Publications 2016

Here you will find publications of the DZHK in chronological order (newest on top). For more publications, please also check out the websites of the individual research institutions that participate in the DZHK.



Clinical Utility of Novel Biomarkers in Acute Myocardial Infarction. Stiermaier, T., Thiele, H. & Eitel, I. Annals of translational medicine 4, 491, (2016).  

Gamma-Glutamyl Transferase and Cardiovascular Disease. Ndrepepa, G. & Kastrati, A. Annals of translational medicine 4, 481, (2016).  

Real-Time Magnetic Resonance Imaging of Deep Venous Flow During Muscular Exercise-Preliminary Experience. Joseph, A. A., Merboldt, K. D., Voit, D., Dahm, J. & Frahm, J. Cardiovascular diagnosis and therapy 6, 473-481, (2016).  

Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice. de Jong, R. J., Paulin, N., Lemnitzer, P., Viola, J. R., Winter, C., Ferraro, B., Grommes, J., Weber, C., Reutelingsperger, C., Drechsler, M. & Soehnlein, O. Arteriosclerosis, thrombosis, and vascular biology, (2016). 

Room for Depressed and Exhausted Mood as a Risk Predictor for All-Cause and Cardiovascular Mortality Beyond the Contribution of the Classical Somatic Risk Factors in Men. Ladwig, K. H., Baumert, J., Marten-Mittag, B., Lukaschek, K., Hamimatunnisa, J., Xioayan, F., Ronel, J., Meisinger, C., Peters, A. & Investigators, f. t. K. Atherosclerosis, (2016). 

Hypertension in Germany. Neuhauser, H., Diederichs, C., Boeing, H., Felix, S. B., Junger, C., Lorbeer, R., Meisinger, C., Peters, A., Volzke, H., Weikert, C., Wild, P. & Dorr, M. Deutsches Arzteblatt international 113, 809-815, (2016). 

Mesenchymal Stromal Cells Modulate Monocytes Trafficking in Coxsackievirus B3-Induced Myocarditis. Miteva, K., Pappritz, K., El-Shafeey, M., Dong, F., Ringe, J., Tschöpe, C. & Van Linthout, S. Stem cells translational medicine, (2016).

High-Sensitivity Cardiac Troponin I and Nt-Probnp as Predictors of Incident Dementia and Alzheimer's Disease: The Finrisk Study. Tynkkynen, J., Hernesniemi, J. A., Laatikainen, T., Havulinna, A. S., Salo, P., Blankenberg, S., Zeller, T. & Salomaa, V. Journal of neurology, (2016).  

Cross-Talk between Lipid and Protein Carbonylation in a Dynamic Cardiomyocyte Model of Mild Nitroxidative Stress. Griesser, E., Vemula, V., Raulien, N., Wagner, U., Reeg, S., Grune, T. & Fedorova, M. Redox biology, (2016).  

First Evidence of Complete Resorption 4 Years after Bioresorbable Scaffold Implantation in the Setting of St-Segment Elevation Myocardial Infarction. Gori, T. & Munzel, T. JACC. Cardiovascular interventions, (2016).  

Challenging the 99th Percentile: A Lower Troponin Cutoff Leads to Low Mortality of Chest Pain Patients. Sörensen, N. A., Neumann, J. T., Ojeda, F., Schwemer, T., Renne, T., Schnabel, R. B., Zeller, T., Karakas, M., Blankenberg, S. & Westermann, D. International journal of cardiology, (2016).  

Quality of Life after Transcatheter Aortic Valve Replacement: Prospective Data from Gary (German Aortic Valve Registry). Lange, R., Beckmann, A., Neumann, T., Krane, M., Deutsch, M. A., Landwehr, S., Kotting, J., Welz, A., Zahn, R., Cremer, J., Figulla, H. R., Schuler, G., Holzhey, D. M., Funkat, A. K., Heusch, G., Sack, S., Pasic, M., Meinertz, T., Walther, T., Kuck, K. H. et al. JACC. Cardiovascular interventions 9, 2541-2554, (2016).  

Mirnas in Ancient Tissue Specimens of the Tyrolean Iceman. Keller, A., Kreis, S., Leidinger, P., Maixner, F., Ludwig, N., Backes, C., Galata, V., Guerriero, G., Fehlmann, T., Franke, A., Meder, B., Zink, A. & Meese, E. Molecular biology and evolution, (2016).  

Results of Mitral Valve Repair with an Adjustable Annuloplasty Ring 2 Years after Implantation. Sundermann, S. H., Czesla, M., Kempfert, J., Walther, T., Nataf, P., Raanani, E., Jacobs, S., Alfieri, O., Maisano, F. & Falk, V. Heart and vessels, (2016).  

Profiling and Validation of Circulating Micrornas for Cardiovascular Events in Patients Presenting with St-Segment Elevation Myocardial Infarction. Jakob, P., Kacprowski, T., Briand-Schumacher, S., Heg, D., Klingenberg, R., Stahli, B. E., Jaguszewski, M., Rodondi, N., Nanchen, D., Raber, L., Vogt, P., Mach, F., Windecker, S., Volker, U., Matter, C. M., Luscher, T. F. & Landmesser, U. European heart journal, (2016).  

Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction: A Plea for Proper Phenotyping and Further Researchdagger. Hoeper, M. M., Lam, C. S., Vachiery, J. L., Bauersachs, J., Gerges, C., Lang, I. M., Bonderman, D., Olsson, K. M., Gibbs, J. S., Dorfmuller, P., Guazzi, M., Galie, N., Manes, A., Handoko, M. L., Vonk-Noordegraaf, A., Lankeit, M., Konstantinides, S., Wachter, R., Opitz, C. & Rosenkranz, S. European heart journal, (2016).  

Knock out of the Nadph Oxidase Nox4 Has No Impact on Life Span in Mice. Rezende, F., Schurmann, C., Schutz, S., Harenkamp, S., Herrmann, E., Seimetz, M., Weissmann, N. & Schroder, K. Redox biology 11, 312-314, (2016).  

Optical Coherence Tomography to Evaluate Plaque Burden and Morphology in Patients with Takotsubo Syndrome. Eitel, I., Stiermaier, T., Graf, T., Moller, C., Rommel, K. P., Eitel, C., Schuler, G., Thiele, H. & Desch, S. Journal of the American Heart Association 5, (2016).  

Epigenome-Wide Association Study of Body Mass Index, and the Adverse Outcomes of Adiposity. Wahl, S., Drong, A., Lehne, B., Loh, M., Scott, W. R., Kunze, S., Tsai, P. C., Ried, J. S., Zhang, W., Yang, Y., Tan, S., Fiorito, G., Franke, L., Guarrera, S., Kasela, S., Kriebel, J., Richmond, R. C., Adamo, M., Afzal, U., Ala-Korpela, M. et al. Nature, (2016).  

Biventricular Endomyocardial Biopsy in Patients with Suspected Myocarditis: Feasibility, Complication Rate and Additional Diagnostic Value. Stiermaier, T., Fohrenbach, F., Klingel, K., Kandolf, R., Boudriot, E., Sandri, M., Linke, A., Rommel, K. P., Desch, S., Schuler, G., Thiele, H. & Lurz, P. International journal of cardiology, (2016).  

Midregional Proadrenomedullin and Growth Differentiation Factor-15 Are Not Influenced by Obesity in Heart Failure Patients. Sinning, C., Ojeda, F., Wild, P. S., Schnabel, R. B., Schwarzl, M., Ohdah, S., Lackner, K. J., Pfeiffer, N., Michal, M., Blettner, M., Munzel, T., Kempf, T., Wollert, K. C., Kuulasmaa, K., Blankenberg, S., Salomaa, V., Westermann, D. & Zeller, T. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).  

Regionale Unterschiede in Der Prävalenz Von Kardiovaskulären Risikofaktoren Bei Männern Und Frauen in Deutschland. Diederichs, C., Neuhauser, H., Kroll, L., Lange, C., Mensink, G., Dornquast, C., Heidemann, C., Scheidt-Nave, C. & Busch, M. Bundesgesundheitsbl. .  

Association of Atopic Dermatitis with Cardiovascular Risk Factors and Diseases. Standl, M., Tesch, F., Baurecht, H., Rodriguez, E., Muller-Nurasyid, M., Gieger, C., Peters, A., Wang-Sattler, R., Prehn, C., Adamski, J., Kronenberg, F., Schulz, H., Koletzko, S., Schikowski, T., von Berg, A., Lehmann, I., Berdel, D., Heinrich, J., Schmitt, J. & Weidinger, S. The Journal of investigative dermatology, (2016).  

Letter by El-Battrawy Et Al Regarding Article, "Takotsubo-Like Myocardial Dysfunction in Ischemic Stroke: A Hospital-Based Registry and Systematic Literature Review". El-Battrawy, I., Borggrefe, M. & Akin, I. Stroke; a journal of cerebral circulation, (2016).  

Response by Crotti Et Al to Letter Regarding Article, “Genetic Modifiers for the Long-Qt Syndrome: How Important Is the Role of Variants in the 3′ Untranslated Region of Kcnq1?”. Crotti, L., Lahtinen, A. M., Spazzolini, C., Mastantuono, E., Monti, M. C., Morassutto, C., Parati, G., Heradien, M., Goosen, A., Lichtner, P., Meitinger, T., Brink, P. A., Kontula, K., Swan, H. & Schwartz, P. J. Circulation: Cardiovascular Genetics, (2016).  

Genome-Wide Trans-Ethnic Meta-Analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for Rbpms in Erythropoiesis. van Rooij, F. J., Qayyum, R., Smith, A. V., Zhou, Y., Trompet, S., Tanaka, T., Keller, M. F., Chang, L. C., Schmidt, H., Yang, M. L., Chen, M. H., Hayes, J., Johnson, A. D., Yanek, L. R., Mueller, C., Lange, L., Floyd, J. S., Ghanbari, M., Zonderman, A. B., Jukema, J. W. et al. American journal of human genetics, (2016).  

Cardiac Computed Tomography : A New Player in the Imaging Portfolio for Myocardial Fibrosis. Noutsias, M., Mavrogeni, S., Spillmann, F. & Tschope, C. Herz, (2016).  

An Exploratory Propensity-Score Matched Comparison of Second-Generation and First-Generation Baroreflex Activation Therapy Systems. Wachter, R., Halbach, M., Bakris, G. L., Bisognano, J. D., Haller, H., Beige, J., Kroon, A. A., Nadim, M. K., Lovett, E. G., Schafer, J. E. & De Leeuw, P. W. J Am Soc Hypertens, (2016).  

Malondialdehyde Epitopes Are Sterile Mediators of Hepatic Inflammation in Hypercholesterolemic Mice. Busch, C. J., Hendrikx, T., Weismann, D., Jackel, S., Walenbergh, S. M., Rendeiro, A. F., Weisser, J., Puhm, F., Hladik, A., Goderle, L., Papac-Milicevic, N., Haas, G., Millischer, V., Subramaniam, S., Knapp, S., Bennett, K. L., Bock, C., Reinhardt, C., Shiri-Sverdlov, R. & Binder, C. J. Hepatology, (2016).  

The Link between Angiogenesis and Endothelial Metabolism. Potente, M. & Carmeliet, P. Annu Rev Physiol, (2016).  

Targeting Loxl2 for Cardiac Interstitial Fibrosis and Heart Failure Treatment. Yang, J., Savvatis, K., Kang, J. S., Fan, P., Zhong, H., Schwartz, K., Barry, V., Mikels-Vigdal, A., Karpinski, S., Kornyeyev, D., Adamkewicz, J., Feng, X., Zhou, Q., Shang, C., Kumar, P., Phan, D., Kasner, M., Lopez, B., Diez, J., Wright, K. C. et al. Nature communications 7, 13710, (2016).  

Metabolic Profiling of Pregnancy: Cross-Sectional and Longitudinal Evidence. Wang, Q., Wurtz, P., Auro, K., Makinen, V. P., Kangas, A. J., Soininen, P., Tiainen, M., Tynkkynen, T., Jokelainen, J., Santalahti, K., Salmi, M., Blankenberg, S., Zeller, T., Viikari, J., Kahonen, M., Lehtimaki, T., Salomaa, V., Perola, M., Jalkanen, S., Jarvelin, M. R. et al. BMC Med 14, 205, (2016).  

Transcatheter Edge-to-Edge Mitral Valve Repair in Heart Failure. Orban, M., Orban, M., Braun, D., Nabauer, M., Massberg, S. & Hausleiter, J. Minerva cardioangiologica, (2016).  

DNA Methylation Signatures of Chronic Low-Grade Inflammation Are Associated with Complex Diseases. Ligthart, S., Marzi, C., Aslibekyan, S., Mendelson, M. M., Conneely, K. N., Tanaka, T., Colicino, E., Waite, L. L., Joehanes, R., Guan, W., Brody, J. A., Elks, C., Marioni, R., Jhun, M. A., Agha, G., Bressler, J., Ward-Caviness, C. K., Chen, B. H., Huan, T., Bakulski, K. et al. Genome biology 17, 255, (2016).  

Mberhappily (N)Ever After: Aging in the Context of Oxidative Stress, Proteostasis Loss and Cellular Senescence. Höhn, A., Weber, D., Jung, T., Ott, C., Hugo, M., Kochlik, B., Kehm, R., König, J., Grune, T. & Pedro Castro, J. Redox biology, (2016).  

Gamma-Glutamyl Transferase and Atrial Fibrillation in Patients with Coronary Artery Disease. Ndrepepa, G., Xhepa, E., Colleran, R., Braun, S., Cassese, S., Fusaro, M., Laugwitz, K. L. & Kastrati, A. Clinica chimica acta; international journal of clinical chemistry 465, 17-21, (2016).  

Reply To: Diabetes Mellitus and Takotsubo Syndrome: Dissecting the Paradox. El-Battrawy, I., Bill, V., Borggrefe, M. & Akin, I. International journal of cardiology, (2016).  

Epigallocatechin-3-Gallate Accelerates Relaxation and Ca2+ Transient Decay and Desensitizes Myofilaments in Healthy and Mybpc3-Targeted Knock-in Cardiomyopathic Mice. Friedrich, F. W., Flenner, F., Nasib, M., Eschenhagen, T. & Carrier, L. Frontiers in physiology 7, 607, (2016).  

Optimal Periprocedural Antithrombotic Therapy in Percutaneous Coronary Intervention: Between a Rock and a Hard Place? Giacoppo, D. & Kastrati, A. Cardiovasc Revasc Med, (2016).  

Pooling and Expanding Registries of Familial Hypercholesterolaemia to Assess Gaps in Care and Improve Disease Management and Outcomes: Rationale and Design of the Global Eas Familial Hypercholesterolaemia Studies Collaboration. Collaboration, E. A. S. F. H. S., Vallejo-Vaz, A. J., Akram, A., Kondapally Seshasai, S. R., Cole, D., Watts, G. F., Hovingh, G. K., Kastelein, J. J., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Freiberger, T., Abifadel, M., Aguilar-Salinas, C. A., Alnouri, F., Alonso, R., Al-Rasadi, K., Banach, M., Bogsrud, M. P. et al. Atherosclerosis. Supplements 22, 1-32, (2016).  

Impact of the Mica-129met/Val Dimorphism on Nkg2d-Mediated Biological Functions and Disease Risks. Isernhagen, A., Malzahn, D., Bickeböller, H. & Dressel, R. Frontiers in immunology, (2016).  

Epigenetics and Control of Rnas. Maatz, H., van Heesch, S., Kreuchwig, F., Faber, A., Adami, E., Hubner, N. & Heinig, M. Methods in molecular biology 1488, 217-237, (2017).  

Interactions of Calcium Fluctuations During Cardiomyocyte Contraction with Real-Time Camp Dynamics Detected by Fret. Sprenger, J. U., Bork, N. I., Herting, J., Fischer, T. H. & Nikolaev, V. O. PloS one 11, e0167974, (2016).  

Postprocedural Radial Artery Occlusion Rate Using a Sheathless Guiding Catheter for Left Ventricular Endomyocardial Biopsy Performed by Transradial Approach. Kherad, B., Kohncke, C., Spillmann, F., Post, H., Noutsias, M., Pieske, B., Krackhardt, F. & Tschope, C. BMC cardiovascular disorders 16, 253, (2016).  

Incidence, Laboratory Detection and Prognostic Relevance of Hypoxic Hepatitis in Cardiogenic Shock. Jung, C., Fuernau, G., Eitel, I., Desch, S., Schuler, G., Kelm, M., Adams, V. & Thiele, H. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).  

Nucleoside Diphosphate Kinase-C Suppresses Camp Formation in Human Heart Failure. Abu-Taha, I. H., Heijman, J., Hippe, H. J., Wolf, N. M., El-Armouche, A., Nikolaev, V. O., Schafer, M., Wurtz, C., Neef, S., Voigt, N., Baczko, I., Varro, A., Muller, M., Meder, B., Katus, H. A., Spiger, K., Vettel, C., Lehmann, L. H., Backs, J., Skolnik, E. Y. et al. Circulation, (2016).  

Pim1 Overexpressing Ckit+ Cardiac Stem Cells in Cardiac Regeneration: Preconditioning as Next-Generation Stem Cell Therapy? Hinkel, R. Journal of the American College of Cardiology 68, 2465-2466, (2016).  

Multiethnic Genome-Wide Meta-Analysis of Ectopic Fat Depots Identifies Loci Associated with Adipocyte Development and Differentiation. Chu, A. Y., Deng, X., Fisher, V. A., Drong, A., Zhang, Y., Feitosa, M. F., Liu, C. T., Weeks, O., Choh, A. C., Duan, Q., Dyer, T. D., Eicher, J. D., Guo, X., Heard-Costa, N. L., Kacprowski, T., Kent, J. W., Jr., Lange, L. A., Liu, X., Lohman, K., Lu, L. et al. Nature genetics, (2016).  

Hypoxia Inducible Factor Stabilization Improves Defective Ischemia-Induced Angiogenesis in a Rodent Model of Chronic Kidney Disease. Schellinger, I. N., Cordasic, N., Panesar, J., Buchholz, B., Jacobi, J., Hartner, A., Klanke, B., Jakubiczka-Smorag, J., Burzlaff, N., Heinze, E., Warnecke, C., Raaz, U., Willam, C., Tsao, P. S., Eckardt, K. U., Amann, K. & Hilgers, K. F. Kidney international, (2016).  

Micrornas in Cardiovascular Disease - Clinical Application. Schulte, C., Karakas, M. & Zeller, T. Clinical chemistry and laboratory medicine, (2016).  

Systematic Ajmaline Challenge in Patients with Long Qt 3 Syndrome Caused by the Most Common Mutation: A Multicentre Study. Hohmann, S., Rudic, B., Konrad, T., Duncker, D., Konig, T., Tulumen, E., Rostock, T., Borggrefe, M. & Veltmann, C. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).  

Selective Pressure-Regulated Retroinfusion for Gene Therapy Application in Ischemic Heart Disease. Hinkel, R. & Kupatt, C. Methods in molecular biology 1521, 249-260, (2017).  

Epigenetic Control of Microsomal Prostaglandin E Synthase-1 by Hdac Mediated Recruitment of P300. Fork, C., Vasconez, A. E., Janetzko, P., Angioni, C., Schreiber, Y., Ferreiros, N., Geisslinger, G., Leisegang, M. S., Steinhilber, D. & Brandes, R. P. Journal of lipid research, (2016).  

A Laboratory Critical Incident and Error Reporting System for Experimental Biomedicine. Dirnagl, U., Przesdzing, I., Kurreck, C. & Major, S. PLoS biology 14, e2000705, (2016).  

Interventional Therapies in Acute Myocardial Infarction Complicated by Cardiogenic Shock. de Waha, S., Desch, S., Fuernau, G., Poss, J., Ledwoch, J., Jobs, A., Eitel, I. & Thiele, H. Herz, (2016).  

Rapid Functional Cardiac Imaging after Gadolinium Injection: Evaluation of a Highly Accelerated Sequence with Sparse Data Sampling and Iterative Reconstruction. Budjan, J., Haubenreisser, H., Henzler, T., Sudarski, S., Schmidt, M., Doesch, C., Akin, I., Borggrefe, M., Messner, N. M., Schoenberg, S. O., Attenberger, U. I. & Papavassiliu, T. Scientific reports 6, 38236, (2016).  

Exercise Training Improves Exercise Capacity and Quality of Life after Transcatheter Aortic Valve Implantation: A Randomized Pilot Trial. Pressler, A., Christle, J. W., Lechner, B., Grabs, V., Haller, B., Hettich, I., Jochheim, D., Mehilli, J., Lange, R., Bleiziffer, S. & Halle, M. American heart journal 182, 44-53, (2016).  



MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions. Eken, S. M., Jin, H., Chernogubova, E., Li, Y., Simon, N., Sun, C., Korzunowicz, G., Busch, A., Backlund, A., Osterholm, C., Razuvaev, A., Renne, T., Eckstein, H. H., Pelisek, J., Eriksson, P., Gonzalez Diez, M., Matic Perisic, L. P., Schellinger, I. N., Raaz, U., Leeper, N. J., Hansson, G. K., Paulsson-Berne, G., Hedin, U. & Maegdefessel, L. Circulation Research (2016).

Oral Thrombin Inhibitor Aggravates Platelet Adhesion and Aggregation During Arterial Thrombosis. Petzold, T., Thienel, M., Konrad, I., Schubert, I., Regenauer, R., Hoppe, B., Lorenz, M., Eckart, A., Chandraratne, S., Lennerz, C., Kolb, C., Braun, D., Jamasbi, J., Brandl, R., Braun, S., Siess, W., Schulz, C. & Massberg, S. Science translational medicine, (2016).  

High-Sensitivity Troponin T and Mortality after Elective Percutaneous Coronary Intervention. Ndrepepa, G., Colleran, R., Braun, S., Cassese, S., Hieber, J., Fusaro, M., Kufner, S., Ott, I., Byrne, R. A., Husser, O., Hengstenberg, C., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Journal of the American College of Cardiology 68, 2259-2268, (2016).  

Repression of Telomere-Associated Genes by Microglia Activation in Neuropsychiatric Disease. Kronenberg, G., Uhlemann, R., Schoner, J., Wegner, S., Boujon, V., Deigendesch, N., Endres, M. & Gertz, K. European archives of psychiatry and clinical neuroscience, (2016).  

Circulating Angiopoietin-2 and Its Soluble Receptor Tie-2 Concentrations Are Related to Renal Function in Two Population-Based Cohorts. Hennings, A., Hannemann, A., Rettig, R., Dorr, M., Nauck, M., Volzke, H., Lerch, M. M., Lieb, W. & Friedrich, N. PloS one 11, e0166492, (2016).  

Impact of Clinical Presentation on Early Vascular Healing after Bioresorbable Vascular Scaffold Implantation. Baquet, M., Brenner, C., Wenzler, M., Eickhoff, M., David, J., Brunner, S., Theiss, H., Massberg, S., Guagliumi, G. & Mehilli, J. Journal of interventional cardiology, (2016).  

Reducing Rbm20 Activity Improves Diastolic Dysfunction and Cardiac Atrophy. Hinze, F., Dieterich, C., Radke, M. H., Granzier, H. & Gotthardt, M. Journal of molecular medicine, (2016).  

Strategies to Overcome Misdiagnosis of Type 1 Myocardial Infarction Using High Sensitive Cardiac Troponin Assays von Jeinsen, B. & Keller, T. Diagnosis 3, 189-198, (2016).  

T2-Weighted Cardiovascular Magnetic Resonance Imaging to Delineate Ischemic Myocardium at Risk: Fact or Fiction? Stiermaier, T., Thiele, H. & Eitel, I. Revista espanola de cardiologia, (2016).  

Metabolic Health in Relation to Body Size: Changes in Prevalence over Time between 1997-99 and 2008-11 in Germany. Truthmann, J., Mensink, G. B., Bosy-Westphal, A., Scheidt-Nave, C. & Schienkiewitz, A. PloS one 11, e0167159, (2016).  

A Principal Component Meta-Analysis on Multiple Anthropometric Traits Identifies Novel Loci for Body Shape. Ried, J. S., Jeff, M. J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. et al. Nature communications 7, 13357, (2016).  

Apixaban for Treatment of Embolic Stroke of Undetermined Source (Atticus Randomized Trial): Rationale and Study Design. Geisler, T., Poli, S., Meisner, C., Schreieck, J., Zuern, C. S., Nagele, T., Brachmann, J., Jung, W., Gahn, G., Schmid, E., Baezner, H., Keller, T., Petzold, G. C., Schrickel, J. W., Liman, J., Wachter, R., Schon, F., Schabet, M., Lindner, A., Ludolph, A. C. et al. International journal of stroke : official journal of the International Stroke Society, (2016).  

The Influence of Sex on Microvascular Function. Orphal, D. & Gori, T. Clin Hemorh Microcirc, (2016).  

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dorr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S. J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikainen, L. P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., Smith, A. V. et al. Circulation. Cardiovascular genetics, (2016).  


Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation. Biermann, D., Eder, A., Arndt, F., Seoudy, H., Reichenspurner, H., Mir, T., Riso, A., Kozlik-Feldmann, R., Peldschus, K., Kaul, M. G., Schuler, T., Krasemann, S., Hansen, A., Eschenhagen, T. & Sachweh, J. S. PloS one 11, e0166963, (2016).  

Titin-Truncating Variants Affect Heart Function in Disease Cohorts and the General Population. Schafer, S., de Marvao, A., Adami, E., Fiedler, L. R., Ng, B., Khin, E., Rackham, O. J., van Heesch, S., Pua, C. J., Kui, M., Walsh, R., Tayal, U., Prasad, S. K., Dawes, T. J., Ko, N. S., Sim, D., Chan, L. L., Chin, C. W., Mazzarotto, F., Barton, P. J. et al. Nature genetics, (2016).  

Myocardial T1-Mapping at 3t Using Saturation-Recovery: Reference Values, Precision and Comparison with Molli. Weingartner, S., Messner, N. M., Budjan, J., Lossnitzer, D., Mattler, U., Papavassiliu, T., Zollner, F. G. & Schad, L. R. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 18, 84, (2016).  

Cisplatin-Related Cerebral Infarction in Testicular Germ Cell Cancer: Short Report of Three Cases and Pathomechanism. Lange, J., Audebert, H. J., Endres, M. & Rocco, A. Clin Neurol Neurosurg, (2016).  

Endothelial Dysfunction in Takotsubo Syndrome. El-Battrawy, I., Borggrefe, M. & Akin, I. International journal of cardiology, (2016).  

The Advantageous Role of Annexin A1 in Cardiovascular Disease. de Jong, R. J., Leoni, G., Drechsler, M. & Soehnlein, O. Cell adhesion & migration, 0, (2016).  

The New Esc Guidelines for Acute and Chronic Heart Failure 2016. Oeing, C. U., Tschöpe, C. & Pieske, B. Herz, (2016).  

Finding Ms. Or Mr. Right: Which Mirna to Target in Af? Molina, C. E. & Voigt, N. Journal of molecular and cellular cardiology, (2016).  

Implantation of a Mitraclip between Two Previously Implanted Mitraclips to Treat Recurrent Severe Mitral Regurgitation. Lesevic, H., Sonne, C., Kasel, A. M., Breuer, D., Kastrati, A., Schunkert, H. & Ott, I. J Cardiol Cases, (2016).  

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A DNA Methylation Biomarker of Alcohol Consumption. Liu, C., Marioni, R. E., Hedman, A. K., Pfeiffer, L., Tsai, P. C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kuhnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C. et al. Molecular psychiatry, (2016).  

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The Incidence of Hypertension and Its Risk Factors in the German Adult Population: Results from the German National Health Interview and Examination Survey 1998 and the German Health Interview and Examination Survey for Adults 2008-2011. Diederichs, C. & Neuhauser, H. Journal of hypertension, (2016).  

Intralipid Protects the Heart in Late Pregnancy against Ischemia/Reperfusion Injury Via Caveolin2/Stat3/Gsk-3beta Pathway. Li, J., Ruffenach, G., Kararigas, G., Cunningham, C. M., Motayagheni, N., Barakai, N., Umar, S., Regitz-Zagrosek, V. & Eghbali, M. Journal of molecular and cellular cardiology, (2016).  

Antecedent Hypertension and Myocardial Injury in Patients with Reperfused St-Elevation Myocardial Infarction. Reinstadler, S. J., Stiermaier, T., Eitel, C., Saad, M., Metzler, B., de Waha, S., Fuernau, G., Desch, S., Thiele, H. & Eitel, I. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 18, 80, (2016).  

Comprehensive Endovascular Treatment of Multiple Arterial Emboli Involving Lima Graft, Distal Aorta and Upper and Lower Extremities in a Patient with Subacute Cerebral Hemorrhage. Langwieser, N., Laugwitz, K. L. & Ibrahim, T. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).  

Biomarkers for Characterization of Heart Failure - Distinction of Heart Failure with Preserved and Reduced Ejection Fraction. Sinning, C., Kempf, T., Schwarzl, M., Lanfermann, S., Ojeda, F., Schnabel, R. B., Zengin, E., Wild, P. S., Lackner, K. J., Munzel, T., Blankenberg, S., Wollert, K. C., Zeller, T. & Westermann, D. International journal of cardiology, (2016).  

Catalytic Iron in Acute Myocardial Infarction Complicated by Cardiogenic Shock — a Biomarker Substudy of the Iabp-Shock Ii-Trial. Fuernau, G., Traeder, F., Lele, S. S., M.M., R., Mukhopadhyay, B., de Waha, S., Desch, S., Eitel, I., Schuler, G., Adams, V. & Thiele, H. International journal of cardiology, (2016).  

Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. El-Battrawy, I., Lang, S., Zhao, Z., Akin, I., Yucel, G., Meister, S., Patocskai, B., Behnes, M., Rudic, B., Tulumen, E., Liebe, V., Tiburcy, M., Dworacek, J., Zimmermann, W. H., Utikal, J., Wieland, T., Borggrefe, M. & Zhou, X. B. PloS one 11, e0166143, (2016).  

Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles. Qin, X., Riegler, J., Tiburcy, M., Zhao, X., Chour, T., Ndoye, B., Nguyen, M., Adams, J., Ameen, M., Denney, T. S., Yang, P. C., Nguyen, P., Zimmermann, W. H. & Wu, J. C. Circulation. Cardiovascular imaging, (2016).  

Epigenetic Signatures at Aqp3 and Socs3 Engage in Low-Grade Inflammation across Different Tissues. Marzi, C., Holdt, L. M., Fiorito, G., Tsai, P. C., Kretschmer, A., Wahl, S., Guarrera, S., Teupser, D., Spector, T. D., Iacoviello, L., Sacerdote, C., Strauch, K., Lee, S., Thasler, W. E., Peters, A., Thorand, B., Wolf, P., Prokisch, H., Tumino, R., Gieger, C. et al. PloS one 11, e0166015, (2016).  

Gene-Gene Interaction Analyses for Atrial Fibrillation. Lin, H., Mueller-Nurasyid, M., Smith, A. V., Arking, D. E., Barnard, J., Bartz, T. M., Lunetta, K. L., Lohman, K., Kleber, M. E., Lubitz, S. A., Geelhoed, B., Trompet, S., Niemeijer, M. N., Kacprowski, T., Chasman, D. I., Klarin, D., Sinner, M. F., Waldenberger, M., Meitinger, T., Harris, T. B. et al. Scientific reports 6, 35371, (2016).  

Cmr First-Pass Perfusion for Suspected Inducible Myocardial Ischemia. Hendel, R. C., Friedrich, M. G., Schulz-Menger, J., Zemmrich, C., Bengel, F., Berman, D. S., Camici, P. G., Flamm, S. D., Le Guludec, D., Kim, R., Lombardi, M., Mahmarian, J., Sechtem, U. & Nagel, E. JACC. Cardiovascular imaging 9, 1338-1348, (2016).  

Factors Associated with Fatal Outcome in Posterior Reversible Encephalopathy Syndrome: A Retrospective Analysis of the Berlin Pres Study. Siebert, E., Bohner, G., Liebig, T., Endres, M. & Liman, T. G. Journal of neurology, (2016).  

Response to Prof. Dr. Med. Gunther Wiesner, Prof. Dr. Med. Peter Tassani-Prell, and Dr. Patrick Mayr : Deep Sedation Versus General Anaesthesia in Percutaneous Edge-to-Edge Mitral Valve Reconstruction Using the Mitraclip System. de Waha, S., Desch, S., Eitel, I. & Thiele, H. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).  

Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice. Brachs, S., Winkel, A. F., Polack, J., Tang, H., Brachs, M., Margerie, D., Brunner, B., Jahn-Hoffmann, K., Ruetten, H., Spranger, J. & Schmoll, D. PloS one.  

Growth Differentiation Factor 15 Predicts All-Cause Morbidity and Mortality in Stable Coronary Heart Disease. Hagstrom, E., Held, C., Stewart, R. A., Aylward, P. E., Budaj, A., Cannon, C. P., Koenig, W., Krug-Gourley, S., Mohler, E. R., 3rd, Steg, P. G., Tarka, E., Ostlund, O., White, H. D., Siegbahn, A., Wallentin, L. & Investigators, S. Clinical chemistry, (2016).  

Cardiac Repair in Guinea Pigs with Human Engineered Heart Tissue from Induced Pluripotent Stem Cells. Weinberger, F., Breckwoldt, K., Pecha, S., Kelly, A., Geertz, B., Starbatty, J., Yorgan, T., Cheng, K. H., Lessmann, K., Stolen, T., Scherrer-Crosbie, M., Smith, G., Reichenspurner, H., Hansen, A. & Eschenhagen, T. Science translational medicine 8, 363ra148, (2016).  

Mechanistic Pathways of Sex Differences in Cardiovascular Disease. Regitz-Zagrosek, V. & Kararigas, G. Physiological reviews 97, 1-37, (2017).  

Mir-19b Regulates Ventricular Action Potential Duration in Zebrafish. Benz, A., Kossack, M., Auth, D., Seyler, C., Zitron, E., Juergensen, L., Katus, H. A. & Hassel, D. Scientific reports 6, 36033, (2016).  

Influence of Roi Definition on the Heart-to-Mediastinum Ratio in Planar 123i-Mibg Imaging. Klene, C., Jungen, C., Okuda, K., Kobayashi, Y., Helberg, A., Mester, J., Meyer, C. & Nakajima, K. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, (2016).  

Clinical Outcomes of Femoral Closure Compared to Radial Compression Devices Following Percutaneous Coronary Intervention: The Ferari Study. Fastner, C., Behnes, M., Unsal, M., El-Battrawy, I., Ansari, U., Mashayekhi, K., Hoffmann, U., Lang, S., Kuschyk, J., Borggrefe, M. & Akin, I. Heart and vessels, (2016).  

4-Hydroxynonenal (Hne) Modified Proteins in Metabolic Diseases. Castro, J. P., Grune, T. & Siems, W. Free radical biology & medicine, (2016).  

The Veleti Ii Trial (Sealing Moderate Coronary Saphenous Vein Graft Lesions with Paclitaxel-Eluting Stents): Local Mechanical Intervention Fails to Stop Atheroprogression in Saphenous Vein Grafts. Mehilli, J. Circulation. Cardiovascular interventions 9, (2016).  

Cmr First-Pass Perfusion for Suspected Inducible Myocardial Ischemia. Hendel, R. C., Friedrich, M. G., Schulz-Menger, J., Zemmrich, C., Bengel, F., Berman, D. S., Camici, B. G., Flamm, S. D., Le Guludec, D., Kim, R., Lombardi, M., Mahmarian, J., Sechtem, U. & Nagel, E. JACC. Cardiovascular imaging 9, 1338-1348, (2016).  

Clinical Evaluation of Three-Dimensional Late Enhancement Mri. Bratis, K., Henningsson, M., Grigoratos, C., Omodarme, M. D., Chasapides, K., Botnar, R. & Nagel, E. Journal of magnetic resonance imaging : JMRI, (2016).  

Reply to the Editor- Implantation of Permanent Devices in Patients with Takotsubo Syndrome. Stiermaier, T., Thiele, H. & Eitel, I. Heart rhythm : the official journal of the Heart Rhythm Society 13, e329, (2016).  

Inducible Cardiomyocyte-Specific Deletion of Cam Kinase Ii Protects from Pressure Overload-Induced Heart Failure. Kreusser, M. M., Lehmann, L. H., Wolf, N., Keranov, S., Jungmann, A., Grone, H. J., Muller, O. J., Katus, H. A. & Backs, J. Basic research in cardiology 111, 65, (2016).  

Inhibition of Cardiac Camkii to Cure Heart Failure: Step by Step Towards Translation? Cuello, F. & Lorenz, K. Basic research in cardiology 111, 66, (2016).



Immediate Rule-out of Acute Myocardial Infarction Using Electrocardiogram and Baseline High-Sensitivity Troponin I. Neumann, J. T., Sorensen, N. A., Ojeda, F., Schwemer, T., Lehmacher, J., Gonner, S., Jarsetz, N., Keller, T., Schaefer, S., Renne, T., Landmesser, U., Clemmensen, P., Makarova, N., Schnabel, R. B., Zeller, T., Karakas, M., Pickering, J. W., Than, M., Parsonage, W., Greenslade, J. et al. Clinical chemistry, (2016).  

Pcsk9 Genetic Variants and Risk of Type 2 Diabetes: A Mendelian Randomisation Study. Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., van Iperen, E., Hovingh, G. K., Demuth, I., Norman, K., Steinhagen-Thiessen, E., Demuth, J., Bertram, L., Liu, T., Coassin, S. et al. The lancet. Diabetes & endocrinology, (2016).  

Micro RNA Assays for Acute Coronary Syndromes. Samani, O. S. & Meder, B. Diagnosis, (2016).

Antiplatelet Therapies in Patients with an Indication for Anticoagulation. Ullrich, H. & Gori, T. Clin Hemorh Microcirc, (2016).  

Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis. von Scheidt, M., Zhao, Y., Kurt, Z., Pan, C., Zeng, L., Yang, X., Schunkert, H. & Lusis, A. J. Cell metabolism, (2016).  

Simultaneous Non-Invasive Epicardial and Endocardial Mapping in Patients with Brugada Syndrome: New Insights into Arrhythmia Mechanisms. Rudic, B., Chaykovskaya, M., Tsyganov, A., Kalinin, V., Tülümen, E., Papavassiliu, T., Dösch, C., Liebe, V., Kuschyk, J., Röger, S., El-Battrawy, I., Akin, I., Yakovleva, M., Zaklyazminskaya, E., Shestak, A., Kim, S., Chmelevsky, M. & Borggrefe, M. Journal of the American Heart Association, (2016).  

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Regional Differences in the Prevalence of Cardiovascular Disease. Dornquast, C., Kroll, L. E., Neuhauser, H. K., Willich, S. N., Reinhold, T. & Busch, M. A. Deutsches Arzteblatt international 113, 704-711, (2016).  

Ventricular Function and Ventriculo-Arterial Coupling after Palliation of Hypoplastic Left Heart Syndrome: A Comparative Study with Fontan Patients with Lv Morphology. Logoteta, J., Ruppel, C., Hansen, J. H., Fischer, G., Becker, K., Kramer, H. H. & Uebing, A. International journal of cardiology, (2016).  

Disappearing Scaffolds, Dissolving Expectations. Byrne, R. A. & Kastrati, A. Lancet, (2016).  

Higher Serum Asymmetric Dimethylarginine Is Related to Higher Risk of Heart Failure in the Epic-Potsdam Study. Wirth, J., Atzler, D., di Giuseppe, R., Cordts, K., Menzel, J., Böger, R. H., Boeing, H., Weikert, C. & Schwedhelm, E. Amino Acids, (2016).  

Radiation Dose Levels of Retrospectively Ecg-Gated Coronary Ct Angiography Using 70-Kvp Tube Voltage in Patients with High or Irregular Heart Rates. Meyer, M., Haubenreisser, H., Schoepf, U. J., Vliegenthart, R., Ong, M. M., Doesch, C., Sudarski, S., Borggrefe, M., Schoenberg, S. O. & Henzler, T. Academic radiology, (2016).  

Individualized Vs. Group Exercise in Improving Quality of Life and Physical Activity in Patients with Cardiac Disease and Low Exercise Capacity: Results from the Doppelherz Trial. Christle, J. W., Schlumberger, A., Haller, B., Gloeckl, R., Halle, M. & Pressler, A. Disability and rehabilitation, 1-6, (2016).  

Cd70 Limits Atherosclerosis and Promotes Macrophage Function. Winkels, H., Meiler, S., Smeets, E., Lievens, D., Engel, D., Spitz, C., Burger, C., Rinne, P., Beckers, L., Dandl, A., Reim, S., Ahmadsei, M., Van den Bossche, J., Holdt, L. M., Megens, R. T., Schmitt, M., de Winther, M., Biessen, E. A., Borst, J., Faussner, A. et al. Thrombosis and haemostasis, (2016).  

Prevalence of Arterial Stiffness and the Risk of Myocardial Diastolic Dysfunction in Women. Seeland, U., Brecht, A., Nauman, A. T., Oertelt-Prigione, S., Ruecke, M., Knebel, F., Stangl, V. & Regitz-Zagrosek, V. Bioscience reports 36, (2016).  

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Atrial Fibrillation in Women: Treatment. Ko, D., Rahman, F., Martins, M. A., Hylek, E. M., Ellinor, P. T., Schnabel, R. B., Benjamin, E. J. & Christophersen, I. E. Nature reviews. Cardiology, (2016).  

Management of Antithrombotic Therapy after Bleeding in Patients with Coronary Artery Disease and/or Atrial Fibrillation: Expert Consensus Paper of the European Society of Cardiology Working Group on Thrombosis. Halvorsen, S., Storey, R. F., Rocca, B., Sibbing, D., Ten Berg, J., Grovel, E. L., Weiss, T. W., Collet, J. P., Andreotti, F., Gulba, D. C., Lip, G. Y., Husted, S., Vilahur, G., Morais, J., Verheugt, F. W., Lanas, A., Al-Shahi Salman, R., Steg, P. G., Huber, K. & Thrombosis, E. W. G. o. European heart journal, (2016).  

Disulfide-Activated Protein Kinase G I[Alpha] Regulates Cardiac Diastolic Relaxation and Fine-Tunes the Frank-Starling Response. Scotcher, J., Prysyazhna, O., Boguslavskyi, A., Kistamas, K., Hadgraft, N., Martin, E. D., Worthington, J., Rudyk, O., Cutillas, P. R., Cuello, F., Shattock, M. J., Marber, M. S., Conte, M. R., Greenstein, A., Greensmith, D. J., Venetucci, L., Timms, J. F. & Eaton, P. Nature communications, ("=!&).  

Macroautophagy Is Impaired in Old Murine Brain Tissue as Well as in Senescent Human Fibroblasts. Ott, C., König, J., Höhn, A., Jung, T. & Grune, T. Redox biology, (2016).  

Microrna-Based Therapy of Gata2-Deficient Vascular Disease. Hartmann, D., Fiedler, J., Sonnenschein, K., Just, A., Pfanne, A., Zimmer, K., Remke, J., Foinquinos, A., Butzlaff, M., Schimmel, K., Maegdefessel, L., Hilfiker-Kleiner, D., Lachmann, N., Schober, A., Froese, N., Heineke, J., Bauersachs, J., Batkai, S. & Thum, T. Circulation, (2016).  

Fractional Flow Reserve Derived by Coronary Computed Tomography Angiography : A Sophisticated Analysis Method for Detecting Hemodynamically Significant Coronary Stenosis. Baumann, S., Becher, T., Schoepf, U. J., Lossnitzer, D., Henzler, T., Akin, I., Borggrefe, M. & Renker, M. Herz, (2016).  

Reduced Autophagy Leads to an Impaired Ferritin Turnover in Senescent Fibroblasts. Ott, C., Konig, J., Hohn, A., Jung, T. & Grune, T. Free radical biology & medicine, (2016).  

Local Electrical Dyssynchrony During Atrial Fibrillation: Theoretical Considerations and Initial Catheter Ablation Results. Kuklik, P., Schaffer, B., Hoffmann, B. A., Ganesan, A. N., Schreiber, D., Moser, J. M., Akbulak, R. O., Sultan, A., Steven, D., Maesen, B., Schotten, U., Meyer, C. & Willems, S. PloS one 11, e0164236, (2016).  

Release Kinetics of High-Sensitivity Cardiac Troponins I and T and Troponin T Upstream Open Reading Frame Peptide (Tntuorf) in Clinically Induced Acute Myocardial Infarction. Liebetrau, C., Gaede, L., Wolter, J. S., Homann, J., Meyer, A., Dorr, O., Nef, H. M., Troidl, C., Hamm, C. W., Mollmann, H., Richards, A. M. & Pemberton, C. J. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 1-24, (2016).  

Sumoylation-Independent Activation of Calcineurin-Nfat-Signaling Via Sumo2 Mediates Cardiomyocyte Hypertrophy. Bernt, A., Rangrez, A. Y., Eden, M., Jungmann, A., Katz, S., Rohr, C., Muller, O. J., Katus, H. A., Sossalla, S. T., Williams, T., Ritter, O., Frank, D. & Frey, N. Scientific reports 6, 35758, (2016).  

Obesity and Type 2 Diabetes in Sub-Saharan Africans - Is the Burden in Today's Africa Similar to African Migrants in Europe? The Rodam Study. Agyemang, C., Meeks, K., Beune, E., Owusu-Dabo, E., Mockenhaupt, F. P., Addo, J., de Graft Aikins, A., Bahendeka, S., Danguah, I., Schulze, M. B., Spranger, J., Burr, T., Agyei-Baffour, P., Amoah, S. K., Galbete, C., Henneman, C., Klipstein-Grobusch, K., Nicolaou, M., Adeyemo, A., van Straalen, J. et al. BMC Med 14, 166, (2016).  

The Role of Perivascular Adipose Tissue in Obesity-Induced Vascular Dysfunction. Xia, N. & Li, H. British journal of pharmacology, (2016).  

Refractoriness in Human Atria: Time and Voltage Dependence of Sodium Channel Availability. Skibsbye, L., Jespersen, T., Christ, T., Maleckar, M. M., van den Brink, J., Tavi, P. & Koivumaki, J. T. Journal of molecular and cellular cardiology, (2016).  

Surgical Management of Driveline Infections in Patients with Left Ventricular Assist Devices. Pieri, M., Scandroglio, A. M., Muller, M., Pergantis, P., Kretzschmar, A., Kaufmann, F., Falk, V., Krabatsch, T., Arlt, G., Potapov, E. & Kukucka, M. Journal of cardiac surgery, (2016).  

The Assessment of Ischaemic Burden: Validation of a Functional Jeopardy Score against Cardiovascular Magnetic Resonance Perfusion Imaging. Hussain, S. T., Morton, G., De Silva, K., Jogiya, R., Schuster, A., Paul, M., Perera, D. & Nagel, E. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).  

Magnetic Resonance Imaging of Local and Remote Vascular Remodelling after Experimental Stroke. Yanev, P., Seevinck, P. R., Rudrapatna, U. S., Bouts, M. J. R. J., van der Toorn, A., Gertz, K., Kronenberg, G., Endres, M., van Tilborg, G. A. & Dijkhuizen, R. M. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (2016).  

High-Resolution Myocardial T1 Mapping Using Single-Shot Inversion-Recovery Fast Low-Angle Shot Mri with Radial Undersampling and Iterative Reconstruction. Wang, X., Joseph, A. A., Kalentev, O., Merboldt, K. D., Voit, D., Roeloffs, V. B., van Zalk, M. & Frahm, J., (2016).  

Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss During Neuromuscular Synapse Elimination. Brill, M. S., Kleele, T., Ruschkies, L., Wang, M., Marahori, N. A., Reuter, M. S., Hausrat, T. J., Weigand, E., Fisher, M., Ahles, A., Engelhardt, S., Bishop, D. L., Kneussel, M. & Misgeld, T. Neuron, (2016).  

Pregnancy and Cardiovascular Risk: A Review Focused on Women with Heart Disease Undergoing Fertility Treatment. Rossberg, N., Stangl, K. & Stangl, V. European journal of preventive cardiology, (2016).  

Antisera against Neisseria Gonorrhoeae Cross-React with Specific Brain Proteins of the Common Marmoset Monkey and Other Nonhuman Primate Species. Reuss, B., Asif, A. R., Almamy, A., Schwerk, C., Schroten, H., Ishikawa, H., Drummer, C. & Behr, R. Brain research, (2016).  

Immunbiologische Aspekte Der Stammzell- Und Engineered-Heart-Tissue-Transplantation. Guenther, S. P. W., Schrepfer, S., Reichenspurner, H. & Deuse, T. Z Herz- Thorax- Gefäßchir, 1-5, (2016).  

Egender - from E-Learning to E-Research: A Web-Based Interactive Knowledge-Sharing Platform for Sex- and Gender-Specific Medical Education. Seeland, U., Nauman, A. T., Cornelis, A., Ludwig, S., Dunkel, M., Kararigas, G. & Regitz-Zagrosek, V. Biol Sex Diff 7, 39.  

Integrating Topics of Sex and Gender into Medical Curricula - Lessons from the International Community. Miller, V. J., Kararigas, G., Seeland, U., Regitz-Zagrosek, V., Kublickiene, K., Einstein, G., Casanova, R. & Legato, M. J. Biol Sex Diff 7, 44, (2016).  

Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity. Yin, C., Mohanta, S. K., Srikakulapu, P., Weber, C. & Habenicht, A. J. Frontiers in immunology 7, 387, (2016).  

Biventricular Support Using 2 Heartmate 3 Pumps. Potapov, E. V., Kukucka, M., Falk, V. & Krabatsch, T. J Heart Lung Transplant 35, 1268-1270, (2016).

Recalibration of the Acc/Aha Risk Score in Two Population-Based German Cohorts. de Las Heras Gala, T., Geisel, M. H., Peters, A., Thorand, B., Baumert, J., Lehmann, N., Jockel, K. H., Moebus, S., Erbel, R., Meisinger, C., Mahabadi, A. A., Koenig, W., Group, K. S. & the Heinz Nixdorf Recall Study, G. PloS one 11, e0164688, (2016).  

Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation. Jansen, H., Willenborg, C., Lieb, W., Zeng, L., Ferrario, P. G., Loley, C., König, I. R., Erdmann, J., Samani, N. J. & Schunkert, H. J Rheumatol, (2016).  

Titin Forms Circles: Regulation by Heart Failure and the Rna-Binding Protein Rbm20. Jae, N. & Dimmeler, S. Circulation research 119, 966-968, (2016).  

N-Acetyl-L-Cysteine Inhibits Sulfur Mustard-Induced and Trpa1-Dependent Calcium Influx. Stenger, B., Popp, T., John, H., Siegert, M., Tsoutsoulopoulos, A., Schmidt, A., Muckter, H., Gudermann, T., Thiermann, H. & Steinritz, D. Archives of toxicology, (2016).  

Coronary Artery Ectasia Are Frequently Observed in Patients with Bicuspid Aortic Valves with and without Dilatation of the Ascending Aorta. Meindl, C., Achatz, B., Huber, D., Baessler, A., Hubauer, U., Meisinger, C., Hengstenberg, C., Erdmann, J., Buchner, S., Maier, L., Schunkert, H., Debl, K. & Fischer, M. Circulation. Cardiovascular interventions 9, (2016).  

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Loley, C., Alver, M., Assimes, T. L., Bjonnes, A., Goel, A., Gustafsson, S., Hernesniemi, J., Hopewell, J. C., Kanoni, S., Kleber, M. E., Lau, K. W., Lu, Y., Lyytikainen, L. P., Nelson, C. P., Nikpay, M., Qu, L., Salfati, E., Scholz, M., Tukiainen, T., Willenborg, C. et al. Scientific reports 6, 35278, (2016).  

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Relation of Early and Late Stages of Glucose Metabolism Disturbances with Left Ventricular Geometry and Function: Are Sugar Kisses Bad for the Heart? Markus, M. R. & Dorr, M. Circulation. Cardiovascular imaging 9, (2016).

Fast Comprehensive Single-Sequence Four-Dimensional Pediatric Knee Mri with T2 Shuffling. Bao, S., Tamir, J. I., Young, J. L., Tariq, U., Uecker, M., Lai, P., Chen, W., Lustig, M. & Vasanawala, S. S. Journal of magnetic resonance imaging : JMRI, (2016).

Bimodal Antagonism of Pka Signalling by Arhgap36. Eccles, R. L., Czajkowski, M. T., Barth, C., Muller, P. M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zuhlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbe, S. & Rocks, O. Nature communications 7, 12963, (2016).  

The Gut Microbiome as Therapeutic Target in Central Nervous System Diseases: Implications for Stroke. Winek, K., Dirnagl, U. & Meisel, A. Neurotherapeutics, (2016).  

Concomitant Implantation of Impella(R) on Top of Veno-Arterial Extracorporeal Membrane Oxygenation May Improve Survival of Patients with Cardiogenic Shock. Pappalardo, F., Schulte, C., Pieri, M., Schrage, B., Contri, R., Soeffker, G., Greco, T., Lembo, R., Mullerleile, K., Colombo, A., Sydow, K., De Bonis, M., Wagner, F., Reichenspurner, H., Blankenberg, S., Zangrillo, A. & Westermann, D. European journal of heart failure, (2016).  

Metabolic Fingerprints of Circulating Igf-I and the Igf-I/Igfbp-3 Ratio: A Multi-Fluid Metabolomics Study. Knacke, H., Pietzner, M., Do, K. T., Romisch-Margl, W., Kastenmuller, G., Volker, U., Volzke, H., Krumsiek, J., Artati, A., Wallaschofski, H., Nauck, M., Suhre, K., Adamski, J. & Friedrich, N. The Journal of clinical endocrinology and metabolism, jc20162588, (2016).  

S100a4 Protects the Myocardium against Ischemic Stress. Doroudgar, S., Quijada, P., Konstandin, M., Ilves, K., Broughton, K., Khalafalla, F. G., Casillas, A., Nguyen, K., Gude, N., Toko, H., Ornelas, L., Thuerauf, D. J., Glembotski, C. C., Sussman, M. A. & Volkers, M. Journal of molecular and cellular cardiology, (2016).  

Nt-Probnp Predicts Cardiovascular Death in the General Population Independent of Left Ventricular Mass and Function: Insights from a Large Population-Based Study with Long-Term Follow-Up. Dietl, A., Stark, K., Zimmermann, M. E., Meisinger, C., Schunkert, H., Birner, C., Maier, L. S., Peters, A., Heid, I. M. & Luchner, A. PloS one 11, e0164060, (2016).  

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease. Finan, B., Clemmensen, C., Zhu, Z., Stemmer, K., Gauthier, K., Muller, L., De Angelis, M., Moreth, K., Neff, F., Perez-Tilve, D., Fischer, K., Lutter, D., Sanchez-Garrido, M. A., Liu, P., Tuckermann, J., Malehmir, M., Healy, M. E., Weber, A., Heikenwalder, M., Jastroch, M. et al. Cell, (2016).  

Impact of Concomitant Atrial Fibrillation on the Prognosis of Takotsubo Cardiomyopathy. El-Battrawy, I., Lang, S., Ansari, U., Behnes, M., Hillenbrand, D., Schramm, K., Fastner, C., Zhou, X., Bill, V., Hoffmann, U., Papavassiliu, T., Elmas, E., Haghi, D., Borggrefe, M. & Akin, I. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).  

Cryoballoon Vs. Radiofrequency Ablation for Paroxysmal Atrial Fibrillation: An Updated Meta-Analysis of Randomized and Observational Studies. Buiatti, A., von Olshausen, G., Barthel, P., Schneider, S., Luik, A., Kaess, B., Laugwitz, K. L. & Hoppmann, P. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).  

Inhibition of Net Release Fails to Reduce Adipose Tissue Inflammation in Mice. Braster, Q., Silvestre Roig, C., Hartwig, H., Beckers, L., den Toom, M., Doring, Y., Daemen, M. J., Lutgens, E. & Soehnlein, O. PloS one 11, e0163922, (2016).  

Camp-Dependent Protein Kinase a (Pka) Regulates Angiogenesis by Modulating Tip Cell Behavior in a Notch-Independent Manner. Nedvetsky, P. I., Zhao, X., Mathivet, T., Aspalter, I. M., Stanchi, F., Metzger, R. J., Mostov, K. E. & Gerhardt, H. Development 143, 3582-3590, (2016).  

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A Randomised Trial on Platelet Function-Guided De-Escalation of Antiplatelet Treatment in Acs Patients Undergoing Pci. Rationale and Design of the Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes (Tropical-Acs) Trial. Sibbing, D., Aradi, D., Jacobshagen, C., Gross, L., Trenk, D., Geisler, T., Orban, M., Gori, T., Hadamitzky, M., Merkely, B., Kiss, R. G., Komocsi, A., Dezsi, C. A., Thalmeier, A., Low, A., Holdt, L., Teupser, D., Ince, H., Felix, S. B., Parma, R. et al. Thrombosis and haemostasis 117, (2016). 

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model. Riegler, J., Tiburcy, M., Ebert, A., Tzatzalos, E., Raaz, U., Abilez, O. J., Shen, Q., Kooreman, N. G., Neofytou, E., Chen, V. C., Wang, M., Meyer, T., Tsao, P. S., Connolly, A. J., Couture, L. A., Gold, J. D., Zimmermann, W. H. & Wu, J. C. Circulation research 117, 720-730, (2015).  

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35–74 Years) General Population: A Cross-Sectional Study in Six European Countries. Stuetz, W., Weber, D., Dolle, M. E. T., Jansen, E., Grubeck-Loebenstein, B., Fiegl, S., Toussaint, O., Bernhardt, J., Gonos, E. S., Franceschi, C., Sikora, E., Moreno-Villanueva, M., Breusing, N., Grune, T. & Bürkle, A. Nutrients 8, 614, (2016).  

Real-Time Mri of Swallowing: Intraoral Pressure Reduction Supports Larynx Elevation. Olthoff, A., Joseph, A. A., Weidenmuller, M., Riley, B. & Frahm, J. NMR in biomedicine, (2016).  

Association of Periodontal Destruction and Diabetes with Mortality. Kebede, T. G., Holtfreter, B., Kocher, T., Meisel, P., Dietrich, T., Biffar, R., Dorr, M., Volzke, H. & Pink, C. Journal of dental research, (2016).  

A Simple, Non-Invasive Score to Predict Paroxysmal Atrial Fibrillation. Kallenberger, S. M., Schmid, C., Wiedmann, F., Mereles, D., Katus, H. A., Thomas, D. & Schmidt, C. PloS one 11, e0163621, (2016).  

Bifurcation Intervention with a Two-Stent Strategy: Can One Size Fit All? Colleran, R., Byrne, R. A. & Kastrati, A. European heart journal, (2016).  

Enhanced Cardiac Tbc1d10c Expression Lowers Heart Rate and Enhances Exercise Capacity and Survival. Volland, C., Bremer, S., Hellenkamp, K., Hartmann, N., Dybkova, N., Khadjeh, S., Kutschenko, A., Liebetanz, D., Wagner, S., Unsold, B., Didie, M., Toischer, K., Sossalla, S., Hasenfuss, G. & Seidler, T. Scientific reports 6, 33853, (2016).  

Hypothesis: Irisin Is a Metabolic Trigger for the Activation of the Neurohormonal Axis Governing Puberty Onset. Wahab, S., Shahab, M. & Behr, E. R. Med Hypotheses 95, 1-4, (2016).  

Off-Pump Implantation of the Heartmate 3 Left Ventricular Assist Device through Bilateral Thoracotomy Approach. Potapov, E. V., Kukucka, M., Falk, V. & Krabatsch, T. J Thorac Cardiovasc Surg, (2016).  

52 Genetic Loci Influencing Myocardial Mass. van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikainen, L. P., Polasek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Muller-Nurasyid, M. et al. Journal of the American College of Cardiology 68, 1435-1448, (2016).  

Gynecological Practice Represents the Ideal Setting for Early Opportunistic Cardiovascular Prevention: A Cross-Sectional Survey in an Urban Female Population. Oertelt-Prigione, S., Ruecke, M., Seeland, U. & Regitz-Zagrosek, V. Journal of women's health, (2016).  

Reduction of Apoptosis and Preservation of Mitochondrial Integrity under Ischemia/Reperfusion Injury Is Mediated by Estrogen Receptor Β. Schubert, C., Raparelli, V., Westphal, C., Dworatzek, E., Petrov, G., Kararigas, G. & Regitz-Zagrosek, V. Biol Sex Diff 7, (2016).  

Cathepsin G Controls Arterial but Not Venular Myeloid Cell Recruitment. Ortega-Gomez, A., Salvermoser, M., Roissant, J., Pick, R., Brauner, J., Lemnitzer, P., Tilgner, J., de Jong, R., Megens, R. T. A., Jamasbi, J., Döring, Y., Pham, C. T., Scheiermann, C., Siess, W., Drechsler, M., Weber, C., Grommes, J., Zarbock, J., Walzog, B. & Soehnlein, O. Circulation, (2016).  

Biophysical Tools to Assess the Interaction of Pf4 with Polyanions. Delcea, M. & Greinacher, A. Thrombosis and haemostasis 116, (2016).  

Reduced Bone Stiffness in Women Is Associated with Clinical Attachment and Tooth Loss: The Study of Health in Pomerania. Silveira, J. L., Albers, M., Vargas, D. M., Santa Helena, E. T., Cordova, C. M., Hannemann, A., Wallaschofski, H., Meisel, P., Pink, C., Samietz, S., Schmidt, C. O., Holtfreter, B., Volzke, H., Dorr, M., Kocher, T. & Markus, M. R. Journal of dental research, (2016).  

Genomic Prediction of Coronary Heart Disease. Abraham, G., Havulinna, A. S., Bhalala, O. G., Byars, S. G., De Livera, A. M., Yetukuri, L., Tikkanen, E., Perola, M., Schunkert, H., Sijbrands, E. J., Palotie, A., Samani, N. J., Salomaa, V., Ripatti, S. & Inouye, M. European heart journal, (2016).  

Endothelial Cell Senescence and Thrombosis: Ageing Clots. Bochenek, M. L., Schutz, E. & Schafer, K. Thrombosis research 147, 36-45, (2016).  

Right Insular Infarction and Mortality after Ischaemic Stroke. Hanne, L., Brunecker, P., Grittner, U., Endres, M., Villringer, K., Fiebach, J. B. & Ebinger, M. European journal of neurology, (2016).   

Axial Tubule Junctions Control Rapid Calcium Signaling in Atria. Brandenburg, S., Kohl, T., Williams, G. S., Gusev, K., Wagner, E., Rog-Zielinska, E. A., Hebisch, E., Dura, M., Didie, M., Gotthardt, M., Nikolaev, V. O., Hasenfuss, G., Kohl, P., Ward, C. W., Lederer, W. J. & Lehnart, S. E. The Journal of clinical investigation, (2016).  

Antiarrhythmic Effects of Dantrolene in Human Diseased Cardiomyocytes. Hartmann, N., Pabel, S., Herting, J., Schatter, F., Renner, A., Gummert, J., Schotola, H., Danner, B. C., Maier, L. S., Frey, N., Hasenfuss, G., Fischer, T. H. & Sossalla, S. Heart rhythm : the official journal of the Heart Rhythm Society, (2016).  

Association between Transcatheter Aortic Valve Replacement and Subsequent Infective Endocarditis and in-Hospital Death. Regueiro, A., Linke, A., Latib, A., Ihlemann, N., Urena, M., Walther, T., Husser, O., Herrmann, H. C., Nombela-Franco, L., Cheema, A. N., Le Breton, H., Stortecky, S., Kapadia, S., Bartorelli, A. L., Sinning, J. M., Amat-Santos, I., Munoz-Garcia, A., Lerakis, S., Gutierrez-Ibanes, E., Abdel-Wahab, M. et al. Jama 316, 1083-1092, (2016).  

Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions. Uzun, A. U., Mannhardt, I., Breckwoldt, K., Horvath, A., Johannsen, S. S., Hansen, A., Eschenhagen, T. & Christ, T. Frontiers in pharmacology 7, 300, (2016).  

Skeletal Muscle Alterations Are Exacerbated in Heart Failure with Reduced Compared with Preserved Ejection Fraction: Mediated by Circulating Cytokines? Seiler, M., Bowen, T. S., Rolim, N., Dieterlen, M. T., Werner, S., Hoshi, T., Fischer, T., Mangner, N., Linke, A., Schuler, G., Halle, M., Wisloff, U. & Adams, V. Circulation. Heart failure 9, (2016).   

Blood Rna Expression Profiles Undergo Major Changes During the Seventh Decade. Gheorghe, M., Schurmann, C., Peters, M. J., Uitterlinden, A., Hofman, A., Biffar, R., Homuth, G., Volker, U., van Meurs, J. B. & Raz, V. Oncotarget (2016).  

Can Erythrocytes Release Biologically Active No? Benz, P. M. & Fleming, I. Cell communication and signaling : CCS 14, 22, (2016).  

Black-Blood Native T1 Mapping: Blood Signal Suppression for Reduced Partial Voluming in the Myocardium. Weingartner, S., Messner, N. M., Zollner, F. G., Akcakaya, M. & Schad, L. R. Magnetic resonance in medicine, (2016).  

Rna Therapeutics for Treatment of Cardiovascular Diseases: Promises and Challenges. Lucas, T. & Dimmeler, S. Circulation research 119, 794-797, (2016).  

Is Stimulation of Cardiomyocyte Renewal a Facette of Reversible Catecholamine Toxicity? Eschenhagen, T. Circulation research 119, 779-781, (2016).  

Six Versus Twelve Months Clopidogrel Therapy after Drug-Eluting Stenting in Patients with Acute Coronary Syndrome: An Isar-Safe Study Subgroup Analysis. Lohaus, R., Michel, J., Mayer, K., Lahmann, A. L., Byrne, R. A., Wolk, A., Ten Berg, J. M., Neumann, F. J., Han, Y., Adriaenssens, T., Tolg, R., Seyfarth, M., Maeng, M., Zrenner, B., Jacobshagen, C., Wohrle, J., Kufner, S., Morath, T., Ibrahim, T., Bernlochner, I. et al. Scientific reports 6, 33054, (2016).

Biodegradable-Polymer Drug-Eluting Stents: Back to the Future? Cassese, S., Xhepa, E. & Kastrati, A. Heart, (2016).  

Nox2 Amplifies Acetaldehyde-Mediated Cardiomyocyte Mitochondrial Dysfunction in Alcoholic Cardiomyopathy. Brandt, M., Garlapati, V., Oelze, M., Sotiriou, E., Knorr, M., Kroller-Schon, S., Kossmann, S., Schonfelder, T., Morawietz, H., Schulz, E., Schultheiss, H. P., Daiber, A., Munzel, T. & Wenzel, P. Scientific reports 6, 32554, (2016).  

Comparison of Coronary Computed Tomography Angiography-Derived Vs Invasive Fractional Flow Reserve Assessment: Meta-Analysis with Subgroup Evaluation of Intermediate Stenosis. Baumann, S., Renker, M., Hetjens, S., Fuller, S. R., Becher, T., Lossnitzer, D., Lehmann, R., Akin, I., Borggrefe, M., Lang, S., Wichmann, J. L. & Schoepf, U. J. Academic radiology, (2016).  

Uptake of Citrate-Coated Iron Oxide Nanoparticles into Atherosclerotic Lesions in Mice Occurs Via Accelerated Transcytosis through Plaque Endothelial Cells. Poller, W., Ramberger, E., Bohm-Sturm, P., Muller, S., Moller, K., Lowa, N., Wiekhorst, F., Wagner, S., Taupitz, M., Schellenberger, E., Baumann, G., Stangl, K., Stangl, V. & Ludwig, A. Nano Research, (2016).  

The Analysis of Heterotaxy Patients Reveals New Loss-of-Function Variants of Grk5. Lessel, D., Muhammad, T., Casar Tena, T., Moepps, B., Burkhalter, M. D., Hitz, M. P., Toka, O., Rentzsch, A., Schubert, S., Schalinski, A., Bauer, U. M., Kubisch, C., Ware, S. M. & Philipp, M. Scientific reports 6, 33231, (2016).  

Vasodilator-Stimulated Phosphoprotein (Vasp)-Dependent and -Independent Pathways Regulate Thrombin-Induced Activation of Rap1b in Platelets. Benz, P. M., Laban, H., Zink, J., Gunther, L., Walter, U., Gambaryan, S. & Dib, K. Cell communication and signaling : CCS 14, 21, (2016).  

Dicer Generates a Regulatory Microrna Network in Smooth Muscle Cells That Limits Neointima Formation During Vascular Repair. Zahedi, F., Nazari-Jahantigh, M., Zhou, Z., Subramanian, P., Wei, Y., Grommes, J., Offermanns, S., Steffens, S., Weber, C. & Schober, A. Cellular and molecular life sciences : CMLS, (2016).  

Trans-Ancestry Meta-Analyses Identify Rare and Common Variants Associated with Blood Pressure and Hypertension. Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. et al. Nature genetics, (2016).  

Identification of Novel Antigens Contributing to Autoimmunity in Cardiovascular Diseases. Muller, A. M., Bockstahler, M., Hristov, G., Weiss, C., Fischer, A., Korkmaz-Icoz, S., Giannitsis, E., Poller, W., Schultheiss, H. P., Katus, H. A. & Kaya, Z. Clinical immunology, (2016).  

Meta-Analysis Identifies Common and Rare Variants Influencing Blood Pressure and Overlapping with Metabolic Trait Loci. Liu, C., Kraja, A. T., Smith, J. A., Brody, J. A., Franceschini, N., Bis, J. C., Rice, K., Morrison, A. C., Lu, Y., Weiss, S., Guo, X., Palmas, W., Martin, L. W., Chen, Y. I., Surendran, P., Drenos, F., Cook, J. P., Auer, P. L., Chu, A. Y., Giri, A. et al. Nature genetics, (2016).  

The Genetics of Blood Pressure Regulation and Its Target Organs from Association Studies in 342,415 Individuals. Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A. K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., Shah, S. et al. Nature genetics, (2016).  

Gender Differences in Appropriate Shocks and Mortality among Patients with Primary Prophylactic Implantable Cardioverter-Defibrillators: Systematic Review and Meta-Analysis. Conen, D., Arendacka, B., Rover, C., Bergau, L., Munoz, P., Wijers, S., Sticherling, C., Zabel, M. & Friede, T. PloS one 11, e0162756, (2016).   

Predicting 10-Year Risk of Fatal Cardiovascular Disease in Germany: An Update Based on the Score-Deutschland Risk Charts. Rucker, V., Keil, U., Fitzgerald, A. P., Malzahn, U., Prugger, C., Ertl, G., Heuschmann, P. U. & Neuhauser, H. PloS one 11, e0162188, (2016).  

Generation of Functional Cardiomyocytes from the Synoviocytes of Patients with Rheumatoid Arthritis Via Induced Pluripotent Stem Cells. Lee, J., Jung, S. M., Ebert, A. D., Wu, H., Diecke, S., Kim, Y., Yi, H., Park, S. H. & Ju, J. H. Scientific reports 6, 32669, (2016).  

The a-Kinase Anchoring Protein (Akap) Glycogen Synthase Kinase 3beta Interaction Protein (Gskip) Regulates Beta-Catenin through Its Interactions with Both Protein Kinase a (Pka) and Gsk3beta. Dema, A., Schroter, M. F., Perets, E., Skroblin, P., Moutty, M. C., Deak, V. A., Birchmeier, W. & Klussmann, E. The Journal of biological chemistry 291, 19618-19630, (2016).  

Endomyocardial Proteomic Signature Corresponding to the Response of Patients with Dilated Cardiomyopathy to Immunoadsorption Therapy. Gourav, B., Dorr, M., Sappa, P. K., Ameling, S., Dhople, V., Steil, L., Klingel, K., Empen, K., Beug, D., Volker, U., Felix, S. B. & Hammer, E. Journal of proteomics, (2016).  

Characterization of the Metabolic Profile Associated with Serum 25-Hydroxyvitamin D: A Cross-Sectional Analysis in Population-Based Data. Vogt, S., Wahl, S., Kettunen, J., Breitner, S., Kastenmuller, G., Gieger, C., Suhre, K., Waldenberger, M., Kratzsch, J., Perola, M., Salomaa, V., Blankenberg, S., Zeller, T., Soininen, P., Kangas, A. J., Peters, A., Grallert, H., Ala-Korpela, M. & Thorand, B. International journal of epidemiology, (2016).  

Angiopoietin-2, Its Soluble Receptor Tie-2, and Metabolic Syndrome Components in a Population-Based Sample. Lorbeer, R., Baumeister, S. E., Dorr, M., Nauck, M., Grotevendt, A., Schlesinger, S., Teumer, A., Volzke, H., Grabe, H. J., Wallaschofski, H., Vasan, R. S. & Lieb, W. Obesity, (2016).  

Local Multi-Channel Rf Surface Coil Versus Body Rf Coil Transmission for Cardiac Magnetic Resonance at 3 Tesla: Which Configuration Is Winning the Game? Weinberger, O., Winter, L., Dieringer, M. A., Els, A., Oezerdem, C., Rieger, J., Kuehne, A., Cassara, A. M., Pfeiffer, H., Wetterling, F. & Niendorf, T. PloS one 11, e0161863, (2016).  

Transaortic Transcatheter Aortic Valve Implantation: Experience from the Kiel Study. Petzina, R., Lutter, G., Wolf, C., Kuhl, C., Freitag-Wolf, S., Panholzer, B., Bramlage, P., Frey, N., Cremer, J. & Frank, D. Interactive cardiovascular and thoracic surgery, (2016).  

Antiarrhythmic Gene Therapy - Will Biologics Replace Catheters, Drugs and Devices? Lugenbiel, P., Schweizer, P. A., Katus, H. A. & Thomas, D. European journal of pharmacology, (2016).  

Development of Nonfibrotic Left Ventricular Hypertrophy in an Ang Ii-Induced Chronic Ovine Hypertension Model. Klatt, N., Scherschel, K., Schad, C., Lau, D., Reitmeier, A., Kuklik, P., Muellerleile, K., Yamamura, J., Zeller, T., Steven, D., Baldus, S., Schaffer, B., Jungen, C., Eickholt, C., Wassilew, K., Schwedhelm, E., Willems, S. & Meyer, C. Physiological reports 4, (2016).  

Adenosine-to-Inosine Rna Editing Controls Cathepsin S Expression in Atherosclerosis by Enabling Hur-Mediated Post-Transcriptional Regulation. Stellos, K., Gatsiou, A., Stamatelopoulos, K., Perisic Matic, L., John, D., Lunella, F. F., Jae, N., Rossbach, O., Amrhein, C., Sigala, F., Boon, R. A., Furtig, B., Manavski, Y., You, X., Uchida, S., Keller, T., Boeckel, J. N., Franco-Cereceda, A., Maegdefessel, L., Chen, W. et al. Nature medicine, (2016).   

Letter by Baumann Et Al Regarding Article, "Fractional Flow Reserve and Coronary Computed Tomographic Angiography: A Review and Critical Analysis". Baumann, S., Tesche, C., Schoepf, U. J., Akin, I., Borggrefe, M. & Renker, M. Circulation research 119, e106-107, (2016).  

Gut Microbiota Promote Angiotensin Ii-Induced Arterial Hypertension and Vascular Dysfunction. Karbach, S. H., Schonfelder, T., Brandao, I., Wilms, E., Hormann, N., Jackel, S., Schuler, R., Finger, S., Knorr, M., Lagrange, J., Brandt, M., Waisman, A., Kossmann, S., Schafer, K., Munzel, T., Reinhardt, C. & Wenzel, P. Journal of the American Heart Association 5, (2016).

[Op.7d.01] Safety and Blood Pressure Effects of Second- Versus First-Generation System for Administering Baroreflex Activation Therapy. Wachter, R., Halbach, M., Bakris, G., Bisognano, J., Haller, H., Beige, J., Kroon, A. A., Nadim, M., Lovett, E., Schafer, J. & de Leeuw, P. W. Journal of hypertension 34 Suppl 2, e94, (2016).  

Influence of Electrode Positioning on Accuracy and Reproducibility of Electrical Velocimetry Cardiac Output Measurements. Trinkmann, F., Berger, M., Michels, J. D., Doesch, C., Weiss, C., Schoenberg, S. O., Akin, I., Borggrefe, M., Papavassiliu, T. & Saur, J. Physiological measurement 37, 1422-1435, (2016).  

Monocytes Chat with Atherosclerotic Lesions. Soehnlein, O. Arteriosclerosis, thrombosis, and vascular biology 36, 1720-1721, (2016).  

Joint Statement of the European Association for the Study of Obesity and the European Society of Hypertension: Obesity and Heart Failure. Jordan, J., Toplak, H., Grassi, G., Yumuk, V., Kotsis, V., Engeli, S., Cuspidi, C., Nilsson, P. M., Finer, N. & Doehner, W. Journal of hypertension 34, 1678-1688, (2016).  


Ghrelin and Hormonal Markers under Exercise Training in Patients with Heart Failure with Preserved Ejection Fraction: Results from the Ex-Dhf Pilot Study. Trippel, T., Holzendorf, V., Halle, M., Gelbrich, G., Nolte, K., Duvinage, A., Schwarz, S., Rutscher, T., Wiora, J., Wachter, R., Herrmann-Lingen, C., Duengen, H. D., Hasenfuss, G. & Pieske, B. ESC Heart Failure, (2016).   

Prognostic Usefulness of the Ballooning Pattern in Patients with Takotsubo Cardiomyopathy. Stiermaier, T., Möller, C., Graf, T., Eitel, C., Desch, S., Thiele, H. & Eitel, I. The American Journal of Cardiology, (2016).  

Cardiac Contractility Modulation in Heart Failure Patients: Randomized Comparison of Signal Delivery through One Vs. Two Ventricular Leads. Roger, S., Said, S., Kloppe, A., Lawo, T., Emig, U., Rousso, B., Gutterman, D., Borggrefe, M. & Kuschyk, J. Journal of cardiology, (2016).  

Crispr/Cas9-Mediated Knockout of P22phox Leads to Loss of Nox1 and Nox4, but Not Nox5 Activity. Prior, K. K., Leisegang, M. S., Josipovic, I., Lowe, O., Shah, A. M., Weissmann, N., Schroder, K. & Brandes, R. P. Redox biology 9, 287-295, (2016).  

Maternal Cardiac Deceleration Capacity: A Novel Insight into Maternal Autonomic Function in Pregnancies Complicated by Hypertensive Disorders and Intrauterine Growth Restriction. Casati, D., Stampalija, T., Ferrazzi, E., Alberti, A. M., Scebba, I., Paganelli, A., Di Martino, D., Muggiasca, M. L. & Bauer, A. European journal of obstetrics, gynecology, and reproductive biology 206, 6-11, (2016).  

Left Ventricular Assist Devices-Current State and Perspectives. Prinzing, A., Herold, U., Berkefeld, A., Krane, M., Lange, R. & Voss, B. Journal of thoracic disease 8, E660-666, (2016).  

Prognostic Usefulness of the Ballooning Pattern in Patients with Takotsubo Cardiomyopathy. Stiermaier, T., Möller, C., Graf, T., Eitel, C., Desch, S., Thiele, H. & Eitel, I. The American Journal of Cardiology, (2016).  

Cardiac Contractility Modulation in Heart Failure Patients: Randomized Comparison of Signal Delivery through One Vs. Two Ventricular Leads. Roger, S., Said, S., Kloppe, A., Lawo, T., Emig, U., Rousso, B., Gutterman, D., Borggrefe, M. & Kuschyk, J. Journal of cardiology, (2016).  

Late Outcomes after Acute Pulmonary Embolism: Rationale and Design of Focus, a Prospective Observational Multicenter Cohort Study. Konstantinides, S. V., Barco, S., Rosenkranz, S., Lankeit, M., Held, M., Gerhardt, F., Bruch, L., Ewert, R., Faehling, M., Freise, J., Ghofrani, H. A., Grunig, E., Halank, M., Heydenreich, N., Hoeper, M. M., Leuchte, H. H., Mayer, E., Meyer, F. J., Neurohr, C., Opitz, C. et al. Journal of thrombosis and thrombolysis, (2016).  

Genotype-Phenotype Associations in Dilated Cardiomyopathy: Meta-Analysis on More Than 8000 Individuals. Kayvanpour, E., Sedaghat-Hamedani, F., Amr, A., Lai, A., Haas, J., Holzer, D. B., Frese, K. S., Keller, A., Jensen, K., Katus, H. A. & Meder, B. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).  

Disulfide Hmgb1 Derived from Platelets Coordinates Venous Thrombosis in Mice. Stark, K., Philippi, V., Stockhausen, S., Busse, J., Antonelli, A., Miller, M., Schubert, I., Hoseinpour, P., Chandraratne, S., von Bruhl, M. L., Gartner, F., Lorenz, M., Agresti, A., Coletti, R., Antoine, D. J., Heermann, R., Jung, K., Reese, S., Laitinen, I., Schwaiger, M. et al. Blood, (2016).  

Antiplatelet Strategies in Elderly People: Still a Long Way to Go. Sibbing, D. & Massberg, S. Lancet, (2016).  

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. van der Laan, S. W., Fall, T., Soumare, A., Teumer, A., Sedaghat, S., Baumert, J., Zabaneh, D., van Setten, J., Isgum, I., Galesloot, T. E., Arpegard, J., Amouyel, P., Trompet, S., Waldenberger, M., Dorr, M., Magnusson, P. K., Giedraitis, V., Larsson, A., Morris, A. P., Felix, J. F. et al. Journal of the American College of Cardiology 68, 934-945, (2016).    

Principles of Cardiovascular Magnetic Resonance Feature Tracking and Echocardiographic Speckle Tracking for Informed Clinical Use. Pedrizzetti, G., Claus, P., Kilner, P. J. & Nagel, E. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 18, 51, (2016).  

[Invasive Treatment of Hypertension : Update 2016]. Menne, J. & Wachter, R. Der Internist, (2016).  

A Pan-Coronary Artery Angiographic Study of the Association between Diabetes Mellitus and Progression or Regression of Coronary Atherosclerosis. Iijima, R., Ndrepepa, G., Kujath, V., Harada, Y., Kufner, S., Schunkert, H., Nakamura, M. & Kastrati, A. Heart and vessels, (2016).  

Natural Killer Cell Reduction and Uteroplacental Vasculopathy. Golic, M., Haase, N., Herse, F., Wehner, A., Vercruysse, L., Pijnenborg, R., Balogh, A., Saether, P. C., Dissen, E., Luft, F. C., Przybyl, L., Park, J. K., Alnaes-Katjavivi, P., Staff, A. C., Verlohren, S., Henrich, W., Muller, D. N. & Dechend, R. Hypertension, (2016).  

Adverse Events Following International Normalized Ratio Reversal in Intracerebral Hemorrhage. Laible, M., Jenetzky, E., Beynon, C., Muller, O. J., Sander, P., Schuler, S., Purrucker, J., Mohlenbruch, M., Steiner, T., Veltkamp, R., Ringleb, P. A. & Rizos, T. Cerebrovascular diseases 42, 446-454, (2016).

Smoking and Clopidogrel Response Revisited: Hemoglobin Levels Explaining the Smoker's Paradox. Sibbing, D. & Gross, L. JACC. Cardiovascular interventions 9, 1691-1693, (2016).   

Viral Vector-Based Targeting of Mir-21 in Cardiac Non-Myocyte Cells Reduces Pathologic Remodeling of the Heart. Ramanujam, D., Sassi, Y., Laggerbauer, B. & Engelhardt, S. Molecular therapy : the journal of the American Society of Gene Therapy, (2016).  

A Reference Panel of 64,976 Haplotypes for Genotype Imputation. McCarthy, S., Das, S., Kretzschmar, W., Delaneau, O., Wood, A. R., Teumer, A., Kang, H. M., Fuchsberger, C., Danecek, P., Sharp, K., Luo, Y., Sidore, C., Kwong, A., Timpson, N., Koskinen, S., Vrieze, S., Scott, L. J., Zhang, H., Mahajan, A., Veldink, J. et al. Nature genetics, (2016).  

Drug-Coated Balloon Versus Plain Balloon Angioplasty for the Treatment of Femoropopliteal Artery Disease: An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials. Giacoppo, D., Cassese, S., Harada, Y., Colleran, R., Michel, J., Fusaro, M., Kastrati, A. & Byrne, R. A. JACC. Cardiovascular interventions 9, 1731-1742, (2016).  

Moving toward the Optimal Test for the Assessment of Myocardial Ischemia. Nagel, E. Journal of the American Heart Association 5, (2016).  

Deciphering Cardiac Involvement in Systemic Inflammatory Diseases: Noninvasive Tissue Characterisation Using Cardiac Magnetic Resonance Is Key to Improved Patients' Care. Gester, M., Peker, E., Nagel, E. & Puntmann, V. O. Expert review of cardiovascular therapy, (2016).  

Prognostic Utility of Galectin-3 for Recurrent Cardiovascular Events During Long-Term Follow-up in Patients with Stable Coronary Heart Disease: Results of the Karola Study. Jansen, H., Koenig, W., Jaensch, A., Mons, U., Breitling, L. P., Scharnagl, H., Stojakovic, T., Schunkert, H., Brenner, H. & Rothenbacher, D. Clinical chemistry, (2016).  

Partial Loss of Ve-Cadherin Improves Long-Term Outcome and Cerebral Blood Flow after Transient Brain Ischemia in Mice. Gertz, K., Kronenberg, G., Uhlemann, R., Prinz, V., Marquina, R., Corada, M., Dejana, E. & Endres, M. BMC neurology 16, 144, (2016).  

[Catheter-Based Closure of the Left Atrial Appendage : Stroke Prevention in Atrial Fibrillation]. Skurk, C., Leistner, D. M., Park, J. W. & Landmesser, U. Der Internist, (2016).  

Systems Medicine as an Emerging Tool for Cardiovascular Genetics Haase, T., Bornigen, D., Muller, C. & Zeller, T. Front. Cardiovasc. Med., (2016).  

Peptidase Inhibitor 16 Is a Membrane-Tethered Regulator of Chemerin Processing in the Myocardium. Regn, M., Laggerbauer, B., Jentzsch, C., Ramanujam, D., Ahles, A., Sichler, S., Calzada-Wack, J., Koenen, R., Braun, A., Nieswandt, B. & Engelhardt, S. Journal of molecular and cellular cardiology, (2016).  

Impact of Initial Culprit Vessel Flow on Infarct Size, Microvascular Obstruction, and Myocardial Salvage in Acute Reperfused St-Elevation Myocardial Infarction Joost, A., Stiermaier, T., Eitel, C., Fuernau, G., De Waha, S., Desch, S., Thiele, H. & Eitel, I. Am J Cardiol, (2016).  

Inhibition of Citrate Cotransporter Slc13a5/Mindy by Rnai Improves Hepatic Insulin Sensitivity and Prevents Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice. Brachs, S., Winkel, A. F., Tang, H., Birkenfeld, A. L., Brunner, B., Jahn-Hoffmann, K., Margerie, D., Ruetten, H., Schmoll, D. & Spranger, J. Molecular metabolism, (2016).  

Long-Term Prognostic Value of Risk Scores after Drug-Eluting Stent Implantation for Unprotected Left Main Coronary Artery: A Pooled Analysis of the Isar-Left-Main and Isar-Left-Main 2 Randomized Clinical Trials. Xhepa, E., Tada, T., Kufner, S., Ndrepepa, G., Byrne, R. A., Kreutzer, J., Ibrahim, T., Tiroch, K., Valgimigli, M., Tolg, R., Cassese, S., Fusaro, M., Schunkert, H., Laugwitz, K. L., Mehilli, J. & Kastrati, A. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, (2016).  

Interventional Re-Opening of a Pda for Reverse Potts Shunt Circulation after Ado I Implantation in a Child. Schubert, S., Peters, B. & Berger, F. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, (2016).  

Association of Serum Thyrotropin with Anthropometric Markers of Obesity in the General Population. Tiller, D., Ittermann, T., Greiser, K. H., Meisinger, C., Agger, C., Hofman, A., Thuesen, B., Linneberg, A., Peeters, R., Franco, O., Heier, M., Kluttig, A., Werdan, K., Stricker, B., Schipf, S., Markus, M., Dorr, M., Volzke, H. & Haerting, J. Thyroid : official journal of the American Thyroid Association, (2016).  

Erythrocytes Do Not Activate Purified and Platelet Soluble Guanylate Cyclases Even in Conditions Favourable for No Synthesis. Gambaryan, S., Subramanian, H., Kehrer, L., Mindukshev, I., Sudnitsyna, J., Reiss, C., Rukoyatkina, N., Friebe, A., Sharina, I., Martin, E. & Walter, U. Cell communication and signaling : CCS 14, 16, (2016).  

A Mediterranean-Style Diet, Its Components and the Risk of Heart Failure: A Prospective Population-Based Study in a Non-Mediterranean Country. Wirth, J., di Giuseppe, R., Boeing, H. & Weikert, C. European journal of clinical nutrition, (2016). 

3d-Black-Blood 3t-Mri for the Diagnosis of Thoracic Large Vessel Vasculitis: A Feasibility Study. Treitl, K. M., Maurus, S., Sommer, N. N., Kooijman-Kurfuerst, H., Coppenrath, E., Treitl, M., Czihal, M., Hoffmann, U., Dechant, C., Schulze-Koops, H. & Saam, T. European radiology, (2016).  

Sudden Cardiac Death Due to Deficiency of the Mitochondrial Inorganic Pyrophosphatase Ppa2. Kennedy, H., Haack, T. B., Hartill, V., Matakovic, L., Baumgartner, E. R., Potter, H., Mackay, R., Alston, C. L., O'Sullivan, S., McFarland, R., Connolly, G., Gannon, C., King, R., Mead, S., Crozier, I., Chan, W., Florkowski, C. M., Sage, M., Hofken, T., Alhaddad, B. et al. American journal of human genetics, (2016).  

Dataset of the Associations of Aldosterone to Renin Ratio with Mr-Proanp and Mr-Proadm. Then, C., Rottenkolber, M., Lechner, A., Meisinger, C., Heier, M., Koenig, W., Peters, A., Rathmann, W., Bidlingmaier, M., Reincke, M. & Seissler, J. Data in Brief, (2016).  

Survival, Quality of Life and Impact of Right Heart Failure in Patients with Acute Cardiogenic Shock Treated with Ecmo. Schoenrath, F., Hoch, D., Maisano, F., Starck, C. T., Seifert, B., Wenger, U., Ruschitzka, F. & Wilhelm, M. J. Heart & lung : the journal of critical care, (2016).  

A Mutation in the Glutamate-Rich Region of Rbm20 Causes Dilated Cardiomyopathy through Missplicing of Titin and Impaired Frank-Starling Mechanism. Beqqali, A., Bollen, I. A., Rasmussen, T. B., van den Hoogenhof, M. M., van Deutekom, H. W., Schafer, S., Haas, J., Meder, B., Sorensen, K. E., van Oort, R. J., Mogensen, J., Hubner, N., Creemers, E. E., van der Velden, J. & Pinto, Y. M. Cardiovascular research, (2016).  

Computational Cardiology - a New Discipline of Translational Research. Meder, B., Katus, H. A. & Keller, A. Genomics, proteomics & bioinformatics, (2016).

Association of a Congenital Long Qt Syndrome Type 1 with Takotsubo Cardiomyopathy. El-Battrawy, I., Behnes, M., Borggrefe, M. & Akin, I. Clin Case Rep 4, 789-792, (2016).  

Genetic Modifiers for the Long-Qt Syndrome: How Important Is the Role of Variants in the 3' Untranslated Region of Kcnq1? Crotti, L., Lahtinen, A. M., Spazzolini, C., Mastantuono, E., Monti, M. C., Morassutto, C., Parati, G., Heradien, M., Goosen, A., Lichtner, P., Meitinger, T., Brink, P. A., Kontula, K., Swan, H. & Schwartz, P. J. Circulation. Cardiovascular genetics 9, 330-339, (2016).  

Intraindividual Comparison of Everolimus-Eluting Bioresorbable Vascular Scaffolds Versus Drug-Eluting Metallic Stents. Cassese, S., Hoppmann, P., Kufner, S., Byrne, R. A., Wiebe, J., Colleran, R., Giacoppo, D., Harada, Y., Laugwitz, K. L., Schunkert, H., Fusaro, M. & Kastrati, A. Circulation. Cardiovascular interventions 9, (2016).

[Pulmonary Hypertension : What Is New in Therapy?]. Sommer, N., Hecker, M., Tello, K., Richter, M., Liebetrau, C., Weigand, M. A., Seeger, W., Ghofrani, A. & Gall, H. Der Anaesthesist, (2016).  

Posttraumatic Stress Disorder (Ptsd) Patients Exhibit a Blunted Parasympathetic Response to an Emotional Stressor. Meyer, T., Albrecht, J., Bornschein, G., Sachsse, U. & Herrmann-Lingen, C. Applied psychophysiology and biofeedback, (2016).  

Apolipoprotein a-I Gene Transfer Exerts Immunomodulatory Effects and Reduces Vascular Inflammation and Fibrosis in Ob/Ob Mice. Spillmann, F., De Geest, B., Muthuramu, I., Amin, R., Miteva, K., Pieske, B., Tschope, C. & Van Linthout, S. Journal of inflammation 13, 25, (2016).  

Untreated, Uncontrolled, and Apparent Resistant Hypertension: Results of the German Health Examination Survey 2008-2011. Sarganas, G. & Neuhauser, H. K. Journal of clinical hypertension, (2016).   

Heart Failure Epidemiology and Novel Treatments in Japan: Facts and Numbers. Konishi, M., Ishida, J., Springer, J., Von Haehling, S., Akashi, Y. J., Hiroaki, S. & Anker, S. D. ESC Heart Failure, (2016).

Safety and Efficacy in Ablation of Premature Ventricular Contraction: Data from the German Ablation Registry. Fichtner, S., Senges, J., Hochadel, M., Tilz, R., Willems, S., Eckardt, L., Deneke, T., Lewalter, T., Dorwarth, U., Reithmann, C., Brachmann, J., Steinbeck, G., Kaab, S. & German Ablation, R. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).

The Akap Gskip Regulates Beta-Catenin through Both Its Interactions with Pka and Gsk3beta. Dema, A., Schroeter, M. F., Perets, E., Skroblin, P., Moutty, M. C., Deak, V. A., Birchmeier, W. & Klussmann, E. The Journal of biological chemistry, (2016).

Distinct Genetic Architectures for Syndromic and Nonsyndromic Congenital Heart Defects Identified by Exome Sequencing. Sifrim, A., Hitz, M. P., Wilsdon, A., Breckpot, J., Turki, S. H., Thienpont, B., McRae, J., Fitzgerald, T. W., Singh, T., Swaminathan, G. J., Prigmore, E., Rajan, D., Abdul-Khaliq, H., Banka, S., Bauer, U. M., Bentham, J., Berger, F., Bhattacharya, S., Bu'Lock, F., Canham, N. et al. Nature genetics, (2016).

Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells. Anand, R., Strecker, V., Urbach, J., Wittig, I. & Reichert, A. S. PloS one 11, e0160258, (2016).


"Smoker's Paradox" in Patients with Cardiogenic Shock Complicating Myocardial Infarction - a Substudy of the Iabp-Shock Ii-Trial and Registry. Saad, M., Fuernau, G., Desch, S., Eitel, I., Jung, C., Poss, J., Schneider, S., Schuler, G., Werdan, K., Zeymer, U. & Thiele, H. International journal of cardiology 222, 775-779, (2016).   

Characterization of Circular Rnas in Human, Mouse and Rat Hearts. Werfel, S., Nothjunge, S., Schwarzmayr, T., Strom, T. M., Meitinger, T. & Engelhardt, S. Journal of molecular and cellular cardiology 98, 103-107, (2016).  

Takotsubo Syndrome and Embolic Events. El-Battrawy, I., Borggrefe, M. & Akin, I. Heart Failure Clinics (2016).   

Off-Pump Mitral Valved Stent Implantation: Comparison of Apical and Subannular Fixation Techniques. Pokorny, S., Huenges, K., Hansen, J. H., Schadow, Y., Fischer, G., Morlock, M. M., Cremer, J. & Lutter, G. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, (2016).  

Personalized Computer Simulation of Diastolic Function in Heart Failure. Amr, A., Kayvanpour, E., Sedaghat-Hamedani, F., Passerini, T., Mihalef, V., Lai, A., Neumann, D., Georgescu, B., Buss, S., Mereles, D., Zitron, E., Posch, A. E., Wurstle, M., Mansi, T., Katus, H. A. & Meder, B. Genomics, proteomics & bioinformatics, (2016).  

Reach of Individuals at Risk for Cardiovascular Disease by Proactive Recruitment Strategies in General Practices, Job Centers, and Health Insurance. Gurtler, D., Meyer, C., Dorr, M., Braatz, J., F., W., John, U., Freyer-Adam, J. & Ulbricht, S. International journal of behavioral medicine, (2016).  

The Role of Quality Control in Targeted Next-Generation Sequencing Library Preparation. Nietsch, R., Haas, J., Lai, A., Oehler, D., Mester, S., Frese, K. S., Sedaghat-Hamedani, F., Kayvanpour, E., Keller, A. & Meder, B. Genomics, proteomics & bioinformatics, (2016).  

Analysis with the Exome Array Identifies Multiple New Independent Variants in Lipid Loci. Kanoni, S., Masca, N. G., Stirrups, K. E., Varga, T. V., Warren, H. R., Scott, R. A., Southam, L., Zhang, W., Yaghootkar, H., Muller-Nurasyid, M., Couto Alves, A., Strawbridge, R. J., Lataniotis, L., Hashim, N. A., Besse, C., Boland, A., Braund, P. S., Connell, J. M., Dominiczak, A., Farmaki, A. E. et al. Human molecular genetics, (2016).  

Surgical Treatment of Mediastinitis with Omentoplasty in Ventricular Assist Device Patients: Report of Referral Center Experience. Pieri, M., Muller, M., Scandroglio, A. M., Pergantis, P., Kretzschmar, A., Kaufmann, F., Falk, V., Krabatsch, T., Arlt, G., Kukucka, M. & Potapov, E. ASAIO journal, (2016).  

Environmental Stressors and Cardio-Metabolic Disease: Part I-Epidemiologic Evidence Supporting a Role for Noise and Air Pollution and Effects of Mitigation Strategies. Munzel, T., Sorensen, M., Gori, T., Schmidt, F. P., Rao, X., Brook, J., Chen, L. C., Brook, R. D. & Rajagopalan, S. European heart journal, (2016).  

Environmental Stressors and Cardio-Metabolic Disease: Part Ii-Mechanistic Insights. Munzel, T., Sorensen, M., Gori, T., Schmidt, F. P., Rao, X., Brook, F. R., Chen, L. C., Brook, R. D. & Rajagopalan, S. European heart journal, (2016).  

Human Endomyocardial Biopsy Specimen-Derived Stromal Cells Modulate Angiotensin Ii-Induced Cardiac Remodeling. Miteva, K., Van Linthout, S., Pappritz, K., Muller, I., Spillmann, F., Haag, M., Stachelscheid, H., Ringe, J., Sittinger, M. & Tschope, C. Stem cells translational medicine, (2016).  

Weight Loss Partially Restores Glucose-Driven Betatrophin Response in Humans. Maurer, L., Brachs, S., Decker, A. M., Brachs, M., Leupelt, V., Jumpertz von Schwartzenberg, R., Ernert, A., Bobbert, T., Krude, H., Spranger, J. & Mai, K. The Journal of clinical endocrinology and metabolism, jc20161788, (2016).

Constitutive Gitr Activation Reduces Atherosclerosis by Promoting Regulatory Cd4+ T-Cell Responses. Meiler, S., Smeets, E., Winkels, H., Shami, A., Pascutti, F. M., Nolte, M. A., Beckers, L., Weber, C., Gerdes, N. & Lutgens, E. Arteriosclerosis, thrombosis, and vascular biology, (2016).   

The Cardiovascular Markers Copeptin and High-Sensitive C-Reactive Protein Decrease Following Specific Therapy for Primary Aldosteronism. Remde, H., Dietz, A., Emeny, R., Riester, A., Peters, A., de Las Heras Gala, T., Then, C., Seissler, J., Beuschlein, F., Reincke, M. & Quinkler, M. Journal of hypertension, (2016).  

Mesenchymal Stem Cells Attenuate Inflammatory Processes in the Heart and Lung Via Inhibition of Tnf Signaling. Martire, A., Bedada, F. B., Uchida, S., Poling, J., Kruger, M., Warnecke, H., Richter, M., Kubin, T., Herold, S. & Braun, T. Basic research in cardiology 111, 54, (2016).  

Perfusion Cardiovascular Magnetic Resonance and Fractional Flow Reserve in Patients with Angiographic Multi-Vessel Coronary Artery Disease. Hussain, S. T., Chiribiri, A., Morton, G., Bettencourt, N., Schuster, A., Paul, M., Perera, D. & Nagel, E. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 18, 44, (2016).  

Oral Supplementation with L-Homoarginine in Young Volunteers. Atzler, D., Schonhoff, M., Cordts, K., Ortland, I., Hoppe, J., Hummel, F. C., Gerloff, C., Jaehde, U., Jagodzinski, A., Boger, R. H., Choe, C. U. & Schwedhelm, E. British journal of clinical pharmacology, (2016).  

The Use of Echocardiography Post Heart Transplantation. Dandel, M. & Hetzer, R. Expert review of cardiovascular therapy, (2016).  

Altered Relation of the Renin-Aldosterone System and Vasoactive Peptides in Type 2 Diabetes: The Kora F4 Study. Then, C., Rottenkolber, M., Lechner, A., Meisinger, C., Heier, M., Koenig, W., Peters, A., Rathmann, W., Bidlingmaier, M., Reincke, M. & Seissler, J. Atherosclerosis, (2016).  

On the Use of Harrell’s C for Clinical Risk Prediction Via Random Survival Forests. Schmid, M., Wright, M. N. & Ziegler, A. Expert Systems with Applications, (2016).  

A Novel De Novo Tbx5 Mutation in a Patient with Holt–Oram Syndrome Leading to a Dramatically Reduced Biological Function. Dressen, M., Lahm, H., Lahm, A., Wolf, K., Doppler, S., Deutsch, M.-A., Cleuziou, J., Pabst von Ohain, J., Schon, P., Ewert, P., Malcic, I., Lange, R. & Krane, M. Molecular Genetics & Genomic Medicine (2016).

Changes of Myocardial Gene Expression and Protein Composition in Patients with Dilated Cardiomyopathy after Immunoadsorption with Subsequent Immunoglobulin Substitution. Ameling, S., Bhardwaj, G., Hammer, E., Beug, D., Steil, L., Reinke, Y., Weitmann, K., Grube, M., Trimpert, C., Klingel, K., Kandolf, R., Hoffmann, W., Nauck, M., Dorr, M., Empen, K., Felix, S. B. & Volker, U. Basic research in cardiology 111, 53, (2016).  

A Genome-Wide Association Meta-Analysis on Apolipoprotein a-Iv Concentrations. Lamina, C., Friedel, S., Coassin, S., Rueedi, R., Yousri, N. A., Seppala, I., Gieger, C., Schonherr, S., Forer, L., Erhart, G., Kollerits, B., Marques-Vidal, P., Ried, J., Waeber, G., Bergmann, S., Dahnhardt, D., Stockl, A., Kiechl, S., Raitakari, O. T., Kahonen, M. et al. Human molecular genetics, (2016).

J-Wave Syndromes Expert Consensus Conference Report: Emerging Concepts and Gaps in Knowledge: Endorsed by the Asia Pacific Heart Rhythm Society (Aphrs), the European Heart Rhythm Association (Ehra), the Heart Rhythm Society (Hrs), and the Latin American Society of Cardiac Pacing and Electrophysiology (Sociedad Latinoamericana De Estimulacion Cardiaca Y Electrofisiologia [Solaece]). Antzelevitch, C., Yan, G. X., Ackerman, M. J., Borggrefe, M., Corrado, D., Guo, J., Gussak, I., Hasdemir, C., Horie, M., Huikuri, H., Ma, C., Morita, H., Nam, G. B., Sacher, F., Shimizu, W., Viskin, S. & Wilde, A. A. Heart rhythm : the official journal of the Heart Rhythm Society, (2016).

Free-Breathing Sparse Sampling Cine Mr Imaging with Iterative Reconstruction for the Assessment of Left Ventricular Function and Mass at 3.0 T. Sudarski, S., Henzler, T., Haubenreisser, H., Dosch, C., Zenge, M. O., Schmidt, M., Nadar, M. S., Borggrefe, M., Schoenberg, S. O. & Papavassiliu, T. Radiology, 151002, (2016).    

The Nadph Oxidase Nox2 Mediates Vitamin D-Induced Vascular Regeneration in Male Mice. Leisegang, M. S., Babelova, A., Sze Ka Wong, M., Helfinger, V., Weissmann, N., Brandes, R. P. & Schroder, K. Endocrinology, en20161257, (2016).  

Mutant Desmin Substantially Perturbs Mitochondrial Morphology, Function and Maintenance in Skeletal Muscle Tissue. Winter, L., Wittig, I., Peeva, V., Eggers, B., Heidler, J., Chevessier, F., Kley, R. A., Barkovits, K., Strecker, V., Berwanger, C., Herrmann, H., Marcus, K., Kornblum, C., Kunz, W. S., Schroder, R. & Clemen, C. S. Acta neuropathologica, (2016).  

Wars2 Is a Determinant of Angiogenesis. Wang, M., Sips, P., Khin, E., Rotival, M., Sun, X., Ahmed, R., Widjaja, A. A., Schafer, S., Yusoff, P., Choksi, P. K., Ko, N. S., Singh, M. K., Epstein, D., Guan, Y., Houstek, J., Mracek, T., Nuskova, H., Mikell, B., Tan, J., Pesce, F. et al. Nature communications 7, 12061, (2016).  

T1 Mapping in Characterizing Myocardial Disease: A Comprehensive Review. Puntmann, V. O., Peker, E., Chandrashekhar, Y. & Nagel, E. Circulation research 119, 277-299, (2016).  

The Architecture of Neutrophil Extracellular Traps Investigated by Atomic Force Microscopy. Pires, R. H., Felix, S. B. & Delcea, M. Nanoscale, (2016).  

S100a6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling. Lerchenmuller, C., Heissenberg, J., Damilano, F., Bezzeridis, V. J., Kramer, I., Bochaton-Piallat, M. L., Hirschberg, K., Busch, M., Katus, H. A., Peppel, K., Rosenzweig, A., Busch, H., Boerries, M. & Most, P. Arteriosclerosis, thrombosis, and vascular biology, (2016).  

Catheter Ablation in Patients with Persistent Atrial Fibrillation. Kirchhof, P. & Calkins, H. European heart journal, (2016).  

Interventional Cardiology: Polymer-Free Drug-Eluting Stents - a Safe and Effective Option for Acs. Harada, Y. & Kastrati, A. Nature reviews. Cardiology, (2016).  

The Transcriptomes of Novel Marmoset Monkey Embryonic Stem Cell Lines Reflect Distinct Genomic Features. Debowski, K., Drummer, C., Lentes, J., Cors, M., Dressel, R., Lingner, T., Salinas-Riester, G., Fuchs, S., Sasaki, E. & Behr, R. Scientific reports 6, 29122, (2016).  

Echocardiographic Assessment of the Right Ventricle: Impact of the Distinctly Load Dependency of Its Size, Geometry and Performance. Dandel, M. & Hetzer, R. International journal of cardiology, (2016).  

The Predictive Value of Different Equations for Estimation of Glomerular Filtration Rate in Patients with Coronary Artery Disease – Results from the Atherogene Study. Waldeyer, C., Karakas, M., Scheurle, C., Ojeda, F., Schnabel, R. B., Zeller, T., Zengin, E., Westermann, D., Schrage, B., Bickel, C., Rupprecht, H. J., Lackner, K., Blankenberg, S., Seiffert, M. & Sinning, C. International journal of cardiology, (2016).  

Screening and Validation of Lncrnas and Circrnas as Mirna Sponges. Militello, G., Weirick, T., John, D., Doring, C., Dimmeler, S. & Uchida, S. Briefings in bioinformatics, (2016).

Preprocedural but Not Periprocedural High-Sensitive Troponin T (Hstnt) Levels Predict Outcome in Patients Undergoing Transcatheter Aortic Valve Implantation (Tavi). Kohler, W. M., Freitag-Wolf, S., Lambers, M., Lutz, M., Niemann, P. M., Petzina, R., Lutter, G., Bramlage, P., Frey, N. & Frank, D. Cardiovascular therapeutics, (2016).

Plasma Fibroblast Growth Factor 23: Clinical Correlates and Association with Cardiovascular Disease and Mortality in the Framingham Heart Study. Haring, R., Enserro, D., Xanthakis, V., Mitchell, G. F., Benjamin, E. J., Hamburg, N. M., Sullivan, L., Nauck, M., Wallaschofski, H. & Ramachandran, V. S. Journal of the American Heart Association, (2016).

Further Insights in the Most Common Scn5a Mutation Causing Overlapping Phenotype of Long Qt Syndrome, Brugada Syndrome, and Conduction Defect. Veltmann, C., Barajas-Martinez, H., Wolpert, C., Borggrefe, M., Schimpf, R., Pfeiffer, R., Caceres, G., Burashnikov, E., Antzelevitch, C. & Hu, D. Journal of the American Heart Association 5, (2016).

Cardiac Amyloid Load: A Prognostic and Predictive Biomarker in Patients with Light-Chain Amyloidosis. Kristen, A. V., Brokbals, E., Aus dem Siepen, F., Bauer, R., Hein, S., Aurich, M., Riffel, J., Behrens, H. M., Kruger, S., Schirmacher, P., Katus, H. A. & Rocken, C. Journal of the American College of Cardiology 68, 13-24, (2016).

Current and Cumulative Night Shift Work and Subclinical Atherosclerosis: Results of the Gutenberg Health Study. Jankowiak, S., Backe, E., Liebers, F., Schulz, A., Hegewald, J., Garthus-Niegel, S., Nubling, M., Blankenberg, S., Pfeiffer, N., Lackner, K. J., Beutel, M., Blettner, M., Munzel, T., Wild, P. S., Seidler, A., Letzel, S. & Latza, U. International archives of occupational and environmental health, (2016).

Five-Year Follow-up of Polymer-Free Sirolimus- and Probucol-Eluting Stents Versus New Generation Zotarolimus-Eluting Stents in Patients Presenting with St-Elevation Myocardial Infarction. Colleran, R., Kufner, S., Harada, Y., Giacoppo, D., Cassese, S., Repp, J., Wiebe, J., Lohaus, R., Lahmann, A., Schneider, S., Ibrahim, T., Laugwitz, K. L., Kastrati, A., Byrne, R. A., Intracoronary, S., Angiographic Results: Test Efficacy of, S. & Probucol-Eluting Versus Zotarolimus-Eluting Stents, I. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, (2016).

Culprit Lesion Location and Outcome in Patients with Cardiogenic Shock Complicating Myocardial Infarction: A Substudy of the Iabp-Shock Ii-Trial. Fuernau, G., Fengler, K., Desch, S., Eitel, I., Neumann, F. J., Olbrich, H. G., de Waha, A., de Waha, S., Richardt, G., Hennersdorf, M., Empen, K., Hambrecht, R., Jung, C., Bohm, M., Poss, J., Strasser, R. H., Schneider, S., Ouarrak, T., Schuler, G., Werdan, K. et al. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).

Liver and Cholestatic Parameters as Prognostic Biomarkers of in-Hospital Mace in Patients with Stemi. Huseynov, A., Baumann, S., Becher, T., Koepp, J., Lang, S., Jabbour, C., Behnes, M., Borggrefe, M. & Akin, I. European journal of clinical investigation, (2016).

Zooming in on Micrornas for Refining Cardiovascular Risk Prediction in Secondary Prevention. Santovito, D. & Weber, C. European heart journal, (2016).

Measurement of Extracellular Volume and Transit Time Heterogeneity Using Contrast-Enhanced Myocardial Perfusion Mri in Patients after Acute Myocardial Infarction. Kunze, K. P., Rischpler, C., Hayes, C., Ibrahim, T., Laugwitz, K. L., Haase, A., Schwaiger, M. & Nekolla, S. G. Magnetic resonance in medicine, (2016).

Effect of Rosuvastatin or Its Combination with Omega-3 Fatty Acids on Circulating Cd34+ Progenitor Cells and on Endothelial Colony Formation in Patients with Mixed Dyslipidaemia. Chantzichristos, V. G., Agouridis, A. P., Moutzouri, E., Stellos, K., Elisaf, M. S. & Tselepis, A. D. Atherosclerosis, (2016).

Stimulators of the Soluble Guanylyl Cyclase: Promising Functional Insights from Rare Coding Atherosclerosis-Related Gucy1a3 Variants. Wobst, J., von Ameln, S., Wolf, B., Wierer, M., Dang, T. A., Sager, H. B., Tennstedt, S., Hengstenberg, C., Koesling, D., Friebe, A., Braun, S. L., Erdmann, J., Schunkert, H. & Kessler, T. Basic research in cardiology 111, 51, (2016).

Cardiac Involvement in Myotonic Dystrophy Type 2 Patients with Preserved Ejection Fraction: Detection by Cardiovascular Magnetic Resonance. Schmacht, L., Traber, J., Grieben, U., Utz, W., Dieringer, M. A., Kellman, P., Blaszczyk, E., von Knobelsdorff-Brenkenhoff, F., Spuler, S. & Schulz-Menger, J. Circulation. Cardiovascular imaging 9, (2016).

Nitroglycerin Induces DNA Damage and Vascular Cell Death in the Setting of Nitrate Tolerance. Mikhed, Y., Fahrer, J., Oelze, M., Kroller-Schon, S., Steven, S., Welschof, P., Zinssius, E., Stamm, P., Kashani, F., Roohani, S., Kress, J. M., Ullmann, E., Tran, L. P., Schulz, E., Epe, B., Kaina, B., Munzel, T. & Daiber, A. Basic research in cardiology 111, 52, (2016).

Complying with the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations. Daugherty, A., Hegele, R. A., Mackman, N., Rader, D. J., Schmidt, A. M. & Weber, C. Arteriosclerosis, thrombosis, and vascular biology 36, 1303-1304, (2016).

Smoking Fruit Flies – Impact of Cigarette Smoke Exposure on the Airway Epithelium of Drosophila Melanogaster. Bhandari, A., Roeder, T. & Erdmann, J. Pneumologie, (2016).  

[Assessment of Risk of Sudden Cardiac Death in Patients with Hypertrophic Cardiomyopathy]. Attanasio, P., Blaschke, F., Pieske, B., Tschope, C. & Haverkamp, W. Deutsche medizinische Wochenschrift 141, 1035-1039, (2016).


Renal Denervation for Treatment of Ventricular Arrhythmias: Data from an International Multicenter Registry. Ukena, C., Mahfoud, F., Ewen, S., Bollmann, A., Hindricks, G., Hoffmann, B. A., Linz, D., Musat, D., Pavlicek, V., Scholz, E., Thomas, D., Willems, S., Bohm, M. & Steinberg, J. S. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).

Extending Laboratory Automation to the Wards: Effect of an Innovative Pneumatic Tube System on Diagnostic Samples and Transport Time. Suchsland, J., Winter, T., Greiser, A., Streichert, T., Otto, B., Mayerle, J., Runge, S., Kallner, A., Nauck, M. & Petersmann, A. Clinical chemistry and laboratory medicine, (2016).

Circulating Micrornas Strongly Predict Cardiovascular Death in Patients with Coronary Artery Disease-Results from the Large Atherogene Study. Karakas, M., Schulte, C., Appelbaum, S., Ojeda, F., Lackner, K. J., Munzel, T., Schnabel, R. B., Blankenberg, S. & Zeller, T. European heart journal, (2016).

Characteristics and Long-Term Outcome of Right Ventricular Involvement in Takotsubo Cardiomyopathy. Becher, T., El-Battrawy, I., Baumann, S., Fastner, C., Behnes, M., Lossnitzer, D., Elmas, E., Hoffmann, U., Papavassiliu, T., Kuschyk, J., Dosch, C., Roger, S., Hillenbrand, D., Schramm, K., Borggrefe, M. & Akin, I. International journal of cardiology 220, 371-375, (2016).

Effect of Escitalopram on All-Cause Mortality and Hospitalization in Patients with Heart Failure and Depression: The Mood-Hf Randomized Clinical Trial. Angermann, C. E., Gelbrich, G., Stork, S., Gunold, H., Edelmann, F., Wachter, R., Schunkert, H., Graf, T., Kindermann, I., Haass, M., Blankenberg, S., Pankuweit, S., Prettin, C., Gottwik, M., Bohm, M., Faller, H., Deckert, J., Ertl, G., Investigators, M.-H. S. & Committee, M. Jama 315, 2683-2693, (2016).

[Therapy Forms for Advanced Heart Failure]. Kopp Fernandes, L., Hummel, M., Knosalla, C. & Schonrath, F. Der Kardiologe, (2016).

Association of Novel Metrics of Particulate Matter with Vascular Markers of Inflammation and Coagulation in Susceptible Populations -Results from a Panel Study. Ruckerl, R., Schneider, A., Hampel, R., Breitner, S., Cyrys, J., Kraus, U., Gu, J., Soentgen, J., Koenig, W. & Peters, A. Environmental research 150, 337-347, (2016).

Why the Study of the Effects of Biological Sex Is Important. Commentary. Kararigas, G., Seeland, U., Barcena de Arellano, M. L., Dworatzek, E. & Regitz-Zagrosek, V. Annali dell'Istituto superiore di sanita 52, 149-150, (2016).

Thomas Willis Lecture: Is Translational Stroke Research Broken, and If So, How Can We Fix It? Dirnagl, U. Stroke; a journal of cerebral circulation, (2016). 

Drug-Eluting Balloons or Stents for Bare-Metal Stent Restenosis. Wiebe, J., Colleran, R. & Kastrati, A. JACC. Cardiovascular interventions 9, 1256-1258, (2016).

Mechanosensitive Gq/11 -Protein Coupled Receptors Mediate Myogenic Vasoconstriction. Mederos, Y. S. M., Storch, U. & Gudermann, T. Microcirculation, (2016).

Myocardial Effective Transverse Relaxation Time T2* Correlates with Left Ventricular Wall Thickness: A 7.0 T Mri Study. Huelnhagen, T., Hezel, F., Serradas Duarte, T., Pohlmann, A., Oezerdem, C., Flemming, B., Seeliger, E., Prothmann, M., Schulz-Menger, J. & Niendorf, T. Magnetic resonance in medicine, (2016).

Novel Therapeutic Strategies Targeting Fibroblasts and Fibrosis in Heart Disease. Gourdie, R. G., Dimmeler, S. & Kohl, P. Nature reviews. Drug discovery, (2016).

Comparison and Outcome Analysis of Patients with Apical and Non-Apical Takotsubo Cardiomyopathy. El-Battrawy, I., Behnes, M., Ansari, U., Hillenbrand, D., Haghi, D., Hoffmann, U., Papavassiliu, T., Elmas, E., Fastner, C., Becher, T., Baumann, S., Dosch, C., Heggemann, F., Kuschyk, J., Borggrefe, M. & Akin, I. QJM : monthly journal of the Association of Physicians, (2016).

Rapid Molecular Diagnosis of Infective Aortic Valve Endocarditis Caused by Coxiella Burnetti. Kumpf, O., Dohmen, P., Ertmer, M., Knebel, F., Wiessner, A., Kikhney, J., Moter, A. & Treskatsch, S. Infection, (2016).

Exogenous Administration of Recombinant Mif at Physiological Concentrations Failed to Attenuate Infarct Size in a Langendorff Perfused Isolated Mouse Heart Model. Rossello, X., Burke, N., Stoppe, C., Bernhagen, J., Davidson, S. M. & Yellon, D. M. Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, (2016).

Large-Scale Exome-Wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. Tajuddin, S. M., Schick, U. M., Eicher, J. D., Chami, N., Giri, A., Brody, J. A., Hill, W. D., Kacprowski, T., Li, J., Lyytikainen, L. P., Manichaikul, A., Mihailov, E., O'Donoghue, M. L., Pankratz, N., Pazoki, R., Polfus, L. M., Smith, A. V., Schurmann, C., Vacchi-Suzzi, C., Waterworth, D. M. et al. American journal of human genetics, (2016).

Frequency of Miscarriage/Stillbirth and Terminations of Pregnancy among Women with Congenital Heart Disease in Germany, Hungary and Japan. Koerten, M. A., Niwa, K., Szatmari, A., Hajnalka, B., Ruzsa, Z., Nagdyman, N., Niggemeyer, E., Peters, B., Schneider, K. M., Kuschel, B., Mizuno, Y., Berger, F., Kaemmerer, H. & Bauer, U. M. Circulation journal : official journal of the Japanese Circulation Society, (2016).

Platelet-Related Variants Identified by Exomechip Meta-Analysis in 157,293 Individuals. Eicher, J. D., Chami, N., Kacprowski, T., Nomura, A., Chen, M. H., Yanek, L. R., Tajuddin, S. M., Schick, U. M., Slater, A. J., Pankratz, N., Polfus, L., Schurmann, C., Giri, A., Brody, J. A., Lange, L. A., Manichaikul, A., Hill, W. D., Pazoki, R., Elliot, P., Evangelou, E. et al. American journal of human genetics, (2016).

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. Chami, N., Chen, M. H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. et al. American journal of human genetics, (2016).

Lipoprotein-Associated Phospholipase A2 Activity Is a Marker of Risk but Not a Useful Target for Treatment in Patients with Stable Coronary Heart Disease. Wallentin, L., Held, C., Armstrong, P. W., Cannon, C. P., Davies, R. Y., Granger, C. B., Hagstrom, E., Harrington, R. A., Hochman, J. S., Koenig, W., Krug-Gourley, S., Mohler, E. R., 3rd, Siegbahn, A., Tarka, E., Steg, P. G., Stewart, R. A., Weiss, R., Ostlund, O., White, H. D. & Investigators, S. Journal of the American Heart Association 5, (2016).

Characterization, Mapping and Ablation of Complex Atrial Tachycardia: Initial Experience with a Novel Method of Ultra High-Density 3d Mapping. Schaeffer, B., Hoffmann, B. A., Meyer, C., Akbulak, R. O., Moser, J., Jularic, M., Eickholt, C., Nuhrich, J. M., Kuklik, P. & Willems, S. Journal of cardiovascular electrophysiology, (2016).

Bioresorbable Vascular Scaffolds in a Real-World Patient Population-Results from a Mid-Term Angiographic Follow-Up. Saad, M., Abdin, A., Thiele, H., Desch, S., Ibrahimi, P., Wikstroem, G., Hoeher, M. & Henein, M. Journal of interventional cardiology, (2016).

Influence of Distance to Scene on Time to Thrombolysis in a Specialized Stroke Ambulance. Koch, P. M., Kunz, A., Ebinger, M., Geisler, F., Rozanski, M., Waldschmidt, C., Weber, J. E., Wendt, M., Winter, B., Zieschang, K., Bollweg, K., Kaczmarek, S., Endres, M. & Audebert, H. J. Stroke; a journal of cerebral circulation, (2016).

The Embryological Basis of Subclinical Hypertrophic Cardiomyopathy. Captur, G., Ho, C. Y., Schlossarek, S., Kerwin, J., Mirabel, M., Wilson, R., Rosmini, S., Obianyo, C., Reant, P., Bassett, P., Cook, A. C., Lindsay, S., McKenna, W. J., Mills, K., Elliott, P. M., Mohun, T. J., Carrier, L. & Moon, J. C. Scientific reports 6, 27714, (2016).

Cardiac Troponin I: A Valuable Biomarker Indicating the Cardiac Involvement in Fabry Disease. Tanislav, C., Guenduez, D., Liebetrau, C., Giese, A. K., Eichler, S., Sieweke, N., Speth, M., Bauer, T., Hamm, C. & Rolfs, A. PloS one 11, e0157640, (2016).

Be More Sensitive, Please - Using Cardiac Troponin Assays for Diagnosing Ami. Neumann, J. T., Blankenberg, S. & Westermann, D. Heart, (2016).

Eisenmenger Syndrome and Long-Term Survival in Patients with Down Syndrome and Congenital Heart Disease. Korten, M. A., Helm, P. C., Abdul-Khaliq, H., Baumgartner, H., Kececioglu, D., Schlensak, C., Bauer, U. M., Diller, G. P. & Competence Network for Congenital Heart Defects, I. Heart, (2016).

A Randomized, Parallel Group, Double-Blind Study of Ticagrelor Compared with Aspirin for Prevention of Vascular Events in Patients Undergoing Coronary Artery Bypass Graft Operation: Rationale and Design of the Ticagrelor in Cabg (Ticab-) Trial: An Investigator-Initiated Trial. De Waha, A., Sandner, S., von Scheidt, M., Boening, A., Koch-Buettner, K., Hammel, D., Hambrecht, R., Danner, B. C., Schondube, F. A., Goerlach, G., Fischlein, T., Schmoeckel, M., Oberhoffer, M., Schulz, R., Walther, T., Ziegelhoffer, T., Knosalla, C., Schonrath, F., Beyersdorf, F., Siepe, M. et al. American heart journal, (2016).

Long-Term Outcome of Patients with Virus-Negative Chronic Myocarditis or Inflammatory Cardiomyopathy after Immunosuppressive Therapy. Escher, F., Kuhl, U., Lassner, D., Poller, W., Westermann, D., Pieske, B., Tschope, C. & Schultheiss, H. P. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).

Subtype-Specific Promoter-Driven Action Potential Imaging for Precise Disease Modelling and Drug Testing in Hipsc-Derived Cardiomyocytes. Chen, Z., Xian, W., Bellin, M., Dorn, T., Tian, Q., Goedel, A., Dreizehnter, L., Schneider, C. M., Ward-van Oostwaard, D., Ng, J. K., Hinkel, R., Pane, L. S., Mummery, C. L., Lipp, P., Moretti, A., Laugwitz, K. L. & Sinnecker, D. European heart journal, (2016).

Proatherosclerotic Effect of the Alpha1-Subunit of Soluble Guanylyl Cyclase by Promoting Smooth Muscle Phenotypic Switching. Segura-Puimedon, M., Mergia, E., Al-Hasani, J., Aherrahrou, R., Stoelting, S., Kremer, F., Freyer, J., Kosling, D., Erdmann, J., Schunkert, H., de Wit, C. & Aherrahrou, Z. The American journal of pathology, (2016).

Radiation Exposure and Contrast Agent Use Related to Radial Versus Femoral Arterial Access During Percutaneous Coronary Intervention (Pci) - Results of the Ferari Study. Becher, T., Behnes, M., Unsal, M., Baumann, S., El-Battrawy, I., Fastner, C., Kuschyk, J., Papavassiliu, T., Hoffmann, U., Mashayekhi, K., Borggrefe, M. & Akin, I. Cardiovascular Revascularization Medicine, (2016).

Patients’ Knowledge About Symptoms and Adequate Behaviour During Acute Myocardial Infarction and Its Impact on Delay Time. Albarqouni, L., Smenes, K., Meinertz, T., Schunkert, H., Fang, X., Ronel, J. & Ladwig, K. H. PEC Patient Education & Counseling, (2016).

Differential Transcriptional Regulation of Hypoxia-Inducible Factor-1alpha by Arsenite under Normoxia and Hypoxia: Involvement of Nrf2. Al Taleb, Z., Petry, A., Chi, T. F., Mennerich, D., Gorlach, A., Dimova, E. Y. & Kietzmann, T. Journal of molecular medicine, (2016).

[Lipid-Lowering Therapy in Europe and the United States - Treat to Target or Fire and Forget?]. Pfetsch, V., Sanin, V. & Koenig, W. Deutsche medizinische Wochenschrift 141, 857-862, (2016).

Diagnosis and Treatment Algorithm for Blood Flow Obstructions in Patients with Left Ventricular Assist Device. Scandroglio, A. M., Kaufmann, F., Pieri, M., Kretzschmar, A., Muller, M., Pergantis, P., Dreysse, S., Falk, V., Krabatsch, T. & Potapov, E. V. Journal of the American College of Cardiology 67, 2758-2768, (2016). 

Management of Arrhythmias in Patients with Takotsubo Cardiomyopathy: Is the Implantation of Permanent Devices Necessary? Stiermaier, T., Rommel, K. P., Eitel, C., Moller, C., Graf, T., Desch, S., Thiele, H. & Eitel, I. Heart rhythm : the official journal of the Heart Rhythm Society, (2016).

Endophenotype Network Models: Common Core of Complex Diseases. Ghiassian, S. D., Menche, J., Chasman, D. I., Giulianini, F., Wang, R., Ricchiuto, P., Aikawa, M., Iwata, H., Muller, C., Zeller, T., Sharma, A., Wild, P., Lackner, K., Singh, S., Ridker, P. M., Blankenberg, S., Barabasi, A. L. & Loscalzo, J. Scientific reports 6, 27414, (2016).

The Cytosolic Nadph Oxidase Subunit Noxo1 Promotes an Endothelial Stalk Cell Phenotype. Brandes, R. P., Harenkamp, S., Schurmann, C., Josipovic, I., Rashid, B., Rezende, F., Lowe, O., Moll, F., Epah, J., Eresch, J., Nayak, A., Kopaliani, I., Penski, C., Mittelbronn, M., Weissmann, N. & Schroder, K. Arteriosclerosis, thrombosis, and vascular biology, (2016).

Regional Variability of Lifestyle Factors and Hypertension with Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus: The Population-Based Kora-F4 and Ship-Trend Studies in Germany. Stockl, D., Ruckert-Eheberg, I. M., Heier, M., Peters, A., Schipf, S., Krabbe, C., Volzke, H., Tamayo, T., Rathmann, W. & Meisinger, C. PloS one 11, e0156736, (2016).

Ticagrelor Versus Prasugrel in Patients with High on-Clopidogrel Treatment Platelet Reactivity after Pci: The Isar-Adapt-Pf Study. Bernlochner, I., Mayer, K., Orban, M., Morath, T., Jaitner, J., Rossner, L., Gross, L., Laugwitz, K. L., Kastrati, A. & Sibbing, D. Platelets, 1-9, (2016).

The Cytoprotective Capacity of Processed Human Cardiac Extracellular Matrix. Kappler, B., Anic, P., Becker, M., Bader, A., Klose, K., Klein, O., Oberwallner, B., Choi, Y. H., Falk, V. & Stamm, C. Journal of materials science. Materials in medicine 27, 120, (2016).

Therapeutic Hypothermia Impacts Leukocyte Kinetics after Cardiac Arrest. Dufner, M. C., Andre, F., Stiepak, J., Zelniker, T., Chorianopoulos, E., Preusch, M., Katus, H. A. & Leuschner, F. Cardiovascular diagnosis and therapy 6, 199-207, (2016).

Bioresorbable Vascular Scaffolds in Patients with Acute Myocardial Infarction: A New Step Forward to Optimized Reperfusion? Alfonso, F., Cuesta, J., Bastante, T., Rivero, F., Garcia-Guimaraes, M., Alvarado, T., Benedicto, A., Cortese, B., Byrne, R. & Kastrati, A. Journal of thoracic disease 8, E417-423, (2016).

Distilling Complexity to Advance Cardiac Tissue Engineering. Ogle, B. M., Bursac, N., Domian, I., Huang, N. F., Menasche, P., Murry, C. E., Pruitt, B., Radisic, M., Wu, J. C., Wu, S. M., Zhang, J., Zimmermann, W.-H. & Vunjak-Novakovic, G. Science translational medicine 8, (2016).

Left Ventricular Long Axis Strain: A New Prognosticator in Non-Ischemic Dilated Cardiomyopathy? Riffel, J. H., Keller, M. G. P., Rost, F., Arenja, N., Andre, F., aus dem Siepen, F., Fritz, T., Ehlermann, P., Taeger, T., Frankenstein, L., Meder, B., Katus, H. A. & Buss, S. J. Journal of Cardiovascular Magnetic Resonance 18, (2016).

Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus Combat as Best Approach for Microarray Transcriptome Data. Muller, C., Schillert, A., Rothemeier, C., Tregouet, D. A., Proust, C., Binder, H., Pfeiffer, N., Beutel, M., Lackner, K. J., Schnabel, R. B., Tiret, L., Wild, P. S., Blankenberg, S., Zeller, T. & Ziegler, A. PloS one, (2016).

Differentiation of Functional Endothelial Cells from Human Induced Pluripotent Stem Cells: A Novel, Highly Efficient and Cost Effective Method. Liu, X., Qi, J., Xu, X., Zeisberg, M., Guan, K. & Zeisberg, E. M. Differentiation, (2016).

Nuclear Translocation of the Cardiac L-Type Calcium Channel C-Terminus Is Regulated by Sex and 17β-Estradiol. Mahmoodzadeh, S., Haase, H., Sporbert, A., Rharass, T., Panakova, D. & Morano, I. JMCC, (2016).

Endothelial Rage Exacerbates Acute Postischaemic Cardiac Inflammation. Ziegler, T., Horstkotte, M., Lange, P., Ng, J., Bongiovanni, D., Hinkel, R., Laugwitz, K. L., Sperandio, M., Horstkotte, J. & Kupatt, C. Thrombosis and haemostasis, (2016).

[Computed Tomography in Patients with Chronic Stable Angina : Fractional Flow Reserve Measurement]. Renker, M., Schoepf, U. J., Becher, T., Krampulz, N., Kim, W., Rolf, A., Mollmann, H., Hamm, C. W., Henzler, T., Borggrefe, M., Akin, I. & Baumann, S. Herz, (2016).

Omentin-1 and Risk of Myocardial Infarction and Stroke: Results from the Epic-Potsdam Cohort Study. Menzel, J., di Giuseppe, R., Biemann, R., Wittenbecher, C., Aleksandrova, K., Pischon, T., Fritsche, A., Schulze, M. B., Boeing, H., Isermann, B. & Weikert, C. Atherosclerosis, (2016).

Galectin-3 Binding Protein Plasma Levels Are Associated with Long-Term Mortality in Coronary Artery Disease Independent of Plaque Morphology. Gleissner, C. A., Erbel, C., Linden, F., Domschke, G., Akhavanpoor, M., Doesch, A. O., Buss, S. J., Giannitsis, E., Katus, H. A. & Korosoglou, G. Atherosclerosis, (2016).

Surgical Experience and Long-Term Results of Baroreflex Activation Therapy for Heart Failure with Reduced Ejection Fraction. Weaver, F. A., Abraham, W. T., Little, W. C., Butter, C., Ducharme, A., Halbach, M., Klug, D., Lovett, E. G., Madershahian, N., Muller-Ehmsen, J., Schafer, J. E., Senni, M., Swarup, V., Wachter, R. & Zile, M. R. Seminars in Thoracic and Cardiovascular Surgery, (2016).

A Genomic Approach to Therapeutic Target Validation Identifies a Glucose-Lowering Glp1r Variant Protective for Coronary Heart Disease. Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. et al. Science translational medicine 8, 341ra376, (2016).

Cardiomyocyte-Derived Cxcl12 Is Not Involved in Cardiogenesis but Plays a Crucial Role in Myocardial Infarction. Muhlstedt, S., Ghadge, S. K., Duchene, J., Qadri, F., Jarve, A., Vilianovich, L., Popova, E., Pohlmann, A., Niendorf, T., Boye, P., Ozcelik, C. & Bader, M. Journal of molecular medicine, (2016).

Heart Failure Epidemiology 2000-2013: Insights from the German Federal Health Monitoring System. Christ, M., Stork, S., Dorr, M., Heppner, H. J., Muller, C., Wachter, R., Riemer, U. & Trend, H. F. G. P. European journal of heart failure, (2016).

Stent Polymers: Do They Make a Difference? Rizas, K. D. & Mehilli, J. Circulation. Cardiovascular interventions 9, (2016).

The Prevalence and Significance of the Early Repolarization Pattern in Sudden Arrhythmic Death Syndrome Families. Mellor, G., Nelson, C. P., Robb, C., Raju, H., Wijeyeratne, Y., Hengstenberg, C., Reinhard, W., Papadakis, M., Sharma, S., Samani, N. J. & Behr, E. R. Circulation. Arrhythmia and electrophysiology 9, (2016).

[Physical Training in Cardiology – the Intensity Is Crucial]. Halle, M. & Hambrecht, R. Der Kardiologe 10, 170-175, (2016).

Anp System Activity Predicts Variability of Fat Mass Reduction and Insulin Sensitivity During Weight Loss. Brachs, M., Wiegand, S., Leupelt, V., Ernert, A., Kintscher, U., Jumpertz von Schwarzenberg, R., Decker, A. M., Bobbert, T., Hubner, N., Chen, W., Krude, H., Spranger, J. & Mai, K. Metabolism: clinical and experimental 65, 935-943, (2016).

Electrophysiological Characterization of the Archaeal Transporter Ncx_Mj Using Solid Supported Membrane Technology. Barthmes, M., Liao, J., Jiang, Y., Bruggemann, A. & Wahl-Schott, C. The Journal of general physiology 147, 485-496, (2016).


Estradiol Modulates Myosin Regulatory Light Chain Phosphorylation and Contractility in Skeletal Muscle of Female Mice. Lai, S., Collins, B. C., Colson, B. A., Kararigas, G. & Lowe, D. A. American journal of physiology. Endocrinology and metabolism 310, E724-733, (2016).  

Bioresorbable Coronary Scaffold Thrombosis: Multicenter Comprehensive Analysis of Clinical Presentation, Mechanisms, and Predictors. Puricel, S., Cuculi, F., Weissner, M., Schmermund, A., Jamshidi, P., Nyffenegger, T., Binder, H., Eggebrecht, H., Munzel, T., Cook, S. & Gori, T. Journal of the American College of Cardiology 67, 921-931, (2016).  

Identification of Serum Metabolites Associated with Incident Hypertension in the European Prospective Investigation into Cancer and Nutrition-Potsdam Study. Dietrich, S., Floegel, A., Weikert, C., Pischon, T., Boeing, H. & Drogan, D. Hypertension, (2016).

Reduced Risk of Myocardial Infarct and Revascularization Following Coronary Artery Bypass Grafting Compared with Percutaneous Coronary Intervention in Patients with Chronic Kidney Disease. Charytan, D. M., Desai, M., Mathur, M., Stern, N. M., Brooks, M. M., Krzych, L. J., Schuler, G. C., Kaehler, J., Rodriguez-Granillo, A. M., Hueb, W., Reeves, B. C., Thiele, H., Rodriguez, A. E., Buszman, P. P., Buszman, P. E., Maurer, R. & Winkelmayer, W. C. Kidney international, (2016).

Proteomic Analysis of Short-Term Preload-Induced Eccentric Cardiac Hypertrophy. Mohamed, B. A., Asif, A. R., Schnelle, M., Qasim, M., Khadjeh, S., Lbik, D., Schott, P., Hasenfuss, G. & Toischer, K. Journal of translational medicine 14, 149, (2016).

Long-Term Excess Mortality in Takotsubo Syndrome: Is It Justified to Charge Takotsubo for the Excess Long-Term Mortality?: Reply. Stiermaier, T., Thiele, H. & Eitel, I. European journal of heart failure, (2016).

Stromal Cell-Derived Factor-1 Alpha Is Decreased in Women with Migraine with Aura. Liman, T. G., Neeb, L., Rosinski, J., Reuter, U. & Endres, M. Headache, (2016).

In Permanent Atrial Fibrillation Phosphodiesterase3 Reduces Force Responses to 5-Ht but Neither Pde3 nor Pde4 Influence Abolished 5-Ht-Evoked Arrhythmias. Berk, E., Christ, T., Schwarz, S., Ravens, U., Knaut, M. & Kaumann, A. J. British journal of pharmacology, (2016).

Clinical Correlates of Sex Hormones in Women: The Study of Health in Pomerania. Kische, H., Gross, S., Wallaschofski, H., Volzke, H., Dorr, M., Nauck, M. & Haring, R. Metabolism Clinical and Experimental, (2016).

The Time-of-Day of Myocardial Infarction Onset Affects Healing through Oscillations in Cardiac Neutrophil Recruitment. Schloss, M. J., Horckmans, M., Nitz, K., Duchene, J., Drechsler, M., Bidzhekov, K., Scheiermann, C., Weber, C., Soehnlein, O. & Steffens, S. EMBO Mol Med, (2016).

Regulation of Gap Junction Channels and Hemichannels by Phosphorylation and Redox Changes: A Revision. Pogoda, K., Kameritsch, P., Retamal, M. A. & Vega, J. L. BMC cell biology 17 Suppl 1, 11, (2016).

Processing and Transcriptome Expansion at the Mrna 3' End in Health and Disease: Finding the Right End. Ogorodnikov, A., Kargapolova, Y. & Danckwardt, S. Pflugers Archiv : European journal of physiology, (2016).

Multislice Computed Tomography-Guided Surgical Repair of Acquired Posterior Left Ventricular Aneurysms: Demonstration of Mitral Valve and Left Ventricular Reverse Remodelling. Solowjowa, N., Penkalla, A., Dandel, M., Novikov, A., Pasic, M., Weng, Y., Falk, V. & Knosalla, C. Interactive cardiovascular and thoracic surgery, (2016).

[Impact of Lipid Metabolism Parameters on the Development and Progression of Coronary Artery Disease : An Update]. Sinning, D., Leistner, D. M. & Landmesser, U. Herz, (2016).

Assessment of Ventriculo-Vascular Properties in Repaired Coarctation Using Cardiac Magnetic Resonance-Derived Aortic, Left Atrial and Left Ventricular Strain. Shang, Q., Sarikouch, S., Patel, S., Schuster, A., Steinmetz, M., Ou, P., Danford, D. A., Beerbaum, P. & Kutty, S. European radiology, (2016).

Inhibition of Cardiac Kir Current (Ik1) by Protein Kinase C Critically Depends on Pkcbeta and Kir2.2. Scherer, D., Seyler, C., Xynogalos, P., Scholz, E. P., Thomas, D., Backs, J., Andrassy, M., Volkers, M., Karle, C. A., Katus, H. A. & Zitron, E. PloS one 11, e0156181, (2016).

Prognostic Value of Gamma-Glutamyl Transferase in Patients with Diabetes Mellitus and Coronary Artery Disease. Ndrepepa, G., Colleran, R., Luttert, A., Braun, S., Cassese, S., Kufner, S., Hieber, J., Fusaro, M., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Clinical biochemistry, (2016).

Cd74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia. Przybyl, L., Haase, N., Golic, M., Rugor, J., Solano, M. E., Arck, P. C., Gauster, M., Huppertz, B., Emontzpohl, C., Stoppe, C., Bernhagen, J., Leng, L., Bucala, R., Schulz, H., Heuser, A., Weedon-Fekjaer, S., Johnsen, G. M., Peetz, D., Luft, F. C., Staff, A. C. et al. Circulation research, (2016).

Growth Differentiation Factor 15, Its 12-Month Relative Change, and Risk of Cardiovascular Events and Total Mortality in Patients with Stable Coronary Heart Disease: 10-Year Follow-up of the Karola Study. Dallmeier, D., Brenner, H., Mons, U., Rottbauer, W., Koenig, W. & Rothenbacher, D. Clinical chemistry, (2016).

Jmjd8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting with Pyruvate Kinase M2 in Endothelial Cells. Boeckel, J. N., Derlet, A., Glaser, S. F., Luczak, A., Lucas, T., Heumuller, A. W., Kruger, M., Zehendner, C. M., Kaluza, D., Doddaballapur, A., Ohtani, K., Treguer, K. & Dimmeler, S. Arteriosclerosis, thrombosis, and vascular biology, (2016).

Nt-Probnp and Diastolic Left Ventricular Function in Patients with Marfan Syndrome. Gehle, P., Robinson, P. N., Heinzel, F., Edelmann, F., Yigitbasi, M., Berger, F., Falk, V., Pieske, B. & Wellnhofer, E. IJC Heart & Vasculature, (2016).

Comparison of Cox Model Methods in a Low-Dimensional Setting with Few Events. Ojeda, F. M., Muller, C., Bornigen, D., Tregouet, D. A., Schillert, A., Heinig, M., Zeller, T. & Schnabel, R. B. Genomics, proteomics & bioinformatics, (2016).

Subclinical Impairment of Lung Function Is Related to Mild Cardiac Dysfunction and Manifest Heart Failure in the General Population. Baum, C., Ojeda, F. M., Wild, P. S., Rzayeva, N., Zeller, T., Sinning, C. R., Pfeiffer, N., Beutel, M., Blettner, M., Lackner, K., Blankenberg, S., Munzel, T., Rabe, K. F., Schnabel, R. B. & investigators, f. t. G. H. S. International journal of cardiology, (2016).

Cerebral Embolization During Transcatheter Aortic Valve Replacement: The Bravo-3 Mri Study. Van Belle, E., Hengstenberg, C., Lefevre, T., Kupatt, C., Debry, N., Husser, O., Pontana, F., Kuchcinski, G., Deliargyris, E. N., Mehran, R., Bernstein, D., Anthopoulos, P., Dangas, G. D. & Investigators, B.-M. S. Journal of the American College of Cardiology, (2016).

Mechanisms of Micrornas in Atherosclerosis. Schober, A. & Weber, C. Annual review of pathology 11, 583-616, (2016).

Human Engineered Heart Tissue: Analysis of Contractile Force. Mannhardt, I., Breckwoldt, K., Letuffe-Breniere, D., Schaaf, S., Schulz, H., Neuber, C., Benzin, A., Werner, T., Eder, A., Schulze, T., Klampe, B., Christ, T., Hirt, M. N., Hubner, N., Moretti, A., Eschenhagen, T. & Hansen, A. Stem Cell Reports, (2016).

Expiration-Triggered Sinus Arrhythmia Predicts Outcome in Survivors of Acute Myocardial Infarction. Sinnecker, D., Dommasch, M., Steger, A., Berkefeld, A., Hoppmann, P., Muller, A., Gebhardt, J., Barthel, P., Hnatkova, K., Huster, K. M., Laugwitz, K. L., Malik, M. & Schmidt, G. Journal of the American College of Cardiology 67, 2213-2220, (2016).

Targeting Vascular (Endothelial) Dysfunction. Daiber, A., Steven, S., Weber, A., Shuvaev, V. V., Muzykantov, V. R., Laher, I., Li, H., Lamas, S. & Munzel, T. British journal of pharmacology, (2016).

Aav9-Mediated Gene Transfer of Desmin Ameliorates Cardiomyopathy in Desmin-Deficient Mice. Heckmann, M. B., Bauer, R., Jungmann, A., Winter, L., Rapti, K., Strucksberg, K. H., Clemen, C. S., Li, Z., Schroder, R., Katus, H. A. & Muller, O. J. Gene therapy, (2016).

Troponin I and Cardiovascular Risk Prediction in the General Population: The Biomarcare Consortium. Blankenberg, S., Salomaa, V., Makarova, N., Ojeda, F., Wild, P., Lackner, K. J., Jorgensen, T., Thorand, B., Peters, A., Nauck, M., Petersmann, A., Vartiainen, E., Veronesi, G., Brambilla, P., Costanzo, S., Iacoviello, L., Linden, G., Yarnell, J., Patterson, C. C., Everett, B. M. et al. European heart journal, (2016).

Cha2ds2-Vasc Score and Blood Biomarkers to Identify Patients with Atrial High-Rate Episodes and Paroxysmal Atrial Fibrillation. Wakula, P., Neumann, B., Kienemund, J., Thon-Gutschi, E., Stojakovic, T., Manninger, M., Scherr, D., Scharnagl, H., Kapl, M., Pieske, B. & Heinzel, F. R. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).

Marathon Performance but Not Bmi Affects Post-Marathon Pro-Inflammatory and Cartilage Biomarkers. Mundermann, A., Geurts, J., Hugle, T., Nickel, T., Schmidt-Trucksass, A., Halle, M. & Hanssen, H. Journal of sports sciences, 1-8, (2016).

The Soluble Epoxide Hydrolase Determines Cholesterol Homeostasis by Regulating Ampk and Srebp Activity. Mangels, N., Awwad, K., Wettenmann, A., Dos Santos, L. R., Fromel, T. & Fleming, I. Prostaglandins & other lipid mediators, (2016).

Communication through Gap Junctions in the Endothelium. Schmidt, K., Windler, R. & de Wit, C. Advances in Pharmacology, (2016).

Sex-Based Differences in Outcomes with Bivalirudin or Unfractionated Heparin for Transcatheter Aortic Valve Replacement: Results from the Bravo 3 Randomized Trial. Asgar, A., Chandrasekhar, J., Mikhail, G., Webb, J., Lefevre, T., Tamburino, C., Hildick-Smith, D., Hambrecht, R., Van Belle, E., Widder, J., Dumonteil, N., Hink, U., Jeger, R., Linke, A., Dellargyris, E., Gao, P., Mehran, R., Hengstenberg, C., Anthopoulos, P., Dangas, G. et al. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, (2016).

Right Ventricular Long Axis Strain—Validation of a Novel Parameter in Non-Ischemic Dilated Cardiomyopathy Using Standard Cardiac Magnetic Resonance Imaging. Arenja, N., Riffel, J. H., Djiokou, C. N., Andre, F., Fritz, T., Halder, M., Thomas, Z., Kristen, A. V., Korosoglou, G., Katus, H. A. & Buss, S. J. European Journal of Radiology, (2016).

Troponin I Assay for Identification of a Significant Coronary Stenosis in Patients with Suspected Acute Myocardial Infarction and Wide Qrs Complex. von Jeinsen, B., Tzikas, S., Pioro, G., Palapies, L., Zeller, T., Bickel, C., Lackner, K. J., Baldus, S., Blankenberg, S., Muenzel, T., Zeiher, A. M. & Keller, T. PloS one 11, e0154724, (2016).

Serum Microrna-1233 Is a Specific Biomarker for Diagnosing Acute Pulmonary Embolism. Kessler, T., Erdmann, J., Vilne, B., Bruse, P., Kurowski, V., Diemert, P., Schunkert, H. & Sager, H. B. Journal of translational medicine 14, 120, (2016).

Inhibition of Chymotryptic-Like Standard Proteasome Activity Exacerbates Doxorubicin-Induced Cytotoxicity in Primary Cardiomyocytes. Spur, E. M., Althof, N., Respondek, D., Klingel, K., Heuser, A., Overkleeft, H. S. & Voigt, A. Toxicology, (2016).

The Impact of Genome-Wide Association Studies on the Pathophysiology and Therapy of Cardiovascular Disease. Kessler, T., Vilne, B. & Schunkert, H. EMBO Molecular Medicine, (2016).

Essential Role for Premature Senescence of Myofibroblasts in Myocardial Fibrosis. Meyer, K., Hodwin, B., Ramanujam, D., Engelhardt, S. & Sarikas, A. Journal of the American College of Cardiology 67, 2018-2028, (2016).

Microrna Regulation of Macrophages in Human Pathologies. Wei, Y. & Schober, A. Cellular and molecular life sciences : CMLS, (2016).

Novel Pathomechanisms of Cardiomyocyte Dysfunction in a Model of Heart Failure with Preserved Ejection Fraction. Primessnig, U., Schonleitner, P., Holl, A., Pfeiffer, S., Bracic, T., Rau, T., Kapl, M., Stojakovic, T., Glasnov, T., Leineweber, K., Wakula, P., Antoons, G., Pieske, B. & Heinzel, F. R. European journal of heart failure, (2016).

Homoarginine Predicts Mortality in Treatment-Naive Patients with Pulmonary Arterial Hypertension. Atzler, D., Cracowski, J.-L., Cordts, K., Boger, R. H., Humbert, M. & Schwedhelm, E. International journal of cardiology 217, 12-15, (2016).

Coding and Non-Coding Variants in the Shox2 Gene in Patients with Early-Onset Atrial Fibrillation. Hoffmann, S., Clauss, S., Berger, I. M., Weiss, B., Montalbano, A., Roth, R., Bucher, M., Klier, I., Wakili, R., Seitz, H., Schulze-Bahr, E., Katus, H. A., Flachsbart, F., Nebel, A., Guenther, S. P., Bagaev, E., Rottbauer, W., Kaab, S., Just, S. & Rappold, G. A. Basic research in cardiology 111, 36, (2016).

Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists Cause Differential Cardiac Gene Expression in Pressure Overload-Induced Cardiac Hypertrophy. Grune, J., Benz, V., Brix, S., Salatzki, J., Blumrich, A., Hoft, B., Klopfleisch, R., Foryst-Ludwig, A., Kolkhof, P. & Kintscher, U. Journal of cardiovascular pharmacology 67, 402-411, (2016).


Circulating Irisin Concentrations Are Associated with a Favourable Lipid Profile in the General Population. Oelmann, S., Nauck, M., Volzke, H., Bahls, M. & Friedrich, N. PloS one 11, e0154319, (2016).

The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine. Mason, F. E. & Sossalla, S. Journal of cardiovascular pharmacology and therapeutics, (2016).

Pafah1b1 and the Lncrna Nonhsat073641 Maintain an Angiogenic Phenotype in Human Endothelial Cells. Josipovic, I., Fork, C., Preussner, J., Prior, K. K., Iloska, D., Vasconez, A. E., Labocha, S., Angioni, C., Thomas, D., Ferreiros, N., Looso, M., Pullamsetti, S. S., Geisslinger, G., Steinhilber, D., Brandes, R. P. & Leisegang, M. S. Acta physiologica, (2016).

Myoscape Controls Cardiac Calcium Cycling and Contractility Via Regulation of L-Type Calcium Channel Surface Expression. Eden, M., Meder, B., Volkers, M., Poomvanicha, M., Domes, K., Branchereau, M., Marck, P., Will, R., Bernt, A., Rangrez, A., Busch, M., German Mouse Clinic, C., Hrabe de Angelis, M., Heymes, C., Rottbauer, W., Most, P., Hofmann, F. & Frey, N. Nature communications 7, 11317, (2016).

Long-Term Clinical Impact of Polymer-Free Sirolimus-Eluting Stents in Unselected Patients. Sinha, N., Rai, H., Cassese, S., Kumar, S., Kapoor, A. & Kastrati, A. Coronary artery disease, (2016).

A Biobank for Long-Term and Sustainable Research in the Field of Congenital Heart Disease in Germany. Pickardt, T., Niggemeyer, E., Bauer, U. M., Abdul-Khaliq, H. & Competence Network for Congenital Heart Defects, I. Genomics, proteomics & bioinformatics, (2016).

Profiling and Validation of the Circular Rna Repertoire in Adult Murine Hearts. Jakobi, T., Czaja-Hasse, L. F., Reinhardt, R. & Dieterich, C. Genomics, proteomics & bioinformatics, (2016).

Right Ventricular Thrombus Formation in a Patient with Arrhythmogenic Right Ventricular Dysplasia Following Radiofrequency Ablation. Kemmer, S., Lesevic, H., Reents, T., Schunkert, H. & Burgdorf, C. Clinical Case Reports, (2016).

Mismatch between Cardiac Perfusion, Sympathetic Innervation, and Left Ventricular Electroanatomical Map in a Patient with Recurrent Ventricular Tachycardia. Jungen, C., von Gogh, G., Schmitt, C., Kuklik, P., Hoffmann, B., Nakajima, K., Willems, S., Mester, J. & Meyer, C. The American journal of case reports 17, 280-282, (2016).

Comparison of the Effects of a Truncating and a Missense Mybpc3 Mutation on Contractile Parameters of Engineered Heart Tissue. Wijnker, P. J., Friedrich, F. W., Dutsch, A., Reischmann, S., Eder, A., Vollert-Mannhardt, I., Mearini, G., Eschenhagen, T., van der Velden, J. & Carrier, L. Journal of molecular and cellular cardiology, (2016).

Prediction of Appropriate Shocks Using 24-Hour Holter Variables and T-Wave Alternans Following First Implantable Cardioverter-Defibrillator Implantation in Patients with Ischemic or Non-Ischemic Cardiomyopathy Seegers, J., Bergau, L., Exposito, P. M., Bauer, A., Fischer, T., Luthje, L., Hasenfuss, G., Friede, T. & Zabel, M. Am J Cardiol, (2016).

Regulation of Beta-Cell Function and Mass by the Dual Leucine Zipper Kinase. Oetjen, E. Archiv der Pharmazie, (2016).

Antiphospholipid Antibodies in a Large Population-Based Cohort: Genome-Wide Associations and Effects on Monocyte Gene Expression. Muller-Calleja, N., Rossmann, H., Muller, C., Wild, P., Blankenberg, S., Pfeiffer, N., Binder, H., Beutel, M. E., Manukyan, D., Zeller, T. & Lackner, K. J. Thrombosis and haemostasis 116, (2016).

Aav9-Mediated Gene Transfer of Desmin Ameliorates Cardiomyopathy in Desmin-Deficient Mice. Heckmann, M. B., Bauer, R., Jungmann, A., Winter, L., Rapti, K., Strucksberg, K. H., Clemen, C. S., Li, Z., Schroder, R., Katus, H. A. & Muller, O. J. Gene therapy, (2016).

Akap18:Pka-Riialpha Structure Reveals Crucial Anchor Points for Recognition of Regulatory Subunits of Pka. Gotz, F., Roske, Y., Schulz, M. S., Autenrieth, K., Bertinetti, D., Faelber, K., Zuhlke, K., Kreuchwig, A., Kennedy, E., Krause, G., Daumke, O., Herberg, F. W., Heinemann, U. & Klussmann, E. The Biochemical journal, (2016).

Impaired Endothelial Shear Stress Induces Podosome Assembly Via Vegf up-Regulation. Fey, T., Schubert, M., Schneider, H., Fein, E., Kleinert, E., Pohl, U. & Dendorfer, A. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2016).

Induced Pluripotent Stem Cells in Regenerative Medicine. Pane, L. S., My, I. & Moretti, A. Regenerative Medicine - from Protocol to Patient (Book), 51-75, (2016).

Amp-Activated Protein Kinase Alpha1-Sensitive Activation of Ap-1 in Cardiomyocytes. Voelkl, J., Alesutan, I., Primessnig, U., Feger, M., Mia, S., Jungmann, A., Castor, T., Viereck, R., Stockigt, F., Borst, O., Gawaz, M., Schrickel, J. W., Metzler, B., Katus, H. A., Muller, O. J., Pieske, B., Heinzel, F. R. & Lang, F. Journal of molecular and cellular cardiology, (2016).

Challenges to the Translation of Basic Science Findings to Atrial Fibrillation Therapies. Heijman, J. & Dobrev, D. Future cardiology, (2016).

Catheter Ablation of Atrial Fibrillation in Patients with Concomitant Sinus Bradycardia-Insights from the German Ablation Registry. Zylla, M. M., Brachmann, J., Lewalter, T., Hoffmann, E., Kuck, K. H., Andresen, D., Willems, S., Hochadel, M., Senges, J., Katus, H. A. & Thomas, D. Journal of electrocardiology 49, 117-123, (2016).

Cross-Linking Gpvi-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation. Jamasbi, J., Megens, R. T. A., Bianchini, M., Uhland, K., Munch, G., Ungerer, M., Sherman, S., Faussner, A., Brandl, R., John, C., Buchner, J., Weber, C., Lorenz, R., Elia, N. & Siess, W. JACC: Basic to Translational Science 1, 131-142, (2016).

Angiographic and Clinical Outcomes of Patients Treated with Everolimus-Eluting Bioresorbable Stents in Routine Clinical Practice: Results of the Isar-Absorb Registry. Hoppmann, P., Kufner, S., Cassese, S., Wiebe, J., Schneider, S., Pinieck, S., Scheler, L., Bernlochner, I., Joner, M., Schunkert, H., Laugwitz, K. L., Kastrati, A. & Byrne, R. A. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 87, 822-829, (2016).

Cathelicidin Regulates Myeloid Cell Accumulation in Adipose Tissue and Promotes Insulin Resistance During Obesity. Braster, Q., Silvestre-Roig, C., Hartwig, H., Kusters, P., Aarts, S., den Toom, M., Gallo, R. L., Weber, C., Lutgens, E. & Soehnlein, O. Thrombosis and haemostasis 115, (2016).

Comprehensive Cardiac Magnetic Resonance Imaging in Patients with Suspected Myocarditis: The Myoracer-Trial. Lurz, P., Luecke, C., Eitel, I., Fohrenbach, F., Frank, C., Grothoff, M., de Waha, S., Rommel, K. P., Lurz, J. A., Klingel, K., Kandolf, R., Schuler, G., Thiele, H. & Gutberlet, M. Journal of the American College of Cardiology 67, 1800-1811, (2016).

Human Validation of Genes Associated with a Murine Atherosclerotic Phenotype. Pasterkamp, G., van der Laan, S. W., Haitjema, S., Asl, H. F., Siemelink, M. A., Bezemer, T., van Setten, J., Dichgans, M., Malik, R., Worrall, B. B., Schunkert, H., Samani, N. J., de Kleijn, D. P., Markus, H. S., Hoefer, I. E., Michoel, T., de Jager, S. C., Bjorkegren, J. L., den Ruijter, H. M. & Asselbergs, F. W. Arteriosclerosis, thrombosis, and vascular biology, (2016).

[Cardiovascular Risk of Androgen Deprivation Therapy for Treatment of Hormone-Dependent Prostate Cancer : Differences between Gnrh Antagonists and Gnrh Agonists]. Tschope, C., Kherad, B., Spillmann, F., Schneider, C. A., Pieske, B. & Krackhardt, F. Herz, (2016).

Association of Progression or Regression of Coronary Artery Atherosclerosis with Long-Term Prognosis. Ndrepepa, G., Iijima, R., Kufner, S., Braun, S., Cassese, S., Byrne, R. A., Sorges, J., Schulz-Schupke, S., Hoppmann, P., Fussaro, M., Laugwitz, K. L., Schunkert, H. & Kastrati, A. American heart journal, (2016).

How to Keep on Going: Editorial Comment on the Long-Term Effects of a Randomized Trial Comparing Aerobic Interval Versus Continuous Training in Coronary Artery Disease Patients: One-Year Data from the Saintex-Cad Study. Krankel, N. European journal of preventive cardiology, (2016).

Synchronization of Endothelial Dll4-Notch Dynamics Switch Blood Vessels from Branching to Expansion. Ubezio, B., Blanco, R. A., Geudens, I., Stanchi, F., Mathivet, T., Jones, M. L., Ragab, A., Bentley, K. & Gerhardt, H. eLife 5, (2016).

Differences in the Clinical Profile and Outcomes of Typical and Atypical Takotsubo Syndrome - Data from the International Takotsubo Registry. Ghadri, J. R., Cammann, V. L., Napp, L. C., Jurisic, S., Diekmann, J., Bataiosu, D. R., Seifert, B., Jaguszewski, M., Sarcon, A., Neumann, C. A., Geyer, V., Prasad, A., Bax, J. J., Ruschitzka, F., Luscher, T. F., Templin, C. & Registry, f. t. I. T. I. JAMA Cardiol., (2016).

Calibrating Random Forests for Probability Estimation. Dankowski, T. & Ziegler, A. Statistics in medicine, (2016).

Cachexia and Right Ventricular Dysfunction in Chronic Heart Failure: What Is the Chicken and What the Egg? Bahls, M. & Felix, S. B. European heart journal, (2016).

Hide and Seek: Protein-Coding Sequences inside "Non-Coding" Rnas. Oehler, D. & Haas, J. Genomics, proteomics & bioinformatics, (2016).

Do Little Interactions Get Lost in Dark Random Forests? Wright, M. N., Ziegler, A. & Konig, I. R. BMC bioinformatics 17, 145, (2016).

[Rehabilitation in Heart Failure]. Reibis, R. K., Schlitt, A., Glatz, J., Langheim, E. H., Guha, M., Halle, M., Boscheri, A., Hegeler-Molkewehrum, C. & Voller, H. Die Rehabilitation 55, 115-129, (2016).

[Percutaneous Implantable Transcatheter Pacemaker]. Meyer, C., Jungen, C., Gosau, N., Hoffmann, B., Eickholt, C. & Willems, S. Deutsche medizinische Wochenschrift 141, 574-577, (2016).

Rotigotine's Effect on Plm-Associated Blood Pressure Elevations in Restless Legs Syndrome. Bauer, A., Cassel, W., Benes, H., Kesper, K., Rye, D., Sica, D., Winkelman, J. W., Bauer, L., Grieger, F., Joeres, L., Moran, K., Schollmayer, E., Whitesides, J., Carney, H. C., Walters, A. S., Oertel, W. & Trenkwalder, C. Neurology, (2016).

Low Homoarginine Levels in the Prognosis of Patients with Acute Chest Pain. Atzler, D., Baum, C., Ojeda, F., Keller, T., Cordts, K., Schnabel, R. B., Choe, C. U., Lackner, K. J., Munzel, T., Boger, R. H., Blankenberg, S., Schwedhelm, E. & Zeller, T. Journal of the American Heart Association 5, (2016).

M1 Signature Mediators in Atheroma-Derived Single Cell Secretome of Symptomatic Plaques. Insight ... Inflammatory Pathways Activated within Instable Plaques Which Promote a Pro-Inflammatory M1 Macrophage Polarisation. Steffens, S. Thrombosis and haemostasis 115, (2016).

Scanning and Resetting the Phase of a Spinned Spiral Wave Using Periodic Far Field Pulses. Shajahan, T. K., Berg, S., Luther, S., Krinski, V. & Bittihn, P. New J. Phys. 18, (2016).

Risk Factors for Heart Failure Are Associated with Alterations of the Lv End-Diastolic Pressure-Volume Relationship in Non-Heart Failure Individuals: Data from a Large-Scale, Population-Based CohortSchwarzl, M., Ojeda, F., Zeller, T., Seiffert, M., Becher, P. M., Munzel, T., Wild, P. S., Blettner, M., Lackner, K. J., Pfeiffer, N., Beutel, M. E., Blankenberg, S. & Westermann, D. European heart journal, (2016).

Atrial Fibrillation in Women: Epidemiology, Pathophysiology, Presentation, and Prognosis. Ko, D., Rahman, F., Schnabel, R. B., Yin, X., Benjamin, E. J. & Christophersen, I. E. Nature reviews. Cardiology, (2016).

Circulating Exosomal Micrornas Predict Functional Recovery after Mitraclip Repair of Severe Mitral Regurgitation. Kasner, M., Gast, M., Galuszka, O., Stroux, A., Rutschow, S., Wang, X., Dohmen, P., Skurk, C., Landmesser, U., Poller, W. & Gross, M. International journal of cardiology, (2016).

Dyrk1a Regulates the Cardiomyocyte Cell Cycle Via D-Cyclin Dependent Rb/E2f-SignalingHille, S., Dierck, F., Kuhl, C., Sosna, J., Adam-Klages, S., Adam, D., Lullmann-Rauch, R., Frey, N. & Kuhn, C. Cardiovascular research, (2016).

Dual Leucine Zipper Kinase (Map3k12) Modulators: A Patent Review (2010-2015). Oetjen, E. & Lemcke, T. Expert opinion on therapeutic patents, (2016).

The Combined Effects of Ranolazine and Dronedarone on Human Atrial and Ventricular ElectrophysiologyHartmann, N., Mason, F. E., Braun, I., Pabel, S., Voigt, N., Schotola, H., Fischer, T. H., Dobrev, D., Danner, B. C., Renner, A., Gummert, J., Belardinelli, L., Frey, N., Maier, L. S., Hasenfuss, G. & Sossalla, S. JMCC, (2016).

Association of Type D Personality with Cognitive Functioning in Individuals with and without Cardiovascular Disease — the Gutenberg Health Study. Unterrainer, J., Michal, M., Rahm, B., Hadzibegovic, J., Wild, P. S., Schulz, A., Munzel, T., Blettner, M., Lackner, K., Pfeiffer, N., Blankenberg, S., Denollet, J. & Beutel, M. E. International journal of cardiology 214, 256-261, (2016).

Aortic Annulus to Left Coronary Distance as a Predictor for Persistent Left Bundle Branch Block after Tavi. Hein-Rothweiler, R., Jochheim, D., Rizas, K., Egger, A., Theiss, H., Bauer, A., Massberg, S. & Mehilli, J. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, (2016).

Cardiovascular Magnetic Resonance Myocardial Feature Tracking: Concepts and Clinical Applications. Schuster, A., Hor, K. N., Kowallick, J. T., Beerbaum, P. & Kutty, S. Circulation. Cardiovascular imaging 9, (2016).

Evaluation of C-Terminal Agrin Fragment as a Marker of Muscle Wasting in Patients after Acute Stroke During Early RehabilitationScherbakov, N., Knops, M., Ebner, N., Valentova, M., Sandek, A., Grittner, U., Dahinden, P., Hettwer, S., Schefold, J. C., von Haehling, S., Anker, S. D., Joebges, M. & Doehner, W. Journal of cachexia, sarcopenia and muscle 7, 60-67, (2016).

Searching for a Relevant Definition of Sarcopenia: Results from the Cross-Sectional Epidos StudyScherbakov, N. & Doehner, W. Journal of cachexia, sarcopenia and muscle 7, 100-101, (2016).

Prospective Evaluation of 18f-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional OutcomeRischpler, C., Dirschinger, R. J., Nekolla, S. G., Kossmann, H., Nicolosi, S., Hanus, F., van Marwick, S., Kunze, K. P., Meinicke, A., Gotze, K., Kastrati, A., Langwieser, N., Ibrahim, T., Nahrendorf, M., Schwaiger, M. & Laugwitz, K. L. Circulation. Cardiovascular imaging 9, e004316, (2016).

Cardiovascular Magnetic Resonance in Diabetic Patients: The Method of Choice? Nagel, E. Circulation. Cardiovascular imaging 9, e004699, (2016).

Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia. Khera, A. V., Won, H. H., Peloso, G. M., Lawson, K. S., Bartz, T. M., Deng, X., van Leeuwen, E. M., Natarajan, P., Emdin, C. A., Bick, A. G., Morrison, A. C., Brody, J. A., Gupta, N., Nomura, A., Kessler, T., Duga, S., Bis, J. C., van Duijn, C. M., Cupples, L. A., Psaty, B. et al. Journal of the American College of Cardiology, (2016).

Vagus Nerve Stimulation for the Treatment of Heart Failure: The Inovate-Hf Trial. Gold, M. R., Van Veldhuisen, D. J., Hauptman, P. J., Borggrefe, M., Kubo, S. H., Lieberman, R. A., Milasinovic, G., Berman, B. J., Djordjevic, S., Neelagaru, S., Schwartz, P. J., Starling, R. C. & Mann, D. L. Journal of the American College of Cardiology, (2016).

High on-Treatment Platelet Reactivity and Outcomes after Percutaneous Endovascular Procedures in Patients with Peripheral Artery DiseaseBernlochner, I., Jaitner, J., Fries, V., Dommasch, M., Mayer, K., Ott, I., Langwieser, N., Fusaro, M., Laugwitz, K. L., Kastrati, A. & Ibrahim, T. VASA. Zeitschrift fur Gefasskrankheiten 45, 155-161, (2016).

Coding Variation in Angptl4, Lpl, and Svep1 and the Risk of Coronary Disease. Myocardial Infarction, G. & Investigators, C. A. E. C. The New England journal of medicine 374, 1134-1144, (2016).


Distribution of Antiphospholipid Antibodies in a Large Population-Based German Cohort. Manukyan, D., Rossmann, H., Schulz, A., Zeller, T., Pfeiffer, N., Binder, H., Munzel, T., Beutel, M. E., Muller-Calleja, N., Wild, P. S. & Lackner, K. J. Clinical chemistry and laboratory medicine, (2016).

Defects in Trpm7 Channel Function Deregulate Thrombopoiesis through Altered Cellular Mg(2+) Homeostasis and Cytoskeletal Architecture. Stritt, S., Nurden, P., Favier, R., Favier, M., Ferioli, S., Gotru, S. K., van Eeuwijk, J. M., Schulze, H., Nurden, A. T., Lambert, M. P., Turro, E., Burger-Stritt, S., Matsushita, M., Mittermeier, L., Ballerini, P., Zierler, S., Laffan, M. A., Chubanov, V., Gudermann, T., Nieswandt, B. et al. Nature communications 7, 11097, (2016).

Ccr5+T-Bet+Foxp3+ Effector Cd4 T Cells Drive Atherosclerosis. Li, J., McArdle, S., Gholami, A., Kimura, T., Wolf, D., Gerhardt, T., Miller, J., Weber, C. & Ley, K. Circulation research, (2016).

Pulmonary Targeting of Adeno-Associated Viral Vectors by Next-Generation Sequencing-Guided Screening of Random Capsid Displayed Peptide Libraries. Korbelin, J., Sieber, T., Michelfelder, S., Lunding, L., Spies, E., Hunger, A., Alawi, M., Rapti, K., Indenbirken, D., Muller, O. J., Pasqualini, R., Arap, W., Kleinschmidt, J. A. & Trepel, M. Molecular therapy : the journal of the American Society of Gene Therapy, (2016).

Hypoxia-Induced Endothelial-Mesenchymal Transition Is Associated with Rasal1 Promoter Hypermethylation in Human Coronary Endothelial CellsXu, X., Tan, X., Hulshoff, M. S., Wilhelmi, T., Zeisberg, M. & Zeisberg, E. M. FEBS Letters, (2016).

Statins and Risk of Poststroke Hemorrhagic Complications. Scheitz, J. F., MacIsaac, R. L., Abdul-Rahim, A. H., Siegerink, B., Bath, P. M., Endres, M., Lees, K. R., Nolte, C. H. & collaboration, V. Neurology, (2016).

Atrial-Selective Potassium Channel Blockers Voigt, N. & Dobrev, D. Cardiac Electrophysiology Clinics, (2016).

Mir-223-Igf-Ir Signaling in Hypoxia- and Load-Induced Right Ventricular Failure: A Novel Therapeutic Approach. Shi, L., Kojonazarov, B., Elgheznawy, A., Popp, R., Dahal, B. K., Bohm, M., Pullamsetti, S. S., Ghofrani, H. A., Godecke, A., Jungmann, A., Katus, H. A., Muller, O. J., Schermuly, R. T., Fisslthaler, B., Seeger, W. & Fleming, I. Cardiovascular research, (2016).

Essential Light Chain S195 Phosphorylation Is Required for Cardiac Adaptation under Physical Stress. Scheid, L. M., Mosqueira, M., Hein, S., Kossack, M., Juergensen, L., Mueller, M., Meder, B., Fink, R. H., Katus, H. A. & Hassel, D. Cardiovascular research, (2016).

The Endoplasmic Reticulum Chaperone Calnexin Is a Nadph Oxidase Nox4 Interacting ProteinPrior, K. K., Wittig, I., Leisegang, M. S., Groenendyk, J., Weissmann, N., Michalak, M., Jansen-Durr, P., Shah, A. M. & Brandes, R. P. The Journal of biological chemistry 291, 7045-7059, (2016).

Serum Matrix Metalloproteinases as Quantitative Biomarkers for Myocardial Fibrosis and Sudden Cardiac Death Risk Stratification in Patients with Hypertrophic Cardiomyopathy. Munch, J., Avanesov, M., Bannas, P., Saring, D., Kramer, E., Mearini, G., Carrier, L., Suling, A., Lund, G. & Patten, M. Journal of cardiac failure, (2016).

Common and Rare Genetic Variation in Ccr2, Ccr5, or Cx3cr1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits. Golbus, J. R., Stitziel, N. O., Zhao, W., Xue, C., Farrall, M., McPherson, R., Erdmann, J., Deloukas, P., Watkins, H., Schunkert, H., Samani, N. J., Saleheen, D., Kathiresan, S. & Reilly, M. P. Circulation. Cardiovascular genetics, (2016).

Genome-Wide Study for Circulating Metabolites Identifies 62 Loci and Reveals Novel Systemic Effects of Lpa. Kettunen, J., Demirkan, A., Wurtz, P., Draisma, H. H., Haller, T., Rawal, R., Vaarhorst, A., Kangas, A. J., Lyytikainen, L. P., Pirinen, M., Pool, R., Sarin, A. P., Soininen, P., Tukiainen, T., Wang, Q., Tiainen, M., Tynkkynen, T., Amin, N., Zeller, T., Beekman, M. et al. Nature communications 7, 11122, (2016).

Immunochip Analysis Identifies Association of the Rad50/Il13 Region with Human Longevity. Flachsbart, F., Ellinghaus, D., Gentschew, L., Heinsen, F. A., Caliebe, A., Christiansen, L., Nygaard, M., Christensen, K., Blanche, H., Deleuze, J. F., Derbois, C., Galan, P., Buning, C., Brand, S., Peters, A., Strauch, K., Muller-Nurasyid, M., Hoffmann, P., Nothen, M. M., Lieb, W. et al. Aging cell, (2016).

Effects of Renal Denervation on Renal Artery Function in Humans: Preliminary Study. Doltra, A., Hartmann, A., Stawowy, P., Goubergrits, L., Kuehne, T., Wellnhofer, E., Gebker, R., Schneeweis, C., Schnackenburg, B., Esler, M., Fleck, E. & Kelle, S. PloS one 11, e0150662, (2016).

Durability of Bioprostheses for the Tricuspid Valve in Patients with Congenital Heart Disease. Burri, M., Vogt, M. O., Horer, J., Cleuziou, J., Kasnar-Samprec, J., Kuhn, A., Lange, R. & Schreiber, C. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, (2016).

Impact of Common Β1-Adrenergic Receptor Polymorphisms on the Interaction with Agonistic Autoantibodies in Dilated Cardiomyopathy. Bornholz, B., Hanzen, B., Reinke, Y., Felix, S. B. & Boege, F. International journal of cardiology 214, (2016).

Epidemiologic Research Topics in Germany: A Keyword Network Analysis of 2014 Dgepi Conference Presentations. Peter, R. S., Brehme, T., Volzke, H., Muche, R., Rothenbacher, D. & Buchele, G. European journal of epidemiology, (2016).

Randomized Trial of Polymer-Free Sirolimus- and Probucol-Eluting Stents Versus Durable Polymer Zotarolimus-Eluting Stents: Five-Year Results of the Isar-Test 5 TrialKufner, S., Sorges, J., Mehilli, J., Cassese, S., Repp, J., Wiebe, J., Lohaus, R., Lahmann, A., Rheude, T., Ibrahim, T., Massberg, S., Laugwitz, K. L., Kastrati, A., Byrne, R. A. & Investigators, I.-T. JACC. Cardiovascular interventions, (2016).

Asymmetric Dimethylarginine, Related Arginine Derivatives and Incident Atrial Fibrillation. Schnabel, R. B., Maas, R., Wang, N., Yin, X., Larson, M. G., Levy, D., Ellinor, P. T., Lubitz, S. A., McManus, D., Magnani, J. W., Atzler, D., Böger, R. H., Schwedhelm, E., Ramachandran, V. S. & Benjamin, E. J. American heart journal, (2016).

Association of Plasma Abeta40 Peptides, but Not Abeta42, with Coronary Artery Disease and Diabetes Mellitus. Roeben, B., Maetzler, W., Vanmechelen, E., Schulte, C., Heinzel, S., Stellos, K., Godau, J., Huber, H., Brockmann, K., Wurster, I., Gaenslen, A., Gruner, E., Niebler, R., Eschweiler, G. W., Berg, D. & team, T. s. Journal of Alzheimer's disease : JAD, (2016).

Response to Letter Regarding Article, "Upregulation of K2p3.1 K+ Current Causes Action Potential Shortening in Patients with Chronic Atrial Fibrillation". Schmidt, C., Wiedmann, F., Voigt, N., Zhou, X. B., Heijman, J., Lang, S., Albert, V., Kallenberger, S., Ruhparwar, A., Szabo, G., Kallenbach, K., Karck, M., Borggrefe, M., Biliczki, P., Ehrlich, J. R., Baczko, I., Lugenbiel, P., Schweizer, P. A., Donner, B. C., Katus, H. A. et al. Circulation 133, e440-441, (2016).

High Levels of Thyroid-Stimulating Hormone Are Associated with Aortic Wall Thickness in the General PopulationIttermann, T., Lorbeer, R., Dorr, M., Schneider, T., Quadrat, A., Hesselbarth, L., Wenzel, M., Lehmphul, I., Kohrle, J., Mensel, B. & Volzke, H. European radiology, (2016).

Association of Smoking with Myocardial Injury and Clinical Outcome in Patients Undergoing Mechanical Reperfusion for St-Elevation Myocardial Infarction. Reinstadler, S. J., Eitel, C., Fuernau, G., de Waha, S., Desch, S., Mende, M., Metzler, B., Schuler, G., Thiele, H. & Eitel, I. European heart journal cardiovascular Imaging, (2016).

Epigenetic Regulation of Diacylglycerol Kinase Alpha Promotes Radiation-Induced Fibrosis. Weigel, C., Veldwijk, M. R., Oakes, C. C., Seibold, P., Slynko, A., Liesenfeld, D. B., Rabionet, M., Hanke, S. A., Wenz, F., Sperk, E., Benner, A., Rosli, C., Sandhoff, R., Assenov, Y., Plass, C., Herskind, C., Chang-Claude, J., Schmezer, P. & Popanda, O. Nature communications 7, 10893, (2016).

Estimating Absolute-Phase Maps Using Espirit and Virtual Conjugate Coils. Uecker, M. & Lustig, M. Magnetic resonance in medicine, (2016).

Optogenetic Light Crafting Tools for the Control of Cardiac ArrhythmiasRichter, C., Christoph, J., Lehnart, S. E. & Luther, S. Methods in molecular biology 1408, 293-302, (2016).

The Factor in Edhf: Cytochrome P450 Derived Lipid Mediators and Vascular Signaling. Fleming, I. Vascular pharmacology, (2016).

Relaxin Treatment in an Ang-Ii-Based Transgenic Preeclamptic-Rat Model. Haase, N., Golic, M., Herse, F., Rugor, J., Linz, D., Solano, M. E., Muller, D. N. & Dechend, R. PloS one 11, e0150743, (2016).

Model-Based Reconstruction for Real-Time Phase-Contrast Flow Mri: Improved Spatiotemporal Accuracy. Tan, Z., Roeloffs, V., Voit, D., Joseph, A. A., Untenberger, M., Merboldt, K. D. & Frahm, J. Magnetic resonance in medicine, (2016).

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The Charge Consortium. Dehghan, A., Bis, J. C., White, C. C., Smith, A. V., Morrison, A. C., Cupples, L. A., Trompet, S., Chasman, D. I., Lumley, T., Volker, U., Buckley, B. M., Ding, J., Jensen, M. K., Folsom, A. R., Kritchevsky, S. B., Girman, C. J., Ford, I., Dorr, M., Salomaa, V., Uitterlinden, A. G. et al. PloS one 11, e0144997, (2016).

Gut Microbiota Impact on Stroke Outcome: Fad or Fact? Winek, K., Meisel, A. & Dirnagl, U. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (2016).

Impact of the Bioresorbable Vascular Scaffold Surface Area on on-Treatment Platelet ReactivityGross, L., Sibbing, D., Eickhoff, M., Baquet, M., Orban, M., Krieg, A., Grujic, K., Theiss, H. D., Brunner, S., Teupser, D., Holdt, L., Massberg, S. & Mehilli, J. Platelets, 1-6, (2016).

Happy Heart Syndrome: Role of Positive Emotional Stress in Takotsubo Syndrome. Ghadri, J. R., Sarcon, A., Diekmann, J., Bataiosu, D. R., Cammann, V. L., Jurisic, S., Napp, L. C., Jaguszewski, M., Scherff, F., Brugger, P., Jancke, L., Seifert, B., Bax, J. J., Ruschitzka, F., Luscher, T. F., Templin, C. & Inter, T. A. K. C.-i. European heart journal, (2016).

Plasma Microrna-21 for the Early Prediction of Acute Kidney Injury in Patients Undergoing Major Cardiac Surgery. Gaede, L., Liebetrau, C., Blumenstein, J., Troidl, C., Dorr, O., Kim, W. K., Gottfried, K., Voss, S., Berkowitsch, A., Walther, T., Nef, H., Hamm, C. W. & Mollmann, H. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2016).

Cyp2c19 in Acs Patients: Could Genotyping Have a Role in Medically Managed Patients or Beyond? Sibbing, D., Gross, L. & Massberg, S. Journal of the American College of Cardiology 67, 948-950, (2016).

Cardiomyocyte-Specific Overexpression of Oestrogen Receptor Beta Improves Survival and Cardiac Function after Myocardial Infarction in Female and Male Mice. Schuster, I., Mahmoodzadeh, S., Dworatzek, E., Jaisser, F., Messaoudi, S., Morano, I. & Regitz-Zagrosek, V. Clinical science 130, 365-376, (2016).

Bioresorbable Coronary Scaffold Thrombosis: Multicenter Comprehensive Analysis of Clinical Presentation, Mechanisms, and Predictors. Puricel, S., Cuculi, F., Weissner, M., Schmermund, A., Jamshidi, P., Nyffenegger, T., Binder, H., Eggebrecht, H., Munzel, T., Cook, S. & Gori, T. Journal of the American College of Cardiology 67, 921-931, (2016).

Angiopoietin-2-Induced Blood-Brain Barrier Compromise and Increased Stroke Size Are Rescued by Ve-Ptp-Dependent Restoration of Tie2 Signaling. Gurnik, S., Devraj, K., Macas, J., Yamaji, M., Starke, J., Scholz, A., Sommer, K., Di Tacchio, M., Vutukuri, R., Beck, H., Mittelbronn, M., Foerch, C., Pfeilschifter, W., Liebner, S., Peters, K. G., Plate, K. H. & Reiss, Y. Acta neuropathologica, (2016).

Bioresorbable Vascular Scaffold Technology Benefits from Healthy Skepticism. Cassese, S. & Kastrati, A. Journal of the American College of Cardiology 67, 932-935, (2016).

Prognostic Value of Undetectable Hs Troponin T in Suspected Acute Coronary Syndrome. Vafaie, M., Slagman, A., Mockel, M., Hamm, C., Huber, K., Muller, C., Vollert, J. O., Blankenberg, S., Katus, H. A., Liebetrau, C., Giannitsis, E. & Searle, J. The American journal of medicine 129, 274-282 e272, (2016).

Are the Associations of Cardiac Acceleration and Deceleration Capacities with Fine Metal Particulate in Welders Mediated by Inflammation? Umukoro, P. E., Wong, J. Y., Cavallari, J. M., Fang, S. C., Lu, C., Lin, X., Mittleman, M. A., Schmidt, G. & Christiani, D. C. Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 58, 232-237, (2016).

Long-Term Metal Pm2.5 Exposures Decrease Cardiac Acceleration and Deceleration Capacities in Welders. Umukoro, P. E., Fan, T., Zhang, J., Cavallari, J. M., Fang, S. C., Lu, C., Lin, X., Mittleman, M. A., Schmidt, G. & Christiani, D. C. Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 58, 227-231, (2016).

Genome-Wide Association Studies Identify Genetic Loci Associated with Albuminuria in DiabetesTeumer, A., Tin, A., Sorice, R., Gorski, M., Yeo, N. C., Chu, A. Y., Li, M., Li, Y., Mijatovic, V., Ko, Y. A., Taliun, D., Luciani, A., Chen, M. H., Yang, Q., Foster, M. C., Olden, M., Hiraki, L. T., Tayo, B. O., Fuchsberger, C., Dieffenbach, A. K. et al. Diabetes 65, 803-817, (2016).

Combined Positron Emission Tomography and Magnetic Resonance as Translational Tool in Cardiology. Schwaiger, M. Circulation. Cardiovascular imaging 9, e004549, (2016).

Efficacy, High Procedural Safety and Rapid Optimization of Cryoballoon Atrial Fibrillation Ablation in the Hands of a New Operator. Scholz, E., Lungenbiel, P., Schweizer, P. A., Xynogalos, P., Seyler, C., Zietron, E., Becker, R., Katus, H. A. & Thomas, D. JAFIB, (2016).

Recent Developments and Controversies in the Treatment of Resistant HypertensionKuhl, C., Frey, N. & Frank, D. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 124, 178-186, (2016).

Solid Right Ventricular Compression by Intraventricular Septum-Hematoma Induced after Percutaneous Coronary Intervention. El-Battrawy, I., Akin, I., Munz, B., Leistner, D. M., Behnes, M., Henzler, T., Haubenreisser, H., Papavassiliu, T., Borggrefe, M. & Lehmann, R. Case Reports in Cardiology 2016, (2016).

Mr Imaging of Coronary Arteries and Plaques. Dweck, M. R., Puntman, V., Vesey, A. T., Fayad, Z. A. & Nagel, E. JACC. Cardiovascular imaging 9, 306-316, (2016).

Intestinal Congestion and Right Ventricular Dysfunction: A Link with Appetite Loss, Inflammation, and Cachexia in Chronic Heart Failure. Valentova, M., Von Haehling, S., Bauditz, J., Doehner, W., Ebner, N., Bekfani, T., Elsner, S., Sliziuk, V., Scherbakov, N., Murin, J., Anker, S. D. & Sandek, A. European heart journal, (2016).

Mitral Valve Insufficiency. Rudolph, V. & Lutter, G. Aktuel Kardiol 5, 59-62, (2016). 

Blood Flow Drives Lumen Formation by Inverse Membrane Blebbing During Angiogenesis in Vivo. Gebala, V., Collins, R., Geudens, I., Phng, L. K. & Gerhardt, H. Nature cell biology, (2016).

[Exercise Training in the Therapy of Heart Diseases : Current Evidence and Future Options]. Schwarz, S., Boscheri, A., Christle, J., Duvinage, A., Esefeld, K., Fricke, H., Pitsch, N., Pressler, A., Weichenberger, M. & Halle, M. Herz, (2016).

Distribution of Mirna Expression across Human Tissues. Ludwig, N., Leidinger, P., Becker, K., Backes, C., Fehlmann, T., Pallasch, C., Rheinheimer, S., Meder, B., Stahler, C., Meese, E. & Keller, A. Nucleic acids research, (2016).

Computational Detection of Stage-Specific Transcription Factor Clusters During Heart Development. Zeidler, S., Meckbach, C., Tacke, R., Raad, F. S., Roca, A., Uchida, S., Zimmermann, W. H., Wingender, E. & Gultas, M. Front. Genet., (2016).

Transcoronary Gradients of Vascular Mirnas and Coronary Atherosclerotic Plaque Characteristics. Leistner, D. M., Boeckel, J. N., Reis, S. M., Thome, C. E., De Rosa, R., Keller, T., Palapies, L., Fichtlscherer, S., Dimmeler, S. & Zeiher, A. M. European heart journal, (2016).

The Selective Jak1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both with Systemic Administration and Aerosol Inhalation. Deuse, T., Hua, X., Stubbendorff, M., Spin, J. M., Neofytou, E., Taylor, V., Chen, Y., Park, G., Fink, J. B., Renne, T., Kiefmann, M., Kiefmann, R., Reichenspurner, H., Robbins, R. C. & Schrepfer, S. Transplantation, (2016).

Shock Index as a Predictor of Myocardial Damage and Clinical Outcome in St-Elevation Myocardial Infarction. Reinstadler, S. J., Fuernau, G., Eitel, C., de Waha, S., Desch, S., Metzler, B., Schuler, G., Thiele, H. & Eitel, I. Circulation journal : official journal of the Japanese Circulation Society, (2016).

Serum Androgen Concentrations and Subclinical Measures of Cardiovascular Disease in Men and Women. Kische, H., Gross, S., Wallaschofski, H., Volzke, H., Dorr, M., Nauck, M., Felix, S. B. & Haring, R. Atherosclerosis 247, 193-200, (2016).

Right Ventricular Imaging in 25 Seconds: Evaluating the Use of Sparse Sampling Cine with Iterative Reconstruction for Volumetric Analysis of the Right Ventricle. Haubenreisser, H., Henzler, T., Sudarski, S., Zenge, M. O., Schmidt, M., Nadar, M. S., Borggrefe, M., Schoenberg, S. O. & Papavassiliu, T. Investigative radiology, (2016).

Diplopia on Vorapaxar: An Unexpected Side Effect Emerging Only at Second Glance. Gross, L. & Sibbing, D. Thrombosis and haemostasis 115, (2016).

Platelet Function Testing in Patients on Antiplatelet Medications. Gross, L., Aradi, D. & Sibbing, D. Seminars in thrombosis and hemostasis, (2016).

Structure-Based Design of Peptidic Inhibitors of the Interaction between Cc Chemokine Ligand 5 (Ccl5) and Human Neutrophil Peptides 1 (Hnp1). Wichapong, K., Alard, J. E., Ortega-Gomez, A., Weber, C., Hackeng, T. M., Soehnlein, O. & Nicolaes, G. A. Journal of medicinal chemistry, (2016).

Cardiogenic Shock: How Long Does the Storm Last? Kastrati, A., Colleran, R. & Ndrepepa, G. Journal of the American College of Cardiology 67, 748-750, (2016).

Association of Increased Cd8 and Persisting Crp Levels with Restenosis in Hiv Patients after Coronary Stenting: The Isar Hiv Study. Schneider, S., Spinner, C. D., Cassese, S., Promny, D., Hapfelmeier, A., Byrne, R. A., Baumann, M., Jager, H., Steinlechner, E., Laugwitz, K. L. & Kastrati, A. Aids, (2016).

The Brain Renin-Angiotensin System Plays a Crucial Role in Regulating Body Weight in Diet-Induced Rat Obesity. Winkler, M., Schuchard, J., Stolting, I., Vogt, F. M., Barkhausen, J., Thorns, C., Bader, M. & Raasch, W. British journal of pharmacology, (2016).

Long Noncoding Rna Chast Promotes Cardiac Remodeling. Viereck, J., Kumarswamy, R., Foinquinos, A., Xiao, K., Avramopoulos, P., Kunz, M., Dittrich, M., Maetzig, T., Zimmer, K., Remke, J., Just, A., Fendrich, J., Scherf, K., Bolesani, E., Schambach, A., Weidemann, F., Zweigerdt, R., de Windt, L. J., Engelhardt, S., Dandekar, T. et al. Science translational medicine 8, 326ra322, (2016).

Comparison of Characteristics of Patients ≤ 45 Years Versus >45 Years with St-Elevation Myocardial Infarction (from the Aida Stemi Cmr Substudy). Reinstadler, S. J., Eitel, C., Thieme, M., Metzler, B., Poess, J., Desch, S., Thiele, H. & Eitel, I. Am J Cardiol, (2016).

Impact of Pcsk9 Inhibition on Coronary Atheroma Progression: Rationale and Design of Glagov (Global Assessment of Plaque Regression with a Pcsk9 Antibody as Measured by Intravascular Ultrasound). Puri, R., Nissen, S. E., Somaratne, R., Cho, L., Kastelein, J. J. P., Ballantyne, C. M., Koenig, W., Anderson, T. J., Yang, J., Kassahun, H., Wasserman, S. H., Scott, R., Borgman, M. & Nicholls, S. J. American heart journal 10.1016/j.ahj.2016.01.019, (2016).

Relation of Gamma-Glutamyl Transferase to Cardiovascular Events in Patients with Acute Coronary Syndromes. Ndrepepa, G., Braun, S., Cassese, S., Fusaro, M., Laugwitz, K. L., Schunkert, H. & Kastrati, A. Am J Cardiol, (2016).

Combined Implantation of Dual-Chamber Icd and Optimizer through a Persistent Left Superior Vena Cava. Fastenrath, F., Roger, S., Akin, I., Borggrefe, M. & Kuschyk, J. Anatolian journal of cardiology 16, 138-140, (2016).

Deep Characterization of Blood Cell Mirnomes by Ngs. Schwarz, E. C., Backes, C., Knorck, A., Ludwig, N., Leidinger, P., Hoxha, C., Schwar, G., Grossmann, T., Muller, S. C., Hart, M., Haas, J., Galata, V., Muller, I., Fehlmann, T., Eichler, H., Franke, A., Meder, B., Meese, E., Hoth, M. & Keller, A. Cellular and molecular life sciences : CMLS, (2016).

Differential Regulation of Aldose Reductase Expression During Macrophage Polarization Depends on Hyperglycemia. Erbel, C., Rupp, G., Domschke, G., Linden, F., Akhavanpoor, M., Doesch, A. O., Katus, H. A. & Gleissner, C. A. Innate immunity, (2016).

Analyzing the Release of Copeptin from the Heart in Acute Myocardial Infarction Using a Transcoronary Gradient Model. Boeckel, J. N., Oppermann, J., Anadol, R., Fichtlscherer, S., Zeiher, A. M. & Keller, T. Scientific reports 6, 20812, (2016).

Classification of Adamts Binding Sites: The First Step toward Selective Adamts7 Inhibitors. Muller, M., Kessler, T., Schunkert, H., Erdmann, J. & Tennstedt, S. Biochemical and biophysical research communications, (2016).

The Endoplasmic Reticulum Chaperone Calnexin Is a Nadph Oxidase Nox4 Interacting Protein. Prior, K. K., Wittig, I., Leisegang, M. S., Groenendyk, J., Weissmann, N., Michalak, M., Jansen-Durr, P., Shah, A. M. & Brandes, R. P. The Journal of biological chemistry, (2016).

Micrornas as Biomarkers for Acute Atrial Remodeling in Marathon Runners (the Mirathon Study - a Sub-Study of the Munich Marathon Study). Clauss, S., Wakili, R., Hildebrand, B., Kaab, S., Hoster, E., Klier, I., Martens, E., Hanley, A., Hanssen, H., Halle, M. & Nickel, T. PloS one 11, e0148599, (2016).

Epigenetic Suppression of Inos Expression in Human Endothelial Cells: A Potential Role of Ezh2-Mediated H3k27me3. Dreger, H., Ludwig, A., Weller, A., Baumann, G., Stangl, V. & Stangl, K. Genomics, (2016).

The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells—a Potential Target for Pharmacological Intervention in Cardiovascular Diseases. Vukicevic, T., Schulz, M., Faust, D. & Klussmann, E. Front. Pharmacol, (2016).

High Spatial Resolution Cardiovascular Magnetic Resonance at 7.0 Tesla in Patients with Hypertrophic Cardiomyopathy - First Experiences: Lesson Learned from 7.0 Tesla. Prothmann, M., von Knobelsdorff-Brenkenhoff, F., Topper, A., Dieringer, M. A., Shahid, E., Graessl, A., Rieger, J., Lysiak, D., Thalhammer, C., Huelnhagen, T., Kellman, P., Niendorf, T. & Schulz-Menger, J. PloS one 11, e0148066, (2016).

Intestinal Congestion and Right Ventricular Dysfunction: A Link with Appetite Loss, Inflammation, and Cachexia in Chronic Heart Failure. Valentova, M., Von Haehling, S., Bauditz, J., Doehner, W., Ebner, N., Bekfani, T., Elsner, S., Sliziuk, V., Scherbakov, N., Murin, J., Anker, S. D. & Sandek, A. European heart journal, (2016).

Reply to the Letter Regarding the Article "Incidence, Determinants and Prognostic Relevance of Cardiogenic Shock in Takotsubo Cardiomyopathy". Stiermaier, T., Thiele, H. & Eitel, I. European heart journal. Acute cardiovascular care, (2016).

Predictors of Permanent Pacemaker Implantations and New-Onset Conduction Abnormalities with the Sapien 3 Balloon-Expandable Transcatheter Heart Valve. Husser, O., Pellegrini, C., Kessler, T., Burgdorf, C., Thaller, H., Mayr, N. P., Kasel, A. M., Kastrati, A., Schunkert, H. & Hengstenberg, C. JACC. Cardiovascular interventions 9, 244-254, (2016).

Cardiac Positron Emission Tomography: A Clinical Perspective. Polte, C. L., Burck, I., Gjertsson, P., Lomsky, M., Nekolla, S. G. & Nagel, E. Current Cardiovascular Imaging Reports, (2016).

Micrornas as a Diagnostic Tool for Heart Failure and Atrial Fibrillation. Weckbach, L. T., Grabmaier, U., Clauss, S. & Wakili, R. Current opinion in pharmacology 27, 24-30, (2016).

[Typical Atrial Flutter : Diagnosis and Therapy]. Thomas, D., Eckardt, L., Estner, H. L., Kuniss, M., Meyer, C., Neuberger, H. R., Sommer, P., Steven, D., Voss, F. & Bonnemeier, H. Herzschrittmachertherapie & Elektrophysiologie, (2016).

A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation. Schaefer, A., Schneeberger, Y., Stenzig, J., Biermann, D., Jelinek, M., Reichenspurner, H., Eschenhagen, T., Ehmke, H. & Schwoerer, A. P. PloS one 11, e0148259, (2016).

Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue. Jacob, F., Yonis, A. Y., Cuello, F., Luther, P., Schulze, T., Eder, A., Streichert, T., Mannhardt, I., Hirt, M. N., Schaaf, S., Stenzig, J., Force, T., Eschenhagen, T. & Hansen, A. PloS one 11, e0145937, (2016).

Endothelial Dicer Promotes Atherosclerosis and Vascular Inflammation by Mirna-103-Mediated Suppression of Klf4. Hartmann, P., Zhou, Z., Natarelli, L., Wei, Y., Nazari-Jahantigh, M., Zhu, M., Grommes, J., Steffens, S., Weber, C. & Schober, A. Nature communications 7, 10521, (2016).

Cardiovascular Biomarkers in Paired Maternal and Umbilical Cord Blood Samples at Term and near Term Delivery. Blohm, M. E., Arndt, F., Sandig, J., Diehl, W., Zeller, T., Mueller, G. C., Schlesner, C., Mir, T. S., Blankenberg, S., Hecher, K., Singer, D. & Weil, J. Early human development 94, 7-12, (2016).

Effects of Different Weight Loss Intervention Programmes in Health Clubs - an Observational Multicenter Study. Wanjek, M., Senner, V., Scharhag-Rosenberger, F. & Halle, M. European journal of sport science, 1-9, (2016).

S-Glutathiolation Impairs Phosphoregulation and Function of Cardiac Myosin-Binding Protein C in Human Heart Failure. Stathopoulou, K., Wittig, I., Heidler, J., Piasecki, A., Richter, F., Diering, S., van der Velden, J., Buck, F., Donzelli, S., Schroder, E., Wijnker, P. J., Voigt, N., Dobrev, D., Sadayappan, S., Eschenhagen, T., Carrier, L., Eaton, P. & Cuello, F. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2016).

Genetic Associations at 53 Loci Highlight Cell Types and Biological Pathways Relevant for Kidney Function. Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B. et al. Nature communications 7, 10023, (2016).

Neutrophils Orchestrate Post-Myocardial Infarction Healing by Polarizing Macrophages Towards a Reparative Phenotype. Horckmans, M., Ring, L., Duchene, J., Santovito, D., Schloss, M. J., Drechsler, M., Weber, C., Soehnlein, O. & Steffens, S. European heart journal, (2016).

Current Therapy and Outcome of Eisenmenger Syndrome: Data of the German National Register for Congenital Heart Defects. Diller, G.-P., Korten, M.-A., Bauer, U. M., Miera, O., Tutarel, O., Kaemmerer, H., Berger, F., Baumgartner, H. & Investigators, a. G. C. N. f. C. H. D. European heart journal, (2015).

Blood Oxygenation Level-Dependent Cmr-Derived Measures in Critical Limb Ischemia and Changes with Revascularization. Bajwa, A., Wesolowski, R., Patel, A., Saha, P., Ludwinski, F., Ikram, M., Albayati, M., Smith, A., Nagel, E. & Modarai, B. Journal of the American College of Cardiology 67, 420-431, (2016).

New Loci for Body Fat Percentage Reveal Link between Adiposity and Cardiometabolic Disease Risk. Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, A. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. et al. Nature communications 7, 10495, (2016).

Genome-Wide Meta-Analysis Uncovers Novel Loci Influencing Circulating Leptin Levels. Kilpelainen, T. O., Carli, J. F., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, A. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikainen, L. P., Eriksson, J. et al. Nature communications 7, 10494, (2016).

Multivessel Versus Culprit Lesion Only Percutaneous Revascularization Plus Potential Staged Revascularization in Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock: Design and Rationale of Culprit-Shock Trial. Thiele, H., Desch, S., Piek, J. J., Stepinska, J., Oldroyd, K., Serpytis, P., Montalescot, G., Noc, M., Huber, K., Fuernau, G., de Waha, S., Meyer-Saraei, R., Schneider, S., Windecker, S., Savonitto, S., Briggs, A., Torremante, P., Vrints, C., Schuler, G., Ceglarek, U. et al. American heart journal 172, 160-169, (2016).

Stem Cell Mechanobiology: 3d Micropillars Guide the Mechanobiology of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (Adv. Healthcare Mater. 3/2016). Palankar, R., Glaubitz, M., Martens, U., Medvedev, N., von der Ehe, M., Felix, S. B., Munzenberg, M. & Delcea, M. Advanced healthcare materials 5, 334, (2016).

Tolerability and Feasibility of Beta-Blocker Titration in Hfpef Versus Hfref: Insights from the Cibis-Eld Trial. Edelmann, F., Musial-Bright, L., Gelbrich, G., Trippel, T., Radenovic, S., Wachter, R., Inkrot, S., Loncar, G., Tahirovic, E., Celic, V., Veskovic, J., Zdravkovic, M., Lainscak, M., Apostolovic, S., Neskovic, A. N., Pieske, B., Dungen, H. D., Investigators, C.-E. & Project Multicenter Trials in the Competence Network Heart, F. JACC. Heart failure 4, 140-149, (2016).

Micrornas as Biomarkers for Acute Atrial Remodeling in Marathon Runners (the Mirathon Study - a Sub-Study of the Munich Marathon Study). Clauss, S., Wakili, R., Hildebrand, B., Kaab, S., Hoster, E., Klier, I., Martens, E., Hanley, A., Hanssen, H., Halle, M. & Nickel, T. PloS one 11, e0148599, (2016).

Foxo1 Couples Metabolic Activity and Growth State in the Vascular Endothelium. Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M. F., Lim, R., Zimmermann, B., Aspalter, I. M., Franco, C. A., Boettger, T., Braun, T., Fruttiger, M., Rajewsky, K., Keller, C., Bruning, J. C., Gerhardt, H., Carmeliet, P. & Potente, M. Nature, (2016).



Severe Prinzmetal-Type Coronary Artery Spasm Causing Recurrent St-Segment Elevation and Reversible Obstruction of a Bioresorbable Scaffold. Gori, T., Sechtem, U. & Munzel, T. JACC. Cardiovascular interventions 9, 195-197, (2016).  

Selective Phosphorylation of Pka Targets after Beta-Adrenergic Receptor Stimulation Impairs Myofilament Function in Mybpc3-Targeted Hcm Mouse Model. Najafi, A., Sequeira, V., Helmes, M., Bollen, I. A., Goebel, M., Regan, J. A., Carrier, L., Kuster, D. W. & van der Velden, J. Cardiovascular research, (2016).

The Multiple Proarrhythmic Roles of Cardiac Calcium-Handling Abnormalities: Triggered Activity, Conduction Abnormalities, Beat-to-Beat Variability, and Adverse Remodelling. Heijman, J., Schirmer, I. & Dobrev, D. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).

Genome-Wide Association Study and Targeted Metabolomics Identifies Sex-Specific Association of Cps1 with Coronary Artery Disease. Hartiala, J. A., Tang, W. H., Wang, Z., Crow, A. L., Stewart, A. F., Roberts, R., McPherson, R., Erdmann, J., Willenborg, C., Hazen, S. L. & Allayee, H. Nature communications 7, 10558, (2016).

The Persisting Gender Gap in Hypertension Management and Control in Germany: 1998 and 2008-2011. Sarganas, G. & Neuhauser, H. K. Hypertension research : official journal of the Japanese Society of Hypertension, (2016).

Bifurcations, Chaos, and Sensitivity to Parameter Variations in the Sato Cardiac Cell Model. Otte, S., Berg, S., Luther, S. & Parlitz, U. Communications in Nonlinear Science and Numerical Simulation, (2016).

Left Atrial Appendage Morphology, Echocardiographic Characterization, Procedural Data and in-Hospital Outcome of Patients Receiving Left Atrial Appendage Occlusion Device Implantation: A Prospective Observational Study. Fastner, C., Behnes, M., Sartorius, B., Yildiz, M., Mashayekhi, K., El-Battrawy, I., Lehmann, R., Baumann, S., Becher, T., Borggrefe, M. & Akin, I. BMC cardiovascular disorders 16, 25, (2016).

Dnmt1 and Hdac2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition. Tan, X., Xu, X., Zeisberg, M. & Zeisberg, E. M. PloS one 11, e0147816, (2016).

Inhibition of Camkii Attenuates Progressing Disruption of Ca Homeostasis Upon Left Ventricular Assist Device Implantation in Human Heart Failure. Fischer, T. H., Kleinwachter, A., Herting, J., Eiringhaus, J., Hartmann, N., Renner, A., Gummert, J., Haverich, A., Schmitto, J. D. & Sossalla, S. Artificial organs, (2016).

Thrombus Aspiration in Patients with St-Segment Elevation Myocardial Infarction Presenting Late after Symptom Onset. Desch, S., Stiermaier, T., de Waha, S., Lurz, P., Gutberlet, M., Sandri, M., Mangner, N., Boudriot, E., Woinke, M., Erbs, S., Schuler, G., Fuernau, G., Eitel, I. & Thiele, H. JACC. Cardiovascular interventions 9, 113-122, (2016).

Biodegradable Polymers Influence the Effect of Atorvastatin on Human Coronary Artery Cells. Strohbach, A., Begunk, R., Petersen, S., Felix, S. B., Sternberg, K. & Busch, R. International journal of molecular sciences 17, (2016).

Influence of Essential Amino Acids on Muscle Mass and Muscle Strength in Patients with Cerebral Stroke During Early Rehabilitation: Protocol and Rationale of a Randomized Clinical Trial (Amino-Stroke Study). Scherbakov, N., Ebner, N., Sandek, A., Meisel, A., Haeusler, K. G., von Haehling, S., Anker, S. D., Dirnagl, U., Joebges, M. & Doehner, W. BMC neurology 16, 10, (2016).

The Challenges and Impact of Microvascular Injury in St-Elevation Myocardial Infarction. Reinstadler, S. J., Stiermaier, T., Fuernau, G., de Waha, S., Desch, S., Metzler, B., Thiele, H. & Eitel, I. Expert review of cardiovascular therapy, 1-13, (2016).

From Single Variants to Protein Cascades: Multiscale Modeling of Single Nucleotide Variant Sets in Genetic Disorders. Mueller, S. C., Sommer, B., Backes, C., Haas, J., Meder, B., Meese, E. & Keller, A. The Journal of biological chemistry 291, 1582-1590, (2016).

Veno-Venous Double Lasso Pull-and-Push Technique for Transseptal Retrieval of an Embolized Watchman Occluder. Fastner, C., Lehmann, R., Behnes, M., Sartorius, B., Borggrefe, M. & Akin, I. Cardiovascular Revascularization Medicine, (2016).

Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis. Sroubek, J., Probst, V., Mazzanti, A., Delise, P., Castro Hevia, J., Ohkubo, K., Zorzi, A., Champagne, J., Kostopoulou, A., Yin, X., Napolitano, C., Milan, D. J., Wilde, A., Sacher, F., Borggrefe, M., Ellinor, P. T., Theodorakis, G., Nault, I., Corrado, D., Watanabe, I. et al. Circulation, (2016).

Molecular Multimodality Imaging: Has a Long-Standing Dream Come True? Joner, M., Giacoppo, D. & Kastrati, A. European heart journal, (2016).

Mendelian Randomization for the Identification of Causal Pathways in Atherosclerotic Vascular Disease. Jansen, H., Lieb, W. & Schunkert, H. Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, (2016).

Outcome of Surgical or Endovascular Treatment of Giant Intracranial Aneurysms, with Emphasis on Age, Aneurysm Location, and Unruptured Aneuryms - a Systematic Review and Meta-Analysis. Dengler, J., Maldaner, N., Glasker, S., Endres, M., Wagner, M., Malzahn, U., Heuschmann, P. U., Vajkoczy, P. & Giant Intracranial Aneurysm Study, G. Cerebrovascular diseases 41, 187-198, (2016).

Microvascular Ischemia in Hypertrophic Cardiomyopathy: New Insights from High-Resolution Combined Quantification of Perfusion and Late Gadolinium Enhancement. Villa, A. D., Sammut, E., Zarinabad, N., Carr-White, G., Lee, J., Bettencourt, N., Razavi, R., Nagel, E. & Chiribiri, A. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 18, 4, (2016).

Sex-Specific Differences in Genetic and Nongenetic Determinants of Mean Platelet Volume: Results from the Gutenberg Health Study. Panova-Noeva, M., Schulz, A., Hermanns, M. I., Grossmann, V., Pefani, E., Spronk, H. M., Laubert-Reh, D., Binder, H., Beutel, M., Pfeiffer, N., Blankenberg, S., Zeller, T., Munzel, T., Lackner, K. J., Ten Cate, H. & Wild, P. S. Blood 127, 251-259, (2016).

High Inorganic Phosphate Causes Dnmt1 Phosphorylation and Subsequent Fibrotic Fibroblast Activation. Tan, X., Xu, X., Zeisberg, E. M. & Zeisberg, M. Biochemical and biophysical research communications, (2016).

Histone Acetylation and Histone Acetyltransferases Show Significant Alterations in Human Abdominal Aortic Aneurysm. Han, Y., Tanios, F., Reeps, C., Zhang, J., Schwamborn, K., Eckstein, H. H., Zernecke, A. & Pelisek, J. Clinical epigenetics 8, 3, (2016).

Critical Role of Rage and Hmgb1 in Inflammatory Heart Disease. Bangert, A., Andrassy, M., Muller, A. M., Bockstahler, M., Fischer, A., Volz, C. H., Leib, C., Goser, S., Korkmaz-Icoz, S., Zittrich, S., Jungmann, A., Lasitschka, F., Pfitzer, G., Muller, O. J., Katus, H. A. & Kaya, Z. Proceedings of the National Academy of Sciences of the United States of America 113, E155-164, (2016).

One-Year Clinical Outcome after Ablation with a Novel Multipolar Irrigated Ablation Catheter for Treatment of Atrial Fibrillation: Potential Implications for Clinical Use. Wakili, R., Siebermair, J., Fichtner, S., Sinner, M. F., Klocker, E., Olesch, L., Hilberath, J. N., Sarai, S., Clauss, S., Sattler, S., Kaab, S. & Estner, H. L. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).

Update on Myocarditis and Inflammatory Cardiomyopathy: Reemergence of Endomyocardial Biopsy. Dominguez, F., Kuhl, U., Pieske, B., Garcia-Pavia, P. & Tschope, C. Revista espanola de cardiologia, (2016).

1-Year Outcomes of Everolimus-Eluting Bioresorbable Scaffolds Versus Everolimus-Eluting Stents : A Propensity-Matched Comparison of the Ghost-Eu and Xience V USA Registries. Tamburino, C., Capranzano, P., Gori, T., Latib, A., Lesiak, M., Nef, H., Caramanno, G., Naber, C., Mehilli, J., Di Mario, C., Sabate, M., Munzel, T., Colombo, A., Araszkiewicz, A., Wiebe, J., Geraci, S., Jensen, C., Mattesini, A., Brugaletta, S. & Capodanno, D. JACC: Cardiovascular Interventions, (2016).

Bias in High-Throughput Analysis of Mirnas and Implications for Biomarker Studies. Backes, C., Sedaghat-Hamedani, F., Frese, K., Hart, M., Ludwig, N., Meder, B., Meese, E. & Keller, A. Analytical chemistry, (2016).  

One-Year Clinical Outcome after Ablation with a Novel Multipolar Irrigated Ablation Catheter for Treatment of Atrial Fibrillation: Potential Implications for Clinical Use. Wakili, R., Siebermair, J., Fichtner, S., Sinner, M. F., Klocker, E., Olesch, L., Hilberath, J. N., Sarai, S., Clauss, S., Sattler, S., Kaab, S. & Estner, H. L. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).

Early Repolarization Pattern Is the Strongest Predictor of Arrhythmia Recurrence in Patients with Idiopathic Ventricular Fibrillation: Results from a Single Centre Long-Term Follow-up over 20 Years. Siebermair, J., Sinner, M. F., Beckmann, B. M., Laubender, R. P., Martens, E., Sattler, S., Fichtner, S., Estner, H. L., Kaab, S. & Wakili, R. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, (2016).

The Importance of Thrombin in Cerebral Injury and Disease. Krenzlin, H., Lorenz, V., Danckwardt, S., Kempski, O. & Alessandri, B. International journal of molecular sciences 17, (2016).

The Histone Demethylase Phf8 Is Essential for Endothelial Cell Migration. Gu, L., Hitzel, J., Moll, F., Kruse, C., Malik, R. A., Preussner, J., Looso, M., Leisegang, M. S., Steinhilber, D., Brandes, R. P. & Fork, C. PloS one 11, e0146645, (2016).

Predictive Value of Depressive Symptoms for All-Cause Mortality: Findings from the Prime Belfast Study Examining the Role of Inflammation and Cardiovascular Risk Markers. Hughes, M. F., Patterson, C. C., Appleton, K. M., Blankenberg, S., Woodside, J. V., Donnelly, M., Linden, G., Zeller, T., Esquirol, Y. & Kee, F. Psychosomatic medicine, (2016).

Normative Values for Carotid Intima Media Thickness and Its Progression: Are They Transferrable Outside of Their Cohort of Origin? Liao, X., Norata, G. D., Polak, J. F., Stehouwer, C. D., Catapano, A., Rundek, T., Ezhov, M., Sander, D., Thompson, S. G., Lorenz, M. W., group, P.-I. s., Balakhonova, T., Safarova, M., Grigore, L., Empana, J. P., Lin, H. J., McLachlan, S., Bokemark, L., Ronkainen, K., Schminke, U. et al. European journal of preventive cardiology, (2016).

Microstructured Nickel-Titanium Thin Film Leaflets for Hybrid Tissue Engineered Heart Valves Fabricated by Magnetron Sputter Deposition. Loger, K., Engel, A., Haupt, J., de Miranda, R. L., Lutter, G. & Quandt, E. Cardiovascular engineering and technology, (2016).

Myocardial Tissue Engineering for Cardiac Repair. Pecha, S., Eschenhagen, T. & Reichenspurner, H. J Heart Lung Transplant, (2016).

A Genome-Wide Analysis of DNA Methylation and Fine Particulate Matter Air Pollution in Three Study Populations: Kora F3, Kora F4, and the Normative Aging Study. Panni, T., Mehta, A. J., Schwartz, J. D., Baccarelli, A. A., Just, A. C., Wolf, K., Wahl, S., Cyrys, J., Kunze, S., Strauch, K., Waldenberger, M. & Peters, A. Environmental health perspectives, (2016).

T1-Mapping and Outcome in Nonischemic Cardiomyopathy. Puntmann, V. O., Carr-White, G., Jabbour, A., Yu, C.-Y., Gebker, R., Kelle, S., Hinojar, R., Doltra, A., Varma, N., Child, N., Rogers, T., Suna, G., Arroyo Ucar, E., Goodman, B., Khan, S., Dabir, D., Herrmann, E., Zeiher, A. M. & Nagel, E. J Am Coll Cardiol Img 9, 40-50, (2016).

Knock-out of Nexilin in Mice Leads to Dilated Cardiomyopathy and Endomyocardial Fibroelastosis. Aherrahrou, Z., Schlossarek, S., Stoelting, S., Klinger, M., Geertz, B., Weinberger, F., Kessler, T., Aherrahrou, R., Moreth, K., Bekeredjian, R., Hrabe de Angelis, M., Just, S., Rottbauer, W., Eschenhagen, T., Schunkert, H., Carrier, L. & Erdmann, J. Basic research in cardiology 111, 6, (2016).

Liquefaction Necrosis of Mitral Annulus Calcification. Bigvava, T., Schnackenburg, B., Nasser, S. B., Gebker, R., Berger, A., Pieske, B. & Kelle, S. International journal of cardiology 202, 59-61, (2016).

Ischaemic Cardiomyopathy: Pathophysiology, Assessment and the Role of Revascularisation. Briceno, N., Schuster, A., Lumley, M. & Perera, D. Heart, (2015).

The Year in Cardiology 2015: Prevention. Chapman, M. J., Blankenberg, S. & Landmesser, U. European heart journal, (2016).

Genome-Wide Association Analysis of Young Onset Stroke Identifies a Locus on Chromosome 10q25 near Habp2. Cheng, Y. C., Stanne, T. M., Giese, A. K., Ho, W. K., Traylor, M., Amouyel, P., Holliday, E. G., Malik, R., Xu, H., Kittner, S. J., Cole, J. W., O'Connell, J. R., Danesh, J., Rasheed, A., Zhao, W., Engelter, S., Grond-Ginsbach, C., Kamatani, Y., Lathrop, M., Leys, D. et al. Stroke; a journal of cerebral circulation, (2016).

Right Ventricular and Right Atrial Involvement Can Predict Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy? . Doesch, C., Lossnitzer, D., Rudic, B., Tueluemen, E., Budjan, J., Haubenreisser, H., Henzler, T., Schoenberg, S. O., Borggrefe, M. & Papavassiliu, T. Int J Med Sci 13, (2016).

Renal Denervation Improves Exercise Blood Pressure: Insights from a Randomized, Sham-Controlled Trial. Fengler, K., Heinemann, D., Okon, T., Rohnert, K., Stiermaier, T., von Roder, M., Besler, C., Muller, U., Hollriegel, R., Schuler, G., Desch, S. & Lurz, P. Clinical research in cardiology : official journal of the German Cardiac Society, (2016).

Comprehensive Multilevel in Vivo and in Vitro Analysis of Heart Rate Fluctuations in Mice by Ecg Telemetry and Electrophysiology. Fenske, S., Probstle, R., Auer, F., Hassan, S., Marks, V., Pauza, D. H., Biel, M. & Wahl-Schott, C. Nature protocols 11, 61-86, (2016).

DNA Methylation in an Engineered Heart Tissue Model of Cardiac Hypertrophy: Common Signatures and Effects of DNA Methylation Inhibitors. Stenzig, J., Hirt, M. N., Loser, A., Bartholdt, L. M., Hensel, J. T., Werner, T. R., Riemenschneider, M., Indenbirken, D., Guenther, T., Muller, C., Hubner, N., Stoll, M. & Eschenhagen, T. Basic research in cardiology 111, 9, (2016).

Analyzing Illumina Gene Expression Microarray Data Obtained from Human Whole Blood Cell and Blood Monocyte Samples. Teumer, A., Schurmann, C., Schillert, A., Schramm, K., Ziegler, A. & Prokisch, H. Methods in molecular biology 1368, 85-97, (2016).

Common Variation in Atrial Fibrillation: Navigating the Path from Genetic Association to Mechanism. Tucker, N. R., Clauss, S. & Ellinor, P. T. Cardiovascular research, (2016).