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When the PRDM16 gene mutates, heart muscle cells undergo changes in their metabolism. This increases the risk of congenital heart failure in women more than men, as a ECRC research team led by Sabine Klaassen and Jirko Kühnisch reports in “Cardiovascular Research.”

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A team led by Prof. Wesley Abplanalp at the German Centre for Cardiovascular Research (DZHK) has gained new insights into why so-called CHIP mutations can negatively influence the course of cardiovascular disease. The findings, published in the journal Nature Cardiovascular...

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As part of the Gutenberg Health Study (GHS), researchers from the Department of Cardiology I at the Centre for Cardiology at the Mainz University Hospital and the German Centre for Cardiovascular Research (DZHK) have shown that people with a low socio-economic status have a...

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Many cardiovascular diseases are hereditary. They can now be detected relatively easily, cheaply and quickly using genetic diagnostics. In Germany, however, this technology is only inadequately used. In a consensus paper published by the German Society of Cardiology (DGK), the...

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An international, multi-centre study involving around 2500 patients is investigating the benefits and safety of optical coherence tomography (OCT) as an adjunct to angiography as a laser-based imaging modality for percutaneous coronary intervention (PCI). Prof. Dr. med. Ulf...

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Heart failure is already one of the leading causes of death. It affects around four million people in Germany, and the number is rising. In many cases, heart failure also causes abnormally high blood pressure in the lung vessels. This "pulmonary hypertension" in turn often...

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Heart attacks and strokes are diseases that kill millions of people every year. They are caused by the process of atherosclerosis, also known as arterial calcification. Macrophages play a particularly important role in the development of atherosclerosis in the walls of the blood...

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There has been a sharp increase worldwide in the use of mechanical, active cardiovascular support. The hope is that these devices will improve the chances of survival after the most severe form of acute heart failure, known as cardiogenic shock. A clinical study led by heart...

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Scientists of the Global Cardiovascular Risk Consortium under the auspices of the Department of Cardiology at the University Heart & Vascular Center of the Medical Center Hamburg-Eppendorf (UKE) and the German Center for Cardiovascular Research (DZHK) have proven that the five...

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The clinical trial NOAH – AFNET 6 conducted by the German Atrial Fibrillation Network (AFNET), Münster, Germany, revealed: In patients with atrial high rate episodes (AHRE), but without ECG-documented atrial fibrillation (AF), oral anticoagulation increases bleeding without...

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