Paper of the Month

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease, Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators., N Engl J Med. 2016 Mar 2., DZHK-Autoren: Erdmann, König, Franke, Kessler, Laugwitz, Meitinger, Peters, Strauch, Kastrati, Schunkert

Intestinal Congestion and Right Ventricular Dysfunction: A Link with Appetite Loss, Inflammation, and Cachexia in Chronic Heart Failure. Eur Heart J. 2016, DZHK-Autoren: Valentova, von Haehling, Döhner, Ebner, Scherbakov, Anker, Sandek

Foxo1 Couples Metabolic Activity and Growth State in the Vascular Endothelium., Nature (2016), DZHK-Autoren: Braun, Rajewski, Gerhardt, Potente

Critical Role of Rage and Hmgb1 in Inflammatory Heart Disease. Proceedings of the National Academy of Sciences of the United States of America, 2015 Dec 29. pii: 201522288. DZHK-Autoren: Mueller, Katus, Kaya

Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5, Science Translational Medicine 09 Dec 2015: DOI: 10.1126/scitranslmed.aad5330, DZHK-Autoren: Bongiovanni, Horckmans, Paulin, Ng, Hinkel, von Hundelshausen, Steffens, Kupatt, Weber, Soehnlein

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA, Nucleic Acids Research, doi:10.1093/nar/gkv1244, DZHK-Autoren: Cui, Rickert-Sperling

High salt reduces the activation of IL-4– and IL-13–stimulated macrophages. J Clin Invest. 2015. doi:10.1172/JCI80919 | DZHK-Autoren: Hübner, Müller

In vivo model with targeted cAMP biosensor reveals changes in receptor–microdomain communication in cardiac disease, NATURE COMMUNICATIONS | 6:6965, DZHK-Autoren: Lehnart, Hasenfuß, Nikolaev

Sensing Cardiac Electrical Activity with a Cardiomyocyte Targeted Optogenetic Voltage Indicator. Circulation Research. 2015; 117: 401-412, DZHK-Autoren: Chang Liao, Raad, Wagner, Streckfuss-Bömeke, Luther, Guan, Lehnart, Stühmer, Zimmermann

A background Ca21 entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling. European Heart Journal, doi:10.1093/eurheartj/ehv250; DZHK-Autoren: Camacho Londono, Mathar, Freichel