, F. A., Zhang, Z., Grimm, D., Wu, X., Urban, S. & Dao Thi, V. L. EMBO Rep 25, 4311-4336 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39232200
Elastin-specific MR probe for visualization and evaluation of an interleukin-1beta targeted therapy for atherosclerosis. Mangarova, D. B., Reimann, C., Kaufmann, J. O., Mockel, J., Kader, A., Adams, L. C., Ludwig, A., Onthank, D., Robinson, S., Karst, U., Helmer, R., Botnar, R., Hamm, B., Makowski, M. R. & Brangsch, J. Sci Rep 14, 20648 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39232217
Transfemoral or surgical aortic valve replacement in young low-risk patients with tricuspid and bicuspid aortic valve stenosis. Schofer, N. & Blankenberg, S. Eur Heart J 45, 3815-3817 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39235157
Refined movement analysis in the staircase test reveals differential motor deficits in mouse models of stroke. Skrobot, M., Sa, R., Walter, J., Vogt, A., Paulat, R., Lips, J., Mosch, L., Mueller, S., Dominiak, S., Sachdev, R., Boehm-Sturm, P., Dirnagl, U., Endres, M., Harms, C. & Wenger, N. J Cereb Blood Flow Metab 44, 1551-1564 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39234984
Right ventricular function and dimensions in patients undergoing transcatheter aortic valve replacement assessed by three-dimensional echocardiography. Stolz, L., Schmid, S., Steffen, J., Doldi, P. M., Theiss, H. D., Low, K., Haum, M., Massberg, S., Hausleiter, J. & Deseive, S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39235495
Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome. Haunhorst, S., Dudziak, D., Scheibenbogen, C., Seifert, M., Sotzny, F., Finke, C., Behrends, U., Aden, K., Schreiber, S., Brockmann, D., Burggraf, P., Bloch, W., Ellert, C., Ramoji, A., Popp, J., Reuken, P., Walter, M., Stallmach, A. & Puta, C. Infection (2024). https://www.ncbi.nlm.nih.gov/pubmed/39240417
Long term safety and outcomes after atrial shunting for heart failure with preserved or mildly reduced ejection fraction: 5-year and 3-year follow-up in the REDUCE LAP-HF I and II trials. Litwin, S. E., Komtebedde, J., Borlaug, B. A., Kaye, D. M., Hasenfubeta, G., Kawash, R., Hoendermis, E., Hummel, S. L., Cikes, M., Gustafsson, F., Chung, E., Mohan, R., Sverdlov, A. L., Swarup, V., Winkler, S., Hayward, C. S., Bergmann, M. W., Bugger, H., McKenzie, S., Nair, A., Rieth, A., Burkhoff, D., Cutlip, D. E., Solomon, S. D., van Veldhuisen, D. J., Leon, M. B. & Shah, S. J. Am Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39237070
Development and validation of a questionnaire on bodily experience in VAD patients (BE-S). Richter, F., Kugler, C., Tigges-Limmer, K. & Albert, W. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/39239770
Evaluation of a digital therapy programme for the treatment of primary arterial hypertension: eXPLORE - study protocol for a fully decentralised randomised controlled feasibility study. Schlichtiger, J., Struven, A., Massberg, S., von Degenfeld, G., Leber, A., Weyh, P., Meyer, J., Brunner, S. & Stremmel, C. BMJ Open 14, e081347 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39237273
Outcome after ablation of atypical atrial flutter: Is induction a feasible approach? Vonderlin, N., Siebermair, J., Mahabadi, A. A., Dobrev, D., Rassaf, T., Wakili, R. & Kochhaeuser, S. Int J Cardiol Heart Vasc 54, 101489 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39238839
Neurofilament light chain as a biomarker of chemotherapy-induced peripheral neuropathy. Andersen, N. E., Boehmerle, W., Huehnchen, P. & Stage, T. B. Trends Pharmacol Sci 45, 872-879 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39242335
Semi-automated reproducible target transfer for cardiac radioablation - A multi-center cross-validation study within the RAVENTA trial. Hohmann, S., Xie, J., Eckl, M., Grehn, M., Karfoul, N., Janorschke, C., Merten, R., Rudic, B., Buergy, D., Lyan, E., Krug, D., Mehrhof, F., Boldt, L. H., Corradini, S., Fanslau, H., Kaestner, L., Zaman, A., Giordano, F. A., Duncker, D., Dunst, J., Tilz, R. R., Schweikard, A., Blanck, O. & Boda-Heggemann, J. Radiother Oncol 200, 110499 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39242029
Percutaneous Edge-to-Edge Repair for Tricuspid Regurgitation: 3-Year Outcomes From the TRILUMINATE Study. Nickenig, G., Lurz, P., Sorajja, P., von Bardeleben, R. S., Sitges, M., Tang, G. H. L., Hausleiter, J., Trochu, J. N., Nabauer, M., Heitkemper, M., Ying, S. W., Weber, M., Hahn, R. T. & Investigators, T. JACC Cardiovasc Interv17, 2113-2122 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39243264
Comparative electron microscopic visualization of the lung alveolar epithelial glycocalyx with different staining and labeling methods. Gluhovic, V., Timm, S., Kuebler, W. M., Lopez-Rodriguez, E. & Ochs, M. J Anat (2024). https://www.ncbi.nlm.nih.gov/pubmed/39245632
Rational approximation of golden angles: Accelerated reconstructions for radial MRI. Scholand, N., Schaten, P., Graf, C., Mackner, D., Holme, H. C. M., Blumenthal, M., Mao, A., Asslander, J. & Uecker, M. Magn Reson Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39250418
Burden of disease in Germany attributed to ambient particulate matter pollution : Findings from the Global Burden of Disease Study 2019. Hahad, O., Lelieveld, J., Al-Kindi, S., Schmitt, V. H., Hobohm, L., Keller, K., Roosli, M., Kuntic, M. & Daiber, A. Herz (2024). https://www.ncbi.nlm.nih.gov/pubmed/39254857
Effect of Bimagrumab on body composition: a systematic review and meta-analysis. Kanbay, M., Siriopol, D., Copur, S., Hasbal, N. B., Guldan, M., Kalantar-Zadeh, K., Garfias-Veitl, T. & von Haehling, S. Aging Clin Exp Res 36, 185 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39251484
Troponin Elevation in Asymptomatic Cancer Patients: Unveiling Connections and Clinical Implications. Romann, S. W., Giannitsis, E., Frey, N. & Lehmann, L. H. Curr Heart Fail Rep (2024). https://www.ncbi.nlm.nih.gov/pubmed/39254897
Metformin modulates microbiota and improves blood pressure and cardiac remodeling in a rat model of hypertension. Wimmer, M. I., Bartolomaeus, H., Anandakumar, H., Chen, C. Y., Vecera, V., Kedziora, S., Kamboj, S., Schumacher, F., Pals, S., Rauch, A., Meisel, J., Potapenko, O., Yarritu, A., Bartolomaeus, T. U. P., Samaan, M., Thiele, A., Sturzbecher, L., Geisberger, S. Y., Kleuser, B., Oefner, P. J., Haase, N., Lober, U., Gronwald, W., Forslund-Startceva, S. K., Muller, D. N. & Wilck, N. Acta Physiol (Oxf), e14226 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39253815
Subclinical impairment of the left atrium is associated with MRI-based lung volume but not with parameters from pulmonary function testing. Wintergerst, C., Lorbeer, R., Mujaj, B., Bulwer, B. E., Rospleszcz, S., Askani, E., Schulz, H., Karrasch, S., Peters, A., Schlett, C. L., Bamberg, F. & von Kruchten, R. Sci Rep 14, 21054 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39251644
Potential deprescribing indications for antidepressants between 2012 and 2019: repeated cross-sectional analysis in two Scottish health boards. Brisnik, V., Rottenkolber, M., Vukas, J., Schechner, M., Lukaschek, K., Jung-Sievers, C., Gensichen, J., Thiem, U., Drey, M., Kruger, N., Mair, A., Guthrie, B., Fischer, S., Dreischulte, T. & Group, P. S. BMC Med 22, 378 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39256761
Associations of occupational and leisure-time physical activity with all-cause mortality: an individual participant data meta-analysis. Coenen, P., Huysmans, M. A., Holtermann, A., Troiano, R. P., Mork, P. J., Krokstad, S., Clays, E., Cillekens, B., De Bacquer, D., Aadahl, M., Karhus, L. L., Sjol, A., Andersen, L. B., Kauhanen, J., Voutilainen, A., Pulsford, R. M., Stamatakis, E., Goldbourt, U., Peters, A., Thorand, B., Rosengren, A., Bjorck, L., Sprow, K., Franzon, K., Rodriguez-Barranco, M., Lujan-Barroso, L., Knutsson, A., Alfredsson, L., Bahls, M., Ittermann, T., Kluttig, A., Hassan, L., Wanner, M., Bopp, M., Marott, J. L., Schnohr, P., Nordestgaard, B. G., Dalene, K. E., Ekelund, U., Clausen, J., Jensen, M. T., Petersen, C. B., Krause, N., Twisk, J., Mechelen, W. V. & van der Beek, A. J. Br J Sports Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39255999
EASIX (endothelial activation and stress index) predicts mortality in patients with coronary artery disease. Finke, D., Hund, H., Frey, N., Luft, T. & Lehmann, L. H. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39256221
Incremental value of blood-based markers of liver fibrosis in cardiovascular risk stratification. Georgiopoulos, G., Athanasopoulos, S., Mavraganis, G., Konstantaki, C., Papaioannou, M., Delialis, D., Angelidakis, L., Sachse, M., Papoutsis, D., Cavlan, B., Tual-Chalot, S., Zervas, G., Sopova, K., Mitrakou, A., Stellos, K. & Stamatelopoulos, K. J Clin Endocrinol Metab (2024). https://www.ncbi.nlm.nih.gov/pubmed/39257198
Immune mediators in heart-lung communication. Gillan, J. L., Jaeschke, L., Kuebler, W. M. & Grune, J. Pflugers Arch (2024). https://www.ncbi.nlm.nih.gov/pubmed/39256247
Heart failure in Europe: Guideline-directed medical therapy use and decision making in chronic and acute, pre-existing and de novo, heart failure with reduced, mildly reduced, and preserved ejection fraction - the ESC EORP Heart Failure III Registry. Lund, L. H., Crespo-Leiro, M. G., Laroche, C., Zaliaduonyte, D., Saad, A. M., Fonseca, C., Celutkiene, J., Zdravkovic, M., Bielecka-Dabrowa, A. M., Agostoni, P., Xuereb, R. G., Neronova, K. V., Lelonek, M., Cavusoglu, Y., Gellen, B., Abdelhamid, M., Hammoudi, N., Anker, S. D., Chioncel, O., Filippatos, G., Lainscak, M., McDonagh, T. A., Mebazaa, A., Piepoli, M., Ruschitzka, F., Seferovic, P. M., Savarese, G., Metra, M., Rosano, G. M. C., Maggioni, A. P., Leaders, E. E. H. I. N. & Investigators. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39257278
Influence of implantation strategy in the transition from temporary left ventricular assist device to durable mechanical circulatory support. Meyer, A. L., Lewin, D., Billion, M., Hofmann, S., Netuka, I., Belohlavek, J., Jawad, K., Saeed, D., Schmack, B., Rojas Hernandez, V., Gummert, J., Bernhardt, A., Farber, G., Kooij, J., Meyns, B., Loforte, A., Pieri, M., Scandroglio, A. M., Akhyari, P., Szymanski, M. K., Moeller, C. J. H., Gustafsson, F., Medina, M., Oezkur, M., Zimpfer, D., Krasivskyi, I., Djordjevic, I., Haneya, A., Stein, J., Lanmueller, P., Potapov, E. V. & Kremer, J. Eur J Cardiothorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39259187
Influence of implant strategy on the transition from temporary left ventricular assist device to durable mechanical circulatory support. Meyer, A. L., Lewin, D., Billion, M., Hofmann, S., Netuka, I., Belohlavek, J., Jawad, K., Saeed, D., Schmack, B., Rojas, S. V., Gummert, J., Bernhardt, A., Farber, G., Kooij, J., Meyns, B., Loforte, A., Pieri, M., Scandroglio, A. M., Akhyari, P., Szymanski, M. K., Moller, C. H., Gustafsson, F., Medina, M., Oezkur, M., Zimpfer, D., Krasivskyi, I., Djordjevic, I., Haneya, A., Stein, J., Lanmueller, P., Potapov, E. V. & Kremer, J. Eur J Cardiothorac Surg 66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39259187
The association between gout and subsequent cardiovascular events: a retrospective cohort study with 132,000 using propensity score matching in primary care outpatients in Germany. Sedighi, J., Luedde, M., Gaensbacher-Kunzendorf, J., Sossalla, S. & Kostev, K. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39256222
Effects of SGLT2 inhibitors on parameters of renal venous congestion in intrarenal Doppler ultrasonography. Wallbach, M., Ajrab, J., Bayram, B., Pieper, D., Schafer, A. K., Luders, S., Delistefani, F., Muller, D. & Koziolek, M. Clin Kidney J 17, sfae234 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39258260
Short-term vital parameter forecasting in the intensive care unit: A benchmark study leveraging data from patients after cardiothoracic surgery. Hinrichs, N., Roeschl, T., Lanmueller, P., Balzer, F., Eickhoff, C., O'Brien, B., Falk, V. & Meyer, A. PLOS Digit Health 3, e0000598 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39264979
A gender perspective on diet, microbiome, and sex hormone interplay in cardiovascular disease. Jovanovic, N., Zach, V., Crocini, C., Bahr, L. S., Forslund-Startceva, S. K. & Franz, K. Acta Physiol (Oxf), e14228 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39263901
Renin angiotensin system inhibitors and outcome in patients with Takotsubo syndrome: a propensity score analysis of the GEIST registry. Santoro, F., Stiermaier, T., Gil, I. J. N., El-Battrawy, I., Patz, T., Cacciotti, L., Guerra, F., Novo, G., Musumeci, B., Volpe, M., Mariano, E., Caldarola, P., Montisci, R., Ragnatela, I., Cetera, R., Vazirani, R., Lluch, C., Uribarri, A., Corbi-Pascual, M., Cardona, D. A. C., Akin, I., Barbato, E., Thiele, H., Brunetti, N. D., Eitel, I. & Arcari, L. Am Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39260785
PDE8 Inhibition and Its Impact on ICa,L in Persistent Atrial Fibrillation: Evaluation of PDE8 as a Potential Drug Target. Ismaili, D., Petersen, J., Schulz, C., Eschenhagen, T., Koivumaki, J. T. & Christ, T. J Cardiovasc Pharmacol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39270009
A Bayesian Reanalysis of the CULPRIT-SHOCK Trial. Jung, C., Wernly, B., Masyuk, M., Kelm, M., Freund, A., Poss, J., Desch, S., Schneider, S., Akin, I., Schlesinger, S., Schrage, B., Zeymer, U. & Thiele, H. Eur Heart J Acute Cardiovasc Care (2024). https://www.ncbi.nlm.nih.gov/pubmed/39268887
Recruiting people with selected citizenships for the health interview survey GEDA Fokus throughout Germany: evaluation of recruitment efforts and recommendations for future research. Koschollek, C., Gaertner, B., Geerlings, J., Kuhnert, R., Mauz, E. & Hovener, C. BMC Med Res Methodol 24, 200 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39266952
Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Sachs, S., Gotz, A., Finan, B., Feuchtinger, A., DiMarchi, R. D., Doring, Y., Weber, C., Tschop, M. H., Muller, T. D. & Hofmann, S. M. Cardiovasc Diabetol 23, 341 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39267039
Atrial hiPSC-CM as a pharmacological model to evaluate anti-AF drugs: Some lessons from IKur. Schulz, C., Eschenhagen, T. & Christ, T. J Cardiovasc Pharmacol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39270001
The innate immune regulator MyD88 dampens fibrosis during zebrafish heart regeneration. Goumenaki, P., Gunther, S., Kikhi, K., Looso, M., Marin-Juez, R. & Stainier, D. Y. R. Nat Cardiovasc Res 3, 1158-1176 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39271818
Pericyte-to-Endothelial Cell Communication via Tunneling Nanotubes Is Disrupted by a Diol of Docosahexaenoic Acid. Kempf, S., Popp, R., Naeem, Z., Fromel, T., Wittig, I., Klatt, S. & Fleming, I. Cells 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39273001
Inflammation and Fibrosis in Progeria: Organ-Specific Responses in an HGPS Mouse Model. Kruger, P., Schroll, M., Fenzl, F., Lederer, E. M., Hartinger, R., Arnold, R., Cagla Togan, D., Guo, R., Liu, S., Petry, A., Gorlach, A. & Djabali, K. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39273272
MASTER-NAADP: a membrane permeable precursor of the Ca(2+) mobilizing second messenger NAADP. Krukenberg, S., Mockl, F., Weiss, M., Dekiert, P., Hofmann, M., Gerlach, F., Winterberg, K. J., Kovacevic, D., Khansahib, I., Troost, B., Hinrichs, M., Granato, V., Nawrocki, M., Hub, T., Tsvilovskyy, V., Medert, R., Woelk, L. M., Forster, F., Li, H., Werner, R., Altfeld, M., Huber, S., Clarke, O. B., Freichel, M., Diercks, B. P., Meier, C. & Guse, A. H. Nat Commun 15, 8008 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39271671
LncRNAs Are Key Regulators of Transcription Factor-Mediated Endothelial Stress Responses. Lam, F., Leisegang, M. S. & Brandes, R. P. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39273673
The Effect of Individual Attitude toward Healthy Nutrition on Adherence to a High-UFA and High-Protein Diet: Results of a Randomized Controlled Trial. Nguyen, T. H., Pletsch-Borba, L., Feindt, P. H., Stokes, C. S., Pohrt, A., Meyer, N. M. T., Wernicke, C., Sommer-Ballarini, M., Apostolopoulou, K., Hornemann, S., Grune, T., Bruck, T., Pfeiffer, A. F. H., Spranger, J. & Mai, K. Nutrients 16 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39275358
ACE2 Knockout Mice Are Resistant to High-Fat Diet-Induced Obesity in an Age-Dependent Manner. Nunes-Souza, V., Alenina, N., Qadri, F., Mosienko, V., Santos, R. A. S., Bader, M. & Rabelo, L. A. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39273464
Author Correction: GPR15-mediated T cell recruitment during acute viral myocarditis facilitated virus elimination and improved outcome. Stoffers, B., Wolf, H., Bacmeister, L., Kupsch, S., Vico, T., Marchini, T., Brehm, M. A., Yan, I., Becher, P. M., Ardeshirdavani, A., Escher, F., Kim, S. V., Klingel, K., Kirchhof, P., Blankenberg, S., Zeller, T., Wolf, D., Hilgendorf, I., Westermann, D. & Lindner, D. Nat Cardiovasc Res 3, 1177 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39271820
RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions. Weiss, L. M., Warwick, T., Zehr, S., Gunther, S., Wolf, S., Schmachtel, T., Izquierdo Ponce, J., Palfi, K., Teichmann, T., Schneider, A., Stotzel, J., Knapp, S., Weigert, A., Savai, R., Rieger, M. A., Oellerich, T., Wittig, I., Oo, J. A., Brandes, R. P. & Leisegang, M. S. Commun Biol 7, 1131 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39271940
Shaping the future of heart health. Cheng, A. Y. Y., Zhang, S., von Haehling, S. & Desai, M. Med 5, 1035-1037 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39276765
Should workers be physically active after work? Associations of leisure-time physical activity with cardiovascular and all-cause mortality across occupational physical activity levels-An individual participant data meta-analysis. Cillekens, B., Coenen, P., Huysmans, M. A., Holtermann, A., Troiano, R. P., Mork, P. J., Krokstad, S., Clays, E., De Bacquer, D., Aadahl, M., Karhus, L. L., Sjol, A., Bo Andersen, L., Kauhanen, J., Voutilainen, A., Pulsford, R., Stamatakis, E., Goldbourt, U., Peters, A., Thorand, B., Rosengren, A., Bjorck, L., Sprow, K., Franzon, K., Rodriguez-Barranco, M., Lujan-Barroso, L., Alfredsson, L., Bahls, M., Ittermann, T., Wanner, M., Bopp, M., Marott, J. L., Schnohr, P., Nordestgaard, B. G., Dalene, K. E., Ekelund, U., Clausen, J., Jensen, M. T., Petersen, C. B., Krause, N., Twisk, J., van Mechelen, W. & van der Beek, A. J. J Sport Health Sci, 100987 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39277081
Cardiovascular and Renal Treatment in Heart Failure Patients with Hyperkalemia or High Risk of Hyperkalemia: Rationale and Design of the CARE-HK in HF Registry. Greene, S. J., Bohm, M., Bozkurt, B., Butler, J., Cleland, J. G., Coats, A. J., Desai, N. R., Grobbee, D. E., Kelepouris, E., Pinto, F., Rosano, G., Morin, I., Szecsody, P., Fabien, S., Waechter, S., Crespo-Leiro, M. G., Hulsmann, M., Kempf, T., Pfister, O., Pouleur, A. C., Sauer, A. J., Saxena, M., Schulz, M., Volterrani, M., Anker, S. D. & Kosiborod, M. N. J Card Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39277029
Endothelial epoxyeicosatrienoic acid release is intact in aldosterone excess. Meng, Y., Bilyal, A., Chen, L., Mederos, Y. S. M., Kocabiyik, J., Gudermann, T., Riols, F., Haid, M., Marques, J. G., Horak, J., Koletzko, B., Sun, J., Beuschlein, F., Heinrich, D. A., Adolf, C., Reincke, M. & Schneider, H. Atherosclerosis 398, 118591 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39277963
Chronic Activation of Tubulin Tyrosination Improves Heart Function. Pietsch, N., Chen, C. Y., Kupsch, S., Bacmeister, L., Geertz, B., Herrera-Rivero, M., Siebels, B., Voss, H., Kramer, E., Braren, I., Westermann, D., Schluter, H., Mearini, G., Schlossarek, S., van der Velden, J., Caporizzo, M., Lindner, D., Prosser, B. L. & Carrier, L. Circ Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39279670
IF1 is a cold-regulated switch of ATP synthase hydrolytic activity to support thermogenesis in brown fat. Brunetta, H. S., Jung, A. S., Valdivieso-Rivera, F., de Campos Zani, S. C., Guerra, J., Furino, V. O., Francisco, A., Bercot, M., Moraes-Vieira, P. M., Keipert, S., Jastroch, M., Martinez, L. O., Sponton, C. H., Castilho, R. F., Mori, M. A. & Bartelt, A. EMBO J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39284909
Thyroid Function, Diabetes, and Common Age-Related Eye Diseases: A Mendelian Randomization Study. Ellervik, C., Boulakh, L., Teumer, A., Marouli, E., Kus, A., Buch Hesgaard, H., Heegaard, S., Blankers, L., Sterenborg, R., Asvold, B. O., Winkler, T. W., Medici, M., Kjaergaard, A. D., International, A. M. D. G. C. & The Mendelian Randomization Study Group for the ThyroidOmics, C. Thyroid (2024). https://www.ncbi.nlm.nih.gov/pubmed/39283829
Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling. Keles, M., Grein, S., Froese, N., Wirth, D., Trogisch, F. A., Wardman, R., Hemanna, S., Weinzierl, N., Koch, P. S., Uhlig, S., Lomada, S., Dittrich, G. M., Szaroszyk, M., Haustein, R., Hegermann, J., Martin-Garrido, A., Bauersachs, J., Frank, D., Frey, N., Bieback, K., Cordero, J., Dobreva, G., Wieland, T. & Heineke, J. Mol Ther Nucleic Acids 35, 102306 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39281699
Association of serum zinc with mineral stress in chronic kidney disease. Sohail, A., Obereigner, J., Mitter, G., Schmid, T., Hofer, A. S., Schuster, G., Hugl, A., Dorninger, A. H., Mandl, M., Pasch, A., Lackner, H. K., Papousek, I., Dieplinger, B., Suessner, S., Antlanger, M., Cejka, D., Alesutan, I. & Voelkl, J. Clin Kidney J 17, sfae258 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39286240
Lifestyle interventions in cardiometabolic HFpEF: dietary and exercise modalities. Vacca, A., Wang, R., Nambiar, N., Capone, F., Farrelly, C., Mostafa, A., Sechi, L. A. & Schiattarella, G. G. Heart Fail Rev (2024). https://www.ncbi.nlm.nih.gov/pubmed/39283525
Development and validation of cardiometabolic risk predictive models based on LDL oxidation and candidate geromarkers from the MARK-AGE data. Valeanu, A., Margina, D., Weber, D., Stuetz, W., Moreno-Villanueva, M., Dolle, M. E. T., Jansen, E. H., Gonos, E. S., Bernhardt, J., Grubeck-Loebenstein, B., Weinberger, B., Fiegl, S., Sikora, E., Mosieniak, G., Toussaint, O., Debacq-Chainiaux, F., Capri, M., Garagnani, P., Pirazzini, C., Bacalini, M. G., Hervonen, A., Slagboom, P. E., Talbot, D., Breusing, N., Frank, J., Burkle, A., Franceschi, C., Grune, T. & Gradinaru, D. Mech Ageing Dev 222, 111987 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39284459
Distal versus proximal radial access in coronary angiography: a meta-analysis. Lueg, J., Schulze, D., Stohr, R. & Leistner, D. M. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39287659
In preprints: keeping endothelial cell specification and vascular development in check. Petzold, T. & Gerhardt, H. Development 151 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39287130
Distinct mechanisms regulate ventricular and atrial chamber wall formation. Albu, M., Affolter, E., Gentile, A., Xu, Y., Kikhi, K., Howard, S., Kuenne, C., Priya, R., Gunawan, F. & Stainier, D. Y. R. Nat Commun 15, 8159 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39289341
The gut microbiota in thrombosis. Khuu, M. P., Paeslack, N., Dremova, O., Benakis, C., Kiouptsi, K. & Reinhardt, C. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39289543
Myeloperoxidase: Reviving an old ally for immunomodulation in heart failure? Kuster, G. M., Assmus, B. & Mahfoud, F. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39290140
Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers. Liu, S., Park, T., Kruger, D. M., Pena-Centeno, T., Burkhardt, S., Schutz, A. L., Huang, Y. N., Rosewood, T., Chaudhuri, S., Cho, M., Risacher, S. L., Wan, Y., Shaw, L. M., Sananbenesi, F., Brodsky, A. S., Lin, H., Krunic, A., Blusztajn, J. K., Saykin, A. J., Delalle, I., Fischer, A., Nho, K. & Alzheimer's Disease Neuroimaging, I. Alzheimers Dement (2024). https://www.ncbi.nlm.nih.gov/pubmed/39291737
Reslice3Dto2D: Introduction of a software tool to reformat 3D volumes into reference 2D slices in cardiovascular magnetic resonance imaging. Viezzer, D., Fenski, M., Grandy, T. H., Kuhnt, J., Hadler, T., Lange, S. & Schulz-Menger, J. BMC Res Notes17, 270 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39289712
Heat and cause-specific cardiopulmonary mortality in Germany: a case-crossover study using small-area assessment. Zhang, S., Breitner, S., De' Donato, F., Stafoggia, M., Nikolaou, N., Aunan, K., Peters, A. & Schneider, A. Lancet Reg Health Eur 46, 101049 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39290807
Effect modification of air pollution on the association between heat and mortality in five European countries. Zhang, S., Breitner, S., Stafoggia, M., Donato, F. D., Samoli, E., Zafeiratou, S., Katsouyanni, K., Rao, S., Diz-Lois Palomares, A., Gasparrini, A., Masselot, P., Nikolaou, N., Aunan, K., Peters, A. & Schneider, A. Environ Res 263, 120023 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39293751
Non-HACEK gram-negative bacilli infective endocarditis: data from a retrospective German cohort study. Dorfler, J., Grubitzsch, H., Schneider-Reigbert, M., Pasic, M., Pfafflin, F., Stegemann, M., Sander, L. E., Kurth, F. & Lingscheid, T. Infection (2024). https://www.ncbi.nlm.nih.gov/pubmed/39300000
Hypertrophic obstructive cardiomyopathy-left ventricular outflow tract shapes and their hemodynamic influences applying CMR. Mayr, T., Riazy, L., Trauzeddel, R. F., Bassenge, J. P., Wiesemann, S., Blaszczyk, E., Prothmann, M., Hadler, T., Schmitter, S. & Schulz-Menger, J. Int J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/39302632
Timing of oral anticoagulation in atrial fibrillation patients after acute ischaemic stroke and outcome after 3 months: results of the multicentre Berlin Atrial Fibrillation Registry. Olma, M. C., Tutuncu, S., Hansen, K., Grittner, U., Kunze, C., Dietzel, J., Schurig, J., Dimitrijeski, B., Hagemann, G., Hamilton, F., Honermann, M., Jungehuelsing, G. J., Kauert, A., Koennecke, H. C., Mackert, B. M., Nabavi, D. G., Schmehl, I., Sparenberg, P., Stingele, R., Voelzke, E., Waldschmidt, C., Zeise-Wehry, D., Heuschmann, P. U., Endres, M. & Haeusler, K. G. Open Heart 11 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39299734
Trends in Cancer and Heart Failure related mortality in adult US population: A CDC WONDER database analysis from 1999 to 2020. Qazi, S. U., Hamid, A., Ansari, H. U. H., Khouri, M. G., Anker, M. S., Hall, M. E., Anker, S. D., Butler, J. & Khan, M. S. Am Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39299631
Bone turnover: the role of lipoproteins in a population-based study. Winckel, T., Friedrich, N., Zylla, S., Fenzlaff, M., Schopfel, J., Gauss, K. F., Petersmann, A., Nauck, M., Volzke, H. & Hannemann, A. Lipids Health Dis 23, 302 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39300501
Major depression recurrence is associated with differences in obesity-related traits in women, but not in men. Bannert, U., Siewert-Markus, U., Klinger-Konig, J., Grabe, H. J., Stracke, S., Dorr, M., Volzke, H., Markus, M. R. P., Topfer, P. & Ittermann, T. Eur Psychiatry67, e55 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39301585
Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure - a propensity score-matched study. Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G. F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W. & von Haehling, S. Diabetes Res Clin Pract, 111864 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39304136
PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates. Van Wauwe, J., Mahy, A., Craps, S., Ekhteraei-Tousi, S., Vrancaert, P., Kemps, H., Dheedene, W., Donate Puertas, R., Trenson, S., Roderick, H. L., Beerens, M. & Luttun, A. Life Sci Alliance 7 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39304345
Life-time cumulative activity burden is associated with symptomatic heart failure and arrhythmic risk in patients with arrhythmogenic right ventricular cardiomyopathy: a retrospective cohort study. Binzenhofer, L., Clauss, S., Strauss, K., Hopler, J., Kraft, M., Hoffmann, S., Brunner, S., Tomsits, P., Schuttler, D., Massberg, S., Kaab, S. & Lusebrink, E. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/39305246
Lifetime cumulative activity burden is associated with symptomatic heart failure and arrhythmic risk in patients with arrhythmogenic right ventricular cardiomyopathy: a retrospective cohort study. Binzenhofer, L., Clauss, S., Strauss, K., Hopler, J., Kraft, M., Hoffmann, S., Brunner, S., Tomsits, P., Schuttler, D., Massberg, S., Kaab, S. & Lusebrink, E. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39305246
Late diagnosis of Marfan syndrome is associated with unplanned aortic surgery and cardiovascular death. Claus, J., Schoof, L., Mir, T. S., Kammal, A. L., Schon, G., Kutsche, K., Behrendt, C. A., Kallenbach, K., Kolbel, T., Kubisch, C., Demal, T. J., Petersen, J., Brickwedel, J., Hubler, M., Detter, C., Kirchhof, P., Debus, E. S., Rybczynski, M. & von Kodolitsch, Y. J Thorac Cardiovasc Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39306029
Cardiac contractility modulation in HFrEF patients with QRS duration 120-149 ms: reduction in heart failure hospitalizations and improvement in functional outcome. Fastner, C., Varma, N., Rao, I., Falk, P., Remppis, B. A., Najarian, K., Burkhoff, D., Akin, I. & Kuschyk, J. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/39306264
Myeloid cells take ischemic insult to heart. Nicolai, L. & Massberg, S. Trends Immunol 45, 735-737 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39306560
Stool and blood metabolomics in the metabolic syndrome: a cross-sectional study. Ponce-de-Leon, M., Wang-Sattler, R., Peters, A., Rathmann, W., Grallert, H., Artati, A., Prehn, C., Adamski, J., Meisinger, C. & Linseisen, J. Metabolomics 20, 105 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39306637
Cardiac wasting in patients with cancer. Anker, M. S., Rashid, A. M., Butler, J. & Khan, M. S. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39311910
Stakeholders' Perspectives on Current Issues in Data Monitoring Committees. Cartwright, M. J., Friede, T., Lawrence, D., May, E., Mutze, T. & Roes, K. Biom J 66, e202300384 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39308116
Single-cell transcriptomics reveal distinctive patterns of fibroblast activation in heart failure with preserved ejection fraction. Lanzer, J. D., Wienecke, L. M., Ramirez Flores, R. O., Zylla, M. M., Kley, C., Hartmann, N., Sicklinger, F., Schultz, J. H., Frey, N., Saez-Rodriguez, J. & Leuschner, F. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39311911
A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation. Ma, Z., Zuo, T., Frey, N. & Rangrez, A. Y. Signal Transduct Target Ther 9, 237 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39307902
Interatrial Shunt Treatment for Heart Failure: The Randomized RELIEVE-HF Trial. Stone, G. W., Lindenfeld, J., Rodes-Cabau, J., Anker, S. D., Zile, M. R., Kar, S., Holcomb, R., Pfeiffer, M. P., Bayes-Genis, A., Bax, J. J., Bank, A. J., Costanzo, M. R., Verheye, S., Roguin, A., Filippatos, G., Nunez, J., Lee, E. C., Laufer-Perl, M., Moravsky, G., Litwin, S. E., Prihadi, E., Gada, H., Chung, E. S., Price, M. J., Thohan, V., Schewel, D., Kumar, S., Kische, S., Shah, K. S., Donovan, D. J., Zhang, Y., Eigler, N. L., Abraham, W. T. & Investigators, R.-H. Circulation150, 1931-1943 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39308371
Circulating extracellular vesicles as biomarkers in the diagnosis, prognosis and therapy of cardiovascular diseases. Bernath-Nagy, D., Kalinyaprak, M. S., Giannitsis, E., Abraham, P., Leuschner, F., Frey, N. & Krohn, J. B. Front Cardiovasc Med11, 1425159 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39314768
Optical coherence tomography characterization of degradation kinetics between second- and third-generation resorbable magnesium scaffold. Seguchi, M., Baumann-Zumstein, P., Fubel, A., Pritsch, M., Aytekin, A., Nicol, P., Altevogt, J. & Joner, M. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39314044
Updated declaration of interests for European Society of Cardiology volunteers and officers. Aguiar, C., Kirchhof, P. & Weidinger, F. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39318131
Why thorough open data descriptions matters more than ever in the age of AI: opportunities for cardiovascular research. Engelhardt, S. Eur Heart J Digit Health 5, 507-508 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39318694
Exercise training in left ventricular assist device patients: Protocol of an individual participant data meta-analysis. Kambic, T., Feuerstein, A., Tran, P. T., Friede, T., Edelmann, F., Lainscak, M. & ExTra, L. C. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39319630
Expert opinion on design and endpoints for studies on catheter ablation of atrial fibrillation. Lewalter, T., Blomstrom-Lundqvist, C., Lakkireddy, D., Packer, D., Meyer, R., Kuniss, M., Ladwig, K. H., Jilek, C., Diener, H. C., Boriani, G., Turakhia, M. P., Schneider, S., Svennberg, E., Albers, B., Andrade, J. G., de Melis, M. & Brachmann, J. J Cardiovasc Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39319521
The 129 strain-derived passenger mutations in ACKR1-deficient mice alter the expression of PYHIN and Fc-gamma receptor genes. Moller-Ramon, Z., Aslani, M., Sobczak, N., Hristov, M., Weber, C., Rot, A. & Duchene, J. J Leukoc Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39319406
Soil and water pollution and cardiovascular disease. Munzel, T., Hahad, O., Lelieveld, J., Aschner, M., Nieuwenhuijsen, M. J., Landrigan, P. J. & Daiber, A. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39317838
CITED4 gene therapy: Can it be cited for preventing maladaptive post-ischemic cardiac remodeling? Nording, H. & Muller, O. J. Mol Ther 32, 3217-3219 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39317189
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts. Ruiz-Orera, J., Miller, D. C., Greiner, J., Genehr, C., Grammatikaki, A., Blachut, S., Mbebi, J., Patone, G., Myronova, A., Adami, E., Dewani, N., Liang, N., Hummel, O., Muecke, M. B., Hildebrandt, T. B., Fritsch, G., Schrade, L., Zimmermann, W. H., Kondova, I., Diecke, S., van Heesch, S. & Hubner, N. Nat Cardiovasc Res 3, 1217-1235 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39317836
A simplified approach to discriminate between healthy subjects and patients with heart failure using cardiac magnetic resonance myocardial deformation imaging. Witt, U. E., Muller, M. L., Beyer, R. E., Wieditz, J., Salem, S., Hashemi, D., Chen, W., Cvetkovic, M., Nolden, A. C., Doeblin, P., Blum, M., Thiede, G., Huppertz, A., Steen, H., Remppis, B. A., Falk, V., Friede, T. & Kelle, S. Eur Heart J Imaging Methods Pract 2, qyae093 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39318449
MV-GNN: Generation of continuous geometric representations of mitral valve motion from 3D+t echocardiography. Ivantsits, M., Tautz, L., Huellebrand, M., Walczak, L., Akansel, S., Khasyanova, I., Kempfert, J., Sundermann, S., Falk, V. & Hennemuth, A. Comput Biol Med 182, 109154 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39321581
Associations of "Weekend Warrior" Physical Activity With Incident Disease and Cardiometabolic Health. Kany, S., Al-Alusi, M. A., Ramo, J. T., Pirruccello, J. P., Churchill, T. W., Lubitz, S. A., Maddah, M., Guseh, J. S., Ellinor, P. T. & Khurshid, S. Circulation 150, 1236-1247 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39324186
Recurrent depression predicts high leptin concentrations in patients with coronary artery disease over an 18-months follow-up period: Findings from the prospective multicenter randomized controlled SPIRR-CAD Trial. Ladwig, K. H., Marten-Mittag, B., Olliges, E., Johar, H., Atasoy, S., Holdenrieder, S., Albus, C., Deter, H. C., DeZwaan, M., Fritzsche, K., Junger, J., Petrowski, K., Michal, M., Sollner, W., Weber, C. S., Herrmann-Lingen, C. & Ronel, J. J Affect Disord (2024). https://www.ncbi.nlm.nih.gov/pubmed/39321975
Patiromer Facilitates Angiotensin Inhibitor and Mineralocorticoid Antagonist Therapies in Patients With Heart Failure and Hyperkalemia. Pitt, B., Anker, S. D., Lund, L. H., Coats, A. J. S., Filippatos, G., Rossignol, P., Weir, M. R., Friede, T., Kosiborod, M. N., Metra, M., Bohm, M., Ezekowitz, J. A., Bayes-Genis, A., Mentz, R. J., Ponikowski, P., Senni, M., Pina, I. L., Pinto, F. J., van der Meer, P., Bahit, C., Belohlavek, J., Brugts, J. J., Perrin, A., Waechter, S., Budden, J. & Butler, J. J Am Coll Cardiol 84, 1295-1308 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39322323
Impact of residual mitral regurgitation after transcatheter edge-to-edge repair in atrial functional mitral regurgitation: Results from MITRA-PRO registry. Rottlander, D., Hausleiter, J., Schmitz, T., Bufe, A., Seyfarth, M., von Bardeleben, R. S., Beucher, H., Ouarrak, T., Schneider, S., Boekstegers, P. & Investigators, M.-P. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39323306
Marmoset and human trophoblast stem cells differ in signaling requirements and recapitulate divergent modes of trophoblast invasion. Siriwardena, D., Munger, C., Penfold, C., Kohler, T. N., Weberling, A., Linneberg-Agerholm, M., Slatery, E., Ellermann, A. L., Bergmann, S., Clark, S. J., Rawlings, T. M., Brickman, J. M., Reik, W., Brosens, J. J., Zernicka-Goetz, M., Sasaki, E., Behr, R., Hollfelder, F. & Boroviak, T. E. Cell Stem Cell 31, 1427-1446 e1428 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39321797
RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth. Tetik-Elsherbiny, N., Elsherbiny, A., Setya, A., Gahn, J., Tang, Y., Gupta, P., Dou, Y., Serke, H., Wieland, T., Dubrac, A., Heineke, J., Potente, M., Cordero, J., Ola, R. & Dobreva, G. Nat Cardiovasc Res 3, 1199-1216 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39322771
A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studies. Wirbel, J., Essex, M., Forslund, S. K. & Zeller, G. Genome Biol 25, 247 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39322959
Simulation of cardiac arrhythmias in human induced pluripotent stem cell-derived cardiomyocytes. Bommer, T., Knierim, M., Unsold, J., Riedl, D., Stengel, L., Paulus, M., Kortl, T., Liaw, N., Maier, L. S., Streckfuss-Bomeke, K., Sossalla, S. & Pabel, S. PLoS One 19, e0310463 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39331676
Delivering more evidence for the specificities of heart failure with improved ejection fraction: New answers, new questions. Brandt, M., Cotter, G. & Wenzel, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39329302
The Reply. Sorensen, N. A., Fakhri, Y. & Clemmensen, P. Am J Med 137, e198-e199 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39332875
Phosphoproteomics-directed manipulation reveals SEC22B as a hepatocellular signaling node governing metabolic actions of glucagon. Wu, Y., Foollee, A., Chan, A. Y., Hille, S., Hauke, J., Challis, M. P., Johnson, J. L., Yaron, T. M., Mynard, V., Aung, O. H., Cleofe, M. A. S., Huang, C., Lim Kam Sian, T. C. C., Rahbari, M., Gallage, S., Heikenwalder, M., Cantley, L. C., Schittenhelm, R. B., Formosa, L. E., Smith, G. C., Okun, J. G., Muller, O. J., Rusu, P. M. & Rose, A. J. Nat Commun 15, 8390 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39333498
Correction to: Polygenic Risk Score: Clinically Useful Tool for Prediction of Cardiovascular Disease and Benefit from Lipid-Lowering Therapy? Arnold, N. & Koenig, W. Cardiovasc Drugs Ther 38, 1069 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39340745
Neurotoxin-Derived Optical Probes for Elucidating Molecular and Developmental Biology of Neurons and Synaptic Connections. Toxin-Derived Optical Probes for Neuroimaging. Bijjam, R., Shorter, S., Bratt, A. M., O'Leary, V. B., Ntziachristos, V. & Ovsepian, S. V. Mol Imaging Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39348040
Novel multiphoton intravital imaging enables real-time study of Helicobacter pylori interaction with neutrophils and macrophages in the mouse stomach. Ishikawa-Ankerhold, H., Busch, B., Bader, A., Maier-Begandt, D., Dionisio, F., Namineni, S., Vladymyrov, M., Harrison, U., van den Heuvel, D., Tomas, L., Walzog, B., Massberg, S., Schulz, C. & Haas, R. PLoS Pathog 20, e1012580 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39348445
Device-therapy in chronic heart failure: Cardiac contractility modulation versus cardiac resynchronization therapy. Yuecel, G., Gaasch, L., Kodeih, A., Hetjens, S., Yazdani, B., Pfleger, S., Duerschmied, D., Abraham, W. T., Akin, I. & Kuschyk, J. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39344273
August
Paper of the Month
Intramyocardial Sprouting Tip Cells Specify Coronary Arterialization
DZHK-Autor:innen: Elena Cano, Jennifer Schwarzkopf, Norbert Hübner, Holger Gerhardt
Augmentative effects of leukemia inhibitory factor reveal a critical role for TYK2 signaling in vascular calcification. Alesutan, I., Razazian, M., Luong, T. T. D., Estepa, M., Pitigala, L., Henze, L. A., Obereigner, J., Mitter, G., Zickler, D., Schuchardt, M., Deisl, C., Makridakis, M., Gollmann-Tepekoylu, C., Pasch, A., Cejka, D., Suessner, S., Antlanger, M., Bielesz, B., Muller, M., Vlahou, A., Holfeld, J., Eckardt, K. U. & Voelkl, J. Kidney Int 106, 611-624 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39084258
Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19. Essex, M., Millet Pascual-Leone, B., Lober, U., Kuhring, M., Zhang, B., Bruning, U., Fritsche-Guenther, R., Krzanowski, M., Fiocca Vernengo, F., Brumhard, S., Rowekamp, I., Anna Bielecka, A., Lesker, T. R., Wyler, E., Landthaler, M., Mantei, A., Meisel, C., Caesar, S., Thibeault, C., Corman, V. M., Marko, L., Suttorp, N., Strowig, T., Kurth, F., Sander, L. E., Li, Y., Kirwan, J. A., Forslund, S. K. & Opitz, B. NPJ Biofilms Microbiomes 10, 66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39085233
Population-based reference values for kidney function and kidney function decline in 25- to 95-year-old Germans without and with diabetes. Herold, J. M., Wiegrebe, S., Nano, J., Jung, B., Gorski, M., Thorand, B., Koenig, W., Zeller, T., Zimmermann, M. E., Burkhardt, R., Banas, B., Kuchenhoff, H., Stark, K. J., Peters, A., Boger, C. A. & Heid, I. M. Kidney Int 106, 699-711 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39084259
Cognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease: a prospective, longitudinal, multicentre study of 113 patients (CogniMOG-Study). Passoke, S., Stern, C., Haussler, V., Kumpfel, T., Havla, J., Engels, D., Jarius, S., Wildemann, B., Korporal-Kuhnke, M., Senel, M., Stellmann, J. P., Warnke, C., Grothe, M., Schulke, R., Gingele, S., Kretschmer, J. R., Klotz, L., Walter, A., Then Bergh, F., Aktas, O., Ringelstein, M., Ayzenberg, I., Schwake, C., Kleiter, I., Sperber, P. S., Rust, R., Schindler, P., Bellmann-Strobl, J., Paul, F., Kopp, B., Trebst, C., Hummert, M. W. & Neuromyelitis Optica Study, G. J Neurol Neurosurg Psychiatry (2024). https://www.ncbi.nlm.nih.gov/pubmed/39084862
Pre-hospital heparin is not associated with infarct vessel patency and mortality in ST-segment elevation myocardial infarction patients with out-of-hospital cardiac arrest. Scholz, P., Friede, T., Scholz, K. H., Grabmaier, U., Meyer, T. & Seidler, T. Clin Res Cardiol (2024). www.ncbi.nlm.nih.gov/pubmed/39088062
Intramyocardial Sprouting Tip Cells Specify Coronary Arterialization. Cano, E., Schwarzkopf, J., Kanda, M., Lindberg, E. L., Hollfinger, I., Pogontke, C., Braeuning, C., Fischer, C., Hubner, N. & Gerhardt, H. Circ Res 135, 671-684 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39092506
In vitro and in vivo optimized reconstruction for low-keV virtual monoenergetic photon-counting detector CT angiography of lower legs. Graafen, D., Bart, W., Halfmann, M. C., Muller, L., Hobohm, L., Yang, Y., Neufang, A., Espinola-Klein, C., Pitton, M. B., Kloeckner, R., Varga-Szemes, A. & Emrich, T. Eur Radiol Exp 8, 89 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39090380
Epigenetic control of metabolic identity across cell types. Pacheco, M. P., Gerard, D., Mangan, R. J., Chapman, A. R., Hecker, D., Kellis, M., Schulz, M. H., Sinkkonen, L. & Sauter, T. bioRxiv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39091778
NMDtxDB: data-driven identification and annotation of human NMD target transcripts. Britto-Borges, T., Gehring, N. H., Boehm, V. & Dieterich, C. RNA 30, 1277-1291 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39095083
Comparison of different venous access ways for right heart catheterization-a meta-analysis. Genske, F., Rawish, E., Macherey-Meyer, S., Buchel, C., Dejanovikj, M., Jurczyk, D., Schulten-Baumer, J., Marquetand, C., Stiermaier, T., Eitel, I., Rosenkranz, S., Frerker, C. & Schmidt, T. Hellenic J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39094787
Factor XI inhibitors - Rising stars in anti-thrombotic therapy? Nolte, C. H. J Neurol Sci 464, 123157 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39094433
The budget impact of implementing atrial fibrillation-screening in European countries. Eklund, M., Bernfort, L., Appelberg, K., Engler, D., Schnabel, R. B., Martinez, C., Wallenhorst, C., Boriani, G., Buckley, C. M., Diederichsen, S. Z., Svendsen, J. H., Montaner, J., Potpara, T., Levin, L. A. & Lyth, J. Eur Heart J Suppl26, iv19-iv32 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39099577
Cardiovascular magnetic resonance reveals myocardial involvement in patients with active stage of inflammatory bowel disease. Fenski, M., Abazi, E., Groschel, J., Hadler, T., Kappelmayer, D., Kolligs, F., Prieto, C., Botnar, R., Kunze, K. P. & Schulz-Menger, J. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39102000
Five-year outcomes of transcatheter aortic valve implantation with the ACURATE neo2 valve system. Mollmann, H., Noack, T., Hilker, M., Conradi, L., Toggweiler, S., Hofmann, B., Joner, M., Modolo, R., Allocco, D. J. & Kim, W. K. EuroIntervention 20, e951-e953 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39099375
Early detection of atrial fibrillation in the digital era, risk factors, treatment options, and the need for new definitions. Schnabel, R. B., Engler, D. & Freedman, B. Eur Heart J Suppl 26, iv1-iv3 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39099573
Pre-hospital admission of heparin in patients with suspected non-ST segment elevation acute coronary syndrome. Sundermeyer, J., Schock, A., Kellner, C., Haller, P. M., Lehmacher, J., Thiessen, N., Toprak, B., Scharlemann, L., Twerenbold, R., Sorensen, N. A., Clemmensen, P. & Neumann, J. T. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39102002
Pediatric reference values for myocardial contraction fraction and global function index of the left ventricle: A cardiovascular magnetic resonance study. Voges, I., Henke, B., Daubeney, P. E. F., Gabbert, D. D., Uebing, A., Pennell, D. J., Caliebe, A. & Krupickova, S. Int J Cardiol 414, 132420 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39098614
Screening for atrial fibrillation: the role of CHA(2)DS(2)-VASc and atrial fibrillation burden. Xing, L. Y., Vad, O. B., Engler, D., Svendsen, J. H. & Diederichsen, S. Z. Eur Heart J Suppl26, iv41-iv49 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39099574
Nuclear factor of activated T-cells 5 is indispensable for a balanced adaptive transcriptional response of lung endothelial cells to hypoxia. Laban, H., Siegmund, S., Schlereth, K., Trogisch, F. A., Ablieh, A., Brandenburg, L., Weigert, A., De La Torre, C., Mogler, C., Hecker, M., Kuebler, W. M. & Korff, T. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39107245
Pulmonary vein reconnection and repeat ablation characteristics following cryoballoon- compared to radiofrequency-based pulmonary vein isolation. Obergassel, J., Nies, M., Kirchhof, P. & Metzner, A. J Cardiovasc Electrophysiol 35, 2085 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39107953
Markers of Biological Brain Aging Mediate Effects of Vascular Risk Factors on Cognitive and Motor Functions: A Multivariate Imaging Analysis of 40,579 Individuals. Petersen, M., Link, M. A., Mayer, C., Nagele, F. L., Schell, M., Fiehler, J., Gallinat, J., Kuhn, S., Twerenbold, R., Omidvarnia, A., Hoffstaedter, F., Patil, K. R., Eickhoff, S. B., Thomalla, G. & Cheng, B. medRxiv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39108518
DNA-sensing inflammasomes cause recurrent atherosclerotic stroke. Cao, J., Roth, S., Zhang, S., Kopczak, A., Mami, S., Asare, Y., Georgakis, M. K., Messerer, D., Horn, A., Shemer, R., Jacqmarcq, C., Picot, A., Green, J. P., Schlegl, C., Li, X., Tomas, L., Dutsch, A., Liman, T. G., Endres, M., Wernsdorf, S. R., Furle, C., Carofiglio, O., Zhu, J., Brough, D., Group, D. S., Hornung, V., Dichgans, M., Vivien, D., Schulz, C., Dor, Y., Tiedt, S., Sager, H. B., Grosse, G. M. & Liesz, A. Nature 633, 433-441 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39112714
Breaking barriers: noncanonical inflammasome executes blood-brain barrier disruption. Dichgans, M., Neher, J. J. & Asare, Y. Signal Transduct Target Ther 9, 213 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39112463
A meta-analysis of genome-wide studies of resilience in the German population. Herrera-Rivero, M., Garvert, L., Horn, K., Lobner, M., Weitzel, E. C., Stoll, M., Lichtner, P., Teismann, H., Teumer, A., Van der Auwera, S., Volzke, H., Volker, U., Andlauer, T. F. M., Meinert, S., Heilmann-Heimbach, S., Forstner, A. J., Streit, F., Witt, S. H., Kircher, T., Dannlowski, U., Scholz, M., Riedel-Heller, S. G., Grabe, H. J., Baune, B. T. & Berger, K. Mol Psychiatry (2024). https://www.ncbi.nlm.nih.gov/pubmed/39112778
Metabolites regulating chromatin accessibility: a piece of the puzzle. Krankel, N. Eur Heart J 45, 4236-4238 (2024). www.ncbi.nlm.nih.gov/pubmed/39115023
Living with peripartum cardiomyopathy: A statement from the Heart Failure Association and the Association of Cardiovascular Nursing and Allied Professions of the European Society of Cardiology. Sliwa, K., Rakisheva, A., Viljoen, C., Pfeffer, T., Simpson, M., Jackson, A. M., Petrie, M. C., van der Meer, P., Al Farhan, H., Jovanova, S., Mbakwem, A., Sinagra, G., Van Craenenbroeck, E., Hoevelmann, J., Johnson, M. R., Mindham, R., Chioncel, O., Kahl, K. G., Rosano, G., Tschope, C., Mebazaa, A., Seferovic, P. & Bauersachs, J. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39115028
Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers-Brief Report. Witkowski, M., Wilcox, J., Province, V., Wang, Z., Nemet, I., Tang, W. H. W. & Hazen, S. L. Arterioscler Thromb Vasc Biol 44, 2136-2141 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39114916
Community-based analysis of stroke prevention and effect of public interventions in atrial fibrillation: results from the ARENA project. Zylla, M. M., Ozdemir, B., Hochadel, M., Zeymer, U., Akin, I., Grau, A., Schneider, S., Alonso, A., Waldecker, B., Suselbeck, T., Schwacke, H., Haass, M., Zahn, R., Borggrefe, M., Senges, J., Frey, N. & Thomas, D. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39115608
Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT-CHF (European) study with the ASIAN-HF registry. Cao, T. H., Tay, W. T., Jones, D. J. L., Cleland, J. G. F., Tromp, J., Emmens, J. E., Teng, T. K., Chandramouli, C., Slingsby, O. C., Anker, S. D., Dickstein, K., Filippatos, G., Lang, C. C., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Anand, I. S., Lam, C. S. P., Voors, A. A. & Ng, L. L. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39119882
Artificial intelligence in cardiovascular imaging and intervention. Engelhardt, S., Dar, S. U. H., Sharan, L., Andre, F., Nagel, E. & Thomas, S. Herz (2024). https://www.ncbi.nlm.nih.gov/pubmed/39120735
Integrated single-cell RNA-seq analysis reveals mitochondrial calcium signaling as a modulator of endothelial-to-mesenchymal transition. Lebas, M., Chinigo, G., Courmont, E., Bettaieb, L., Machmouchi, A., Goveia, J., Beatovic, A., Van Kerckhove, J., Robil, C., Angulo, F. S., Vedelago, M., Errerd, A., Treps, L., Gao, V., Delgado De la Herran, H. C., Mayeuf-Louchart, A., L'Homme, L., Chamlali, M., Dejos, C., Gouyer, V., Garikipati, V. N. S., Tomar, D., Yin, H., Fukui, H., Vinckier, S., Stolte, A., Conradi, L. C., Infanti, F., Lemonnier, L., Zeisberg, E., Luo, Y., Lin, L., Desseyn, J. L., Pickering, J., Kishore, R., Madesh, M., Dombrowicz, D., Perocchi, F., Staels, B., Pla, A. F., Gkika, D. & Cantelmo, A. R. Sci Adv 10, eadp6182 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39121218
E3 ubiquitin ligases SMURF1 and HECW1 regulate hepcidin-induced degradation of ferroportin in HeLa cells. Link, C. J., Marques, O., Knopf, J. D., Lemberg, M. K. & Muckenthaler, M. U. Biochim Biophys Acta Mol Cell Res 1871, 119803 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39117288
Left ventricular stent-graft implantation for severe left ventricular outflow tract obstruction after transcatheter mitral valve implantation. Ruge, H. & Krane, M. Eur J Cardiothorac Surg 66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39120113
Fetal growth restriction induced by maternal gal-3 deficiency is associated with altered gut-placenta axis. Xie, Y., Zhao, F., Wang, Y., Borowski, S., Freitag, N., Tirado-Gonzalez, I., Hofsink, N., Matschl, U., Plosch, T., Garcia, M. G. & Blois, S. M. Cell Death Dis 15, 575 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39117607
The many facets of TMEM63/OCaR proteins as mechanosensitive channels in lysosomes, NAADP signaling and beyond. Freichel, M., Tsvilovskyy, V., Philippaert, K., Schulte, U. & Ottenheijm, R. Cell Calcium 123, 102942 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39121527
Failure of Surgical Aortic Valve Prostheses: An Analysis of Heart Team Decisions and Postoperative Outcomes. Schnackenburg, P., Saha, S., Ali, A., Horke, K. M., Buech, J., Mueller, C. S., Sadoni, S., Orban, M., Kaiser, R., Doldi, P. M., Rizas, K., Massberg, S., Hagl, C. & Joskowiak, D. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39124728
A Randomized Comparison of the Treatment Sequence of Percutaneous Coronary Intervention and Transcatheter Aortic Valve Implantation: Rationale and Design of the TAVI PCI Trial. Stahli, B. E., Linke, A., Westermann, D., Van Mieghem, N. M., Leistner, D. M., Massberg, S., Alber, H., Mugge, A., Musumeci, G., Kesterke, R., Schneider, S., Kastrati, A., Ford, I., Ruschitzka, F., Kasel, M. A. & Investigators, T. P. Am Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39121916
The Efficiency of In Vitro Differentiation of Primate iPSCs into Cardiomyocytes Depending on Their Cell Seeding Density and Cell Line Specificity. Tereshchenko, Y., Petkov, S. G. & Behr, R. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39126016
Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard. Egea, V., Lutterberg, K., Steinritz, D., Rothmiller, S., Steinestel, K., Caca, J., Nerlich, A., Blum, H., Reschke, S., Khani, S., Bartelt, A., Worek, F., Thiermann, H., Weber, C. & Ries, C. Cell Death Dis 15, 585 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39127703
Impact of training data composition on the generalizability of CNN aortic cross section segmentation in 4D Flow MRI. Manini, C., Hullebrand, M., Walczak, L., Nordmeyer, S., Jarmatz, L., Kuehne, T., Stern, H., Meierhofer, C., Harloff, A., Erley, J., Kelle, S., Bannas, P., Trauzeddel, R. F., Schulz-Menger, J. & Hennemuth, A. J Cardiovasc Magn Reson, 101081 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39127260
Unique brain injury patterns after proton vs photon radiotherapy for WHO grade 2-3 gliomas. Winter, S. F., Gardner, M. M., Karschnia, P., Vaios, E. J., Grassberger, C., Bussiere, M. R., Nikolic, K., Pongpitakmetha, T., Ehret, F., Kaul, D., Boehmerle, W., Endres, M., Shih, H. A., Parsons, M. W. & Dietrich, J. Oncologist 29, e1748-e1761 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39126664
Sarcopenia influences usage of reperfusion treatment in patients with pulmonary embolism aged 75 years and older. Keller, K., Schmitt, V. H., Brochhausen, C., Hahad, O., Engelhardt, M., Espinola-Klein, C., Munzel, T., Lurz, P., Konstantinides, S. & Hobohm, L. Int J Cardiol Heart Vasc 53, 101470 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39132305
Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation. Kim, R., Nagel, S. H., Liaw, N. Y., Zimmermann, W. H., Zelarayan, L. C. & Schoger, E. Stem Cell Res 80, 103531 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39128210
The DanGer Shock trial: a new dawn but much to uncover. Lusebrink, E., Binzenhofer, L. & Thiele, H. Eur Heart J 45, 4181-4183 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39132927
PITX2 deficiency leads to atrial mitochondrial dysfunction. Reyat, J. S., Sommerfeld, L. C., O'Reilly, M., Cardoso, V. R., Thiemann, E., Khan, A. O., O'Shea, C., Harder, S., Muller, C., Barlow, J., Stapley, R. J., Chua, W., Kabir, S. N., Grech, O., Hummel, O., Hubner, N., Kaab, S., Mont, L., Hatem, S. N., Winters, J., Zeemering, S., Morgan, N. V., Rayes, J., Gehmlich, K., Stoll, M., Brand, T., Schweizer, M., Piasecki, A., Schotten, U., Gkoutos, G. V., Lorenz, K., Cuello, F., Kirchhof, P. & Fabritz, L. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39129206
Heart rate reactivity, recovery, and endurance of the incremental shuttle walk test in patients prone to heart failure. Wei, F. F., Mariottoni, B., An, D. W., Pellicori, P., Yu, Y. L., Verdonschot, J. A. J., Liu, C., Ahmed, F. Z., Petutschnigg, J., Rossignol, P., Heymans, S., Cuthbert, J., Girerd, N., Li, Y., Clark, A. L., Nawrot, T. S., Ferreira, J. P., Zannad, F., Cleland, J. G. F., Staessen, J. A. & investigators, H. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39129059
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Aich, A., Boshnakovska, A., Witte, S., Gall, T., Unthan-Fechner, K., Yousefi, R., Chowdhury, A., Dahal, D., Methi, A., Kaufmann, S., Silbern, I., Prochazka, J., Nichtova, Z., Palkova, M., Raishbrook, M., Koubkova, G., Sedlacek, R., Troder, S. E., Zevnik, B., Riedel, D., Michanski, S., Mobius, W., Strobel, P., Luchtenborg, C., Giavalisco, P., Urlaub, H., Fischer, A., Brugger, B., Jakobs, S. & Rehling, P. Nat Commun 15, 6914 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39134548
PAK3 Exacerbates Cardiac Lipotoxicity via SREBP1c in Obesity Cardiomyopathy. Chen, X., Ruiz-Velasco, A., Zou, Z., Hille, S. S., Ross, C., Fonseka, O., Gare, S. R., Alatawi, N. H. O., Raja, R., Zhang, J., Kaur, N., Zhao, X., Morrell-Davies, H., Miller, J. M., Abouleisa, R. R. E., Ou, Q., Frank, D., Rutter, M. K., Pinali, C., Wang, T., Mohamed, T. M. A., Muller, O. J. & Liu, W. Diabetes (2024). https://www.ncbi.nlm.nih.gov/pubmed/39137120
Integrating multiple kidney function markers to predict all-cause and cardiovascular disease mortality: prospective analysis of 366 758 UK Biobank participants. Fujii, R., Melotti, R., Kottgen, A., Teumer, A., Giardiello, D. & Pattaro, C. Clin Kidney J17, sfae207 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39135936
Burden of Heart Failure in Patients With Tricuspid Regurgitation and Effect of Transcatheter Repair on Different Subdimensions of Quality of Life. Stocker, T. J., Sommer, S., Cohen, D. J., Spertus, J. A., Stolz, L., Doldi, P. M., Weckbach, L. T., Nabauer, M., Massberg, S. & Hausleiter, J. J Am Heart Assoc 13, e034112 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39136306
Association of adverse pregnancy outcomes with cardiovascular risk profiles in later life: Current insights from the Hamburg City Health Study (HCHS). Unger, E., Makarova, N., Borof, K., Schlieker, P., Reinbold, C. V., Aarabi, G., Blankenberg, S., Magnussen, C., Behrendt, C. A., Zyriax, B. C. & Schnabel, R. B. Atherosclerosis396, 118526 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39133970
Telemedical management of symptomatic COVID-19 outpatients. von Falkenhausen, A. S., Geipel, S., Gail, A., Scherer, C., Stockhausen, S., Sams, L. E., Becker, F., Doldi, P. M., Lemmermohle, E., de Villele, P., Schleef, M., Becker, M., Lauterbach, M., Massberg, S., Kaab, S. & Sinner, M. F. ERJ Open Res 10 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39135664
Amplification of autoimmune organ damage by NKp46-activated ILC1. Biniaris-Georgallis, S. I., Aschman, T., Stergioula, K., Schreiber, F., Jafari, V., Taranko, A., Karmalkar, T., Kasapi, A., Lenac Rovis, T., Jelencic, V., Bejarano, D. A., Fabry, L., Papacharalampous, M., Mattiola, I., Molgora, M., Hou, J., Hublitz, K. W., Heinrich, F., Guerra, G. M., Durek, P., Patone, G., Lindberg, E. L., Maatz, H., Holsken, O., Kronke, G., Mortha, A., Voll, R. E., Clarke, A. J., Hauser, A. E., Colonna, M., Thurley, K., Schlitzer, A., Schneider, C., Stamatiades, E. G., Mashreghi, M. F., Jonjic, S., Hubner, N., Diefenbach, A., Kanda, M. & Triantafyllopoulou, A. Nature (2024). https://www.ncbi.nlm.nih.gov/pubmed/39137897
High-density multipolar mapping facilitating ablation of atypical atrial flutter: the power of 'more mapping less ablation'. Heeger, C. H., Feher, M., Vogler, J. & Tilz, R. R. Eur Heart J Case Rep 8, ytae369 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39139855
Determining sensitivity and specificity of risk scores for QTc interval prolongation in hemato-oncology patients prescribed systemic antifungal therapy: a retrospective cross-sectional study. Steinbrech, J., Klein, T., Kirschke, S., Mannell, H., Clauss, S., Bertsche, T. & Strobach, D. Int J Clin Pharm (2024). https://www.ncbi.nlm.nih.gov/pubmed/39141182
Combined Surgical and Percutaneous Management of Circumflex Artery Occlusion After Minimally Invasive Mitral Valve Repair. Hinkov, H., Greve, D., Lee, C. B., Klein, C., Dreysse, S., Kukucka, M., Akansel, S., Falk, V., Kofler, M. & Kempfert, J. J Am Coll Cardiol 84, 766-770 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39142732
Targeting HFpEF: Unlocking the Potential of Glucagon Receptor Blockade. Santiago Padilla, L. & Schiattarella, G. G. Circ Res 135, 629-631 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39146397
The effectiveness of coronary computed tomography angiography and functional testing for the diagnosis of obstructive coronary artery disease: results from the individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT). Schlattmann, P., Wieske, V., Bressem, K. K., Gotz, T., Schuetz, G. M., Andreini, D., Pontone, G., Alkadhi, H., Hausleiter, J., Zimmermann, E., Gerber, B., Shabestari, A. A., Meijs, M. F. L., Sato, A., Ovrehus, K. A., Jenkins, S. M. M., Knuuti, J., Hamdan, A., Halvorsen, B. A., Mendoza-Rodriguez, V., Rixe, J., Wan, Y. L., Langer, C., Leschka, S., Martuscelli, E., Ghostine, S., Tardif, J. C., Sanchez, A. R., Haase, R. & Dewey, M. Insights Imaging 15, 208 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39143443
Association of Cardiac MRI-derived Aortic Stiffness with Early Stages and Progression of Heart Failure with Preserved Ejection Fraction. Schulz, A., Schellinger, I. N., Backhaus, S. J., Adler, A. S., Lange, T., Evertz, R., Kowallick, J. T., Hoffmann, A., Matek, C., Tsao, P. S., Hasenfuss, G., Raaz, U. & Schuster, A. Radiol Cardiothorac Imaging 6, e230344 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39145733
Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism-related vascular thrombosis with microvascular injury and its consequences. Zhao, D., Han, C., Mammadova-Bach, E., Watanabe-Kusunoki, K., Bandeira Honda, T. S., Li, Y., Li, C., Li, Q., Long, H., Lyubenov, L., Shi, C., Santovito, D., Weber, C., Boor, P., Droste, P., Parikh, S., Shapiro, J., De Chiara, L., Carangelo, G., Romagnani, P., Klussmann, S., Vater, A. & Anders, H. J. Kidney Int (2024). https://www.ncbi.nlm.nih.gov/pubmed/39142565
The calcium-sensing-receptor (CaSR) in adipocytes contributes to sex-differences in the susceptibility to high fat diet induced obesity and atherosclerosis. Adam, S., Maas, S. L., Huchzermeier, R., Rakateli, L., Abschlag, K., Hohl, M., Liao, L., Bartneck, M., Teunissen, M., Wouters, K., Santovito, D., Jankowski, J., Biessen, E. A. L. & van der Vorst, E. P. C. EBioMedicine 107, 105293 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39146692
Unravelling the complexity of heart failure with preserved ejection fraction and secondary mitral regurgitation. Doldi, P. M., Stolz, L. & Hausleiter, J. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39148248
Converting PROMIS((R))-29 v2.0 profile data to SF-36 physical and mental component summary scores in patients with cardiovascular disorders. Liegl, G., F, H. F., C, N. M., Ronnefarth, M., Blumrich, A., Ahmadi, M., Boldt, L. H., Eckardt, K. U., Endres, M., Edelmann, F., Gerhardt, H., Grittner, U., Haghikia, A., Hubner, N., Landmesser, U., Leistner, D., Mai, K., Kollmus-Heege, J., D, N. M., C, H. N., S, K. P., K, M. S.-O., Pischon, T., Rattan, S., Rohrpasser-Napierkowski, I., Schonrath, K., Schulz-Menger, J., Schweizerhof, O., Spranger, J., J, E. W., Witzenrath, M., Schmidt, S. & Rose, M. Health Qual Life Outcomes 22, 64 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39148105
Therapeutic Spp1 silencing in TREM2(+) cardiac macrophages suppresses atrial fibrillation. Momin, N., Pabel, S., Rudra, A., Kumowski, N., Lee, I. H., Mentkowski, K., Yamazoe, M., Stengel, L., Muse, C. G., Seung, H., Paccalet, A., Gonzalez-Correa, C., Jacobs, E. B., Grune, J., Schloss, M. J., Sossalla, S., Wojtkiewicz, G., Iwamoto, Y., McMullen, P., Mitchell, R. N., Ellinor, P. T., Anderson, D. G., Naxerova, K., Nahrendorf, M. & Hulsmans, M. bioRxiv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39149373
Hypothermic oxygenated perfusion of the donor heart in heart transplantation: the short-term outcome from a randomised, controlled, open-label, multicentre clinical trial. Rega, F., Lebreton, G., Para, M., Michel, S., Schramm, R., Begot, E., Vandendriessche, K., Kamla, C., Gerosa, G., Berman, M., Boeken, U., Clark, S., Ranasinghe, A., Ius, F., Forteza, A., Pivodic, A., Hennig, F., Guenther, S., Zuckermann, A., Knosalla, C., Dellgren, G., Wallinder, A. & investigators, N. Lancet 404, 670-682 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39153817
High serum prevalence of autoreactive IgG antibodies against peripheral nerve structures in patients with neurological post-COVID-19 vaccination syndrome. Arlt, F. A., Breuer, A., Trampenau, E., Boesl, F., Kirchner, M., Mertins, P., Sanchez-Sendin, E., Nasouti, M., Mayrhofer, M., Bluthner, M., Endres, M., Pruss, H. & Franke, C. Front Immunol 15, 1404800 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39156891
Favorable safety profile of NOAC therapy in patients after tricuspid transcatheter edge-to-edge repair. Hoerbrand, I. A., Kraus, M. J., Gruber, M., Geis, N. A., Schlegel, P., Frey, N. & Konstandin, M. H. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39158599
Efficacy of four different left atrial appendage closure techniques during cardiac surgery-A transesophageal echocardiography follow-up study. Petersen, J., Boning, H., Yildirim, S., Alassar, Y., Yildirim, Y., Bazhanov, I., Sinning, C., Reichenspurner, H. & Pecha, S. JTCVS Tech 26, 43-49 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39156535
Differences in impact of current and former shift work on cardiovascular risk factors, carotid atherosclerosis, and white matter integrity. Rimmele, D. L., Petersen, E. L., Affolderbach, S., Petersen, M., Cheng, B., Mayer, C., Nagele, F. L., Harth, V., Terschuren, C., Kuhn, S., Zeller, T., Gerloff, C. & Thomalla, G. Sleep Adv 5, zpae056 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39156216
Beyond the Heartbeat: Single-Cell Omics Redefining Cardiovascular Research. Seeler, S., Arnarsson, K., Dressen, M., Krane, M. & Doppler, S. A. Curr Cardiol Rep (2024). https://www.ncbi.nlm.nih.gov/pubmed/39158785
Editorial to: Efficacy and safety of a novel temperature-controlled catheter for cavotricuspid isthmus ablation. Alagjozovski, H. & Heeger, C. H. J Cardiovasc Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39161049
Pro-adrenomedullin associates with congestion in acute heart failure patients. Beer, B. N., Keshtkaran, S., Kellner, C., Besch, L., Sundermeyer, J., Dettling, A., Kirchhof, P., Blankenberg, S., Magnussen, C. & Schrage, B. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39161275
A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes. Halama, A., Zaghlool, S., Thareja, G., Kader, S., Al Muftah, W., Mook-Kanamori, M., Sarwath, H., Mohamoud, Y. A., Stephan, N., Ameling, S., Pucic Bakovic, M., Krumsiek, J., Prehn, C., Adamski, J., Schwenk, J. M., Friedrich, N., Volker, U., Wuhrer, M., Lauc, G., Najafi-Shoushtari, S. H., Malek, J. A., Graumann, J., Mook-Kanamori, D., Schmidt, F. & Suhre, K. Nat Commun 15, 7111 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39160153
Beyond the snapshot: harnessing daily physical activity for heart failure characterization. Assmus, B. & Bauer, P. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39167192
RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening. Ghosh, S., Nguyen, M. T., Choi, H. E., Stahl, M., Kuhn, A. L., Van der Auwera, S., Grabe, H. J., Volzke, H., Homuth, G., Myers, S. A., Hogaboam, C. M., Noth, I., Martinez, F. J., Petsko, G. A. & Glimcher, L. H. Nat Commun 15, 7138 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39164231
On the Application of Artificial Intelligence/Machine Learning (AI/ML) in Late-Stage Clinical Development. Kochert, K., Friede, T., Kunz, M., Pang, H., Zhou, Y. & Rantou, E. Ther Innov Regul Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/39167298
Pulsed-field vs. cryoballoon-based pulmonary vein isolation: Lessons from repeat procedures. Lemoine, M. D., Obergassel, J., Jaeckle, S., Nies, M., Taraba, S., Mencke, C., Riess, J., My, I., Rottner, L., Moser, F., Ismaili, D., Reissmann, B., Ouyang, F., Kirchhof, P., Rillig, A. & Metzner, A. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/39166530
Pulsed-field- vs. cryoballoon-based pulmonary vein isolation: lessons from repeat procedures. Lemoine, M. D., Obergassel, J., Jaeckle, S., Nies, M., Taraba, S., Mencke, C., Riess, J., My, I., Rottner, L., Moser, F., Ismaili, D., Reissmann, B., Ouyang, F., Kirchhof, P., Rillig, A. & Metzner, A. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39166530
Characteristic calcification behavior of five surgical aortic valve bioprostheses models: An in vitro study. Sadat, N., Lojenburg, J. H., Scharfschwerdt, M., Klinger, M., Fujita, B. & Ensminger, S. Health Sci Rep 7, e2304 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39166121
[Practical guidance for the implantation of non-transvenous ICD systems]. Duncker, D., Albert, K., Rillig, A., Sommer, P., Heeger, C. H., Gunawardene, M., Rolf, S., Jansen, H., Estner, H., Althoff, T., Maurer, T., Tilz, R., Iden, L., Johnson, V. & Steven, D. Herzschrittmacherther Elektrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39168897
Nocturnal Cardiac Arrhythmias in Heart Failure with Obstructive and Central Sleep Apnea. Horvath, C. M., Fisser, C., Floras, J. S., Sossalla, S., Wang, S., Tomlinson, G., Rankin, F., Yatsu, S., Ryan, C. M., Bradley, T. D., Arzt, M. & Investigators, A.-H. Chest (2024). https://www.ncbi.nlm.nih.gov/pubmed/39168180
Survey on the knowledge and practices in anorexia of aging diagnosis and management in Japan. Takagi, S., Satake, S., Sugimoto, K., Kuzuya, M., Akishita, M., Arai, H., Aprahamian, I., Coats, A. J., Klompenhouwer, T., Anker, S. D. & Wakabayashi, H. J Cachexia Sarcopenia Muscle 15, 2164-2174 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39169516
Interoperable Integration of Automatic ECG Processing Using DICOMweb and the AcuWave Software Suite. Graf, L., Krefting, D., Kesztyus, T., Oremek, M., Zenker, S. & Spicher, N. Stud Health Technol Inform 316, 1401-1405 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39176642
[Integration of Inventory Data from Cohort and Registry Studies into an Existing Research Network: National Pandemic Cohort Network (NAPKON)]. Hofmann, A. L., Vehreschild, J. J., Witzenrath, M., Hoffmann, W., Illig, T., Schreiber, S., Anton, G., Hellmuth, J. C., Muenchhoff, M., Scherer, C., Pley, C., Thibeault, C., Kurth, F., Berger, S., Hummel, M., Hopff, S. M., Stecher, M., Appel, K., Stahl, D., Kraus, M., Lorenz-Depiereux, B., Hanss, S., von Kielmansegg, S., Schlunder, I., Niemeyer, A., Heuschmann, P., Krawczak, M. & Reese, J. P. Gesundheitswesen (2024). https://www.ncbi.nlm.nih.gov/pubmed/39173676
Implementation of an Atrioventricular Valve Intervention Registry: Comparative Study of REDCap vs. CDR-Based openEHR Registry. Kinast, B., Rohde, H., Anywar, M., Bronsch, T., Voran, J., Kreidl, F., Frank, D. & Schreiweis, B. Stud Health Technol Inform316, 1069-1073 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39176974
Serum concentrations of levosimendan and its metabolites OR-1855 and OR-1896 in cardiac surgery patients with cardiopulmonary bypass. Kipka, H., Liebchen, U., Hubner, M., Hofner, G., Frey, O., Wanner, K. T., Kilger, E., Hagl, C., Tomasi, R. & Mannell, H. Front Cardiovasc Med 11, 1406338 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39175630
Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Lisowski, P., Lickfett, S., Rybak-Wolf, A., Menacho, C., Le, S., Pentimalli, T. M., Notopoulou, S., Dykstra, W., Oehler, D., Lopez-Calcerrada, S., Mlody, B., Otto, M., Wu, H., Richter, Y., Roth, P., Anand, R., Kulka, L. A. M., Meierhofer, D., Glazar, P., Legnini, I., Telugu, N. S., Hahn, T., Neuendorf, N., Miller, D. C., Boddrich, A., Polzin, A., Mayatepek, E., Diecke, S., Olzscha, H., Kirstein, J., Ugalde, C., Petrakis, S., Cambridge, S., Rajewsky, N., Kuhn, R., Wanker, E. E., Priller, J., Metzger, J. J. & Prigione, A. Nat Commun 15, 7027 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39174523
UV light exposure vs. vitamin D supplementation: a comparison of health benefits and vitamin D metabolism in a pig model. Kuhn, J., Brandsch, C., Bailer, A. C., Kiourtzidis, M., Hirche, F., Yu Chen, C., Marko, L., Bartolomaeus, T. U. P., Lober, U., Michel, S., Wensch-Dorendorf, M., Forslund-Startceva, S. K. & Stangl, G. I. J Nutr Biochem, 109746 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39178919
Change of self-rated physical health predicts mortality in aging individuals: results of a population-based cohort study. Reinwarth, A. C., Wicke, F. S., Ruckert, K. K., Schattenberg, J. M., Tuscher, O., Wild, P. S., Munzel, T., Konig, J., Lackner, K. J., Pfeiffer, N. & Beutel, M. E. Arch Public Health 82, 130 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39180092
Prevalence of current suicidal thoughts and lifetime suicide attempts in individuals with cancer and other chronic diseases in Germany: Evidence for differential associations from a representative community cohort. Schwinn, T., Paul, R. H., Hirschmiller, J., Brahler, E., Wiltink, J., Zwerenz, R., O'Connor, R. C., Wild, P. S., Munzel, T., Konig, J., Geschke, K., Moehler, M., Konstantinides, S., Justenhoven, C., Lackner, K. J., Pfeiffer, N., Beutel, M. E. & Ernst, M. J Affect Disord367, 193-201 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39178957
Heart brain axis in health and disease: role of innate and adaptive immunity. Simats, A., Sager, H. & Liesz, A. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39180327
Echocardiographic assessment of atrial, ventricular, and valvular function in patients with atrial fibrillation-an expert proposal by the german working group of cardiovascular ultrasound. Hagendorff, A., Stobe, S., Helfen, A., Knebel, F., Altiok, E., Beckmann, S., Bekfani, T., Binder, T., Ewers, A., Hamadanchi, A., Ten Freyhaus, H., Groscheck, T., Haghi, D., Knierim, J., Kruck, S., Lenk, K., Merke, N., Pfeiffer, D., Dorta, E. R., Ruf, T., Sinning, C., Wunderlich, N. C., Brandt, R. & Ewen, S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39186180
Ferric carboxymaltose and exercise capacity in heart failure with preserved ejection fraction and iron deficiency: the FAIR-HFpEF trial. von Haehling, S., Doehner, W., Evertz, R., Garfias-Veitl, T., Derad, C., Diek, M., Karakas, M., Birkemeyer, R., Fillippatos, G., Lainscak, M., Butler, J., Ponikowski, P., Bohm, M., Friede, T. & Anker, S. D. Eur Heart J 45, 3789-3800 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39185895
Mitral regurgitation evolution after transcatheter tricuspid valve interventions - a sub-analysis of the TriValve Registry. Cannata, F., Sticchi, A., Russo, G., Stankowski, K., Hahn, R. T., Alessandrini, H., Andreas, M., Braun, D., Connelly, K. A., Denti, P., Estevez-Loureiro, R., Fam, N., Harr, C., Hausleiter, J., Himbert, D., Kalbacher, D., Adamo, M., Latib, A., Lubos, E., Ludwig, S., Lurz, P., Monivas, V., Nickenig, G., Pedrazzini, G., Pozzoli, A., Praz, F., Rodes-Cabau, J., Rommel, K. P., Schofer, J., Sievert, H., Tang, G., Thiele, H., Kresoja, K. P., Metra, M., Stephan von Bardeleben, R., Webb, J., Windecker, S., Leon, M., Maisano, F., De Marco, F., Pontone, G. & Taramasso, M. Eur Heart J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/39189600
Anticoagulation in Patients With Device-Detected Atrial Fibrillation With and Without a Prior Stroke or Transient Ischemic Attack: The NOAH-AFNET 6 Trial. Diener, H. C., Becher, N., Sehner, S., Toennis, T., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Beuger, V., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G. A., Dichtl, W., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A., Lip, G. Y. H., Lubinski, A., Marijon, E., Merkely, B., Mont, L., Nikorowitsch, J., Ozga, A. K., Rajappan, K., Sarkozy, A., Scherr, D., Schnabel, R. B., Schotten, U., Simantirakis, E., Vardas, P., Wichterle, D., Zapf, A., Kirchhof, P. & investigators, N.-A. J Am Heart Assoc 13, e036429 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39190564
Contemporary trends of atrial fibrillation management in heart failure patients: Do we practice what we preach? Fink, T., Sciacca, V., Kirchhof, P. & Sommer, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39189847
Symmetric Dimethylarginine Predicts Previously Undetected Atrial Fibrillation in Patients With Ischemic Stroke. Hannemann, J., Wasser, K., Mileva, Y., Kleinsang, F., Schubert, M., Schwedhelm, E., Guan, K., Wachter, R. & Boger, R. J Am Heart Assoc 13, e034994 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39190577
Congress wrap-up: ESC Preventive Cardiology 2024 in Athens. Krankel, N., Claessen, G., Abreu, A. & Papadakis, M. Eur Heart J 45, 3785-3786 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39190608
Public attitudes towards personal health data sharing in long-term epidemiological research: a Citizen Science approach in the KORA study. Ruckert-Eheberg, I. M., Heier, M., Simon, M., Kraus, M., Peters, A. & Linkohr, B. BMC Public Health 24, 2317 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39187842
Application of the American College of Cardiology's Clinical Decision Pathway for Patients With Acute Chest Pain Using a Real-World Cohort. Thiessen, N., Kellner, C., Haller, P. M., Lehmacher, J., Schock, A., Toprak, B., Twerenbold, R., Sorensen, N. A. & Neumann, J. T. J Am Heart Assoc 13, e036096 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39189617
Echocardiographic assessment of left atrial appendage morphology and function-an expert proposal by the German Working Group of Cardiovascular Ultrasound. Hagendorff, A., Stobe, S., Helfen, A., Knebel, F., Altiok, E., Beckmann, S., Bekfani, T., Binder, T., Ewers, A., Hamadanchi, A., Freyhaus, H. T., Groscheck, T., Haghi, D., Knierim, J., Kruck, S., Lenk, K., Merke, N., Pfeiffer, D., Dorta, E. R., Ruf, T., Sinning, C., Wunderlich, N. C., Brandt, R. & Ewen, S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39196343
The right heart in patients with cancer. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Council of Cardio-Oncology. Keramida, K., Farmakis, D., Rakisheva, A., Tocchetti, C. G., Ameri, P., Asteggiano, R., Barac, A., Bax, J., Bayes-Genis, A., Bergler Klein, J., Bucciarelli-Ducci, C., Celutkiene, J., Coats, A. J. S., Cohen Solal, A., Dent, S., Filippatos, G., Ghosh, A., Hermann, J., Koop, Y., Lenihan, D., Lopez Fernandez, T., Lyon, A. R., Mercurio, V., Moura, B., Piepoli, M., Sener, Y. Z., Suter, T., Sverdlov, A. L., Tadic, M., Thum, T., van der Meer, P., van Linthout, S., Metra, M. & Rosano, G. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39193837
Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response. Rath, S. K., Nyamsuren, G., Tampe, B., Yu, D. S., Hulshoff, M. S., Schlosser, D., Maamari, S., Zeisberg, M. & Zeisberg, E. M. Clin Epigenetics 16, 119 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39192299
Optical coherence tomography predictors of clinical outcomes after stent implantation: the ILUMIEN IV trial. Landmesser, U., Ali, Z. A., Maehara, A., Matsumura, M., Shlofmitz, R. A., Guagliumi, G., Price, M. J., Hill, J. M., Akasaka, T., Prati, F., Bezerra, H. G., Wijns, W., Leistner, D., Canova, P., Alfonso, F., Fabbiocchi, F., Calligaris, G., Oemrawsingh, R. M., Achenbach, S., Trani, C., Singh, B., McGreevy, R. J., McNutt, R. W., Ying, S. W., Buccola, J. & Stone, G. W. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39196989
Outcomes of 576 patients with extracorporeal life support for the treatment of perioperative cardiogenic shock. Aboud, A., Huting, F., Fujita, B., Zittermann, A., Al-Khalil, R., Puehler, T., Ensminger, S. & Gummert, J. Interdiscip Cardiovasc Thorac Surg 39 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39208291
Malondialdehyde-specific natural IgM inhibit NETosis triggered by coronary extracellular vesicles of myocardial infarction patients. Gerhardt, T. & Landmesser, U. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39215572
Rare coding variant analysis for human diseases across biobanks and ancestries. Jurgens, S. J., Wang, X., Choi, S. H., Weng, L. C., Koyama, S., Pirruccello, J. P., Nguyen, T., Smadbeck, P., Jang, D., Chaffin, M., Walsh, R., Roselli, C., Elliott, A. L., Wijdeveld, L., Biddinger, K. J., Kany, S., Ramo, J. T., Natarajan, P., Aragam, K. G., Flannick, J., Burtt, N. P., Bezzina, C. R., Lubitz, S. A., Lunetta, K. L. & Ellinor, P. T. Nat Genet 56, 1811-1820 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39210047
Myocardial fibrosis from the perspective of the extracellular matrix: mechanisms to clinical impact. Lunde, I. G., Rypdal, K. B., Van Linthout, S., Diez, J. & Gonzalez, A. Matrix Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39214156
Predictors of residual tricuspid regurgitation after interventional therapy: an automated deep-learning CT analysis. Mattig, I., Romero Dorta, E., Fitch, K., Lembcke, A., Dewey, M., Stangl, K. & Dreger, H. Sci Rep 14, 19946 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39198524
Association between caseload volume and outcomes in left ventricular assist device implantations - a EUROMACS analysis. Mihalj, M., Reineke, D., Just, I. A., Mulzer, J., Cholevas, N., Hoermandinger, C., Veen, K., Luedi, M. M., Heinisch, P. P., Potapov, E., Gummert, J. F., Mohacsi, P., Hagl, C., Faerber, G., Zimpfer, D., de By, T., Meyns, B., Gustafsson, F., Hunziker, L., Siepe, M., Schober, P. & Schoenrath, F. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39206731
Potassium channel TASK-5 forms functional heterodimers with TASK-1 and TASK-3 to break its silence. Rinne, S., Schick, F., Vowinkel, K., Schutte, S., Krasel, C., Kauferstein, S., Schafer, M. K., Kiper, A. K., Muller, T. & Decher, N. Nat Commun 15, 7548 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39215006
Catheter Ablation in Patients with End-Stage Heart Failure and Atrial Fibrillation: Two-year Follow-up of the CASTLE-HTx Trial. Sohns, C., Moersdorf, M., Marrouche, N. F., Bergau, L., Costard-Jaeckle, A., Crijns, H., Fox, H., Hindricks, G., Dagres, N., Sossalla, S., Schramm, R., Fink, T., El Hamriti, M., Sciacca, V., Didenko, M., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., Sommer, P. & Investigators, C. H. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39213004
Transjugular Transcatheter Tricuspid Valve Replacement: Early Compassionate Use Outcomes. Stolz, L., Cheung, A., Boone, R., Fam, N., Ong, G., Villablanca, P., Jabri, A., De Backer, O., Molller, J. E., Tchetche, D., Oliva, O., Chak-Yu So, K., Lam, Y. Y., Latib, A., Scotti, A., Coisne, A., Sudre, A., Dreyfus, J., Nejjari, M., Favre, P. E., Cruz-Gonzalez, I., Estevez-Loureiro, R., Barreiro-Perez, M., Makkar, R., Patel, D., Leurent, G., Donal, E., Modine, T. & Hausleiter, J. JACC Cardiovasc Interv 17, 1936-1945 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39197992
Systems Biology Approach Uncovers Candidates for Liver-Heart Interorgan Crosstalk in HFpEF. Strocchi, S., Liu, L., Wang, R., Haseli, S. P., Capone, F., Bode, D., Nambiar, N., Eroglu, T., Santiago Padilla, L., Farrelly, C., Vacca, A., Mascagni, M., Oeing, C. U., Kintscher, U., Jung, S., Diezel, S. A., Lievano Contreras, S. V., Zhou, M., Seldin, M. & Schiattarella, G. G. Circ Res 135, 873-876 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39206552
Diagnostic accuracy of a machine learning algorithm using point-of-care high-sensitivity cardiac troponin I for rapid rule-out of myocardial infarction: a retrospective study. Toprak, B., Solleder, H., Di Carluccio, E., Greenslade, J. H., Parsonage, W. A., Schulz, K., Cullen, L., Apple, F. S., Ziegler, A., Blankenberg, S. & Artificial Intelligence in Suspected Myocardial Infarction Study, g. Lancet Digit Health 6, e729-e738 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39214763
Circulating miRNAs modulating systemic low-grade inflammation and affecting neurodegeneration. Van der Auwera, S., Ameling, S., Wittfeld, K., Bulow, R., Nauck, M., Volzke, H., Volker, U. & Grabe, H. J. Prog Neuropsychopharmacol Biol Psychiatry 135, 111130 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39209100
Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants. Young, W. J., van der Most, P. J., Bartz, T. M., Bos, M. M., Biino, G., Duong, T., Foco, L., Lominchar, J. T., Muller-Nurasyid, M., Nardone, G. G., Pecori, A., Ramirez, J., Repetto, L., Schramm, K., Shen, X., van Duijvenboden, S., van Heemst, D., Weiss, S., Yao, J., Benjamins, J. W., Alonso, A., Spedicati, B., Biggs, M. L., Brody, J. A., Dorr, M., Fuchsberger, C., Gogele, M., Guo, X., Ikram, M. A., Jukema, J. W., Kaab, S., Kanters, J. K., Lifelines Cohort, S., Lin, H. J., Linneberg, A., Nauck, M., Nolte, I. M., Pianigiani, G., Santin, A., Soliman, E. Z., Tesolin, P., Vaccargiu, S., Waldenberger, M., van der Harst, P., Verweij, N., Arking, D. E., Concas, M. P., De Grandi, A., Girotto, G., Grarup, N., Kavousi, M., Mook-Kanamori, D. O., Navarro, P., Orini, M., Padmanabhan, S., Pattaro, C., Peters, A., Pirastu, M., Pramstaller, P. P., Heckbert, S. R., Sinner, M., Snieder, H., Volker, U., Wilson, J. F., Gauderman, W. J., Lambiase, P. D., Sotoodehnia, N., Tinker, A., Warren, H. R., Noordam, R. & Munroe, P. B. J Am Heart Assoc 13, e034760 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39206732
Juli
Paper of the Month
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis
DZHK-Autor:innen: Florian Gaertner, Anne Dueck, Kami Pekayvaz, Christian Schulz, Konstantin Stark, Tobias Petzold, Stefan Engelhardt, Matthias Heinig, Steffen Massberg. Nature.
Atrial fibrillation burden: a new outcome predictor and therapeutic target. Becher, N., Metzner, A., Toennis, T., Kirchhof, P. & Schnabel, R. B. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38953776
Neuroimmune crosstalk : How mental stress fuels vascular inflammation. Meyer-Lindemann, U. & Sager, H. B. Herz (2024). https://www.ncbi.nlm.nih.gov/pubmed/38954012
Estimated Annual Healthcare Costs After Acute Pulmonary Embolism: Results From a Prospective Multicentre Cohort Study. Mohr, K., Mildenberger, P., Neusius, T., Christodoulou, K. C., Farmakis, I. T., Kaier, K., Barco, S., Klok, F. A., Hobohm, L., Keller, K., Becker, D., Abele, C., Bruch, L., Ewert, R., Schmidtmann, I., Wild, P. S., Rosenkranz, S., Konstantinides, S. V., Binder, H. & Valerio, L. Eur Heart J Qual Care Clin Outcomes (2024). https://www.ncbi.nlm.nih.gov/pubmed/38950900
Sex hormone-binding globulin may explain sex differences for glucose homeostasis and incidence of type 2 diabetes: the KORA study. Raeisi-Dehkordi, H., Amiri, M., Rathmann, W., Zeller, T., Adamski, J., Bano, A., van der Schouw, Y. T., Thorand, B., Muka, T. & Nano, J. Eur J Epidemiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38954350
Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Trastulla, L., Dolgalev, G., Moser, S., Jimenez-Barron, L. T., Andlauer, T. F. M., von Scheidt, M., Schizophrenia Working Group of the Psychiatric Genomics, C., Budde, M., Heilbronner, U., Papiol, S., Teumer, A., Homuth, G., Volzke, H., Dorr, M., Falkai, P., Schulze, T. G., Gagneur, J., Iorio, F., Muller-Myhsok, B., Schunkert, H. & Ziller, M. J. Nat Commun 15, 5534 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38951512
App-Based Addiction Prevention at German Vocational Schools: Implementation and Reach for a Cluster-Randomized Controlled Trial. Guertler, D., Blasing, D., Moehring, A., Meyer, C., Brandt, D., Schmidt, H., Rehbein, F., Neumann, M., Dreissigacker, A., Bischof, A., Bischof, G., Surig, S., Hohls, L., Hagspiel, M., Wurm, S., Haug, S. & Rumpf, H. J. Prev Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/38958917
Incidence and Outcomes of Emergency Intraprocedural Surgical Conversion During Transcatheter Aortic Valve Implantation: A Multicentric Analysis. Marin-Cuartas, M., de Waha, S., de la Cuesta, M., Deo, S. V., Kaminski, A., Fach, A., Meyer, A. L., Popov, A. F., Hagl, C., Joskowiak, D., Kuhn, E. W., Ius, F., Leuschner, F., Awad, G., Thiele, H., Abdalla, A., Garbade, J., Ender, J., Wehrmann, K., Eghbalzadeh, K., Vitanova, K., Conradi, L., Diab, M., Franz, M., Geyer, M., Meineri, M., Misfeld, M., Abdel-Wahab, M., Bhadra, O. D., Osteresch, R., Sandoval Boburg, R., Lange, R., Leontyev, S., Saha, S., Desch, S., Lehmann, S., Noack, T., Doenst, T., Borger, M. A. & Kiefer, P. J Am Heart Assoc 13, e033964 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38958140
Pulmonary vein reconnection and repeat ablation characteristics following cryoballoon-compared to radiofrequency-based pulmonary vein isolation. Obergassel, J., Nies, M., Taraba, S., Rottner, L., Lemoine, M. D., My, I., Moser, F., Riess, J. L., Schenker, N., Dinshaw, L., Schleberger, R., Reissmann, B., Meyer, C., Willems, S., Rillig, A., Kirchhof, P. & Metzner, A. J Cardiovasc Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38956821
The effect of high-dose selenium on mortality and postoperative organ dysfunction in post-cardiotomy cardiogenic shock patients supported with mechanical circulatory support - A post-hoc analysis of the SUSTAIN CSX trial. Ott, S., Dresen, E., Lee, Z. Y., Muller-Wirtz, L. M., Procopiuc, L., Ekrami, E., Pitts, L., Hellner, N., Catena, D., Duerr, G. D., Wittmann, M., Waeschle, R. M., Elke, G., O'Brien, B., Heyland, D. K. & Stoppe, C. J Crit Care 83, 154853 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38955117
Evaluation of frailty in geriatric patients undergoing cardiac rehabilitation after cardiac procedure: results of a prospective, cross-sectional study. Steinmetz, C., Krause, L., Sulejmanovic, S., Kaumkotter, S., Hartog, J., Scheenstra, B., Stefan, F., Mengden, T., Grefe, C., Knoglinger, E., Reiss, N., Bjarnason-Wehrens, B., Schmidt, T., Sadlonova, M., von Arnim, C. A. F. & Heinemann, S. BMC Sports Sci Med Rehabil 16, 146 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38956610
Impact of Lipoprotein(a) Level on Low-Density Lipoprotein Cholesterol- or Apolipoprotein B-Related Risk of Coronary Heart Disease. Arnold, N., Blaum, C., Gossling, A., Brunner, F. J., Bay, B., Zeller, T., Ferrario, M. M., Brambilla, P., Cesana, G., Leoni, V., Palmieri, L., Donfrancesco, C., Ojeda, F., Linneberg, A., Soderberg, S., Iacoviello, L., Gianfagna, F., Costanzo, S., Sans, S., Veronesi, G., Thorand, B., Peters, A., Tunstall-Pedoe, H., Kee, F., Salomaa, V., Schnabel, R. B., Kuulasmaa, K., Blankenberg, S., Waldeyer, C., Koenig, W. & BiomarCa, R. E. I. J Am Coll Cardiol 84, 165-177 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38960510
[Oral anticoagulation with Edoxaban for stroke prevention in patients with atrial fibrillation: Analysis of 1-year follow-up data of routine clinical practice in Germany, Austria and Switzerland (DACH) from the ETNA-AF registry]. Dinshaw, L., Steffel, J., Gotte, A., Weiss, T. W., Waltenberger, J. & Kirchhof, P. Dtsch Med Wochenschr 149, e58-e66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38959945
Imaging of Existing and Newly Translated Proteins Elucidates Mechanisms of Sarcomere Turnover. Douvdevany, G., Erlich, I., Haimovich-Caspi, L., Mashiah, T., Prondzynski, M., Pricolo, M. R., Alegre-Cebollada, J., Linke, W. A., Carrier, L. & Kehat, I. Circ Res135, 474-487 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38962864
Impact of sex on clinical outcome in early Multiple Sclerosis. Gottwald, N. S., Asseyer, S., Chien, C., Brasanac, J., Nauman, A. T., Rust, R., Schmitz-Hubsch, T., Strobl, J. B., Ruprecht, K., Paul, F., Regitz-Zagrosek, V., Gold, S. M. & Sperber, P. S. Mult Scler Relat Disord 88, 105749 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38959589
Sex-dependent differences in macaque brain mitochondria. Guerrero, I., Yoval-Sanchez, B., Konrad, C., Manfredi, G., Wittig, I. & Galkin, A. Biochim Biophys Acta Bioenerg 1865, 149494 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38960079
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE(-/-) mice. Bruckner, A., Brandtner, A., Rieck, S., Matthey, M., Geisen, C., Fels, B., Stei, M., Kusche-Vihrog, K., Fleischmann, B. K. & Wenzel, D. Angiogenesis (2024). https://www.ncbi.nlm.nih.gov/pubmed/38965173
Gut dysbiosis contributes to TMAO accumulation in CKD. Holle, J., McParland, V., Anandakumar, H., Gerritzmann, F., Behrens, F., Schumacher, F., Thumfart, J., Eckardt, K. U., Kleuser, B., Bartolomaeus, H. & Wilck, N. Nephrol Dial Transplant (2024). https://www.ncbi.nlm.nih.gov/pubmed/38964836
Is an accurate self-perceived health risk beneficial for patients to minimize prehospital delay time at onset of a ST-segment elevated myocardial infarction (STEMI)? Ladwig, K. H., Olliges, E., Albarqouni, L., Hoschar, S., Ma, W. & Fang, X. Herz 49, 270-276 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38965126
Infective endocarditis and spondylodiscitis-impact of sequence of surgical therapy on survival and recurrence rate. Weber, C., Misfeld, M., Diab, M., Saha, S., Elderia, A., Marin-Cuartas, M., Luehr, M., Yagdiran, A., Eysel, P., Jung, N., Hagl, C., Doenst, T., Borger, M. A., Kernich, N. & Wahlers, T. Eur J Cardiothorac Surg 66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38964339
Atavism as a cause of dilative cardiomyopathy. Fastenrath, F., Tavakoli, A., Duerschmied, D., Haghi, D., Ayx, I. & Papavassiliu, T. Hellenic J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38969174
Editorial to: Extensive ablation for persistent atrial fibrillation patients with mitral regurgitation: Insights from the EARNEST-PVI prospective randomized trial. Heeger, C. H. & Alagjozovski, H. Int J Cardiol 412, 132299 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38968973
Advances in nucleic acid-targeted therapies for cardiovascular disease prevention. Makhmudova, U., Steinhagen-Thiessen, E., Volpe, M. & Landmesser, U. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38970537
The impact of onset-to-cut time in surgery for stable acute type a aortic dissection-a single-center retrospective cohort study. Pitts, L., Kofler, M., Montagner, M., Heck, R., Dominik Kurz, S., Claudiu Paun, A., Falk, V. & Kempfert, J. Interdiscip Cardiovasc Thorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38970376
Effects of baroreflex activation therapy on cardiac function and morphology. Schafer, A. C., Wallbach, M., Schroer, C., Lehnig, L. Y., Luders, S., Hasenfuss, G., Wachter, R. & Koziolek, M. J. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38970313
Reduced dynamic changes in pulmonary artery compliance during isometric handgrip exercise in patients with heart failure. Hashemi, D., Hou, X., Doeblin, P., Weiss, J., Beyer, R., Neye, M., Erley, J., Bucius, P., Tanacli, R., Kuehne, T., Kelm, M., Blum, M., Edelmann, F., Kuebler, W. M., Dungen, H. D., Schuster, A., Stoiber, L. & Kelle, S. Sci Rep 14, 15594 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38971904
A multicenter study of asymmetric and symmetric dimethylarginine as predictors of mortality risk in hospitalized COVID-19 patients. Hannemann, J., Zink, A., Mileva, Y., Balfanz, P., Dahl, E., Volland, S., Illig, T., Schwedhelm, E., Kurth, F., Stege, A., Aepfelbacher, M., Hoffmann, A. & Boger, R. Sci Rep 14, 15739 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38977837
Right ventricular strain to systolic pulmonary artery pressure ratio in response to treatment of pulmonary arterial hypertension. Pott, J., Csengeri, D., Ostermann, J., Klose, H., Sinning, C. & Harbaum, L. ERJ Open Res 10 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38978554
Quantitative flow ratio or angiography for the assessment of non-culprit lesions in acute coronary syndromes, a randomized trial. Ullrich-Daub, H., Olschewski, M., Schnorbus, B., Belhady, A., Kohler, T., Vosseler, M., Munzel, T. & Gori, T. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38980329
Associations between adrenal gland volume and adipose tissue compartments - a whole body MRI study. Askani, E., Rospleszcz, S., Lorbeer, R., Wintergerst, C., Muller-Peltzer, K., Kiefer, L. S., Kellner, E., Reisert, M., Rathmann, W., Peters, A., Schlett, C. L., Bamberg, F. & Storz, C. Nutr Metab (Lond) 21, 45 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38982517
The oral microbiome is associated with HPA axis response to a psychosocial stressor. Charalambous, E. G., Meriaux, S. B., Guebels, P., Muller, C. P., Leenen, F. A. D., Elwenspoek, M. M. C., Thiele, I., Hertel, J. & Turner, J. D. Sci Rep 14, 15841 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38982178
Predictors of ventricular tachyarrhythmia in patients with a wearable cardioverter defibrillator: an international multicenter registry. Kreimer, F., Koepsel, K., Gotzmann, M., Kovacs, B., Dreher, T. C., Blockhaus, C., Klein, N., Kuntz, T., Shin, D. I., Lapp, H., Rosenkaimer, S., Abumayyaleh, M., Hamdani, N., Saguner, A. M., Erath, J. W., Duru, F., Beiert, T., Schiedat, F., Weth, C., Custodis, F., Akin, I., Mugge, A., Aweimer, A. & El-Battrawy, I. J Interv Card Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38985244
Nexilin in cardiomyopathy: unveiling its diverse roles with special focus on endocardial fibroelastosis. Rahimzadeh, M., Tennstedt, S. & Aherrahrou, Z. Heart Fail Rev (2024). https://www.ncbi.nlm.nih.gov/pubmed/38985384
Clinical impact of novel CMR technology on patients with congenital heart disease. A scientific statement of the Association for European Pediatric and Congenital Cardiology (AEPC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC. Voges, I., Raimondi, F., McMahon, C. J., Ait-Ali, L., Babu-Narayan, S. V., Botnar, R. M., Burkhardt, B., Gabbert, D. D., Grosse-Wortmann, L., Hasan, H., Hansmann, G., Helbing, W. A., Krupickova, S., Latus, H., Martini, N., Martins, D., Muthurangu, V., Ojala, T., van Ooij, P., Pushparajah, K., Rodriguez-Palomares, J., Sarikouch, S., Grotenhuis, H. B. & Greil, F. G. Eur Heart J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38985851
Serum Concentrations of Matrix Metalloproteinase-1 and Procollagen Type I Carboxy Terminal Propeptide Discriminate Infarct-Like Myocarditis and Non-ST-Segment-Elevation Myocardial Infarction. Bacmeister, L., Cavus, E., Bohnen, S., Tahir, E., Wolf, H., Buellesbach, A., Heidenreich, A., Haacke, V. K., Weber, S., Hilgendorf, I., Zeller, T., Ojeda, F., Radunski, U. K., Lund, G. K., Adam, G., Blankenberg, S., Westermann, D., Muellerleile, K. & Lindner, D. J Am Heart Assoc 13, e034194 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38989835
Biostatistical Aspects of Whole Genome Sequencing Studies: Preprocessing and Quality Control. Betschart, R. O., Riccio, C., Aguilera-Garcia, D., Blankenberg, S., Guo, L., Moch, H., Seidl, D., Solleder, H., Thalen, F., Thiery, A., Twerenbold, R., Zeller, T., Zoche, M. & Ziegler, A. Biom J 66, e202300278 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38988195
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis. Gaertner, F., Ishikawa-Ankerhold, H., Stutte, S., Fu, W., Weitz, J., Dueck, A., Nelakuditi, B., Fumagalli, V., van den Heuvel, D., Belz, L., Sobirova, G., Zhang, Z., Titova, A., Navarro, A. M., Pekayvaz, K., Lorenz, M., von Baumgarten, L., Kranich, J., Straub, T., Popper, B., Zheden, V., Kaufmann, W. A., Guo, C., Piontek, G., von Stillfried, S., Boor, P., Colonna, M., Clauss, S., Schulz, C., Brocker, T., Walzog, B., Scheiermann, C., Aird, W. C., Nerlov, C., Stark, K., Petzold, T., Engelhardt, S., Sixt, M., Hauschild, R., Rudelius, M., Oostendorp, R. A. J., Iannacone, M., Heinig, M. & Massberg, S. Nature 631, 645-653 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38987596
Incidence and impact of venous thromboembolism in hospitalized patients with acute pancreatitis. Keller, K., Sivanathan, V., Farmakis, I. T., Schmitt, V. H., Espinola-Klein, C., Schmidt, F. P., Munzel, T., Konstantinides, S. & Hobohm, L. Dig Liver Dis (2024). https://www.ncbi.nlm.nih.gov/pubmed/38987040
Impact of Intraprocedural Mitral Regurgitation and Gradient Following Transcatheter Edge-to-Edge Repair for Primary Mitral Regurgitation. Ludwig, S., Koell, B., Weimann, J., Donal, E., Patel, D., Stolz, L., Tanaka, T., Scotti, A., Trenkwalder, T., Rudolph, F., Samim, D., von Stein, P., Giannini, C., Dreyfus, J., Paradis, J. M., Adamo, M., Karam, N., Bohbot, Y., Bernard, A., Melica, B., Quagliana, A., Lavie Badie, Y., Kessler, M., Chehab, O., Redwood, S., Lubos, E., Sondergaard, L., Metra, M., Primerano, C., Iliadis, C., Praz, F., Gercek, M., Xhepa, E., Nickenig, G., Latib, A., Schofer, N., Makkar, R., Granada, J. F., Modine, T., Hausleiter, J., Kalbacher, D., Coisne, A. & Investigators, P.-M. JACC Cardiovasc Interv 17, 1559-1573 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38986655
The reactive pyruvate metabolite dimethylglyoxal mediates neurological consequences of diabetes. Rhein, S., Costalunga, R., Inderhees, J., Gurtzgen, T., Faupel, T. C., Shaheryar, Z., Arrulo Pereira, A., Othman, A., Begemann, K., Binder, S., Stolting, I., Dorta, V., Nawroth, P. P., Fleming, T., Oexle, K., Prevot, V., Nogueiras, R., Meyhofer, S., Meyhofer, S. M. & Schwaninger, M. Nat Commun 15, 5745 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38987239
Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C collaborative meta-analysis of randomised controlled trials. Apperloo, E. M., Neuen, B. L., Fletcher, R. A., Jongs, N., Anker, S. D., Bhatt, D. L., Butler, J., Cherney, D. Z. I., Herrington, W. G., Inzucchi, S. E., Jardine, M. J., Liu, C. C., Mahaffey, K. W., McGuire, D. K., McMurray, J. J. V., Neal, B., Packer, M., Perkovic, V., Sabatine, M. S., Solomon, S. D., Staplin, N., Szarek, M., Vaduganathan, M., Wanner, C., Wheeler, D. C., Wiviott, S. D., Zannad, F. & Heerspink, H. J. L. Lancet Diabetes Endocrinol 12, 545-557 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38991584
Treatment of sleep apnoea early after myocardial infarction with adaptive servo-ventilation - a proof-of-concept randomised controlled trial. Arzt, M., Fox, H., Stadler, S., Hetzenecker, A., Oldenburg, O., Hamer, O. W., Poschenrieder, F., Wiest, C., Tanacli, R., Kelle, S., Bruch, L., Seidel, M., Koller, M., Zeman, F., Buchner, S. & Investigators, T.-A. I. Eur Respir J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38991707
Effect of empagliflozin on total myocardial infarction events by type and additional coronary outcomes: insights from the randomized EMPA-REG OUTCOME trial. Fitchett, D., Zinman, B., Inzucchi, S. E., Wanner, C., Anker, S. D., Pocock, S., Mattheus, M., Vedin, O. & Lund, S. S. Cardiovasc Diabetol 23, 248 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38992713
Interpretation of elevated baseline concentrations and serial changes of high-sensitivity cardiac troponin T in confirmed muscular dystrophies. Yildirim, M., Reich, C., Salbach, C., Pribe-Wolferts, R., Milles, B. R., Tager, T., Mueller-Hennessen, M., Weiler, M., Meder, B., Frey, N. & Giannitsis, E. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38992971
CD74 is a functional MIF receptor on activated CD4(+) T cells. Zhang, L., Woltering, I., Holzner, M., Brandhofer, M., Schaefer, C. C., Bushati, G., Ebert, S., Yang, B., Muenchhoff, M., Hellmuth, J. C., Scherer, C., Wichmann, C., Effinger, D., Hubner, M., El Bounkari, O., Scheiermann, P., Bernhagen, J. & Hoffmann, A. Cell Mol Life Sci 81, 296 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38992165
A Novel C3/C4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction. Potlitz, F., Palm, G. J., Bodtke, A., Lammers, M., Schade, D. & Link, A. Molecules 29 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38999014
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome. Busley, A. V., Gutierrez-Gutierrez, O., Hammer, E., Koitka, F., Mirzaiebadizi, A., Steinegger, M., Pape, C., Bohmer, L., Schroeder, H., Kleinsorge, M., Engler, M., Cirstea, I. C., Gremer, L., Willbold, D., Altmuller, J., Marbach, F., Hasenfuss, G., Zimmermann, W. H., Ahmadian, M. R., Wollnik, B. & Cyganek, L. Cell Rep43, 114448 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39003740
Clinical outcomes and predictors of transapical transcatheter mitral valve replacement: the Tendyne Expanded Clinical Study. Conradi, L., Ludwig, S., Sorajja, P., Duncan, A., Bethea, B., Dahle, G., Babaliaros, V., Guerrero, M., Thourani, V., Dumonteil, N., Modine, T., Garatti, A., Denti, P., Leipsic, J., Chuang, M. L., Blanke, P., Muller, D. W. & Badhwar, V. EuroIntervention 20, e887-e897 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39007829
Novel Long Noncoding RNA HEAT4 Affects Monocyte Subtypes, Reducing Inflammation and Promoting Vascular Healing. Kneuer, J. M., Grajek, I. A., Winkler, M., Erbe, S., Meinecke, T., Weiss, R., Garfias-Veitl, T., Sheikh, B. N., Konig, A. C., Mobius-Winkler, M. N., Kogel, A., Kresoja, K. P., Rosch, S., Kokot, K. E., Filipova, V., Gaul, S., Thiele, H., Lurz, P., von Haehling, S., Speer, T., Laufs, U. & Boeckel, J. N. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39005211
Renal protection after hemorrhagic shock in rats: Possible involvement of SUMOylation. Oliveira, F., Sousa Soares, E., Pillmann Ramos, H., Lattig-Tunnemann, G., Harms, C., Cimarosti, H. & Sordi, R. Biochem Pharmacol 227, 116425 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39004233
Learning carotid vessel wall segmentation in black-blood MRI using sparsely sampled cross-sections from 3D data. Rahlfs, H., Hullebrand, M., Schmitter, S., Strecker, C., Harloff, A. & Hennemuth, A. J Med Imaging (Bellingham) 11, 044503 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39006308
Simple but useful: DI in the assessment of patients with aortic stenosis. Schneider-Reigbert, M. & Dreger, H. Echocardiography 41, e15889 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39008001
TAVI in moderate aortic stenosis: the earlier the better? Schofer, N. & Ludwig, S. EuroIntervention20, e840-e842 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39007827
Loss of Y Chromosome and Cardiovascular Events in Chronic Kidney Disease. Weyrich, M., Cremer, S., Gerster, M., Sarakpi, T., Rasper, T., Zewinger, S., Patyna, S. R., Leistner, D. M., Heine, G. H., Wanner, C., Marz, W., Fliser, D., Dimmeler, S., Zeiher, A. M. & Speer, T. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/39005209
Cardiac wasting and cancer. Anker, M. S., Rassaf, T., Zamorano, J. L., Khan, M. S. & Landmesser, U. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39011778
Left Atrial Roof Enlargement Is a Distinct Feature of Heart Failure With Preserved Ejection Fraction. Backhaus, S. J., Nasopoulou, A., Lange, T., Schulz, A., Evertz, R., Kowallick, J. T., Hasenfuss, G., Lamata, P. & Schuster, A. Circ Cardiovasc Imaging17, e016424 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39012942
Quantitative assessment of cardiac (123)iodo-metaiodobenzylguanidine SPECT/CT in patients with arrhythmogenic right ventricular cardiomyopathy: novel insight in disease monitoring. Hagen, J. M., Zacherl, M. J., Brendel, M., Clauss, S., Kaab, S., Bartenstein, P., Todica, A., Boening, G. & Fischer, M. J Nucl Cardiol, 101911 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009215
Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy. Paulke, N. J., Fleischhacker, C., Wegener, J. B., Riedemann, G. C., Cretu, C., Mushtaq, M., Zaremba, N., Mobius, W., Zuhlke, Y., Wedemeyer, J., Liebmann, L., Gorshkova, A. A., Kownatzki-Danger, D., Wagner, E., Kohl, T., Wichmann, C., Jahn, O., Urlaub, H., Toischer, K., Hasenfuss, G., Moser, T., Preobraschenski, J., Lenz, C., Rog-Zielinska, E. A., Lehnart, S. E. & Brandenburg, S. Circ Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39011635
RhoA-mediated G(12)-G(13) signaling maintains muscle stem cell quiescence and prevents stem cell loss. Peng, Y., Du, J., Li, R., Gunther, S., Wettschureck, N., Offermanns, S., Wang, Y., Schneider, A. & Braun, T. Cell Discov 10, 76 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009565
LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome. Pozojevic, J., Sivaprasad, R., Lass, J., Haarich, F., Trinh, J., Kakar, N., Schulz, K., Handler, K., Verrijn Stuart, A. A., Giltay, J. C., van Gassen, K. L., Caliebe, A., Holterhus, P. M., Spielmann, M. & Hornig, N. C. Sci Rep 14, 16302 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009627
Personalized care in dilated cardiomyopathy: Rationale and study design of the activeDCM trial. Sedaghat-Hamedani, F., Amr, A., Betz, T., Kayvanpour, E., Reich, C., Wettstein, R., Heinze, O., Mohr, I., Krisam, R., Sander, A., Klose, C., Friedmann-Bette, B., Frey, N. & Meder, B. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39010317
Influence of AAV vector tropism on long-term expression and Fc-gamma receptor binding of an antibody targeting SARS-CoV-2. Wagner, J. T., Muller-Schmucker, S. M., Wang, W., Arnold, P., Uhlig, N., Issmail, L., Eberlein, V., Damm, D., Roshanbinfar, K., Ensser, A., Oltmanns, F., Peter, A. S., Temchura, V., Schrodel, S., Engel, F. B., Thirion, C., Grunwald, T., Wuhrer, M., Grimm, D. & Uberla, K. Commun Biol 7, 865 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39009807
When size matters: A novel compact Cas12a variant for in vivo genome editing. Bubeck, F. & Grimm, D. PLoS Biol 22, e3002637 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39018342
Prediction of Left Ventricle Pressure Indices Via a Machine Learning Approach Combining ECG, Pulse Oximetry, and Cardiac Sounds: a Preclinical Feasibility Study. Fassina, L., Muzio, F. P. L., Berboth, L., Otvos, J., Faragli, A. & Alogna, A. J Cardiovasc Transl Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39017912
Myeloid cell-derived interleukin-6 induces vascular dysfunction and vascular and systemic inflammation. Knopp, T., Jung, R., Wild, J., Bochenek, M. L., Efentakis, P., Lehmann, A., Bieler, T., Garlapati, V., Richter, C., Molitor, M., Perius, K., Finger, S., Lagrange, J., Ghasemi, I., Zifkos, K., Kommoss, K. S., Masri, J., Reissig, S., Randriamboavonjy, V., Wunderlich, T., Hovelmeyer, N., Weber, A. N. R., Mufazalov, I. A., Bosmann, M., Bechmann, I., Fleming, I., Oelze, M., Daiber, A., Munzel, T., Schafer, K., Wenzel, P., Waisman, A. & Karbach, S. Eur Heart J Open 4, oeae046 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39015379
[Cardiac irradiation for improvement of left ventricular function]. Mehrhof, F., Hohendanner, F., Blanck, O., Hindricks, G., Zips, D. & Hausmann, F. Strahlenther Onkol 200, 847-849 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39017687
TAVR-in-TAVR in a Patient With a 12-Year-Old Chimney Stent: The Inverted Culotte Double Chimney Technique. Dreger, H., Al Harbi, A. S., Geyer, T., Dushe, S., Sundermann, S. H., Unbehaun, A. & Spethmann, S. JACC Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39023449
Improved Detection of Small and Low-Density Plaques in Virtual Noncontrast Imaging-based Calcium Scoring at Photon-Counting Detector CT. Fink, N., Emrich, T., Schoepf, U. J., Zsarnoczay, E., O'Doherty, J., Halfmann, M. C., Griffith, J. P., 3rd, Pinos, D., Suranyi, P., Baruah, D., Kabakus, I. M., Ricke, J. & Varga-Szemes, A. Radiol Cardiothorac Imaging 6, e230328 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39023373
Transportation Model for Acute Aortic Dissection: Implications for Reduced Treatment Centers. Goehlich, A., Prasse, P., Zaschke, L., Habazettl, H., Falk, V. & Kurz, S. D. Eur J Cardiothorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39024021
A case report of a malignant melanoma in the cardiologic diagnostic workup. Jahnke, C., Gramlich, R., Sander, C., Willems, S. & Chung, D. U. Eur Heart J Case Rep 8, ytae312 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39021359
Catheter-based ablation to improve outcomes in patients with atrial fibrillation and heart failure with preserved ejection fraction: Rationale and design of the CABA-HFPEF-DZHK27 trial. Parwani, A. S., Kaab, S., Friede, T., Tilz, R. R., Bauersachs, J., Frey, N., Hindricks, G., Lewalter, T., Rienstra, M., Rillig, A., Scherr, D., Steven, D., Kirchhof, P. & Pieske, B. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/39023141
Endothelin-1 influences mechanical properties and contractility of hiPSC derived cardiomyocytes resulting in diastolic dysfunction. Redwanz, C., Pires, R. H., Biedenweg, D., Gross, S., Otto, O. & Konemann, S. J Mol Cell Cardiol 194, 105-117 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39019395
Ventricular unloading causes prolongation of the QT interval and induces ventricular arrhythmias in rat hearts. Schwoerer, A. P., Biermann, D. & Ehmke, H. Front Physiol 15, 1346093 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39022307
Chaos control in cardiac dynamics: terminating chaotic states with local minima pacing. Suth, D., Luther, S. & Lilienkamp, T. Front Netw Physiol 4, 1401661 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39022296
Split intein-mediated protein trans-splicing to express large dystrophins. Tasfaout, H., Halbert, C. L., McMillen, T. S., Allen, J. M., Reyes, T. R., Flint, G. V., Grimm, D., Hauschka, S. D., Regnier, M. & Chamberlain, J. S. Nature (2024). https://www.ncbi.nlm.nih.gov/pubmed/39020181
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Widjaja, A. A., Lim, W. W., Viswanathan, S., Chothani, S., Corden, B., Dasan, C. M., Goh, J. W. T., Lim, R., Singh, B. K., Tan, J., Pua, C. J., Lim, S. Y., Adami, E., Schafer, S., George, B. L., Sweeney, M., Xie, C., Tripathi, M., Sims, N. A., Hubner, N., Petretto, E., Withers, D. J., Ho, L., Gil, J., Carling, D. & Cook, S. A. Nature (2024). https://www.ncbi.nlm.nih.gov/pubmed/39020175
Cost-effectiveness of applying high-sensitivity troponin I to a score for cardiovascular risk prediction in asymptomatic population. Julicher, P., Makarova, N., Ojeda, F., Giusepi, I., Peters, A., Thorand, B., Cesana, G., Jorgensen, T., Linneberg, A., Salomaa, V., Iacoviello, L., Costanzo, S., Soderberg, S., Kee, F., Giampaoli, S., Palmieri, L., Donfrancesco, C., Zeller, T., Kuulasmaa, K., Tuovinen, T., Lamrock, F., Conrads-Frank, A., Brambilla, P., Blankenberg, S. & Siebert, U. PLoS One 19, e0307468 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028718
Genetic testing in early-onset atrial fibrillation. Kany, S., Jurgens, S. J., Ramo, J. T., Christophersen, I. E., Rienstra, M., Chung, M. K., Olesen, M. S., Ackerman, M. J., McNally, E. M., Semsarian, C., Schnabel, R. B., Wilde, A. A. M., Benjamin, E. J., Rehm, H. L., Kirchhof, P., Bezzina, C. R., Roden, D. M., Shoemaker, M. B. & Ellinor, P. T. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028637
Left atrial appendage closure for stroke prevention in atrial fibrillation: current status and perspectives. Landmesser, U., Skurk, C., Tzikas, A., Falk, V., Reddy, V. Y. & Windecker, S. Eur Heart J 45, 2914-2932 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39027946
Effect of inferior caval valve implantation on circulating immune cells and inflammatory mediators in severe tricuspid regurgitation. Mattig, I., Hewing, B., Knebel, F., Meisel, C., Ludwig, A., Konietschke, F., Stangl, V., Stangl, K., Laule, M. & Dreger, H. BMC Cardiovasc Disord 24, 373 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39026154
Association of aortic diameters and mortality in the general population-an MRI-based study. Mensel, B., Mahnken, A. H., Kaiser, E., Volzke, H., Dorr, M., Felix, S. B., Ittermann, T., Lieb, W. & Lorbeer, R. Eur Radiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39026062
Gene expression networks in endothelial cells from failing human hearts. Wirth, L., Erny, E., Krane, M., Lahm, H., Hein, L., Gilsbach, R. & Lother, A. Am J Physiol Heart Circ Physiol 327, H573-H581 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028282
Trophoblast Side-Population Markers are Dysregulated in Preeclampsia and Fetal Growth Restriction. Wong, G. P., Hartmann, S., Simmons, D. G., Ellis, S., Nonn, O., Cannon, P., Nguyen, T. V., Nguyen, A., Bartho, L. A., Tong, S., Hannan, N. J. & Kaitu'u-Lino, T. J. Stem Cell Rev Rep (2024). https://www.ncbi.nlm.nih.gov/pubmed/39028417
Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A ten-year retrospective study in a German tertiary care hospital. Yu, Y., Lettow, I., Roedl, K., Jarczak, D., Pinnschmidt, H., Reichenspurner, H., Bernhardt, A. M., Soffker, G., Schrage, B., Haar, M., Weber, T., Frings, D., Kluge, S. & Fischer, M. J Crit Care84, 154880 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39024824
Machine learning for catalysing the integration of noncoding RNA in research and clinical practice. de Gonzalo-Calvo, D., Karaduzovic-Hadziabdic, K., Dalgaard, L. T., Dieterich, C., Perez-Pons, M., Hatzigeorgiou, A., Devaux, Y. & Kararigas, G. EBioMedicine 106, 105247 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39029428
Increased expression of human endogenous retrovirus K in endomyocardial biopsies from patients with cardiomyopathy - a transcriptomics meta-analysis. Heckmann, M. B., Finke, D., Sauerbrey, L., Frey, N. & Lehmann, L. H. BMC Genomics 25, 707 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39033293
Prognostic impact of quantitative flow ratio (QFR)-consistent complete revascularization in patients with myocardial infarction and multivessel coronary artery disease. Erbay, A., Penzel, L., Abdelwahed, Y. S., Heuberger, A., Schatz, A. S., Seppelt, C., Schlender, L. S., Steiner, J., Haghikia, A., Steven, S., Landmesser, U., Stahli, B. E. & Leistner, D. M. Am Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/39033995
Effects of Oral Butyrate on Blood Pressure in Patients With Hypertension: A Randomized, Placebo-Controlled Trial. Verhaar, B. J. H., Wijdeveld, M., Wortelboer, K., Rampanelli, E., Levels, J. H. M., Collard, D., Cammenga, M., Nageswaran, V., Haghikia, A., Landmesser, U., Li, X. S., DiDonato, J. A., Hazen, S. L., Garrelds, I. M., Danser, A. H. J., van den Born, B. H., Nieuwdorp, M. & Muller, M. Hypertension (2024). https://www.ncbi.nlm.nih.gov/pubmed/39034917
Cross-species single-cell RNA sequencing reveals divergent phenotypes and activation states of adaptive immunity in human carotid and experimental murine atherosclerosis. Horstmann, H., Michel, N. A., Sheng, X., Hansen, S., Lindau, A., Pfeil, K., Fernandez, M. C., Marchini, T., Winkels, H., Mitre, L. S., Abogunloko, T., Li, X., Mwinyella, T. B., Gissler, M. C., Bugger, H., Heidt, T., Buscher, K., Hilgendorf, I., Stachon, P., Piepenburg, S., Verheyen, N., Rathner, T., Gerhardt, T., Siegel, P. M., Oswald, W. K., Cohnert, T., Zernecke, A., Madl, J., Kohl, P., Foks, A. C., von Zur Muehlen, C., Westermann, D., Zirlik, A. & Wolf, D. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39041203
Calcium-activated potassium channels as amplifiers of TRPV4-mediated pulmonary edema formation in male mice. Li, M., Roeder, J., Blazquez-Prieto, J., Schulz, S., Naujox, J., Falivene, J., Erfinanda, L., Liedtke, W., Albaiceta, G. M., Kuebler, W. M. & Michalick, L. Anesthesiology (2024). https://www.ncbi.nlm.nih.gov/pubmed/39042042
Evaluation of cell survival in different 3D-printed geometric shapes of human iPSC-derived engineered heart tissue. Yildirim, Y., Degener, L., Reuter, L., Petersen, J., Gabel, L., Sommer, A., Pahrmann, C., Reichenspurner, H. & Pecha, S. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/39041632
Introducing Attribute Association Graphs to Facilitate Medical Data Exploration: Development and Evaluation Using Epidemiological Study Data. Bellmann, L., Wiederhold, A. J., Trube, L., Twerenbold, R., Uckert, F. & Gottfried, K. JMIR Med Inform12, e49865 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39046780
Heparin-Induced Thrombocytopenia in Patients Suffering Cardiogenic Shock. Lusebrink, E., Lanz, H., Binzenhofer, L., Hoffmann, S., Hopler, J., Kraft, M., Gade, N., Gmeiner, J., Roden, D., Saleh, I., Hagl, C., Nickenig, G., Massberg, S., Zimmer, S., Jamin, R. N. & Scherer, C. Crit Care Explor 6, e1117 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39045433
A genome-wide association meta-analysis of all-cause and vascular dementia. Mega Vascular Cognitive, I. & Dementia, c. Alzheimers Dement (2024). https://www.ncbi.nlm.nih.gov/pubmed/39046104
CardioTwins: case report of a transcatheter mitral and tricuspid valve implantation in one patient. Schmidt, T., Kuck, K. H., Marquetand, C., Eitel, I. & Frerker, C. Eur Heart J Case Rep 8, ytae336 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39045523
Innate immune memory after brain injury drives inflammatory cardiac dysfunction. Simats, A., Zhang, S., Messerer, D., Chong, F., Beskardes, S., Chivukula, A. S., Cao, J., Besson-Girard, S., Montellano, F. A., Morbach, C., Carofiglio, O., Ricci, A., Roth, S., Llovera, G., Singh, R., Chen, Y., Filser, S., Plesnila, N., Braun, C., Spitzer, H., Gokce, O., Dichgans, M., Heuschmann, P. U., Hatakeyama, K., Beltran, E., Clauss, S., Bonev, B., Schulz, C. & Liesz, A. Cell (2024). https://www.ncbi.nlm.nih.gov/pubmed/39043180
Outcome risk model development for heterogeneity of treatment effect analyses: a comparison of non-parametric machine learning methods and semi-parametric statistical methods. Xu, E., Vanghelof, J., Wang, Y., Patel, A., Furst, J., Raicu, D. S., Neumann, J. T., Wolfe, R., Gao, C. X., McNeil, J. J., Shah, R. C. & Tchoua, R. BMC Med Res Methodol 24, 158 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39044195
Transverse aortic constriction multi-omics analysis uncovers pathophysiological cardiac molecular mechanisms. Gjerga, E., Dewenter, M., Britto-Borges, T., Grosso, J., Stein, F., Eschenbach, J., Rettel, M., Backs, J. & Dieterich, C. Database (Oxford) 2024 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39051433
Iron scavenging and myeloid cell polarization. Ludwig, N., Cucinelli, S., Hametner, S., Muckenthaler, M. U. & Schirmer, L. Trends Immunol 45, 625-638 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39054114
Left ventricular diastolic function assessed by speckle tracking echocardiography in patients with left ventricular aneurysm. Nemchyna, O., Solowjowa, N., Hrytsyna, Y., Dandel, M., Merke, N., Knierim, J., Schoenrath, F., Just, I. A., Hennig, F., Hohendanner, F., Falk, V. & Knosalla, C. Int J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/39052191
Impact of peripheral thyroid hormone balance on liver fat: insights from the NutriAct trial. Sommer-Ballarini, M., Nguyen, T. H., Pletsch-Borba, L., Wernicke, C., Tacke, F., Schwerdtle, T., Pellowski, D., Machann, J., Spranger, J., Wirth, E. K. & Mai, K. Eur J Endocrinol 191, 183-191 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39049801
Combined Organ Transplantation in Patients with Advanced Liver Disease. Zhang, I. W., Lurje, I., Lurje, G., Knosalla, C., Schoenrath, F., Tacke, F. & Engelmann, C. Semin Liver Dis (2024). https://www.ncbi.nlm.nih.gov/pubmed/39053507
Lysozyme 1 Inflamed CCR2(+) Macrophages Promote Obesity-Induced Cardiac Dysfunction. Zhang, L., Han, H., Xu, A., Sathe, A., Fu, S., Zhao, J., Cai, W., Yang, Y., Liu, J., Bai, H., Ben, J., Zhu, X., Li, X., Yang, Q., Wang, Z., Gu, Y., Xing, C., Schiattarella, G. G., Cheng, S. Y., Zhang, H. & Chen, Q. Circ Res 135, 596-613 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39056179
CITED4 gene therapy protects against maladaptive cardiac remodeling after ischemia/reperfusion injury in mice. Lerchenmuller, C., Hastings, M. H., Rabolli, C. P., Betge, F., Roshan, M., Liu, L. X., Liu, X., Hess, C., Roh, J. D., Platt, C., Bezzerides, V., Busch, M., Katus, H. A., Frey, N., Most, P. & Rosenzweig, A. Mol Ther (2024). https://www.ncbi.nlm.nih.gov/pubmed/39066479
[Shortfalls of new data 2017-2020 in the German transplant registry]. Otto, G., Budde, K., Bara, C. & Gottlieb, J. Dtsch Med Wochenschr (2024). https://www.ncbi.nlm.nih.gov/pubmed/39059414
Quantifying and visualizing abdominal hemodynamics in patients with Fontan circulation by 4D phase-contrast flow magnetic resonance imaging at 1.5 T. Salehi Ravesh, M., Langguth, P., Moritz, J. D., Rinne, K., Harneit, P. L., Schulze-Nagel, J., Graessner, J., Uebing, A., Jansen, O., Both, M. & Hansen, J. H. Int J Cardiol 413, 132391 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39059472
Impulse initiation in engrafted pluripotent stem cell-derived cardiomyocytes can stimulate the recipient heart. Studemann, T., Schwarzova, B., Schneidewind, T., Geertz, B., von Bibra, C., Nehring, M., Rossinger, J., Wiegert, J. S., Eschenhagen, T. & Weinberger, F. Stem Cell Reports 19, 1053-1060 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39059379
Mechanical versus Biological Mitral Valve Replacement: Insights from Propensity Score Matching on Survival and Reoperation Rates. Feirer, N., Buchner, A., Weber, M., Lang, M., Dzilic, E., Amabile, A., Geirsson, A., Trenkwalder, T., Krane, M. & Vitanova, K. J Thorac Cardiovasc Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/39067811
An executive summary on the Global conceptual definition of Sarcopenia. Kirk, B., Cawthon, P. M., Arai, H., Avila-Funes, J. A., Barazzoni, R., Bhasin, S., Binder, E. F., Bruyere, O., Cederholm, T., Chen, L. K., Cooper, C., Duque, G., Fielding, R. A., Guralnik, J., Kiel, D. P., Landi, F., Reginster, J. Y., Sayer, A. A., Visser, M., von Haehling, S., Woo, J., Cruz-Jentoft, A. J. & Global Leadership Initiative in Sarcopenia, G. Aging Clin Exp Res 36, 153 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39066819
"Re-evaluation of variants of uncertain significance in patients with hereditary arrhythmogenic disorders". Martin, S., Jenewein, T., Geisen, C., Scheiper-Welling, S. & Kauferstein, S. BMC Cardiovasc Disord 24, 390 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39068400
Genomic privacy preservation in genome-wide association studies: taxonomy, limitations, challenges, and vision. Aherrahrou, N., Tairi, H. & Aherrahrou, Z. Brief Bioinform 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39073827
GWAS breakthroughs: mapping the journey from one locus to 393 significant CAD associations. Aherrahrou, R., Reinberger, T., Hashmi, S. & Erdmann, J. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/39073758
Publisher Correction: Quantitative flow ratio or angiography for the assessment of non-culprit lesions in acute coronary syndromes, a randomized trial. Ullrich-Daub, H., Olschewski, M., Schnorbus, B., Belhadj, K. A., Kohler, T., Vosseler, M., Munzel, T. & Gori, T. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39073452
Outcomes after transcatheter mitral valve implantation in valve-in-valve, valve-in-ring, and valve-in-mitral annular calcification. Alvarez-Covarrubias, H. A., Joner, M., Lutz, M., Xhepa, E., Mayr, N. P., Lachmann, M., Cassese, S., Rheude, T., Pellegrini, C., Kufner, S., Schunkert, H., Kastrati, A., Erlebach, M., Lange, R. & Ruge, H. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39077791
Impact of a dedicated cardiac protocol on diagnosis of infective endocarditis in patients undergoing [(18)F]-FDG-thoracic digital-PET/CT - Effects of expertise level. Notohamiprodjo, S., Scheidhauer, K., Eiber, M., Yakushev, I., Villagran Asiares, A., Kraus-Deuringer, J., Krebs-Fleischmann, H. W. A., Kleiner, S., Eggerstedt, R., Eglseder, B., Weber, W. A. & Nekolla, S. G. J Nucl Cardiol, 102010 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39074602
Self-supervised learning for improved calibrationless radial MRI with NLINV-Net. Blumenthal, M., Fantinato, C., Unterberg-Buchwald, C., Haltmeier, M., Wang, X. & Uecker, M. Magn Reson Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/39080844
Interventional closure of an iatrogenic LAA-perforation by means of a PFO-occluder. Genske, F., Marquetand, C., Schmidt, T., Stiermaier, T. & Eitel, I. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/39082843
GPT-4 Analysis of MRI Reports in Suspected Myocarditis: A Multicenter Study. Kaya, K., Gietzen, C., Hahnfeldt, R., Zoubi, M., Emrich, T., Halfmann, M. C., Sieren, M. M., Elser, Y., Krumm, P., Brendel, J. M., Nikolaou, K., Haag, N., Borggrefe, J., Kruchten, R. V., Muller-Peltzer, K., Ehrengut, C., Denecke, T., Hagendorff, A., Goertz, L., Gertz, R. J., Bunck, A. C., Maintz, D., Persigehl, T., Lennartz, S., Luetkens, J. A., Jaiswal, A., Iuga, A. I., Pennig, L. & Kottlors, J. J Cardiovasc Magn Reson, 101068 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39079602
A powerful safety net: Social support moderates the association of quality of life deficits with suicidal ideation in long-term childhood cancer survivors. Schwinn, T., Hirschmiller, J., Brahler, E., Merzenich, H., Faber, J., Wild, P. S., Beutel, M. E. & Ernst, M. J Psychosoc Oncol, 1-18 (2024). https://www.ncbi.nlm.nih.gov/pubmed/39083714
Effects of high- versus low-intensity lipid-lowering treatment in patients undergoing serial coronary computed tomography angiography: results of the multi-center LOCATE study. Weichsel, L., Andre, F., Renker, M., Breitbart, P., Overhoff, D., Beer, M., Giesen, A., Vattay, B., Buss, S., Marwan, M., Schlett, C. L., Giannopoulos, A. A., Kelle, S., Frey, N., Korosoglou, G. & Investigators, L. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/39080016
Juni
Paper of the Month
Prediction of diagnosis and diastolic filling pressure by AI-enhanced cardiac MRI: a modelling study of hospital data
DZHK-Autor:innen: David Hermann Lehmann, Bruna Gomes, Ali Amr, Christoph Reich, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Jan Haas, Florian André, Sandy Engelhardt, Hugo A Katus, Norbert Frey, Benjamin Meder. The Lancet Digital Health.
Radiomics workflow definition & challenges - German priority program 2177 consensus statement on clinically applied radiomics. Floca, R., Bohn, J., Haux, C., Wiestler, B., Zollner, F. G., Reinke, A., Weiss, J., Nolden, M., Albert, S., Persigehl, T., Norajitra, T., Baessler, B., Dewey, M., Braren, R., Buchert, M., Fallenberg, E. M., Galldiks, N., Gerken, A., Gotz, M., Hahn, H. K., Haubold, J., Haueise, T., Grosse Hokamp, N., Ingrisch, M., Iuga, A. I., Janoschke, M., Jung, M., Kiefer, L. S., Lohmann, P., Machann, J., Moltz, J. H., Nattenmuller, J., Nonnenmacher, T., Oerther, B., Othman, A. E., Peisen, F., Schick, F., Umutlu, L., Wichtmann, B. D., Zhao, W., Caspers, S., Schlemmer, H. P., Schlett, C. L., Maier-Hein, K. & Bamberg, F. Insights Imaging 15, 124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38825600
Type 1 Myocardial Infarction in Patients With Acute Ischemic Stroke. Nolte, C. H., von Rennenberg, R., Litmeier, S., Leistner, D. M., Szabo, K., Baumann, S., Mengel, A., Michalski, D., Siepmann, T., Blankenberg, S., Petzold, G. C., Dichgans, M., Katus, H., Pieske, B., Regitz-Zagrosek, V., Braemswig, T. B., Rangus, I., Pepic, A., Vettorazzi, E., Zeiher, A. M., Scheitz, J. F., Wegscheider, K., Landmesser, U. & Endres, M. JAMA Neurol 81, 703-711 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38829625
Biological basis and treatment of frailty and sarcopenia. Sato, R., Vatic, M., Peixoto da Fonseca, G. W., Anker, S. D. & von Haehling, S. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38828887
The significant impact of experimental variables on the gut microbiome. Zakarauskas-Seth, B. I. & Sawamiphak, S. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38830015
[Acute ischemic stroke and troponin elevation: update of the Mannheim clinical algorithm]. Becker, L., Alonso, A., Kruska, M., Baumann, S., Grassl, N., Lesch, H., Eisele, P., Sieburg, T., Behnes, M., Schupp, T., Kayed, H., Platten, M., Duerschmied, D., Szabo, K., Akin, I. & Fastner, C. Inn Med (Heidelb) 65, 830-839 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38831047
Standardisation in Paediatric Echocardiography Reporting and Critical Interpretation of Measurements, Functional Parameters and Prediction Scores. A Clinical Consensus Statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC and the Association for European Paediatric and Congenital Cardiology (AEPC). Cantinotti, M., Di Salvo, G., Voges, I., Raimondi, F., Greil, G., Ortiz Garrido, A., Bharucha, T., Grotenhuis, H. B., Kostenberger, M., Bonnello, B., Miller, O. & McMahon, C. J. Eur Heart J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38833586
Transient stabilization of human cardiovascular progenitor cells from hPSCs in vitro reflects stage-specific heart development in vivo. Emiliano, B., Dorothee, B., Iyer, L. M., Dorota, Z., Nina, F., Michael, M., Lucas, L., David, G., Nadine, S., Andreas, L., Wunder, J., Annika, F., Lika, D., Sebra, R., Axel, S., Alexander, G., Nicole, D., Gergana, D., Alessandra, M., Zelarayan, L. C., Salim, A. S. & Robert, Z. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38836637
A Man in His 50s With Dyspnea and Eosinophilia. Jakobs, K. C., Rauch, U. & Heidecker, B. JAMA Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38837171
Mapping the interplay of atrial fibrillation, brain structure, and cognitive dysfunction. Petersen, M., Chevalier, C., Naegele, F. L., Ingwersen, T., Omidvarnia, A., Hoffstaedter, F., Patil, K., Eickhoff, S. B., Schnabel, R. B., Kirchhof, P., Schlemm, E., Cheng, B., Thomalla, G. & Jensen, M. Alzheimers Dement 20, 4512-4526 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38837525
Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner. Wang, Y., Li, G., Chen, B., Shakir, G., Volz, M., van der Vorst, E. P. C., Maas, S. L., Geiger, M., Jethwa, C., Bartelt, A., Li, Z., Wettich, J., Sachs, N., Maegdefessel, L., Nazari Jahantigh, M., Hristov, M., Lacy, M., Lutz, B., Weber, C., Herzig, S., Guillamat Prats, R. & Steffens, S. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38838211
Unloading in cardiogenic shock: the rationale and current evidence. Besch, L. & Schrage, B. Curr Opin Crit Care 30, 379-384 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38841993
Association between socioeconomic and psychosocial factors with use of interventional and surgical treatments and outcomes in patients with myocardial infarction - Inpatient data of the largest European health care system. Hahad, O., Hobohm, L., Al-Kindi, S., Schmitt, V. H., Kazemi-Asrar, F., Gilan, D., Petrowski, K., Gori, T., Wild, P., Lieb, K., Daiber, A., Lurz, P., Munzel, T. & Keller, K. Eur J Intern Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839532
Left Atrial Reservoir Strain and Recurrence of Atrial Fibrillation Following De-Novo Pulmonary Vein Isolation - Results of the ASTRA-AF Pilot Study. Knappe, D., Vogler, J., Weimann, J., Banas, V., Obergassel, J., Yildirim, S., Memenga, F., Senftinger, J., Keil, L., Ismaili, D., Nies, M., Rillig, A., Willems, S., Blankenberg, S., Kirchhof, P., Metzner, A. & Sinning, C. Circ J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839350
Routine postdilation after 23 mm Sapien 3 Ultra implantation in the aortic position. Leone, P. P., Sturla, M., Spring, A. M., Echarte-Morales, J., Scotti, A., Ludwig, S., Coisne, A., Slipczuk, L., Assafin, M., Chau, M., Ho, E. C., Granada, J. F. & Latib, A. Catheter Cardiovasc Interv (2024). https://www.ncbi.nlm.nih.gov/pubmed/38841916
Inhibition of autophagy prevents cardiac dysfunction at early stages of cardiomyopathy in Bag3-deficient hearts. Maroli, G., Schanzer, A., Gunther, S., Garcia-Gonzalez, C., Rupp, S., Schlierbach, H., Chen, Y., Graumann, J., Wietelmann, A., Kim, J. & Braun, T. J Mol Cell Cardiol 193, 53-66 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38838815
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction. Schormair, B., Zhao, C., Bell, S., Didriksen, M., Nawaz, M. S., Schandra, N., Stefani, A., Hogl, B., Dauvilliers, Y., Bachmann, C. G., Kemlink, D., Sonka, K., Paulus, W., Trenkwalder, C., Oertel, W. H., Hornyak, M., Teder-Laving, M., Metspalu, A., Hadjigeorgiou, G. M., Polo, O., Fietze, I., Ross, O. A., Wszolek, Z. K., Ibrahim, A., Bergmann, M., Kittke, V., Harrer, P., Dowsett, J., Chenini, S., Ostrowski, S. R., Sorensen, E., Erikstrup, C., Pedersen, O. B., Topholm Bruun, M., Nielsen, K. R., Butterworth, A. S., Soranzo, N., Ouwehand, W. H., Roberts, D. J., Danesh, J., Burchell, B., Furlotte, N. A., Nandakumar, P., andMe Research, T., group, D. E. S. I. R. s., Earley, C. J., Ondo, W. G., Xiong, L., Desautels, A., Perola, M., Vodicka, P., Dina, C., Stoll, M., Franke, A., Lieb, W., Stewart, A. F. R., Shah, S. H., Gieger, C., Peters, A., Rye, D. B., Rouleau, G. A., Berger, K., Stefansson, H., Ullum, H., Stefansson, K., Hinds, D. A., Di Angelantonio, E., Oexle, K. & Winkelmann, J. Nat Genet 56, 1090-1099 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839884
Gender-specific aspects of socialisation and risk of cardiovascular disease among community-dwelling older adults: a prospective cohort study using machine learning algorithms and a conventional method. Teshale, A. B., Htun, H. L., Owen, A. J., Ryan, J., Baker, J. R., Vered, M., Reid, C. M., Woods, R. L., Berk, M., Tonkin, A., Neumann, J. T., Kilkenny, M. F., Phyo, A. Z. Z., Nelson, M. R., Stocks, N., Britt, C. & Freak-Poli, R. J Epidemiol Community Health (2024). https://www.ncbi.nlm.nih.gov/pubmed/38839108
Atrial fibrillation after patent foramen ovale closure in patients with embolic stroke of undetermined source. von Falkenhausen, A. S., Keidel, L. M., Wischmann, J., Hoglinger, G., Massberg, S., Kaab, S., Kellert, L. & Sinner, M. F. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38842105
Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure: Baseline characteristics of patients in the RESHAPE-HF2 trial and comparison to COAPT and MITRA-FR trials. Anker, S. D., Friede, T., von Bardeleben, R. S., Butler, J., Khan, M. S., Diek, M., Heinrich, J., Geyer, M., Placzek, M., Ferrari, R., Abraham, W. T., Alfieri, O., Auricchio, A., Bayes-Genis, A., Cleland, J. G. F., Filippatos, G., Gustafsson, F., Haverkamp, W., Kelm, M., Kuck, K. H., Landmesser, U., Maggioni, A. P., Metra, M., Ninios, V., Petrie, M. C., Rassaf, T., Ruschitzka, F., Schafer, U., Schulze, P. C., Spargias, K., Vahanian, A., Zamorano, J. L., Zeiher, A., Karakas, M., Koehler, F., Lainscak, M., Oner, A., Mezilis, N., Theofilogiannakos, E. K., Ninios, I., Chrissoheris, M., Kourkoveli, P., Papadopoulos, K., Smolka, G., Wojakowski, W., Reczuch, K., Pinto, F. J., Zmudka, K., Kalarus, Z., Adamo, M., Santiago-Vacas, E., Ruf, T. F., Gross, M., Tongers, J., Hasenfuss, G., Schillinger, W. & Ponikowski, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38847420
Platelet mass cytometry reveals dysregulation of prothrombotic pathways in essential thrombocythemia. Dill, V., Kirmes, K., Han, J., Klug, M., Rosenbaum, M., Viggiani, G., von Scheidt, M., List, M., Herhaus, P., Ruland, J., Bassermann, F., Laugwitz, K. L., Gotze, K. S., Jost, P. J., Jilg, S., Bloxham, C. J., Raake, P. W. J., Bernlochner, I. & Bongiovanni, D. Platelets 35, 2358244 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38845541
Oral anticoagulation in patients with left ventricular thrombus - a systematic review and meta-analysis. Haller, P. M., Kazem, N., Agewall, S., Borghi, C., Ceconi, C., Dobrev, D., Cerbai, E., Grove, E. L., Kaski, J. C., Lewis, B. S., Niessner, A., Rocca, B., Rosano, G., Savarese, G., Schnabel, R., Semb, A. G., Sossalla, S., Wassmann, S. & Sulzgruber, P. Eur Heart J Cardiovasc Pharmacother (2024). https://www.ncbi.nlm.nih.gov/pubmed/38845369
Simulation of thoracic endovascular aortic repair in a perfused patient-specific model of type B aortic dissection. Mohl, L., Karl, R., Hagedorn, M. N., Runz, A., Skornitzke, S., Toelle, M., Bergt, C. S., Hatzl, J., Uhl, C., Bockler, D., Meisenbacher, K. & Engelhardt, S. Int J Comput Assist Radiol Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38848033
Fronto-thalamic networks and the left ventral thalamic nuclei play a key role in aphasia after thalamic stroke. Rangus, I., Rios, A. S., Horn, A., Fritsch, M., Khalil, A., Villringer, K., Udke, B., Ihrke, M., Grittner, U., Galinovic, I., Al-Fatly, B., Endres, M., Kufner, A. & Nolte, C. H. Commun Biol 7, 700 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38849518
Impact of Patient-Prosthesis Mismatch on Long-term Outcomes After Aortic Valve Replacement. Graser, M., Bleiziffer, S., Zittermann, A., Mayr, B., Sideris, K., Puluca, N., Krane, M. & Prinzing, A. Ann Thorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38851414
Right heart failure with left ventricular assist devices: Preoperative, perioperative and postoperative management strategies. A clinical consensus statement of the Heart Failure Association (HFA) of the ESC. Adamopoulos, S., Bonios, M., Ben Gal, T., Gustafsson, F., Abdelhamid, M., Adamo, M., Bayes-Genis, A., Bohm, M., Chioncel, O., Cohen-Solal, A., Damman, K., Di Nora, C., Hashmani, S., Hill, L., Jaarsma, T., Jankowska, E., Lopatin, Y., Masetti, M., Mehra, M. R., Milicic, D., Moura, B., Mullens, W., Nalbantgil, S., Panagiotou, C., Piepoli, M., Rakisheva, A., Ristic, A., Rivinius, R., Savarese, G., Thum, T., Tocchetti, C. G., Tops, L. F., Van Laake, L. W., Volterrani, M., Seferovic, P., Coats, A., Metra, M. & Rosano, G. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38853659
Transcatheter aortic valve replacement in patients with severe aortic valve stenosis and concomitant mitral valve regurgitation - 5 years follow-up. Henrique Rangel, R., Christoph Voran, J., Seoudy, H., Villinger, T., Lutter, G., Puehler, T., Kreidel, F., Frank, J., Salem, M., Frank, D. & Saad, M. Int J Cardiol Heart Vasc 53, 101416 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38854408
Pilot study to evaluate the use of remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): study protocol for a randomised controlled trial delivered in two tertiary cardiac centres in the UK. Khan, N., Steeds, R. P., Kyte, D., Fabritz, L., Collis, P., Chua, W., Stubbs, C., Mehta, S., Sun, Y., Nulty, M., Kirkham, K. & Cotton, J. M. BMJ Open 14, e086587 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38858149
Incidence, Implications, and Management of Sense-B-Noise Failure in Subcutaneous Cardioverter-Defibrillator Patients: insights from a large Multicenter Registry. Wormann, J., Strik, M., Jurisic, S., Stout, K., Elrefai, M., Becher, N., Schaer, B., van Stipdonk, A., Srinivasan, N. T., Ploux, S., Breitenstein, A., Kron, J., Roberts, P. R., Toennis, T., Linz, D., Dulai, R., Hermes-Laufer, J., Koneru, J., Erkuner, O., Dittrich, S., van den Bruck, J. H., Schipper, J. H., Sultan, A., Rosenberger, K. D., Steven, D. & Luker, J. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38861398
Non-invasive assessment of left ventricular contractility by myocardial work index in veno-arterial membrane oxygenation patients: rationale and design of the MIX-ECMO multicentre observational study. Lakatos, B. K., Ladanyi, Z., Fabian, A., Ehrenberger, R., Turschl, T., Bagyura, Z., Evrard, B., Vandroux, D., Goudelin, M., Lindner, S., Britsch, S., Durschmied, D., Zima, E., Csikos, G. R., Turoczi, Z., Soltesz, A., Nemeth, E., Kovacs, A., Edes, F. I. & Merkely, B. Front Cardiovasc Med 11, 1399874 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38863897
Central obesity and fat-free mass are associated with a larger spleen volume in the general population. Mousa, M. F. M., Naeem, M., Bibi, S., Bulow, R., Bahls, M., Siewert-Markus, U., Topfer, P., Aghdassi, A., Khattak, M. N. K., Volzke, H., Markus, M. R. & Ittermann, T. Ups J Med Sci 129 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38863728
Reduced olfactory bulb volume accompanies olfactory dysfunction after mild SARS-CoV-2 infection. Petersen, M., Becker, B., Schell, M., Mayer, C., Naegele, F. L., Petersen, E., Twerenbold, R., Thomalla, G., Cheng, B., Betz, C. & Hoffmann, A. S. Sci Rep 14, 13396 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38862636
Targeting obesity for therapeutic intervention in heart failure patients. Sato, R. & von Haehling, S. Expert Rev Cardiovasc Ther 22, 217-230 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38864827
Diagnostic value of left ventricular layer strain and specific regional strain patterns in cardiac amyloidosis and Fabry disease. Steudel, T., Barzen, G., Frumkin, D., Romero-Dorta, E., Spethmann, S., Hindricks, G., Stangl, K., Knebel, F., Heidecker, B., Canaan-Kuhl, S., Pernice, H. F., Hahn, K., Mattig, I. & Brand, A. Eur Heart J Open 4, oeae041 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38863522
Noncalcific Transcatheter Heart Valve Dysfunction: Novel Dogma or Simple Precursor? Joner, M. & Xhepa, E. JACC Cardiovasc Interv 17, 1352-1355 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38866458
Impact of telemedical management on hospitalization and mortality in heart failure patients with diabetes: a post-hoc subgroup analysis of the TIM-HF2 trial. Koehler, F., Koehler, J., Bramlage, P., Vettorazzi, E., Wegscheider, K., Lezius, S., Spethmann, S., Iakoubov, R., Vijayan, A., Winkler, S., Melzer, C., Schutt, K., Dessapt-Baradez, C., Paar, W. D., Koehler, K. & Muller-Wieland, D. Cardiovasc Diabetol 23, 198 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38867198
Hydrodynamic Assessment of Explanted Degenerated Transcatheter Aortic Valves: Novel Insights Into Noncalcific and Calcific Mechanisms. Sathananthan, J., Nigade, A., Meier, D., Navarro, D., Spencer, J., Lai, A., Gill, H., Pirelli, L., Webb, J. G., Wood, D. A., Lutter, G., Puehler, T., Tang, G. H. L., Fukuhara, S. & Sellers, S. L. JACC Cardiovasc Interv 17, 1340-1351 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38866457
Spoiled for Choice: P2Y(12) Receptor Inhibition in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention. Sibbing, D., Massberg, S. & Rizas, K. D. JACC Cardiovasc Interv 17, 1371-1373 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38866459
Associations between multiple neurological biomarkers and distal sensorimotor polyneuropathy: KORA F4/FF4 study. Herder, C., Thorand, B., Strom, A., Rathmann, W., Heier, M., Koenig, W., Morrison, H., Ziegler, D., Roden, M., Peters, A., Bonhof, G. J. & Maalmi, H. Diabetes Metab Res Rev 40, e3807 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38872492
Pathomechanistic Synergy Between Particulate Matter and Traffic Noise-Induced Cardiovascular Damage and the Classical Risk Factor Hypertension. Kuntic, M., Hahad, O., Al-Kindi, S., Oelze, M., Lelieveld, J., Daiber, A. & Munzel, T. Antioxid Redox Signal (2024). https://www.ncbi.nlm.nih.gov/pubmed/38874533
Lower muscular strength is associated with greater liver fat content and higher serum liver enzymes-"The Sedentary's Liver" The Study of Health in Pomerania. Mayer, C., Ittermann, T., Schipf, S., Gross, S., Kim, S., Schielke, J., Bulow, R., Kuhn, J. P., Lerch, M. M., Volzke, H., Felix, S. B., Bahls, M., Targher, G., Dorr, M. & Markus, M. R. P. Eur J Sport Sci 24, 824-833 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38874978
Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension. Zhang, Q., Yaoita, N., Tabuchi, A., Liu, S., Chen, S. H., Li, Q., Hegemann, N., Li, C., Rodor, J., Timm, S., Laban, H., Finkel, T., Stevens, T., Alvarez, D. F., Erfinanda, L., de Perrot, M., Kucherenko, M. M., Knosalla, C., Ochs, M., Dimmeler, S., Korff, T., Verma, S., Baker, A. H. & Kuebler, W. M. Circulation 150, 466-487 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38873770
CMR-based cardiac phenotyping in different forms of heart failure. Lange, T., Backhaus, S. J., Schulz, A., Hashemi, D., Evertz, R., Kowallick, J. T., Hasenfuss, G., Kelle, S. & Schuster, A. Int J Cardiovasc Imaging 40, 1585-1596 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38878148
STING orchestrates the neuronal inflammatory stress response in multiple sclerosis. Woo, M. S., Mayer, C., Binkle-Ladisch, L., Sonner, J. K., Rosenkranz, S. C., Shaposhnykov, A., Rothammer, N., Tsvilovskyy, V., Lorenz, S. M., Raich, L., Bal, L. C., Vieira, V., Wagner, I., Bauer, S., Glatzel, M., Conrad, M., Merkler, D., Freichel, M. & Friese, M. A. Cell (2024). https://www.ncbi.nlm.nih.gov/pubmed/38878778
Editorial: Proteostasis in cardiac health and disease. Buhringer, H., Doroudgar, S., Wang, X., Frey, N. & Rangrez, A. Y. Front Mol Biosci 11, 1433721 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38882607
Personalized nutritional prevention for Lp(a): PUFAs seem to do the job. Lehnert, K., Konemann, S. & Bahls, M. Atherosclerosis 395, 117597 (2024). www.ncbi.nlm.nih.gov/pubmed/38880705
Occurrence of Premature Battery Depletion in a Large Multicenter Registry of Subcutaneous Cardioverter-Defibrillator Patients. Wormann, J., Strik, M., Jurisic, S., Stout, K., Elrefai, M., Becher, N., Schaer, B., van Stipdonk, A., Srinivasan, N. T., Ploux, S., Breitenstein, A., Kron, J., Roberts, P. R., Toennis, T., Linz, D., Dulai, R., Hermes-Laufer, J., Koneru, J., Erkuner, O., Dittrich, S., van den Bruck, J. H., Schipper, J. H., Sultan, A., Rosenberger, K. D., Steven, D. & Luker, J. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38885309
Cardiac fibrosis as a predictor for sudden cardiac death after transcatheter aortic valve implantation. Alnour, F., Beuthner, B. E., Hakroush, S., Topci, R., Vogelgesang, A., Lange, T., Seidler, T., Kutschka, I., Toischer, K., Schuster, A., Jacobshagen, C., Leha, A., Zabel, M., Hasenfuss, G., Puls, M. & Zeisberg, E. M. EuroIntervention20, e760-e769 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38887885
Perfect Match: Radiomics and Artificial Intelligence in Cardiac Imaging. Baessler, B., Engelhardt, S., Hekalo, A., Hennemuth, A., Hullebrand, M., Laube, A., Scherer, C., Tolle, M. & Wech, T. Circ Cardiovasc Imaging 17, e015490 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38889216
Epstein-Barr Virus Lytic Transcripts Correlate with the Degree of Myocardial Inflammation in Heart Failure Patients. Baumeier, C., Harms, D., Altmann, B., Aleshcheva, G., Wiegleb, G., Bock, T., Escher, F. & Schultheiss, H. P. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38892033
Backwash Maneuver for HeartMate3 Inflow Thrombosis: Experience From Two Cases. Cholevas, N., Hoermandinger, C., Just, I. A., Politis, N., Falk, V., Potapov, E. & Schoenrath, F. ASAIO J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896847
Catecholamine induces endothelial dysfunction via Angiotensin II and intermediate conductance calcium activated potassium channel. Fan, X., Yang, G., Yang, Z., Uhlig, S., Sattler, K., Bieback, K., Hamdani, N., El-Battrawy, I., Duerschmied, D., Zhou, X. & Akin, I. Biomed Pharmacother 177, 116928 (2024). www.ncbi.nlm.nih.gov/pubmed/38889637
Na(V)1.8 as Proarrhythmic Target in a Ventricular Cardiac Stem Cell Model. Hartmann, N., Knierim, M., Maurer, W., Dybkova, N., Zeman, F., Hasenfuss, G., Sossalla, S. & Streckfuss-Bomeke, K. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38892333
Long-term risk factor management and adverse events in patients with early-onset myocardial infarction-a "real-world" study. Kerniss, H., Marin, L. A. M., Clemens, K., Litfin, C., Seidel-Sarpong, A., Hanses, U., Ruhle, S., Schmucker, J., Osteresch, R., Fach, A., Eitel, I., Hambrecht, R. & Wienbergen, H. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896124
Gait Variability as a Potential Motor Marker of Cerebellar Disease-Relationship between Variability of Stride, Arm Swing and Trunk Movements, and Walking Speed. Kroneberg, D., Numann, A., Minnerop, M., Ronnefarth, M., Endres, M., Kuhn, A. A., Paul, F., Doss, S., Solbrig, S., Elshehabi, M., Maetzler, W. & Schmitz-Hubsch, T. Sensors (Basel) 24 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38894268
Electrophysiological Effects of the Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitor Dapagliflozin on Human Cardiac Potassium Channels. Muller, M. E., Petersenn, F., Hackbarth, J., Pfeiffer, J., Gampp, H., Frey, N., Lugenbiel, P., Thomas, D. & Rahm, A. K. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38891889
3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models. Saleem, H. N., Ignatyeva, N., Stuut, C., Jakobs, S., Habeck, M. & Ebert, A. Cells 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38891055
Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. Seferovic, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschope, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalic, N., Ceriello, A., Dohner, W., Ristic, A., Milinkovic, I., Seferovic, J., Cosentino, F., Metra, M. & Coats, A. J. S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896048
Functional Mitral Valve Regurgitation: Mitral Valve Repair or Replacement? Our "Road Map" for the Appropriate Strategy. Sideris, K., Burri, M., Mayr, A., Voss, S., Vitanova, K., Prinzing, A., Voss, B., Amabile, A., Geirsson, A., Krane, M. & Guenzinger, R. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38892978
Prevention and rehabilitation after heart transplantation: A clinical consensus statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a section of ESOT. Simonenko, M., Hansen, D., Niebauer, J., Volterrani, M., Adamopoulos, S., Amarelli, C., Ambrosetti, M., Anker, S. D., Bayes-Genis, A., Gal, T. B., Bowen, T. S., Cacciatore, F., Caminiti, G., Cavarretta, E., Chioncel, O., Coats, A. J. S., Cohen-Solal, A., D'Ascenzi, F., de Pablo Zarzosa, C., Gevaert, A. B., Gustafsson, F., Kemps, H., Hill, L., Jaarsma, T., Jankowska, E., Joyce, E., Krankel, N., Lainscak, M., Lund, L. H., Moura, B., Nytroen, K., Osto, E., Piepoli, M., Potena, L., Rakisheva, A., Rosano, G., Savarese, G., Seferovic, P. M., Thompson, D. R., Thum, T. & Van Craenenbroeck, E. M. Eur J Prev Cardiol31, 1385-1399 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38894688
Citrate-Buffered, Magnesium-Enriched Dialysate on Calcification Propensity in Hemodialysis Patients - The CitMag Study. Cejka, D., Thiem, U., Blinzler, E., Machacek, J., Voelkl, J., Smith, E. R., Pasch, A. & Haller, M. C. Kidney Int Rep 9, 1765-1773 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38899177
Cardiopulmonary Exercise Test and Daily Physical Activity in Pediatric Congenital Heart Disease: An Exploratory Analysis. Hock, J., Brudy, L., Willinger, L., Hager, A., Ewert, P., Oberhoffer-Fritz, R. & Muller, J. Am J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38897267
Physician-directed patient self-management in heart failure using left atrial pressure: Interim insights from the VECTOR-HF I and IIa studies. Meerkin, D., Perl, L., Hasin, T., Petriashvili, S., Kurashvili, L., Metreveli, M., Ince, H., Feickert, S., Habib, M., Caspi, O., Jonas, M., Amat-Santos, I. J., Bayes-Genis, A., Codina, P., Koren, O., Frydman, S., Pachino, R. M., Anker, S. D., Abraham, W. T., on behalf of the, V.-H. I. & Investigators, I. I. T. Eur J Heart Fail 26, 1814-1823 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38899626
The effect of a selenium-based anti-inflammatory strategy on postoperative functional recovery in high-risk cardiac surgery patients - A nested sub-study of the sustain CSX trial. Ott, S., Lee, Z. Y., Muller-Wirtz, L. M., Cangut, B., Roessler, J., Patterson, W., Thomas, C. M., Bekele, B. M., Windpassinger, M., Lobdell, K., Grant, M. C., Arora, R. C., Engelman, D. T., Fremes, S., Velten, M., O'Brien, B., Ruetzler, K., Heyland, D. K. & Stoppe, C. Life Sci 351, 122841 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38897349
Midterm results after aortic valve neocuspidization. Prinzing, A., Boehm, J., Burri, M., Schreyer, J., Lange, R. & Krane, M. JTCVS Tech 25, 35-42 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38899113
Childhood maltreatment and risk of metabolic dysfunction-associated steatotic liver disease - Evidence of sex-specific associations in the general population. Siewert-Markus, U., Ittermann, T., Klinger-Konig, J., Grabe, H. J., Stracke, S., Volzke, H., Targher, G., Dorr, M., Markus, M. R. P. & Topfer, P. J Psychosom Res183, 111829 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38896985
Incidence and Prediction of Anoxic Brain Injury in Concomitant Cardiac Arrest and Cardiogenic Shock. Besch, L., Weimann, J., Jentzer, J., Beer, B., Dettling, A., Sundermeyer, J., Kirchhof, P., Blankenberg, S., Westermann, D. & Schrage, B. JACC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38904645
Correlation of diaphragm thickening fraction and oesophageal pressure swing in non-invasive ventilation of healthy subjects. Lindner, S., Hoermann, C., Teichert, J., Ziyadova, S., Michels-Zetsche, J. D., Neetz, B., Herth, F. J. F., Duerschmied, D. & Britsch, S. BMC Pulm Med 24, 289 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38902702
The role of concomitant coronary artery bypass grafting in acute type a aortic dissection complicated by coronary malperfusion. Pitts, L., Kofler, M., Montagner, M., Heck, R., Dominik Kurz, S., Sundermann, S., Falk, V. & Kempfert, J. Eur J Cardiothorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38905500
Intergenic risk variant rs56258221 skews the fate of naive CD4(+) T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis. Poch, T., Bahn, J., Casar, C., Krause, J., Evangelakos, I., Gilladi, H., Kunzmann, L. K., Laschtowitz, A., Iuso, N., Schafer, A. M., Liebig, L. A., Steinmann, S., Sebode, M., Folseraas, T., Engesaeter, L. K., Karlsen, T. H., Franke, A., Hubner, N., Schlein, C., Galun, E., Huber, S., Lohse, A. W., Gagliani, N., Schwinge, D. & Schramm, C. Cell Rep Med 5, 101620 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38901430
Small conductance calcium-activated potassium channel contributes to stress induced endothelial dysfunctions. Yang, Z., Li, Y., Huang, M., Li, X., Fan, X., Yan, C., Meng, Z., Liao, B., Hamdani, N., El-Battrawy, I., Yang, X., Zhou, X. & Akin, I. Microvasc Res 155, 104699 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38901735
Ferroptosis in health and disease. Berndt, C., Alborzinia, H., Amen, V. S., Ayton, S., Barayeu, U., Bartelt, A., Bayir, H., Bebber, C. M., Birsoy, K., Bottcher, J. P., Brabletz, S., Brabletz, T., Brown, A. R., Brune, B., Bulli, G., Bruneau, A., Chen, Q., DeNicola, G. M., Dick, T. P., Distefano, A., Dixon, S. J., Engler, J. B., Esser-von Bieren, J., Fedorova, M., Friedmann Angeli, J. P., Friese, M. A., Fuhrmann, D. C., Garcia-Saez, A. J., Garbowicz, K., Gotz, M., Gu, W., Hammerich, L., Hassannia, B., Jiang, X., Jeridi, A., Kang, Y. P., Kagan, V. E., Konrad, D. B., Kotschi, S., Lei, P., Le Tertre, M., Lev, S., Liang, D., Linkermann, A., Lohr, C., Lorenz, S., Luedde, T., Methner, A., Michalke, B., Milton, A. V., Min, J., Mishima, E., Muller, S., Motohashi, H., Muckenthaler, M. U., Murakami, S., Olzmann, J. A., Pagnussat, G., Pan, Z., Papagiannakopoulos, T., Pedrera Puentes, L., Pratt, D. A., Proneth, B., Ramsauer, L., Rodriguez, R., Saito, Y., Schmidt, F., Schmitt, C., Schulze, A., Schwab, A., Schwantes, A., Soula, M., Spitzlberger, B., Stockwell, B. R., Thewes, L., Thorn-Seshold, O., Toyokuni, S., Tonnus, W., Trumpp, A., Vandenabeele, P., Vanden Berghe, T., Venkataramani, V., Vogel, F. C. E., von Karstedt, S., Wang, F., Westermann, F., Wientjens, C., Wilhelm, C., Wolk, M., Wu, K., Yang, X., Yu, F., Zou, Y. & Conrad, M. Redox Biol 75, 103211 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38908072
Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation. Fakuade, F. E., Hubricht, D., Moller, V., Sobitov, I., Liutkute, A., Doring, Y., Seibertz, F., Gerloff, M., Pronto, J. R. D., Haghighi, F., Brandenburg, S., Alhussini, K., Ignatyeva, N., Bonhoff, Y., Kestel, S., El-Essawi, A., Jebran, A. F., Grossmann, M., Danner, B. C., Baraki, H., Schmidt, C., Sossalla, S., Kutschka, I., Bening, C., Maack, C., Linke, W. A., Heijman, J., Lehnart, S. E., Kensah, G., Ebert, A., Mason, F. E. & Voigt, N. Circulation 150, 544-559 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38910563
Functional characterization of PI3K C2 domain mutations detected in breast cancer circulating tumor cells and metastatic cells. Smit, D. J., Brauer, H., Horn, S., Yigit, G., Haider, M. T., Pogenberg, V., Schumacher, U., Pantel, K. & Jucker, M. Cell Signal, 111270 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38909932
Aging is associated with an insufficient early inflammatory response of lung endothelial cells in SARS-CoV-2 infection. Subramaniam, S., Kenney, D., Jayaraman, A., O'Connell, A. K., Walachowski, S., Montanaro, P., Reinhardt, C., Colucci, G., Crossland, N. A., Douam, F. & Bosmann, M. Front Immunol 15, 1397990 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38911865
Influence of donor age and donor-recipient age difference on intimal hyperplasia in pediatric patients with young and adult donors vs. adult patients after heart transplantation. Ulrich, S., Arnold, L., Michel, S., Tengler, A., Rosenthal, L., Hausleiter, J., Mueller, C. S., Schnabel, B., Stark, K., Rizas, K., Grabmaier, U., Mehilli, J., Jakob, A., Fischer, M., Birnbaum, J., Hagl, C., Massberg, S., Haas, N., Pozza, R. D. & Orban, M. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38913171
MRI-based adrenal gland volume is associated with cardiovascular alterations in individuals without prior cardiovascular disease. Askani, E., Rospleszcz, S., Lorbeer, R., Wintergerst, C., Muller-Peltzer, K., Nattenmuller, J., Hasic, D., von Kruchten, R., Kellner, E., Reisert, M., Rathmann, W., Peters, A., Schlett, C. L., Bamberg, F. & Storz, C. Sci Rep 14, 14664 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38918570
Cardiac aging: from hallmarks to therapeutic opportunities. Hastings, M. H., Zhou, Q., Wu, C., Shabani, P., Huang, S., Yu, X., Singh, A. P., Guseh, J. S., Li, H., Lerchenmuller, C. & Rosenzweig, A. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38918884
Towards Personalized TSH Reference Ranges: A Genetic and Population-Based Approach in Three Independent Cohorts. Kus, A., Sterenborg, R., Haug, E. B., Galesloot, T. E., Visser, W. E., Smit, J. W. A., Bednarczuk, T., Peeters, R. P., Asvold, B. O., Teumer, A. & Medici, M. Thyroid (2024). https://www.ncbi.nlm.nih.gov/pubmed/38919119
Open-ST: High-resolution spatial transcriptomics in 3D. Schott, M., Leon-Perinan, D., Splendiani, E., Strenger, L., Licha, J. R., Pentimalli, T. M., Schallenberg, S., Alles, J., Samut Tagliaferro, S., Boltengagen, A., Ehrig, S., Abbiati, S., Dommerich, S., Pagani, M., Ferretti, E., Macino, G., Karaiskos, N. & Rajewsky, N. Cell (2024). https://www.ncbi.nlm.nih.gov/pubmed/38917789
Management of cardiac sarcoidosis. Sharma, R., Kouranos, V., Cooper, L. T., Metra, M., Ristic, A., Heidecker, B., Baksi, J., Wicks, E., Merino, J. L., Klingel, K., Imazio, M., de Chillou, C., Tschope, C., Kuchynka, P., Petersen, S. E., McDonagh, T., Luscher, T. & Filippatos, G. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38923509
Sex differences in lipidomic and bile acid plasma profiles in patients with and without coronary artery disease. Bay, B., Fuh, M. M., Rohde, J., Worthmann, A., Gossling, A., Arnold, N., Koester, L., Lorenz, T., Blaum, C., Kirchhof, P., Blankenberg, S., Seiffert, M., Brunner, F. J., Waldeyer, C. & Heeren, J. Lipids Health Dis 23, 197 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38926753
Author Correction: Mechanisms controlling cellular and systemic iron homeostasis. Galy, B., Conrad, M. & Muckenthaler, M. Nat Rev Mol Cell Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38926532
Loss of Smooth Muscle Tenascin-X Inhibits Vascular Remodeling Through Increased TGF-beta Signaling. Liang, G., Lv, X. F., Huang, W., Jin, Y. J., Roquid, K. A., Kawase, H. & Offermanns, S. Arterioscler Thromb Vasc Biol 44, 1748-1763 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38934115
Tadalafil for Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction: A Randomized Controlled Phase 3 Study. Hoeper, M. M., Oerke, B., Wissmuller, M., Leuchte, H., Opitz, C., Halank, M., Seyfarth, H. J., Baldus, S., Bauersachs, J., Bohm, M., Ghofrani, H. A., Konstantinides, S., Olsson, K. M., Wachter, R., Lam, C. S. P., Aminossadati, B. & Rosenkranz, S. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38939948
Causes of death in patients with atrial fibrillation anticoagulated with rivaroxaban: a pooled analysis of XANTUS. Kirchhof, P., Haas, S., Amarenco, P., Turpie, A. G. G., Bach, M., Lambelet, M., Hess, S. & Camm, A. J. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38941511
Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: Rationale & design of the ARCHER trial. McNamara, D. M., Cooper, L. T., Arbel, Y., Bhimaraj, A., Bocchi, E., Friedrich, M. G., Kerneis, M., Liu, P., Parker, A. B., Smith, E. R., Tang, W. H. W., Torre-Amione, G., Tschope, C. & Group, A. S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38937900
Somatic symptom disorder symptoms in individuals at risk for heart failure: A cluster analysis with cross-sectional data from a population-based cohort study. Clifford, C., Twerenbold, R., Hartel, F., Lowe, B. & Kohlmann, S. J Psychosom Res 184, 111848 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38941711
Amyloid beta is associated with carotid wall echolucency and atherosclerotic plaque composition. Delialis, D., Georgiopoulos, G., Tual-Chalot, S., Angelidakis, L., Aivalioti, E., Mavraganis, G., Sopova, K., Argyris, A., Kostakou, P., Konstantaki, C., Papaioannou, M., Tsilimigras, D., Chatoupis, K., Zacharoulis, A. A., Galyfos, G., Sigala, F., Stellos, K. & Stamatelopoulos, K. Sci Rep 14, 14944 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38942831
Single-nucleus transcriptomics reveals adrenergic and STAT3 signaling in paradoxical low-flow low-gradient -specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment. Xu, X., Tan, X., Cui, B., Paul, N. B., Elkenani, M., Beuthner, B. E., Li, W., Mohamed, B. A., Schnelle, M., Puls, M., Zeisberg, E. M., Zeisberg, M., Beissbarth, T., Toischer, K. & Hasenfuss, G. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38943668
Plasma infrared fingerprinting with machine learning enables single-measurement multi-phenotype health screening. Eissa, T., Leonardo, C., Kepesidis, K. V., Fleischmann, F., Linkohr, B., Meyer, D., Zoka, V., Huber, M., Voronina, L., Richter, L., Peters, A. & Zigman, M. Cell Rep Med 5, 101625 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38944038
Mai
Paper of the Month
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes
DZHK-Autor:innen: Kami Pekayvaz, Christoph Gold, Rainer Kaiser, Sezer Akgöl, Tobias Petzold, Kathrin Saar, Philipp Mertins, Norbert Huebner, Steffen Massberg, Matthias Heinig, Leo Nicolai, Konstantin Stark. Nature Medicine.
All Three Supersystems-Nervous, Vascular, and Immune-Contribute to the Cortical Infarcts After Subarachnoid Hemorrhage. Dreier, J. P., Joerk, A., Uchikawa, H., Horst, V., Lemale, C. L., Radbruch, H., McBride, D. W., Vajkoczy, P., Schneider, U. C. & Xu, R. Transl Stroke Res (2024). https://pubmed.ncbi.nlm.nih.gov/38689162/
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Keaton, J. M., Kamali, Z., Xie, T., Vaez, A., Williams, A., Goleva, S. B., Ani, A., Evangelou, E., Hellwege, J. N., Yengo, L., Young, W. J., Traylor, M., Giri, A., Zheng, Z., Zeng, J., Chasman, D. I., Morris, A. P., Caulfield, M. J., Hwang, S. J., Kooner, J. S., Conen, D., Attia, J. R., Morrison, A. C., Loos, R. J. F., Kristiansson, K., Schmidt, R., Hicks, A. A., Pramstaller, P. P., Nelson, C. P., Samani, N. J., Risch, L., Gyllensten, U., Melander, O., Riese, H., Wilson, J. F., Campbell, H., Rich, S. S., Psaty, B. M., Lu, Y., Rotter, J. I., Guo, X., Rice, K. M., Vollenweider, P., Sundström, J., Langenberg, C., Tobin, M. D., Giedraitis, V., Luan, J., Tuomilehto, J., Kutalik, Z., Ripatti, S., Salomaa, V., Girotto, G., Trompet, S., Jukema, J. W., van der Harst, P., Ridker, P. M., Giulianini, F., Vitart, V., Goel, A., Watkins, H., Harris, S. E., Deary, I. J., van der Most, P. J., Oldehinkel, A. J., Keavney, B. D., Hayward, C., Campbell, A., Boehnke, M., Scott, L. J., Boutin, T., Mamasoula, C., Järvelin, M. R., Peters, A., Gieger, C., Lakatta, E. G., Cucca, F., Hui, J., Knekt, P., Enroth, S., De Borst, M. H., Polašek, O., Concas, M. P., Catamo, E., Cocca, M., Li-Gao, R., Hofer, E., Schmidt, H., Spedicati, B., Waldenberger, M., Strachan, D. P., Laan, M., Teumer, A., Dörr, M., Gudnason, V., Cook, J. P., Ruggiero, D., Kolcic, I., Boerwinkle, E., Traglia, M., Lehtimäki, T., Raitakari, O. T., Johnson, A. D., Newton-Cheh, C., Brown, M. J., Dominiczak, A. F., Sever, P. J., Poulter, N., Chambers, J. C., Elosua, R., Siscovick, D., Esko, T., Metspalu, A., Strawbridge, R. J., Laakso, M., Hamsten, A., Hottenga, J. J., de Geus, E., Morris, A. D., Palmer, C. N. A., Nolte, I. M., Milaneschi, Y., Marten, J., Wright, A., Zeggini, E., Howson, J. M. M., O'Donnell, C. J., Spector, T., Nalls, M. A., Simonsick, E. M., Liu, Y., van Duijn, C. M., Butterworth, A. S., Danesh, J. N., Menni, C., Wareham, N. J., Khaw, K. T., Sun, Y. V., Wilson, P. W. F., Cho, K., Visscher, P. M., Denny, J. C., Levy, D., Edwards, T. L., Munroe, P. B., Snieder, H. & Warren, H. R. Nat Genet 56, 778-791 (2024). https://pubmed.ncbi.nlm.nih.gov/38689001/
Long-term effectiveness and safety of edoxaban in patients with atrial fibrillation: 4-year data from the ETNA-AF-Europe study. Kirchhof, P., Bakhai, A., de Asmundis, C., de Groot, J. R., Deharo, J. C., Kelly, P., Lopez-de-Sa, E., Monteiro, P., Fronk, E. M., Lamparter, M., Laeis, P., Smolnik, R., Steffel, J., Waltenberger, J., Weiss, T. W. & De Caterina, R. Int J Cardiol 408, 132118 (2024). https://pubmed.ncbi.nlm.nih.gov/38697397/
Identification and outcomes of KDIGO-defined chronic kidney disease in 1.4 million U.S. Veterans with heart failure. Patel, S. S., Raman, V. K., Zhang, S., Deedwania, P., Zeng-Treitler, Q., Wu, W. C., Lam, P. H., Bakris, G., Moore, H., Heidenreich, P. A., Rangaswami, J., Morgan, C. J., Cheng, Y., Sheriff, H. M., Faselis, C., Mehta, R. L., Anker, S. D., Fonarow, G. C. & Ahmed, A. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38700246/
Neurological affection and serum neurofilament light chain in wild type transthyretin amyloidosis. Pernice, H. F., Knorz, A. L., Wetzel, P. J., Herrmann, C., Muratovic, H., Rieber, F., Asaad, E., Fiß, G., Barzen, G., Blüthner, E., Knebel, F., Spethmann, S., Messroghli, D., Heidecker, B., Brand, A., Wetz, C., Tschöpe, C. & Hahn, K. Sci Rep 14, 10111 (2024). https://pubmed.ncbi.nlm.nih.gov/38698025/
A Simple Bleeding Risk Score for the Complex Older Patient. Simonetti, F. & Kastrati, A. Am J Cardiol 223, 178-180 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38697452
Under pressure: Advances in device-based heart failure therapy for patients with preserved or mildly reduced ejection fraction. Stolz, L. & Hausleiter, J. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38700488/
Fostering healthy aging through selective nutrition: A long-term comparison of two dietary patterns and their holistic impact on mineral status in middle-aged individuals-A randomized controlled intervention trial in Germany. Pellowski, D., Heinze, T., Tuchtenhagen, M., Muller, S. M., Meyer, S., Maares, M., Gerbracht, C., Wernicke, C., Haase, H., Kipp, A. P., Grune, T., Pfeiffer, A. F. H., Mai, K. & Schwerdtle, T. J Trace Elem Med Biol 84, 127462 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38701651
Cardiac Computed Tomography Screening for Tricuspid Transcatheter Annuloplasty Implantation. Barbieri, F., Niehues, S. M., Feuchtner, G. M., Skurk, C., Landmesser, U., Polak-Krasna, K., Dreger, H., Kasner, M. & Reinthaler, M. Circ Cardiovasc Imaging, e016292 (2024). https://pubmed.ncbi.nlm.nih.gov/38708594/
Transcatheter aortic valve implantation in a patient with the left coronary artery originating directly above the annulus: images in cardiology. Lee, C. B., Hinkov, H., Dreger, H., Klein, C. & Unbehaun, A. Eur Heart J Case Rep 8, ytae212 (2024). https://pubmed.ncbi.nlm.nih.gov/38707524/
Testosterone and the risk of incident atrial fibrillation in older men: further analysis of the ASPREE study. Tran, C., Yeap, B. B., Ball, J., Clayton-Chubb, D., Hussain, S. M., Brodtmann, A., Tonkin, A. M., Neumann, J. T., Schneider, H. G., Fitzgerald, S., Woods, R. L. & McNeil, J. J. EClinicalMedicine 72, 102611 (2024). https://pubmed.ncbi.nlm.nih.gov/38707912/
Critical aortic stenosis - The long-term burden. Voges, I. & Hansen, J. H. Int J Cardiol 408, 132134 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38705208
Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression. Lozano-Vidal, N., Stanicek, L., Bink, D. I., Juni, R. P., Hooglugt, A., Kremer, V., Phelp, P., van Bergen, A., MacInnes, A. W., Dimmeler, S. & Boon, R. A. Commun Biol7, 541 (2024). https://pubmed.ncbi.nlm.nih.gov/38714838/
Angiotensin-(1-12): Does It Exist? A Critical Evaluation in Humans, Rats, and Mice. Rodrigues, A. F., Domenig, O., Poglitsch, M., Bader, M. & Danser, A. H. J. Hypertension81, 1776-1784 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38716648
Cardiac biomarkers for diagnosing Takotsubo syndrome. Schweiger, V., Di Vece, D., Cammann, V. L., Koleva, I., Wurdinger, M., Gilhofer, T., Rajman, K., Szawan, K. A., Niederseer, D., Citro, R., Vecchione, C., Bossone, E., Gili, S., Neuhaus, M., Franke, J., Meder, B., Jaguszewski, M., Noutsias, M., Knorr, M., Jansen, T., D'Ascenzo, F., Bruno, F., De Filippo, O., Stefanini, G., Campo, G., Wanha, W., Raposeiras Roubin, S., Dichtl, W., von Lewinski, D., Burgdorf, C., Kherad, B., Tschope, C., Sarcon, A., Shinbane, J., Rajan, L., Michels, G., Pfister, R., Cuneo, A., Jacobshagen, C., Karakas, M., Koenig, W., Pott, A., Meyer, P., Roffi, M., Banning, A., Wolfrum, M., Cuculi, F., Kobza, R., Fischer, T. A., Vasankari, T., Airaksinen, K. E. J., Napp, L. C., Dworakowski, R., MacCarthy, P., Kaiser, C., Osswald, S., Galiuto, L., Chan, C., Bridgman, P., Beug, D., Delmas, C., Lairez, O., Gilyarova, E., Shilova, A., Gilyarov, M., El-Battrawy, I., Akin, I., Polednikova, K., Tousek, P., Winchester, D. E., Massoomi, M., Galuszka, J., Ukena, C., Poglajen, G., Carrilho-Ferreira, P., Hauck, C., Paolini, C., Bilato, C., Kobayashi, Y., Kato, K., Ishibashi, I., Himi, T., Din, J., Al-Shammari, A., Prasad, A., Rihal, C. S., Liu, K., Schulze, P. C., Bianco, M., Jorg, L., Rickli, H., Pestana, G., Nguyen, T. H., Bohm, M., Maier, L. S., Pinto, F. J., Widimsky, P., Felix, S. B., Braun-Dullaeus, R. C., Rottbauer, W., Hasenfuss, G., Pieske, B. M., Schunkert, H., Budnik, M., Opolski, G., Thiele, H., Bauersachs, J., Horowitz, J. D., Di Mario, C., Kong, W., Dalakoti, M., Imori, Y., Munzel, T., Bax, J. J., Luscher, T. F., Crea, F., Ruschitzka, F., Ghadri, J. R. & Templin, C. Eur Heart J 45, 2254-2258 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38717630
Anticoagulation in COVID-19 patients - An updated systematic review and meta-analysis. Reis, S., Faske, A., Monsef, I., Langer, F., Müller, O. J., Kranke, P., Meybohm, P. & Weibel, S. Thromb Res 238, 141-150 (2024). https://pubmed.ncbi.nlm.nih.gov/38718472/
Influence of tricuspid regurgitation on the prognosis of patients with cardiogenic shock. Ruka, M., Schupp, T., Weidner, K., Egner-Walter, S., Forner, J., Mashayekhi, K., Tajti, P., Ayoub, M., Akin, M., Behnes, M., Akin, I. & Rusnak, J. Curr Med Res Opin, 1-16 (2024). https://pubmed.ncbi.nlm.nih.gov/38720658/
Repeated Injection of Very Small Superparamagnetic Iron Oxide Particles (VSOPs) in Murine Atherosclerosis: A Safety Study. Haase, T., Ludwig, A., Stach, A., Mohtashamdolatshahi, A., Hauptmann, R., Mundhenk, L., Kratz, H., Metzkow, S., Kader, A., Freise, C., Mueller, S., Stolzenburg, N., Radon, P., Liebl, M., Wiekhorst, F., Hamm, B., Taupitz, M. & Schnorr, J. Nanomaterials (Basel)14 (2024). https://pubmed.ncbi.nlm.nih.gov/38727367/
Pacemaker Channels and the Chronotropic Response in Health and Disease. Hennis, K., Piantoni, C., Biel, M., Fenske, S. & Wahl-Schott, C. Circ Res 134, 1348-1378 (2024). https://pubmed.ncbi.nlm.nih.gov/38723033/
Detectable troponin below the 99(th) percentile predicts survival in patients undergoing coronary angiography. Michel, L., Jehn, S., Dykun, I., Anker, M. S., Ferdinandy, P., Dobrev, D., Rassaf, T., Mahabadi, A. A. & Totzeck, M. Int J Cardiol Heart Vasc 52, 101419 (2024). https://pubmed.ncbi.nlm.nih.gov/38725439/
The Rise of T2. Nagel, E. & Pappas, L. JACC Cardiovasc Imaging (2024). https://pubmed.ncbi.nlm.nih.gov/38727645/
TPT-004, a Next-Generation Inhibitor of Tryptophan Hydroxylase, Ameliorates Pulmonary Arterial Hypertension in Rats. Wesolowski, R., Pleimes, D., Specker, E. & Bader, M. J Am Heart Assoc, e034240 (2024). https://pubmed.ncbi.nlm.nih.gov/38726898/
Poor Decision Making and Sociability Impairment Following Central Serotonin Reduction in Inducible TPH2-Knockdown Rats. Alonso, L., Peeva, P., Fernández-Del Valle Alquicira, T., Erdelyi, N., Gil Nolskog, Á., Bader, M., Winter, Y., Alenina, N. & Rivalan, M. Int J Mol Sci 25 (2024). https://pubmed.ncbi.nlm.nih.gov/38732220/
Antiplatelet Effects of Flavonoid Aglycones Are Mediated by Activation of Cyclic Nucleotide-Dependent Protein Kinases. Balykina, A., Naida, L., Kirkgöz, K., Nikolaev, V. O., Fock, E., Belyakov, M., Whaley, A., Whaley, A., Shpakova, V., Rukoyatkina, N. & Gambaryan, S. Int J Mol Sci 25 (2024). https://pubmed.ncbi.nlm.nih.gov/38732081/
Misleading Impact of Mitral Regurgitation on the Evaluation of Left Ventricular Contractile Function in Heart Failure With Preserved Ejection Fraction. Dandel, M. J Card Fail 30, 1065-1066 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38729559
The Ascyrus Medical Dissection Stent: A One-Fits-All Strategy for the Treatment of Acute Type A Aortic Dissection? Pitts, L., Moon, M. C., Luehr, M., Kofler, M., Montagner, M., Sündermann, S., Buz, S., Starck, C., Falk, V. & Kempfert, J. J Clin Med 13 (2024). https://pubmed.ncbi.nlm.nih.gov/38731123/
The complexities of modeling lifetime risk in the general population. Bahls, M. & Groß, S. Eur J Prev Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38736304/
Updated 2022 ACC/AHA Guideline Improves Concordance Between TTE and CT in Monitoring Marfan Snydrome and Related Disorders, but Relevant Measurement Differences Remain Frequent. Kolck, J., Trippel, T. D., Philipp, K., Gehle, P., Geisel, D. & Beetz, N. L. Glob Heart 23, 28 (2024). https://pubmed.ncbi.nlm.nih.gov/38737456/
Comparison of cardiac output estimates obtained from the Antares oscillometric pulse wave analysis algorithm and from Doppler transthoracic echocardiography. Stäuber, A., Hoppe, M. W., Lapp, H., Richter, S., Ohlow, M. A., Dörr, M., Piper, C., Eckert, S., Coll-Barroso, M. T., Stäuber, F., Abanador-Kamper, N. & Baulmann, J. PLoS One 19, e0302793 (2024). https://pubmed.ncbi.nlm.nih.gov/38739601/
What we claim to do and what we really do - a discrepancy in heart failure treatment. Assmus, B. & Sossalla, S. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38740572/
Incidence and pattern of urgent revascularization in acute coronary syndromes treated with ticagrelor or prasugrel. Aytekin, A., Scalamogna, M., Coughlan, J. J., Lahu, S., Ndrepepa, G., Menichelli, M., Mayer, K., Wohrle, J., Bernlochner, I., Witzenbichler, B., Hochholzer, W., Sibbing, D., Angiolillo, D. J., Hemetsberger, R., Tolg, R., Valina, C., Muller, A., Kufner, S., Liebetrau, C., Xhepa, E., Hapfelmeier, A., Sager, H. B., Joner, M., Richardt, G., Laugwitz, K. L., Neumann, F. J., Schunkert, H., Schupke, S., Kastrati, A. & Cassese, S. Clin Res Cardiol113, 1060-1069 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38740722
[Arrhythmias and amyloidosis]. Papathanasiou, M., Schlender, L. S., Johnson, V. L. & Wakili, R. Herzschrittmacherther Elektrophysiol (2024). https://pubmed.ncbi.nlm.nih.gov/38740607/
From rare events to systematic data collection: the RESCUED registry for sudden cardiac death in the young in Germany. Barkauskas, R., Jenewein, T., Scheiper-Welling, S., Wilmes, V., Niess, C., Petzel-Witt, S., Reitz, A., Gradhand, E., Falagkari, A., Papathanasiou, M., Wakili, R., Leistner, D. M., Vasseur, J., Göbel, J., Storf, H., Toennes, S. W., Kettner, M., Verhoff, M. A., Beckmann, B. M., Kauferstein, S. & Corvest, E. Clin Res Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38748206/
Oral microbiota of patients with phenylketonuria: A nation-based cross-sectional study. Bingol, M., Cardilli, A., Bingol, A. C., Lober, U., Bang, C., Franke, A., Bartzela, T., Beblo, S., Monch, E., Stolz, S., Schaefer, A. S., Forslund, S. K. & Richter, G. M. J Clin Periodontol 51, 1081-1092 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38745393
Sparse Group Penalties for bi-level variable selection. Buch, G., Schulz, A., Schmidtmann, I., Strauch, K. & Wild, P. S. Biom J 66, e2200334 (2024). https://pubmed.ncbi.nlm.nih.gov/38747086/
egr3 is a mechanosensitive transcription factor gene required for cardiac valve morphogenesis. da Silva, A. R., Gunawan, F., Boezio, G. L. M., Faure, E., Théron, A., Avierinos, J. F., Lim, S., Jha, S. G., Ramadass, R., Guenther, S., Looso, M., Zaffran, S., Juan, T. & Stainier, D. Y. R. Sci Adv 10, eadl0633 (2024). https://pubmed.ncbi.nlm.nih.gov/38748804/
Leaflet modification before transcatheter aortic valve implantation in patients at risk for coronary obstruction: the ShortCut study. Dvir, D., Tchétché, D., Leon, M. B., Généreux, P., Seguy, B., Makkar, R., Pibarot, P., Gada, H., Nazif, T., Hildick-Smith, D., Kempfert, J., Dumonteil, N., Unbehaun, A., Modine, T., Whisenant, B., Caussin, C., Conradi, L., Waggoner, T., Mishell, J. M., Chetcuti, S. J., Kar, S., Rinaldi, M. J., Szerlip, M., Ramana, R. K., Blackman, D. J., Ben-Dor, I., Kornowski, R., Waksman, R., Gerckens, U., Denti, P., Kukucka, M., Ternacle, J., Skaf, S., Kovac, J., Jilaihawi, H., Patel, V., Jubeh, R., Abdel-Wahab, M. & Kodali, S. Eur Heart J (2024). https://pubmed.ncbi.nlm.nih.gov/38747561/
Deactivation of LVAD Support for Myocardial Recovery - Surgical Perspectives. Nickel, I., Potapov, E., Sun, B., Zimpfer, D., Koliopoulou, A., Adachi, I., Anyanwu, A., Falk, V., Atluri, P., Faerber, G., Goldstein, D., Yarboro, L., Slaughter, M. S., Milano, C., Tsukashita, M., D'Alessandro, D., Silvestry, S., Kirov, H., Bommareddi, S., Lanmüller, P., Doenst, T. & Selzman, C. H. J Heart Lung Transplant (2024). https://pubmed.ncbi.nlm.nih.gov/38744354/
Ferritin Levels on Hospital Admission Predict Hypoxic-Ischemic Encephalopathy in Patients After Out-of-Hospital Cardiac Arrest: A Prospective Observational Single-Center Study. Nickelsen, S., Grosse Darrelmann, E., Seidlmayer, L., Fink, K., Britsch, S., Duerschmied, D., Scharf, R. E., Elsaesser, A. & Helbing, T. J Intensive Care Med, 8850666241252602 (2024). https://pubmed.ncbi.nlm.nih.gov/38748543/
[Xenotransplantation of solid organs]. Schmoeckel, M., Langin, M., Reichart, B., Abicht, J. M., Bender, M., Denner, J., Marckmann, G., Brenner, P., Wolf, E. & Hagl, C. Chirurgie (Heidelb)95, 603-609 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38748210
Right ventricular to pulmonary artery coupling in patients with different types of aortic stenosis undergoing TAVI. Steffen, J., Lux, M., Stocker, T. J., Kneidinger, N., Löw, K., Doldi, P. M., Haum, M., Fischer, J., Stolz, L., Theiss, H., Rizas, K., Braun, D., Orban, M., Peterß, S., Hausleiter, J., Massberg, S. & Deseive, S. Clin Res Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38748208/
Increased Expression of Inactive Rhomboid Protein 2 in Circulating Monocytes after Acute Myocardial Infarction. van Dijck, P., Hannemann, C., Dreger, H., Stangl, V., Stangl, K., Ludwig, A. & Hewing, B. J Cardiovasc Transl Res (2024). https://pubmed.ncbi.nlm.nih.gov/38743187/
Deep cardiac phenotyping by cardiovascular magnetic resonance reveals subclinical focal and diffuse myocardial injury in patients with psoriasis (PSOR-COR study). Gröschel, J., Grassow, L., Blaszczyk, E., Lommel, K., Kokolakis, G., Sabat, R. & Schulz-Menger, J. Clin Res Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38753001/
Streamlined Generation of CRISPR/Cas9-Mediated Single-Cell Knockout Clones in Murine Cell Lines. Hub, T., Cornean, A., Round, K., Fleming, T., Freichel, M. & Medert, R. ACS Pharmacol Transl Sci 7, 1291-1301 (2024). https://pubmed.ncbi.nlm.nih.gov/38751646/
Platelets: Orchestrators of immunity in host defense and beyond. Nicolai, L., Pekayvaz, K. & Massberg, S. Immunity 57, 957-972 (2024). https://pubmed.ncbi.nlm.nih.gov/38749398/
Pig models for translational Duchenne muscular dystrophy research. Stirm, M., Klymiuk, N., Nagashima, H., Kupatt, C. & Wolf, E. Trends Mol Med (2024). https://pubmed.ncbi.nlm.nih.gov/38749865/
Epicardial fat volume is associated with primary coronary slow-flow phenomenon in patients with severe aortic stenosis undergoing transcatheter valve implantation. Weferling, M., Rolf, A., Treiber, J., Fischer-Rasokat, U., Liebetrau, C., Hamm, C. W., Dey, D. & Kim, W. K. BMC Cardiovasc Disord 24, 253 (2024). https://pubmed.ncbi.nlm.nih.gov/38750455/
Inclisiran administration potently and durably lowers LDL-C over an extended-term follow-up: the ORION-8 trial. Wright, R. S., Raal, F. J., Koenig, W., Landmesser, U., Leiter, L. A., Vikarunnessa, S., Lesogor, A., Maheux, P., Talloczy, Z., Zang, X., Schwartz, G. G. & Ray, K. K. Cardiovasc Res (2024). https://pubmed.ncbi.nlm.nih.gov/38753448/
Age-related and species-specific methylation changes in the protein-coding marmoset sperm epigenome. Dittrich, M., Bernhardt, L., Penfold, C. A., Boroviak, T. E., Drummer, C., Behr, R., Müller, T. & Haaf, T. Aging Cell, e14200 (2024). https://pubmed.ncbi.nlm.nih.gov/38757354/
Inclisiran in individuals with diabetes or obesity: Post hoc pooled analyses of the ORION-9, ORION-10 and ORION-11 Phase 3 randomized trials. Leiter, L. A., Raal, F. J., Schwartz, G. G., Koenig, W., Ray, K. K., Landmesser, U., Han, J., Conde, L. G. & Wright, R. S. Diabetes Obes Metab 26, 3223-3237 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38757725
Photoinduced C-H arylation of 1,3-azoles via copper/photoredox dual catalysis. Trienes, S., Xu, J. & Ackermann, L. Chem Sci 15, 7293-7299 (2024). https://pubmed.ncbi.nlm.nih.gov/38756807/
Electrocardiographic Risk Stratification in Primary Prophylactic Implantable Cardioverter Defibrillator Patients: Can Future Arrhythmias Correlating with Sudden Cardiac Death Be Predicted? Zabel, M. & Friede, T. Europace (2024). https://pubmed.ncbi.nlm.nih.gov/38758091/
OCT-Guided versus Angiography-Guided Coronary Stent Implantation in Complex Lesions: An ILUMIEN IV Substudy. Ali, Z. A., Landmesser, U., Maehara, A., Shin, D., Sakai, K., Matsumura, M., Shlofmitz, R. A., Leistner, D., Canova, P., Alfonso, F., Fabbiocchi, F., Guagliumi, G., Price, M. J., Hill, J. M., Akasaka, T., Prati, F., Bezerra, H. G., Wijns, W., McGreevy, R. J., McNutt, R. W., Nie, H., Phalakornkule, K., Buccola, J. & Stone, G. W. J Am Coll Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38759907/
Full-Moon Coronary Calcification as Detected With Computed Tomography Angiography in Chronic Total Occlusion Percutaneous Coronary Intervention. Panuccio, G., Werner, G. S., De Rosa, S., Torella, D., Leistner, D. M., Siegrist, P. T., Haghikia, A., Skurk, C., Mashayekhi, K., Landmesser, U. & Abdelwahed, Y. S. Am J Cardiol 222, 149-156 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38761964
Procedural and clinical outcomes of patients undergoing a TAVI in TAVI procedure: Rationale and design of the multicentre, prospective, observational ReTAVI registry. Parma, R., Joner, M., Saia, F., Cuisset, T., Delgado, V., Rodes-Cabau, J., Modine, T., Van Belle, E., Fovino, L. N., Landes, U., Abdel-Wahab, M., Zamorano, J. L., Eden, M., Cademartiri, F., Skipirzepa, J. N., Kurucova, J., Greinert, D., Bramlage, P. & Tarantini, G. Eur J Clin Invest, e14241 (2024). https://pubmed.ncbi.nlm.nih.gov/38767226/
"Loss of landing zone"-Stabilizing endovascular treatment solutions in the aortic arch after thoracic endovascular aortic repair. Radner, C., Pichlmaier, M. A., Stana, J., Buech, J., Hagl, C., Tsilimparis, N. & Peterss, S. J Vasc Surg Cases Innov Tech 10, 101498 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38764463
Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats. Steinfeldt, J., Wild, B., Buergel, T., Pietzner, M., Upmeier Zu Belzen, J., Vauvelle, A., Hegselmann, S., Denaxas, S., Hemingway, H., Langenberg, C., Landmesser, U., Deanfield, J. & Eils, R. Nat Commun 15, 4257 (2024). https://pubmed.ncbi.nlm.nih.gov/38763986/
Commissural alignment and the ACURATE neo2 transcatheter aortic valve: Impact on valve performance. Travieso, A., Toggweiler, S., Montarello, N., Renker, M., Tirado-Conte, G., Loretz, L., Charitos, E. I., Kim, W. K. & De Backer, O. Catheter Cardiovasc Interv104, 115-124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38764320
Development of a long noncoding RNA-based machine learning model to predict COVID-19 in-hospital mortality. Devaux, Y., Zhang, L., Lumley, A. I., Karaduzovic-Hadziabdic, K., Mooser, V., Rousseau, S., Shoaib, M., Satagopam, V., Adilovic, M., Srivastava, P. K., Emanueli, C., Martelli, F., Greco, S., Badimon, L., Padro, T., Lustrek, M., Scholz, M., Rosolowski, M., Jordan, M., Brandenburger, T., Benczik, B., Agg, B., Ferdinandy, P., Vehreschild, J. J., Lorenz-Depiereux, B., Dörr, M., Witzke, O., Sanchez, G., Kul, S., Baker, A. H., Fagherazzi, G., Ollert, M., Wereski, R., Mills, N. L. & Firat, H. Nat Commun 15, 4259 (2024). https://pubmed.ncbi.nlm.nih.gov/38769334/
Nocturnal heat exposure and stroke risk. He, C., Breitner, S., Zhang, S., Huber, V., Naumann, M., Traidl-Hoffmann, C., Hammel, G., Peters, A., Ertl, M. & Schneider, A. Eur Heart J 45, 2158-2166 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38768958
Association of atrial mechanical dispersion with atrial fibrillation recurrence following catheter ablation: results of the ASTRA-AF pilot study. Knappe, D., Vogler, J., Weimann, J., Banas, V., Yildirim, S., Memenga, F., Senftinger, J., Keil, L., Ismaili, D., Nies, M., Rillig, A., Willems, S., Blankenberg, S., Kirchhof, P., Metzner, A. & Sinning, C. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38771346
Cortico-limbic restructuring and atherosclerosis: a stressful liaison. Mohanta, S. K., Santovito, D. & Weber, C. Eur Heart J 45, 1765-1767 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38770964
Effect of SGLT2 inhibitors on heart failure outcomes and cardiovascular death across the cardiometabolic disease spectrum: a systematic review and meta-analysis. Usman, M. S., Bhatt, D. L., Hameed, I., Anker, S. D., Cheng, A. Y. Y., Hernandez, A. F., Jones, W. S., Khan, M. S., Petrie, M. C., Udell, J. A., Friede, T. & Butler, J. Lancet Diabetes Endocrinol 12, 447-461 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38768620
Cardiomyocyte-specific RXFP1 overexpression protects against pressure overload-induced cardiac dysfunction independently of relaxin. Wingert, J., Meinhardt, E., Sasipong, N., Pott, M., Lederer, C., de la Torre, C., Sticht, C., Most, P., Katus, H. A., Frey, N., Raake, P. W. J. & Schlegel, P. Biochem Pharmacol 225, 116305 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38768763
Cardiovascular and genetic determinants of platelet high responsiveness: results from the Gutenberg Health Study. Baidildinova, G., Ten Cate, V., Panova-Noeva, M., Dahlen, B., Gieswinkel, A., von Ungern-Sternberg, S., Rapp, S., Strauch, K., Beutel, M. E., Pfeiffer, N., Lackner, K. J., Munzel, T., Ten Cate, H., Wild, P. S. & Jurk, K. Blood Adv 8, 3870-3874 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38776438
Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes. Bradfeld, J. P., Kember, R. L., Ulrich, A., Balkhiyarova, Z., Alyass, A., Aris, I. M., Bell, J. A., Broadaway, K. A., Chen, Z., Chai, J. F., Davies, N. M., Fernandez-Orth, D., Bustamante, M., Fore, R., Ganguli, A., Heiskala, A., Hottenga, J. J., Iniguez, C., Kobes, S., Leinonen, J., Lowry, E., Lyytikainen, L. P., Mahajan, A., Pitkanen, N., Schnurr, T. M., Have, C. T., Strachan, D. P., Thiering, E., Vogelezang, S., Wade, K. H., Wang, C. A., Wong, A., Holm, L. A., Chesi, A., Choong, C., Cruz, M., Elliott, P., Franks, S., Frithiof-Bojsoe, C., Gauderman, W. J., Glessner, J. T., Gilsanz, V., Griesman, K., Hanson, R. L., Kaakinen, M., Kalkwarf, H., Kelly, A., Kindler, J., Kahonen, M., Lanca, C., Lappe, J., Lee, N. R., McCormack, S., Mentch, F. D., Mitchell, J. A., Mononen, N., Niinikoski, H., Oken, E., Pahkala, K., Sim, X., Teo, Y. Y., Baier, L. J., van Beijsterveldt, T., Adair, L. S., Boomsma, D. I., de Geus, E., Guxens, M., Eriksson, J. G., Felix, J. F., Gilliland, F. D., Penn Medicine, B., Hansen, T., Hardy, R., Hivert, M. F., Holm, J. C., Jaddoe, V. W. V., Jarvelin, M. R., Lehtimaki, T., Mackey, D. A., Meyre, D., Mohlke, K. L., Mykkanen, J., Oberfeld, S., Pennell, C. E., Perry, J. R. B., Raitakari, O., Rivadeneira, F., Saw, S. M., Sebert, S., Shepherd, J. A., Standl, M., Sorensen, T. I. A., Timpson, N. J., Torrent, M., Willemsen, G., Hypponen, E., Power, C., Early Growth Genetics, C., McCarthy, M. I., Freathy, R. M., Widen, E., Hakonarson, H., Prokopenko, I., Voight, B. F., Zemel, B. S., Grant, S. F. A. & Cousminer, D. L. Genome Biol 25, 129 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38773652
Pulsed field ablation in patients with cardiac implantable electronic devices: an ex vivo assessment of safety. Lennerz, C., O'Connor, M., Schaarschmidt, C., Reents, T., Bourier, F., Telishevska, M., Lengauer, S., Popa, M., Wimbauer, K., Holmgren, E., Thoma, M., Spitzauer, L., Bahlke, F., Krafft, H., Englert, F., Knoll, K., Friedrich, L., Blazek, P., Hessling, G., Kolb, C., Deisenhofer, I. & Kottmaier, M. J Interv Card Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38775921
Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation. Pavlaki, N., Froese, A., Li, W., De Jong, K. A., Geertz, B., Subramanian, H., Mohagaonkar, S., Luo, X., Schubert, M., Wiegmann, R., Margaria, J. P., Ghigo, A., Kammerer, S., Hirsch, E., El-Armouche, A., Guan, K. & Nikolaev, V. O. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38776406
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Pekayvaz, K., Losert, C., Knottenberg, V., Gold, C., van Blokland, I. V., Oelen, R., Groot, H. E., Benjamins, J. W., Brambs, S., Kaiser, R., Gottschlich, A., Hoffmann, G. V., Eivers, L., Martinez-Navarro, A., Bruns, N., Stiller, S., Akgol, S., Yue, K., Polewka, V., Escaig, R., Joppich, M., Janjic, A., Popp, O., Kobold, S., Petzold, T., Zimmer, R., Enard, W., Saar, K., Mertins, P., Huebner, N., van der Harst, P., Franke, L. H., van der Wijst, M. G. P., Massberg, S., Heinig, M., Nicolai, L. & Stark, K. Nat Med 30, 1696-1710 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38773340
In vivo fluid dynamics of the Ventura interatrial shunt device in patients with heart failure. Pfeiffer, M., Boehmer, J., Gorcsan, J., Eguchi, S., Orihara, Y., Perl, M. L., Eigler, N., Abraham, W. T., Villota, J. N., Lee, E., Bayes-Genis, A., Moravsky, G., Kar, S., Zile, M. R., Holcomb, R., Anker, S. D., Stone, G. W., Rodes-Cabau, J., Lindenfeld, J. & Bax, J. J. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38773938
Heart's hidden battle: understanding Erdheim-Chester disease. Sato, R., Czepluch, F. & von Haehling, S. Heart 110, 885-886 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38772575
Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia. Weinberger, T., Denise, M., Joppich, M., Fischer, M., Garcia Rodriguez, C., Kumaraswami, K., Wimmler, V., Ablinger, S., Rauber, S., Fang, J., Liu, L., Liu, W. H., Winterhalter, J., Lichti, J., Thomas, L., Esfandyari, D., Percin, G., Matin, S., Hidalgo, A., Waskow, C., Engelhardt, S., Todica, A., Zimmer, R., Pridans, C., Gomez Perdiguero, E. & Schulz, C. Elife 12 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38775664
Mechanical circulatory support in patients with congenital heart disease: a European Registry for Patients with Mechanical Circulatory Support (EUROMACS) study. Ardissino, M., Morley, A. P., Lewis, C., Bhagra, C., Stoll, V., Popatov, E., Schoenrath, F., Gummert, J., Przybylowski, P., Sliwka, J., Meyns, B., de By, T., Jones, N. & Tsui, S. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38781499
Impact of empagliflozin on first and recurrent events leading to or prolonging hospitalisation in the EMPA-REG OUTCOME trial. Inzucchi, S. E., Wanner, C., Fitchett, D., Zinman, B., Anker, S. D., Pocock, S. J., Mattheus, M., Hantel, S. & Lund, S. S. Diabetes Res Clin Pract 212, 111715 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38777127
Lack of Formyl-peptide Receptor 1 Mitigates Atherosclerosis in Hyperlipidemic Mice. Doring, Y., Bender, A. & Soehnlein, O. Thromb Haemost (2024). https://www.ncbi.nlm.nih.gov/pubmed/38782024
Differences in presentation, diagnosis and management of heart failure in women. A scientific statement of the Heart Failure Association of the ESC. Rosano, G. M. C., Stolfo, D., Anderson, L., Abdelhamid, M., Adamo, M., Bauersachs, J., Bayes-Genis, A., Bohm, M., Chioncel, O., Filippatos, G., Hill, L., Lainscak, M., Lambrinou, E., Maas, A., Massouh, A. R., Moura, B., Petrie, M. C., Rakisheva, A., Ray, R., Savarese, G., Skouri, H., Van Linthout, S., Vitale, C., Volterrani, M., Metra, M. & Coats, A. J. S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783694
Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling. Schoger, E., Bleckwedel, F., Germena, G., Rocha, C., Tucholla, P., Sobitov, I., Mobius, W., Sitte, M., Lenz, C., Samak, M., Hinkel, R., Varga, Z. V., Giricz, Z., Salinas, G., Gross, J. C. & Zelarayan, L. C. Commun Biol 7, 624 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783104
Ca(V)1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy. Schwenzer, N., Teiwes, N. K., Kohl, T., Pohl, C., Giller, M. J., Lehnart, S. E. & Steinem, C. Commun Biol 7, 620 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783117
Human induced pluripotent stem cell-derived atrial cardiomyocytes recapitulate contribution of the slowly activating delayed rectifier currents IKs to repolarization in the human atrium. Sonmez, M. I., Goldack, S., Nurkkala, E., Schulz, C., Klampe, B., Schulze, T., Hansen, A., Eschenhagen, T., Koivumaki, J. & Christ, T. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38788213
Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series. Yule, M. S., Thompson, J., Leesahatsawat, K., Sousa, M. S., Anker, S. D., Arends, J., Balstad, T. R., Brown, L. R., Bye, A., Dajani, O., Fallon, M., Hjermstad, M. J., Jakobsen, G., McDonald, J., McGovern, J., Roeland, E. J., Sayers, J., Skipworth, R. J. E., Ottestad, I. O., Philips, I., Simpson, M. R., Solheim, T. S., Vagnildhaug, O. M., McMillan, D., Laird, B. J. A., Dolan, R. D. & Cancer Cachexia Endpoints Working, G. J Cachexia Sarcopenia Muscle15, 853-867 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38783477
Left Atrial Appendage Occlusion in Patients With Anticoagulation Failure vs Anticoagulation Contraindication. Aarnink, E. W., Maarse, M., Fierro, N., Mazzone, P., Beneduce, A., Tondo, C., Gasperetti, A., Pracon, R., Demkow, M., Zielinski, K., de Backer, O., Korsholm, K., Nielsen-Kudsk, J. E., Estevez-Loureiro, R., Caneiro-Queija, B., Benito-Gonzalez, T., Perez de Prado, A., Nombela-Franco, L., Salinas, P., Holmes, D., Almakadma, A. H., Berti, S., Romeo, M. R., Millan, X., Arzamendi, D., Alla, V. M., Agarwal, H., Eitel, I., Paitazoglou, C., Freixa, X., Cepas-Guillen, P., Chothia, R., Badejoko, S. O., Spoon, D. B., Maddux, J. T., El-Chami, M., Ram, P., Branca, L., Adamo, M., Suradi, H. S., Peper, J., van Dijk, V. F., Rensing, B., Swaans, M. J., Vireca, E., Bergmann, M. W., Boersma, L. V. A., Str-Oac, L. & Investigators, E. JACC Cardiovasc Interv 17, 1311-1321 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38795093
Comparison of interventional treatment options for coronary calcified nodules: A sub-analysis of the ROTA.shock trial. Blachutzik, F., Meier, S., Blachutzik, M., Schlattner, S., Gori, T., Ullrich-Daub, H., Gaede, L., Achenbach, S., Mollmann, H., Chitic, B., Aksoy, A., Nickenig, G., Weferling, M., Dorr, O., Boeder, N., Bayer, M., Hamm, C., Nef, H. & Investigators, R. O. s. Cardiovasc Revasc Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38796321
Stroke outcomes following durable left ventricular assist device implant in patients bridged with micro-axial flow pump: Insights from a large registry. Gallone, G., Lewin, D., Rojas Hernandez, S., Bernhardt, A., Billion, M., Meyer, A., Netuka, I., Kooij, J. J., Pieri, M., Szymanski, M. K., Moeller, C. H., Akhyari, P., Jawad, K., Krasivskyi, I., Schmack, B., Farber, G., Medina, M., Haneya, A., Zimpfer, D., Nersesian, G., Lanmueller, P., Spitaleri, A., Oezkur, M., Djordjevic, I., Saeed, D., Boffini, M., Stein, J., Gustafsson, F., Scandroglio, A. M., De Ferrari, G. M., Meyns, B., Hofmann, S., Belohlavek, J., Gummert, J., Rinaldi, M., Potapov, E. V. & Loforte, A. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/38803239
Safety and efficacy of the latest generation biodegradable polymer-coated ultrathin sirolimus-eluting stent in the treatment of coronary artery disease in a European all-comer population with or without high bleeding risk: The Cruz HBR Registry. Leistner, D. M., Rampat, R., Haude, M., Schmitz, T., Allali, A., Mollmann, H., Stahli, B. E., Rudolph, T. K., Lauten, A., Koning, R., Bogaerts, K., Sudhir, K. & Naber, C. Minerva Cardiol Angiol 72, 355-365 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38804621
New insights into the hypothalamic-pituitary-thyroid axis: a transcriptome- and proteome-wide association study. Monteiro-Martins, S., Sterenborg, R., Borisov, O., Scherer, N., Cheng, Y., Medici, M., Kottgen, A. & Teumer, A. Eur Thyroid J 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38805593
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Pelli, A., Kentta, T. V., Junttila, M. J., Huber, C., Schlogl, S., Zabel, M., Malik, M., Willems, R., Vos, M. A., Harden, M., Friede, T., Sticherling, C., Huikuri, H. V. & Investigators, E.-C.-I. S. J Am Heart Assoc 13, e032465 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38804218
2024 update in heart failure. Beghini, A., Sammartino, A. M., Papp, Z., von Haehling, S., Biegus, J., Ponikowski, P., Adamo, M., Falco, L., Lombardi, C. M., Pagnesi, M., Savarese, G., Metra, M. & Tomasoni, D. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38806171
Impact of malnutrition in patients with severe heart failure. Pagnesi, M., Serafini, L., Chiarito, M., Stolfo, D., Baldetti, L., Inciardi, R. M., Tomasoni, D., Adamo, M., Lombardi, C. M., Sammartino, A. M., Loiacono, F., Maccallini, M., Villaschi, A., Gasparini, G., Montella, M., Contessi, S., Cocianni, D., Perotto, M., Barone, G., Anker, S. D., Merlo, M., Cappelletti, A. M., Sinagra, G., Pini, D. & Metra, M. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38808603
Spontaneous coronary artery dissection - We are the patients. Senftinger, J., Poss, J. & Clemmensen, P. Eur Heart J Acute Cardiovasc Care (2024). https://www.ncbi.nlm.nih.gov/pubmed/38809768
Spontaneous coronary artery dissection: we are the patients. Senftinger, J., Poss, J. & Clemmensen, P. Eur Heart J Acute Cardiovasc Care 13, 521-522 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38809768
Atherosclerosis is an inflammatory disease: treat it as such! Therre, M., Wenzel, P. & Haring, B. Clin Res Cardiol 113, 1274-1275 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38806822
Identification of a functional missense variant in the matrix metallopeptidase 10 (MMP10) gene in two families with premature myocardial infarction. Verovenko, V., Tennstedt, S., Kleinecke, M., Kessler, T., Schunkert, H., Erdmann, J., Ensminger, S. & Aherrahrou, Z. Sci Rep 14, 12212 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38806571
Plasma proteome association with coronary heart disease and carotid intima media thickness: results from the KORA F4 study. Elhadad, M. A., Del, C. G.-A. M., Chen, C. W., Neumeyer, S., Delerue, T., Rathmann, W., Nabauer, M., Meisinger, C., Kaab, S., Seissler, J., Graumann, J., Koenig, W., Suhre, K., Gieger, C., Volker, U., Peters, A., Hammer, E. & Waldenberger, M. Cardiovasc Diabetol 23, 181 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38811951
Mediastinal transposition of the greater omentum for treatment of infected prostheses of the ascending aorta and aortic arch. Pitts, L., Pasic, M., Wert, L., Nersesian, G., Kaemmel, J., Buz, S., Knosalla, C., Dusterhoft, V., Starck, C., Kempfert, J., Jacobs, S. & Falk, V. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38814808
Residual tricuspid regurgitation after tricuspid transcatheter edge-to-edge repair: Insights into the EuroTR registry. Stolz, L., Kresoja, K. P., von Stein, J., Fortmeier, V., Koell, B., Rottbauer, W., Kassar, M., Goebel, B., Denti, P., Achouh, P., Rassaf, T., Barreiro-Perez, M., Boekstegers, P., Ruck, A., Doldi, P. M., Novotny, J., Zdanyte, M., Adamo, M., Vincent, F., Schlegel, P., von Bardeleben, R. S., Stocker, T. J., Weckbach, L. T., Wild, M. G., Brunner, S., Toggweiler, S., Grapsa, J., Patterson, T., Thiele, H., Kister, T., Konstandin, M. H., Van Belle, E., Metra, M., Geisler, T., Estevez-Loureiro, R., Luedike, P., Karam, N., Maisano, F., Lauten, P., Praz, F., Kessler, M., Kalbacher, D., Rudolph, V., Iliadis, C., Lurz, P., Hausleiter, J. & on behalf of the Euro, T. R. I. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38812292
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications. Bode, D., Pronto, J. R. D., Schiattarella, G. G. & Voigt, N. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38816507
Sex-specific ventricular morphology, function, and tissue characteristics in arterial hypertension: a magnetic resonance study of the Hamburg city health cohort. Erley, J., Jahnke, C. M., Schuttler, S., Molwitz, I., Chen, H., Meyer, M., Muellerleile, K., Cavus, E., Lund, G. K., Blankenberg, S., Adam, G. & Tahir, E. Eur Radiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38819515
Pulmonary 4D-flow MRI imaging in landrace pigs under rest and stress. Faragli, A., Hullebrand, M., Berendsen, A. J., Sola, L. T., Lo Muzio, F. P., Gotze, C., Tanacli, R., Doeblin, P., Stehning, C., Schnackenburg, B., Van der Vosse, F. N., Nagel, E., Post, H., Hennemuth, A., Alogna, A. & Kelle, S. Int J Cardiovasc Imaging 40, 1511-1524 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38819601
Microvascular dysfunction in heart transplantation is associated with altered cardiomyocyte mitochondrial structure and unimpaired excitation-contraction coupling. Hohendanner, F., Boegner, M., Huettemeister, J., Zhang, K., Dreysse, S., Knosalla, C., Falk, V., Schoenrath, F., Just, I. A. & Stawowy, P. PLoS One 19, e0303540 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38820336
Transcatheter heart valve explant with infective endocarditis-associated prosthesis failure and outcomes: the EXPLANT-TAVR international registry. Marin-Cuartas, M., Tang, G. H. L., Kiefer, P., Fukuhara, S., Lange, R., Harrington, K. B., Saha, S., Hagl, C., Kleiman, N. S., Goel, S. S., Kempfert, J., Werner, P., Petrossian, G. A., Geirsson, A., Desai, N. D., Chu, M. W. A., Bhadra, O. D., Shults, C., Garatti, A., Vincent, F., Grubb, K. J., Goldberg, J. B., Mack, M. J., Modine, T., Denti, P., Kaneko, T., Bapat, V. N., Reardon, M. J., Borger, M. A., Zaid, S. & Investigators, E.-T. Eur Heart J 45, 2519-2532 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38820201
Mitochondrial DNA variants and microbiota: An experimental strategy to identify novel therapeutic potential in chronic inflammatory diseases. Olbrich, M., Hartmann, A. M., Kunzel, S., Aherrahrou, Z., Schilf, P., Baines, J. F., Ibrahim, S. M. & Hirose, M. Pharmacol Res 205, 107231 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38815878
S100A1's single cysteine is an indispensable redox-switch for the protection against diastolic calcium wavesin cardiomyocytes. Seitz, A., Busch, M., Kroemer, J., Schneider, A., Simon, S., Jungmann, A., Katus, H. A., Most, P. & Ritterhoff, J. Am J Physiol Heart Circ Physiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38819384
April
Paper of the Month
Transcatheter or Surgical Treatment of Aortic-Valve Stenosis
DZHK-Autor:innen: Stefan Blankenberg, Peter Clemmensen, Jochen Cremer, Nina Diercks, Ingo Eitel, Stephan Ensminger, Derk Frank, Inke R. König, Hermann Reichenspurner, Raphael Twerenbold, Christian Hagl, Markus Krane, Norbert Frey, Matthias Karck, Christian Hamm, Won-Keun Kim, Thomas Walther, Ulf Landmesser, Volkmar Falk. The New England Journal of Medicine.
Body mass index and cardiorenal outcomes in the EMPEROR-Preserved trial: Principal findings and meta-analysis with the DELIVER trial. Sattar, N., Butler, J., Lee, M. M. Y., Harrington, J., Sharma, A., Zannad, F., Filippatos, G., Verma, S., Januzzi, J. L., Ferreira, J. P., Pocock, S. J., Pfarr, E., Ofstad, A. P., Brueckmann, M., Packer, M. & Anker, S. D. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38558521
Impact of empagliflozin on insulin needs in patients with heart failure and diabetes: An EMPEROR-Pooled analysis. Talha, K. M., Green, J., Filippatos, G., Pocock, S., Zannad, F., Brueckmann, M., Schueler, E., Ofstad, A. P., Ferreira, J. P., Anker, S. D., Butler, J., Rosenstock, J. & Packer, M. Diabetes Obes Metab 26, 2578-2587 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38558314
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage. Tsvilovskyy, V., Ottenheijm, R., Kriebs, U., Schutz, A., Diakopoulos, K. N., Jha, A., Bildl, W., Wirth, A., Bock, J., Jaslan, D., Ferro, I., Taberner, F. J., Kalinina, O., Hildebrand, S., Wissenbach, U., Weissgerber, P., Vogt, D., Eberhagen, C., Mannebach, S., Berlin, M., Kuryshev, V., Schumacher, D., Philippaert, K., Camacho-Londono, J. E., Mathar, I., Dieterich, C., Klugbauer, N., Biel, M., Wahl-Schott, C., Lipp, P., Flockerzi, V., Zischka, H., Algul, H., Lechner, S. G., Lesina, M., Grimm, C., Fakler, B., Schulte, U., Muallem, S. & Freichel, M. J Clin Invest 134 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38557489
DLC1 promotes mechanotransductive feedback for YAP via RhoGAP-mediated focal adhesion turnover. Hooglugt, A., van der Stoel, M. M., Shapeti, A., Neep, B. F., de Haan, A., van Oosterwyck, H., Boon, R. A. & Huveneers, S. J Cell Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/38563084
Effect of liraglutide on thigh muscle fat and muscle composition in adults with overweight or obesity: Results from a randomized clinical trial. Pandey, A., Patel, K. V., Segar, M. W., Ayers, C., Linge, J., Leinhard, O. D., Anker, S. D., Butler, J., Verma, S., Joshi, P. H. & Neeland, I. J. J Cachexia Sarcopenia Muscle (2024). https://www.ncbi.nlm.nih.gov/pubmed/38561962
Interatrial shunt therapy in advanced heart failure: Outcomes from the open-label cohort of the RELIEVE-HF trial. Rodes-Cabau, J., Lindenfeld, J., Abraham, W. T., Zile, M. R., Kar, S., Bayes-Genis, A., Eigler, N., Holcomb, R., Nunez, J., Lee, E., Perl, M. L., Moravsky, G., Pfeiffer, M., Boehmer, J., Gorcsan, J., Bax, J. J., Anker, S. & Stone, G. W. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38561314
Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis. Tamiato, A., Tombor, L. S., Fischer, A., Muhly-Reinholz, M., Vanicek, L. R., Togru, B. N., Neitz, J., Glaser, S. F., Merten, M., Rodriguez Morales, D., Kwon, J., Klatt, S., Schumacher, B., Gunther, S., Abplanalp, W. T., John, D., Fleming, I., Wettschureck, N., Dimmeler, S. & Luxan, G. Circ Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38563133
Dapagliflozin and atrial fibrillation: elevated dosing to achieve class I antiarrhythmic effects? Christ, T., Schwedhelm, E. & Eschenhagen, T. Basic Res Cardiol (2024). www.ncbi.nlm.nih.gov/pubmed/38568224
Atrioventricular valve surgery in patients with univentricular heart and two separate atrioventricular valves. Mayr, B., Osawa, T., Staehler, H., Schaeffer, T., Rohlig, C., Cleuziou, J., Hager, A., Ewert, P., Horer, J., Lange, R. & Ono, M. Cardiol Young, 1-9 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38567959
Drivers and recent trends of hospitalisation costs related to acute pulmonary embolism. Mohr, K., Hobohm, L., Kaier, K., Farmakis, I. T., Valerio, L., Barco, S., Abele, C., Munzel, T., Neusius, T., Konstantinides, S., Binder, H. & Keller, K. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38565711
Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma. Yalcin, F., Haneke, H., Efe, I. E., Kuhrt, L. D., Motta, E., Nickl, B., Fluh, C., Synowitz, M., Dzaye, O., Bader, M. & Kettenmann, H. Acta Neuropathol Commun 12, 50 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38566120
mtDNA analysis using Mitopore. Dobner, J., Nguyen, T., Pavez-Giani, M. G., Cyganek, L., Distelmaier, F., Krutmann, J., Prigione, A. & Rossi, A. Mol Ther Methods Clin Dev 32, 101231 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38572068
Noise annoyance due to different sources is associated with tinnitus presence and distress in the general population. Hahad, O., Doge, J., Bahr-Hamm, K., Beutel, M. E., Kontohow-Beckers, K., Schuster, A. K., Keller, K., Hobohm, L., Schmitt, V. H., Gianicolo, E., Lackner, K. J., Daiber, A., Wild, P. S., Hackenberg, B. & Munzel, T. J Expo Sci Environ Epidemiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38570612
Mapping the interplay of immunoproteasome and autophagy in different heart failure phenotypes. Ott, C. Free Radic Biol Med 218, 149-165 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38570171
Congestion patterns in severe tricuspid regurgitation and transcatheter treatment: Insights from a multicentre registry. Rommel, K. P., Bonnet, G., Fortmeier, V., Stolz, L., Schober, A. R., von Stein, J., Kassar, M., Gercek, M., Rosch, S., Stocker, T. J., Korber, M. I., Kresoja, K. P., Rudolph, T. K., Pfister, R., Baldus, S., Windecker, S., Thiele, H., Praz, F., Hausleiter, J., Rudolph, V., Burkhoff, D. & Lurz, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38571456
Unravelling the molecular interplay: SUMOylation, PML nuclear bodies and vascular cell activity in health and disease. Berkholz, J. & Karle, W. Cell Signal 119, 111156 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38574938
Large-scale assessment of physical activity in a population using high-resolution hip-worn accelerometry: the German National Cohort (NAKO). Weber, A., van Hees, V. T., Stein, M. J., Gastell, S., Steindorf, K., Herbolsheimer, F., Ostrzinski, S., Pischon, T., Brandes, M., Krist, L., Marschollek, M., Greiser, K. H., Nimptsch, K., Brandes, B., Jochem, C., Sedlmeier, A. M., Berger, K., Brenner, H., Buck, C., Castell, S., Dorr, M., Emmel, C., Fischer, B., Flexeder, C., Harth, V., Hebestreit, A., Heise, J. K., Holleczek, B., Keil, T., Koch-Gallenkamp, L., Lieb, W., Meinke-Franze, C., Michels, K. B., Mikolajczyk, R., Kluttig, A., Obi, N., Peters, A., Schmidt, B., Schipf, S., Schulze, M. B., Teismann, H., Waniek, S., Willich, S. N., Leitzmann, M. F. & Baurecht, H. Sci Rep 14, 7927 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38575636
Mst4, a novel cardiac STRIPAK complex associated kinase, regulates cardiomyocyte growth and survival and is upregulated in human cardiomyopathy. Eden, M., Leye, M., Hahn, J., Heilein, E., Luzarowski, M., Volschow, B., Tannert, C., Sossalla, S., Lucena-Porcel, C., Frank, D. & Frey, N. J Biol Chem, 107255 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38579991
Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights from the EMPACT-MI Trial. Hernandez, A. F., Udell, J. A., Jones, W. S., Anker, S. D., Petrie, M. C., Harrington, J., Mattheus, M., Seide, S., Zwiener, I., Amir, O., Bahit, M. C., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V. K., Figtree, G., Ge, J., Goodman, S., Gotcheva, N., Goto, S., Gasior, T., Jamal, W., Januzzi, J. L., Jeong, M. H., Lopatin, Y., Lopes, R. D., Merkely, B., Parikh, P. B., Parkhomenko, A., Ponikowski, P., Rossello, X., Schou, M., Simic, D., Steg, P. G., Szachniewicz, J., van der Meer, P., Vinereanu, D., Zieroth, S., Brueckmann, M., Sumin, M., Bhatt, D. L. & Butler, J. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38581389
Pediatric Z-Score Calculator of Cardiac MRI Volumetric Measurements. Voges, I., Caliebe, A., Hinz, S., Daubeney, P., Boroni Gracioli, S., Mohiaddin, R. H., Uebing, A. S., Pennell, D. J., Gabbert, D. D. & Krupickova, S. J Magn Reson Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38580327
RNA-DNA triplexes: molecular mechanisms and functional relevance. Leisegang, M. S., Warwick, T., Stotzel, J. & Brandes, R. P. Trends Biochem Sci (2024). https://www.ncbi.nlm.nih.gov/pubmed/38582689
Sodium Glucose Co-transporter 2 Inhibitors and Major Adverse Cardiovascular Outcomes: A SMART-C Collaborative Meta-Analysis. Patel, S. M., Kang, Y. M., Im, K., Neuen, B. L., Anker, S. D., Bhatt, D. L., Butler, J., Cherney, D. Z. I., Claggett, B. L., Fletcher, R. A., Herrington, W. G., Inzucchi, S. E., Jardine, M. J., Mahaffey, K. W., McGuire, D. K., McMurray, J. J. V., Neal, B., Packer, M., Perkovic, V., Solomon, S. D., Staplin, N., Vaduganathan, M., Wanner, C., Wheeler, D. C., Zannad, F., Zhao, Y., Heerspink, H. J. L., Sabatine, M. S. & Wiviott, S. D. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38583093
Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON). Appel, K. S., Nurnberger, C., Bahmer, T., Forster, C., Polidori, M. C., Kohls, M., Kraus, T., Hettich-Damm, N., Petersen, J., Blaschke, S., Brohl, I., Butzmann, J., Dashti, H., Deckert, J., Dreher, M., Fiedler, K., Finke, C., Geisler, R., Hanses, F., Hopff, S. M., Jensen, B. O., Konik, M., Lehnert, K., de Miranda, S. M. N., Mitrov, L., Miljukov, O., Reese, J. P., Rohde, G., Scherer, M., Tausche, K., Tebbe, J. J., Vehreschild, J. J., Voit, F., Wagner, P., Weigl, M., Lemhofer, C. & Group, N. S. Infection (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587752
Transcatheter or Surgical Treatment of Aortic-Valve Stenosis. Blankenberg, S., Seiffert, M., Vonthein, R., Baumgartner, H., Bleiziffer, S., Borger, M. A., Choi, Y. H., Clemmensen, P., Cremer, J., Czerny, M., Diercks, N., Eitel, I., Ensminger, S., Frank, D., Frey, N., Hagendorff, A., Hagl, C., Hamm, C., Kappert, U., Karck, M., Kim, W. K., Konig, I. R., Krane, M., Landmesser, U., Linke, A., Maier, L. S., Massberg, S., Neumann, F. J., Reichenspurner, H., Rudolph, T. K., Schmid, C., Thiele, H., Twerenbold, R., Walther, T., Westermann, D., Xhepa, E., Ziegler, A., Falk, V. & Investigators, D.-D. T. N Engl J Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38588025
Insulin-like growth factor binding protein-7 concentrations in chronic heart failure: Results from the EMPEROR programme. Ferreira, J. P., Packer, M., Sattar, N., Butler, J., Gonzalez Maldonado, S., Panova-Noeva, M., Sumin, M., Masson, S., Pocock, S. J., Anker, S. D., Zannad, F. & Januzzi, J. L. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587259
Association of an impaired GH-IGF-I axis with cardiac wasting in patients with advanced cancer. Frohlich, A. K., Porthun, J., Talha, K. M., Lena, A., Hadzibegovic, S., Wilkenshoff, U., Sonntag, F., Nikolski, A., Ramer, L. V., Zeller, T., Keller, U., Bullinger, L., Anker, S. D., Haverkamp, W., von Haehling, S., Doehner, W., Rauch, U., Skurk, C., Cleland, J. G. F., Butler, J., Coats, A. J. S., Landmesser, U., Karakas, M. & Anker, M. S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587563
The role of coronary artery disease in lung transplantation: a propensity-matched analysis. Lusebrink, E., Gade, N., Seifert, P., Ceelen, F., Veit, T., Fohrer, F., Hoffmann, S., Hopler, J., Binzenhofer, L., Roden, D., Saleh, I., Lanz, H., Michel, S., Schneider, C., Irlbeck, M., Tomasi, R., Hatz, R., Hausleiter, J., Hagl, C., Magnussen, C., Meder, B., Zimmer, S., Luedike, P., Schafer, A., Orban, M., Milger, K., Behr, J., Massberg, S. & Kneidinger, N. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38587564
Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation. Maurer, W., Rebs, S., Kohne, S., Eberl, H., Wollnik, B., Zibat, A. & Streckfuss-Bomeke, K. Stem Cell Res 77, 103409 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38583294
Lack of Laminar Shear Stress Facilitates the Endothelial Uptake of Very Small Superparamagnetic Iron Oxide Nanoparticles by Modulating the Endothelial Surface Layer. Twamley, S. G., Gimber, N., Sanchez-Ibarra, H. E., Christaller, T., Isakzai, V., Kratz, H., Mitra, R., Kampen, L., Stach, A., Heilmann, H., Sohl-Kielczynski, B., Ebong, E. E., Schmoranzer, J., Munster-Wandowski, A. & Ludwig, A. Int J Nanomedicine 19, 3123-3142 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38585474
Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation. Zhu, Y., Ackers-Johnson, M., Shanmugam, M. K., Pakkiri, L. S., Drum, C. L., Chen, Y., Kim, J., Paltzer, W. G., Mahmoud, A. I., Wen Tan, W. L., Lee, M. C. J., Jiang, J., Luu, D. A. T., Ng, S. L., Li, P. Y. Q., Wang, A., Qi, R., Ong, G. J. X., Ng Yu, T., Haigh, J. J., Tiang, Z., Richards, A. M. & Foo, R. Circulation (2024). https://www.ncbi.nlm.nih.gov/pubmed/38586957
Spatial characteristics of non-communicable diseases and their associations to social conditions in a large urban cohort in Germany-Results from the Hamburg City Health Study. Andrees, V., Bei der Kellen, R., Augustin, M., Gallinat, J., Harth, V., Hoven, H., Kuhn, S., Lautenbach, A., Magnussen, C., Mohr, N., Twerenbold, R., Schafer, I., Waschki, B., Zyriax, B. C. & Augustin, J. PLoS One 19, e0301475 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38593150
Infection, inflammation, and cardiovascular risk: are we underestimating an old disease? Arnold, N. & Koenig, W. Eur Heart J (2024). www.ncbi.nlm.nih.gov/pubmed/38591639
An International Multicenter Cohort Study on Implantable Cardioverter Defibrillators for the Treatment of Symptomatic Children with Catecholaminergic Polymorphic Ventricular Tachycardia. Lamba, A., Roston, T. M., Peltenburg, P. J., Kallas, D., Franciosi, S., Lieve, K. V. V., Kannankeril, P. J., Horie, M., Ohno, S., Brugada, R., Aiba, T., Fischbach, P., Knight, L., Till, J., Kwok, S. Y., Probst, V., Backhoff, D., LaPage, M. J., Batra, A. S., Drago, F., Haugaa, K., Krahn, A. D., Robyns, T., Swan, H., Tavacova, T., Atallah, J., Borggrefe, M., Rudic, B., Sarquella-Brugada, G., Chorin, E., Hill, A., Kammeraad, J., Kamp, A., Law, I., Perry, J., Roberts, J. D., Tisma-Dupanovic, S., Semsarian, C., Skinner, J. R., Tfelt-Hansen, J., Denjoy, I., Leenhardt, A., Schwartz, P. J., Ackerman, M. J., Wilde, A. A. M., van der Werf, C. & Sanatani, S. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/38588993
Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference. Linz, D., Andrade, J. G., Arbelo, E., Boriani, G., Breithardt, G., Camm, A. J., Caso, V., Nielsen, J. C., De Melis, M., De Potter, T., Dichtl, W., Diederichsen, S. Z., Dobrev, D., Doll, N., Duncker, D., Dworatzek, E., Eckardt, L., Eisert, C., Fabritz, L., Farkowski, M., Filgueiras-Rama, D., Goette, A., Guasch, E., Hack, G., Hatem, S., Haeusler, K. G., Healey, J. S., Heidbuechel, H., Hijazi, Z., Hofmeister, L. H., Hove-Madsen, L., Huebner, T., Kaab, S., Kotecha, D., Malaczynska-Rajpold, K., Merino, J. L., Metzner, A., Mont, L., Ng, G. A., Oeff, M., Parwani, A. S., Puererfellner, H., Ravens, U., Rienstra, M., Sanders, P., Scherr, D., Schnabel, R., Schotten, U., Sohns, C., Steinbeck, G., Steven, D., Toennis, T., Tzeis, S., van Gelder, I. C., van Leerdam, R. H., Vernooy, K., Wadhwa, M., Wakili, R., Willems, S., Witt, H., Zeemering, S. & Kirchhof, P. Europace 26 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38591838
Oral anticoagulation in device-detected atrial fibrillation: effects of age, sex, cardiovascular comorbidities, and kidney function on outcomes in the NOAH-AFNET 6 trial. Lip, G. Y. H., Nikorowitsch, J., Sehner, S., Becher, N., Bertaglia, E., Blomstrom-Lundqvist, C., Brandes, A., Beuger, V., Calvert, M., Camm, A. J., Chlouverakis, G., Dan, G. A., Dichtl, W., Diener, H. C., Fierenz, A., Goette, A., de Groot, J. R., Hermans, A., Lubinski, A., Marijon, E., Merkely, B., Mont, L., Ozga, A. K., Rajappan, K., Sarkozy, A., Scherr, D., Schnabel, R. B., Schotten, U., Simantirakis, E., Toennis, T., Vardas, P., Wichterle, D., Zapf, A. & Kirchhof, P. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38591192
Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction. Udell, J. A., Petrie, M. C., Jones, W. S., Anker, S. D., Harrington, J., Mattheus, M., Seide, S., Amir, O., Bahit, M. C., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V. K., Figtree, G., Ge, J., Goodman, S. G., Gotcheva, N., Goto, S., Gasior, T., Jamal, W., Januzzi, J. L., Jeong, M. H., Lopatin, Y., Lopes, R. D., Merkely, B., Martinez-Traba, M., Parikh, P. B., Parkhomenko, A., Ponikowski, P., Rossello, X., Schou, M., Simic, D., Steg, P. G., Szachniewicz, J., van der Meer, P., Vinereanu, D., Zieroth, S., Brueckmann, M., Sumin, M., Bhatt, D. L., Hernandez, A. F. & Butler, J. J Am Coll Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38588929
Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction. Wang, T., Shao, J., Kumar, S., Alnouri, M. W., Carvalho, J., Gunther, S., Krasel, C., Murphy, K. T., Bunemann, M., Offermanns, S. & Wettschureck, N. Circ Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38597112
Paradox of disproportionate atrial functional mitral regurgitation and survival after transcatheter edge-to-edge repair. Doldi, P. M., Stolz, L., Kassar, M., Kalbacher, D., Petronio, A. S., Butter, C., von Bardeleben, R. S., Iliadis, C., Grayburn, P. & Hausleiter, J. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38602287
Caught in action: how MSCs modulate atherosclerotic plaque. Egea, V. Front Cell Dev Biol 12, 1379091 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38601079
Mitral Valve Transcatheter Edge-to-Edge Repair: 1-Year Outcomes From the MiCLASP Study. Lurz, P., Schmitz, T., Geisler, T., Hausleiter, J., Eitel, I., Rudolph, V., Lubos, E., von Bardeleben, R. S., Brambilla, N., De Marco, F., Berti, S., Nef, H., Linke, A., Hengstenberg, C., Baldus, S., Spargias, K., Denti, P., Nickenig, G., Mollmann, H., Rottbauer, W., Praz, F., Butter, C., Reinthaler, M., Van Mieghem, N. M., Sherif, M., Swaans, M., Witkowski, A., Buch, M., Seidler, T., Iniguez, A., Thiele, H., Eissmann, M., Schreieck, J., Nabauer, M., Marcoff, L., Koulogiannis, K., Rassaf, T., Luedike, P. & Mi, C. S. I. JACC Cardiovasc Interv 17, 890-903 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38599692
Parenchymal cues define Vegfa-driven venous angiogenesis by activating a sprouting competent venous endothelial subtype. Preau, L., Lischke, A., Merkel, M., Oegel, N., Weissenbruch, M., Michael, A., Park, H., Gradl, D., Kupatt, C. & le Noble, F. Nat Commun 15, 3118 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38600061
Characteristics associated with occurrence of stroke in patients with infective endocarditis - a retrospective cohort study. Schuermann, H., von Rennenberg, R., Riegler, C., Rangus, I., Litmeier, S., Scheitz, J. F., Doehner, W., Audebert, H., Braemswig, T. B. & Nolte, C. H. Neurol Res Pract 6, 22 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38600573
Modulation of Antiplatelet Therapy in PCI-Treated Patients: A Rocky Road Toward More Individualized Treatment. Sibbing, D. J Am Coll Cardiol 83, 1382-1385 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38599714
AKAP12 Overexpression Affects Cardiac Function via PDE8. Subramanian, H. & Nikolaev, V. O. Circ Res 134, 1023-1025 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38603476
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment. von Haehling, S., Assmus, B., Bekfani, T., Dworatzek, E., Edelmann, F., Hashemi, D., Hellenkamp, K., Kempf, T., Raake, P., Schutt, K. A., Wachter, R., Schulze, P. C., Hasenfuss, G., Bohm, M. & Bauersachs, J. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38602566
Left atrial strain predicts the rhythm outcome in patients with persistent atrial fibrillation undergoing left atrial cryoablation during minimally invasive mitral valve repair. Yildirim, Y., Yildirim, S., Petersen, J., Alassar, Y., Sarwari, H., Sinning, C., Blankenberg, S., Reichenspurner, H. & Pecha, S. Front Cardiovasc Med11, 1373310 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38601047
Role of kinin receptors in skin pigmentation. Ferreira, J. C. P., Soley, B. S., Pawloski, P. L., Moreira, C. G., Pesquero, J. B., Bader, M., Calixto, J. B., Cabrini, D. A. & Otuki, M. F. Eur J Pharmacol 973, 176537 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38604546
Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation - Insights from Castle HTX. Moersdorf, M., Tijssen, J. G. P., Marrouche, N. F., Crijns, H., Costard-Jaeckle, A., Bergau, L., Hindricks, G., Dagres, N., Sossalla, S., Schramm, R., Fox, H., Fink, T., El Hamriti, M., Sciacca, V., Konietschke, F., Rudolph, V., Gummert, J., Sommer, P., Sohns, C. & Investigators, C. H. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/38604590
Comment on: 'Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart' by Saint-Martin Willer et al. Prüser, M., Wiedmann, F. & Schmidt, C. J Physiol 602, 2141-2142 (2024).
Transition from asymptomatic to symptomatic systolic chronic heart failure: rationale and design of TransitionCHF. Sandek, A., Edelmann, F., Gertler, C., Friede, T., Wachter, R., Hasenfuss, G. & Transition, C. H. F. c. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38606543
Characterization of Biomarkers of Thrombo-Inflammation in Patients with First-Diagnosed Atrial Fibrillation. Friebel, J., Wegner, M., Blobaum, L., Schencke, P. A., Jakobs, K., Puccini, M., Ghanbari, E., Lammel, S., Thevathasan, T., Moos, V., Witkowski, M., Landmesser, U. & Rauch-Krohnert, U. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38612918
Improvement in Visceral Adipose Tissue and LDL Cholesterol by High PUFA Intake: 1-Year Results of the NutriAct Trial. Meyer, N. M. T., Pohrt, A., Wernicke, C., Pletsch-Borba, L., Apostolopoulou, K., Haberbosch, L., Machann, J., Pfeiffer, A. F. H., Spranger, J. & Mai, K. Nutrients 16 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38613089
Optimization of Enzymatic and Chemical Decellularization of Native Porcine Heart Valves for the Generation of Decellularized Xenografts. Saeid Nia, M., Floder, L. M., Seiler, J. A., Puehler, T., Pommert, N. S., Berndt, R., Meier, D., Sellers, S. L., Sathananthan, J., Zhang, X., Hasler, M., Gorb, S. N., Warnecke, G. & Lutter, G. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38612836
Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study. Fabritz, L., Chua, W., Cardoso, V. R., Al-Taie, C., Borof, K., Suling, A., Krause, L., Kany, S., Magnussen, C., Wegscheider, K., Breithardt, G., Crijns, H., Camm, A. J., Gkoutos, G., Ellinor, P. T., Goette, A., Schotten, U., Wienhues-Thelen, U. H., Zeller, T., Schnabel, R. B., Zapf, A. & Kirchhof, P. Cardiovasc Res 120, 855-868 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38613511
Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium. Raisi-Estabragh, Z., Szabo, L., McCracken, C., Bulow, R., Aquaro, G. D., Andre, F., Le, T. T., Sucha, D., Condurache, D. G., Salih, A. M., Chadalavada, S., Aung, N., Lee, A. M., Harvey, N. C., Leiner, T., Chin, C. W. L., Friedrich, M. G., Barison, A., Dorr, M. & Petersen, S. E. JACC Cardiovasc Imaging 17, 746-762 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38613554
Thinner is better: Intentional weight loss and cardiovascular risk. Abraham, J., Butler, J. & Anker, S. D. Med 5, 275-277 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38614070
In Vitro Comparison of a Closed and Semi-closed Leaflet Design for Adult and Pediatric Transcatheter Heart Valves. Breitenstein-Attach, A., Steitz, M., Sun, X., Hao, Y., Kiekenap, J., Emeis, J., Tuladhar, S. R., Berger, F. & Schmitt, B. Ann Biomed Eng 52, 2051-2064 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38615078
Health economic evaluation of blended collaborative care for older multimorbid heart failure patients: study protocol. Derendorf, L., Stock, S., Simic, D., Shukri, A., Zelenak, C., Nagel, J., Friede, T., Herbeck Belnap, B., Herrmann-Lingen, C., Pedersen, S. S., Sorensen, J., Muller & On Behalf Of The Escape Consortium, D. Cost Eff Resour Alloc 22, 29 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38615050
Ca2+/calmodulin-dependent kinase IIdeltaC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak. Dewenter, M., Seitz, T., Steinbrecher, J. H., Westenbrink, B. D., Ling, H., Lehnart, S. E., Wehrens, X. H. T., Backs, J., Brown, J. H., Maier, L. S. & Neef, S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38616546
Mortality and rehospitalization in patients with pre-existing implantable pacemakers undergoing catheter ablation are related to increased comorbidity burden-data from the German Ablation Registry. Frommeyer, G., Reinke, F., Brachmann, J., Lewalter, T., Tilz, R. R., Willems, S., Straube, F., Akin, I., Lugenbiel, P., Hochadel, M., Senges, J. & Eckardt, L. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38619577
Nanopore Detection of METTL3-Dependent m6A-Modified mRNA Reveals a New Mechanism Regulating Cardiomyocyte Mitochondrial Metabolism. Rabolli, C. P., Naarmann-de Vries, I. S., Makarewich, C. A., Baskin, K. K., Dieterich, C. & Accornero, F. Circulation149, 1319-1322 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38620081
APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation. Lorenzo, J. P., Molla, L., Amro, E. M., Ibarra, I. L., Ruf, S., Neber, C., Gkougkousis, C., Ridani, J., Subramani, P. G., Boulais, J., Harjanto, D., Vonica, A., Di Noia, J. M., Dieterich, C., Zaugg, J. B. & Papavasiliou, F. N. Proc Natl Acad Sci U S A 121, e2312330121 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38625936
Prospects for Leveraging the Microbiota as Medicine for Hypertension. Durgan, D. J., Zubcevic, J., Vijay-Kumar, M., Yang, T., Manandhar, I., Aryal, S., Muralitharan, R. R., Li, H. B., Li, Y., Abais-Battad, J. M., Pluznick, J. L., Muller, D. N., Marques, F. Z. & Joe, B. Hypertension 81, 951-963 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630799
Trajectories of functional and structural myocardial parameters in post-COVID-19 syndrome-insights from mid-term follow-up by cardiovascular magnetic resonance. Groschel, J., Grassow, L., van Dijck, P., Bhoyroo, Y., Blaszczyk, E. & Schulz-Menger, J. Front Cardiovasc Med 11, 1357349 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38628318
Superparamagnetic Iron Oxide Nanoparticles Reprogram the Tumor Microenvironment and Reduce Lung Cancer Regrowth after Crizotinib Treatment. Horvat, N. K., Chocarro, S., Marques, O., Bauer, T. A., Qiu, R., Diaz-Jimenez, A., Helm, B., Chen, Y., Sawall, S., Sparla, R., Su, L., Klingmuller, U., Barz, M., Hentze, M. W., Sotillo, R. & Muckenthaler, M. U. ACS Nano 18, 11025-11041 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38626916
Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction: The REDUCE LAP-HF II Randomized Clinical Trial. Patel, R. B., Silvestry, F. E., Komtebedde, J., Solomon, S. D., Hasenfuss, G., Litwin, S. E., Borlaug, B. A., Price, M. J., Kawash, R., Hummel, S. L., Cutlip, D. E., Leon, M. B., van Veldhuisen, D. J., Rieth, A. J., McKenzie, S., Bugger, H., Mazurek, J. A., Kapadia, S. R., Vanderheyden, M., Ky, B. & Shah, S. J. JAMA Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630494
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human. Roh, J. D., Castro, C., Yu, A., Rana, S., Shahul, S., Gray, K. J., Honigberg, M. C., Ricke-Hoch, M., Iwamoto, Y., Yeri, A., Kitchen, R., Guerra, J. B., Hobson, R., Chaudhari, V., Chang, B., Sarma, A., Lerchenmuller, C., Al Sayed, Z. R., Diaz Verdugo, C., Xia, P., Skarbianskis, N., Zeisel, A., Bauersachs, J., Kirkland, J. L., Karumanchi, S. A., Gorcsan, J., 3rd, Sugahara, M., Damp, J., Hanley-Yanez, K., Ellinor, P. T., Arany, Z., McNamara, D. M., Investigators, I., Hilfiker-Kleiner, D. & Rosenzweig, A. Sci Transl Med 16, eadi0077 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630848
Clinical practice of continuous rhythm monitoring after embolic stroke of undetermined source. von Falkenhausen, A. S., Wischmann, J., Keidel, L. M., Kellnar, A. M., Thaler, R., Lackermair, K., Estner, H. L., Hoglinger, G., Massberg, S., Kaab, S., Kellert, L. & Sinner, M. F. PLoS One 19, e0302404 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38630693
Prediction of cardiac worsening through to cardiogenic shock in patients with acute heart failure. Beer, B. N., Kellner, C., Sundermeyer, J., Besch, L., Dettling, A., Kirchhof, P., Blankenberg, S., Magnussen, C. & Schrage, B. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38632837
Expanding the Chemical Space of Transforming Growth Factor-beta (TGFbeta) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives. Langle, D., Wojtowicz-Piotrowski, S., Priegann, T., Keller, N., Wesseler, F., Reckzeh, E. S., Steffens, K., Grathwol, C., Lemke, J., Flasshoff, M., Nather, C., Jonson, A. C., Link, A., Koch, O., Di Guglielmo, G. M. & Schade, D. ACS Pharmacol Transl Sci 7, 1069-1085 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38633593
Development of a Trusted Third Party at a Large University Hospital: Design and Implementation Study. Wundisch, E., Hufnagl, P., Brunecker, P., Meier Zu Ummeln, S., Trager, S., Kopp, M., Prasser, F. & Weber, J. JMIR Med Inform 12, e53075 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38632712
A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function. Ameri, P., Mercurio, V., Pollesello, P., Anker, M. S., Backs, J., Bayes-Genis, A., Borlaug, B. A., Burkhoff, D., Caravita, S., Chan, S. Y., de Man, F., Giannakoulas, G., Gonzalez, A., Guazzi, M., Hassoun, P. M., Hemnes, A. R., Maack, C., Madden, B., Melenovsky, V., Muller, O. J., Papp, Z., Pullamsetti, S. S., Rainer, P. P., Redfield, M. M., Rich, S., Schiattarella, G. G., Skaara, H., Stellos, K., Tedford, R. J., Thum, T., Vachiery, J. L., van der Meer, P., Van Linthout, S., Pruszczyk, P., Seferovic, P., Coats, A. J. S., Metra, M., Rosano, G., Rosenkranz, S. & Tocchetti, C. G. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38639017
Biomarker Periodic Repolarization Dynamics Indicates Enhanced Risk for Arrhythmias and Sudden Cardiac Death in Myocardial Infarction in Pigs. Bauer, J., Vlcek, J., Pauly, V., Hesse, N., Xia, R., Mo, L., Chivukula, A. S., Villgrater, H., Dressler, M., Hildebrand, B., Wolf, E., Rizas, K. D., Bauer, A., Kaab, S., Tomsits, P., Schuttler, D. & Clauss, S. J Am Heart Assoc, e032405 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38639363
Detecting m(6)A at single-molecular resolution via direct RNA sequencing and realistic training data. Chan, A., Naarmann-de Vries, I. S., Scheitl, C. P. M., Hobartner, C. & Dieterich, C. Nat Commun 15, 3323 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637518
Comprehensive characterization of cardiac contraction for improved post-infarction risk assessment. Corral Acero, J., Lamata, P., Eitel, I., Zacur, E., Evertz, R., Lange, T., Backhaus, S. J., Stiermaier, T., Thiele, H., Bueno-Orovio, A., Schuster, A. & Grau, V. Sci Rep 14, 8951 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637609
Associations between 47 anthropometric markers derived from a body scanner and relative fat-free mass in a population-based study. Dietzmann, M., Radke, D., Markus, M. R., Wiese, M., Volzke, H., Felix, S. B., Dorr, M., Bahls, M. & Ittermann, T. BMC Public Health 24, 1079 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637778
Late-stage meta-C-H alkylation of pharmaceuticals to modulate biological properties and expedite molecular optimisation in a single step. Guillemard, L., Ackermann, L. & Johansson, M. J. Nat Commun 15, 3349 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637496
Cardiometabolic and immune response to exercise training in patients with metabolic syndrome: retrospective analysis of two randomized clinical trials. Lechner, K., Kia, S., von Korn, P., Dinges, S. M., Mueller, S., Tjonna, A. E., Wisloff, U., Van Craenenbroeck, E. M., Pieske, B., Adams, V., Pressler, A., Landmesser, U., Halle, M. & Krankel, N. Front Cardiovasc Med 11, 1329633 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38638882
Microtubules: highway to ... arrhythmia? Liutkute, A., Prosser, B. L. & Voigt, N. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38637305
Impact of endothelial shear stress on coronary atherosclerotic plaque progression and composition: A meta-analysis and systematic review. Candreva, A., Buongiorno, A. L., Matter, M. A., Rizzini, M. L., Giacobbe, F., Ravetti, E., Giannino, G., Carmagnola, L., Gilhofer, T., Gallo, D., Chiastra, C., Stahli, B. E., Iannaccone, M., Morbiducci, U., Porto, I., De Ferrari, G. M. & D'Ascenzo, F. Int J Cardiol 407, 132061 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641263
Letter to the editor: fasting decreases expression of microRNAs linked to endothelial pathophysiology in mononuclear cells of healthy subjects. Honeycutt, D., Schmidt-Trucksass, A., Brink, M., Krankel, N. & Kropfl, J. M. Apoptosis 29, 935-937 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38642320
Tolerance induction through early feeding to prevent food allergy in infants and children with sensitization against food allergens (TIFFANI): rationale, study design, and methods of a randomized controlled trial. Kalb, B., Meixner, L., Heller, S., Dolle-Bierke, S., Roll, S., Tissen-Diabate, T., Lau, S., Forslund, S., Marenholz, I., Lee, Y. A., Thiel, A., Babina, M., Scheffel, J., Worm, M. & Beyer, K. Trials 25, 272 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641837
E-learning-an interventional element of the PRiVENT project to improve weaning expertise. Michels-Zetsche, J. D., Schubert-Haack, J., Tanck, K., Neetz, B., Iberl, G., Muller, M., Kempa, A., Joves, B., Rheinhold, A., Ghiani, A., Tsitouras, K., Schneider, A., Rauch, C., Gehrig, P., Biehler, E., Fleischauer, T., Britsch, S., Frerk, T., Szecsenyi, J., Herth, F. J. F., Trudzinski, F. C. & Group, P. R.-S. BMC Med Educ24, 420 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641835
S100A1: a promising therapeutic target for heart failure. Noll, D., Kehr, D., Most, P. & Ritterhoff, J. Expert Opin Ther Targets, 1-4 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38641766
Biomarkers of NRF2 signalling: Current status and future challenges. Morgenstern, C., Lastres-Becker, I., Demirdogen, B. C., Costa, V. M., Daiber, A., Foresti, R., Motterlini, R., Kalyoncu, S., Arioz, B. I., Genc, S., Jakubowska, M., Trougakos, I. P., Piechota-Polanczyk, A., Mickael, M., Santos, M., Kensler, T. W., Cuadrado, A. & Copple, I. M. Redox Biol 72, 103134 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38643749
Venous Vascular Closure System Versus Figure-of-Eight Suture Following Atrial Fibrillation Ablation - The STYLE-AF Study. Tilz, R., Feher, M., Vogler, J., Bode, K., Duta, A., Ortolan, A., Lopez, L. D., Kuchler, M., Mamaev, R., Lyan, E., Sommer, P., Braun, M., Sciacca, V., Demming, T., Maslova, V., Kuck, K. H., Heeger, C. H., Eitel, C. & Popescu, S. S. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38647070
Pathological high intraocular pressure induces glial cell reactive proliferation contributing to neuroinflammation of the blood-retinal barrier via the NOX2/ET-1 axis-controlled ERK1/2 pathway. Shi, X., Li, P., Herb, M., Liu, H., Wang, M., Wang, X., Feng, Y., van Beers, T., Xia, N., Li, H. & Prokosch, V. J Neuroinflammation 21, 105 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38649885
A parametric study on pulse duplicator design and valve hemodynamics. Smid, C. C., Pappas, G. A., Falk, V., Ermanni, P. & Cesarovic, N. Artif Organs (2024). https://www.ncbi.nlm.nih.gov/pubmed/38651352
Validation of the Klinrisk chronic kidney disease progression model in the FIDELITY population. Tangri, N., Ferguson, T., Leon, S. J., Anker, S. D., Filippatos, G., Pitt, B., Rossing, P., Ruilope, L. M., Farjat, A. E., Farag, Y. M. K., Schloemer, P., Lawatscheck, R., Rohwedder, K. & Bakris, G. L. Clin Kidney J 17, sfae052 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38650758
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathy. Wali, R., Xu, H., Cheruiyot, C., Saleem, H. N., Janshoff, A., Habeck, M. & Ebert, A. Biol Chem (2024). https://www.ncbi.nlm.nih.gov/pubmed/38651266
Randomized investigation of the MitraClip device in heart failure: Design and rationale of the RESHAPE-HF2 trial design. Anker, S. D., Friede, T., von Bardeleben, R. S., Butler, J., Fatima, K., Diek, M., Heinrich, J., Hasenfuss, G., Schillinger, W. & Ponikowski, P. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38654139
SRRM2 splicing factor modulates cell fate in early development. Carvalho, S., Zea-Redondo, L., Tang, T. C. C., Stachel-Braum, P., Miller, D., Caldas, P., Kukalev, A., Diecke, S., Grosswendt, S., Grosso, A. R. & Pombo, A. Biol Open 13 (2024). www.ncbi.nlm.nih.gov/pubmed/38656788
Karyopherin alpha2 is a maternal effect gene required for early embryonic development and female fertility in mice. Rother, F., Depping, R., Popova, E., Huegel, S., Heiler, A., Hartmann, E. & Bader, M. FASEB J 38, e23623 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38656660
Impacts of gene variants on drug effects-the foundation of genotype-guided pharmacologic therapy for long QT syndrome and short QT syndrome. Zhao, Z., Zang, X., Niu, K., Song, W., Wang, X., Mugge, A., Aweimer, A., Hamdani, N., Zhou, X., Zhao, Y., Akin, I. & El-Battrawy, I. EBioMedicine 103, 105108 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38653189
Economic Considerations of Cardiovascular Implantable Electronic Devices for The Treatment of Heart Failure. Elsner, C., Bettin, S., Tilz, R. & Häckl, D. Curr Heart Fail Rep 21, 186-193 (2024). https://pubmed.ncbi.nlm.nih.gov/38662154/
Pacing Using Cardiac Implantable Electric Device During TAVR: 10-Year Experience of a High-Volume Center. Haum, M., Steffen, J., Sadoni, S., Theiss, H., Stark, K., Estner, H., Massberg, S., Deseive, S. & Lackermair, K. JACC Cardiovasc Interv 17, 1020-1028 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38658116
Permanent Pacemaker Implantation and Long-Term Outcomes of Patients Undergoing Concomitant Mitral and Tricuspid Valve Surgery. Iribarne, A., Alabbadi, S. H., Moskowitz, A. J., Ailawadi, G., Badhwar, V., Gillinov, M., Thourani, V. H., Allen, K. B., Halkos, M. E., Patel, N. C., Kramer, R. S., D'Alessandro, D., Raymond, S., Chang, H. L., Gupta, L., Fenton, K. N., Taddei-Peters, W. C., Chu, M. W. A., Falk, V., Chikwe, J., Jeffries, N., Bagiella, E., O'Gara, P. T., Gelijns, A. C. & Egorova, N. N. J Am Coll Cardiol 83, 1656-1668 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38658105
Transportation Noise Pollution and Cardiovascular Health. Munzel, T., Molitor, M., Kuntic, M., Hahad, O., Roosli, M., Engelmann, N., Basner, M., Daiber, A. & Sorensen, M. Circ Res 134, 1113-1135 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38662856
Repurposing of an antiasthmatic drug may reduce NETosis and myocardial ischaemia/reperfusion injury. Amponsah-Offeh, M., Tual-Chalot, S. & Stellos, K. Eur Heart J 45, 1681-1683 (2024). https://pubmed.ncbi.nlm.nih.gov/38666350/
Targeting immune cell recruitment in atherosclerosis. Döring, Y., van der Vorst, E. P. C. & Weber, C. Nat Rev Cardiol (2024). https://pubmed.ncbi.nlm.nih.gov/38664575/
Body surface scan anthropometrics are associated with grip strength in the general population. Filges, B., Bahls, M., Radke, D., Gross, S., Ewert, R., Stubbe, B., Markus, M. R., Felix, S. B., Volzke, H., Dorr, M., Kohler, A. & Ittermann, T. Nutr Metab Cardiovasc Dis 34, 1864-1873 (2024). www.ncbi.nlm.nih.gov/pubmed/38664126
Categorization of Patients With Pulmonary Embolism by Charlson Comorbidity Index. Keller, K., Schmitt, V. H., Hahad, O., Espinola-Klein, C., Munzel, T., Lurz, P., Konstantinides, S. & Hobohm, L. Am J Med 137, 727-735 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38663792
Predictors of atrial fibrillation after embolic stroke of undetermined source in patients with implantable loop recorders. Kreimer, F., Aweimer, A., El-Battrawy, I., Labedi, A., Schneider, R., Haghikia, A., Mügge, A. & Gotzmann, M. Neurol Sci (2024). https://pubmed.ncbi.nlm.nih.gov/38664303/
Obesity-related inflammatory protein signature in cardiovascular clinical outcomes: results from the Gutenberg Health Study. Panova-Noeva, M., Koeck, T., Schoelch, C., Schulz, A., Prochaska, J. H., Michal, M., Strauch, K., Schuster, A. K., Lackner, K. J., Münzel, T., Hennige, A. M. & Wild, P. S. Obesity (Silver Spring) (2024). https://pubmed.ncbi.nlm.nih.gov/38664310/
Impact of Quantitative ST-T Analysis in Patients With Suspected Myocardial Infarction Presenting With Right Bundle Branch Block. Sorensen, N. A., Fakhri, Y., Gossling, A., Neumann, J. T., Haller, P. M., Toprak, B., Senftinger, J., Lehmacher, J., Scharlemann, L., Schock, A., Twerenbold, R., Westermann, D., Bille Andersson, H., Jensen, L. O., Holmvang, L. & Clemmensen, P. Am J Med 137, 770-775 e771 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38670517
Validation of a simple clinical tool for screening of acute lacunar stroke-A substudy of the WAKE-UP trial. Arba, F., Rinaldi, C., Jensen, M., Endres, M., Fiebach, J. B., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Thijs, V., Gerloff, C., Wardlaw, J. M. & Thomalla, G. Int J Stroke, 17474930241253987 (2024). https://pubmed.ncbi.nlm.nih.gov/38676549/
Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: data from a practice-based longitudinal cohort. Hobohm, L., Paschke, L. M., Farmakis, I. T., Barco, S., Partovi, S., Münzel, T., Konstantinides, S., Keller, K. & Below, M. J Thromb Haemost (2024). https://pubmed.ncbi.nlm.nih.gov/38677594/
Transcatheter Heart Valve Explantation for TAVR Failure (TAVR-Explant): A Heart Valve Collaboratory Expert Consensus Document on Operative Techniques. Kaneko, T., Bapat, V. N., Alakhtar, A. M., Zaid, S., George, I., Grubb, K. J., Harrington, K., Pirelli, L., Atkins, M., Desai, N. D., Bleiziffer, S., Noack, T., Modine, T., Denti, P., Kempfert, J., Ruge, H., Vitanova, K., Falk, V., Thourani, V. H., Bavaria, J. E., Reardon, M. J., Mack, M. J., Borger, M. A., Leon, M. B., Tang, G. H. L. & Fukuhara, S. J Thorac Cardiovasc Surg (2024). https://pubmed.ncbi.nlm.nih.gov/38677492/
Technological advancements in functional interpretation of genome-wide association studies (GWAS) findings: bridging the gap to clinical translation. Aherrahrou, R. & Kaikkonen, M. U. FEBS Lett (2024). https://pubmed.ncbi.nlm.nih.gov/38683017/
Anxiolytic effect of alamandine in male transgenic rats with low brain angiotensinogen is dependent on activation of MrgD receptors. Amado Costa, L., Oliveira Amaral, L. B., Mourão, F. A. G., Bader, M., Santos, R. A. S., Campagnole-Santos, M. J. & Kangussu, L. M. Horm Behav 163, 105551 (2024). https://pubmed.ncbi.nlm.nih.gov/38678724/
Competence and contributions of radiologists to cardiac CT and MR imaging across Europe. Dewey, M. Eur Radiol (2024). https://pubmed.ncbi.nlm.nih.gov/38683386/
Comparative electroencephalography analysis: Marathon runners during tapering versus sedentary controls reveals no significant differences. Moussiopoulou, J., Handrack-Bonnet, M., Pross, B., Pogarell, O., Keeser, D., Halle, M., Falkai, P., Scherr, J., Hasan, A. & Roeh, A. Brain Behav 14, e3480 (2024). https://pubmed.ncbi.nlm.nih.gov/38680019/
Multidisciplinary care of peripartum heart failure: A scientific statement of the Heart Failure Association of the ESC. Rakisheva, A., Sliwa, K., Bauersachs, J., Van Linthout, S., Chopra, V. K., Bayes-Genis, A., Fruzzetti, F., Cannatà, A., Deniau, B., Mebazaa, A., Savarese, G., Ray, R., Vitale, C., Metra, M. & Rosano, G. M. C. Eur J Heart Fail (2024). https://pubmed.ncbi.nlm.nih.gov/38679896/
Be prepared for the unexpected: Mind-stretching in ST-elevation myocardial infarction with situs inversus totalis. Viggiani, G., Ibrahim, T., Allescher, J. & Steger, A. Clin Case Rep 12, e8768 (2024). https://pubmed.ncbi.nlm.nih.gov/38681040/
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish. Cardeira-da-Silva, J., Wang, Q., Sagvekar, P., Mintcheva, J., Latting, S., Günther, S., Ramadass, R., Yekelchyk, M., Preussner, J., Looso, M., Junker, J. P. & Stainier, D. Y. R. Nat Commun 15, 3637 (2024). https://pubmed.ncbi.nlm.nih.gov/38684665/
A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy. Figueroa, K. P., Gross, C., Buena-Atienza, E., Paul, S., Gandelman, M., Kakar, N., Sturm, M., Casadei, N., Admard, J., Park, J., Zuhlke, C., Hellenbroich, Y., Pozojevic, J., Balachandran, S., Handler, K., Zittel, S., Timmann, D., Erdlenbruch, F., Herrmann, L., Feindt, T., Zenker, M., Klopstock, T., Dufke, C., Scoles, D. R., Koeppen, A., Spielmann, M., Riess, O., Ossowski, S., Haack, T. B. & Pulst, S. M. Nat Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/38684900
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function. Khani, S., Topel, H., Kardinal, R., Tavanez, A. R., Josephrajan, A., Larsen, B. D. M., Gaudry, M. J., Leyendecker, P., Egedal, N. M., Güller, A. S., Stanic, N., Ruppert, P. M. M., Gaziano, I., Hansmeier, N. R., Schmidt, E., Klemm, P., Vagliano, L. M., Stahl, R., Duthie, F., Krause, J. H., Bici, A., Engelhard, C. A., Gohlke, S., Frommolt, P., Gnad, T., Rada-Iglesias, A., Pradas-Juni, M., Schulz, T. J., Wunderlich, F. T., Pfeifer, A., Bartelt, A., Jastroch, M., Wachten, D. & Kornfeld, J. W. Nat Metab (2024). https://pubmed.ncbi.nlm.nih.gov/38684889/
Embolic strokes of undetermined source: a clinical consensus statement of the ESC Council on Stroke, the European Association of Cardiovascular Imaging and the European Heart Rhythm Association of the ESC. Ntaios, G., Baumgartner, H., Doehner, W., Donal, E., Edvardsen, T., Healey, J. S., Iung, B., Kamel, H., Kasner, S. E., Korompoki, E., Navi, B. B., Pristipino, C., Saba, L., Schnabel, R. B., Svennberg, E. & Lip, G. Y. H. Eur Heart J (2024). https://pubmed.ncbi.nlm.nih.gov/38685132/
März
Paper of the Month
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9
DZHK-Autor:innen: Felix A. Trogisch, Aya Abouissa, Merve Keles, Gesine M. Dittrich, Julio Cordero, Steve Grein, Shruthi Hemanna, Luka Nicin, Sofia-Iris Bibli, Stefanie Dimmeler, Gergana Dobreva, Joerg Heineke. Science Translational Medicine.
[Heart and blood: clonal hematopoiesis]. Dimmeler, S. & Zeiher, A. Herz 49, 105-110 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38424288
Alterations of iron homeostasis as a potential druggable driver of long COVID. Marques, O. & Muckenthaler, M. U. Nat Immunol 25, 387-389 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38429459
Rest and exercise-stress estimated pulmonary capillary wedge pressure using real-time free-breathing cardiovascular magnetic resonance imaging. Backhaus, S. J., Schulz, A., Lange, T., Evertz, R., Kowallick, J. T., Hasenfuss, G. & Schuster, A. J Cardiovasc Magn Reson 26, 101032 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38431079
Role of human Kallistatin in glucose and energy homeostasis in mice. Sandforth, L., Brachs, S., Reinke, J., Willmes, D., Sancar, G., Seigner, J., Juarez-Lopez, D., Sandforth, A., McBride, J. D., Ma, J. X., Haufe, S., Jordan, J. & Birkenfeld, A. L. Mol Metab 82, 101905 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38431218
Applying Machine Learning to Blood Count Data Predicts Sepsis with ICU Admission. Steinbach, D., Ahrens, P. C., Schmidt, M., Federbusch, M., Heuft, L., Lubbert, C., Nauck, M., Grundling, M., Isermann, B., Gibb, S. & Kaiser, T. Clin Chem 70, 506-515 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38431275
Trends of mortality rate in patients with congenital heart defects in Germany-analysis of nationwide data of the Federal Statistical Office of Germany. Abdul-Khaliq, H., Gomes, D., Meyer, S., von Kries, R., Wagenpfeil, S., Pfeifer, J. & Poryo, M. Clin Res Cardiol 113, 750-760 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38436738
Non-femoral focused transaxillary access in TAVI: GARY data analysis and future trends. Meertens, M. M., Adam, M., Beckmann, A., Ensminger, S., Frerker, C., Seiffert, M., Sinning, J. M., Bekeredjian, R., Walther, T., Beyersdorf, F., Mollmann, H., Balaban, U., Eghbalzadeh, K., Rudolph, T. K. & Bleiziffer, S. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38436739
Shortening in-hospital stay after transcatheter aortic valve implantation: a deja vu in percutaneous interventions. Mehilli, J. Eur Heart J 45, 963-965 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38437639
Impairment of the adrenergic reserve associated with exercise intolerance in a murine model of heart failure with preserved ejection fraction. Semmler, L., Jeising, T., Huettemeister, J., Bathe-Peters, M., Georgoula, K., Roshanbin, R., Sander, P., Fu, S., Bode, D., Hohendanner, F., Pieske, B., Annibale, P., Schiattarella, G. G., Oeing, C. U. & Heinzel, F. R. Acta Physiol (Oxf)240, e14124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38436094
Coronary Artery Calcium Score Predicts Major Adverse Cardiovascular Events in Stable Chest Pain. Biavati, F., Saba, L., Boussoussou, M., Kofoed, K. F., Benedek, T., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Stechovsky, C., Sakalyte, G., Cemerlic Adic, N., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M., Ilnicka-Suckiel, M., Plank, F., Knuuti, J., Faria, R., Schroder, S., Berry, C., Ruzsics, B., Rieckmann, N., Kubiak, C., Hansen, K. S., Muller-Nordhorn, J., Maurovich-Horvat, P., Sigvardsen, P. E., Benedek, I., Orr, C., Valente, F. X., Zvaigzne, L., Suchanek, V., Jankauskas, A., Adic, F., Woinke, M., Cadogan, D., Lecumberri, I., Thwaite, E., Kruk, M., Neskovic, A. N., Mancone, M., Kusmierz, D., Feuchtner, G., Pietila, M., Ribeiro, V. G., Drosch, T., Delles, C., Cau, R., Fisher, M., Merkely, B., Kragelund, C., Aurelian, R., Kelly, S., Garcia Del Blanco, B., Rubio, A., Szilveszter, B., Hove, J. D., Rodean, I., Regan, S., Cuellar Calabria, H., Edes, I. F., Larsen, L., Hodas, R., Napp, A. E., Haase, R., Feger, S., Mohamed, M., Serna-Higuita, L. M., Neumann, K., Dreger, H., Rief, M., Wieske, V., Budoff, M. J., Estrella, M., Martus, P., Bosserdt, M., Dewey, M. & Group, D. T. Radiology 310, e231557 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38441097
Organisation of paediatric echocardiography laboratories and governance of echocardiography services and training in Europe: current status, disparities, and potential solutions. A survey from the Association for European Paediatric and Congenital Cardiology (AEPC) imaging working group. Cantinotti, M., Voges, I., Miller, O., Raimondi, F., Grotenhuis, H., Bharucha, T., Garrido, A. O., Valsangiacomo, E., Roest, A., Sunnegardh, J., Salaets, T., Brun, H., Khraiche, D., Jossif, A., Schokking, M., Sebate-Rotes, A., Meyer-Szary, J., Deri, A., Koopman, L., Herberg, U., du Marchie Sarvaas, G., Leskinen, M., Tchana, B., Ten Harkel, A. D. J., Odemis, E., Morrison, L., Steimetz, M., Laser, K. T., Doros, G., Bellshan-Revell, H., Muntean, I., Anagostopoulou, A., Alpman, M. S., Hunter, L., Ojala, T., Bhat, M., Olejnik, P., Wacker, J., Bonello, B., Ramcharan, T., Greil, G., Marek, J., DiSalvo, G. & McMahon, C. J. Cardiol Young, 1-9 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38439642
Empagliflozin and risk of lower respiratory tract infection in heart failure with mildly reduced and preserved ejection fraction: An EMPEROR-Preserved analysis. Ferreira, J. P., Zannad, F., Packer, M., Filippatos, G., Pocock, S. J., Vasques-Novoa, F., Bohm, M., Butler, J. & Anker, S. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38439585
Long-term function of a novel autologous transcatheter pulmonary heart valve implant in an adult animal model. Kiekenap, J., Sun, X., Hao, Y., Steitz, M., Breitenstein-Attach, A., Emeis, J., Berger, F. & Schmitt, B. Catheter Cardiovasc Interv 103, 597-606 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38440908
Atlas of cardiac endothelial cell enhancer elements linking the mineralocorticoid receptor to pathological gene expression. Deng, L., Pollmeier, L., Bednarz, R., Cao, C., Laurette, P., Wirth, L., Mamazhakypov, A., Bode, C., Hein, L., Gilsbach, R. & Lother, A. Sci Adv 10, eadj5101 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38446896
Bi-Gaussian analysis reveals distinct education-related alterations in spherical equivalent and axial length-results from the Gutenberg Health Study. Hartmann, A., Grabitz, S. D., Wagner, F. M., Wild, P. S., Muller-Nurasyid, M., Lackner, K. J., Beutel, M. E., Munzel, T., Tuscher, O., Schattenberg, J. M., Pfeiffer, N. & Schuster, A. K. Graefes Arch Clin Exp Ophthalmol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38446204
Metabolic cost of unloading pedalling in different groups of patients with pulmonary hypertension and volunteers. Ittermann, T., Kaczmarek, S., Obst, A., Konemann, R., Bahls, M., Dorr, M., Stubbe, B., Heine, A., Habedank, D. & Ewert, R. Sci Rep 14, 5394 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38443426
Aortic arch blood flow measurements as a predictor of successful ECMO weaning in cardiogenic shock. Kellnar, A., Naumann, D., Scherer, C., Lusebrink, E., Joskowiak, D., Peterss, S., Hagl, C., Massberg, S., Orban, M. & Stremmel, C. Heliyon 10, e26773 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38444470
Serum metabolite signatures of cardiac function and morphology in individuals from a population-based cohort. Maushagen, J., Addin, N. S., Schuppert, C., Ward-Caviness, C. K., Nattenmuller, J., Adamski, J., Peters, A., Bamberg, F., Schlett, C. L., Wang-Sattler, R. & Rospleszcz, S. Biomark Res 12, 31 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38444025
Publisher Correction: A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Ferrell, M., Wang, Z., Anderson, J. T., Li, X. S., Witkowski, M., DiDonato, J. A., Hilser, J. R., Hartiala, J. A., Haghikia, A., Cajka, T., Fiehn, O., Sangwan, N., Demuth, I., Konig, M., Steinhagen-Thiessen, E., Landmesser, U., Tang, W. H. W., Allayee, H. & Hazen, S. L. Nat Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38448791
Reproducibility assessment of rapid strains in cardiac MRI: Insights and recommendations for clinical application. Halfmann, M. C., Hopman, L., Korperich, H., Blaszczyk, E., Groschel, J., Schulz-Menger, J., Salatzki, J., Andre, F., Friedrich, S. & Emrich, T. Eur J Radiol 174, 111386 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38447431
Recurrence of Atrial Fibrillation in Patients With New-Onset Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting. Herrmann, F. E. M., Taha, A., Nielsen, S. J., Martinsson, A., Hansson, E. C., Juchem, G. & Jeppsson, A. JAMA Netw Open 7, e241537 (2024). www.ncbi.nlm.nih.gov/pubmed/38451520
In preprints: Shh signaling activity predicts cardiac laterality in Astyanax mexicanus populations. Juan, T. & Ebnicher, G. Development 151 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38451186
Genome-wide characterization of circulating metabolic biomarkers. Karjalainen, M. K., Karthikeyan, S., Oliver-Williams, C., Sliz, E., Allara, E., Fung, W. T., Surendran, P., Zhang, W., Jousilahti, P., Kristiansson, K., Salomaa, V., Goodwin, M., Hughes, D. A., Boehnke, M., Fernandes Silva, L., Yin, X., Mahajan, A., Neville, M. J., van Zuydam, N. R., de Mutsert, R., Li-Gao, R., Mook-Kanamori, D. O., Demirkan, A., Liu, J., Noordam, R., Trompet, S., Chen, Z., Kartsonaki, C., Li, L., Lin, K., Hagenbeek, F. A., Hottenga, J. J., Pool, R., Ikram, M. A., van Meurs, J., Haller, T., Milaneschi, Y., Kahonen, M., Mishra, P. P., Joshi, P. K., Macdonald-Dunlop, E., Mangino, M., Zierer, J., Acar, I. E., Hoyng, C. B., Lechanteur, Y. T. E., Franke, L., Kurilshikov, A., Zhernakova, A., Beekman, M., van den Akker, E. B., Kolcic, I., Polasek, O., Rudan, I., Gieger, C., Waldenberger, M., Asselbergs, F. W., China Kadoorie Biobank Collaborative, G., Estonian Biobank Research, T., FinnGen, Hayward, C., Fu, J., den Hollander, A. I., Menni, C., Spector, T. D., Wilson, J. F., Lehtimaki, T., Raitakari, O. T., Penninx, B., Esko, T., Walters, R. G., Jukema, J. W., Sattar, N., Ghanbari, M., Willems van Dijk, K., Karpe, F., McCarthy, M. I., Laakso, M., Jarvelin, M. R., Timpson, N. J., Perola, M., Kooner, J. S., Chambers, J. C., van Duijn, C., Slagboom, P. E., Boomsma, D. I., Danesh, J., Ala-Korpela, M., Butterworth, A. S. & Kettunen, J. Nature 628, 130-138 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38448586
Bionic Nanocoating of Prosthetic Grafts Significantly Reduces Bacterial Growth. Pecha, S., Reuter, L., Ohdah, S., Petersen, J., Pahrmann, C., Aytar Celik, P., Cabuk, A., Reichenspurner, H. & Yildirim, Y. ACS Appl Mater Interfaces 16, 13534-13542 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38447594
Estimating potential cardiovascular health benefits of improved population level control of LDL cholesterol through a twice-yearly siRNA-based approach: A simulation study of a health-system level intervention. Ray, K. K., Gunn, L. H., Conde, L. G., Raal, F. J., Wright, R. S., Gosselin, N. H., Leiter, L. A., Koenig, W., Schwartz, G. G., Landmesser, U. & investigators, O. Atherosclerosis 391, 117472 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38447434
Noise annoyance and cardiovascular disease risk: results from a 10-year follow-up study. Hahad, O., Gilan, D., Michal, M., Tuscher, O., Chalabi, J., Schuster, A. K., Keller, K., Hobohm, L., Schmitt, V. H., Konig, J., Lackner, K. J., Wild, P., Schattenberg, J. M., Daiber, A. & Munzel, T. Sci Rep 14, 5619 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38454061
Biophysical Investigation of RNA ⋅ DNA : DNA Triple Helix and RNA : DNA Heteroduplex Formation by the lncRNAs MEG3 and Fendrr. Krause, N. M., Bains, J. K., Blechar, J., Richter, C., Bessi, I., Grote, P., Leisegang, M. S., Brandes, R. P. & Schwalbe, H. Chembiochem 25, e202400049 (2024). https://pubmed.ncbi.nlm.nih.gov/38456652/
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition. Ducommun, S., Jannig, P. R., Cervenka, I., Murgia, M., Mittenbuhler, M. J., Chernogubova, E., Dias, J. M., Jude, B., Correia, J. C., Van Vranken, J. G., Ocana-Santero, G., Porsmyr-Palmertz, M., McCann Haworth, S., Martinez-Redondo, V., Liu, Z., Carlstrom, M., Mann, M., Lanner, J. T., Teixeira, A. I., Maegdefessel, L., Spiegelman, B. M. & Ruas, J. L. Mol Metab 82, 101912 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38458566
Impact of depersonalization on the course of depression: longitudinal observations from the gutenberg health study. Michal, M., Wiltink, J., Tibubos, A. N., Wild, P. S., Munzel, T., Lackner, K., Pfeiffer, N., Konig, J., Gieswinkel, A., Beutel, M. & Kerahrodi, J. G. BMC Psychiatry 24, 196 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38459472
One small STEP, one giant leap: Semaglutide in the obese phenotype of heart failure with preserved ejection fraction. Sato, R. & von Haehling, S. Med 5, 181-183 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38460497
Association analysis between an epigenetic alcohol risk score and blood pressure. Bui, H., Keshawarz, A., Wang, M., Lee, M., Ratliff, S. M., Lin, L., Birditt, K. S., Faul, J. D., Peters, A., Gieger, C., Delerue, T., Kardia, S. L. R., Zhao, W., Guo, X., Yao, J., Rotter, J. I., Liu, D., Tavares, J. F., Pehlivan, G., Breteler, M. M. B., Karabegovic, I., Ochoa-Rosales, C., Voortman, T., Ghanbari, M., van Meurs, J. B. J., Nasr, M. K., Dorr, M., Grabe, H. J., London, S. J., Teumer, A., Waldenberger, M., Weir, D. R., Smith, J. A., Levy, D., Ma, J. & Liu, C. medRxiv (2024). https://www.ncbi.nlm.nih.gov/pubmed/38464320
Prescribing Patterns and Outcomes of Edoxaban in Atrial Fibrillation Patients From Asia - One-Year Data From the Global ETNA-AF Program. Choi, J. I., Kiatchoosakun, S., Jiampo, P., Tse, H. F., Soo, Y. O. Y., Wang, C. C., Lee, C. H., Pecen, L., Unverdorben, M., De Caterina, R. & Kirchhof, P. Circ Rep 6, 86-93 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38464984
Sex-specific structural and functional cardiac remodeling during healthy aging assessed by cardiovascular magnetic resonance. Grassow, L., Groschel, J., Saad, H., Kruger, L. D., Kuhnt, J., Muller, M., Hadler, T., Blaszczyk, E. & Schulz-Menger, J. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38466347
Incidence of microvascular dysfunction is increased in hyperlipidemic mice, reducing cerebral blood flow and impairing remote memory. Hernandez Torres, L. D., Rezende, F., Peschke, E., Will, O., Hovener, J. B., Spiecker, F., Ozorhan, U., Lampe, J., Stolting, I., Aherrahrou, Z., Kunne, C., Kusche-Vihrog, K., Matschl, U., Hille, S., Brandes, R. P., Schwaninger, M., Muller, O. J. & Raasch, W. Front Endocrinol (Lausanne) 15, 1338458 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38469142
Prognostic and diagnostic implications of impaired rest and exercise-stress left atrial compliance in heart failure with preserved ejection fraction: Insights from the HFpEF stress trial. Backhaus, S. J., Schulz, A., Lange, T., Schmidt-Schweda, L. S., Hellenkamp, K., Evertz, R., Kowallick, J. T., Kutty, S., Hasenfuss, G. & Schuster, A. Int J Cardiol 404, 131949 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38471649
Protein Kinase D Plays a Crucial Role in Maintaining Cardiac Homeostasis by Regulating Post-Translational Modifications of Myofilament Proteins. Herwig, M., Begovic, M., Budde, H., Delalat, S., Zhazykbayeva, S., Sieme, M., Schneider, L., Jaquet, K., Mugge, A., Akin, I., El-Battrawy, I., Fielitz, J. & Hamdani, N. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38474037
The Current Evidence of Pulmonary Embolism Response Teams and Their Role in Future. Hobohm, L., Farmakis, I. T., Duerschmied, D. & Keller, K. Hamostaseologie (2024). https://www.ncbi.nlm.nih.gov/pubmed/38471662
Optimal sample size allocation for two-arm superiority and non-inferiority trials with binary endpoints. Kirchner, M., Schupke, S. & Kieser, M. Pharm Stat (2024). https://www.ncbi.nlm.nih.gov/pubmed/38471740
Influence of a 7-day Transalpine Trail Run on cardiac biomarkers and myocardial function. Esefeld, K., Geisberger, M., Dinges, S. M., Hambrecht, J., Stegmuller, F., Rasper, M., Nadjiri, J., Roeschenthaler, F., Holdenrieder, S., Scharhag, J. & Halle, M. Scand J Med Sci Sports 34, e14590 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38483076
Characterization of anthracycline-induced cardiotoxicity by diffusion tensor magnetic resonance imaging. Lohr, D., Thiele, A., Stahnke, M., Braun, V. M., Klopfleisch, R., Klein, O., Dresen, S., Landmesser, U., Foryst-Ludwig, A., Kintscher, U., Schreiber, L. M. & Beyhoff, N. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38483601
Whole-body metabolic modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer's disease. Martinelli, F., Heinken, A., Henning, A. K., Ulmer, M. A., Hensen, T., Gonzalez, A., Arnold, M., Asthana, S., Budde, K., Engelman, C. D., Estaki, M., Grabe, H. J., Heston, M. B., Johnson, S., Kastenmuller, G., Martino, C., McDonald, D., Rey, F. E., Kilimann, I., Peters, O., Wang, X., Spruth, E. J., Schneider, A., Fliessbach, K., Wiltfang, J., Hansen, N., Glanz, W., Buerger, K., Janowitz, D., Laske, C., Munk, M. H., Spottke, A., Roy, N., Nauck, M., Teipel, S., Knight, R., Kaddurah-Daouk, R. F., Bendlin, B. B., Hertel, J. & Thiele, I. Sci Rep 14, 6095 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38480804
Ex vivo evaluation of 3 different right ventricular outflow tract substitutes. Saisho, H., Geisler, I., Scharfschwerdt, M., Sadat, N., Zhang, X., Puehler, T., Ensminger, S., Fujita, B. & Aboud, A. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38479833
Impact of epicardial adipose tissue on cardiac function and morphology in patients with diastolic dysfunction. Schulz, A., Backhaus, S. J., Lange, T., Evertz, R., Kutty, S., Kowallick, J. T., Hasenfuss, G. & Schuster, A. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38480481
Circadian assessment of heart failure using explainable deep learning and novel multi-parameter polar images. Alkhodari, M., Khandoker, A. H., Jelinek, H. F., Karlas, A., Soulaidopoulos, S., Arsenos, P., Doundoulakis, I., Gatzoulis, K. A., Tsioufis, K. & Hadjileontiadis, L. J. Comput Methods Programs Biomed 248, 108107 (2024). www.ncbi.nlm.nih.gov/pubmed/38484409
A supervised, externally validated machine learning model for artifact and drainage detection in high-resolution intracranial pressure monitoring data. Huo, S., Nelde, A., Meisel, C., Scheibe, F., Meisel, A., Endres, M., Vajkoczy, P., Wolf, S., Willms, J. F., Boss, J. M. & Keller, E. J Neurosurg 141, 509-517 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38489814
Correction: Definition, Classification, Diagnosis and Differential Diagnosis of Diabetes Mellitus: Update 2023. Pleus, S., Tytko, A., Landgraf, R., Heinemann, L., Werner, C., Muller-Wieland, D., Ziegler, A. G., Muller, U. A., Freckmann, G., Kleinwechter, H., Schleicher, E., Nauck, M. & Petersmann, A. Exp Clin Endocrinol Diabetes 132, e1 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38484786
Temporary extracorporeal life support: single-center experience with a new concept. Nersesian, G., Lewin, D., Ott, S., Schoenrath, F., Hrytsyna, Y., Starck, C., Spillmann, F., O'Brien, B., Falk, V., Potapov, E. & Lanmueller, P. Interdiscip Cardiovasc Thorac Surg (2024). https://www.ncbi.nlm.nih.gov/pubmed/38490254
Post-hoc standardisation of parametric T1 maps in cardiovascular magnetic resonance imaging: a proof-of-concept. Viezzer, D., Hadler, T., Groschel, J., Ammann, C., Blaszczyk, E., Kolbitsch, C., Hufnagel, S., Kranzusch-Gross, R., Lange, S. & Schulz-Menger, J. EBioMedicine 102, 105055 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38490103
Scrutinizing mechanical circulatory support in cardiogenic shock: Have we jumped the gun? Lusebrink, E., Lanz, H. & Thiele, H. Crit Care 28, 80 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38491468
Characterizing the immune response to myocardial infarction in pigs. Schnitter, F., Stangl, F., Noeske, E., Bille, M., Stadtmuller, A., Vogt, N., Sicklinger, F., Leuschner, F., Frey, A., Schreiber, L., Frantz, S., Beyersdorf, N., Ramos, G., Gladow, N. & Hofmann, U. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38491291
Editorial: Cardiovascular inflammaging: basic and translational aspects. Barcena, M. L., Aslam, M. & Ladilov, Y. Front Cardiovasc Med 11, 1385683 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38495941
A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. Nagarajan, P., Winkler, T. W., Bentley, A. R., Miller, C. L., Kraja, A. T., Schwander, K., Lee, S., Wang, W., Brown, M. R., Morrison, J. L., Giri, A., O'Connell, J. R., Bartz, T. M., de Las Fuentes, L., Gudmundsdottir, V., Guo, X., Harris, S. E., Huang, Z., Kals, M., Kho, M., Lefevre, C., Luan, J., Lyytikainen, L. P., Mangino, M., Milaneschi, Y., Palmer, N. D., Rao, V., Rauramaa, R., Shen, B., Stadler, S., Sun, Q., Tang, J., Theriault, S., van der Graaf, A., van der Most, P. J., Wang, Y., Weiss, S., Westerman, K. E., Yang, Q., Yasuharu, T., Zhao, W., Zhu, W., Altschul, D., Ansari, M. A. Y., Anugu, P., Argoty-Pantoja, A. D., Arzt, M., Aschard, H., Attia, J. R., Bazzanno, L., Breyer, M. A., Brody, J. A., Cade, B. E., Chen, H. H., Ida Chen, Y. D., Chen, Z., de Vries, P. S., Dimitrov, L. M., Do, A., Du, J., Dupont, C. T., Edwards, T. L., Evans, M. K., Faquih, T., Felix, S. B., Fisher-Hoch, S. P., Floyd, J. S., Graff, M., Gu, C., Gu, D., Hairston, K. G., Hanley, A. J., Heid, I. M., Heikkinen, S., Highland, H. M., Hood, M. M., Kahonen, M., Karvonen-Gutierrez, C. A., Kawaguchi, T., Kazuya, S., Kelly, T. N., Komulainen, P., Levy, D., Lin, H. J., Liu, P. Y., Marques-Vidal, P., McCormick, J. B., Mei, H., Meigs, J. B., Menni, C., Nam, K., Nolte, I. M., Pacheco, N. L., Petty, L. E., Polikowsky, H. G., Province, M. A., Psaty, B. M., Raffield, L. M., Raitakari, O. T., Rich, S. S., Riha, R. L., Risch, L., Risch, M., Ruiz-Narvaez, E. A., Scott, R. J., Sitlani, C. M., Smith, J. A., Sofer, T., Teder-Laving, M., Volker, U., Vollenweider, P., Wang, G., van Dijk, K. W., Wilson, O. D., Xia, R., Yao, J., Young, K. L., Zhang, R., Zhu, X., Below, J. E., Boger, C. A., Conen, D., Cox, S. R., Dorr, M., Feitosa, M. F., Fox, E. R., Franceschini, N., Gharib, S. A., Gudnason, V., Harlow, S. D., He, J., Holliday, E. G., Kutalik, Z., Lakka, T. A., Lawlor, D. A., Lee, S., Lehtimaki, T., Li, C., Liu, C. T., Magi, R., Matsuda, F., Morrison, A. C., Penninx, B. W., Peyser, P. A., Rotter, J. I., Snieder, H., Spector, T. D., Wagenknecht, L. E., Wareham, N. J., Zonderman, A. B., North, K. E., Fornage, M., Million Veteran, P., Hung, A. M., Manning, A. K., Gauderman, J., Chen, H., Munroe, P. B., Rao, D. C., van Heemst, D., Redline, S., Noordam, R. & Wang, H. medRxiv (2024). https://www.ncbi.nlm.nih.gov/pubmed/38496537
Biomarkers for predicting atrial fibrillation: An explorative sub-analysis of the randomised SCREEN-AF trial. Schmalstieg-Bahr, K., Gladstone, D. J., Hummers, E., Suerbaum, J., Healey, J. S., Zapf, A., Koster, D., Werhahn, S. M. & Wachter, R. Eur J Gen Pract30, 2327367 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38497412
Heart failure with Sarcopenia: A Bibliometric review from 1995 to 2022. You, Y., Meng, T., Lu, X., Zhu, X., Lv, M., Shou, X., He, Q. & Hu, Y. Heliyon 10, e27913 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38496860
CMR reference values of right ventricular volumetric variables in patients with hypoplastic left heart syndrome. Ballenberger, A., Caliebe, A., Krupickova, S., Uebing, A., Gabbert, D. D. & Voges, I. J Cardiovasc Magn Reson, 101038 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38499270
Generation of marmoset primordial germ cell-like cells under chemically defined conditions. Kurlovich, J., Rodriguez Polo, I., Dovgusha, O., Tereshchenko, Y., Cruz, C. R. V., Behr, R. & Gunesdogan, U. Life Sci Alliance 7 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38499329
Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials. Sun, M. L., Yao, W., Wang, X. Y., Gao, S., Varady, K. A., Forslund, S. K., Zhang, M., Shi, Z. Y., Cao, F., Zou, B. J., Sun, M. H., Liu, K. X., Bao, Q., Xu, J., Qin, X., Xiao, Q., Wu, L., Zhao, Y. H., Zhang, D. Y., Wu, Q. J. & Gong, T. T. EClinicalMedicine 70, 102519 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38500840
Takotsubo syndrome outcomes predicted by thyroid hormone signature: insights from cluster analysis of a multicentre registry. Aweimer, A., Dietrich, J. W., Santoro, F., Fabregas, M. C., Mugge, A., Nunez-Gil, I. J., Vazirani, R., Vedia, O., Patz, T., Ragnatela, I., Arcari, L., Volpe, M., Corbi-Pascual, M., Martinez-Selles, M., Almendro-Delia, M., Sionis, A., Uribarri, A., Thiele, H., Brunetti, N. D., Eitel, I., Stiermaier, T., Hamdani, N., Abumayyaleh, M., Akin, I. & El-Battrawy, I. EBioMedicine 102, 105063 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38502972
Comparative preclinical assessment of drug-coated balloons: a blessing and a curse for clinical translation. Joner, M. & Wild, L. EuroIntervention 20, e338-e340 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38506738
Comparison of two self-expanding transcatheter heart valves for degenerated surgical bioprostheses: the AVENGER multicentre registry. Kim, W. K., Seiffert, M., Ruck, A., Leistner, D. M., Dreger, H., Wienemann, H., Adam, M., Mollmann, H., Blumenstein, J., Eckel, C., Buono, A., Maffeo, D., Messina, A., Holzamer, A., Sossalla, S., Costa, G., Barbanti, M., Motta, S., Tamburino, C., von der Heide, I., Glasmacher, J., Sherif, M., Seppelt, P., Fischtlscherer, S., Walther, T., Castriota, F., Nerla, R., Frerker, C., Schmidt, T., Wolf, A., Adamaszek, M. M., Giannini, F., Vanhaverbeke, M., Van de Walle, S., Stammen, F., Toggweiler, S., Brunner, S., Mangieri, A., Gitto, M., Kaleschke, G., Ninios, V., Ninios, I., Hubner, J., Xhepa, E., Renker, M., Charitos, E. I., Joner, M. & Rheude, T. EuroIntervention 20, e363-e375 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38506737
The role of computed tomography prior to transcatheter aortic valve implantation: preprocedural planning and simultaneous coronary artery assessment. Renker, M. & Korosoglou, G. J Thorac Dis 16, 833-838 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38505069
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation. Vos, W. G., van Os, B. W., den Toom, M., Beckers, L., van Roomen, C., van Tiel, C. M., Mohapatra, B. C., Band, H., Nitz, K., Weber, C., Atzler, D., de Winther, M. P. J., Bosmans, L. A., Lutgens, E. & Seijkens, T. T. P. Front Immunol 15, 1297893 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38504977
Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets. Xu, X., Khunsriraksakul, C., Eales, J. M., Rubin, S., Scannali, D., Saluja, S., Talavera, D., Markus, H., Wang, L., Drzal, M., Maan, A., Lay, A. C., Prestes, P. R., Regan, J., Diwadkar, A. R., Denniff, M., Rempega, G., Ryszawy, J., Krol, R., Dormer, J. P., Szulinska, M., Walczak, M., Antczak, A., Matias-Garcia, P. R., Waldenberger, M., Woolf, A. S., Keavney, B., Zukowska-Szczechowska, E., Wystrychowski, W., Zywiec, J., Bogdanski, P., Danser, A. H. J., Samani, N. J., Guzik, T. J., Morris, A. P., Liu, D. J., Charchar, F. J., Human Kidney Tissue Resource Study, G. & Tomaszewski, M. Nat Commun 15, 2359 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38504097
Finerenone cardiovascular and kidney outcomes by age and sex: FIDELITY post hoc analysis of two phase 3, multicentre, double-blind trials. Bansal, S., Canziani, M. E. F., Birne, R., Anker, S. D., Bakris, G. L., Filippatos, G., Rossing, P., Ruilope, L. M., Farjat, A. E., Kolkhof, P., Lage, A., Brinker, M. & Pitt, B. BMJ Open 14, e076444 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38508632
Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner. ElBeck, Z., Hossain, M. B., Siga, H., Oskolkov, N., Karlsson, F., Lindgren, J., Walentinsson, A., Koppenhofer, D., Jarvis, R., Burli, R., Jamier, T., Franssen, E., Firth, M., Degasperi, A., Bendtsen, C., Menzies, R. I., Streckfuss-Bomeke, K., Kohlhaas, M., Nickel, A. G., Lund, L. H., Maack, C., Vegvari, A. & Betsholtz, C. Nat Commun 15, 2358 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38509128
Contemporary catheter ablation of complex atrial tachycardias after prior atrial fibrillation ablation: pulsed field versus radiofrequency current energy ablation guided by high-density mapping. Gunawardene, M. A., Harloff, T., Jularic, M., Dickow, J., Wahedi, R., Anwar, O., Wohlmuth, P., Gessler, N., Hartmann, J. & Willems, S. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38513110
Smart hospital: achieving interoperability and raw data collection from medical devices in clinical routine. Martens, E., Haase, H. U., Mastella, G., Henkel, A., Spinner, C., Hahn, F., Zou, C., Fava Sanches, A., Allescher, J., Heid, D., Strauss, E., Maier, M. M., Lachmann, M., Schmidt, G., Westphal, D., Haufe, T., Federle, D., Rueckert, D., Boeker, M., Becker, M., Laugwitz, K. L., Steger, A. & Muller, A. Front Digit Health 6, 1341475 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38510279
A latent clinical-anatomical dimension relating metabolic syndrome to brain structure and cognition. Petersen, M., Hoffstaedter, F., Nagele, F. L., Mayer, C., Schell, M., Rimmele, D. L., Zyriax, B. C., Zeller, T., Kuhn, S., Gallinat, J., Fiehler, J., Twerenbold, R., Omidvarnia, A., Patil, K. R., Eickhoff, S. B., Thomalla, G. & Cheng, B. Elife 12 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38512127
An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells. Ruan, D., Xuan, Y., Tam, T., Li, Z., Wang, X., Xu, S., Herrmann, D., Niemann, H., Lai, L., Gao, X., Nowak-Imialek, M. & Liu, P. Nat Protoc (2024). https://www.ncbi.nlm.nih.gov/pubmed/38509352
Secondary stroke prevention in people with atrial fibrillation: treatments and trials. Seiffge, D. J., Cancelloni, V., Raber, L., Paciaroni, M., Metzner, A., Kirchhof, P., Fischer, U., Werring, D. J., Shoamanesh, A. & Caso, V. Lancet Neurol 23, 404-417 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38508836
The homeobox transcription factor DUXBL controls exit from totipotency. Vega-Sendino, M., Luttmann, F. F., Olbrich, T., Chen, Y., Kuenne, C., Stein, P., Tillo, D., Carey, G. I., Zhong, J., Savy, V., Radonova, L., Lu, T., Saykali, B., Kim, K. P., Domingo, C. N., Schuler, L., Gunther, S., Bentsen, M., Bosnakovski, D., Scholer, H., Kyba, M., Maity, T. K., Jenkins, L. M., Looso, M., Williams, C. J., Kim, J. & Ruiz, S. Nat Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/38509386
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment. Kaiser, R., Gold, C., Joppich, M., Loew, Q., Akhalkatsi, A., Mueller, T. T., Offensperger, F., Droste Zu Senden, A., Popp, O., di Fina, L., Knottenberg, V., Martinez-Navarro, A., Eivers, L., Anjum, A., Escaig, R., Bruns, N., Briem, E., Dewender, R., Muraly, A., Akgol, S., Ferraro, B., Hoeflinger, J. K. L., Polewka, V., Khaled, N. B., Allgeier, J., Tiedt, S., Dichgans, M., Engelmann, B., Enard, W., Mertins, P., Hubner, N., Weckbach, L., Zimmer, R., Massberg, S., Stark, K., Nicolai, L. & Pekayvaz, K. Sci Adv 10, eadl1710 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38517968
Knock-out of dipeptidase CN2 in human proximal tubular cells disrupts dipeptide and amino acid homeostasis and para- and transcellular solute transport. Pfeffer, T., Krug, S. M., Kracke, T., Schurfeld, R., Colbatzky, F., Kirschner, P., Medert, R., Freichel, M., Schumacher, D., Bartosova, M., Zarogiannis, S. G., Muckenthaler, M. U., Altamura, S., Pezer, S., Volk, N., Schwab, C., Duensing, S., Fleming, T., Heidenreich, E., Zschocke, J., Hell, R., Poschet, G., Schmitt, C. P. & Peters, V. Acta Physiol (Oxf) 240, e14126 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38517248
Genetic ablation of Lmp2 increases the susceptibility for impaired cardiac function. Trogisch, F. A., Koser, F., Michel, S., Liem, D. A., Florea, B. I., Hecker, M. & Drews, O. Front Mol Biosci 11, 1148948 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38516190
FAPI-PET in Cardiovascular Disease. Higuchi, T., Serfling, S. E., Leistner, D. M., Speer, T. & Werner, R. A. Semin Nucl Med (2024). https://www.ncbi.nlm.nih.gov/pubmed/38519308
The Conceptual Definition of Sarcopenia: Delphi Consensus from the Global Leadership Initiative in Sarcopenia (GLIS). Kirk, B., Cawthon, P. M., Arai, H., Avila-Funes, J. A., Barazzoni, R., Bhasin, S., Binder, E. F., Bruyere, O., Cederholm, T., Chen, L. K., Cooper, C., Duque, G., Fielding, R. A., Guralnik, J., Kiel, D. P., Landi, F., Reginster, J. Y., Sayer, A. A., Visser, M., von Haehling, S., Woo, J., Cruz-Jentoft, A. J. & Global Leadership Initiative in Sarcopenia, g. Age Ageing 53 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38520141
Interpretability of bi-level variable selection methods. Buch, G., Schulz, A., Schmidtmann, I., Strauch, K. & Wild, P. S. Biom J 66, e2300063 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38519877
Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis. Hansen, C. E., Kamermans, A., Mol, K., Berve, K., Rodriguez-Mogeda, C., Fung, W. K., van Het Hof, B., Fontijn, R. D., van der Pol, S. M. A., Michalick, L., Kuebler, W. M., Kenkhuis, B., van Roon-Mom, W., Liedtke, W., Engelhardt, B., Kooij, G., Witte, M. E. & de Vries, H. E. J Neuroinflammation 21, 72 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521959
Quantification of ventricular stress in univentricular hearts during early childhood using age-independent zlog-NT-proBNP. Palm, J., Ono, M., Niedermaier, C., Horer, J., Hoffmann, G., Holdenrieder, S., Klawonn, F. & Ewert, P. Int J Cardiol 406, 131983 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521506
Author s Reply to Anterior Mitral Line and Pulsed Filed Ablation: different energy source, similar results? Reissmann, B., Wenzel, J. P., Lemoine, M. D., Rottner, L., My, I., Moser, F., Obergassel, J., Nies, M., Riess, J., Ismaili, D., Nikorowitsch, J., Kirchhof, P., Rillig, A., Metzner, A. & Ouyang, F. Heart Rhythm (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521383
Reply to the Editor- Anterior mitral line and pulsed field ablation: Different energy source, similar results? Reissmann, B., Wenzel, J. P., Lemoine, M. D., Rottner, L., My, I., Moser, F., Obergassel, J., Nies, M., Riess, J., Ismaili, D., Nikorowitsch, J., Kirchhof, P., Rillig, A., Metzner, A. & Ouyang, F. Heart Rhythm 21, 1255-1256 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38521383
A mini-review: phosphodiesterases in charge to balance intracellular cAMP during T-cell activation. Bielenberg, M., Kurelic, R., Frantz, S. & Nikolaev, V. O. Front Immunol15, 1365484 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38524120
Scrutinizing the Role of Venoarterial Extracorporeal Membrane Oxygenation: Has Clinical Practice Outpaced the Evidence? Lusebrink, E., Binzenhofer, L., Hering, D., Villegas Sierra, L., Schrage, B., Scherer, C., Speidl, W. S., Uribarri, A., Sabate, M., Noc, M., Sandoval, E., Erglis, A., Pappalardo, F., De Roeck, F., Tavazzi, G., Riera, J., Roncon-Albuquerque, R., Jr., Meder, B., Luedike, P., Rassaf, T., Hausleiter, J., Hagl, C., Zimmer, S., Westermann, D., Combes, A., Zeymer, U., Massberg, S., Schafer, A., Orban, M. & Thiele, H. Circulation 149, 1033-1052 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38527130
Mitophagy modulation for the treatment of cardiovascular diseases. Forte, M., D'Ambrosio, L., Schiattarella, G. G., Salerno, N., Perrone, M. A., Loffredo, F. S., Bertero, E., Pilichou, K., Manno, G., Valenti, V., Spadafora, L., Bernardi, M., Simeone, B., Sarto, G., Frati, G., Perrino, C., Sciarretta, S., Italian Society of Cardiology Working Group on, C. & Molecular Biology of the, H. Eur J Clin Invest 54, e14199 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38530070
Proteomic profiles of left atrial volume and its influence on response to spironolactone: Findings from the HOMAGE trial and STANISLAS cohort. Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H. P., Delles, C., Clark, A. L., Edelmann, F., Gonzalez, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A. J., Rossignol, P., Cleland, J. G. F., Zannad, F., Girerd, N., on behalf of the, H. T. C. & Investigators. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38528728
Effects of occlusal wear on 16-year progression of non-carious cervical lesions-Results of the study of health in Pomerania (SHIP-START). Giller, M., Holtfreter, B., Ruge, S., Volzke, H. & Bernhardt, O. J Oral Rehabil 51, 1184-1192 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38532285
Chimney Stenting vs BASILICA for Prevention of Acute Coronary Obstruction During Transcatheter Aortic Valve Replacement. Mangieri, A., Richter, I., Gitto, M., Abdelhafez, A., Bedogni, F., Lanz, J., Montorfano, M., Unbehaun, A., Giannini, F., Nerla, R., Taramasso, M., Ielasi, A., Rudolph, T., Ferlini, M., Ribichini, F., Poletti, E., Latib, A., Colombo, A., Van Mieghem, N. M., Thiele, H. & Abdel-Wahab, M. JACC Cardiovasc Interv 17, 742-752 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38538170
Clusters of longitudinal risk profile trajectories are associated with cardiometabolic diseases: Results from the population-based KORA cohort. Niedermayer, F., Schauberger, G., Rathmann, W., Klug, S. J., Thorand, B., Peters, A. & Rospleszcz, S. PLoS One 19, e0300966 (2024). www.ncbi.nlm.nih.gov/pubmed/38547172
Reverse cardio-oncology: is heart failure-mediated gut dysbiosis the mechanistic driver of colorectal cancer progression? Rangrez, A. Y. & Frey, N. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38547372
Non-invasive measurements of blood glucose levels by time-gating mid-infrared optoacoustic signals. Uluc, N., Glasl, S., Gasparin, F., Yuan, T., He, H., Justel, D., Pleitez, M. A. & Ntziachristos, V. Nat Metab (2024). https://www.ncbi.nlm.nih.gov/pubmed/38538980
Integration of a polygenic score into guideline-recommended prediction of cardiovascular disease. Li, L., Pang, S., Starnecker, F., Mueller-Myhsok, B. & Schunkert, H. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38551411
A streamlined pathway for transcatheter aortic valve implantation: the BENCHMARK study. Frank, D., Durand, E., Lauck, S., Muir, D. F., Spence, M., Vasa-Nicotera, M., Wood, D., Saia, F., Urbano-Carrillo, C. A., Bouchayer, D., Iliescu, V. A., Etienne, C. S., Leclercq, F., Auffret, V., Asmarats, L., Di Mario, C., Veugeois, A., Maly, J., Schober, A., Nombela-Franco, L., Werner, N., Gomez-Hospital, J. A., Mascherbauer, J., Musumeci, G., Meneveau, N., Meurice, T., Mahfoud, F., De Marco, F., Seidler, T., Leuschner, F., Joly, P., Collet, J. P., Vogt, F., Di Lorenzo, E., Kuhn, E., Disdier, V. P., Hachaturyan, V., Luske, C. M., Rakova, R., Wesselink, W., Kurucova, J., Bramlage, P., McCalmont, G. & Group, B. I. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38554125
Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies. Strohm, L., Daiber, A., Ubbens, H., Krishnankutty, R., Oelze, M., Kuntic, M., Hahad, O., Klein, V., Hoefer, I. E., von Kriegsheim, A., Kleinert, H., Atzler, D., Lurz, P., Weber, C., Wild, P. S., Munzel, T., Knosalla, C., Lutgens, E. & Daub, S. Basic Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38554187
First-in-human gene editing for lipid lowering: the initial results. Tual-Chalot, S. & Stellos, K. Cardiovasc Res 120, e5-e8 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38554379
Sex-specific trends in incidence of first myocardial infarction among people with and without diabetes between 1985 and 2016 in a German region. Claessen, H., Narres, M., Heier, M., Kvitkina, T., Linkohr, B., Wolff, G., Roden, M., Icks, A. & Peters, A. Cardiovasc Diabetol 23, 110 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38555466
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung. Dorner, P. J., Anandakumar, H., Rowekamp, I., Fiocca Vernengo, F., Millet Pascual-Leone, B., Krzanowski, M., Sellmaier, J., Bruning, U., Fritsche-Guenther, R., Pfannkuch, L., Kurth, F., Milek, M., Igbokwe, V., Lober, U., Gutbier, B., Holstein, M., Heinz, G. A., Mashreghi, M. F., Schulte, L. N., Klatt, A. B., Caesar, S., Wienhold, S. M., Offermanns, S., Mack, M., Witzenrath, M., Jordan, S., Beule, D., Kirwan, J. A., Forslund, S. K., Wilck, N., Bartolomaeus, H., Heimesaat, M. M. & Opitz, B. Nat Commun15, 2788 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38555356
Februar
Paper of the Month
Lung-to-Heart Nano-in-Micro Peptide Promotes Cardiac Recovery in a Pig Model of Chronic Heart Failure
DZHK-Autoren: Alessio Alogna, Uwe Primeßnig, Felix Hohendanner, Carsten Tschöpe, Burkert M. Pieske, Frank R. Heinzel. Journal of the American College of Cardiology 2024.
Genome engineering of a neuronal specific, optogenetic, induced pluripotent stem cell line. Aline Schmoll, K., Mager, T., Tse, T. P., Alameldeen, A., Zimmermann, W. H. & Zafeiriou, M. P. Stem Cell Res 75, 103317 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38295750
Transcatheter aortic valve replacement in heart failure. Parikh, P. B., Mack, M., Stone, G. W., Anker, S. D., Gilchrist, I. C., Kalogeropoulos, A. P., Packer, M., Skopicki, H. A. & Butler, J. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38297972
The Association of Off-Hour vs. On-Hour ICU Admission Time with Mortality in Patients with Cardiogenic Shock - a Retrospective Multicenter Analysis. Naumann, D., Fischer, J., Gmeiner, J., Lusebrink, E., Beer, B. N., Grieger, M., Giousouf, A., Schrage, B., Stremmel, C., Massberg, S., Orban, M. & Scherer, C. Eur Heart J Acute Cardiovasc Care (2024). https://www.ncbi.nlm.nih.gov/pubmed/38306600
The German version of the mHealth App Usability Questionnaire (GER-MAUQ): Translation and validation study in patients with cardiovascular disease. Tacke, T., Nohl-Deryk, P., Lingwal, N., Reimer, L. M., Starnecker, F., Guthlin, C., Gerlach, F. M., Schunkert, H., Jonas, S. & Muller, A. Digit Health 10, 20552076231225168 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38303970
Current and past depression as risk factors for incident type 2 diabetes mellitus and pre-diabetes in men and women: evidence from a longitudinal community cohort. Wicke, F. S., Otten, D., Schulz, A., Wild, P. S., Lackner, K. J., Munzel, T., Konig, J., Ernst, M., Wiltink, J., Reiner, I., Ghaemi Kerahrodi, J., Pfeiffer, N. & Beutel, M. E. Diabetol Metab Syndr 16, 34 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38303090
Adiposity influences on myocardial deformation: a cardiovascular magnetic resonance feature tracking study in people with overweight to obesity without established cardiovascular disease. Bolz, C., Blaszczyk, E., Mayr, T., Lim, C., Haufe, S., Jordan, J., Barckow, P., Groschel, J. & Schulz-Menger, J. Int J Cardiovasc Imaging 40, 643-654 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38308113
Stroke Related Brain-Heart Crosstalk: Pathophysiology, Clinical Implications, and Underlying Mechanisms. Fan, X., Cao, J., Li, M., Zhang, D., El-Battrawy, I., Chen, G., Zhou, X., Yang, G. & Akin, I. Adv Sci (Weinh), e2307698 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38308187
TransCatheter aortic valve implantation and fractional flow reserve-guided percutaneous coronary intervention versus conventional surgical aortic valve replacement and coronary bypass grafting for treatment of patients with aortic valve stenosis and multivessel or advanced coronary disease: The transcatheter valve and vessels trial (TCW trial): Design and rationale. Kedhi, E., Rroku, A., Hermanides, R. S., Dambrink, J. H., Singh, S., Berg, J. T., van Ginkel, D. J., Hudec, M., Amoroso, G., Amat-Santos, I. J., Andreas, M., Teles, R. C., Bonnet, G., Van Belle, E., Conradi, L., van Garsse, L., Wojakowski, W., Voudris, V., Sacha, J., Cervinka, P., Lipsic, E., Somi, S., Nombela-Franco, L., Postma, S., Piayda, K., De Luca, G., Malinofski, K. & Modine, T. Am Heart J 270, 86-94 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38309610
Association of plasma proteomics with incident coronary heart disease in individuals with and without type 2 diabetes: results from the population-based KORA study. Luo, H., Huemer, M. T., Petrera, A., Hauck, S. M., Rathmann, W., Herder, C., Koenig, W., Hoyer, A., Peters, A. & Thorand, B. Cardiovasc Diabetol 23, 53 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38310303
Body plethysmography - additional information on exercise capacity in patients with congenital heart disease? Hock, J., Bessar, M., Ewert, P. & Hager, A. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38315211
Delayed (68)Ga-FAPI-46 PET/MR imaging confirms ongoing fibroblast activation in patients after acute myocardial infarction. Kupusovic, J., Kessler, L., Kazek, S., Chodyla, M. K., Umutlu, L., Zarrad, F., Nader, M., Fendler, W. P., Varasteh, Z., Hermann, K., Dobrev, D., Wakili, R., Rassaf, T., Siebermair, J. & Rischpler, C. Int J Cardiol Heart Vasc 50, 101340 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38313450
Role of multidrug-resistant bacteria in weaning from invasive mechanical ventilation. Michels-Zetsche, J. D., Gassmann, V., Jasuja, J. K., Neetz, B., Hoger, P., Meis, J., Britsch, S., Sommerwerck, U., Fahndrich, S., Bornitz, F., Muller, M. M., Herth, F. J. F. & Trudzinski, F. C. Respir Res 25, 69 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38317197
Mineralocorticoid receptor antagonists for the prevention of atrial fibrillation in patients with and without heart failure: one more beneficial effect? Zurkan, D., Pitt, B. & Edelmann, F. Eur Heart J 45, 775-777 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38319069
Epicardial adipose tissue as an independent predictor of long-term outcome in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. Schulz, A., Beuthner, B. E., Bottiger, Z. M., Gersch, S. S., Lange, T., Gronwald, J., Evertz, R., Backhaus, S. J., Kowallick, J. T., Hasenfuss, G. & Schuster, A. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38324040
Secreted Protein Profiling of Human Aortic Smooth Muscle Cells Identifies Vascular Disease Associations. Aherrahrou, R., Baig, F., Theofilatos, K., Lue, D., Beele, A., Ord, T., Kaikkonen, M. U., Aherrahrou, Z., Cheng, Q., Ghosh, S. K. B., Karnewar, S., Karnewar, V., Finn, A. V., Owens, G. K., Joner, M., Mayr, M. & Civelek, M. Arterioscler Thromb Vasc Biol 44, 898-914 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38328934
Transcatheter mitral valve replacement at an inflection point: lessons learned and the path forward. Ludwig, S. & Granada, J. F. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38327011
Current treatment and immunomodulation strategies in Acute Myocarditis. Ferone, E., Segev, A., Tempo, E., Gentile, P., Elsanhoury, A., Baggio, C., Artico, J., Bhatti, P., Scott, P., Bobbio, E., Merlo, M., Ameri, P., Sinagra, G., Tschope, C., Bromage, D. & Cannata, A. J Cardiovasc Pharmacol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38335530
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction. Gotthardt, M. & Lehnart, S. E. Cardiovasc Res 120, 220-222 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38333928
Predictors of non-recovery from fatigue and cognitive deficits after COVID-19: a prospective, longitudinal, population-based study. Hartung, T. J., Bahmer, T., Chaplinskaya-Sobol, I., Deckert, J., Endres, M., Franzpotter, K., Geritz, J., Haeusler, K. G., Hein, G., Heuschmann, P. U., Hopff, S. M., Horn, A., Keil, T., Krawczak, M., Krist, L., Lieb, W., Maetzler, C., Montellano, F. A., Morbach, C., Neumann, C., Nurnberger, C., Russ, A. K., Schmidbauer, L., Schmidt, S., Schreiber, S., Steigerwald, F., Stork, S., Zoller, T., Maetzler, W., Finke, C. & Group, N. S. EClinicalMedicine 69, 102456 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38333368
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants. Knauer, C., Haltern, H., Schoger, E., Kugler, S., Roos, L., Zelarayan, L. C., Hasenfuss, G., Zimmermann, W. H., Wollnik, B. & Cyganek, L. Mol Ther Nucleic Acids 35, 102123 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38333672
Age-Associated Differences in Recovery from Exercise-Induced Muscle Damage. Li, D. C. W., Rudloff, S., Langer, H. T., Norman, K. & Herpich, C. Cells 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38334647
Analysis of Epicardial Adipose Tissue Texture in Relation to Coronary Artery Calcification in PCCT: The EAT Signature! Mundt, P., Hertel, A., Tharmaseelan, H., Norenberg, D., Papavassiliu, T., Schoenberg, S. O., Froelich, M. F. & Ayx, I. Diagnostics (Basel) 14 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38337793
A 10-year Follow-up Study of Association Between Uric Acid and Adverse Cardiovascular Events in Patients With Coronary Artery Disease. Ndrepepa, G., Kufner, S., Cassese, S., Joner, M., Xhepa, E., Wiebe, J., Sager, H. B., Kessler, T., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Am J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38336081
Increased Expression of Proinflammatory Genes in Peripheral Blood Cells Is Associated with Cardiac Cachexia in Patients with Heart Failure with Reduced Ejection Fraction. Sandek, A., Gertler, C., Valentova, M., Jauert, N., Wallbach, M., Doehner, W., von Haehling, S., Anker, S. D., Fielitz, J. & Volk, H. D. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38337428
Adherence and potential factors of adherence to a resistance, coordination and endurance training in older retirement home residents over 6 months. Weiss, M., Mende, E., Schaller, N., Krusemark, H., Spanier, B., Zelger, O., Bischof, J., Haller, B., Halle, M. & Siegrist, M. Scand J Med Sci Sports 34, e14576 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38339790
It is time to think about further optimization of the echocardiographic assessment of left ventricular responses to mitral regurgitation. Dandel, M. Int J Cardiol 401, 131841 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38340988
Childhood maltreatment and sleep apnea: Findings from a cross-sectional general population study. Spitzer, C., Weihs, A., Ewert, R., Stubbe, B., Penzel, T., Fietze, I., Volzke, H. & Grabe, H. J. J Psychosom Res 178, 111600 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38340571
Challenges and pitfalls during CRT implantation in patients with persistent left superior vena cava. Akdis, D., Vogler, J., Sieren, M. M., Molitor, N., Sasse, T., Phan, H. L., Bartoli, L., Grosse, N., Saguner, A. M., Eriksson, U., Duru, F., Hofer, D., Breitenstein, A., Tilz, R. R. & Winnik, S. J Interv Card Electrophysiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38345706
Complete revascularisation should be immediate in STEMI: pros and cons. Kastrati, A., Kessler, T., Rinaldi, R. & Brugaletta, S. EuroIntervention 20, e171-e173 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38343368
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse. Sommerfeld, L. C., Holmes, A. P., Yu, T. Y., O'Shea, C., Kavanagh, D. M., Pike, J. M., Wright, T., Syeda, F., Aljehani, A., Kew, T., Cardoso, V. R., Kabir, S. N., Hepburn, C., Menon, P. R., Broadway-Stringer, S., O'Reilly, M., Witten, A., Fortmueller, L., Lutz, S., Kulle, A., Gkoutos, G. V., Pavlovic, D., Arlt, W., Lavery, G. G., Steeds, R., Gehmlich, K., Stoll, M., Kirchhof, P. & Fabritz, L. J Physiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38345865
The Association Between C24:0/C16:0 Ceramide Ratio and Cardiorespiratory Fitness is Robust to Effect Modifications by Age and Sex. Zatloukal, J., Zylla, S., Markus, M. R. P., Ewert, R., Glaser, S., Volzke, H., Albrecht, D., Friedrich, N., Nauck, M., Peterson, L. R., Jiang, X., Schaffer, J. E., Felix, S. B., Dorr, M., Bahls, M. & Gross, S. Adv Biol (Weinh), e2300633 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38342586
Genomic attributes of airway commensal bacteria and mucosa. Cuthbertson, L., Lober, U., Ish-Horowicz, J. S., McBrien, C. N., Churchward, C., Parker, J. C., Olanipekun, M. T., Burke, C., McGowan, A., Davies, G. A., Lewis, K. E., Hopkin, J. M., Chung, K. F., O'Carroll, O., Faul, J., Creaser-Thomas, J., Andrews, M., Ghosal, R., Piatek, S., Willis-Owen, S. A. G., Bartolomaeus, T. U. P., Birkner, T., Dwyer, S., Kumar, N., Turek, E. M., William Musk, A., Hui, J., Hunter, M., James, A., Dumas, M. E., Filippi, S., Cox, M. J., Lawley, T. D., Forslund, S. K., Moffatt, M. F. & Cookson, W. O. C. Commun Biol 7, 171 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347162
Endothelial cells and macrophages as allies in the healthy and diseased brain. Denes, A., Hansen, C. E., Oezorhan, U., Figuerola, S., de Vries, H. E., Sorokin, L., Planas, A. M., Engelhardt, B. & Schwaninger, M. Acta Neuropathol 147, 38 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347307
Low on-clopidogrel ADP- and TRAP-6-induced platelet aggregation in patients with atrial fibrillation undergoing percutaneous coronary intervention: an observational pilot study. Gjermeni, D., Anfang, V., Vetter, H., Szabo, S., Hesselbarth, D., Gauchel, N., Siegel, P. M., Kaier, K., Kille, A., Franke, K., Leggewie, S., Trenk, D., Duerschmied, D., Bode, C., Westermann, D. & Olivier, C. B. J Thromb Thrombolysis 57, 361-369 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347374
Recommendations for optimal interdisciplinary management and healthcare settings for patients with rare neurological diseases. Graessner, H., Reinhard, C., Baumer, T., Baumgartner, A., Brockmann, K., Bruggemann, N., Bultmann, E., Erdmann, J., Heise, K., Hoglinger, G., Huning, I., Kaiser, F. J., Klein, C., Klopstock, T., Krageloh-Mann, I., Kraemer, M., Luedtke, K., Mucke, M., Musacchio, T., Nadke, A., Osmanovic, A., Ritter, G., Rose, K., Schippers, C., Schols, L., Schule, R., Schulz, J. B., Spross, J., Stasch, E., Wunderlich, G. & Munchau, A. Orphanet J Rare Dis 19, 62 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347616
Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy. Munoz, S., Bertolin, J., Jimenez, V., Jaen, M. L., Garcia, M., Pujol, A., Vila, L., Sacristan, V., Barbon, E., Ronzitti, G., El Andari, J., Tulalamba, W., Pham, Q. H., Ruberte, J., VandenDriessche, T., Chuah, M. K., Grimm, D., Mingozzi, F. & Bosch, F. Mol Metab 81, 101899 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38346589
Optogenetic confirmation of transverse-tubular membrane excitability in intact cardiac myocytes. Scardigli, M., Pasek, M., Santini, L., Palandri, C., Conti, E., Crocini, C., Campione, M., Loew, L. M., de Vries, A. A. F., Pijnappels, D. A., Pavone, F. S., Poggesi, C., Cerbai, E., Coppini, R., Kohl, P., Ferrantini, C. & Sacconi, L. J Physiol 602, 791-808 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38348881
Angiotensin Receptor-Neprilysin Inhibition (Sacubitril/Valsartan) Reduces Structural Arterial Stiffness in Middle-Aged Mice. Schellinger, I. N., Dannert, A., Hoffmann, A., Chodisetti, G., Mattern, K., Petzold, A., Kloting, N., Schuster, A., Wagenhauser, M. U., Emrich, F., Stumvoll, M., Hasenfuss, G. & Raaz, U. J Am Heart Assoc 13, e032641 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38348796
Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial. Sykes, R., Collison, D., Merkely, B., Kofoed, K. F., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Veselka, J., Sakalyte, G., Adic, N. C., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M., Ilnicka-Suckiel, M., Plank, F., Knuuti, J., Faria, R., Schroder, S., Berry, C., Saba, L., Ruzsics, B., Rieckmann, N., Kubiak, C., Hansen, K. S., Muller-Nordhorn, J., Maurovich-Horvat, P., Knudsen, A. D., Benedek, I., Orr, C., Valente, F. X., Zvaigzne, L., Horvath, M., Jankauskas, A., Adic, F., Woinke, M., Keane, S., Lecumberri, I., Thwaite, E., Laule, M., Kruk, M., Zivanic, A., Mancone, M., Kusmierz, D., Feuchtner, G., Pietila, M., Ribeiro, V. G., Drosch, T., Delles, C., Porcu, M., Fisher, M., Barany, T., Sorum, C., Aurelian, R., Kelly, S., Garcia Del Blanco, B., Rubio, A., Szilveszter, B., Abdulla, J., Rodean, I., Regan, S., Cuellar Calabria, H., Vecsey-Nagy, M., Jurlander, B., Hodas, R., Feger, S., Mohamed, M., Serna-Higuita, L. M., Neumann, K., Dreger, H., Rief, M., Wieske, V., Ferencik, M., Estrella, M., Bosserdt, M., Martus, P., Benedek, T., Dewey, M. & Group, D. T. Radiology 310, e230591 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38349247
Macrophages and endothelial cells in the neurovascular unit. Wenzel, J. & Schwaninger, M. Acta Neuropathol 147, 36 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38347168
Sodium-glucose cotransporter-2 inhibitors in heart failure patients across the range of body mass index: a systematic review and meta-analysis of randomized controlled trials. Adamou, A., Chlorogiannis, D. D., Kyriakoulis, I. G., Stamatiou, I., Koukousaki, D., Kardoutsos, I., Sagris, D., Doehner, W. & Ntaios, G. Intern Emerg Med 19, 565-573 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38353880
Guideline-directed medical therapy assessment in heart failure patients undergoing percutaneous mitral valve repair. Kresoja, K. P., Adamo, M., Rommel, K. P., Stolz, L., Karam, N., Giannini, C., Melica, B., von Bardeleben, R. S., Butter, C., Horn, P., Praz, F., Kalbacher, D., Iliadis, C., Thiele, H., Hausleiter, J., Metra, M. & Lurz, P. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38351672
New race-free creatinine- and cystatin C-based equations for the estimation of glomerular filtration rate and association with cardiovascular mortality in the AtheroGene study. Ntaios, G., Brederecke, J., Ojeda, F. M., Zeller, T., Blankenberg, S. & Schnabel, R. B. Intern Emerg Med 19, 697-703 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38351263
Neurological Disorders in Takotsubo Syndrome: Clinical Phenotypes and Outcomes. Santoro, F., Nunez Gil, I. J., Arcari, L., Vitale, E., Martino, T., El-Battrawy, I., Guerra, F., Novo, G., Mariano, E., Musumeci, B., Cacciotti, L., Caldarola, P., Montisci, R., Ragnatela, I., Cetera, R., Vedia, O., Blanco, E., Pais, J. L., Martin, A., Perez-Castellanos, A., Salamanca, J., Bartolomucci, F., Akin, I., Thiele, H., Eitel, I., Stiermaier, T. & Brunetti, N. D. J Am Heart Assoc, e032128 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38353238
Sex-related differences in patients presenting with heart failure-related cardiogenic shock. Sundermeyer, J., Kellner, C., Beer, B. N., Besch, L., Dettling, A., Bertoldi, L. F., Blankenberg, S., Dauw, J., Dindane, Z., Eckner, D., Eitel, I., Graf, T., Horn, P., Jozwiak-Nozdrzykowska, J., Kirchhof, P., Kluge, S., Linke, A., Landmesser, U., Luedike, P., Lusebrink, E., Majunke, N., Mangner, N., Maniuc, O., Mobius-Winkler, S., Nordbeck, P., Orban, M., Pappalardo, F., Pauschinger, M., Pazdernik, M., Proudfoot, A., Kelham, M., Rassaf, T., Scherer, C., Schulze, P. C., Schwinger, R. H. G., Skurk, C., Sramko, M., Tavazzi, G., Thiele, H., Villanova, L., Morici, N., Winzer, E. B., Westermann, D. & Schrage, B. Clin Res Cardiol 113, 612-625 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38353681
The role of thyroid function in borderline personality disorder and schizophrenia: a Mendelian Randomisation study. Babajide, O., Kjaergaard, A. D., Deng, W., Kus, A., Sterenborg, R., Asvold, B. O., Burgess, S., Teumer, A., Medici, M., German Borderline Genomics, C., Ellervik, C., Nick, B., Deloukas, P. & Marouli, E. Borderline Personal Disord Emot Dysregul 11, 2 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355654
Phenotypic and genome-wide studies on dicarbonyls: major associations to glomerular filtration rate and gamma-glutamyltransferase activity. Harrer, P., Inderhees, J., Zhao, C., Schormair, B., Tilch, E., Gieger, C., Peters, A., Johren, O., Fleming, T., Nawroth, P. P., Berger, K., Hermesdorf, M., Winkelmann, J., Schwaninger, M. & Oexle, K. EBioMedicine 101, 105007 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38354534
Clinical and serological characterization of acute pleuropericarditis suggests an autoinflammatory pathogenesis and highlights risk factors for recurrent attacks. Kaudewitz, D., John, L., Meis, J., Frey, N., Lorenz, H. M., Leuschner, F. & Blank, N. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38358415
Vascular dysfunction and arterial hypertension in experimental celiac disease are mediated by gut-derived inflammation and oxidative stress. Keppeler, K., Pesi, A., Lange, S., Helmstadter, J., Strohm, L., Ubbens, H., Kuntic, M., Kuntic, I., Mihalikova, D., Vujacic-Mirski, K., Rosenberger, A., Kuster, L., Frank, C., Oelze, M., Finger, S., Zakrzewska, A., Verdu, E., Wild, J., Karbach, S., Wenzel, P., Wild, P., Leistner, D., Munzel, T., Daiber, A., Schuppan, D. & Steven, S. Redox Biol 70, 103071 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38354629
A single-cell time-lapse of mouse prenatal development from gastrula to birth. Qiu, C., Martin, B. K., Welsh, I. C., Daza, R. M., Le, T. M., Huang, X., Nichols, E. K., Taylor, M. L., Fulton, O., O'Day, D. R., Gomes, A. R., Ilcisin, S., Srivatsan, S., Deng, X., Disteche, C. M., Noble, W. S., Hamazaki, N., Moens, C. B., Kimelman, D., Cao, J., Schier, A. F., Spielmann, M., Murray, S. A., Trapnell, C. & Shendure, J. Nature (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355799
Reply: miRNAs, Endothelin-1 and Endothelial Glycocalyx Disorders in Shock Severity in Postoperative Cardiac Surgery Patients. Roeschl, T., Falk, V., Schoenrath, F. & Meyer, A. J Am Coll Cardiol 83, e73 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355252
Assessment of deep learning segmentation for real-time free-breathing cardiac magnetic resonance imaging at rest and under exercise stress. Schilling, M., Unterberg-Buchwald, C., Lotz, J. & Uecker, M. Sci Rep 14, 3754 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38355969
From Gut to Heart: Role of Indole-3-Propionic Acid in HFpEF. Vacca, A. & Schiattarella, G. G. Circ Res 134, 390-392 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38359099
Association of serum magnesium with metabolic syndrome and the role of chronic kidney disease: A population-based cohort study with Mendelian randomization. Addin, N. S., Niedermayer, F., Thorand, B., Linseisen, J., Seissler, J., Peters, A. & Rospleszcz, S. Diabetes Obes Metab (2024). https://www.ncbi.nlm.nih.gov/pubmed/38361465
Alternative Renin-Angiotensin System. Bader, M., Muscha Steckelings, U., Alenina, N., Santos, R. A. S. & Ferrario, C. M. Hypertension (2024). https://www.ncbi.nlm.nih.gov/pubmed/38362781
NCoR1 limits angiogenic capacity by altering Notch signaling. Teichmann, T., Malacarne, P., Zehr, S., Gunther, S., Pfluger-Muller, B., Warwick, T. & Brandes, R. P. J Mol Cell Cardiol 188, 65-78 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38359551
Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration. Cordero, J., Elsherbiny, A., Wang, Y., Jürgensen, L., Constanty, F., Günther, S., Boerries, M., Heineke, J., Beisaw, A., Leuschner, F., Hassel, D. & Dobreva, G. Nucleic Acids Res 52, 4215-4233 (2024). Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration - PubMed (nih.gov)
Breathing danger: linking air pollution to cardiovascular disease and increased risk of abdominal aortic aneurysm. Hahad, O., Daiber, A. & Munzel, T. Eur Heart J 45, 1040-1042 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38366825
Patient satisfaction with coronary CT angiography versus invasive coronary angiography: results of a single-center randomized trial. Bosserdt, M., Wieske, V., Knebel, F., Mohamed, M. M. A., Feger, S., Dewey, M. & Schonenberger, E. Eur Radiol (2024). www.ncbi.nlm.nih.gov/pubmed/38367031
Tackling metabolic defects in HFpEF. Wang, R. & Schiattarella, G. G. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38367012
The ESR Essentials for the medical imaging community. Dewey, M. Eur Radiol 34, 2125-2126 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38369637
Use of class IC antiarrhythmic drugs in patients with structural heart disease and implantable cardioverter defibrillator. Zylla, M. M., Wolfes, J., Schleberger, R., Lawin, D., Kieser, M., Reinke, F., Eckardt, L., Rillig, A., Stellbrink, C., Thomas, D., Frey, N. & Lugenbiel, P. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38372753
Multivalent, calcium-independent binding of surfactant protein A and D to sulfated glycosaminoglycans of the alveolar epithelial glycocalyx. Avcibas, R., Vermul, A., Gluhovic, V., Boback, N., Arroyo, R., Kingma, P., Isasi-Campillo, M., Garcia-Ortega, L., Griese, M., Kuebler, W. M., Ochs, M., Lauster, D. & Lopez-Rodriguez, E. Am J Physiol Lung Cell Mol Physiol 326, L524-L538 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38375572
Generation of complex bone marrow organoids from human induced pluripotent stem cells. Frenz-Wiessner, S., Fairley, S. D., Buser, M., Goek, I., Salewskij, K., Jonsson, G., Illig, D., Zu Putlitz, B., Petersheim, D., Li, Y., Chen, P. H., Kalauz, M., Conca, R., Sterr, M., Geuder, J., Mizoguchi, Y., Megens, R. T. A., Linder, M. I., Kotlarz, D., Rudelius, M., Penninger, J. M., Marr, C. & Klein, C. Nat Methods (2024). https://www.ncbi.nlm.nih.gov/pubmed/38374263
Early action, lifelong impact: The crucial role of early detection, risk stratification and aggressive treatment of Familial Hypercholesterolemia. Sanin, V., Schmieder, R. S. & Koenig, W. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38376464
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., Rayner, N. W., Bocher, O., Arruda, A. L., Sonehara, K., Namba, S., Lee, S. S. K., Preuss, M. H., Petty, L. E., Schroeder, P., Vanderwerff, B., Kals, M., Bragg, F., Lin, K., Guo, X., Zhang, W., Yao, J., Kim, Y. J., Graff, M., Takeuchi, F., Nano, J., Lamri, A., Nakatochi, M., Moon, S., Scott, R. A., Cook, J. P., Lee, J. J., Pan, I., Taliun, D., Parra, E. J., Chai, J. F., Bielak, L. F., Tabara, Y., Hai, Y., Thorleifsson, G., Grarup, N., Sofer, T., Wuttke, M., Sarnowski, C., Gieger, C., Nousome, D., Trompet, S., Kwak, S. H., Long, J., Sun, M., Tong, L., Chen, W. M., Nongmaithem, S. S., Noordam, R., Lim, V. J. Y., Tam, C. H. T., Joo, Y. Y., Chen, C. H., Raffield, L. M., Prins, B. P., Nicolas, A., Yanek, L. R., Chen, G., Brody, J. A., Kabagambe, E., An, P., Xiang, A. H., Choi, H. 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Surgical or percutaneous treatment of mitral regurgitation: clip or cut? Lurz, P. & Kresoja, K. P. Eur Heart J 45, 950-951 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38379446
Definition, Classification, Diagnosis and Differential Diagnosis of Diabetes Mellitus: Update 2023. Pleus, S., Tytko, A., Landgraf, R., Heinemann, L., Werner, C., Muller-Wieland, D., Ziegler, A. G., Muller, U. A., Freckmann, G., Kleinwechter, H., Schleicher, E., Nauck, M. & Petersmann, A. Exp Clin Endocrinol Diabetes 132, 112-124 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378016
Counting cells in motion by quantitative real-time magnetic particle imaging. Remmo, A., Kosch, O., Kampen, L., Ludwig, A., Wiekhorst, F. & Lowa, N. Sci Rep 14, 4253 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378785
Impact of the operative technique on mid- and long-term results following paediatric heart transplantation. Rosenthal, L. L., Grinninger, C., Pozza, R. D., Fischer, M., Zimmerling, L., Ulrich, S. M., Kari, F. A., Haas, N. A., Michel, S., Horer, J. & Hagl, C. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378979
New pharmacological agents and novel cardiovascular pharmacotherapy strategies in 2023. Tamargo, J., Agewall, S., Borghi, C., Ceconi, C., Cerbai, E., Dan, G. A., Ferdinandy, P., Grove, E. L., Rocca, B., Magavern, E., Sulzgruber, P., Semb, A. G., Sossalla, S., Niessner, A., Kaski, J. C. & Dobrev, D. Eur Heart J Cardiovasc Pharmacother (2024). https://www.ncbi.nlm.nih.gov/pubmed/38379024
European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke. Wardlaw, J. M., Chabriat, H., de Leeuw, F. E., Debette, S., Dichgans, M., Doubal, F., Jokinen, H., Katsanos, A. H., Ornello, R., Pantoni, L., Pasi, M., Pavlovic, A. M., Rudilosso, S., Schmidt, R., Staals, J., Taylor-Rowan, M., Hussain, S. & Lindgren, A. G. Eur Stroke J 9, 5-68 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38380638
Acute Kidney Injury After Heart Transplantation: Risk Factors and Clinical Outcomes. Welz, F., Schoenrath, F., Friedrich, A., Wloch, A., Stein, J., Hennig, F., Ott, S. C., O'Brien, B., Falk, V., Knosalla, C. & Just, I. A. J Cardiothorac Vasc Anesth 38, 1150-1160 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38378323
TF-FVIIa PAR2-beta-Arrestin in Mouse Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection. Kespohl, M., Goetzke, C. C., Althof, N., Bredow, C., Kelm, N., Pinkert, S., Bukur, T., Bukur, V., Grunz, K., Kaur, D., Heuser, A., Mulleder, M., Sauter, M., Klingel, K., Weiler, H., Berndt, N., Gaida, M. M., Ruf, W. & Beling, A. Arterioscler Thromb Vasc Biol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38385286
First effectiveness data of lenvatinib and pembrolizumab as first-line therapy in advanced anaplastic thyroid cancer: a retrospective cohort study. Soll, D., Bischoff, P., Frisch, A., Jensen, M., Karadeniz, Z., Mogl, M. T., Horst, D., Penzkofer, T., Spranger, J., Keilholz, U. & Mai, K. BMC Endocr Disord 24, 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38383419
Thymic Atrophy and Immune Dysregulation in Infants with Complex Congenital Heart Disease. Bremer, S. J., Boxnick, A., Glau, L., Biermann, D., Joosse, S. A., Thiele, F., Billeb, E., May, J., Kolster, M., Hackbusch, R., Fortmann, M. I., Kozlik-Feldmann, R., Hubler, M., Tolosa, E., Sachweh, J. S. & Gieras, A. J Clin Immunol 44, 69 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38393459
Atrial fibrillation in the young: consider heritable conditions like short QT syndrome. Fabritz, L. & Lemoine, M. D. Cardiovasc Res 120, 437-439 (2024). Atrial fibrillation in the young: consider heritable conditions like short QT syndrome - PubMed (nih.gov)
Synchronous force and Ca(2+) measurements for repeated characterization of excitation-contraction coupling in human myocardium. Sun, Z., Lu, K., Kamla, C., Kameritsch, P., Seidel, T. & Dendorfer, A. Commun Biol 7, 220 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38388802
Personalised preinterventional risk stratification of mortality, length of stay and hospitalisation costs in transcatheter aortic valve implantation using a machine learning algorithm: a pilot trial. Zisiopoulou, M., Berkowitsch, A., Redlich, L., Walther, T., Fichtlscherer, S. & Leistner, D. M. Open Heart11 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38388188
The Evolving Role of Dendritic Cells in Atherosclerosis. Britsch, S., Langer, H., Duerschmied, D. & Becher, T. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38397127
Normative body mass-adjusted reference ranges of magnetic resonance imaging signs commonly used in diagnosing idiopathic intracranial hypertension in a healthy standard population. Kobrow, R., Gross, S., Fleischmann, R., Baldauf, J., Langner, S. & Strauss, S. Sci Rep 14, 4492 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38396059
Sex-specific associations of childhood maltreatment with obesity-related traits - The Study of Health in Pomerania (SHIP). Topfer, P., Siewert-Markus, U., Klinger-Konig, J., Grabe, H. J., Stracke, S., Dorr, M., Volzke, H., Ittermann, T. & Markus, M. R. P. Child Abuse Negl 149, 106704 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38395019
Pulmonary Vein Isolation Followed by Biatrial Ablation of Rotational Activity in Patients with Persistent Atrial Fibrillation: Results of the Cryo-Vest Study. Weipert, K. F., Hutter, J., Kuniss, M., Kahle, P., Yogarajah, J., Hain, A., Sperzel, J., Berkowitsch, A., Hamm, C. W. & Neumann, T. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38398432
ATF6 protects against protein misfolding during cardiac hypertrophy. Hofmann, C., Aghajani, M., Alcock, C. D., Blackwood, E. A., Sandmann, C., Herzog, N., Gross, J., Plate, L., Wiseman, R. L., Kaufman, R. J., Katus, H. A., Jakobi, T., Volkers, M., Glembotski, C. C. & Doroudgar, S. J Mol Cell Cardiol 189, 12-24 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38401179
The Chronic Dilemma of Chronic Total Occlusion Revascularization. Cassese, S. & Kastrati, A. Am J Cardiol 216, 95-97 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38401654
Circulating miR-let7a levels predict future diagnosis of chronic thromboembolic pulmonary hypertension. Kenneweg, F., Hobohm, L., Bang, C., Gupta, S. K., Xiao, K., Thum, S., Ten Cate, V., Rapp, S., Hasenfuss, G., Wild, P., Konstantinides, S., Wachter, R., Lankeit, M. & Thum, T. Sci Rep 14, 4514 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38402278
Effect of SGLT-2 inhibitors on arrhythmia events: insight from an updated secondary analysis of > 80,000 patients (the SGLT2i-Arrhythmias and Sudden Cardiac Death). Liao, J., Ebrahimi, R., Ling, Z., Meyer, C., Martinek, M., Sommer, P., Futyma, P., Di Vece, D., Schratter, A., Acou, W. J., Zhu, L., Kiuchi, M. G., Liu, S., Yin, Y., Purerfellner, H., Templin, C. & Chen, S. Cardiovasc Diabetol 23, 78 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38402177
Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis. Stone, G. W., Christiansen, E. H., Ali, Z. A., Andreasen, L. N., Maehara, A., Ahmad, Y., Landmesser, U. & Holm, N. R. Lancet 403, 824-837 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38401549
Histological assessment of cardiac amyloidosis in patients undergoing transcatheter aortic valve replacement. Beuthner, B. E., Elkenani, M., Evert, K., Mustroph, J., Jacob, C. F., Paul, N. B., Beissbarth, T., Zeisberg, E. M., Schnelle, M., Puls, M., Hasenfuss, G. & Toischer, K. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38407567
Body composition markers are associated with changes in inflammatory markers but not vice versa: A bi-directional longitudinal analysis in a population-based sample. Bibi, S., Naeem, M., Mahmoud Mousa, M. F., Bahls, M., Dorr, M., Friedrich, N., Nauck, M., Bulow, R., Volzke, H., Markus, M. R. & Ittermann, T. Nutr Metab Cardiovasc Dis 34, 1166-1174 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38403482
Lactate and Lactate Clearance as Predictors of One-Year Survival in Extracorporeal Cardiopulmonary Resuscitation - An International, Multicentre Cohort Study. Thevathasan, T., Gregers, E., Rasalingam Mork, S., Degbeon, S., Linde, L., Bonding Andreasen, J., Smerup, M., Eifer Moller, J., Hassager, C., Laugesen, H., Dreger, H., Brand, A., Balzer, F., Landmesser, U., Juhl Terkelsen, C., Flensted Lassen, J., Skurk, C. & Soholm, H. Resuscitation, 110149 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38403182
Sex Differences in Outcomes of Acute Myocardial Injury After Stroke. Rosso, M., Stengl, H., Ganeshan, R., Hellwig, S., Klammer, M. G., von Rennenberg, R., Bohme, S., Nolte, C. H., Audebert, H. J., Endres, M., Kasner, S. E. & Scheitz, J. F. J Am Heart Assoc 13, e032755 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38410952
Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial. Group, D. T., Bosserdt, M., Serna-Higuita, L. M., Feuchtner, G., Merkely, B., Kofoed, K. F., Benedek, T., Donnelly, P., Rodriguez-Palomares, J., Erglis, A., Stechovsky, C., Sakalyte, G., Adic, N. C., Gutberlet, M., Dodd, J. D., Diez, I., Davis, G., Zimmermann, E., Kepka, C., Vidakovic, R., Francone, M., Ilnicka-Suckiel, M., Plank, F., Knuuti, J., Faria, R., Schroder, S., Berry, C., Saba, L., Ruzsics, B., Rieckmann, N., Kubiak, C., Hansen, K. S., Muller-Nordhorn, J., Szilveszter, B., Sigvardsen, P. E., Benedek, I., Orr, C., Valente, F. X., Zvaigzne, L., Suchanek, V., Jankauskas, A., Adic, F., Woinke, M., Hensey, M., Lecumberri, I., Thwaite, E., Laule, M., Kruk, M., Neskovic, A. N., Mancone, M., Kusmierz, D., Pietila, M., Ribeiro, V. G., Drosch, T., Delles, C., Porcu, M., Fisher, M., Boussoussou, M., Kragelund, C., Aurelian, R., Kelly, S., Garcia Del Blanco, B., Rubio, A., Maurovich-Horvat, P., Hove, J. D., Rodean, I., Regan, S., Cuellar-Calabria, H., Molnar, L., Larsen, L., Hodas, R., Napp, A. E., Haase, R., Feger, S., Mohamed, M., Neumann, K., Dreger, H., Rief, M., Wieske, V., Estrella, M., Martus, P., Sox, H. C. & Dewey, M. JAMA Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38416472
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9. Trogisch, F. A., Abouissa, A., Keles, M., Birke, A., Fuhrmann, M., Dittrich, G. M., Weinzierl, N., Wink, E., Cordero, J., Elsherbiny, A., Martin-Garrido, A., Grein, S., Hemanna, S., Hofmann, E., Nicin, L., Bibli, S. I., Airik, R., Kispert, A., Kist, R., Quanchao, S., Kurschner, S. W., Winkler, M., Gretz, N., Mogler, C., Korff, T., Koch, P. S., Dimmeler, S., Dobreva, G. & Heineke, J. Sci Transl Med 16, eabq4581 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38416842
Higher Parametric Thyroid Feedback Quantile-based Index is a predictor of type 2 diabetes in a German population sample. Laclaustra, M., Alonso-Ventura, V., Schipf, S., Lou-Bonafonte, J. M., Dorr, M., Trincado-Aznar, P., Volzke, H., Nauck, M., Civeira, F. & Ittermann, T. J Clin Endocrinol Metab (2024). https://www.ncbi.nlm.nih.gov/pubmed/38421022
Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart. Waheed-Ullah, Q., Wilsdon, A., Abbad, A., Rochette, S., Bu'Lock, F., Hitz, M. P., Dombrowsky, G., Cuello, F., Brook, J. D. & Loughna, S. J Anat (2024). https://www.ncbi.nlm.nih.gov/pubmed/38419169
Novel drug therapies for atrial fibrillation. Wiedmann, F. & Schmidt, C. Nat Rev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38418746
Januar
Paper of the Month
In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector
DZHK-Autor:innen: Patrick Laurette, Can Cao, Deepak Ramanujam, Lisa Weiss, Eileen Furlong, Flavia de Rezende, Stefan Engelhardt, Ralf Gilsbach. Circulation Research 2024.
mRNA vaccines for COVID-19 are safe and clinically effective in patients with cardiac amyloidosis. Barzen, G., Rieber, F., Stangl, K., Hahn, K. & Spethmann, S. Vaccine (2023). https://www.ncbi.nlm.nih.gov/pubmed/38158299
The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. Carlantoni, C., Liekfeld, L. M. H., Hemkemeyer, S. A., Schreier, D., Saygi, C., Kurelic, R., Cardarelli, S., Kalucka, J., Schulte, C., Beerens, M., Mailer, R. K., Schaffer, T. E., Naro, F., Pellegrini, M., Nikolaev, V. O., Renne, T. & Frye, M. Dev Cell (2023). https://www.ncbi.nlm.nih.gov/pubmed/38159569
Efficacy of empagliflozin in heart failure with preserved ejection fraction according to frailty status in EMPEROR-Preserved. Coats, A. J. S., Butler, J., Tsutsui, H., Doehner, W., Filippatos, G., Ferreira, J. P., Bohm, M., Chopra, V. K., Verma, S., Nordaby, M., Iwata, T., Nitta, D., Ponikowski, P., Zannad, F., Packer, M. & Anker, S. D. J Cachexia Sarcopenia Muscle (2023). https://www.ncbi.nlm.nih.gov/pubmed/38158636
Impact of Clinical Phenogroup Diversity and Multiplicity: Impact on Mechanisms of Exercise Intolerance in Heart Failure with Preserved Ejection Fraction. Larson, K., Omar, M., Sorimachi, H., Omote, K., Alogna, A., Popovic, D., Tada, A., Doi, S., Naser, J., Reddy, Y. N. V., Redfield, M. M. & Borlaug, B. A. Eur J Heart Fail (2023). https://www.ncbi.nlm.nih.gov/pubmed/38156712
Heparin dosing in patients with Impella-supported cardiogenic shock. Vandenbriele, C., M'Pembele, R., Dannenberg, L., Metzen, D., Zako, S., Helten, C., Mourikis, P., Ignatov, D., Huhn, R., Balthazar, T., Adriaenssens, T., Vanassche, T., Meyns, B., Panoulas, V., Monteagudo-Vela, M., Arachchillage, D., Janssens, S., Scherer, C., Orban, M., Petzold, T., Horn, P., Jung, C., Zeus, T., Price, S., Westenfeld, R., Kelm, M. & Polzin, A. Int J Cardiol, 131690 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38160912
RNA-binding proteins in cardiovascular biology and disease: the beat goes on. Volkers, M., Preiss, T. & Hentze, M. W. Nat Rev Cardiol 21, 361-378 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38163813
Real-time cardiovascular magnetic resonance imaging for non-invasive characterisation of heart failure with preserved ejection fraction: final outcomes of the HFpEF stress trial. Backhaus, S. J., Schulz, A., Lange, T., Schmidt-Schweda, L. S., Evertz, R., Kowallick, J., Hasenfuss, G. & Schuster, A. Clin Res Cardiol 113, 496-508 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38170248
Toward accurate and fast velocity quantification with 3D ultrashort TE phase-contrast imaging. Degenhardt, K., Schmidt, S., Aigner, C. S., Kratzer, F. J., Seiter, D. P., Mueller, M., Kolbitsch, C., Nagel, A. M., Wieben, O., Schaeffter, T., Schulz-Menger, J. & Schmitter, S. Magn Reson Med 91, 1994-2009 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38174601
Loss of cardiac mitochondrial complex I persulfidation impairs NAD(+) homeostasis in aging. Drekolia, M. K., Karantanou, C., Wittig, I., Li, Y., Fuhrmann, D. C., Brune, B., Katsouda, A., Hu, J., Papapetropoulos, A. & Bibli, S. I. Redox Biol 69, 103014 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38171255
Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes. Paasche, A., Wiedmann, F., Kraft, M., Seibertz, F., Herlt, V., Blochberger, P. L., Javorszky, N., Beck, M., Weirauch, L., Seeger, T., Blank, A., Haefeli, W. E., Arif, R., Meyer, A. L., Warnecke, G., Karck, M., Voigt, N., Frey, N. & Schmidt, C. Basic Res Cardiol 119, 93-112 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38170280
Cyclophilin A is a ligand for RAGE in thrombo-inflammation. Seizer, P., von Ungern-Sternberg, S. N. I., Haug, V., Dicenta, V., Rosa, A., Butt, E., Nothel, M., Rohlfing, A. K., Sigle, M., Nawroth, P. P., Nussbaum, C., Sperandio, M., Kusch, C., Meub, M., Sauer, M., Munzer, P., Bieber, K., Stanger, A., Mack, A. F., Huber, R., Brand, K., Lehners, M., Feil, R., Poso, A., Krutzke, K., Schaffer, T. E., Nieswandt, B., Borst, O., May, A. E., Zernecke, A., Gawaz, M. & Heinzmann, D. Cardiovasc Res 120, 385-402 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38175781
Biomarkers in Primary Prevention: Steps beyond Established Risk Scores. Zeller, T., Shrivastava, A. & Karakas, M. Clin Chem 70, 355-357 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38169350
ILC2-mediated immune crosstalk in chronic (vascular) inflammation. Kral, M., van der Vorst, E. P. C., Surnov, A., Weber, C. & Doring, Y. Front Immunol 14, 1326440 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38179045
Treatment With an Interatrial Shunt in Heart Failure: 1-Year Outcomes of the PRELIEVE Study. Paitazoglou, C., Bergmann, M. W., Kilicaslan, B., Kilic, T., Bartunek, J., Pfister, R., Iliadis, C., Kaya, E. B. & Ozdemir, R. JACC Heart Fail 12, 591-594 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38180430
Noninvasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM. Rapohn, M., Cyganek, L., Voigt, N., Hasenfuss, G., Lehnart, S. E. & Wegener, J. W. Am J Physiol Heart Circ Physiol 326, H599-H611 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38180453
Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT). Roubille, F., Bouabdallaoui, N., Kouz, S., Waters, D. D., Diaz, R., Maggioni, A. P., Pinto, F. J., Gregoire, J. C., Gamra, H., Kiwan, G. S., Berry, C., Lopez-Sendon, J., Koenig, W., Delorme, L., Elbaz, M., Coste, P., Provencher, M., Bassevitch, Z., Blondeau, L., L'Allier, P. L., Guertin, M. C. & Tardif, J. C. Diabetes Care 47, 467-470 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38181203
Left-Ventricular Unloading With Impella During Refractory Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis. Thevathasan, T., Fureder, L., Fechtner, M., Mork, S. R., Schrage, B., Westermann, D., Linde, L., Gregers, E., Andreasen, J. B., Gaisendrees, C., Unoki, T., Axtell, A. L., Takeda, K., Vinogradsky, A. V., Goncalves-Teixeira, P., Lemaire, A., Alonso-Fernandez-Gatta, M., Sern Lim, H., Garan, A. R., Bindra, A., Schwartz, G., Landmesser, U. & Skurk, C. Crit Care Med 52, 464-474 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38180032
Polypharmacy in patients with multiple sclerosis and the impact on levels of care and therapy units. Bruggemann, F., Gross, S., Susse, M., Hok, P., Strauss, S., Ziemssen, T., Frahm, N., Zettl, U. K. & Grothe, M. Front Neurol 14, 1330066 (2023). https://www.ncbi.nlm.nih.gov/pubmed/38187151
Contact force sensing manual catheter versus remote magnetic navigation ablation of atrial fibrillation: a single-center comparison. Schlögl, S., Schlögl, K. S., Bengel, P., Haarmann, H., Bergau, L., Rasenack, E., Hasenfuss, G. & Zabel, M. Heart Vessels 39, 427-437 (2024). Contact force sensing manual catheter versus remote magnetic navigation ablation of atrial fibrillation: a single-center comparison - PubMed (nih.gov)
Control of cardiac contractions using Cre-lox and degron strategies in zebrafish. Juan, T., Bellec, M., Cardoso, B., Athea, H., Fukuda, N., Albu, M., Gunther, S., Looso, M. & Stainier, D. Y. R. Proc Natl Acad Sci U S A 121, e2309842121 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38194447
[Postmortem genetic analysis following sudden cardiac death : Background, approach, and future]. Kauferstein, S. & Beckmann, B. M. Herzschrittmacherther Elektrophysiol 35, 31-38 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38197940
Cardiovascular multimodality imaging in women. A scientific statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC. Almeida, A. G., Grapsa, J., Gemelli, A., Bucciarelli-Ducci, C., Gerber, B., Ajmone-Marsan, N., Bernard, A., Donal, E., Dweck, M. R., Haugaa, K. H., Hristova, K., Maceira, A., Mandoli, G. E., Mulvagh, S., Morrone, D., Plonska-Gosciniak, E., Sade, L. E., Schivalkar, B., Schulz-Menger, J., Shaw, L., Sitges, M., von Kemp, B., Pinto, F. J., Edvardsen, T., Petersen, S. E. & Cosyns, B. Eur Heart J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38198766
Characterization of Commercially Available Human Primary Alveolar Epithelial Cells. Herbst, C. J., Lopez-Rodriguez, E., Gluhovic, V., Schulz, S., Brandt, R., Timm, S., Abledu, J., Falivene, J., Pennitz, P., Kirsten, H., Nouailles, G., Witzenrath, M., Ochs, M. & Kuebler, W. M. Am J Respir Cell Mol Biol 70, 339-350 (2024).
Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli. Naeem, Z., Zukunft, S., Huard, A., Hu, J., Hammock, B. D., Weigert, A., Fromel, T. & Fleming, I. Biomed Pharmacother 171, 116127 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38198951
Detection of hypoplastic left heart syndrome anatomy from cardiovascular magnetic resonance images using machine learning. Gabbert, D. D., Petersen, L., Burleigh, A., Grazioli, S. B., Krupickova, S., Koch, R., Uebing, A. S., Santarossa, M. & Voges, I. MAGMA (2024). https://www.ncbi.nlm.nih.gov/pubmed/38214799
Systematic review and meta-analysis for the value of cardiac magnetic resonance strain to predict cardiac outcomes. Korosoglou, G., Sagris, M., Andre, F., Steen, H., Montenbruck, M., Frey, N. & Kelle, S. Sci Rep 14, 1094 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38212323
Contemporary risk assessment of aortic root injury for new-generation balloon-expandable transcatheter heart valves. Kim, W. K., Charitos, E., Renker, M., Hamm, C., Seidler, T., Hamm, C. W., Choi, Y. H. & Sossalla, S. Can J Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38215971
A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise. Methi, A., Islam, M. R., Kaurani, L., Sakib, M. S., Kruger, D. M., Pena, T., Burkhardt, S., Liebetanz, D. & Fischer, A. Mol Neurobiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38217668
Clinical interpretation of KCNH2 variants using a robust PS3/BS3 functional patch clamp assay. Thomson, K. L., Jiang, C., Richardson, E., Westphal, D. S., Burkard, T., Wolf, C. M., Vatta, M., Harrison, S. M., Ingles, J., Bezzina, C. R., Kroncke, B. M., Vandenberg, J. I. & Ng, C. A. HGG Adv, 100270 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38219013
Etiologies and predictors of mortality in an all-comer population of patients with non-ischemic heart failure. Göbel, S., Braun, A. S., Hahad, O., von Henning, U., Brandt, M., Keller, K., Gaida, M. M., Gori, T., Schultheiss, H. P., Escher, F., Münzel, T. & Wenzel, P. Clin Res Cardiol 113, 737-749 (2024). Etiologies and predictors of mortality in an all-comer population of patients with non-ischemic heart failure - PubMed (nih.gov)
Deep learning to estimate impaired glucose metabolism from Magnetic Resonance Imaging of the liver: An opportunistic population screening approach. Michel, L. J., Rospleszcz, S., Reisert, M., Rau, A., Nattenmueller, J., Rathmann, W., Schlett, C. L., Peters, A., Bamberg, F. & Weiss, J. PLOS Digit Health 3, e0000429 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38227569
STIGMA: Single-cell tissue-specific gene prioritization using machine learning. Balachandran, S., Prada-Medina, C. A., Mensah, M. A., Kakar, N., Nagel, I., Pozojevic, J., Audain, E., Hitz, M. P., Kircher, M., Sreenivasan, V. K. A. & Spielmann, M. Am J Hum Genet 111, 338-349 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38228144
Mask Continuous Positive Airway Pressure Increases Diaphragm Thickening Fraction in Healthy Subjects. Lindner, S., Teichert, J., Hoermann, C., Michels, J. D., Herth, F. J. F., Duerschmied, D. & Britsch, S. Respiration, 1-5 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38228112
Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function. Gersch, S., Lange, T., Beuthner, B. E., Elkenani, M., Paul, N., Schnelle, M., Zeisberg, E., Puls, M., Hasenfuss, G., Schuster, A. & Toischer, K. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38236417
Endogenous Nitric Oxide Can Enhance Oxidative Stress Caused by Air Pollutants and Explain Higher Susceptibility of Individuals with Inflammatory Disorders. Lelieveld, S., Lelieveld, J., Mishra, A., Daiber, A., Pozzer, A., Poschl, U. & Berkemeier, T. Environ Sci Technol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38235527
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements. Scholz, M., Horn, K., Pott, J., Wuttke, M., Kuhnapfel, A., Nasr, M. K., Kirsten, H., Li, Y., Hoppmann, A., Gorski, M., Ghasemi, S., Li, M., Tin, A., Chai, J. F., Cocca, M., Wang, J., Nutile, T., Akiyama, M., Asvold, B. O., Bansal, N., Biggs, M. L., Boutin, T., Brenner, H., Brumpton, B., Burkhardt, R., Cai, J., Campbell, A., Campbell, H., Chalmers, J., Chasman, D. I., Chee, M. L., Chee, M. L., Chen, X., Cheng, C. Y., Cifkova, R., Daviglus, M., Delgado, G., Dittrich, K., Edwards, T. L., Endlich, K., Michael Gaziano, J., Giri, A., Giulianini, F., Gordon, S. D., Gudbjartsson, D. F., Hallan, S., Hamet, P., Hartman, C. A., Hayward, C., Heid, I. M., Hellwege, J. N., Holleczek, B., Holm, H., Hutri-Kahonen, N., Hveem, K., Isermann, B., Jonas, J. B., Joshi, P. K., Kamatani, Y., Kanai, M., Kastarinen, M., Khor, C. C., Kiess, W., Kleber, M. E., Korner, A., Kovacs, P., Krajcoviechova, A., Kramer, H., Kramer, B. K., Kuokkanen, M., Kahonen, M., Lange, L. A., Lash, J. P., Lehtimaki, T., Li, H., Lin, B. M., Liu, J., Loeffler, M., Lyytikainen, L. P., Magnusson, P. K. E., Martin, N. G., Matsuda, K., Milaneschi, Y., Mishra, P. P., Mononen, N., Montgomery, G. W., Mook-Kanamori, D. O., Mychaleckyj, J. C., Marz, W., Nauck, M., Nikus, K., Nolte, I. M., Noordam, R., Okada, Y., Olafsson, I., Oldehinkel, A. J., Penninx, B., Perola, M., Pirastu, N., Polasek, O., Porteous, D. J., Poulain, T., Psaty, B. M., Rabelink, T. J., Raffield, L. M., Raitakari, O. T., Rasheed, H., Reilly, D. F., Rice, K. M., Richmond, A., Ridker, P. M., Rotter, J. I., Rudan, I., Sabanayagam, C., Salomaa, V., Schneiderman, N., Schottker, B., Sims, M., Snieder, H., Stark, K. J., Stefansson, K., Stocker, H., Stumvoll, M., Sulem, P., Sveinbjornsson, G., Svensson, P. O., Tai, E. S., Taylor, K. D., Tayo, B. O., Teren, A., Tham, Y. C., Thiery, J., Thio, C. H. L., Thomas, L. F., Tremblay, J., Tonjes, A., van der Most, P. J., Vitart, V., Volker, U., Wang, Y. X., Wang, C., Wei, W. B., Whitfield, J. B., Wild, S. H., Wilson, J. F., Winkler, T. W., Wong, T. Y., Woodward, M., Sim, X., Chu, A. Y., Feitosa, M. F., Thorsteinsdottir, U., Hung, A. M., Teumer, A., Franceschini, N., Parsa, A., Kottgen, A., Schlosser, P. & Pattaro, C. Nat Commun 15, 586 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38233393
Assessment of the cardiac output at rest and during exercise stress using real-time cardiovascular magnetic resonance imaging in HFpEF-patients. Schulz, A., Mittelmeier, H., Wagenhofer, L., Backhaus, S. J., Lange, T., Evertz, R., Kutty, S., Kowallick, J. T., Hasenfuss, G. & Schuster, A. Int J Cardiovasc Imaging (2024). https://www.ncbi.nlm.nih.gov/pubmed/38236362
C-reactive protein modifies lipoprotein(a)-related risk for coronary heart disease: the BiomarCaRE project. Arnold, N., Blaum, C., Gossling, A., Brunner, F. J., Bay, B., Ferrario, M. M., Brambilla, P., Cesana, G., Leoni, V., Palmieri, L., Donfrancesco, C., Padro, T., Andersson, J., Jousilahti, P., Ojeda, F., Zeller, T., Linneberg, A., Soderberg, S., Iacoviello, L., Gianfagna, F., Sans, S., Veronesi, G., Thorand, B., Peters, A., Tunstall-Pedoe, H., Kee, F., Salomaa, V., Schnabel, R. B., Kuulasmaa, K., Blankenberg, S., Koenig, W. & Waldeyer, C. Eur Heart J45, 1043-1054 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38240386
The obesity paradigm on outcome in heart failure with reduced ejection fraction. Doehner, W., Akyea, R. K. & Ntaios, G. Eur Heart J (2024). https://www.ncbi.nlm.nih.gov/pubmed/38240033
[Update on the treatment of aortic valve stenosis in symptomatic and asymptomatic patients]. Rheude, T., Pellegrini, C., Xhepa, E. & Joner, M. Herz (2024). https://www.ncbi.nlm.nih.gov/pubmed/38240775
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension. Santamans, A. M., Cicuendez, B., Mora, A., Villalba-Orero, M., Rajlic, S., Crespo, M., Vo, P., Jerome, M., Macias, A., Lopez, J. A., Leiva, M., Rocha, S. F., Leon, M., Rodriguez, E., Leiva, L., Pintor Chocano, A., Garcia Lunar, I., Garcia-Alvarez, A., Hernansanz-Agustin, P., Peinado, V. I., Barbera, J. A., Ibanez, B., Vazquez, J., Spinelli, J. B., Daiber, A., Oliver, E. & Sabio, G. Sci Adv10, eadk6524 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38241373
Artificial intelligence-derived risk score for mortality in secondary mitral regurgitation treated by transcatheter edge-to-edge repair: the EuroSMR risk score. Hausleiter, J., Lachmann, M., Stolz, L., Bedogni, F., Rubbio, A. P., Estevez-Loureiro, R., Raposeiras-Roubin, S., Boekstegers, P., Karam, N., Rudolph, V. & Euro, S. M. R. I. Eur Heart J 45, 922-936 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38243773
An altered plasma lipidome-phenome network characterizes heart failure with preserved ejection fraction. Jovanovic, N., Foryst-Ludwig, A., Klose, C., da Conceicao, C. R., Alasfar, L., Birkner, T., Forslund, S. K., Kintscher, U. & Edelmann, F. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38243357
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts. Shumliakivska, M., Luxan, G., Hemmerling, I., Scheller, M., Li, X., Muller-Tidow, C., Schuhmacher, B., Sun, Z., Dendorfer, A., Debes, A., Glaser, S. F., Muhly-Reinholz, M., Kirschbaum, K., Hoffmann, J., Nagel, E., Puntmann, V. O., Cremer, S., Leuschner, F., Abplanalp, W. T., John, D., Zeiher, A. M. & Dimmeler, S. Nat Commun 15, 606 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38242884
Single muscle assessment for diagnosing sarcopenia is inherently flawed. von Haehling, S. J Stroke Cerebrovasc Dis, 107533 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38242814
Layer-specific fast strain-encoded cardiac magnetic resonance imaging aids in the identification and discrimination of acute myocardial injury: a prospective proof-of-concept study. Weberling, L. D., Albert, D., Ochs, A., Ochs, M., Siry, D., Salatzki, J., Giannitsis, E., Frey, N., Riffel, J. & Andre, F. J Cardiovasc Magn Reson, 101001 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38244931
Neuromodulation interventions in the management of heart failure. Abdin, A., Lauder, L., Fudim, M., Abraham, W. T., Anker, S. D., Bohm, M. & Mahfoud, F. Eur J Heart Fail (2024). www.ncbi.nlm.nih.gov/pubmed/38247193
MRAS in coronary artery disease-Unchartered territory. Shah, P. W., Reinberger, T., Hashmi, S., Aherrahrou, Z. & Erdmann, J. IUBMB Life (2024). https://www.ncbi.nlm.nih.gov/pubmed/38251784
Comparison of Two Contemporary Quantitative Atherosclerotic Plaque Assessment Tools for Coronary Computed Tomography Angiography: Single-Center Analysis and Multi-Center Patient Cohort Validation. Weichsel, L., Giesen, A., Andre, F., Renker, M., Baumann, S., Breitbart, P., Beer, M., Maurovitch-Horvat, P., Szilveszter, B., Vattay, B., Buss, S. J., Marwan, M., Giannopoulos, A. A., Kelle, S., Frey, N. & Korosoglou, G. Diagnostics (Basel) 14 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38248031
Lipoprotein(a) and cardiovascular disease: sifting the evidence to guide future research. Kamstrup, P. R., Neely, R. D. G., Nissen, S., Landmesser, U., Haghikia, A., Costa-Scharplatz, M., Abbas, C. & Nordestgaard, B. G. Eur J Prev Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38253342
Correction: Samak et al. Dysregulation of Kruppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes. Int. J. Mol. Sci. 2023, 24, 2482. Samak, M., Kues, A., Kaltenborn, D., Klosener, L., Mietsch, M., Germena, G. & Hinkel, R. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38256279
An Overview of Different Vitamin D Compounds in the Setting of Adiposity. Spyksma, E. E., Alexandridou, A., Mai, K., Volmer, D. A. & Stokes, C. S. Nutrients 16 (2024). www.ncbi.nlm.nih.gov/pubmed/38257127
Circulating microRNA miR-425-5p Associated with Brain White Matter Lesions and Inflammatory Processes. Van der Auwera, S., Ameling, S., Wittfeld, K., Frenzel, S., Bulow, R., Nauck, M., Volzke, H., Volker, U. & Grabe, H. J. Int J Mol Sci 25 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38255959
Mechanical Circulatory Support Strategies in Takotsubo Syndrome with Cardiogenic Shock: A Systematic Review. von Mackensen, J. K. R., Zwaans, V. I. T., El Shazly, A., Van Praet, K. M., Heck, R., Starck, C. T., Schoenrath, F., Potapov, E. V., Kempfert, J., Jacobs, S., Falk, V. & Wert, L. J Clin Med 13 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38256608
Non-vitamin-K-antagonist oral anticoagulants (NOACs) after acute myocardial infarction: a network meta-analysis. Al Said, S., Kaier, K., Sumaya, W., Alsaid, D., Duerschmied, D., Storey, R. F., Gibson, C. M., Westermann, D. & Alabed, S. Cochrane Database Syst Rev1, CD014678 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38264795
European Society of Cardiology Quality indicators for the care and outcomes of adults undergoing transcatheter aortic valve implantation. Ali, N., Aktaa, S., Younsi, T., Beska, B., Batra, G., Blackman, D. J., James, S., Ludman, P., Mamas, M. A., Abdel-Wahab, M., Borregaard, B., Iung, B., Joner, M., Kunadian, V., Modine, T., Neylon, A., Petronio, A. S., Pibarot, P., Popescu, B. A., Sabate, M., Stortecky, S., Teles, R. C., Treede, H. & Gale, C. P. Eur Heart J Qual Care Clin Outcomes (2024). https://www.ncbi.nlm.nih.gov/pubmed/38262740
Disturbed atrial metabolism, shear stress, and cardiac load AF after ablation: AXAFA biomolecule study. Chua, W., Khashaba, A., Canagarajah, H., Nielsen, J. C., di Biase, L., Haeusler, K. G., Hindricks, G., Mont, L., Piccini, J., Schnabel, R. B., Schotten, U., Wienhues-Thelen, U. H., Zeller, T., Fabritz, L. & Kirchhof, P. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38266130
Patterns in acute aortic dissection and a connection to meteorological conditions in Germany. Kurz, S. D., Mahlke, H., Graw, K., Prasse, P., Falk, V., Knosalla, C. & Matzarakis, A. PLoS One 19, e0296794 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38265976
Aspirin loading and coronary no-reflow after percutaneous coronary intervention in patients with acute myocardial infarction. Ndrepepa, G., Cassese, S., Xhepa, E., Joner, M., Sager, H. B., Kufner, S., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Eur J Clin Invest, e14173 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38264959
Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes. Schmidt, J., Kaulfuss, S., Ott, H., Gaubert, M., Reintjes, N., Bremmer, F., Dreha-Kulaczewski, S., Stroebel, P., Yigit, G. & Wollnik, B. Hum Genet (2024). https://www.ncbi.nlm.nih.gov/pubmed/38265560
Efficacy and safety of CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: Rationale and design of the HF-REVERT trial. Bauersachs, J., Solomon, S. D., Anker, S. D., Antorrena-Miranda, I., Batkai, S., Viereck, J., Rump, S., Filippatos, G., Granzer, U., Ponikowski, P., de Boer, R. A., Vardeny, O., Hauke, W. & Thum, T. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38269451
Serotonin Transporter-dependent Histone Serotonylation in Placenta Contributes to the Neurodevelopmental Transcriptome. Chan, J. C., Alenina, N., Cunningham, A. M., Ramakrishnan, A., Shen, L., Bader, M. & Maze, I. J Mol Biol 436, 168454 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38266980
Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD-results from COSYCONET. Fahndrich, S., Herr, C., Teuteberg, S., Alter, P., Sohler, S., Soriano, D., Classen, J., Adams, J., Weinhold, V., Watz, H., Waschki, B., Zeller, T., Eichenlaub, M., Trudzinski, F. C., Michels, J. D., Omlor, A., Seiler, F., Moneke, I., Biertz, F., Stolz, D., Welte, T., Kauczor, H. U., Kahnert, K., Jorres, R. A., Vogelmeier, C. F., Bals, R. & German, C. C. Respir Res 25, 56 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38267944
Integration of implantable device therapy in patients with heart failure. A clinical consensus statement from the Heart Failure Association (HFA) and European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC). Mullens, W., Dauw, J., Gustafsson, F., Mebazaa, A., Steffel, J., Witte, K. K., Delgado, V., Linde, C., Vernooy, K., Anker, S. D., Chioncel, O., Milicic, D., Hasenfuss, G., Ponikowski, P., Stephan von Bardeleben, R., Koehler, F., Ruschitzka, F., Damman, K., Schwammenthal, E., Testani, J. M., Zannad, F., Bohm, M., Cowie, M. R., Dickstein, K., Jaarsma, T., Filippatos, G., Volterrani, M., Thum, T., Adamopoulos, S., Cohen-Solal, A., Moura, B., Rakisheva, A., Ristic, A., Bayes-Genis, A., Van Linthout, S., Tocchetti, C. G., Savarese, G., Skouri, H., Adamo, M., Amir, O., Yilmaz, M. B., Simpson, M., Tokmakova, M., Gonzalez, A., Piepoli, M., Seferovic, P., Metra, M., Coats, A. J. S. & Rosano, G. M. C. Eur J Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38269474
Exercise training and high-sensitivity cardiac troponin-I in patients with heart failure with reduced ejection fraction. Riveland, E., Valborgland, T., Ushakova, A., Skadberg, O., Karlsen, T., Hole, T., Stoylen, A., Dalen, H., Videm, V., Koppen, E., Linke, A., Delagardelle, C., Van Craenenbroeck, E. M., Beckers, P., Prescott, E., Halle, M., Omland, T., Ellingsen, O., Larsen, A. I. & Group, S.-H. S. ESC Heart Fail (2024). https://www.ncbi.nlm.nih.gov/pubmed/38268237
The prevalence and impact of sarcopenia in older cardiac patients undergoing inpatient cardiac rehabilitation - results from a prospective, observational cohort pre-study. Steinmetz, C., Krause, L., Sulejmanovic, S., Kaumkotter, S., Mengden, T., Grefe, C., Knoglinger, E., Reiss, N., Brixius, K., Bjarnason-Wehrens, B., Schmidt, T., von Haehling, S., Sadlonova, M., von Arnim, C. A. F. & Heinemann, S. BMC Geriatr 24, 94 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38267843
C-reactive protein, pharmacological treatments and diet: how to target your inflammatory burden. Bay, B., Arnold, N. & Waldeyer, C. Curr Opin Lipidol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38277208
Transcatheter management of pure native aortic valve regurgitation in patients with left ventricular assist device. Hinkov, H., Lee, C. B., Pitts, L., Lanmuller, P., Klein, C., Kukucka, M., Potapov, E., Kempfert, J., Falk, V., Dreger, H. & Unbehaun, A. Eur J Cardiothorac Surg 65 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38273702
External Mechanical Stability Regulates Hematoma Vascularization in Bone Healing Rather than Endothelial YAP/TAZ Mechanotransduction. Mehl, J., Farahani, S. K., Brauer, E., Klaus-Bergmann, A., Thiele, T., Ellinghaus, A., Bartels-Klein, E., Koch, K., Schmidt-Bleek, K., Petersen, A., Gerhardt, H., Vogel, V. & Duda, G. N. Adv Sci (Weinh) 11, e2307050 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38273642
High-throughput methods for cardiac cellular electrophysiology studies: the road to personalized medicine. Seibertz, F. & Voigt, N. Am J Physiol Heart Circ Physiol 326, H938-H949 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38276947
Noise and mental health: evidence, mechanisms, and consequences. Hahad, O., Kuntic, M., Al-Kindi, S., Kuntic, I., Gilan, D., Petrowski, K., Daiber, A. & Munzel, T. J Expo Sci Environ Epidemiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38279032
Comparison of the clinical chemistry score to other biomarker algorithms for rapid rule-out of acute myocardial infarction and risk stratification in patients with suspected acute coronary syndrome. Yildirim, M., Salbach, C., Reich, C., Milles, B. R., Biener, M., Frey, N., Giannitsis, E. & Mueller-Hennessen, M. Int J Cardiol 400, 131815 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38278492
Risk factors for long-term invasive mechanical ventilation: a longitudinal study using German health claims data. Trudzinski, F. C., Michels-Zetsche, J. D., Neetz, B., Meis, J., Muller, M., Kempa, A., Neurohr, C., Schneider, A., Herth, F. J. F., Szecsenyi, J., Biehler, E., Fleischauer, T., Wensing, M., Britsch, S., Schubert-Haack, J., Grobe, T., Frerk, T. & group, P. R.-s. Respir Res 25, 60 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38281006
Surgical phase and instrument recognition: how to identify appropriate dataset splits. Kostiuchik, G., Sharan, L., Mayer, B., Wolf, I., Preim, B. & Engelhardt, S. Int J Comput Assist Radiol Surg 19, 699-711 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38285380
Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis. Ravindran, A., Holappa, L., Niskanen, H., Skovorodkin, I., Kaisto, S., Beter, M., Kiema, M., Selvarajan, I., Nurminen, V., Aavik, E., Aherrahrou, R., Pasonen-Seppanen, S., Fortino, V., Laakkonen, J. P., Yla-Herttuala, S., Vainio, S., Ord, T. & Kaikkonen, M. U. Cardiovasc Res (2024). https://www.ncbi.nlm.nih.gov/pubmed/38289873
LAA occlusion is effective and safe in very high-risk atrial fibrillation patients with prior stroke: results from the multicentre German LAARGE registry. Ansari, U., Brachmann, J., Lewalter, T., Zeymer, U., Sievert, H., Ledwoch, J., Geist, V., Hochadel, M., Schneider, S., Senges, J., Akin, I. & Fastner, C. Clin Res Cardiol (2024). https://www.ncbi.nlm.nih.gov/pubmed/38294498
Beyond Weight Loss: the Emerging Role of Incretin-Based Treatments in Cardiometabolic HFpEF. Capone, F., Nambiar, N. & Schiattarella, G. G. Curr Opin Cardiol 39, 148-153 (2024). Beyond Weight Loss: the Emerging Role of Incretin-Based Treatments in Cardiometabolic HFpEF - PubMed (nih.gov)
ESR Bridges: CT builds bridges in coronary artery disease. Dewey, M., Henriques, J. P. S., Kirov, H. & Vliegenthart, R. Eur Radiol 34, 732-735 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291257
Cardiac remodelling in non-alcoholic fatty liver disease in the general population. Kostka, F., Ittermann, T., Gross, S., Laqua, F. C., Bulow, R., Volzke, H., Dorr, M., Kuhn, J. P., Markus, M. R. P. & Kromrey, M. L. Liver Int 44, 1032-1041 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38293745
The burden of frailty in heart failure: Prevalence, impacts on clinical outcomes and the role of heart failure medications. Lai, H. Y., Huang, S. T., Anker, S. D., von Haehling, S., Akishita, M., Arai, H., Chen, L. K. & Hsiao, F. Y. J Cachexia Sarcopenia Muscle (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291000
Right heart and left atrial strain to differentiate cardiac amyloidosis and Fabry disease. Mattig, I., Steudel, T., Klingel, K., Barzen, G., Frumkin, D., Spethmann, S., Romero Dorta, E., Stangl, K., Heidecker, B., Landmesser, U., Knebel, F., Canaan-Kuhl, S., Hahn, K. & Brand, A. Sci Rep 14, 2445 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291191
Practical Guide on Left Atrial Appendage Closure for the Non-implanting Physician. An International Consensus Paper. Potpara, T., Grygier, M., Haeusler, K. G., Nielsen-Kudsk, J. E., Berti, S., Genovesi, S., Marijon, E., Boveda, S., Tzikas, A., Boriani, G., Boersma, L. V. A., Tondo, C., De Potter, T., Lip, G. Y. H., Schnabel, R. B., Bauersachs, R., Senzolo, M., Basile, C., Bianchi, S., Osmancik, P., Schmidt, B., Landmesser, U., Doehner, W., Hindricks, G., Kovac, J. & Camm, A. J. Europace (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291925
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Sterenborg, R., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Asvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J., Cappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Coutinho de Almeida, R., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Echouffo Tcheugui, J. B., Ellervik, C., Eriksson, J. G., Ferrucci, L., Freudenberg, J., DiscovEHR, G. H. S., Regeneron Genetics, C., Fuchsberger, C., Gieger, C., Giulianini, F., Gogele, M., Graham, S. E., Grarup, N., Gunjaca, I., Hansen, T., Harding, B. N., Harris, S. E., Haunso, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, J. K., Karhus, L. L., Kiemeney, L., Kloppenburg, M., Kuhnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, A., Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Mollehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polasek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, M. S., Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sorensen, T. I. A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., van den Akker, E. B., van den Eynde, T., van der Klauw, M. M., van Heemst, D., Verroken, C., Visser, W. E., Vojinovic, D., Volzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zollner, S., Smit, J. W. A., Peeters, R. P., Kottgen, A., Teumer, A. & Medici, M. Nat Commun15, 888 (2024). https://www.ncbi.nlm.nih.gov/pubmed/38291025