Proteomics


Förderkennzeichen

81Z7400172

Projektnummer

524

Institution
Universitätsmedizin Greifswald
Projektleiter
Uwe Völker
Standort
Greifswald
Kurzbeschreibung

The identification of new biomarkers from easily obtainable biomaterials like blood or urine is a key in individualized approaches for diagnostics and therapy. Proteomics provides … 

The identification of new biomarkers from easily obtainable biomaterials like blood or urine is a key in individualized approaches for diagnostics and therapy. Proteomics provides promising approaches that are ivestigated worldwide for many different diseases. The major aim of this project is analyse unique population-based cohorts in Greifswald which can be used as control groups for investigations in patients. Furthermore, proteomics shall provide characterictic proteome profiles for primary and secondary prevention approaches of cardiovascular diseases that can be used for intervention monitoring or as prognostic factors. Complementary transcriptome analyses to baseline and during the intervention (follow-up) will be done and a comprehensive data analysis of transcriptome, proteome and metabolome data will be carried out for risk stratification and therapeutic prognosis in DCM and heart failure.

Projektart
Standortprojekt
Stichwörter
proteomics, transcriptomics, integrated data analysis, risk stratification, molecular intervention monitoring
Topic
genetics of cardiovascular diseases
Fördersumme
€ 1.429.880,02
Beginn
01.01.2013
Ende
31.12.2018